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Transfer RNA Biogenesis - Leishmania donovani
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AEukaryotic type
B 5'processing factors
C Ribonucrease P
B 3'processing and CCA adding factors
C 3'processing factors
D LDBPK_365040 hypothetical protein K17710 PTCD1; pentatricopeptide repeat domain-containing protein 1
C CCA adding factors
B tRNA spricing factors
C tRNA splicing endonuclease complex
C tRNA splicing ligase complex
C Other tRNA splicing factors
B tRNA transport factors
C tRNA export factors
D LDBPK_251460 GTP-binding protein, putative K07936 RAN; GTP-binding nuclear protein Ran
D LDBPK_020090 exportin T (tRNA exportin)-like protein K14288 XPOT; exportin-T
D LDBPK_321160 exportin 1, putative K14290 XPO1; exportin-1
D LDBPK_170170 elongation factor 1-alpha K03231 EEF1A; elongation factor 1-alpha
D LDBPK_211050 hypothetical protein K08876 SCYL1; SCY1-like protein 1
D LDBPK_332930 GTP-binding protein, putative K24887 GTPBP1; GTP-binding protein 1
C tRNA import factors
B Aminoacyl-tRNA synthetases (AARSs)
C Multi-aminoacyl-tRNA synthetase complex (MSC)
D LDBPK_303290 glutamyl-tRNA synthetase, putative K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D LDBPK_365870 isoleucyl-tRNA synthetase, putative K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D LDBPK_131000 leucyl-tRNA synthetase, putative K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D LDBPK_210890 methionyl-tRNA synthetase, putative K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D LDBPK_151490 glutaminyl-tRNA synthetase, putative K01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]
D LDBPK_271230 arginyl-tRNA synthetase, putative K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D LDBPK_150270 lysyl-tRNA synthetase, putative K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D LDBPK_300130 lysyl-tRNA synthetase, putative K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D LDBPK_300470 aspartyl-tRNA synthetase, putative K22503 DARS1; aspartyl-tRNA synthetase [EC:6.1.1.12]
D LDBPK_211120 aspartyl-tRNA synthetase, putative K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
C Other AARSs
D LDBPK_221390 alanyl-tRNA synthetase, putative K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D LDBPK_150720 hypothetical protein K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D LDBPK_342110 asparaginyl-tRNA synthetase, putative K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
D LDBPK_364030 glycyl tRNA synthetase, putative K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D LDBPK_351420 threonyl-tRNA synthetase, putative K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D LDBPK_110100 seryl-tRNA synthetase, putative K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D LDBPK_120255 hypothetical protein K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D LDBPK_303170 valyl-tRNA synthetase, putative K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D LDBPK_300650 histidyl-tRNA synthetase, putative K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D LDBPK_320920 phenylalanyl-tRNA synthetase alpha chain, putative K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D LDBPK_191010 phenylalanyl-tRNA synthetase, putative K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D LDBPK_141460 tyrosyl-tRNA synthetase, putative K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D LDBPK_290060 tryptophanyl-tRNA synthetase, putative K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D LDBPK_230340 tryptophanyl-tRNA synthetase, putative K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
C Trans-editing factors
D LDBPK_362870 D-tyrosyl-tRNA deacylase, putative K07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
D LDBPK_343140 hypothetical protein K07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
C AARS associated factors
B tRNA modification factors
C Deaminases
D LDBPK_100780 deaminase, putative K15441 TAD2; tRNA-specific adenosine deaminase 2 [EC:3.5.4.-]
D LDBPK_322210 hypothetical protein K15442 TAD3; tRNA-specific adenosine deaminase 3
C Dihydorouridine synthases
D LDBPK_360500 dihydrouridine synthase domain protein-like protein K05543 DUS2; tRNA-dihydrouridine synthase 2 [EC:1.3.1.91]
D LDBPK_170400 hypothetical protein K05544 DUS3; tRNA-dihydrouridine synthase 3 [EC:1.3.1.89]
C Methylthiotransferase
C Methyltransferases
D LDBPK_201680 hypothetical protein K15332 TRMT2A; tRNA (uracil-5-)-methyltransferase [EC:2.1.1.-]
D LDBPK_322790 hypothetical protein K15333 TRM3; tRNA guanosine-2'-O-methyltransferase [EC:2.1.1.34]
D LDBPK_362300 hypothetical protein K15335 NSUN2; tRNA (cytosine34-C5)-methyltransferase [EC:2.1.1.203]
