+D GENES KO #

  KEGG Orthology (KO) - Methanobacterium lacus

% ! A09100 Metabolism B B 09101 Carbohydrate metabolism C 00010 Glycolysis / Gluconeogenesis [PATH:mel00010] D Metbo_0582 protein of unknown function DUF100 K01622 K01622; fructose 1,6-bisphosphate aldolase/phosphatase [EC:4.1.2.13 3.1.3.11] D Metbo_1361 phospho-2-dehydro-3-deoxyheptonate aldolase K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10] D Metbo_2401 triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] D Metbo_1751 Glyceraldehyde-3-phosphate dehydrogenase K00150 gap2; glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) [EC:1.2.1.59] D Metbo_2379 Glyceraldehyde-3-phosphate dehydrogenase K00150 gap2; glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) [EC:1.2.1.59] D Metbo_2400 Phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3] D Metbo_1172 proposed homoserine kinase K15635 apgM; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12] D Metbo_2291 phosphonopyruvate decarboxylase-related protein K15635 apgM; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12] D Metbo_0814 Enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D Metbo_0380 phosphoenolpyruvate synthase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2] D Metbo_2051 Dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Metbo_0488 Pyruvate synthase K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1] D Metbo_0487 Pyruvate synthase K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1] D Metbo_0490 pyruvate/ketoisovalerate oxidoreductase, gamma subunit K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1] D Metbo_0489 pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1] D Metbo_2451 2-oxoacid:acceptor oxidoreductase, alpha subunit K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11] D Metbo_2408 2-oxoglutarate synthase K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11] D Metbo_1456 2-oxoacid:acceptor oxidoreductase, alpha subunit K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11] D Metbo_2450 pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11] D Metbo_2407 2-oxoglutarate synthase K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11] D Metbo_1457 pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11] D Metbo_1898 acetate/CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D Metbo_1715 acetate/CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D Metbo_2455 Butyrate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D Metbo_0567 acetate/CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D Metbo_1651 CoA-binding domain protein K24012 acdAB; acetate---CoA ligase (ADP-forming) [EC:6.2.1.13] D Metbo_2461 Phosphoglucosamine mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2] C 00020 Citrate cycle (TCA cycle) [PATH:mel00020] D Metbo_2051 Dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Metbo_2451 2-oxoacid:acceptor oxidoreductase, alpha subunit K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11] D Metbo_2408 2-oxoglutarate synthase K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11] D Metbo_1456 2-oxoacid:acceptor oxidoreductase, alpha subunit K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11] D Metbo_2450 pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11] D Metbo_2407 2-oxoglutarate synthase K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11] D Metbo_1457 pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11] D Metbo_2406 2-oxoglutarate synthase K00177 korC; 2-oxoglutarate ferredoxin oxidoreductase subunit gamma [EC:1.2.7.3] D Metbo_2409 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein K00176 korD; 2-oxoglutarate ferredoxin oxidoreductase subunit delta [EC:1.2.7.3] D Metbo_0628 succinyl-CoA synthetase, alpha subunit K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5] D Metbo_2405 Succinyl-CoA ligase (ADP-forming) subunit beta K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5] D Metbo_2113 succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1] D Metbo_2112 succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1] D Metbo_0429 hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit K01677 E4.2.1.2AA; fumarate hydratase subunit alpha [EC:4.2.1.2] D Metbo_0484 hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit K01677 E4.2.1.2AA; fumarate hydratase subunit alpha [EC:4.2.1.2] D Metbo_0382 Fe-S type hydro-lyase tartrate/fumarate beta region K01678 E4.2.1.2AB; fumarate hydratase subunit beta [EC:4.2.1.2] D Metbo_0744 hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit K01678 E4.2.1.2AB; fumarate hydratase subunit beta [EC:4.2.1.2] D Metbo_0579 Malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37] D Metbo_0764 acetyl-CoA carboxylase, biotin carboxylase K01959 pycA; pyruvate carboxylase subunit A [EC:6.4.1.1] D Metbo_0395 oxaloacetate decarboxylase alpha subunit K01960 pycB; pyruvate carboxylase subunit B [EC:6.4.1.1] D Metbo_0488 Pyruvate synthase K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1] D Metbo_0487 Pyruvate synthase K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1] D Metbo_0490 pyruvate/ketoisovalerate oxidoreductase, gamma subunit K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1] D Metbo_0489 pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1] C 00030 Pentose phosphate pathway [PATH:mel00030] D Metbo_1018 Ribose-5-phosphate isomerase A K01807 rpiA; ribose 5-phosphate isomerase A [EC:5.3.1.6] D Metbo_0071 Bifunctional enzyme fae/hps K13812 fae-hps; bifunctional enzyme Fae/Hps [EC:4.2.1.147 4.1.2.43] D Metbo_2333 Dimethylmenaquinone methyltransferase K08093 hxlA; 3-hexulose-6-phosphate synthase [EC:4.1.2.43] D Metbo_2522 6-phospho 3-hexuloisomerase K08094 hxlB; 6-phospho-3-hexuloisomerase [EC:5.3.1.27] D Metbo_0617 6-phospho 3-hexuloisomerase K08094 hxlB; 6-phospho-3-hexuloisomerase [EC:5.3.1.27] D Metbo_1927 Deoxyribose-phosphate aldolase K01619 deoC; deoxyribose-phosphate aldolase [EC:4.1.2.4] D Metbo_2461 Phosphoglucosamine mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2] D Metbo_2203 ribose-phosphate pyrophosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1] D Metbo_0582 protein of unknown function DUF100 K01622 K01622; fructose 1,6-bisphosphate aldolase/phosphatase [EC:4.1.2.13 3.1.3.11] D Metbo_1361 phospho-2-dehydro-3-deoxyheptonate aldolase K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10] C 00040 Pentose and glucuronate interconversions [PATH:mel00040] D Metbo_0903 nucleotide sugar dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22] D Metbo_2084 UTP-glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D Metbo_0114 L-fuculose-phosphate aldolase K01628 fucA; L-fuculose-phosphate aldolase [EC:4.1.2.17] C 00051 Fructose and mannose metabolism [PATH:mel00051] D Metbo_2461 Phosphoglucosamine mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2] D Metbo_1294 GDP-mannose 4,6-dehydratase K01711 gmd; GDPmannose 4,6-dehydratase [EC:4.2.1.47] D Metbo_0839 GDP-mannose 4,6-dehydratase K01711 gmd; GDPmannose 4,6-dehydratase [EC:4.2.1.47] D Metbo_0114 L-fuculose-phosphate aldolase K01628 fucA; L-fuculose-phosphate aldolase [EC:4.1.2.17] D Metbo_0582 protein of unknown function DUF100 K01622 K01622; fructose 1,6-bisphosphate aldolase/phosphatase [EC:4.1.2.13 3.1.3.11] D Metbo_1361 phospho-2-dehydro-3-deoxyheptonate aldolase K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10] D Metbo_2401 triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] C 00052 Galactose metabolism [PATH:mel00052] D Metbo_0865 UDP-glucose 4-epimerase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2] D Metbo_1293 UDP-glucose 4-epimerase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2] D Metbo_2083 UDP-glucose 4-epimerase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2] D Metbo_2084 UTP-glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D Metbo_2461 Phosphoglucosamine mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2] C 00053 Ascorbate and aldarate metabolism D Metbo_0903 nucleotide sugar dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22] C 00500 Starch and sucrose metabolism [PATH:mel00500] D Metbo_2084 UTP-glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D Metbo_1747 trehalose-phosphatase K01087 otsB; trehalose 6-phosphate phosphatase [EC:3.1.3.12] D Metbo_2461 Phosphoglucosamine mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2] C 00520 Amino sugar and nucleotide sugar metabolism [PATH:mel00520] D Metbo_2109 Glucosamine--fructose-6-phosphate aminotransferase (isomerizing) K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] D Metbo_1749 Glutamine--fructose-6-phosphate transaminase (isomerizing) K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] D Metbo_2292 Phosphoglucosamine mutase K03431 glmM; phosphoglucosamine mutase [EC:5.4.2.10] D Metbo_2293 Glucosamine-1-phosphate N-acetyltransferase K23144 K23144; UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.7.7.24 2.7.7.83 2.3.1.157 2.3.1.276] D Metbo_1950 UDP-N-acetylglucosamine 2-epimerase K01791 wecB; UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing) [EC:5.1.3.14] D Metbo_0912 nucleotide sugar dehydrogenase K02472 wecC; UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase [EC:1.1.1.336] D Metbo_0866 nucleotide sugar dehydrogenase K13015 wbpA; UDP-N-acetyl-D-glucosamine dehydrogenase [EC:1.1.1.136] D Metbo_0724 UDP-glucuronate decarboxylase K08678 UXS1; UDP-glucuronate decarboxylase [EC:4.1.1.35] D Metbo_2461 Phosphoglucosamine mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2] D Metbo_2084 UTP-glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D Metbo_0903 nucleotide sugar dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22] D Metbo_0865 UDP-glucose 4-epimerase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2] D Metbo_1293 UDP-glucose 4-epimerase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2] D Metbo_2083 UDP-glucose 4-epimerase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2] D Metbo_1294 GDP-mannose 4,6-dehydratase K01711 gmd; GDPmannose 4,6-dehydratase [EC:4.2.1.47] D Metbo_0839 GDP-mannose 4,6-dehydratase K01711 gmd; GDPmannose 4,6-dehydratase [EC:4.2.1.47] C 00620 Pyruvate metabolism [PATH:mel00620] D Metbo_1898 acetate/CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D Metbo_1715 acetate/CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D Metbo_2455 Butyrate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D Metbo_0567 acetate/CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D Metbo_0488 Pyruvate synthase K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1] D Metbo_0487 Pyruvate synthase K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1] D Metbo_0490 pyruvate/ketoisovalerate oxidoreductase, gamma subunit K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1] D Metbo_0489 pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1] D Metbo_2451 2-oxoacid:acceptor oxidoreductase, alpha subunit K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11] D Metbo_2408 2-oxoglutarate synthase K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11] D Metbo_1456 2-oxoacid:acceptor oxidoreductase, alpha subunit K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11] D Metbo_2450 pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11] D Metbo_2407 2-oxoglutarate synthase K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11] D Metbo_1457 pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11] D Metbo_2051 Dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Metbo_1651 CoA-binding domain protein K24012 acdAB; acetate---CoA ligase (ADP-forming) [EC:6.2.1.13] D Metbo_2036 Acetolactate synthase K00158 spxB; pyruvate oxidase [EC:1.2.3.3] D Metbo_0415 Lactaldehyde dehydrogenase K19266 E1.2.1.22; lactaldehyde dehydrogenase [EC:1.2.1.22] D Metbo_1762 Glyoxalase/bleomycin resistance protein/dioxygenase K01759 GLO1; lactoylglutathione lyase [EC:4.4.1.5] D Metbo_0031 Glyoxalase/bleomycin resistance protein/dioxygenase K01759 GLO1; lactoylglutathione lyase [EC:4.4.1.5] D Metbo_0454 beta-lactamase domain protein K01069 gloB; hydroxyacylglutathione hydrolase [EC:3.1.2.6] D Metbo_0242 beta-lactamase domain protein K01069 gloB; hydroxyacylglutathione hydrolase [EC:3.1.2.6] D Metbo_0764 acetyl-CoA carboxylase, biotin carboxylase K01959 pycA; pyruvate carboxylase subunit A [EC:6.4.1.1] D Metbo_0395 oxaloacetate decarboxylase alpha subunit K01960 pycB; pyruvate carboxylase subunit B [EC:6.4.1.1] D Metbo_0579 Malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37] D Metbo_0429 hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit K01677 E4.2.1.2AA; fumarate hydratase subunit alpha [EC:4.2.1.2] D Metbo_0484 hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit K01677 E4.2.1.2AA; fumarate hydratase subunit alpha [EC:4.2.1.2] D Metbo_0382 Fe-S type hydro-lyase tartrate/fumarate beta region K01678 E4.2.1.2AB; fumarate hydratase subunit beta [EC:4.2.1.2] D Metbo_0744 hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit K01678 E4.2.1.2AB; fumarate hydratase subunit beta [EC:4.2.1.2] D Metbo_0380 phosphoenolpyruvate synthase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2] D Metbo_1377 Propanoyl-CoA C-acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Metbo_0066 isopropylmalate/citramalate/homocitrate synthase K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13] D Metbo_2071 isopropylmalate/citramalate/homocitrate synthase K10977 aksA; methanogen homocitrate synthase [EC:2.3.3.14 2.3.3.-] C 00630 Glyoxylate and dicarboxylate metabolism [PATH:mel00630] D Metbo_1898 acetate/CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D Metbo_1715 acetate/CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D Metbo_2455 Butyrate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D Metbo_0567 acetate/CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D Metbo_0579 Malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37] D Metbo_1377 Propanoyl-CoA C-acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Metbo_2262 Phosphoglycolate phosphatase K22223 pgp; phosphoglycolate phosphatase [EC:3.1.3.18] D Metbo_2484 glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2] D Metbo_1856 Glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D Metbo_0162 Glycine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D Metbo_1243 Glycine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D Metbo_2051 Dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] C 00640 Propanoate metabolism [PATH:mel00640] D Metbo_1898 acetate/CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D Metbo_1715 acetate/CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D Metbo_2455 Butyrate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D Metbo_0567 acetate/CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D Metbo_1651 CoA-binding domain protein K24012 acdAB; acetate---CoA ligase (ADP-forming) [EC:6.2.1.13] D Metbo_2051 Dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Metbo_0488 Pyruvate synthase K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1] D Metbo_0487 Pyruvate synthase K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1] D Metbo_0490 pyruvate/ketoisovalerate oxidoreductase, gamma subunit K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1] D Metbo_0489 pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1] D Metbo_2405 Succinyl-CoA ligase (ADP-forming) subunit beta K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5] D Metbo_0628 succinyl-CoA synthetase, alpha subunit K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5] C 00650 Butanoate metabolism [PATH:mel00650] D Metbo_1377 Propanoyl-CoA C-acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Metbo_0674 Phosphate butyryltransferase K00634 ptb; phosphate butyryltransferase [EC:2.3.1.19] D Metbo_2113 succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1] D Metbo_2112 succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1] D Metbo_1424 glutamate decarboxylase K01580 E4.1.1.15; glutamate decarboxylase [EC:4.1.1.15] D Metbo_1654 glutamate decarboxylase K01580 E4.1.1.15; glutamate decarboxylase [EC:4.1.1.15] D Metbo_0488 Pyruvate synthase K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1] D Metbo_0487 Pyruvate synthase K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1] D Metbo_0490 pyruvate/ketoisovalerate oxidoreductase, gamma subunit K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1] D Metbo_0489 pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1] D Metbo_2451 2-oxoacid:acceptor oxidoreductase, alpha subunit K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11] D Metbo_2408 2-oxoglutarate synthase K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11] D Metbo_1456 2-oxoacid:acceptor oxidoreductase, alpha subunit K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11] D Metbo_2450 pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11] D Metbo_2407 2-oxoglutarate synthase K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11] D Metbo_1457 pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11] D Metbo_1378 UPF0219 protein K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10] D Metbo_0092 acetolactate synthase, large subunit, biosynthetic type K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D Metbo_0566 Acetolactate synthase K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D Metbo_0093 acetolactate synthase, small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6] C 00660 C5-Branched dibasic acid metabolism [PATH:mel00660] D Metbo_0092 acetolactate synthase, large subunit, biosynthetic type K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D Metbo_0566 Acetolactate synthase K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D Metbo_0093 acetolactate synthase, small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6] D Metbo_2405 Succinyl-CoA ligase (ADP-forming) subunit beta K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5] D Metbo_0628 succinyl-CoA synthetase, alpha subunit K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5] D Metbo_2364 isopropylmalate/citramalate/homocitrate synthase K09011 cimA; (R)-citramalate synthase [EC:2.3.3.21] D Metbo_0169 3-isopropylmalate dehydratase large subunit K01703 leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35] D Metbo_0170 3-isopropylmalate dehydratase small subunit K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35] D Metbo_0171 3-isopropylmalate dehydrogenase K00052 leuB; 3-isopropylmalate dehydrogenase [EC:1.1.1.85] C 00562 Inositol phosphate metabolism [PATH:mel00562] D Metbo_2345 Inositol-phosphate phosphatase K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25] D Metbo_0397 Myo-inositol-1-phosphate synthase K01858 INO1; myo-inositol-1-phosphate