+F Repair protein KO
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DNA Repair and Recombination Proteins - Legionella waltersii
%
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D SAMEA4504053_2772 phrB; deoxyribodipyrimidine photolyase phrB K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E SAMEA4504053_0593 ung; Uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E SAMEA4504053_1194 DNA-3-methyladenine glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E SAMEA4504053_1229 mutY; A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E SAMEA4504053_3410 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D SAMEA4504053_1698 mutT_1; mutator MutT protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SAMEA4504053_0946 dut; deoxyuridinetriphosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D SAMEA4504053_2347 ada; transcription regulator protein K10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response / methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]
D SAMEA4504053_2772 phrB; deoxyribodipyrimidine photolyase phrB K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D SAMEA4504053_2746 Deoxyribodipyrimidine photolyase-related protein K06876 phrB; (6-4)DNA photolyase [EC:4.1.99.13]
C BER (base exicision repair)
D DNA glycosylases
E SAMEA4504053_0593 ung; Uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E SAMEA4504053_1194 DNA-3-methyladenine glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E SAMEA4504053_1229 mutY; A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E SAMEA4504053_1720 tag; 3-methyladenine DNA glycosylase K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E SAMEA4504053_0879 mutM; formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E SAMEA4504053_3410 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E SAMEA4504053_0983 exoA; exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E SAMEA4504053_0984 xthA; exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D RecJ
E SAMEA4504053_1889 recJ; single-stranded-DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E SAMEA4504053_2213 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E SAMEA4504053_0128 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E SAMEA4504053_0703 uvrA; excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
E SAMEA4504053_3143 uvrC; excinuclease ABC subunit K03703 uvrC; excinuclease ABC subunit C
E SAMEA4504053_2041 uvrD; DNA dependent ATPase I and helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E SAMEA4504053_0128 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E SAMEA4504053_2213 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F SAMEA4504053_0642 rpoB; RNA polymerase B-subunit K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F SAMEA4504053_0643 rpoC; DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F SAMEA4504053_0673 rpoA; DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F SAMEA4504053_2254 rpoZ; RNA polymerase omega subunit K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F SAMEA4504053_2218 mfd; transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E SAMEA4504053_1994 mutS; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
D Molecular matchmaker
E SAMEA4504053_3197 mutL; DNA mismatch repair protein MutL K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
E SAMEA4504053_1715 mutH; DNA mismatch repair protein MutH K03573 mutH; DNA mismatch repair protein MutH
D DNA exonucleases
E SAMEA4504053_1155 xseA; exodeoxyribonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E SAMEA4504053_2566 xseB; exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E SAMEA4504053_2209 dnaE; DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E SAMEA4504053_0002 dnaN; DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E SAMEA4504053_3129 holC; DNA polymerase III subunit chi K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
E SAMEA4504053_1523 holA; DNA polymerase III subunit delta K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E SAMEA4504053_1573 holB; DNA polymerase III, delta prime subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E SAMEA4504053_1556 dnaQ; DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E SAMEA4504053_3257 dnaX; DNA polymerase III subunit gamma/tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E SAMEA4504053_2213 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E SAMEA4504053_2041 uvrD; DNA dependent ATPase I and helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E SAMEA4504053_0305 ssb_1; single-strand DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E SAMEA4504053_0372 ssb_2; single-strand DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E SAMEA4504053_0675 ssb_3; single strand binding protein K03111 ssb; single-strand DNA-binding protein
E SAMEA4504053_2176 ssb_4; single-strand DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E SAMEA4504053_0989 dam; DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E SAMEA4504053_1988 recA; recombination protein RecA K03553 recA; recombination protein RecA