D LDBPK_292650 hypothetical protein K15335 NSUN2; tRNA (cytosine34-C5)-methyltransferase [EC:2.1.1.203]
D LDBPK_160320 hypothetical protein K15429 TRM5; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]
D LDBPK_282570 hypothetical protein K07442 TRM61; tRNA (adenine57-N1/adenine58-N1)-methyltransferase catalytic subunit [EC:2.1.1.219 2.1.1.220]
D LDBPK_366030 hypothetical protein K03256 TRM6; tRNA (adenine58-N1)-methyltransferase non-catalytic subunit
D LDBPK_020350 FtsJ-like methyltransferase, putative K14864 FTSJ1; tRNA (cytidine32/guanosine34-2'-O)-methyltransferase [EC:2.1.1.205]
D LDBPK_355200 tRNA (guanine-N(7)-)-methyltransferase, putative K03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]
D LDBPK_353650 hypothetical protein K00599 METTL6; tRNA N(3)-methylcytidine methyltransferase METTL6 [EC:2.1.1.-]
D LDBPK_362780 hypothetical protein K15444 TRM9; tRNA (uracil-5-)-methyltransferase TRM9 [EC:2.1.1.229]
D LDBPK_051010 methyltransferase-like protein K15430 TRM11; tRNA (guanine10-N2)-methyltransferase [EC:2.1.1.214]
D LDBPK_060170 hypothetical protein K15448 TRM112; multifunctional methyltransferase subunit TRM112
D LDBPK_050750 hypothetical protein K15449 TYW1; tRNA wybutosine-synthesizing protein 1 [EC:4.1.3.44]
D LDBPK_151610 hypothetical protein K15449 TYW1; tRNA wybutosine-synthesizing protein 1 [EC:4.1.3.44]
D LDBPK_030050 hypothetical protein K07055 TRM12; tRNA wybutosine-synthesizing protein 2 [EC:2.5.1.114]
D LDBPK_090710 hypothetical protein K15450 TYW3; tRNA wybutosine-synthesizing protein 3 [EC:2.1.1.282]
D LDBPK_352990 hypothetical protein K15451 PPM2; tRNA wybutosine-synthesizing protein 4 [EC:2.1.1.290 2.3.1.231]
C Psudouridine synthases
D LDBPK_190990 tRNA pseudouridine synthase A-like protein K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D LDBPK_260410 pseudouridylate synthase-like protein K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D LDBPK_301570 pseudouridine synthase A-like protein, putative K01855 PUS3; tRNA pseudouridine38/39 synthase [EC:5.4.99.45]
D LDBPK_366000 hypothetical protein K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
D LDBPK_323580 hypothetical protein K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
D LDBPK_110540 hypothetical protein K07583 PUS10; tRNA pseudouridine synthase 10 [EC:5.4.99.25]
C Thiolation factors
D LDBPK_070280 tRNA-methyl transferase, putative K21027 TRMU; tRNA-5-taurinomethyluridine 2-sulfurtransferase [EC:2.8.1.14]
D LDBPK_366380 hypothetical protein K14168 CTU1; cytoplasmic tRNA 2-thiolation protein 1 [EC:2.7.7.-]
D LDBPK_130680 hypothetical protein K14169 CTU2; cytoplasmic tRNA 2-thiolation protein 2
D LDBPK_270930 cysteine desulfurase, putative K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D LDBPK_342690 ubiquitin related modifier (urm1)-like protein K12161 URM1; ubiquitin related modifier 1
D LDBPK_271570 molybdopterin synthase sulphurylase-like protein, putative K11996 MOCS3; adenylyltransferase and sulfurtransferase [EC:2.7.7.80 2.8.1.11]
C KEOPS/EKC complex
D LDBPK_250900 protein kinase, putative K08851 TP53RK; TP53 regulating kinase and related kinases [EC:2.7.11.1]
D LDBPK_310110 O-sialoglycoprotein endopeptidase, putative K01409 OSGEP; N6-L-threonylcarbamoyladenine synthase [EC:2.3.1.234]
D LDBPK_340860 hypothetical protein K15902 LAGE3; EKC/KEOPS complex subunit LAGE3/PCC1
C Elongator complex
C Elongator related proteins
D LDBPK_262660 hypothetical protein K15455 DPH3; diphthamide biosynthesis protein 3
D LDBPK_344020 protein serine/threonine phosphatase, putativee K15427 SIT4; serine/threonine-protein phosphatase PP1-1 [EC:3.1.3.16]
C Other tRNA modification factors
D LDBPK_282210 hypothetical protein K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D LDBPK_290980 hypothetical protein K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
D LDBPK_301800 queuine tRNA-ribosyltransferase, putative K00777 QTRT1; queuine tRNA-ribosyltransferase catalytic subunit [EC:2.4.2.64]
D LDBPK_270030 hypothetical protein K15407 QTRT2; queuine tRNA-ribosyltransferase accessory subunit
D LDBPK_365650 selenophosphate synthetase, putative K01008 selD; selenide, water dikinase [EC:2.7.9.3]
B tRNA degradation factors
C TRAMP complex
D LDBPK_364190 hypothetical protein K03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19]
D LDBPK_363150 ATP-dependent RNA helicase, putative K12598 MTR4; ATP-dependent RNA helicase DOB1 [EC:5.6.2.6]
C Rapid tRNA decay (RTD) pathway factors
D LDBPK_060260 5'-3' exonuclease, putative K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]
D LDBPK_361870 exoribonuclease 2, putative K12619 XRN2; 5'-3' exoribonuclease 2 [EC:3.1.13.-]
D LDBPK_230600 5'-3' exonuclease XRNC, putative K12619 XRN2; 5'-3' exoribonuclease 2 [EC:3.1.13.-]