synthase [EC:5.5.1.4] D Metbo_2401 triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] B B 09102 Energy metabolism C 00190 Oxidative phosphorylation [PATH:mel00190] D Metbo_2519 NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 nuoE; NADH-quinone oxidoreductase subunit E [EC:7.1.1.2] D Metbo_2518 NADH dehydrogenase (quinone) K00335 nuoF; NADH-quinone oxidoreductase subunit F [EC:7.1.1.2] D Metbo_2113 succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1] D Metbo_2112 succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1] D Metbo_0437 V-type ATP synthase alpha chain K02117 ATPVA; V/A-type H+/Na+-transporting ATPase subunit A [EC:7.1.2.2 7.2.2.1] D Metbo_0438 V-type ATP synthase beta chain K02118 ATPVB; V/A-type H+/Na+-transporting ATPase subunit B D Metbo_0435 V-type ATP synthase subunit C K02119 ATPVC; V/A-type H+/Na+-transporting ATPase subunit C D Metbo_0439 V-type ATP synthase subunit D K02120 ATPVD; V/A-type H+/Na+-transporting ATPase subunit D D Metbo_0434 V-type proton ATPase subunit E K02121 ATPVE; V/A-type H+/Na+-transporting ATPase subunit E D Metbo_0436 V-type ATP synthase subunit F K02122 ATPVF; V/A-type H+/Na+-transporting ATPase subunit F D Metbo_0431 ATP synthase H subunit K02107 ATPVG; V/A-type H+/Na+-transporting ATPase subunit G/H D Metbo_0432 V-type ATPase 116 kDa subunit K02123 ATPVI; V/A-type H+/Na+-transporting ATPase subunit I D Metbo_0433 ATP synthase subunit c K02124 ATPVK; V/A-type H+/Na+-transporting ATPase subunit K D Metbo_1031 plasma-membrane proton-efflux P-type ATPase K01535 PMA1; H+-transporting ATPase [EC:7.1.2.1] D Metbo_0603 Inorganic pyrophosphatase K01507 ppa; inorganic pyrophosphatase [EC:3.6.1.1] D Metbo_1585 polyphosphate kinase 1 K00937 ppk1; polyphosphate kinase [EC:2.7.4.1] C 00195 Photosynthesis C 00196 Photosynthesis - antenna proteins C 00710 Carbon fixation by Calvin cycle [PATH:mel00710] D Metbo_2400 Phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3] D Metbo_1751 Glyceraldehyde-3-phosphate dehydrogenase K00150 gap2; glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) [EC:1.2.1.59] D Metbo_2379 Glyceraldehyde-3-phosphate dehydrogenase K00150 gap2; glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) [EC:1.2.1.59] D Metbo_1018 Ribose-5-phosphate isomerase A K01807 rpiA; ribose 5-phosphate isomerase A [EC:5.3.1.6] D Metbo_2401 triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] D Metbo_0579 Malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37] C 00720 Other carbon fixation pathways [PATH:mel00720] D Metbo_0488 Pyruvate synthase K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1] D Metbo_0487 Pyruvate synthase K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1] D Metbo_0490 pyruvate/ketoisovalerate oxidoreductase, gamma subunit K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1] D Metbo_0489 pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1] D Metbo_0380 phosphoenolpyruvate synthase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2] D Metbo_0764 acetyl-CoA carboxylase, biotin carboxylase K01959 pycA; pyruvate carboxylase subunit A [EC:6.4.1.1] D Metbo_0395 oxaloacetate decarboxylase alpha subunit K01960 pycB; pyruvate carboxylase subunit B [EC:6.4.1.1] D Metbo_0579 Malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37] D Metbo_0429 hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit K01677 E4.2.1.2AA; fumarate hydratase subunit alpha [EC:4.2.1.2] D Metbo_0484 hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit K01677 E4.2.1.2AA; fumarate hydratase subunit alpha [EC:4.2.1.2] D Metbo_0382 Fe-S type hydro-lyase tartrate/fumarate beta region K01678 E4.2.1.2AB; fumarate hydratase subunit beta [EC:4.2.1.2] D Metbo_0744 hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit K01678 E4.2.1.2AB; fumarate hydratase subunit beta [EC:4.2.1.2] D Metbo_2113 succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1] D Metbo_2112 succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1] D Metbo_0043 L-aspartate oxidase K18209 tfrA; fumarate reductase (CoM/CoB) subunit A [EC:1.3.4.1] D Metbo_0664 succinate dehydrogenase and fumarate reductase iron-sulfur protein K18210 tfrB; fumarate reductase (CoM/CoB) subunit B [EC:1.3.4.1] D Metbo_0628 succinyl-CoA synthetase, alpha subunit K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5] D Metbo_2405 Succinyl-CoA ligase (ADP-forming) subunit beta K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5] D Metbo_1377 Propanoyl-CoA C-acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Metbo_2451 2-oxoacid:acceptor oxidoreductase, alpha subunit K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11] D Metbo_2408 2-oxoglutarate synthase K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11] D Metbo_1456 2-oxoacid:acceptor oxidoreductase, alpha subunit K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11] D Metbo_2450 pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11] D Metbo_2407 2-oxoglutarate synthase K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11] D Metbo_1457 pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11] D Metbo_2406 2-oxoglutarate synthase K00177 korC; 2-oxoglutarate ferredoxin oxidoreductase subunit gamma [EC:1.2.7.3] D Metbo_2409 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein K00176 korD; 2-oxoglutarate ferredoxin oxidoreductase subunit delta [EC:1.2.7.3] D Metbo_2515 formate dehydrogenase, alpha subunit K05299 fdhA; formate dehydrogenase (NADP+) alpha subunit [EC:1.17.1.10] D Metbo_0486 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein K00196 cooF; anaerobic carbon-monoxide dehydrogenase iron sulfur subunit D Metbo_0485 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein K00196 cooF; anaerobic carbon-monoxide dehydrogenase iron sulfur subunit D Metbo_0467 CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel K00197 cdhE; acetyl-CoA decarbonylase/synthase, CODH/ACS complex subunit gamma [EC:2.1.1.245] D Metbo_0466 CO dehydrogenase/acetyl-CoA synthase, delta subunit K00194 cdhD; acetyl-CoA decarbonylase/synthase, CODH/ACS complex subunit delta [EC:2.1.1.245] D Metbo_1898 acetate/CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D Metbo_1715 acetate/CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D Metbo_2455 Butyrate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D Metbo_0567 acetate/CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] C 00680 Methane metabolism [PATH:mel00680] D Metbo_2515 formate dehydrogenase, alpha subunit K05299 fdhA; formate dehydrogenase (NADP+) alpha subunit [EC:1.17.1.10] D Metbo_0462 Acetyl-CoA decarbonylase/synthase complex subunit alpha K00192 cdhA; anaerobic carbon-monoxide dehydrogenase, CODH/ACS complex subunit alpha [EC:1.2.7.4] D Metbo_0463 Acetyl-CoA decarbonylase/synthase complex subunit epsilon K00195 cdhB; anaerobic carbon-monoxide dehydrogenase, CODH/ACS complex subunit epsilon D Metbo_0464 CO dehydrogenase/acetyl-CoA synthase complex, beta subunit K00193 cdhC; acetyl-CoA decarbonylase/synthase, CODH/ACS complex subunit beta [EC:2.3.1.169] D Metbo_0467 CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel K00197 cdhE; acetyl-CoA decarbonylase/synthase, CODH/ACS complex subunit gamma [EC:2.1.1.245] D Metbo_0466 CO dehydrogenase/acetyl-CoA synthase, delta subunit K00194 cdhD; acetyl-CoA decarbonylase/synthase, CODH/ACS complex subunit delta [EC:2.1.1.245] D Metbo_0486 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein K00196 cooF; anaerobic carbon-monoxide dehydrogenase iron sulfur subunit D Metbo_0485 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein K00196 cooF; anaerobic carbon-monoxide dehydrogenase iron sulfur subunit D Metbo_0162 Glycine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D Metbo_1243 Glycine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D Metbo_0814 Enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D Metbo_0579 Malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37] D Metbo_0582 protein of unknown function DUF100 K01622 K01622; fructose 1,6-bisphosphate aldolase/phosphatase [EC:4.1.2.13 3.1.3.11] D Metbo_1361 phospho-2-dehydro-3-deoxyheptonate aldolase K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10] D Metbo_2522 6-phospho 3-hexuloisomerase K08094 hxlB; 6-phospho-3-hexuloisomerase [EC:5.3.1.27] D Metbo_0617 6-phospho 3-hexuloisomerase K08094 hxlB; 6-phospho-3-hexuloisomerase [EC:5.3.1.27] D Metbo_2333 Dimethylmenaquinone methyltransferase K08093 hxlA; 3-hexulose-6-phosphate synthase [EC:4.1.2.43] D Metbo_0071 Bifunctional enzyme fae/hps K13812 fae-hps; bifunctional enzyme Fae/Hps [EC:4.2.1.147 4.1.2.43] D Metbo_0576 glutamine amidotransferase class-II K22081 mgsA; methylamine---glutamate N-methyltransferase subunit A [EC:2.1.1.21] D Metbo_0575 glutamate synthase alpha subunit domain protein K22082 mgsB; methylamine---glutamate N-methyltransferase subunit B [EC:2.1.1.21] D Metbo_0573 Glutamate synthase (NADPH) K22083 mgsC; methylamine---glutamate N-methyltransferase subunit C [EC:2.1.1.21] D Metbo_2037 Glutamate synthase (NADPH) K22083 mgsC; methylamine---glutamate N-methyltransferase subunit C [EC:2.1.1.21] D Metbo_2509 formylmethanofuran dehydrogenase subunit A K00200 fwdA; formylmethanofuran dehydrogenase subunit A [EC:1.2.7.12] D Metbo_2510 formylmethanofuran dehydrogenase subunit B K00201 fwdB; formylmethanofuran dehydrogenase subunit B [EC:1.2.7.12] D Metbo_2508 formylmethanofuran dehydrogenase subunit C K00202 fwdC; formylmethanofuran dehydrogenase subunit C [EC:1.2.7.12] D Metbo_2511 molybdopterin dinucleotide-binding region K00203 fwdD; formylmethanofuran dehydrogenase subunit D [EC:1.2.7.12] D Metbo_2514 helix-turn-helix domain protein K00204 fwdH; 4Fe-4S ferredoxin D Metbo_2502 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein K00205 fwdF; 4Fe-4S ferredoxin D Metbo_2513 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein K00205 fwdF; 4Fe-4S ferredoxin D Metbo_2512 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein K11260 fwdG; 4Fe-4S ferredoxin D Metbo_2505 formylmethanofuran dehydrogenase subunit E region K11261 fwdE; formylmethanofuran dehydrogenase subunit E [EC:1.2.7.12] D Metbo_2052 formylmethanofuran dehydrogenase subunit E region K11261 fwdE; formylmethanofuran dehydrogenase subunit E [EC:1.2.7.12] D Metbo_0252 formylmethanofuran/tetrahydromethanopterin N-formyltransferase K00672 ftr; formylmethanofuran--tetrahydromethanopterin N-formyltransferase [EC:2.3.1.101] D Metbo_1272 Formylmethanofuran--tetrahydromethanopterin N-formyltransferase K00672 ftr; formylmethanofuran--tetrahydromethanopterin N-formyltransferase [EC:2.3.1.101] D Metbo_2195 Methenyltetrahydromethanopterin cyclohydrolase K01499 mch; methenyltetrahydromethanopterin cyclohydrolase [EC:3.5.4.27] D Metbo_0080 F420-dependent methylenetetrahydromethanopterin dehydrogenase K00319 mtd; methylenetetrahydromethanopterin dehydrogenase [EC:1.5.98.1] D Metbo_0218 coenzyme F420 hydrogenase, subunit alpha K00440 frhA; coenzyme F420 hydrogenase subunit alpha [EC:1.12.98.1] D Metbo_0863 coenzyme F420 hydrogenase/dehydrogenase beta subunit domain protein K00441 frhB; coenzyme F420 hydrogenase subunit beta [EC:1.12.98.1] D Metbo_0221 coenzyme F420 hydrogenase, subunit beta K00441 frhB; coenzyme F420 hydrogenase subunit beta [EC:1.12.98.1] D Metbo_0574 Coenzyme F420 hydrogenase K00441 frhB; coenzyme F420 hydrogenase subunit beta [EC:1.12.98.1] D Metbo_0219 coenzyme F420-reducing hydrogenase delta subunit K00442 frhD; coenzyme F420 hydrogenase subunit delta D Metbo_0220 coenzyme F420 hydrogenase, subunit gamma K00443 frhG; coenzyme F420 hydrogenase subunit gamma [EC:1.12.98.1] D Metbo_0510 5,10-methylenetetrahydromethanopterin reductase K00320 mer; 5,10-methylenetetrahydromethanopterin reductase [EC:1.5.98.2] D Metbo_0358 Tetrahydromethanopterin S-methyltransferase subunit A K00577 mtrA; tetrahydromethanopterin S-methyltransferase subunit A [EC:7.2.1.4] D Metbo_0357 Tetrahydromethanopterin S-methyltransferase subunit B K00578 mtrB; tetrahydromethanopterin S-methyltransferase subunit B [EC:7.2.1.4] D Metbo_0356 tetrahydromethanopterin S-methyltransferase, subunit C K00579 mtrC; tetrahydromethanopterin S-methyltransferase subunit C [EC:7.2.1.4] D Metbo_0355 Tetrahydromethanopterin S-methyltransferase subunit D K00580 mtrD; tetrahydromethanopterin S-methyltransferase subunit D [EC:7.2.1.4] D Metbo_0354 Tetrahydromethanopterin S-methyltransferase subunit E K00581 mtrE; tetrahydromethanopterin S-methyltransferase subunit E [EC:7.2.1.4] D Metbo_0359 tetrahydromethanopterin S-methyltransferase, F subunit K00582 mtrF; tetrahydromethanopterin S-methyltransferase subunit F [EC:7.2.1.4] D Metbo_0360 tetrahydromethanopterin S-methyltransferase, subunit G K00583 mtrG; tetrahydromethanopterin S-methyltransferase subunit G [EC:7.2.1.4] D Metbo_0361 Tetrahydromethanopterin S-methyltransferase subunit H K00584 mtrH; tetrahydromethanopterin S-methyltransferase subunit H [EC:7.2.1.4] D Metbo_0353 methyl-coenzyme M reductase, alpha subunit K00399 mcrA; methyl-coenzyme M reductase alpha subunit [EC:2.8.4.1] D Metbo_2281 methyl-coenzyme M reductase, alpha subunit K00399 mcrA; methyl-coenzyme M reductase alpha subunit [EC:2.8.4.1] D Metbo_0995 ABC transporter related protein K00400 K00400; methyl coenzyme M reductase system, component A2 D Metbo_2439 methyl coenzyme M reductase system, component A2 K00400 K00400; methyl coenzyme M reductase system, component A2 D Metbo_0508 methyl coenzyme M reductase system, component A2 K00400 K00400; methyl coenzyme M reductase system, component A2 D Metbo_0349 methyl-coenzyme M reductase, beta subunit K00401 mcrB; methyl-coenzyme M reductase beta subunit [EC:2.8.4.1] D Metbo_2278 methyl-coenzyme M reductase, beta subunit K00401 mcrB; methyl-coenzyme M reductase beta subunit [EC:2.8.4.1] D Metbo_0352 methyl-coenzyme M reductase, gamma subunit K00402 mcrG; methyl-coenzyme M reductase gamma subunit [EC:2.8.4.1] D Metbo_2280 methyl-coenzyme M reductase, gamma subunit K00402 mcrG; methyl-coenzyme M reductase gamma subunit [EC:2.8.4.1] D Metbo_0351 methyl-coenzyme M reductase I operon protein C K03421 mcrC; methyl-coenzyme M reductase subunit C D Metbo_0350 methyl-coenzyme M reductase operon protein D K03422 mcrD; methyl-coenzyme M reductase subunit D D Metbo_2279 methyl-coenzyme M reductase operon protein D K03422 mcrD; methyl-coenzyme M reductase subunit D D Metbo_1205 methyl-viologen-reducing hydrogenase delta subunit K22480 hdrA1; heterodisulfide reductase subunit A1 [EC:1.8.7.3] D Metbo_2477 methyl-viologen-reducing hydrogenase delta subunit K22480 hdrA1; heterodisulfide reductase subunit A1 [EC:1.8.7.3] D Metbo_1206 CoB--CoM heterodisulfide reductase K22481 hdrB1; heterodisulfide reductase subunit B1 [EC:1.8.7.3] D Metbo_2478 CoB--CoM heterodisulfide reductase K22481 hdrB1; heterodisulfide reductase subunit B1 [EC:1.8.7.3] D Metbo_1249 CoB--CoM heterodisulfide reductase K22481 hdrB1; heterodisulfide reductase subunit B1 [EC:1.8.7.3] D Metbo_1207 Heterodisulfide reductase subunit C, HdrC2 K22482 hdrC1; heterodisulfide reductase subunit C1 [EC:1.8.7.3] D Metbo_2479 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein K22482 hdrC1; heterodisulfide reductase subunit C1 [EC:1.8.7.3] D Metbo_0164 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein K03388 hdrA2; heterodisulfide reductase subunit A2 [EC:1.8.7.3 1.8.98.4 1.8.98.5 1.8.98.6] D Metbo_0701 CoB/CoM heterodisulfide reductase, subunit B K03389 hdrB2; heterodisulfide reductase subunit B2 [EC:1.8.7.3 1.8.98.4 1.8.98.5 1.8.98.6] D Metbo_0700 CoB/CoM heterodisulfide reductase, subunit C K03390 hdrC2; heterodisulfide reductase subunit C2 [EC:1.8.7.3 1.8.98.4 1.8.98.5 1.8.98.6] D Metbo_0368 methyl-viologen-reducing hydrogenase delta subunit K14127 mvhD; F420-non-reducing hydrogenase iron-sulfur subunit [EC:1.12.99.- 1.8.98.5 1.8.98.6] D Metbo_0370 Hydrogen dehydrogenase K14126 mvhA; F420-non-reducing hydrogenase large subunit [EC:1.12.99.- 1.8.98.5] D Metbo_0639 Hydrogen dehydrogenase K14126 mvhA; F420-non-reducing hydrogenase large subunit [EC:1.12.99.- 1.8.98.5] D Metbo_0369 NADH ubiquinone oxidoreductase 20 kDa subunit K14128 mvhG; F420-non-reducing hydrogenase small subunit [EC:1.12.99.- 1.8.98.5] D Metbo_0640 NADH ubiquinone oxidoreductase 20 kDa subunit K14128 mvhG; F420-non-reducing hydrogenase small subunit [EC:1.12.99.- 1.8.98.5] D Metbo_1898 acetate/CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D Metbo_1715 acetate/CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D Metbo_2455 Butyrate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D Metbo_0567 acetate/CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D Metbo_0488 Pyruvate synthase K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1] D Metbo_0487 Pyruvate synthase K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1] D Metbo_0490 pyruvate/ketoisovalerate oxidoreductase, gamma subunit K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1] D Metbo_0489 pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1] D Metbo_0380 phosphoenolpyruvate synthase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2] D Metbo_1172 proposed homoserine kinase K15635 apgM; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12] D Metbo_2291 phosphonopyruvate decarboxylase-related protein K15635 apgM; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12] D Metbo_0422 D-3-phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399] D Metbo_2075 phosphoserine phosphatase SerB K01079 serB; phosphoserine phosphatase [EC:3.1.3.3] D Metbo_1025 methyltransferase MtaA/CmuA family K14080 mtaA; [methyl-Co(III) methanol/glycine betaine-specific corrinoid protein]:coenzyme M methyltransferase [EC:2.1.1.246 2.1.1.377] D Metbo_1023 methanol:cobalamin methyltransferase, MtaB K04480 mtaB; methanol---5-hydroxybenzimidazolylcobamide Co-methyltransferase [EC:2.1.1.90] D Metbo_1022 cobalamin B12-binding domain protein K14081 mtaC; methanol corrinoid protein D Metbo_2244 phosphosulfolactate synthase K08097 comA; phosphosulfolactate synthase [EC:4.4.1.19] D Metbo_0343 2-phosphosulfolactate phosphatase K05979 comB; 2-phosphosulfolactate phosphatase [EC:3.1.3.71] D Metbo_0320 Malate dehydrogenase (NADP(+)) K05884 comC; L-2-hydroxycarboxylate dehydrogenase (NAD+) [EC:1.1.1.337] D Metbo_0319 sulfopyruvate decarboxylase, alpha subunit K06034 comD; sulfopyruvate decarboxylase subunit alpha [EC:4.1.1.79] D Metbo_0318 sulfopyruvate decarboxylase, beta subunit K13039 comE; sulfopyruvate decarboxylase subunit beta [EC:4.1.1.79] D Metbo_0140 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofH subunit K11781 cofH; 5-amino-6-(D-ribitylamino)uracil---L-tyrosine 4-hydroxyphenyl transferase [EC:2.5.1.147] D Metbo_1931 FO synthase subunit 2 K11781 cofH; 5-amino-6-(D-ribitylamino)uracil---L-tyrosine 4-hydroxyphenyl transferase [EC:2.5.1.147] D Metbo_0327 FO synthase subunit 1 K11780 cofG; 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase [EC:4.3.1.32] D Metbo_1012 2-phospho-L-lactate guanylyltransferase CofC K14941 cofC; 2-phospho-L-lactate/phosphoenolpyruvate guanylyltransferase [EC:2.7.7.68 2.7.7.105] D Metbo_2436 LPPG:FO 2-phospho-L-lactate transferase K11212 cofD; LPPG:FO 2-phospho-L-lactate transferase [EC:2.7.8.28] D Metbo_2435 F420-0:gamma-glutamyl ligase K12234 cofE; coenzyme F420-0:L-glutamate ligase / coenzyme F420-1:gamma-L-glutamate ligase [EC:6.3.2.31 6.3.2.34] D Metbo_2071 isopropylmalate/citramalate/homocitrate synthase K10977 aksA; methanogen homocitrate synthase [EC:2.3.3.14 2.3.3.