+F Repair protein KO
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DNA Repair and Recombination Proteins - Lacticaseibacillus rhamnosus LOCK908
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
C BER (base exicision repair)
D DNA glycosylases
E LOCK908_1034 Uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E LOCK908_1612 DNA-3-methyladenine glycosylase II K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E LOCK908_0660 A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E LOCK908_1551 Endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
E LOCK908_0322 DinG family ATP-dependent helicase K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D LOCK908_2638 Mutator mutT protein (7,8-dihydro-8-oxoguanine-triphosphatase) K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D LOCK908_2672 MutT/Nudix family protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D LOCK908_0115 Hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D LOCK908_0209 Nudix dNTPase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D LOCK908_2398 Deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
C BER (base exicision repair)
D DNA glycosylases
E LOCK908_1034 Uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E LOCK908_1612 DNA-3-methyladenine glycosylase II K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E LOCK908_0660 A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E LOCK908_2268 DNA-3-methyladenine glycosylase K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E LOCK908_0521 DNA-3-methyladenine glycosylase K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E LOCK908_1793 Formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E LOCK908_1551 Endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E LOCK908_1040 Exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E LOCK908_1595 Endonuclease IV K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
D RecJ
E LOCK908_1635 Single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E LOCK908_1113 DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E LOCK908_1794 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E LOCK908_0996 Excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
E LOCK908_2709 Excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
E LOCK908_0994 Excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
E LOCK908_1410 Excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C
E LOCK908_2036 DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E LOCK908_1112 ATP-dependent DNA helicase UvrD/PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E LOCK908_2025 Hypothetical protein K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E LOCK908_1794 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E LOCK908_1113 DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F LOCK908_2570 DNA-directed RNA polymerase beta subunit K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F LOCK908_2569 DNA-directed RNA polymerase beta' subunit K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F LOCK908_2532 DNA-directed RNA polymerase alpha subunit K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F LOCK908_2634 DNA-directed RNA polymerase delta subunit K03048 rpoE; DNA-directed RNA polymerase subunit delta
F LOCK908_1710 DNA-directed RNA polymerase omega subunit K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F LOCK908_2599 Transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E LOCK908_2289 DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
E LOCK908_0768 Recombination inhibitory protein MutS2 K07456 mutS2; DNA mismatch repair protein MutS2
D Molecular matchmaker
E LOCK908_2288 DNA mismatch repair protein MutL K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
D DNA exonucleases
E LOCK908_1719 Exodeoxyribonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E LOCK908_1718 Exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E LOCK908_1425 DNA polymerase III alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E LOCK908_1655 DNA polymerase III alpha subunit K03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7]
E LOCK908_0002 DNA polymerase III beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E LOCK908_1389 DNA polymerase III delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E LOCK908_2314 DNA polymerase III delta prime subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E LOCK908_1039 Exonuclease K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E LOCK908_2320 DNA polymerase III subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E LOCK908_1113 DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E LOCK908_2036 DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E LOCK908_1112 ATP-dependent DNA helicase UvrD/PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E LOCK908_2025 Hypothetical protein K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E LOCK908_0012 Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E LOCK908_0014 Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E LOCK908_1361 RecD-like DNA helicase YrrC K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E LOCK908_0954 RecA protein K03553 recA; recombination protein RecA
E LOCK908_2725 RecA protein K03553 recA; recombination protein RecA
E LOCK908_0745 Holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E LOCK908_0746 Holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E LOCK908_1708 Helicase PriA essential for oriC/DnaA-independent DNA replication K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E LOCK908_0656 Exonuclease SbcC K03546 sbcC; DNA repair protein SbcC/Rad50
E LOCK908_0655 Exonuclease SbcD K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E LOCK908_0954 RecA protein K03553 recA; recombination protein RecA
E LOCK908_2725 RecA protein K03553 recA; recombination protein RecA
E LOCK908_2397 DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
E LOCK908_0005 DNA recombination and repair protein RecF K03629 recF; DNA replication and repair protein RecF
E LOCK908_1697 ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E LOCK908_1635 Single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E LOCK908_1586 DNA recombination and repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E LOCK908_2318 Recombination protein RecR K06187 recR; recombination protein RecR
E LOCK908_1714 DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
E LOCK908_1548 Recombination protein RecU K03700 recU; recombination protein U
E LOCK908_0745 Holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E LOCK908_0746 Holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
D AddAB pathway proteins
E LOCK908_1559 ATP-dependent nuclease, subunit A K16898 addA; ATP-dependent helicase/nuclease subunit A [EC:5.6.2.4 3.1.-.-]
E LOCK908_1560 ATP-dependent nuclease, subunit B K16899 addB; ATP-dependent helicase/nuclease subunit B [EC:5.6.2.4 3.1.-.-]
D Other HR factor
D Archaeal homologous recombinant proteins
E LOCK908_0656 Exonuclease SbcC K03546 sbcC; DNA repair protein SbcC/Rad50
E LOCK908_0655 Exonuclease SbcD K03547 sbcD; DNA repair protein SbcD/Mre11
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F LOCK908_0007 DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F LOCK908_0006 DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F LOCK908_1469 DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F LOCK908_1444 DNA-binding protein HBsu K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F LOCK908_1635 Single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F LOCK908_1586 DNA recombination and repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F LOCK908_2318 Recombination protein RecR K06187 recR; recombination protein RecR
F LOCK908_1113 DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
E Supressor
F LOCK908_1438 ATP-dependent DNA helicase, RecQ family K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F LOCK908_1139 ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F LOCK908_0996 Excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
F LOCK908_2709 Excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
F LOCK908_0994 Excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D LOCK908_0754 DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
C Other SOS response factors
D LOCK908_0954 RecA protein K03553 recA; recombination protein RecA
D LOCK908_2725 RecA protein K03553 recA; recombination protein RecA
D LOCK908_0708 SOS-response repressor and protease LexA K01356 lexA; repressor LexA [EC:3.4.21.88]
D LOCK908_1714 DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D LOCK908_0012 Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D LOCK908_0014 Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D LOCK908_1867 regulatory protein RecX K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D LOCK908_1558 DinG family ATP-dependent helicase YoaA K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
C Modulation of nucleotide pools
D LOCK908_2638 Mutator mutT protein (7,8-dihydro-8-oxoguanine-triphosphatase) K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D LOCK908_2672 MutT/Nudix family protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D LOCK908_0115 Hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D LOCK908_0209 Nudix dNTPase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D LOCK908_2398 Deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D LOCK908_1536 Ribonucleotide reductase of class Ib (aerobic), alpha subunit K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D LOCK908_1537 Ribonucleotide reductase of class Ib (aerobic), beta subunit K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
D LOCK908_0756 3'-to-5' oligoribonuclease A K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]
D LOCK908_2858 3'-to-5' oligoribonuclease A K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: August 19, 2024