C Other tRNA degradation factors
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AProkaryotic type
B 5'processing factors
C Ribonucrease P
B 3'processing and CCA adding factors
C 3'processing factors
C CCA adding factors
B tRNA spricing factors
C tRNA splicing endonucleases
C tRNA splicing ligases
C Other tRNA splicing factors
B tRNA transport factors
C tRNA export factors
B Aminoacyl-tRNA synthetases (AARSs)
C Multi-aminoacyl-tRNA synthetase complex (MSC)
D LDBPK_131000 leucyl-tRNA synthetase, putative K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
C Other AARSs
D LDBPK_141460 tyrosyl-tRNA synthetase, putative K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D LDBPK_290060 tryptophanyl-tRNA synthetase, putative K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D LDBPK_230340 tryptophanyl-tRNA synthetase, putative K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D LDBPK_351420 threonyl-tRNA synthetase, putative K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D LDBPK_365870 isoleucyl-tRNA synthetase, putative K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D LDBPK_150270 lysyl-tRNA synthetase, putative K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D LDBPK_300130 lysyl-tRNA synthetase, putative K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D LDBPK_221390 alanyl-tRNA synthetase, putative K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D LDBPK_150720 hypothetical protein K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D LDBPK_303170 valyl-tRNA synthetase, putative K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D LDBPK_210890 methionyl-tRNA synthetase, putative K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D LDBPK_110100 seryl-tRNA synthetase, putative K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D LDBPK_211120 aspartyl-tRNA synthetase, putative K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D LDBPK_120255 hypothetical protein K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D LDBPK_303290 glutamyl-tRNA synthetase, putative K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D LDBPK_151490 glutaminyl-tRNA synthetase, putative K01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]
D LDBPK_271230 arginyl-tRNA synthetase, putative K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D LDBPK_320920 phenylalanyl-tRNA synthetase alpha chain, putative K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D LDBPK_191010 phenylalanyl-tRNA synthetase, putative K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D LDBPK_300650 histidyl-tRNA synthetase, putative K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D LDBPK_342110 asparaginyl-tRNA synthetase, putative K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
D LDBPK_161170 tyrosyl or methionyl-tRNA synthetase-like protein K01894 gluQ; glutamyl-Q tRNA(Asp) synthetase [EC:6.1.1.-]
C Trans-editing factors
D LDBPK_362870 D-tyrosyl-tRNA deacylase, putative K07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
D LDBPK_343140 hypothetical protein K07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
B tRNA modification factors
C Deaminases
C Dihydorouridine synthases
C Methylthiotransferases
C Methyltransferases
D LDBPK_355200 tRNA (guanine-N(7)-)-methyltransferase, putative K03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]
C Psudouridine synthases
D LDBPK_190990 tRNA pseudouridine synthase A-like protein K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D LDBPK_260410 pseudouridylate synthase-like protein K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D LDBPK_366000 hypothetical protein K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
D LDBPK_323580 hypothetical protein K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
C Thiolation factors
D LDBPK_270930 cysteine desulfurase, putative K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
C KEOPS/EKC complex
D LDBPK_250900 protein kinase, putative K08851 TP53RK; TP53 regulating kinase and related kinases [EC:2.7.11.1]
D LDBPK_310110 O-sialoglycoprotein endopeptidase, putative K01409 OSGEP; N6-L-threonylcarbamoyladenine synthase [EC:2.3.1.234]
C Other tRNA modification factors
D LDBPK_290980 hypothetical protein K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
D LDBPK_365650 selenophosphate synthetase, putative K01008 selD; selenide, water dikinase [EC:2.7.9.3]
D LDBPK_282210 hypothetical protein K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D LDBPK_240470 ubiquitin-activating enzyme, putative K22132 tcdA; tRNA threonylcarbamoyladenosine dehydratase
B tRNA degradation factors
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: February 29, 2024