-] D Metbo_2070 3-isopropylmalate dehydratase large subunit K16792 aksD; methanogen homoaconitase large subunit [EC:4.2.1.114] D Metbo_1944 3-isopropylmalate dehydratase small subunit K16793 aksE; methanogen homoaconitase small subunit [EC:4.2.1.114] D Metbo_0581 isopropylmalate/isohomocitrate dehydrogenase K10978 aksF; methanogen homoisocitrate dehydrogenase [EC:1.1.1.87 1.1.1.-] D Metbo_0381 L-tyrosine decarboxylase K18933 mfnA; tyrosine decarboxylase / aspartate 1-decarboxylase [EC:4.1.1.25 4.1.1.11] D Metbo_1949 ATP-grasp fold domain protein, DUF201-type K06914 mfnD; tyramine---L-glutamate ligase [EC:6.3.4.24] D Metbo_0982 UPF0264 protein K09733 mfnB; (5-formylfuran-3-yl)methyl phosphate synthase [EC:4.2.3.153] D Metbo_0405 aspartate/glutamate/uridylate kinase K07144 mfnE; 5-(aminomethyl)-3-furanmethanol phosphate kinase [EC:2.7.4.31] D Metbo_1948 H4MPT-linked C1 transfer pathway protein K07072 mfnF; (4-(4-[2-(gamma-L-glutamylamino)ethyl]phenoxymethyl)furan-2-yl)methanamine synthase [EC:2.5.1.131] C 00910 Nitrogen metabolism [PATH:mel00910] D Metbo_2415 nitrogenase alpha chain K02586 nifD; nitrogenase molybdenum-iron protein alpha chain [EC:1.18.6.1] D Metbo_1182 oxidoreductase/nitrogenase component 1 K02586 nifD; nitrogenase molybdenum-iron protein alpha chain [EC:1.18.6.1] D Metbo_1818 nitrogenase iron-iron protein, alpha chain K02586 nifD; nitrogenase molybdenum-iron protein alpha chain [EC:1.18.6.1] D Metbo_1816 oxidoreductase/nitrogenase component 1 K02591 nifK; nitrogenase molybdenum-iron protein beta chain [EC:1.18.6.1] D Metbo_1181 oxidoreductase/nitrogenase component 1 K02591 nifK; nitrogenase molybdenum-iron protein beta chain [EC:1.18.6.1] D Metbo_2414 Nitrogenase K02591 nifK; nitrogenase molybdenum-iron protein beta chain [EC:1.18.6.1] D Metbo_1819 Nitrogenase iron protein K02588 nifH; nitrogenase iron protein NifH D Metbo_1180 Nitrogenase K02588 nifH; nitrogenase iron protein NifH D Metbo_1817 Fe-only nitrogenase, delta subunit K00531 anfG; nitrogenase delta subunit [EC:1.18.6.1] D Metbo_2139 Hydroxylamine reductase K05601 hcp; hydroxylamine reductase [EC:1.7.99.1] D Metbo_0994 hybrid cluster protein K05601 hcp; hydroxylamine reductase [EC:1.7.99.1] D Metbo_2484 glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2] D Metbo_1856 Glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D Metbo_1053 carbamate kinase K00926 arcC; carbamate kinase [EC:2.7.2.2] C 00920 Sulfur metabolism [PATH:mel00920] D Metbo_1662 aliphatic sulfonates family ABC transporter, periplasmic ligand-binding protein K15553 ssuA; sulfonate transport system substrate-binding protein D Metbo_1889 ABC-type transporter, periplasmic subunit family 3 K15553 ssuA; sulfonate transport system substrate-binding protein D Metbo_1661 ABC-type transporter, integral membrane subunit K15554 ssuC; sulfonate transport system permease protein D Metbo_1660 Taurine-transporting ATPase K15555 ssuB; sulfonate transport system ATP-binding protein [EC:7.6.2.14] D Metbo_1178 serine O-acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30] D Metbo_1179 cysteine synthase A K01738 cysK; cysteine synthase [EC:2.5.1.47] D Metbo_1213 Homoserine O-acetyltransferase K00641 metX; homoserine O-acetyltransferase/O-succinyltransferase [EC:2.3.1.31 2.3.1.46] B B 09103 Lipid metabolism C 00061 Fatty acid biosynthesis [PATH:mel00061] D Metbo_0278 Long-chain-fatty-acid--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] C 00062 Fatty acid elongation C 00071 Fatty acid degradation [PATH:mel00071] D Metbo_1377 Propanoyl-CoA C-acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Metbo_0278 Long-chain-fatty-acid--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] C 00073 Cutin, suberine and wax biosynthesis C 00100 Steroid biosynthesis C 00120 Primary bile acid biosynthesis C 00121 Secondary bile acid biosynthesis C 00140 Steroid hormone biosynthesis C 00561 Glycerolipid metabolism C 00564 Glycerophospholipid metabolism [PATH:mel00564] D Metbo_2428 Phosphatidylserine decarboxylase proenzyme K01613 psd; phosphatidylserine decarboxylase [EC:4.1.1.65] D Metbo_1015 3-dehydroquinate synthase K00096 araM; glycerol-1-phosphate dehydrogenase [NAD(P)+] [EC:1.1.1.261] D Metbo_2269 Geranylgeranylglyceryl phosphate synthase K17104 E2.5.1.41; phosphoglycerol geranylgeranyltransferase [EC:2.5.1.41] D Metbo_1685 Geranylgeranylglycerol-phosphate geranylgeranyltransferase K17105 E2.5.1.42; geranylgeranylglycerol-phosphate geranylgeranyltransferase [EC:2.5.1.42] D Metbo_0516 Digeranylgeranylglyceryl phosphate synthase K17105 E2.5.1.42; geranylgeranylglycerol-phosphate geranylgeranyltransferase [EC:2.5.1.42] D Metbo_1947 UPF0290 protein K19664 carS; CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase [EC:2.7.7.67] D Metbo_2427 CDP-diacylglycerol/serine O-phosphatidyltransferase K19665 pssA; archaetidylserine synthase [EC:2.7.8.38] D Metbo_2033 Digeranylgeranylglycerophospholipid reductase K17830 GGR; digeranylgeranylglycerophospholipid reductase [EC:1.3.1.101 1.3.7.11] D Metbo_0471 Digeranylgeranylglycerophospholipid reductase K17830 GGR; digeranylgeranylglycerophospholipid reductase [EC:1.3.1.101 1.3.7.11] D Metbo_2366 geranylgeranyl reductase K17830 GGR; digeranylgeranylglycerophospholipid reductase [EC:1.3.1.101 1.3.7.11] C 00565 Ether lipid metabolism C 00600 Sphingolipid metabolism C 00590 Arachidonic acid metabolism C 00591 Linoleic acid metabolism C 00592 alpha-Linolenic acid metabolism C 01040 Biosynthesis of unsaturated fatty acids B B 09104 Nucleotide metabolism C 00230 Purine metabolism [PATH:mel00230] D Metbo_2461 Phosphoglucosamine mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2] D Metbo_2203 ribose-phosphate pyrophosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1] D Metbo_2098 amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14] D Metbo_0091 Phosphoribosylamine--glycine ligase K01945 purD; phosphoribosylamine---glycine ligase [EC:6.3.4.13] D Metbo_0153 Phosphoribosylformylglycinamidine synthase 2 K23269 purL; phosphoribosylformylglycinamidine synthase subunit PurL [EC:6.3.5.3] D Metbo_2115 phosphoribosylformylglycinamidine synthase, purS K23264 purS; phosphoribosylformylglycinamidine synthase subunit PurS [EC:6.3.5.3] D Metbo_2116 Phosphoribosylformylglycinamidine synthase 1 K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2] D Metbo_0321 phosphoribosylformylglycinamidine cyclo-ligase K01933 purM; phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.3.1] D Metbo_0177 phosphoribosylaminoimidazole carboxylase, catalytic subunit K01588 purE; 5-(carboxyamino)imidazole ribonucleotide mutase [EC:5.4.99.18] D Metbo_2114 Phosphoribosylaminoimidazole-succinocarboxamide synthase K01923 purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:6.3.2.6] D Metbo_0001 adenylosuccinate lyase K01756 purB; adenylosuccinate lyase [EC:4.3.2.2] D Metbo_0324 5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase K06863 purP; 5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase [EC:6.3.4.23] D Metbo_2434 IMP cyclohydrolase K11176 purO; IMP cyclohydrolase [EC:3.5.4.10] D Metbo_0197 phosphoribosyltransferase K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7] D Metbo_0096 Multifunctional protein surE K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6] D Metbo_2524 PfkB domain protein K22026 K22026; nucleoside kinase [EC:2.7.1.73 2.7.1.213 2.7.1.-] D Metbo_0983 inosine-5'-monophosphate dehydrogenase K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205] D Metbo_0608 Nucleoside diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6] D Metbo_0718 UPF0244 protein yjjX K01529 yjjX; inosine/xanthosine triphosphatase [EC:3.6.1.73] D Metbo_0102 non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family K01519 rdgB; XTP/dITP diphosphohydrolase [EC:3.6.1.66] D Metbo_2355 GMP synthase (glutamine-hydrolyzing) subunit A K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] D Metbo_2358 GMP synthase, large subunit K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] D Metbo_2531 anaerobic ribonucleoside-triphosphate reductase K21636 nrdD; ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6] D Metbo_1541 deoxyguanosinetriphosphate triphosphohydrolase K01129 dgt; dGTPase [EC:3.1.5.1] D Metbo_1586 Ppx/GppA phosphatase K01524 ppx-gppA; exopolyphosphatase / guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase [EC:3.6.1.11 3.6.1.40] D Metbo_1118 RelA/SpoT domain protein K07816 E2.7.6.5; GTP pyrophosphokinase [EC:2.7.6.5] D Metbo_2072 adenylyl cyclase CyaB K05873 cyaB; adenylate cyclase, class 2 [EC:4.6.1.1] D Metbo_0831 adenylosuccinate synthetase K01939 purA; adenylosuccinate synthase [EC:6.3.4.4] D Metbo_2351 Adenine deaminase K01486 ade; adenine deaminase [EC:3.5.4.2] D Metbo_2041 adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3] D Metbo_0799 Adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3] D Metbo_0537 adenylate kinase K18532 AK6; adenylate kinase [EC:2.7.4.3] D Metbo_0964 metallophosphoesterase K03651 cpdA; 3',5'-cyclic-AMP phosphodiesterase [EC:3.1.4.53] D Metbo_1053 carbamate kinase K00926 arcC; carbamate kinase [EC:2.7.2.2] C 00240 Pyrimidine metabolism [PATH:mel00240] D Metbo_2228 carbamoyl-phosphate synthase, large subunit K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5] D Metbo_2227 carbamoyl-phosphate synthase, small subunit K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5] D Metbo_0109 Aspartate carbamoyltransferase K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2] D Metbo_0952 Aspartate carbamoyltransferase regulatory chain K00610 pyrI; aspartate carbamoyltransferase regulatory subunit D Metbo_0373 dihydroorotase, multifunctional complex type K01465 URA4; dihydroorotase [EC:3.5.2.3] D Metbo_0307 dihydroorotate dehydrogenase family protein K17828 pyrDI; dihydroorotate dehydrogenase (NAD+) catalytic subunit [EC:1.3.1.14] D Metbo_0308 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulfur cluster binding domain protein K02823 pyrDII; dihydroorotate dehydrogenase electron transfer subunit D Metbo_0679 orotate phosphoribosyltransferase K00762 pyrE; orotate phosphoribosyltransferase [EC:2.4.2.10] D Metbo_1974 orotidine 5'-phosphate decarboxylase K01591 pyrF; orotidine-5'-phosphate decarboxylase [EC:4.1.1.23] D Metbo_2338 uridylate kinase K09903 pyrH; uridylate kinase [EC:2.7.4.22] D Metbo_0608 Nucleoside diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6] D Metbo_1169 CTP synthase K01937 pyrG; CTP synthase [EC:6.3.4.2] D Metbo_0802 Cytidylate kinase K00945 cmk; CMP/dCMP kinase [EC:2.7.4.25] D Metbo_0096 Multifunctional protein surE K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6] D Metbo_0383 uracil phosphoribosyltransferase K00761 upp; uracil phosphoribosyltransferase [EC:2.4.2.9] D Metbo_2524 PfkB domain protein K22026 K22026; nucleoside kinase [EC:2.7.1.73 2.7.1.213 2.7.1.-] D Metbo_0390 Cytosine deaminase K03365 FCY1; cytosine/creatinine deaminase [EC:3.5.4.1 3.5.4.21] D Metbo_2531 anaerobic ribonucleoside-triphosphate reductase K21636 nrdD; ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6] D Metbo_0662 Deoxycytidine triphosphate deaminase K01494 dcd; dCTP deaminase [EC:3.5.4.13] D Metbo_0520 Thymidylate kinase K00943 tmk; dTMP kinase [EC:2.7.4.9] D Metbo_0524 Thymidylate kinase K00943 tmk; dTMP kinase [EC:2.7.4.9] D Metbo_0551 dUTP diphosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23] D Metbo_2196 thymidylate synthase, methanogen type K00560 thyA; thymidylate synthase [EC:2.1.1.45] D Metbo_0985 thymidylate synthase, methanogen type K00560 thyA; thymidylate synthase [EC:2.1.1.45] B B 09105 Amino acid metabolism C 00250 Alanine, aspartate and glutamate metabolism [PATH:mel00250] D Metbo_0713 Aspartate transaminase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D Metbo_1176 asparagine synthase (glutamine-hydrolyzing) K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4] D Metbo_0846 asparagine synthase K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4] D Metbo_1881 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase K13566 NIT2; omega-amidase [EC:3.5.1.3] D Metbo_1835 aspartate 4-decarboxylase K09758 asdA; aspartate 4-decarboxylase [EC:4.1.1.12] D Metbo_0051 alanine dehydrogenase K19244 ala; alanine dehydrogenase [EC:1.4.1.1] D Metbo_2111 Aspartate ammonia-lyase K01744 aspA; aspartate ammonia-lyase [EC:4.3.1.1] D Metbo_0256 Argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5] D Metbo_0597 Argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1] D Metbo_0831 adenylosuccinate synthetase K01939 purA; adenylosuccinate synthase [EC:6.3.4.4] D Metbo_0001 adenylosuccinate lyase K01756 purB; adenylosuccinate lyase [EC:4.3.2.2] D Metbo_0109 Aspartate carbamoyltransferase K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2] D Metbo_0952 Aspartate carbamoyltransferase regulatory chain K00610 pyrI; aspartate carbamoyltransferase regulatory subunit D Metbo_1424 glutamate decarboxylase K01580 E4.1.1.15; glutamate decarboxylase [EC:4.1.1.15] D Metbo_1654 glutamate decarboxylase K01580 E4.1.1.15; glutamate decarboxylase [EC:4.1.1.15] D Metbo_2484 glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2] D Metbo_1856 Glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D Metbo_2228 carbamoyl-phosphate synthase, large subunit K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5] D Metbo_2227 carbamoyl-phosphate synthase, small subunit K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5] D Metbo_2116 Phosphoribosylformylglycinamidine synthase 1 K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2] D Metbo_2109 Glucosamine--fructose-6-phosphate aminotransferase (isomerizing) K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] D Metbo_1749 Glutamine--fructose-6-phosphate transaminase (isomerizing) K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] D Metbo_2098 amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14] C 00260 Glycine, serine and threonine metabolism [PATH:mel00260] D Metbo_1907 aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4] D Metbo_1904 aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11] D Metbo_1173 Homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3] D Metbo_0288 homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3] D Metbo_0613 threonine synthase K01733 thrC; threonine synthase [EC:4.2.3.1] D Metbo_0162 Glycine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D Metbo_1243 Glycine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D Metbo_1172 proposed homoserine kinase K15635 apgM; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12] D Metbo_2291 phosphonopyruvate decarboxylase-related protein K15635 apgM; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12] D Metbo_0422 D-3-phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399] D Metbo_2075 phosphoserine phosphatase SerB K01079 serB; phosphoserine phosphatase [EC:3.1.3.3] D Metbo_2051 Dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Metbo_2043 Tryptophan synthase alpha chain K01695 trpA; tryptophan synthase alpha chain [EC:4.2.1.20] D Metbo_2044 Tryptophan synthase beta chain K01696 trpB; tryptophan synthase beta chain [EC:4.2.1.20] D Metbo_0070 Tryptophan synthase beta chain K06001 trpB; tryptophan synthase beta chain [EC:4.2.1.20] C 00270 Cysteine and methionine metabolism [PATH:mel00270] D Metbo_1178 serine O-acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30] D Metbo_1179 cysteine synthase A K01738 cysK; cysteine synthase [EC:2.5.1.47] D Metbo_1268 Cystathionine gamma-lyase K01760 metC; cysteine-S-conjugate beta-lyase [EC:4.4.1.13] D Metbo_1184 Cystathionine beta-lyase K14155 patB; cysteine-S-conjugate beta-lyase [EC:4.4.1.13] D Metbo_2197 Methionine synthase vitamin-B12 independent K00549 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14] D Metbo_0155 S-adenosylmethionine synthase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6] D Metbo_0014 5-methylthioadenosine/S-adenosylhomocysteine deaminase K12960 mtaD; 5-methylthioadenosine/S-adenosylhomocysteine deaminase [EC:3.5.4.31 3.5.4.28] D Metbo_0555 methylthioadenosine phosphorylase K19696 mtiP; 5'-methylthioinosine phosphorylase [EC:2.4.2.44] D Metbo_0691 translation initiation factor, aIF-2BI family K08963 mtnA; methylthioribose-1-phosphate isomerase [EC:5.3.1.23] D Metbo_2065 Adenosylhomocysteinase K01566 E3.13.1.9; S-inosyl-L-homocysteine hydrolase [EC:3.13.1.9] D Metbo_1907 aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4] D Metbo_1904 aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11] D Metbo_1173 Homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3] D Metbo_0288 homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3] D Metbo_1965 protein of unknown function DUF39 K23975 E2.8.1.16; L-aspartate semialdehyde sulfurtransferase [EC:2.8.1.16] D Metbo_1966 NIL domain-containing protein K23976 K23976; L-aspartate semialdehyde sulfurtransferase ferredoxin D Metbo_1213 Homoserine O-acetyltransferase K00641 metX; homoserine O-acetyltransferase/O-succinyltransferase [EC:2.3.1.31 2.3.1.46] D Metbo_1212 O-acetylhomoserine/O-acetylserine sulfhydrylase K01740 metY; O-acetylhomoserine (thiol)-lyase [EC:2.5.1.49] D Metbo_0098 branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] D Metbo_1259 glutamate--cysteine ligase K01919 gshA; glutamate--cysteine ligase [EC:6.3.2.2] D Metbo_1298 glutamylcysteine synthetase K01919 gshA; glutamate--cysteine ligase [EC:6.3.2.2] D Metbo_0713 Aspartate transaminase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D Metbo_1835 aspartate 4-decarboxylase K09758 asdA; aspartate 4-decarboxylase [EC:4.1.1.12] D Metbo_0579 Malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37] D Metbo_0422 D-3-phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399] C 00280 Valine, leucine and isoleucine degradation [PATH:mel00280] D Metbo_0098 branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] D Metbo_2051 Dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Metbo_2453 