E SAMEA4504053_1482 ruvA; Holliday junction ATP-dependent DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E SAMEA4504053_1803 ruvB; Holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E SAMEA4504053_1481 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E SAMEA4504053_3394 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
D RecFOR pathway proteins
E SAMEA4504053_1988 recA; recombination protein RecA K03553 recA; recombination protein RecA
E SAMEA4504053_2563 DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
E SAMEA4504053_0003 recF; RecF recombinational DNA repair ATPase K03629 recF; DNA replication and repair protein RecF
E SAMEA4504053_2281 recG; ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E SAMEA4504053_2977 ATP-dependent DNA helicase K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E SAMEA4504053_1889 recJ; single-stranded-DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E SAMEA4504053_2227 recO; DNA repair protein RecO (recombination protein O) K03584 recO; DNA repair protein RecO (recombination protein O)
E SAMEA4504053_3259 recR; recombinational DNA repair protein RecR K06187 recR; recombination protein RecR
E SAMEA4504053_3348 recN; DNA repair ATPase K03631 recN; DNA repair protein RecN (Recombination protein N)
E SAMEA4504053_1410 rdgC; exonuclease involved in removal of stalled replication fork K03554 rdgC; recombination associated protein RdgC
E SAMEA4504053_1482 ruvA; Holliday junction ATP-dependent DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E SAMEA4504053_1803 ruvB; Holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E SAMEA4504053_1481 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
D Other HR factor
D Archaeal homologous recombinant proteins
E SAMEA4504053_1899 putative ATPase K06915 herA; DNA double-strand break repair helicase HerA and related ATPase
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F SAMEA4504053_1590 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F SAMEA4504053_0004 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F SAMEA4504053_3086 topA; DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F SAMEA4504053_2057 hupB; HupB DNA binding protein HU-beta K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F SAMEA4504053_1889 recJ; single-stranded-DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F SAMEA4504053_2227 recO; DNA repair protein RecO (recombination protein O) K03584 recO; DNA repair protein RecO (recombination protein O)
F SAMEA4504053_3259 recR; recombinational DNA repair protein RecR K06187 recR; recombination protein RecR
F SAMEA4504053_2213 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
F SAMEA4504053_0871 fis_1; global DNA-binding transcriptional dual regulator K03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein
F SAMEA4504053_1543 fis_2; DNA-binding protein fis K03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein
F SAMEA4504053_1927 fis_3; Fis transcriptional activator K03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein
F SAMEA4504053_3215 ihfA; integration host factor (IHF) alpha subunit K04764 ihfA; integration host factor subunit alpha
F SAMEA4504053_3468 ihfB; integration host factor beta subunit K05788 ihfB; integration host factor subunit beta
E Supressor
F SAMEA4504053_1195 recQ; Superfamily II DNA helicase K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F SAMEA4504053_0703 uvrA; excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D SAMEA4504053_1643 umuC; SOS mutagenesis and repair UmuC protein K03502 umuC; DNA polymerase V
D SAMEA4504053_1642 umuD; SOS (error prone) mutagenesis protein UmuD (RumA) K03503 umuD; DNA polymerase V [EC:3.4.21.-]
C Other SOS response factors
D SAMEA4504053_1988 recA; recombination protein RecA K03553 recA; recombination protein RecA
D SAMEA4504053_3348 recN; DNA repair ATPase K03631 recN; DNA repair protein RecN (Recombination protein N)
D SAMEA4504053_0305 ssb_1; single-strand DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D SAMEA4504053_0372 ssb_2; single-strand DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D SAMEA4504053_0675 ssb_3; single strand binding protein K03111 ssb; single-strand DNA-binding protein
D SAMEA4504053_2176 ssb_4; single-strand DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D SAMEA4504053_1987 recX; regulatory protein RecX K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D SAMEA4504053_3340 rep; ATP-dependent DNA helicase K03656 rep; ATP-dependent DNA helicase Rep [EC:5.6.2.4]
D SAMEA4504053_1342 dinG; ATP dependent DNA helicase (DEAD box family) Rad3 K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
C Modulation of nucleotide pools
D SAMEA4504053_1698 mutT_1; mutator MutT protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SAMEA4504053_0946 dut; deoxyuridinetriphosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D SAMEA4504053_1958 nrdA; ribonucleoside-diphosphate reductase subunit alpha K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D SAMEA4504053_1959 nrdB; ribonucleoside-diphosphate reductase subunit beta K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024