+F Repair protein KO
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DNA Repair and Recombination Proteins - Methanobrevibacter sp. AbM4
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D Abm4_0828 ogt; 6-O-methylguanine DNA methyltransferase Ogt K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E Abm4_1673 ogg; 8-oxoguanine DNA glycosylase Ogg K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18]
E Abm4_1194 nth; endonuclease III Nth K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
E Abm4_1647 pcn; DNA polymerase sliding clamp subunit PCNA family Pcn K04802 PCNA; proliferating cell nuclear antigen
E Abm4_0178 fen; flap endonuclease Fen K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
E Abm4_0234 dnlI; ATP-dependent DNA ligase DnlI K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
E Abm4_1694 rpaI; replication factor A RpaI K07466 RFA1; replication factor A1
D Other NER factors
E Abm4_0234 dnlI; ATP-dependent DNA ligase DnlI K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
E Abm4_1694 rpaI; replication factor A RpaI K07466 RFA1; replication factor A1
D RFC (replication factor C)
D Other MMR factors
E Abm4_1647 pcn; DNA polymerase sliding clamp subunit PCNA family Pcn K04802 PCNA; proliferating cell nuclear antigen
E Abm4_0234 dnlI; ATP-dependent DNA ligase DnlI K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
E Abm4_1694 rpaI; replication factor A RpaI K07466 RFA1; replication factor A1
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
D Abm4_1647 pcn; DNA polymerase sliding clamp subunit PCNA family Pcn K04802 PCNA; proliferating cell nuclear antigen
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D Abm4_1650 NUDIX domain-containing protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Abm4_1668 NUDIX domain-containing protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Abm4_1032 NUDIX domain-containing protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Abm4_0206 dut; dUTP diphosphatase Dut K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D Abm4_0828 ogt; 6-O-methylguanine DNA methyltransferase Ogt K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E Abm4_1167 DNA-3-methyladenine glycosylase I K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E Abm4_1194 nth; endonuclease III Nth K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E Abm4_1150 xth; exodeoxyribonuclease III Xth K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E Abm4_1479 endonuclease IV K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
D RecJ
E Abm4_0083 recJ1; ssDNA exonuclease RecJ1 K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E Abm4_1137 recJ2; ssDNA exonuclease RecJ2 K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
D DNA polymerase I
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E Abm4_0861 uvrA; excinuclease ABC A subunit UvrA K03701 uvrA; excinuclease ABC subunit A
E Abm4_0862 uvrB; excinuclease ABC B subunit UvrB K03702 uvrB; excinuclease ABC subunit B
E Abm4_0814 uvrC; excinuclease ABC C subunit UvrC K03703 uvrC; excinuclease ABC subunit C
E Abm4_0863 ATP-dependent DNA helicase UvrD/REP family K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
E TRCF (transcription-repair coupling factor)
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E Abm4_1402 DNA mismatch repair ATPase MutS family K07456 mutS2; DNA mismatch repair protein MutS2
D Molecular matchmaker
D Strand discrimination factor
D DNA exonucleases
E Abm4_1395 xseA; exodeoxyribonuclease VII large subunit XseA K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E Abm4_1396 xseB; exodeoxyribonuclease VII small subunit XseB K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
D DNA ligase
D Other MMR factors
E Abm4_0863 ATP-dependent DNA helicase UvrD/REP family K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E Abm4_1018 type II DNA modification methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E Abm4_0879 rad50; DNA double-strand break repair protein Rad50 K03546 sbcC; DNA repair protein SbcC/Rad50
E Abm4_0880 mre11; DNA double-strand break repair protein Mre11 K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E Abm4_0083 recJ1; ssDNA exonuclease RecJ1 K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E Abm4_1137 recJ2; ssDNA exonuclease RecJ2 K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D AddAB pathway proteins
D Other HR factor
E Abm4_0106 CRISPR-associated endonuclease Cas1 K15342 cas1; CRISP-associated protein Cas1
E Abm4_1082 CRISPR-associated endonuclease Cas1 K15342 cas1; CRISP-associated protein Cas1
D Archaeal homologous recombinant proteins
E Abm4_1693 radA; DNA repair and recombination protein RadA K04483 radA; DNA repair protein RadA
E Abm4_0279 radB; DNA repair and recombination protein RadB K04484 radB; DNA repair protein RadB
E Abm4_1602 hjc; archaeal Holliday junction resolvase Hjc K03552 hjr; holliday junction resolvase [EC:3.1.21.10]
E Abm4_0879 rad50; DNA double-strand break repair protein Rad50 K03546 sbcC; DNA repair protein SbcC/Rad50
E Abm4_0880 mre11; DNA double-strand break repair protein Mre11 K03547 sbcD; DNA repair protein SbcD/Mre11
E Abm4_0881 ATPase K06915 herA; DNA double-strand break repair helicase HerA and related ATPase
E Abm4_0882 NurA domain-containing protein K25510 nurA; DNA double-strand break repair nuclease NurA [EC:3.1.-.-]
E Abm4_0534 DEAD/DEAH box helicase domain-containing protein K03726 helS; ATP-dependent DNA helicase [EC:5.6.2.4]
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F Abm4_0185 topA; DNA topoisomerase I TopA K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F Abm4_0083 recJ1; ssDNA exonuclease RecJ1 K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F Abm4_1137 recJ2; ssDNA exonuclease RecJ2 K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E Facilitator
E Supressor
F Abm4_0861 uvrA; excinuclease ABC A subunit UvrA K03701 uvrA; excinuclease ABC subunit A
F Abm4_0862 uvrB; excinuclease ABC B subunit UvrB K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C Other SOS response factors
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D Abm4_0546 UvrD/REP family DNA helicase K03658 helD; DNA helicase IV [EC:5.6.2.4]
D Abm4_0389 DEAD/DEAH box helicase domain-containing protein K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
D Abm4_1378 DEAD/DEAH box helicase domain-containing protein K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
C Modulation of nucleotide pools
D Abm4_1650 NUDIX domain-containing protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Abm4_1668 NUDIX domain-containing protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Abm4_1032 NUDIX domain-containing protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Abm4_0206 dut; dUTP diphosphatase Dut K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
C Others
D Abm4_0966 hypothetical protein K22585 nreA; DNA repair protein NreA
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024