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin) K00186 vorA; 2-oxoisovalerate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.7] D Metbo_2452 Pyruvate/ketoisovalerate oxidoreductase K00187 vorB; 2-oxoisovalerate ferredoxin oxidoreductase beta subunit [EC:1.2.7.7] D Metbo_2454 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein K00188 vorD; 2-oxoisovalerate ferredoxin oxidoreductase delta subunit [EC:1.2.7.7] D Metbo_1377 Propanoyl-CoA C-acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Metbo_1378 UPF0219 protein K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10] C 00290 Valine, leucine and isoleucine biosynthesis [PATH:mel00290] D Metbo_2364 isopropylmalate/citramalate/homocitrate synthase K09011 cimA; (R)-citramalate synthase [EC:2.3.3.21] D Metbo_0169 3-isopropylmalate dehydratase large subunit K01703 leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35] D Metbo_0170 3-isopropylmalate dehydratase small subunit K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35] D Metbo_0171 3-isopropylmalate dehydrogenase K00052 leuB; 3-isopropylmalate dehydrogenase [EC:1.1.1.85] D Metbo_0092 acetolactate synthase, large subunit, biosynthetic type K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D Metbo_0566 Acetolactate synthase K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D Metbo_0093 acetolactate synthase, small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6] D Metbo_0094 Ketol-acid reductoisomerase K00053 ilvC; ketol-acid reductoisomerase [EC:1.1.1.86] D Metbo_0087 Dihydroxy-acid dehydratase K01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9] D Metbo_0098 branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] D Metbo_0066 isopropylmalate/citramalate/homocitrate synthase K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13] C 00300 Lysine biosynthesis [PATH:mel00300] D Metbo_1173 Homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3] D Metbo_0288 homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3] D Metbo_1907 aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4] D Metbo_1904 aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11] D Metbo_1906 Dihydrodipicolinate synthase K01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7] D Metbo_1905 Dihydrodipicolinate reductase K00215 dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8] D Metbo_0120 Acetylornithine/succinyldiaminopimelate aminotransferase K00821 argD; acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17] D Metbo_0118 Diaminopimelate epimerase K01778 dapF; diaminopimelate epimerase [EC:5.1.1.7] D Metbo_0824 LL-diaminopimelate aminotransferase K10206 E2.6.1.83; LL-diaminopimelate aminotransferase [EC:2.6.1.83] D Metbo_0119 diaminopimelate decarboxylase K01586 lysA; diaminopimelate decarboxylase [EC:4.1.1.20] D Metbo_2071 isopropylmalate/citramalate/homocitrate synthase K10977 aksA; methanogen homocitrate synthase [EC:2.3.3.14 2.3.3.-] D Metbo_2070 3-isopropylmalate dehydratase large subunit K16792 aksD; methanogen homoaconitase large subunit [EC:4.2.1.114] D Metbo_1944 3-isopropylmalate dehydratase small subunit K16793 aksE; methanogen homoaconitase small subunit [EC:4.2.1.114] D Metbo_0581 isopropylmalate/isohomocitrate dehydrogenase K10978 aksF; methanogen homoisocitrate dehydrogenase [EC:1.1.1.87 1.1.1.-] D Metbo_0711 putative transcriptional regulator, GntR family K05825 LYSN; 2-aminoadipate transaminase [EC:2.6.1.-] D Metbo_2215 Mur ligase middle domain protein K01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13] C 00310 Lysine degradation [PATH:mel00310] D Metbo_2051 Dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Metbo_1377 Propanoyl-CoA C-acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] C 00220 Arginine biosynthesis [PATH:mel00220] D Metbo_0090 Ornithine carbamoyltransferase K00611 OTC; ornithine carbamoyltransferase [EC:2.1.3.3] D Metbo_0256 Argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5] D Metbo_0597 Argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1] D Metbo_2116 Phosphoribosylformylglycinamidine synthase 1 K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2] D Metbo_2484 glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2] D Metbo_1856 Glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D Metbo_2228 carbamoyl-phosphate synthase, large subunit K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5] D Metbo_2227 carbamoyl-phosphate synthase, small subunit K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5] D Metbo_1053 carbamate kinase K00926 arcC; carbamate kinase [EC:2.7.2.2] D Metbo_0713 Aspartate transaminase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D Metbo_0960 Arginine biosynthesis bifunctional protein ArgJ K00620 argJ; glutamate N-acetyltransferase / amino-acid N-acetyltransferase [EC:2.3.1.35 2.3.1.1] D Metbo_0959 acetylglutamate kinase K00930 argB; acetylglutamate kinase [EC:2.7.2.8] D Metbo_0957 N-acetyl-gamma-glutamyl-phosphate reductase K00145 argC; N-acetyl-gamma-glutamyl-phosphate reductase [EC:1.2.1.38] D Metbo_0120 Acetylornithine/succinyldiaminopimelate aminotransferase K00821 argD; acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17] C 00330 Arginine and proline metabolism [PATH:mel00330] D Metbo_0390 Cytosine deaminase K03365 FCY1; cytosine/creatinine deaminase [EC:3.5.4.1 3.5.4.21] D Metbo_2346 arginine decarboxylase, pyruvoyl-dependent K02626 pdaD; arginine decarboxylase [EC:4.1.1.19] D Metbo_2349 agmatinase K01480 speB; agmatinase [EC:3.5.3.11] D Metbo_0126 agmatinase K01480 speB; agmatinase [EC:3.5.3.11] D Metbo_0713 Aspartate transaminase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] C 00340 Histidine metabolism [PATH:mel00340] D Metbo_0015 ATP phosphoribosyltransferase K00765 hisG; ATP phosphoribosyltransferase [EC:2.4.2.17] D Metbo_0316 Phosphoribosyl-ATP pyrophosphatase K01523 hisE; phosphoribosyl-ATP pyrophosphohydrolase [EC:3.6.1.31] D Metbo_0621 Phosphoribosyl-AMP cyclohydrolase K01496 hisI; phosphoribosyl-AMP cyclohydrolase [EC:3.5.4.19] D Metbo_1954 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino) imidazole-4-carboxamide isomerase K01814 hisA; phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase [EC:5.3.1.16] D Metbo_2177 histidine biosynthesis protein K01814 hisA; phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase [EC:5.3.1.16] D Metbo_0039 Imidazole glycerol phosphate synthase subunit hisH K02501 hisH; imidazole glycerol-phosphate synthase subunit HisH [EC:4.3.2.10] D Metbo_0131 Imidazole glycerol phosphate synthase subunit hisF K02500 hisF; imidazole glycerol-phosphate synthase subunit HisF [EC:4.3.2.10] D Metbo_0077 Imidazoleglycerol-phosphate dehydratase K01693 hisB; imidazoleglycerol-phosphate dehydratase [EC:4.2.1.19] D Metbo_2295 Histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] D Metbo_1367 Histidinol dehydrogenase K00013 hisD; histidinol dehydrogenase [EC:1.1.1.23] C 00350 Tyrosine metabolism [PATH:mel00350] D Metbo_0713 Aspartate transaminase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D Metbo_2295 Histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] D Metbo_0381 L-tyrosine decarboxylase K18933 mfnA; tyrosine decarboxylase / aspartate 1-decarboxylase [EC:4.1.1.25 4.1.1.11] C 00360 Phenylalanine metabolism [PATH:mel00360] D Metbo_1008 Phenylacetate--CoA ligase K01912 paaK; phenylacetate-CoA ligase [EC:6.2.1.30] D Metbo_0669 Phenylacetate--CoA ligase K01912 paaK; phenylacetate-CoA ligase [EC:6.2.1.30] D Metbo_1399 phenylacetic acid degradation-related protein K02614 paaI; acyl-CoA thioesterase [EC:3.1.2.-] D Metbo_0713 Aspartate transaminase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D Metbo_2295 Histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] C 00380 Tryptophan metabolism [PATH:mel00380] D Metbo_2051 Dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Metbo_1377 Propanoyl-CoA C-acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] C 00400 Phenylalanine, tyrosine and tryptophan biosynthesis [PATH:mel00400] D Metbo_1361 phospho-2-dehydro-3-deoxyheptonate aldolase K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10] D Metbo_1360 3-dehydroquinate synthase K11646 K11646; 3-dehydroquinate synthase II [EC:1.4.1.24] D Metbo_0630 3-dehydroquinate dehydratase K03785 aroD; 3-dehydroquinate dehydratase I [EC:4.2.1.10] D Metbo_0624 Shikimate dehydrogenase K00014 aroE; shikimate dehydrogenase [EC:1.1.1.25] D Metbo_1910 Shikimate kinase K00891 aroK; shikimate kinase [EC:2.7.1.71] D Metbo_0942 3-phosphoshikimate 1-carboxyvinyltransferase K00800 aroA; 3-phosphoshikimate 1-carboxyvinyltransferase [EC:2.5.1.19] D Metbo_1088 chorismate synthase K01736 aroC; chorismate synthase [EC:4.2.3.5] D Metbo_2048 anthranilate synthase component I K01657 trpE; anthranilate synthase component I [EC:4.1.3.27] D Metbo_2047 glutamine amidotransferase of anthranilate synthase K01658 trpG; anthranilate synthase component II [EC:4.1.3.27] D Metbo_2042 Anthranilate phosphoribosyltransferase K00766 trpD; anthranilate phosphoribosyltransferase [EC:2.4.2.18] D Metbo_2045 N-(5'phosphoribosyl)anthranilate isomerase (PRAI) K01817 trpF; phosphoribosylanthranilate isomerase [EC:5.3.1.24] D Metbo_2043 Tryptophan synthase alpha chain K01695 trpA; tryptophan synthase alpha chain [EC:4.2.1.20] D Metbo_2044 Tryptophan synthase beta chain K01696 trpB; tryptophan synthase beta chain [EC:4.2.1.20] D Metbo_0070 Tryptophan synthase beta chain K06001 trpB; tryptophan synthase beta chain [EC:4.2.1.20] D Metbo_1909 chorismate mutase K04093 pheA1; chorismate mutase [EC:5.4.99.5] D Metbo_2063 Prephenate dehydrogenase K04517 tyrA2; prephenate dehydrogenase [EC:1.3.1.12] D Metbo_0300 Prephenate dehydratase K04518 pheA2; prephenate dehydratase [EC:4.2.1.51] D Metbo_0713 Aspartate transaminase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D Metbo_2295 Histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] B B 09106 Metabolism of other amino acids C 00410 beta-Alanine metabolism [PATH:mel00410] D Metbo_0381 L-tyrosine decarboxylase K18933 mfnA; tyrosine decarboxylase / aspartate 1-decarboxylase [EC:4.1.1.25 4.1.1.11] D Metbo_1424 glutamate decarboxylase K01580 E4.1.1.15; glutamate decarboxylase [EC:4.1.1.15] D Metbo_1654 glutamate decarboxylase K01580 E4.1.1.15; glutamate decarboxylase [EC:4.1.1.15] D Metbo_1164 protein of unknown function DUF137 K09722 K09722; 4-phosphopantoate---beta-alanine ligase [EC:6.3.2.36] C 00430 Taurine and hypotaurine metabolism [PATH:mel00430] D Metbo_1424 glutamate decarboxylase K01580 E4.1.1.15; glutamate decarboxylase [EC:4.1.1.15] D Metbo_1654 glutamate decarboxylase K01580 E4.1.1.15; glutamate decarboxylase [EC:4.1.1.15] D Metbo_0051 alanine dehydrogenase K19244 ala; alanine dehydrogenase [EC:1.4.1.1] C 00440 Phosphonate and phosphinate metabolism C 00450 Selenocompound metabolism [PATH:mel00450] D Metbo_1268 Cystathionine gamma-lyase K01760 metC; cysteine-S-conjugate beta-lyase [EC:4.4.1.13] D Metbo_1184 Cystathionine beta-lyase K14155 patB; cysteine-S-conjugate beta-lyase [EC:4.4.1.13] D Metbo_2197 Methionine synthase vitamin-B12 independent K00549 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14] D Metbo_0172 Cysteine desulfurase K11717 sufS; cysteine desulfurase / selenocysteine lyase [EC:2.8.1.7 4.4.1.16] D Metbo_2446 Thioredoxin-disulfide reductase K00384 trxB; thioredoxin reductase (NADPH) [EC:1.8.1.9] D Metbo_0760 pyridoxal phosphate enzyme K01042 selA; L-seryl-tRNA(Ser) seleniumtransferase [EC:2.9.1.1] D Metbo_1344 Methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] C 00460 Cyanoamino acid metabolism D Metbo_0162 Glycine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D Metbo_1243 Glycine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] C 00470 D-Amino acid metabolism [PATH:mel00470] D Metbo_2116 Phosphoribosylformylglycinamidine synthase 1 K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2] D Metbo_2264 UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9] D Metbo_0118 Diaminopimelate epimerase K01778 dapF; diaminopimelate epimerase [EC:5.1.1.7] D Metbo_0119 diaminopimelate decarboxylase K01586 lysA; diaminopimelate decarboxylase [EC:4.1.1.20] C 00480 Glutathione metabolism D Metbo_1259 glutamate--cysteine ligase K01919 gshA; glutamate--cysteine ligase [EC:6.3.2.2] D Metbo_1298 glutamylcysteine synthetase K01919 gshA; glutamate--cysteine ligase [EC:6.3.2.2] B B 09107 Glycan biosynthesis and metabolism C 00510 N-Glycan biosynthesis C 00513 Various types of N-glycan biosynthesis C 00512 Mucin type O-glycan biosynthesis C 00515 Mannose type O-glycan biosynthesis C 00514 Other types of O-glycan biosynthesis C 00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate C 00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin C 00533 Glycosaminoglycan biosynthesis - keratan sulfate C 00531 Glycosaminoglycan degradation C 00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis C 00601 Glycosphingolipid biosynthesis - lacto and neolacto series C 00603 Glycosphingolipid biosynthesis - globo and isoglobo series C 00604 Glycosphingolipid biosynthesis - ganglio series C 00511 Other glycan degradation C 00540 Lipopolysaccharide biosynthesis C 00542 O-Antigen repeat unit biosynthesis C 00541 O-Antigen nucleotide sugar biosynthesis C 00550 Peptidoglycan biosynthesis C 00552 Teichoic acid biosynthesis [PATH:mel00552] D Metbo_0099 Undecaprenyl-diphosphatase K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27] D Metbo_0878 Undecaprenyl-diphosphatase K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27] C 00571 Lipoarabinomannan (LAM) biosynthesis C 00572 Arabinogalactan biosynthesis - Mycobacterium C 00543 Exopolysaccharide biosynthesis [PATH:mel00543] D Metbo_0862 polysaccharide pyruvyl transferase K16710 wcaK; colanic acid/amylovoran biosynthesis protein WcaK/AmsJ D Metbo_1178 serine O-acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30] B B 09108 Metabolism of cofactors and vitamins C 00730 Thiamine metabolism [PATH:mel00730] D Metbo_2467 Phosphomethylpyrimidine synthase K03147 thiC; phosphomethylpyrimidine synthase [EC:4.1.99.17] D Metbo_2525 Phosphomethylpyrimidine synthase K03147 thiC; phosphomethylpyrimidine synthase [EC:4.1.99.17] D Metbo_1011 phosphomethylpyrimidine kinase K00941 thiD; hydroxymethylpyrimidine/phosphomethylpyrimidine kinase [EC:2.7.1.49 2.7.4.7] D Metbo_1214 Cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D Metbo_1848 Cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D Metbo_1266 tRNA sulfurtransferase K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4] D Metbo_0536 thiazole biosynthetic enzyme K22699 thi4; sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] D Metbo_1265 thiazole biosynthetic enzyme K22699 thi4; sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] D Metbo_1959 Phosphomethylpyrimidine kinase K21220 thiN; thiamine-phosphate diphosphorylase [EC:2.5.1.3] D Metbo_0180 thiamine-monophosphate kinase K00946 thiL; thiamine-monophosphate kinase [EC:2.7.4.16] D Metbo_2041 adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3] D Metbo_0799 Adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3] C 00740 Riboflavin metabolism [PATH:mel00740] D Metbo_2437 GTP cyclohydrolase III K08096 gch3; GTP cyclohydrolase IIa [EC:3.5.4.29] D Metbo_2103 Creatininase K14653 arfB; 2-amino-5-formylamino-6-ribosylaminopyrimidin-4(3H)-one 5'-monophosphate deformylase [EC:3.5.1.102] D Metbo_0239 5-amino-6-(5-phosphoribosylamino) uracil reductase K14654 RIB7; 2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase [EC:1.1.1.302] D Metbo_2125 Riboflavin-specific deaminase domain protein K14654 RIB7; 2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase [EC:1.1.1.302] D Metbo_0046 3,4-dihydroxy-2-butanone 4-phosphate synthase K02858 ribB; 3,4-dihydroxy 2-butanone 4-phosphate synthase [EC:4.1.99.12] D Metbo_0173 6,7-dimethyl-8-ribityllumazine synthase K00794 ribH; 6,7-dimethyl-8-ribityllumazine synthase [EC:2.5.1.78] D Metbo_2194 riboflavin synthase K00793 ribE; riboflavin synthase [EC:2.5.1.9] D Metbo_0045 protein of unknown function DUF120 K07732 rfk; riboflavin kinase, archaea type [EC:2.7.1.161] D Metbo_1957 cytidyltransferase-related domain protein K14656 ribL; FAD synthetase [EC:2.7.7.2] D Metbo_0989 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129] C 00750 Vitamin B6 metabolism [PATH:mel00750] D Metbo_0613 threonine synthase K01733 thrC; threonine synthase [EC:4.2.3.1] D Metbo_1263 Pyridoxal biosynthesis lyase pdxS K06215 pdxS; pyridoxal 5'-phosphate synthase pdxS subunit [EC:4.3.3.6] D Metbo_0577 Glutamine amidotransferase subunit pdxT K08681 pdxT; pyridoxal 5'-phosphate synthase pdxT subunit [EC:4.3.3.6] C 00760 Nicotinate and nicotinamide metabolism [PATH:mel00760] D Metbo_0419 L-aspartate dehydrogenase K06989 nadX; aspartate dehydrogenase [EC:1.4.1.21] D Metbo_0554 Quinolinate synthase A K03517 nadA; quinolinate synthase [EC:2.5.1.72] D Metbo_0646 nicotinate-nucleotide pyrophosphorylase K00767 nadC; nicotinate-nucleotide pyrophosphorylase (carboxylating) [EC:2.4.2.19] D Metbo_0096 Multifunctional protein surE K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6] D Metbo_0992 Nicotinamide-nucleotide adenylyltransferase K00952 nadM; nicotinamide-nucleotide adenylyltransferase [EC:2.7.7.1] D Metbo_1705 NAD(+) diphosphatase K03426 NUDT12_13; NAD+ diphosphatase [EC:3.6.1.22] D Metbo_0019 NH(3)-dependent NAD(+) synthetase K01916 nadE; NAD+ synthase [EC:6.3.1.5] D Metbo_2344 inorganic polyphosphate/ATP-NAD kinase K00858 ppnK; NAD+ kinase [EC:2.7.1.23] C 00770 Pantothenate and CoA biosynthesis [PATH:mel00770] D Metbo_0092 acetolactate synthase, large subunit, biosynthetic type K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D Metbo_0566 Acetolactate synthase K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D Metbo_0093 acetolactate synthase, small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6] D Metbo_0094 Ketol-acid reductoisomerase K00053 ilvC; ketol-acid reductoisomerase [EC:1.1.1.86] D Metbo_0087 Dihydroxy-acid dehydratase K01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9] D Metbo_1544 Ketopantoate reductase ApbA/PanE domain protein K00077 panE; 2-dehydropantoate 2-reductase [EC:1.1.1.169] D Metbo_2122 GHMP kinase K06982 pok; pantoate kinase [EC:2.7.1.169] D Metbo_1164 protein of unknown function DUF137 K09722 K09722; 4-phosphopantoate---beta-alanine ligase [EC:6.3.2.36] D Metbo_0304 phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase K13038 coaBC; phosphopantothenoylcysteine decarboxylase / phosphopantothenate---cysteine ligase [EC:4.1.1.36 6.3.2.5] D Metbo_0717 Phosphopantetheine adenylyltransferase K02201 E2.7.7.3B; pantetheine-phosphate adenylyltransferase [EC:2.7.7.3] D Metbo_0600 UPF0218 protein K09735 dpck; GTP-dependent dephospho-CoA kinase [EC:2.7.1.237] D Metbo_0098 branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] D Metbo_0381 L-tyrosine decarboxylase K18933 mfnA; tyrosine decarboxylase / aspartate 1-decarboxylase [EC:4.1.1.25 4.1.1.11] C 00780 Biotin metabolism [PATH:mel00780] D Metbo_0763 biotin/acetyl-CoA-carboxylase ligase K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15] C 00785 Lipoic acid metabolism [PATH:mel00785] D Metbo_2051 Dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] C 00790 Folate biosynthesis [PATH:mel00790] D Metbo_0292 6-pyruvoyltetrahydropterin synthase K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50] D Metbo_0293 Radical SAM domain protein K10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3] D Metbo_0392 exsB protein K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20] D Metbo_0329 protein of unknown function DUF198 K17488 mptA; GTP cyclohydrolase IV [EC:3.5.4.39] D Metbo_2423 protein of unknown function DUF372 K09739 mptD; dihydroneopterin aldolase [EC:4.1.2.25] D Metbo_0563 protein of unknown function DUF115 K07142 mptE; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase [EC:2.7.6.3] D Metbo_1945 beta-ribofuranosylaminobenzene 5'-phosphate synthase family K06984 K06984; beta-ribofuranosylaminobenzene 5'-phosphate synthase [EC:2.4.2.54] D Metbo_2091 beta-lactamase domain protein K06897 K06897; 7,8-dihydropterin-6-yl-methyl-4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate synthase [EC:2.5.1.105] D Metbo_0161 archaeoflavoprotein, MJ0208 family K18853 dmrX; dihydromethanopterin reductase (acceptor) [EC:1.5.99.15] D Metbo_2517 molybdenum cofactor biosynthesis protein A K03639 moaA; GTP 3',8-cyclase [EC:4.1.99.22] D Metbo_1914 molybdenum cofactor biosynthesis protein C K03637 moaC; cyclic pyranopterin monophosphate synthase [EC:4.6.1.17] D Metbo_0991 molybdopterin biosynthesis MoaE protein K03635 MOCS2B; molybdopterin synthase catalytic subunit [EC:2.8.1.12] D Metbo_0680 molybdenum cofactor synthesis domain protein K03638 moaB; molybdopterin adenylyltransferase [EC:2.7.7.75] D Metbo_0147 molybdenum cofactor synthesis domain protein K03750 moeA; molybdopterin molybdotransferase [EC:2.10.1.1] D Metbo_0984 Molybdopterin-guanine dinucleotide biosynthesis protein A K03752 mobA; molybdenum cofactor guanylyltransferase [EC:2.7.7.77] C 00670 One carbon pool by folate [PATH:mel00670] D Metbo_0162 Glycine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D Metbo_1243 Glycine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D Metbo_2196 thymidylate synthase, methanogen type K00560 thyA; thymidylate synthase [EC:2.1.1.45] D Metbo_0985 thymidylate synthase, methanogen type K00560 thyA; thymidylate synthase [EC:2.1.1.45] D Metbo_1379 5-formyltetrahydrofolate cyclo-ligase K01934 MTHFS; 5-formyltetrahydrofolate cyclo-ligase [EC:6.3.3.2] C 00830 Retinol metabolism C 00860 Porphyrin metabolism [PATH:mel00860] D Metbo_0823 glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D Metbo_2442 Glutamyl-tRNA reductase K02492 hemA; glutamyl-tRNA reductase [EC:1.2.1.70] D Metbo_2131 Glutamate-1-semialdehyde 2,1-aminomutase K01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8] D Metbo_1083 Porphobilinogen synthase K01698 hemB; porphobilinogen synthase [EC:4.2.1.24] D Metbo_2342 Porphobilinogen deaminase K01749 hemC; hydroxymethylbilane synthase [EC:2.5.1.61] D Metbo_0827 flavodoxin/nitric oxide synthase K00230 hemG; menaquinone-dependent protoporphyrinogen oxidase [EC:1.3.5.3] D Metbo_2117 uroporphyrin-III C-methyltransferase K02303 cobA; uroporphyrin-III C-methyltransferase [EC:2.1.1.107] D Metbo_2441 siroheme synthase K24866 sirC; precorrin-2 dehydrogenase [EC:1.3.1.76] D Metbo_0181 Sirohydrochlorin cobaltochelatase K22011 cfbA; sirohydrochlorin cobalto/nickelchelatase [EC:4.99.1.3 4.99.1.11] D Metbo_0135 precorrin-2 C20-methyltransferase K03394 cobI-cbiL; precorrin-2/cobalt-factor-2 C20-methyltransferase [EC:2.1.1.130 2.1.1.151] D Metbo_0117 precorrin-3B C17-methyltransferase K05934 cobJ; precorrin-3B C17-methyltransferase / cobalt-factor III methyltransferase [EC:2.1.1.131 2.1.1.272] D Metbo_0836 precorrin-4 C11-methyltransferase K05936 cobM; precorrin-4/cobalt-precorrin-4 C11-methyltransferase [EC:2.1.1.133 2.1.1.271] D Metbo_0112 cobalamin (vitamin B12) biosynthesis CbiG protein K02189 cbiG; cobalt-precorrin 5A hydrolase [EC:3.7.1.12] D Metbo_2223 precorrin-6x reductase K05895 cobK-cbiJ; precorrin-6A/cobalt-precorrin-6A reductase [EC:1.3.1.54 1.3.1.106] D Metbo_1913 cobalt-precorrin-6A synthase (deacetylating) K02188 cbiD; cobalt-precorrin-5B (C1)-methyltransferase [EC:2.1.1.195] D Metbo_0988 cobalt-precorrin-6Y C(15)-methyltransferase (decarboxylating) K02191 cbiT; cobalt-precorrin-6B (C15)-methyltransferase [EC:2.1.1.196] D Metbo_0023 precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit K03399 cbiE; cobalt-precorrin-7 (C5)-methyltransferase [EC:2.1.1.289] D Metbo_2133 Precorrin-8X methylmutase CbiC/CobH K06042 cobH-cbiC; precorrin-8X/cobalt-precorrin-8 methylmutase [EC:5.4.99.61 5.4.99.60] D Metbo_0082 Cobyrinic acid A,C-diamide synthase K02224 cobB-cbiA; cobyrinic acid a,c-diamide synthase [EC:6.3.5.9 6.3.5.11] D Metbo_2207 Cobyric acid synthase K02232 cobQ; adenosylcobyric acid synthase [EC:6.3.5.10] D Metbo_0111 Cobalamin biosynthesis protein cbiB K02227 cbiB; adenosylcobinamide-phosphate synthase [EC:6.3.1.10] D Metbo_0364 acylneuraminate cytidylyltransferase K19712 cobY; adenosylcobinamide-phosphate guanylyltransferase [EC:2.7.7.62] D Metbo_0386 Cobalamin synthase K02233 E2.7.8.26; adenosylcobinamide-GDP ribazoletransferase [EC:2.7.8.26] D Metbo_2093 Nitrogenase iron protein K21610 cfbC; Ni-sirohydrochlorin a,c-diamide reductive cyclase subunit CfbC [EC:6.3.3.7] D Metbo_0037 methanogenesis marker 13 metalloprotein K21611 cfbD; Ni-sirohydrochlorin a,c-diamide reductive cyclase subunit CfbD [EC:6.3.3.7] D Metbo_2343 Mur ligase middle domain protein K21612 cfbE; coenzyme F430 synthetase [EC:6.4.1.9] D Metbo_2273 Magnesium chelatase K03404 chlD; magnesium chelatase subunit D [EC:6.6.1.1] D Metbo_1398 hypothetical protein K03594 bfr; bacterioferritin [EC:1.16.3.1] C 00130 Ubiquinone and other terpenoid-quinone biosynthesis [PATH:mel00130] D Metbo_0989 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129] D Metbo_2001 UbiA prenyltransferase K02548 menA; 1,4-dihydroxy-2-naphthoate polyprenyltransferase [EC:2.5.1.74] D Metbo_2002 UbiA prenyltransferase K02548 menA; 1,4-dihydroxy-2-naphthoate polyprenyltransferase [EC:2.5.1.74] D Metbo_1072 hypothetical protein K09834 VTE1; tocopherol cyclase [EC:5.5.1.24] B B 09109 Metabolism of terpenoids and polyketides C 00900 Terpenoid backbone biosynthesis [PATH:mel00900] D Metbo_1377 Propanoyl-CoA C-acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Metbo_1378 UPF0219 protein K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10] D Metbo_0627 3-hydroxy-3-methylglutaryl Coenzyme A reductase K00021 HMGCR; hydroxymethylglutaryl-CoA reductase (NADPH) [EC:1.1.1.34] D Metbo_0818 mevalonate kinase K00869 MVK; mevalonate kinase [EC:2.7.1.36] D Metbo_0819 aspartate/glutamate/uridylate kinase K06981 ipk; isopentenyl phosphate kinase [EC:2.7.4.26] D Metbo_0105 protein of unknown function DUF521 K25517 acnX1; phosphomecalonate degydratase large subunit [EC:4.2.1.182] D Metbo_0003 UPF0107 protein K09128 acnX2; phosphomecalonate degydratase small subunit [EC:4.2.1.182] D Metbo_0178 UbiD family decarboxylase K25518 E4.1.1.126; anhydromevalonate phosphate decarboxylase [EC:4.1.1.126] D Metbo_0989 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129] D Metbo_0820 Isopentenyl-diphosphate delta-isomerase K01823 idi; isopentenyl-diphosphate Delta-isomerase [EC:5.3.3.2] D Metbo_0822 Dimethylallyltranstransferase K13787 idsA; geranylgeranyl diphosphate synthase, type I [EC:2.5.1.1 2.5.1.10 2.5.1.29] D Metbo_2128 Undecaprenyl pyrophosphate synthase K15888 uppS; tritrans,polycis-undecaprenyl-diphosphate synthase [geranylgeranyl-diphosphate specific] [EC:2.5.1.89] C 00902 Monoterpenoid biosynthesis C 00909 Sesquiterpenoid and triterpenoid biosynthesis C 00904 Diterpenoid biosynthesis C 00906 Carotenoid biosynthesis C 00905 Brassinosteroid biosynthesis C 00981 Insect hormone biosynthesis C 00908 Zeatin biosynthesis C 00903 Limonene degradation C 00907 Pinene, camphor and geraniol degradation C 01052 Type I polyketide structures C 00522 Biosynthesis of 12-, 14- and 16-membered macrolides C 01051 Biosynthesis of ansamycins C 01059 Biosynthesis of enediyne antibiotics C 01056 Biosynthesis of type II polyketide backbone C 01057 Biosynthesis of type II polyketide products C 00253 Tetracycline biosynthesis C 00523 Polyketide sugar unit biosynthesis [PATH:mel00523] D Metbo_0919 glucose-1-phosphate thymidylyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24] D Metbo_2293 Glucosamine-1-phosphate N-acetyltransferase K23144 K23144; UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.7.7.24 2.7.7.83 2.3.1.157 2.3.1.276] D Metbo_2085 dTDP-glucose 4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46] D Metbo_1598 UDP-glucuronate decarboxylase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46] D Metbo_0904 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13] D Metbo_0920 dTDP-4-dehydrorhamnose reductase K00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133] C 01054 Nonribosomal peptide structures C 01053 Biosynthesis of siderophore group nonribosomal peptides C 01055 Biosynthesis of vancomycin group antibiotics D Metbo_2085 dTDP-glucose 4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46] D Metbo_1598 UDP-glucuronate decarboxylase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46] B B 09110 Biosynthesis of other secondary metabolites C 00940 Phenylpropanoid biosynthesis C 00945 Stilbenoid, diarylheptanoid and gingerol biosynthesis C 00941 Flavonoid biosynthesis C 00944 Flavone and flavonol biosynthesis C 00942 Anthocyanin biosynthesis C 00943 Isoflavonoid biosynthesis C 00946 Degradation of flavonoids C 00901 Indole alkaloid biosynthesis C 00403 Indole diterpene alkaloid biosynthesis C 00950 Isoquinoline alkaloid biosynthesis C 00960 Tropane, piperidine and pyridine alkaloid biosynthesis C 00996 Biosynthesis of various alkaloids C 00232 Caffeine metabolism C 00965 Betalain biosynthesis C 00966 Glucosinolate biosynthesis C 00402 Benzoxazinoid biosynthesis C 00311 Penicillin and cephalosporin biosynthesis C 00332 Carbapenem biosynthesis C 00261 Monobactam biosynthesis [PATH:mel00261] D Metbo_1907 aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4] D Metbo_1904 aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11] D Metbo_1906 Dihydrodipicolinate synthase K01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7] D Metbo_1905 Dihydrodipicolinate reductase K00215 dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8] C 00331 Clavulanic acid biosynthesis C 00521 Streptomycin biosynthesis [PATH:mel00521] D Metbo_2461 Phosphoglucosamine mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2] D Metbo_0397 Myo-inositol-1-phosphate synthase K01858 INO1; myo-inositol-1-phosphate synthase [EC:5.5.1.4] D Metbo_2345 Inositol-phosphate phosphatase K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25] D Metbo_0919 glucose-1-phosphate thymidylyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24] D Metbo_2293 Glucosamine-1-phosphate N-acetyltransferase K23144 K23144; UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.7.7.24 2.7.7.83 2.3.1.157 2.3.1.276] D Metbo_2085 dTDP-glucose 4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46] D Metbo_1598 UDP-glucuronate decarboxylase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46] D Metbo_0904 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13] D Metbo_0920 dTDP-4-dehydrorhamnose reductase K00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133] C 00524 Neomycin, kanamycin and gentamicin biosynthesis C 00525 Acarbose and validamycin biosynthesis [PATH:mel00525] D Metbo_0919 glucose-1-phosphate thymidylyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24] D Metbo_2293 Glucosamine-1-phosphate N-acetyltransferase K23144 K23144; UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.7.7.24 2.7.7.83 2.3.1.157 2.3.1.276] D Metbo_2085 dTDP-glucose 4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46] D Metbo_1598 UDP-glucuronate decarboxylase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46] C 00401 Novobiocin biosynthesis [PATH:mel00401] D Metbo_2063 Prephenate dehydrogenase K04517 tyrA2; prephenate dehydrogenase [EC:1.3.1.12] D Metbo_0713 Aspartate transaminase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D Metbo_2295 Histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] C 00404 Staurosporine biosynthesis C 00405 Phenazine biosynthesis D Metbo_2048 anthranilate synthase component I K01657 trpE; anthranilate synthase component I [EC:4.1.3.27] D Metbo_2047 glutamine amidotransferase of anthranilate synthase K01658 trpG; anthranilate synthase component II [EC:4.1.3.27] C 00333 Prodigiosin biosynthesis C 00254 Aflatoxin biosynthesis C 00998 Biosynthesis of various antibiotics C 00999 Biosynthesis of various plant secondary metabolites [PATH:mel00999] D Metbo_0155 S-adenosylmethionine synthase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6] D Metbo_0624 Shikimate dehydrogenase K00014 aroE; shikimate dehydrogenase [EC:1.1.1.25] C 00997 Biosynthesis of various other secondary metabolites B B 09111 Xenobiotics biodegradation and metabolism C 00362 Benzoate degradation [PATH:mel00362] D Metbo_2009 alpha/beta hydrolase fold protein K01055 pcaD; 3-oxoadipate enol-lactonase [EC:3.1.1.24] D Metbo_1026 4-oxalocrotonate tautomerase K01821 praC; 4-oxalocrotonate tautomerase [EC:5.3.2.6] D Metbo_1630 4-oxalocrotonate tautomerase K01821 praC; 4-oxalocrotonate tautomerase [EC:5.3.2.6] D Metbo_1530 4-oxalocrotonate tautomerase K01821 praC; 4-oxalocrotonate tautomerase [EC:5.3.2.6] D Metbo_2126 Carboxymuconolactone decarboxylase K01607 pcaC; 4-carboxymuconolactone decarboxylase [EC:4.1.1.44] D Metbo_1377 Propanoyl-CoA C-acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] C 00627 Aminobenzoate degradation D Metbo_0989 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129] C 00364 Fluorobenzoate degradation C 00625 Chloroalkane and chloroalkene degradation D Metbo_1817 Fe-only nitrogenase, delta subunit K00531 anfG; nitrogenase delta subunit [EC:1.18.6.1] D Metbo_1816 oxidoreductase/nitrogenase component 1 K02591 nifK; nitrogenase molybdenum-iron protein beta chain [EC:1.18.6.1] D Metbo_1181 oxidoreductase/nitrogenase component 1 K02591 nifK; nitrogenase molybdenum-iron protein beta chain [EC:1.18.6.1] D Metbo_2414 Nitrogenase K02591 nifK; nitrogenase molybdenum-iron protein beta chain [EC:1.18.6.1] D Metbo_1819 Nitrogenase iron protein K02588 nifH; nitrogenase iron protein NifH D Metbo_1180 Nitrogenase K02588 nifH; nitrogenase iron protein NifH D Metbo_2415 nitrogenase alpha chain K02586 nifD; nitrogenase molybdenum-iron protein alpha chain [EC:1.18.6.1] D Metbo_1182 oxidoreductase/nitrogenase component 1 K02586 nifD; nitrogenase molybdenum-iron protein alpha chain [EC:1.18.6.1] D Metbo_1818 nitrogenase iron-iron protein, alpha chain K02586 nifD; nitrogenase molybdenum-iron protein alpha chain [EC:1.18.6.1] C 00361 Chlorocyclohexane and chlorobenzene degradation C 00623 Toluene degradation C 00622 Xylene degradation D Metbo_1026 4-oxalocrotonate tautomerase K01821 praC; 4-oxalocrotonate tautomerase [EC:5.3.2.6] D Metbo_1630 4-oxalocrotonate tautomerase K01821 praC; 4-oxalocrotonate tautomerase [EC:5.3.2.6] D Metbo_1530 4-oxalocrotonate tautomerase K01821 praC; 4-oxalocrotonate tautomerase [EC:5.3.2.6] C 00633 Nitrotoluene degradation [PATH:mel00633] D Metbo_0486 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein K00196 cooF; anaerobic carbon-monoxide dehydrogenase iron sulfur subunit D Metbo_0485 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein K00196 cooF; anaerobic carbon-monoxide dehydrogenase iron sulfur subunit D Metbo_0488 Pyruvate synthase K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1] D Metbo_0487 Pyruvate synthase K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1] D Metbo_0490 pyruvate/ketoisovalerate oxidoreductase, gamma subunit K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1] D Metbo_0489 pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1] C 00642 Ethylbenzene degradation C 00643 Styrene degradation C 00791 Atrazine degradation C 00930 Caprolactam degradation C 00363 Bisphenol degradation C 00621 Dioxin degradation D Metbo_1026 4-oxalocrotonate tautomerase K01821 praC; 4-oxalocrotonate tautomerase [EC:5.3.2.6] D Metbo_1630 4-oxalocrotonate tautomerase K01821 praC; 4-oxalocrotonate tautomerase [EC:5.3.2.6] D Metbo_1530 4-oxalocrotonate tautomerase K01821 praC; 4-oxalocrotonate tautomerase [EC:5.3.2.6] C 00626 Naphthalene degradation C 00624 Polycyclic aromatic hydrocarbon degradation C 00365 Furfural degradation C 00984 Steroid degradation C 00980 Metabolism of xenobiotics by cytochrome P450 C 00982 Drug metabolism - cytochrome P450 C 00983 Drug metabolism - other enzymes B B 09112 Not included in regular maps C 09113 Global maps only # A09120 Genetic Information Processing B B 09121 Transcription C 03020 RNA polymerase [PATH:mel03020] D Metbo_2397 DNA-directed RNA polymerase subunit B K03044 rpoB1; DNA-directed RNA polymerase subunit B' [EC:2.7.7.6] D Metbo_2398 RNA polymerase beta subunit K03045 rpoB2; DNA-directed RNA polymerase subunit B" [EC:2.7.7.6] D Metbo_2396 DNA-directed RNA polymerase subunit A' K03041 rpoA1; DNA-directed RNA polymerase subunit A' [EC:2.7.7.6] D Metbo_2395 DNA-directed RNA polymerase subunit A'' K03042 rpoA2; DNA-directed RNA polymerase subunit A" [EC:2.7.7.6] D Metbo_0808 DNA-directed RNA polymerase subunit D K03047 rpoD; DNA-directed RNA polymerase subunit D [EC:2.7.7.6] D Metbo_0200 RNA polymerase dimerization K03056 rpoL; DNA-directed RNA polymerase subunit L [EC:2.7.7.6] D Metbo_0602 DNA-directed RNA polymerase K03049 rpoE1; DNA-directed RNA polymerase subunit E' [EC:2.7.7.6] D Metbo_0193 RNA polymerase Rpb4 K03051 rpoF; DNA-directed RNA polymerase subunit F [EC:2.7.7.6] D Metbo_2399 DNA-directed RNA polymerase subunit H K03053 rpoH; DNA-directed RNA polymerase subunit H [EC:2.7.7.6] D Metbo_0813 DNA-directed RNA polymerase subunit K K03055 rpoK; DNA-directed RNA polymerase subunit K [EC:2.7.7.6] D Metbo_0812 RNA polymerase, N/8 Kd subunit K03058 rpoN; DNA-directed RNA polymerase subunit N [EC:2.7.7.6] D Metbo_2182 RNA polymerase Rbp10 K03059 rpoP; DNA-directed RNA polymerase subunit P [EC:2.7.7.6] C 03022 Basal transcription factors [PATH:mel03022] D Metbo_2336 Transcription initiation factor IIB K03124 TFIIB; transcription initiation factor TFIIB D Metbo_1780 Transcription initiation factor IIB K03124 TFIIB; transcription initiation factor TFIIB D Metbo_2074 TATA-box-binding protein K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein D Metbo_1808 Transcription factor E K03136 TFIIE1; transcription initiation factor TFIIE subunit alpha D Metbo_2239 Transcription factor E K03136 TFIIE1; transcription initiation factor TFIIE subunit alpha C 03040 Spliceosome B B 09122 Translation C 03010 Ribosome [PATH:mel03010] D Metbo_0816 ribosomal protein S2 K02967 RP-S2; small subunit ribosomal protein S2 D Metbo_0780 ribosomal protein S3 K02982 RP-S3; small subunit ribosomal protein S3 D Metbo_0806 ribosomal protein S4 K02986 RP-S4; small subunit ribosomal protein S4 D Metbo_0795 ribosomal protein S5 K02988 RP-S5; small subunit ribosomal protein S5 D Metbo_2391 ribosomal protein S7 K02992 RP-S7; small subunit ribosomal protein S7 D Metbo_0790 ribosomal protein S8 K02994 RP-S8; small subunit ribosomal protein S8 D Metbo_0811 ribosomal protein S9P K02996 RP-S9; small subunit ribosomal protein S9 D Metbo_2388 30S ribosomal protein S10 K02946 RP-S10; small subunit ribosomal protein S10 D Metbo_0807 ribosomal protein S11P K02948 RP-S11; small subunit ribosomal protein S11 D Metbo_2392 ribosomal protein S23 (S12) K02950 RP-S12; small subunit ribosomal protein S12 D Metbo_0805 ribosomal protein S13P K02952 RP-S13; small subunit ribosomal protein S13 D Metbo_0789 ribosomal protein S14 K02954 RP-S14; small subunit ribosomal protein S14 D Metbo_0103 ribosomal protein S15 K02956 RP-S15; small subunit ribosomal protein S15 D Metbo_0784 ribosomal protein S17P K02961 RP-S17; small subunit ribosomal protein S17 D Metbo_0778 ribosomal protein S19 K02965 RP-S19; small subunit ribosomal protein S19 D Metbo_2289 30S ribosomal protein S3Ae K02984 RP-S3Ae; small subunit ribosomal protein S3Ae D Metbo_0787 30S ribosomal protein S4e K02987 RP-S4e; small subunit ribosomal protein S4e D Metbo_0606 30S ribosomal protein S6e K02991 RP-S6e; small subunit ribosomal protein S6e D Metbo_2170 30S ribosomal protein S8e K02995 RP-S8e; small subunit ribosomal protein S8e D Metbo_1908 30S ribosomal protein S17e K02962 RP-S17e; small subunit ribosomal protein S17e D Metbo_0540 Ribosomal protein S19e K02966 RP-S19e; small subunit ribosomal protein S19e D Metbo_0599 30S ribosomal protein S24e K02974 RP-S24e; small subunit ribosomal protein S24e D Metbo_0208 30S ribosomal protein S27e K02978 RP-S27e; small subunit ribosomal protein S27e D Metbo_0598 30S ribosomal protein S27ae K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae D Metbo_1939 hypothetical protein K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae D Metbo_0610 30S ribosomal protein S28e K02979 RP-S28e; small subunit ribosomal protein S28e D Metbo_2251 ribosomal protein L1 K02863 RP-L1; large subunit ribosomal protein L1 D Metbo_0777 Ribosomal protein L2, C-terminal K02886 RP-L2; large subunit ribosomal protein L2 D Metbo_0774 ribosomal protein L3 K02906 RP-L3; large subunit ribosomal protein L3 D Metbo_0788 ribosomal protein L5 K02931 RP-L5; large subunit ribosomal protein L5 D Metbo_0791 ribosomal protein L6P K02933 RP-L6; large subunit ribosomal protein L6 D Metbo_2252 Acidic ribosomal protein P0-like protein K02864 RP-L10; large subunit ribosomal protein L10 D Metbo_2250 Ribosomal protein L11 K02867 RP-L11; large subunit ribosomal protein L11 D Metbo_2253 50S ribosomal protein L12P K02869 RP-L12; large subunit ribosomal protein L12 D Metbo_0810 ribosomal protein L13 K02871 RP-L13; large subunit ribosomal protein L13 D Metbo_0785 50S ribosomal protein L14P K02874 RP-L14; large subunit ribosomal protein L14 D Metbo_0797 50S ribosomal protein L15P K02876 RP-L15; large subunit ribosomal protein L15 D Metbo_0794 ribosomal protein L18P/L5E K02881 RP-L18; large subunit ribosomal protein L18 D Metbo_0779 ribosomal protein L22 K02890 RP-L22; large subunit ribosomal protein L22 D Metbo_0776 ribosomal protein L23 K02892 RP-L23; large subunit ribosomal protein L23 D Metbo_0786 ribosomal protein L24 K02895 RP-L24; large subunit ribosomal protein L24 D Metbo_0781 ribosomal protein L29 K02904 RP-L29; large subunit ribosomal protein L29 D Metbo_0796 ribosomal protein L30P K02907 RP-L30; large subunit ribosomal protein L30 D Metbo_0775 50S ribosomal protein L4P K02930 RP-L4e; large subunit ribosomal protein L4e D Metbo_0611 50S ribosomal protein L7Ae K02936 RP-L7Ae; large subunit ribosomal protein L7Ae D Metbo_0379 50S ribosomal protein L10e K02866 RP-L10e; large subunit ribosomal protein L10e D Metbo_0803 50S ribosomal protein L14e K02875 RP-L14e; large subunit ribosomal protein L14e D Metbo_2192 50S ribosomal protein L15e K02877 RP-L15e; large subunit ribosomal protein L15e D Metbo_0809 50S ribosomal protein L18e K02883 RP-L18e; large subunit ribosomal protein L18e D Metbo_0793 Ribosomal protein L19e K02885 RP-L19e; large subunit ribosomal protein L19e D Metbo_0194 50S ribosomal protein L21e K02889 RP-L21e; large subunit ribosomal protein L21e D Metbo_0609 50S ribosomal protein L24e K02896 RP-L24e; large subunit ribosomal protein L24e D Metbo_2394 50S ribosomal protein L30e K02908 RP-L30e; large subunit ribosomal protein L30e D Metbo_0544 50S ribosomal protein L31e K02910 RP-L31e; large subunit ribosomal protein L31e D Metbo_0792 Ribosomal protein L32e K02912 RP-L32e; large subunit ribosomal protein L32e D Metbo_0801 50S ribosomal protein L34e K02915 RP-L34e; large subunit ribosomal protein L34e D Metbo_2100 50S ribosomal protein L37e K02922 RP-L37e; large subunit ribosomal protein L37e D Metbo_2183 50S ribosomal protein L37Ae K02921 RP-L37Ae; large subunit ribosomal protein L37Ae D Metbo_0543 50S ribosomal protein L39e K02924 RP-L39e; large subunit ribosomal protein L39e D Metbo_2270 50S ribosomal protein L40e K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e D Metbo_0207 Ribosomal protein L44E K02929 RP-L44e; large subunit ribosomal protein L44e D Metbo_0546 50S ribosomal protein LX K02944 RP-LX; large subunit ribosomal protein LX D Metbo_R0019 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D Metbo_R0033 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D Metbo_R0021 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D Metbo_R0031 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D Metbo_R0022 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D Metbo_R0023 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D Metbo_R0030 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA C 00970 Aminoacyl-tRNA biosynthesis [PATH:mel00970] D Metbo_R0020 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D Metbo_R0032 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D Metbo_R0042 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D Metbo_R0006 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D Metbo_R0001 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D Metbo_R0004 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D Metbo_R0005 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D Metbo_R0015 tRNA-Asn K14220 tRNA-Asn; tRNA Asn D Metbo_R0047 tRNA-Asp K14221 tRNA-Asp; tRNA Asp D Metbo_R0009 tRNA-Cys K14222 tRNA-Cys; tRNA Cys D Metbo_R0029 tRNA-Cys K14222 tRNA-Cys; tRNA Cys D Metbo_R0016 tRNA-Gln K14223 tRNA-Gln; tRNA Gln D Metbo_R0026 tRNA-Gln K14223 tRNA-Gln; tRNA Gln D Metbo_R0036 tRNA-Glu K14224 tRNA-Glu; tRNA Glu D Metbo_R0013 tRNA-Glu K14224 tRNA-Glu; tRNA Glu D Metbo_R0044 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D Metbo_R0043 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D Metbo_R0011 tRNA-His K14226 tRNA-His; tRNA His D Metbo_R0040 tRNA-Ile K14227 tRNA-Ile; tRNA Ile D Metbo_R0017 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D Metbo_R0012 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D Metbo_R0035 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D Metbo_R0041 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D Metbo_R0046 tRNA-Lys K14229 tRNA-Lys; tRNA Lys D Metbo_R0034 tRNA-Lys K14229 tRNA-Lys; tRNA Lys D Metbo_R0014 tRNA-Met K14230 tRNA-Met; tRNA Met D Metbo_R0007 tRNA-Met K14230 tRNA-Met; tRNA Met D Metbo_R0051 tRNA-Met K14230 tRNA-Met; tRNA Met D Metbo_R0037 tRNA-Phe K14231 tRNA-Phe; tRNA Phe D Metbo_R0049 tRNA-Pro K14232 tRNA-Pro; tRNA Pro D Metbo_R0045 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D Metbo_R0027 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D Metbo_R0025 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D Metbo_R0039 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D Metbo_R0018 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D Metbo_R0028 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D Metbo_R0050 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D Metbo_R0010 tRNA-Trp K14235 tRNA-Trp; tRNA Trp D Metbo_R0048 tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr D Metbo_R0003 tRNA-Val K14237 tRNA-Val; tRNA Val D Metbo_R0002 tRNA-Val K14237 tRNA-Val; tRNA Val D Metbo_R0038 tRNA-Val K14237 tRNA-Val; tRNA Val D Metbo_0823 glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D Metbo_0049 Glutamyl-tRNA(Gln) amidotransferase subunit A K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7] D Metbo_0314 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7] D Metbo_2448 Glutamyl-tRNA(Gln) amidotransferase subunit D K09482 gatD; glutamyl-tRNA(Gln) amidotransferase subunit D [EC:6.3.5.7] D Metbo_2447 Glutamyl-tRNA(Gln) amidotransferase subunit E K03330 gatE; glutamyl-tRNA(Gln) amidotransferase subunit E [EC:6.3.5.7] D Metbo_2254 alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7] D Metbo_1366 aspartyl-tRNA synthetase K09759 aspC; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23] D Metbo_0661 glycyl-tRNA synthetase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14] D Metbo_0086 threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3] D Metbo_2230 Seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11] D Metbo_0760 pyridoxal phosphate enzyme K01042 selA; L-seryl-tRNA(Ser) seleniumtransferase [EC:2.9.1.1] D Metbo_0044 O-phosphoseryl-tRNA(Cys) synthetase K07587 sepRS; O-phosphoseryl-tRNA synthetase [EC:6.1.1.27] D Metbo_2382 O-phospho-L-seryl-tRNA:Cys-tRNA synthase K06868 sepcysS; Sep-tRNA:Cys-tRNA synthetase [EC:2.5.1.73] D Metbo_1210 cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16] D Metbo_1344 Methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] D Metbo_0943 Valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9] D Metbo_0017 leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D Metbo_0154 Isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5] D Metbo_2526 Lysyl-tRNA synthetase K04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6] D Metbo_0089 Arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D Metbo_1014 Prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15] D Metbo_0622 ATP phosphoribosyltransferase regulatory subunit K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21] D Metbo_1081 Phenylalanyl-tRNA synthetase alpha chain K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20] D Metbo_0950 Phenylalanyl-tRNA synthetase beta chain K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20] D Metbo_0526 Tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D Metbo_0615 tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2] C 03013 Nucleocytoplasmic transport C 03015 mRNA surveillance pathway C 03008 Ribosome biogenesis in eukaryotes B B 09123 Folding, sorting and degradation C 03060 Protein export [PATH:mel03060] D Metbo_0798 preprotein translocase, SecY subunit K03076 secY; preprotein translocase subunit SecY D Metbo_0954 Preprotein translocase, SecD/SecF/SecDF K03072 secD; preprotein translocase subunit SecD D Metbo_0955 Preprotein translocase, SecD/SecF/SecDF K03074 secF; preprotein translocase subunit SecF D Metbo_0196 Signal recognition 54 kDa protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4] D Metbo_R0024 ffs; SRP RNA; RNA component of signal recognition particle K01983 ffs; SRP RNA D Metbo_0548 signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor D Metbo_2248 Preprotein translocase subunit secE K07342 SEC61G; protein transport protein SEC61 subunit gamma and related proteins D Metbo_2119 Signal recognition particle 19 kDa protein K03105 SRP19; signal recognition particle subunit SRP19 D Metbo_0020 arsenite-activated ATPase ArsA K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-] D Metbo_0088 peptidase S26B, signal peptidase K13280 SEC11; signal peptidase I [EC:3.4.21.89] D Metbo_1356 peptidase S26B, signal peptidase K13280 SEC11; signal peptidase I [EC:3.4.21.89] C 04141 Protein processing in endoplasmic reticulum C 04130 SNARE interactions in vesicular transport C 04120 Ubiquitin mediated proteolysis C 04122 Sulfur relay system [PATH:mel04122] D Metbo_1214 Cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D Metbo_1848 Cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D Metbo_1850 SirA-like domain-containing protein K04085 tusA; tRNA 2-thiouridine synthesizing protein A [EC:2.8.1.-] D Metbo_0991 molybdopterin biosynthesis MoaE protein K03635 MOCS2B; molybdopterin synthase catalytic subunit [EC:2.8.1.12] D Metbo_2517 molybdenum cofactor biosynthesis protein A K03639 moaA; GTP 3',8-cyclase [EC:4.1.99.22] D Metbo_1185 MoaD family protein K03636 moaD; sulfur-carrier protein D Metbo_1208 UBA/THIF-type NAD/FAD binding protein K21029 moeB; molybdopterin-synthase adenylyltransferase [EC:2.7.7.80] D Metbo_2483 UBA/THIF-type NAD/FAD binding protein K21029 moeB; molybdopterin-synthase adenylyltransferase [EC:2.7.7.80] D Metbo_1914 molybdenum cofactor biosynthesis protein C K03637 moaC; cyclic pyranopterin monophosphate synthase [EC:4.6.1.17] D Metbo_0680 molybdenum cofactor synthesis domain protein K03638 moaB; molybdopterin adenylyltransferase [EC:2.7.7.75] D Metbo_1266 tRNA sulfurtransferase K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4] D Metbo_1267 hypothetical protein K03154 thiS; sulfur carrier protein D Metbo_0493 thiamineS protein K03154 thiS; sulfur carrier protein C 03050 Proteasome [PATH:mel03050] D Metbo_2222 Proteasome-activating nucleotidase K03420 psmR; proteasome regulatory subunit D Metbo_2188 Proteasome subunit alpha K03432 psmA; proteasome alpha subunit [EC:3.4.25.1] D Metbo_0323 proteasome endopeptidase complex, beta subunit K03433 psmB; proteasome beta subunit [EC:3.4.25.1] C 03018 RNA degradation [PATH:mel03018] D Metbo_0199 RNA-binding domain, S1 K07573 CSL4; exosome complex component CSL4 D Metbo_2184 3' exoribonuclease K12589 RRP42; exosome complex component RRP42 D Metbo_2185 exosome complex exonuclease 1 K11600 RRP41; exosome complex component RRP41 D Metbo_0814 Enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D Metbo_2205 DEAD/DEAH box helicase domain protein K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7] D Metbo_1667 RNA-metabolising metallo-beta-lactamase K12574 rnj; ribonuclease J [EC:3.1.-.-] D Metbo_0821 beta-lactamase domain protein K12574 rnj; ribonuclease J [EC:3.1.-.-] D Metbo_0229 Chaperone protein dnaK K04043 dnaK; molecular chaperone DnaK D Metbo_1585 polyphosphate kinase 1 K00937 ppk1; polyphosphate kinase [EC:2.7.4.1] B B 09124 Replication and repair C 03030 DNA replication [PATH:mel03030] D Metbo_2330 UPF0095 protein K02316 dnaG; DNA primase [EC:2.7.7.101] D Metbo_2431 ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4] D Metbo_0236 DNA polymerase B region K02319 pol; DNA polymerase, archaea type [EC:2.7.7.7] D Metbo_2171 DNA-directed DNA polymerase K02319 pol; DNA polymerase, archaea type [EC:2.7.7.7] D Metbo_1576 DNA polymerase B exonuclease K02319 pol; DNA polymerase, archaea type [EC:2.7.7.7] D Metbo_0115 DNA-directed DNA polymerase K02323 polB; DNA polymerase II small subunit [EC:2.7.7.7] D Metbo_2532 DNA polymerase II large subunit K02322 polC; DNA polymerase II large subunit [EC:2.7.7.7] D Metbo_0529 MCM family protein K10726 mcm; replicative DNA helicase Mcm [EC:5.6.2.3] D Metbo_1347 DNA primase small subunit K02683 priS; DNA primase small subunit [EC:2.7.7.102] D Metbo_1346 DNA primase, large subunit K18882 priL; DNA primase large subunit D Metbo_0167 Replication factor-A domain protein K07466 RFA1; replication factor A1 D Metbo_0205 DNA polymerase sliding clamp K04802 PCNA; proliferating cell nuclear antigen D Metbo_0637 Replication factor C small subunit K04801 rfcS; replication factor C small subunit D Metbo_0636 Replication factor C large subunit K04800 rfcL; replication factor C large subunit D Metbo_2068 Flap structure-specific endonuclease K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-] D Metbo_2463 DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7] C 03410 Base excision repair [PATH:mel03410] D Metbo_0125 DNA-(apurinic or apyrimidinic site) lyase K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18] D Metbo_0940 DNA-(apurinic or apyrimidinic site) lyase K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] D Metbo_0128 3-methyladenine DNA glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21] D Metbo_0205 DNA polymerase sliding clamp K04802 PCNA; proliferating cell nuclear antigen D Metbo_2068 Flap structure-specific endonuclease K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-] D Metbo_2463 DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7] D Metbo_0710 HhH-GPD family protein K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21] D Metbo_0129 DNA-3-methyladenine glycosylase I K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20] D Metbo_2449 exodeoxyribonuclease III Xth K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2] D Metbo_2445 Xylose isomerase domain-containing protein TIM barrel K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2] D Metbo_0104 phosphoesterase RecJ domain protein K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D Metbo_2120 phosphoesterase DHHA1 K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] C 03420 Nucleotide excision repair [PATH:mel03420] D Metbo_1103 UvrABC system protein A K03701 uvrA; excinuclease ABC subunit A D Metbo_1104 UvrABC system protein B K03702 uvrB; excinuclease ABC subunit B D Metbo_1143 UvrABC system protein C K03703 uvrC; excinuclease ABC subunit C D Metbo_1642 UvrD/REP helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] D Metbo_1561 UvrD/REP helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] D Metbo_0167 Replication factor-A domain protein K07466 RFA1; replication factor A1 D Metbo_0205 DNA polymerase sliding clamp K04802 PCNA; proliferating cell nuclear antigen D Metbo_2463 DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7] C 03430 Mismatch repair [PATH:mel03430] D Metbo_0512 DNA mismatch repair protein MutS domain protein K07456 mutS2; DNA mismatch repair protein MutS2 D Metbo_1642 UvrD/REP helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] D Metbo_1561 UvrD/REP helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] D Metbo_0104 phosphoesterase RecJ domain protein K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D Metbo_2120 phosphoesterase DHHA1 K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D Metbo_0694 DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72] D Metbo_0205 DNA polymerase sliding clamp K04802 PCNA; proliferating cell nuclear antigen D Metbo_0167 Replication factor-A domain protein K07466 RFA1; replication factor A1 D Metbo_2463 DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7] C 03440 Homologous recombination [PATH:mel03440] D Metbo_0104 phosphoesterase RecJ domain protein K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D Metbo_2120 phosphoesterase DHHA1 K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D Metbo_1117 putative transcriptional regulator K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4] D Metbo_0167 Replication factor-A domain protein K07466 RFA1; replication factor A1 C 03450 Non-homologous end-joining [PATH:mel03450] D Metbo_2386 Ku domain protein K10979 ku; DNA end-binding protein Ku D Metbo_2068 Flap structure-specific endonuclease K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-] C 03460 Fanconi anemia pathway B B 09126 Chromosome C 03082 ATP-dependent chromatin remodeling C 03083 Polycomb repressive complex B B 09125 Information processing in viruses C 03230 Viral genome structure C 03240 Viral replication C 03250 Viral life cycle - HIV-1 D Metbo_0601 DNA-dependent RNA polymerase, subunit E'' K15171 SUPT4H1; transcription elongation factor SPT4 D Metbo_2249 NusG antitermination factor K15172 SUPT5H; transcription elongation factor SPT5 C 03260 Virion - Human immunodeficiency virus C 03271 Virion - Rotavirus C 03262 Virion - Coronavirus C 03261 Virion - Influenza virus C 03263 Virion - Enterovirus C 03264 Virion - Flavivirus C 03265 Virion - Ebolavirus, Lyssavirus and Morbillivirus C 03266 Virion - Herpesvirus C 03268 Virion - Orthopoxvirus C 03267 Virion - Adenovirus C 03259 Virion - Bacteriophages T4 and T7 C 03258 Virion - Bacteriophage lambda # A09130 Environmental Information Processing B B 09131 Membrane transport C 02010 ABC transporters [PATH:mel02010] D Metbo_2504 extracellular solute-binding protein family 1 K15495 wtpA; molybdate/tungstate transport system substrate-binding protein D Metbo_1093 ABC-type transporter, integral membrane subunit K15496 wtpB; molybdate/tungstate transport system permease protein D Metbo_1092 Polyamine-transporting ATPase K15497 wtpC; molybdate/tungstate transport system ATP-binding protein [EC:7.3.2.5 7.3.2.6] D Metbo_1662 aliphatic sulfonates family ABC transporter, periplasmic ligand-binding protein K15553 ssuA; sulfonate transport system substrate-binding protein D Metbo_1889 ABC-type transporter, periplasmic subunit family 3 K15553 ssuA; sulfonate transport system substrate-binding protein D Metbo_1661 ABC-type transporter, integral membrane subunit K15554 ssuC; sulfonate transport system permease protein D Metbo_1660 Taurine-transporting ATPase K15555 ssuB; sulfonate transport system ATP-binding protein [EC:7.6.2.14] D Metbo_0477 phosphate binding protein K02040 pstS; phosphate transport system substrate-binding protein D Metbo_1594 phosphate binding protein K02040 pstS; phosphate transport system substrate-binding protein D Metbo_0478 phosphate ABC transporter, inner membrane subunit PstC K02037 pstC; phosphate transport system permease protein D Metbo_0479 phosphate ABC transporter, inner membrane subunit PstA K02038 pstA; phosphate transport system permease protein D Metbo_0480 phosphate ABC transporter, ATPase subunit K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1] D Metbo_1702 ABC-type metal ion transporter, periplasmic subunit K09815 znuA; zinc transport system substrate-binding protein D Metbo_1704 ABC-type transporter, integral membrane subunit K09816 znuB; zinc transport system permease protein D Metbo_1703 Phosphonate-transporting ATPase K09817 znuC; zinc transport system ATP-binding protein [EC:7.2.2.20] D Metbo_0753 cobalt transport protein K02009 cbiN; cobalt/nickel transport protein D Metbo_0073 cobalt transport protein CbiN K02009 cbiN; cobalt/nickel transport protein D Metbo_0072 cobalamin (vitamin B12) biosynthesis CbiM protein K02007 cbiM; cobalt/nickel transport system permease protein D Metbo_0752 cobalamin biosynthesis protein CbiM K02007 cbiM; cobalt/nickel transport system permease protein D Metbo_0074 cobalt ABC transporter, inner membrane subunit CbiQ K02008 cbiQ; cobalt/nickel transport system permease protein D Metbo_0754 cobalt ABC transporter, inner membrane subunit CbiQ K02008 cbiQ; cobalt/nickel transport system permease protein D Metbo_1971 cobalt ABC transporter, ATPase subunit K02006 cbiO; cobalt/nickel transport system ATP-binding protein D Metbo_2326 BioY protein K03523 bioY; biotin transport system substrate-specific component D Metbo_0902 ABC-2 type transporter K09690 wzm; homopolymeric O-antigen transport system permease protein D Metbo_0901 Teichoic-acid-transporting ATPase K09691 wzt; homopolymeric O-antigen transport system ATP-binding protein [EC:7.5.2.14] C 02060 Phosphotransferase system (PTS) C 03070 Bacterial secretion system [PATH:mel03070] D Metbo_0954 Preprotein translocase, SecD/SecF/SecDF K03072 secD; preprotein translocase subunit SecD D Metbo_0955 Preprotein translocase, SecD/SecF/SecDF K03074 secF; preprotein translocase subunit SecF D Metbo_0798 preprotein translocase, SecY subunit K03076 secY; preprotein translocase subunit SecY D Metbo_0548 signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor D Metbo_0196 Signal recognition 54 kDa protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4] B B 09132 Signal transduction C 02020 Two-component system [PATH:mel02020] D Metbo_0477 phosphate binding protein K02040 pstS; phosphate transport system substrate-binding protein D Metbo_1594 phosphate binding protein K02040 pstS; phosphate transport system substrate-binding protein D Metbo_1758 Osmosensitive K channel His kinase sensor K07646 kdpD; two-component system, OmpR family, sensor histidine kinase KdpD [EC:2.7.13.3] D Metbo_1761 Potassium-transporting ATPase A chain K01546 kdpA; potassium-transporting ATPase potassium-binding subunit D Metbo_1760 Potassium-transporting ATPase B chain K01547 kdpB; potassium-transporting ATPase ATP-binding subunit [EC:7.2.2.6] D Metbo_1759 Potassium-transporting ATPase C chain K01548 kdpC; potassium-transporting ATPase KdpC subunit D Metbo_1082 triphosphoribosyl-dephospho-CoA protein K05966 citG; triphosphoribosyl-dephospho-CoA synthase [EC:2.4.2.52] D Metbo_0569 nitrogen regulatory protein P-II K04751 glnB; nitrogen regulatory protein P-II 1 D Metbo_0571 nitrogen regulatory protein P-II K04751 glnB; nitrogen regulatory protein P-II 1 D Metbo_2484 glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2] D Metbo_1856 Glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D Metbo_1377 Propanoyl-CoA C-acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Metbo_2283 MCP methyltransferase, CheR-type K00575 cheR; chemotaxis protein methyltransferase CheR [EC:2.1.1.80] D Metbo_1327 MCP methyltransferase/methylesterase, CheR/CheB K13924 cheBR; two-component system, chemotaxis family, CheB/CheR fusion protein [EC:2.1.1.80 3.1.1.61] D Metbo_1666 integral membrane sensor signal transduction histidine kinase K11354 cph1; two-component system, chemotaxis family, sensor kinase Cph1 [EC:2.7.13.3] D Metbo_1775 PAS/PAC sensor signal transduction histidine kinase K11354 cph1; two-component system, chemotaxis family, sensor kinase Cph1 [EC:2.7.13.3] D Metbo_1950 UDP-N-acetylglucosamine 2-epimerase K01791 wecB; UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing) [EC:5.1.3.14] D Metbo_0912 nucleotide sugar dehydrogenase K02472 wecC; UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase [EC:1.1.1.336] C 04010 MAPK signaling pathway C 04013 MAPK signaling pathway - fly C 04016 MAPK signaling pathway - plant C 04011 MAPK signaling pathway - yeast C 04012 ErbB signaling pathway C 04014 Ras signaling pathway C 04015 Rap1 signaling pathway C 04310 Wnt signaling pathway C 04330 Notch signaling pathway C 04340 Hedgehog signaling pathway C 04341 Hedgehog signaling pathway - fly C 04350 TGF-beta signaling pathway C 04390 Hippo signaling pathway C 04391 Hippo signaling pathway - fly C 04392 Hippo signaling pathway - multiple species C 04370 VEGF signaling pathway C 04371 Apelin signaling pathway C 04630 JAK-STAT signaling pathway C 04064 NF-kappa B signaling pathway C 04668 TNF signaling pathway C 04066 HIF-1 signaling pathway C 04068 FoxO signaling pathway C 04020 Calcium signaling pathway C 04070 Phosphatidylinositol signaling system C 04072 Phospholipase D signaling pathway C 04071 Sphingolipid signaling pathway C 04024 cAMP signaling pathway C 04022 cGMP-PKG signaling pathway C 04151 PI3K-Akt signaling pathway C 04152 AMPK signaling pathway C 04150 mTOR signaling pathway C 04075 Plant hormone signal transduction B B 09133 Signaling molecules and interaction C 04080 Neuroactive ligand-receptor interaction C 04060 Cytokine-cytokine receptor interaction C 04061 Viral protein interaction with cytokine and cytokine receptor C 04512 ECM-receptor interaction C 04514 Cell adhesion molecules # A09140 Cellular Processes B B 09141 Transport and catabolism C 04144 Endocytosis C 04145 Phagosome C 04142 Lysosome C 04146 Peroxisome C 04140 Autophagy - animal C 04138 Autophagy - yeast C 04136 Autophagy - other C 04137 Mitophagy - animal C 04139 Mitophagy - yeast C 04148 Efferocytosis B B 09143 Cell growth and death C 04110 Cell cycle C 04111 Cell cycle - yeast C 04112 Cell cycle - Caulobacter C 04113 Meiosis - yeast C 04114 Oocyte meiosis C 04210 Apoptosis C 04214 Apoptosis - fly C 04215 Apoptosis - multiple species C 04216 Ferroptosis C 04217 Necroptosis C 04115 p53 signaling pathway C 04218 Cellular senescence B B 09144 Cellular community - eukaryotes C 04510 Focal adhesion C 04520 Adherens junction C 04530 Tight junction C 04540 Gap junction C 04550 Signaling pathways regulating pluripotency of stem cells B B 09145 Cellular community - prokaryotes C 02024 Quorum sensing [PATH:mel02024] D Metbo_2048 anthranilate synthase component I K01657 trpE; anthranilate synthase component I [EC:4.1.3.27] D Metbo_2047 glutamine amidotransferase of anthranilate synthase K01658 trpG; anthranilate synthase component II [EC:4.1.3.27] D Metbo_1424 glutamate decarboxylase K01580 E4.1.1.15; glutamate decarboxylase [EC:4.1.1.15] D Metbo_1654 glutamate decarboxylase K01580 E4.1.1.15; glutamate decarboxylase [EC:4.1.1.15] D Metbo_0671 beta-lactamase domain protein K13075 ahlD; N-acyl homoserine lactone hydrolase [EC:3.1.1.81] D Metbo_0278 Long-chain-fatty-acid--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Metbo_0798 preprotein translocase, SecY subunit K03076 secY; preprotein translocase subunit SecY D Metbo_0548 signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor D Metbo_0196 Signal recognition 54 kDa protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4] C 05111 Biofilm formation - Vibrio cholerae C 02025 Biofilm formation - Pseudomonas aeruginosa C 02026 Biofilm formation - Escherichia coli B B 09142 Cell motility C 02030 Bacterial chemotaxis [PATH:mel02030] D Metbo_1327 MCP methyltransferase/methylesterase, CheR/CheB K13924 cheBR; two-component system, chemotaxis family, CheB/CheR fusion protein [EC:2.1.1.80 3.1.1.61] D Metbo_2283 MCP methyltransferase, CheR-type K00575 cheR; chemotaxis protein methyltransferase CheR [EC:2.1.1.80] C 02040 Flagellar assembly C 04814 Motor proteins C 04820 Cytoskeleton in muscle cells D Metbo_0814 Enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] C 04810 Regulation of actin cytoskeleton # A09150 Organismal Systems B B 09151 Immune system C 04640 Hematopoietic cell lineage C 04610 Complement and coagulation cascades C 04611 Platelet activation C 04613 Neutrophil extracellular trap formation C 04620 Toll-like receptor signaling pathway C 04624 Toll and Imd signaling pathway C 04621 NOD-like receptor signaling pathway C 04622 RIG-I-like receptor signaling pathway C 04623 Cytosolic DNA-sensing pathway C 04625 C-type lectin receptor signaling pathway C 04650 Natural killer cell mediated cytotoxicity C 04612 Antigen processing and presentation C 04660 T cell receptor signaling pathway C 04658 Th1 and Th2 cell differentiation C 04659 Th17 cell differentiation C 04657 IL-17 signaling pathway C 04662 B cell receptor signaling pathway C 04664 Fc epsilon RI signaling pathway C 04666 Fc gamma R-mediated phagocytosis C 04670 Leukocyte transendothelial migration C 04672 Intestinal immune network for IgA production C 04062 Chemokine signaling pathway B B 09152 Endocrine system C 04911 Insulin secretion C 04910 Insulin signaling pathway C 04922 Glucagon signaling pathway C 04923 Regulation of lipolysis in adipocytes C 04920 Adipocytokine signaling pathway C 03320 PPAR signaling pathway C 04929 GnRH secretion C 04912 GnRH signaling pathway C 04913 Ovarian steroidogenesis C 04915 Estrogen signaling pathway C 04914 Progesterone-mediated oocyte maturation C 04917 Prolactin signaling pathway C 04921 Oxytocin signaling pathway C 04926 Relaxin signaling pathway C 04935 Growth hormone synthesis, secretion and action C 04918 Thyroid hormone synthesis C 04919 Thyroid hormone signaling pathway C 04928 Parathyroid hormone synthesis, secretion and action C 04916 Melanogenesis C 04924 Renin secretion C 04614 Renin-angiotensin system C 04925 Aldosterone synthesis and secretion C 04927 Cortisol synthesis and secretion B B 09153 Circulatory system C 04260 Cardiac muscle contraction C 04261 Adrenergic signaling in cardiomyocytes C 04270 Vascular smooth muscle contraction B B 09154 Digestive system C 04970 Salivary secretion C 04971 Gastric acid secretion C 04972 Pancreatic secretion C 04976 Bile secretion C 04973 Carbohydrate digestion and absorption C 04974 Protein digestion and absorption C 04975 Fat digestion and absorption C 04979 Cholesterol metabolism C 04977 Vitamin digestion and absorption C 04980 Cobalamin transport and metabolism C 04978 Mineral absorption B B 09155 Excretory system C 04962 Vasopressin-regulated water reabsorption C 04960 Aldosterone-regulated sodium reabsorption C 04961 Endocrine and other factor-regulated calcium reabsorption C 04964 Proximal tubule bicarbonate reclamation C 04966 Collecting duct acid secretion B B 09156 Nervous system C 04724 Glutamatergic synapse C 04727 GABAergic synapse C 04725 Cholinergic synapse C 04728 Dopaminergic synapse C 04726 Serotonergic synapse C 04720 Long-term potentiation C 04730 Long-term depression C 04723 Retrograde endocannabinoid signaling C 04721 Synaptic vesicle cycle C 04722 Neurotrophin signaling pathway B B 09157 Sensory system C 04744 Phototransduction C 04745 Phototransduction - fly C 04740 Olfactory transduction C 04742 Taste transduction C 04750 Inflammatory mediator regulation of TRP channels B B 09158 Development and regeneration C 04320 Dorso-ventral axis formation C 04360 Axon guidance C 04361 Axon regeneration C 04380 Osteoclast differentiation B B 09149 Aging C 04211 Longevity regulating pathway C 04212 Longevity regulating pathway - worm C 04213 Longevity regulating pathway - multiple species B B 09159 Environmental adaptation C 04710 Circadian rhythm C 04713 Circadian entrainment C 04711 Circadian rhythm - fly C 04712 Circadian rhythm - plant C 04714 Thermogenesis C 04626 Plant-pathogen interaction # A09160 Human Diseases B B 09161 Cancer: overview C 05200 Pathways in cancer C 05202 Transcriptional misregulation in cancer C 05206 MicroRNAs in cancer C 05205 Proteoglycans in cancer C 05204 Chemical carcinogenesis - DNA adducts C 05207 Chemical carcinogenesis - receptor activation C 05208 Chemical carcinogenesis - reactive oxygen species C 05203 Viral carcinogenesis C 05230 Central carbon metabolism in cancer C 05231 Choline metabolism in cancer C 05235 PD-L1 expression and PD-1 checkpoint pathway in cancer B B 09162 Cancer: specific types C 05210 Colorectal cancer C 05212 Pancreatic cancer C 05225 Hepatocellular carcinoma C 05226 Gastric cancer C 05214 Glioma C 05216 Thyroid cancer C 05221 Acute myeloid leukemia C 05220 Chronic myeloid leukemia C 05217 Basal cell carcinoma C 05218 Melanoma C 05211 Renal cell carcinoma C 05219 Bladder cancer C 05215 Prostate cancer C 05213 Endometrial cancer C 05224 Breast cancer C 05222 Small cell lung cancer C 05223 Non-small cell lung cancer B B 09172 Infectious disease: viral C 05166 Human T-cell leukemia virus 1 infection C 05170 Human immunodeficiency virus 1 infection C 05161 Hepatitis B C 05160 Hepatitis C C 05171 Coronavirus disease - COVID-19 C 05164 Influenza A C 05162 Measles C 05168 Herpes simplex virus 1 infection C 05163 Human cytomegalovirus infection C 05167 Kaposi sarcoma-associated herpesvirus infection C 05169 Epstein-Barr virus infection C 05165 Human papillomavirus infection B B 09171 Infectious disease: bacterial C 05110 Vibrio cholerae infection C 05120 Epithelial cell signaling in Helicobacter pylori infection C 05130 Pathogenic Escherichia coli infection C 05132 Salmonella infection C 05131 Shigellosis C 05135 Yersinia infection C 05133 Pertussis C 05134 Legionellosis C 05150 Staphylococcus aureus infection C 05152 Tuberculosis C 05100 Bacterial invasion of epithelial cells B B 09174 Infectious disease: parasitic C 05146 Amoebiasis C 05144 Malaria C 05145 Toxoplasmosis C 05140 Leishmaniasis C 05142 Chagas disease C 05143 African trypanosomiasis B B 09163 Immune disease C 05310 Asthma C 05322 Systemic lupus erythematosus C 05323 Rheumatoid arthritis C 05320 Autoimmune thyroid disease C 05321 Inflammatory bowel disease C 05330 Allograft rejection C 05332 Graft-versus-host disease C 05340 Primary immunodeficiency B B 09164 Neurodegenerative disease C 05010 Alzheimer disease C 05012 Parkinson disease C 05014 Amyotrophic lateral sclerosis C 05016 Huntington disease C 05017 Spinocerebellar ataxia C 05020 Prion disease C 05022 Pathways of neurodegeneration - multiple diseases B B 09165 Substance dependence C 05030 Cocaine addiction C 05031 Amphetamine addiction C 05032 Morphine addiction C 05033 Nicotine addiction C 05034 Alcoholism B B 09166 Cardiovascular disease C 05417 Lipid and atherosclerosis C 05418 Fluid shear stress and atherosclerosis C 05410 Hypertrophic cardiomyopathy C 05412 Arrhythmogenic right ventricular cardiomyopathy C 05414 Dilated cardiomyopathy C 05415 Diabetic cardiomyopathy C 05416 Viral myocarditis B B 09167 Endocrine and metabolic disease C 04930 Type II diabetes mellitus C 04940 Type I diabetes mellitus C 04950 Maturity onset diabetes of the young C 04936 Alcoholic liver disease C 04932 Non-alcoholic fatty liver disease C 04931 Insulin resistance C 04933 AGE-RAGE signaling pathway in diabetic complications C 04934 Cushing syndrome B B 09175 Drug resistance: antimicrobial C 01501 beta-Lactam resistance C 01502 Vancomycin resistance [PATH:mel01502] D Metbo_2214 Phospho-N-acetylmuramoyl-pentapeptide-transferase K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13] D Metbo_2055 MurG-related protein K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227] D Metbo_0734 Glycosyltransferase 28 domain protein K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227] C 01503 Cationic antimicrobial peptide (CAMP) resistance B B 09176 Drug resistance: antineoplastic C 01521 EGFR tyrosine kinase inhibitor resistance C 01524 Platinum drug resistance C 01523 Antifolate resistance C 01522 Endocrine resistance # A09180 Brite Hierarchies B B 09181 Protein families: metabolism C 01000 Enzymes [BR:mel01000] C 01001 Protein kinases [BR:mel01001] D Metbo_0101 O-sialoglycoprotein endopeptidase K15904 kae1-bud32; bifunctional N6-L-threonylcarbamoyladenine synthase / protein kinase Bud32 [EC:2.3.1.234 2.7.11.1] D Metbo_2372 Non-specific serine/threonine protein kinase K07178 RIOK1; RIO kinase 1 [EC:2.7.11.1] D Metbo_1758 Osmosensitive K channel His kinase sensor K07646 kdpD; two-component system, OmpR family, sensor histidine kinase KdpD [EC:2.7.13.3] D Metbo_1666 integral membrane sensor signal transduction histidine kinase K11354 cph1; two-component system, chemotaxis family, sensor kinase Cph1 [EC:2.7.13.3] D Metbo_1775 PAS/PAC sensor signal transduction histidine kinase K11354 cph1; two-component system, chemotaxis family, sensor kinase Cph1 [EC:2.7.13.3] D Metbo_1329 signal transduction histidine kinase K00936 pdtaS; two-component system, sensor histidine kinase PdtaS [EC:2.7.13.3] D Metbo_1823 signal transduction histidine kinase K00936 pdtaS; two-component system, sensor histidine kinase PdtaS [EC:2.7.13.3] C 01009 Protein phosphatases and associated proteins [BR:mel01009] D Metbo_0528 Translation initiation factor 2 subunit beta K03238 EIF2S2; translation initiation factor 2 subunit 2 D Metbo_2075 phosphoserine phosphatase SerB K01079 serB; phosphoserine phosphatase [EC:3.1.3.3] C 01002 Peptidases and inhibitors [BR:mel01002] D Metbo_1168 Peptidase A24A domain protein K07991 flaK; archaeal preflagellin peptidase FlaK [EC:3.4.23.52] D Metbo_2212 hydrogenase maturation protease HycI K08315 hycI; hydrogenase 3 maturation protease [EC:3.4.23.51] D Metbo_2355 GMP synthase (glutamine-hydrolyzing) subunit A K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] D Metbo_2358 GMP synthase, large subunit K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] D Metbo_2098 amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14] D Metbo_2109 Glucosamine--fructose-6-phosphate aminotransferase (isomerizing) K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] D Metbo_1749 Glutamine--fructose-6-phosphate transaminase (isomerizing) K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] D Metbo_1176 asparagine synthase (glutamine-hydrolyzing) K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4] D Metbo_0846 asparagine synthase K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4] D Metbo_1234 intracellular protease, PfpI family K05520 yhbO; deglycase [EC:3.5.1.124] D Metbo_0643 peptidase C60 sortase A and B K07284 srtA; sortase A [EC:3.4.22.70] D Metbo_2424 sortase family protein K07284 srtA; sortase A [EC:3.4.22.70] D Metbo_1826 peptidase C60 sortase A and B K07284 srtA; sortase A [EC:3.4.22.70] D Metbo_1074 Abortive infection protein K07052 K07052; CAAX protease family protein D Metbo_0335 Abortive infection protein K07052 K07052; CAAX protease family protein D Metbo_1260 Abortive infection protein K07052 K07052; CAAX protease family protein D Metbo_0840 Abortive infection protein K07052 K07052; CAAX protease family protein D Metbo_1299 peptidase T-like protein K01258 pepT; tripeptide aminopeptidase [EC:3.4.11.4] D Metbo_0223 methionine aminopeptidase, type II K01265 map; methionyl aminopeptidase [EC:3.4.11.18] D Metbo_0222 methionine aminopeptidase, type II K01265 map; methionyl aminopeptidase [EC:3.4.11.18] D Metbo_0981 peptidase M48 Ste24p K03799 htpX; heat shock protein HtpX [EC:3.4.24.-] D Metbo_0632 protease htpX K03799 htpX; heat shock protein HtpX [EC:3.4.24.-] D Metbo_1472 protease htpX K03799 htpX; heat shock protein HtpX [EC:3.4.24.-] D Metbo_2301 anti-sigma H sporulation factor, LonB K01338 lon; ATP-dependent Lon protease [EC:3.4.21.53] D Metbo_2329 ATPase associated with various cellular activities AAA_5 K01338 lon; ATP-dependent Lon protease [EC:3.4.21.53] D Metbo_1509 peptidase S16, Lon-like protease K04076 lonB; ATP-dependent Lon protease [EC:3.4.21.53] D Metbo_2206 peptidase S16, Lon-like protease K04076 lonB; ATP-dependent Lon protease [EC:3.4.21.53] D Metbo_0088 peptidase S26B, signal peptidase K13280 SEC11; signal peptidase I [EC:3.4.21.89] D Metbo_1356 peptidase S26B, signal peptidase K13280 SEC11; signal peptidase I [EC:3.4.21.89] D Metbo_1911 signal peptide peptidase SppA, 36K type K04773 sppA; protease IV [EC:3.4.21.-] D Metbo_2188 Proteasome subunit alpha K03432 psmA; proteasome alpha subunit [EC:3.4.25.1] D Metbo_0323 proteasome endopeptidase complex, beta subunit K03433 psmB; proteasome beta subunit [EC:3.4.25.1] D Metbo_2097 peptidase U32 K08303 prtC; U32 family peptidase [EC:3.4.-.-] D Metbo_0515 peptidase U32 K08303 prtC; U32 family peptidase [EC:3.4.-.-] D Metbo_2261 peptidase U62 modulator of DNA gyrase K03592 pmbA; PmbA protein D Metbo_1964 peptidase U62 modulator of DNA gyrase K03568 tldD; TldD protein C 01003 Glycosyltransferases [BR:mel01003] D Metbo_0719 Oligosaccharyl transferase STT3 subunit K21306 aglB; dolichyl-phosphooligosaccharide-protein glycotransferase [EC:2.4.99.21] D Metbo_0534 Oligosaccharyl transferase STT3 subunit K21306 aglB; dolichyl-phosphooligosaccharide-protein glycotransferase [EC:2.4.99.21] D Metbo_0771 hypothetical protein K20151 fucT; alpha(1,3/1,4) fucosyltransferase [EC:2.4.1.65 2.4.1.152] D Metbo_0176 glycosyl transferase family 2 K13693 gpgS; glucosyl-3-phosphoglycerate synthase [EC:2.4.1.266] C 01005 Lipopolysaccharide biosynthesis proteins [BR:mel01005] C 01011 Peptidoglycan biosynthesis and degradation proteins [BR:mel01011] D Metbo_2217 Mur ligase middle domain protein K01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8] D Metbo_2264 UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9] D Metbo_2215 Mur ligase middle domain protein K01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13] D Metbo_2214 Phospho-N-acetylmuramoyl-pentapeptide-transferase K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13] D Metbo_2055 MurG-related protein K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227] D Metbo_0734 Glycosyltransferase 28 domain protein K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227] D Metbo_0099 Undecaprenyl-diphosphatase K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27] D Metbo_0878 Undecaprenyl-diphosphatase K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27] D Metbo_0643 peptidase C60 sortase A and B K07284 srtA; sortase A [EC:3.4.22.70] D Metbo_2424 sortase family protein K07284 srtA; sortase A [EC:3.4.22.70] D Metbo_1826 peptidase C60 sortase A and B K07284 srtA; sortase A [EC:3.4.22.70] C 01004 Lipid biosynthesis proteins [BR:mel01004] D Metbo_1898 acetate/CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D Metbo_1715 acetate/CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D Metbo_2455 Butyrate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D Metbo_0567 acetate/CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D Metbo_1651 CoA-binding domain protein K24012 acdAB; acetate---CoA ligase (ADP-forming) [EC:6.2.1.13] D Metbo_0278 Long-chain-fatty-acid--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] C 01008 Polyketide biosynthesis proteins C 01006 Prenyltransferases [BR:mel01006] D Metbo_0822 Dimethylallyltranstransferase K13787 idsA; geranylgeranyl diphosphate synthase, type I [EC:2.5.1.1 2.5.1.10 2.5.1.29] D Metbo_2001 UbiA prenyltransferase K02548 menA; 1,4-dihydroxy-2-naphthoate polyprenyltransferase [EC:2.5.1.74] D Metbo_2002 UbiA prenyltransferase K02548 menA; 1,4-dihydroxy-2-naphthoate polyprenyltransferase [EC:2.5.1.74] C 01007 Amino acid related enzymes [BR:mel01007] D Metbo_2526 Lysyl-tRNA synthetase K04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6] D Metbo_0823 glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D Metbo_0526 Tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D Metbo_0615 tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2] D Metbo_1210 cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16] D Metbo_0089 Arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D Metbo_1344 Methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] D Metbo_0154 Isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5] D Metbo_0943 Valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9] D Metbo_0017 leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D Metbo_1366 aspartyl-tRNA synthetase K09759 aspC; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23] D Metbo_0622 ATP phosphoribosyltransferase regulatory subunit K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21] D Metbo_0661 glycyl-tRNA synthetase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14] D Metbo_2230 Seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11] D Metbo_1014 Prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15] D Metbo_0086 threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3] D Metbo_2254 alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7] D Metbo_0044 O-phosphoseryl-tRNA(Cys) synthetase K07587 sepRS; O-phosphoseryl-tRNA synthetase [EC:6.1.1.27] D Metbo_1081 Phenylalanyl-tRNA synthetase alpha chain K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20] D Metbo_0950 Phenylalanyl-tRNA synthetase beta chain K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20] D Metbo_0713 Aspartate transaminase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1] D Metbo_0824 LL-diaminopimelate aminotransferase K10206 E2.6.1.83; LL-diaminopimelate aminotransferase [EC:2.6.1.83] D Metbo_2295 Histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] D Metbo_1184 Cystathionine beta-lyase K14155 patB; cysteine-S-conjugate beta-lyase [EC:4.4.1.13] D Metbo_0120 Acetylornithine/succinyldiaminopimelate aminotransferase K00821 argD; acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17] D Metbo_2131 Glutamate-1-semialdehyde 2,1-aminomutase K01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8] D Metbo_0098 branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] C 00199 Cytochrome P450 C 00194 Photosynthesis proteins [BR:mel00194] B B 09182 Protein families: genetic information processing C 03000 Transcription factors [BR:mel03000] D Metbo_0167 Replication factor-A domain protein K07466 RFA1; replication factor A1 D Metbo_2074 TATA-box-binding protein K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein D Metbo_2383 transcriptional activator ligand binding domain protein K13652 K13652; AraC family transcriptional regulator D Metbo_1161 transcriptional regulator, TetR family K09017 rutR; TetR/AcrR family transcriptional regulator D Metbo_0185 transcriptional regulator, AsnC family K03718 asnC; Lrp/AsnC family transcriptional regulator, regulator for asnA, asnC and gidA D Metbo_1937 regulatory protein MarR K06075 slyA; MarR family transcriptional regulator, transcriptional regulator for hemolysin D Metbo_0880 transcriptional regulator, MarR family K15973 mhqR; MarR family transcriptional regulator, 2-MHQ and catechol-resistance regulon repressor D Metbo_1891 cobalamin B12-binding domain protein K22491 litR; MerR family transcriptional regulator, light-induced transcriptional regulator D Metbo_2300 regulatory protein ArsR K03892 arsR; ArsR family transcriptional regulator, arsenate/arsenite/antimonite-responsive transcriptional repressor D Metbo_1238 transcriptional regulator, ArsR family K21903 cadC; ArsR family transcriptional regulator, lead/cadmium/zinc/bismuth-responsive transcriptional repressor D Metbo_0231 transcriptional regulator, ArsR family K07721 K07721; ArsR family transcriptional regulator D Metbo_1257 transcriptional regulator, PadR-like family K10947 K10947; PadR family transcriptional regulator D Metbo_1610 transcriptional regulator PadR family protein K10947 K10947; PadR family transcriptional regulator D Metbo_0059 transcriptional regulator, PadR-like family K10947 K10947; PadR family transcriptional regulator D Metbo_1310 transcriptional regulator, PadR-like family K10947 K10947; PadR family transcriptional regulator D Metbo_1030 iron (metal) dependent repressor, DtxR family K03709 troR; DtxR family transcriptional regulator, Mn-dependent transcriptional regulator D Metbo_0763 biotin/acetyl-CoA-carboxylase ligase K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15] D Metbo_2485 protein of unknown function DUF128 K09720 nrpRI; HTH-type transcriptional regulator, global nitrogen regulator NrpRI D Metbo_2143 transcriptional regulator, TrmB K23356 trmB; HTH-type transcriptional regulator, sugar sensing transcriptional regulator D Metbo_1461 transcriptional regulator, TrmB K23356 trmB; HTH-type transcriptional regulator, sugar sensing transcriptional regulator D Metbo_2340 PyrE-like protein K26599 gfcR; HTH-type transcriptional regulator, activator of D-glucose/D-fructose catabolism D Metbo_2503 putative transcriptional regulator, ModE family K02019 modE; molybdate transport system regulatory protein D Metbo_0746 CRISPR locus-related DNA-binding protein K07725 csa3; CRISPR-associated protein Csa3 D Metbo_0425 transcriptional regulator, XRE family K07728 K07728; putative transcriptional regulator D Metbo_1196 transcriptional regulator, XRE family K07729 K07729; putative transcriptional regulator D Metbo_2121 regulatory protein Crp K07730 K07730; putative transcriptional regulator D Metbo_1701 transcriptional regulator NikR, CopG family K07722 nikR; CopG family transcriptional regulator, nickel-responsive regulator D Metbo_2210 transcriptional regulator NikR, CopG family K07722 nikR; CopG family transcriptional regulator, nickel-responsive regulator C 03021 Transcription machinery [BR:mel03021] D Metbo_2336 Transcription initiation factor IIB K03124 TFIIB; transcription initiation factor TFIIB D Metbo_1780 Transcription initiation factor IIB K03124 TFIIB; transcription initiation factor TFIIB D Metbo_2074 TATA-box-binding protein K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein D Metbo_1808 Transcription factor E K03136 TFIIE1; transcription initiation factor TFIIE subunit alpha D Metbo_2239 Transcription factor E K03136 TFIIE1; transcription initiation factor TFIIE subunit alpha D Metbo_0601 DNA-dependent RNA polymerase, subunit E'' K15171 SUPT4H1; transcription elongation factor SPT4 D Metbo_2249 NusG antitermination factor K15172 SUPT5H; transcription elongation factor SPT5 D Metbo_2393 NusA family KH domain protein K02600 nusA; transcription termination/antitermination protein NusA D Metbo_2396 DNA-directed RNA polymerase subunit A' K03041 rpoA1; DNA-directed RNA polymerase subunit A' [EC:2.7.7.6] D Metbo_2395 DNA-directed RNA polymerase subunit A'' K03042 rpoA2; DNA-directed RNA polymerase subunit A" [EC:2.7.7.6] D Metbo_2397 DNA-directed RNA polymerase subunit B K03044 rpoB1; DNA-directed RNA polymerase subunit B' [EC:2.7.7.6] D Metbo_2398 RNA polymerase beta subunit K03045 rpoB2; DNA-directed RNA polymerase subunit B" [EC:2.7.7.6] D Metbo_0808 DNA-directed RNA polymerase subunit D K03047 rpoD; DNA-directed RNA polymerase subunit D [EC:2.7.7.6] D Metbo_0602 DNA-directed RNA polymerase K03049 rpoE1; DNA-directed RNA polymerase subunit E' [EC:2.7.7.6] D Metbo_0193 RNA polymerase Rpb4 K03051 rpoF; DNA-directed RNA polymerase subunit F [EC:2.7.7.6] D Metbo_2399 DNA-directed RNA polymerase subunit H K03053 rpoH; DNA-directed RNA polymerase subunit H [EC:2.7.7.6] D Metbo_0813 DNA-directed RNA polymerase subunit K K03055 rpoK; DNA-directed RNA polymerase subunit K [EC:2.7.7.6] D Metbo_0200 RNA polymerase dimerization K03056 rpoL; DNA-directed RNA polymerase subunit L [EC:2.7.7.6] D Metbo_0812 RNA polymerase, N/8 Kd subunit K03058 rpoN; DNA-directed RNA polymerase subunit N [EC:2.7.7.6] D Metbo_2182 RNA polymerase Rbp10 K03059 rpoP; DNA-directed RNA polymerase subunit P [EC:2.7.7.6] D Metbo_0203 transcription termination factor Tfs K03057 tfs; transcription factor S C 03019 Messenger RNA biogenesis [BR:mel03019] D Metbo_0601 DNA-dependent RNA polymerase, subunit E'' K15171 SUPT4H1; transcription elongation factor SPT4 D Metbo_2249 NusG antitermination factor K15172 SUPT5H; transcription elongation factor SPT5 D Metbo_2064 AAA family ATPase, CDC48 subfamily K13525 VCP; transitional endoplasmic reticulum ATPase D Metbo_2060 Pelota-like protein K06965 PELO; protein pelota D Metbo_2339 Peptide chain release factor subunit 1 K03265 ETF1; peptide chain release factor subunit 1 D Metbo_0339 protein synthesis factor GTP-binding protein K03231 EEF1A; elongation factor 1-alpha D Metbo_2389 translation elongation factor EF-1, subunit alpha K03231 EEF1A; elongation factor 1-alpha D Metbo_0199 RNA-binding domain, S1 K07573 CSL4; exosome complex component CSL4 D Metbo_2185 exosome complex exonuclease 1 K11600 RRP41; exosome complex component RRP41 D Metbo_2184 3' exoribonuclease K12589 RRP42; exosome complex component RRP42 D Metbo_1667 RNA-metabolising metallo-beta-lactamase K12574 rnj; ribonuclease J [EC:3.1.-.-] D Metbo_0821 beta-lactamase domain protein K12574 rnj; ribonuclease J [EC:3.1.-.-] D Metbo_0519 metal dependent phosphohydrolase K03698 cbf; 3'-5' exoribonuclease [EC:3.1.-.-] D Metbo_2205 DEAD/DEAH box helicase domain protein K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7] D Metbo_0814 Enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D Metbo_0229 Chaperone protein dnaK K04043 dnaK; molecular chaperone DnaK D Metbo_1585 polyphosphate kinase 1 K00937 ppk1; polyphosphate kinase [EC:2.7.4.1] D Metbo_2104 DEAD/DEAH box helicase domain protein K03725 K03725; putative ATP-dependent RNA helicase [EC:5.6.2.-] C 03041 Spliceosome [BR:mel03041] D Metbo_0650 ZPR1-related zinc finger protein K06874 ZPR1; zinc finger protein ZPR1 C 03011 Ribosome [BR:mel03011] D Metbo_2289 30S ribosomal protein S3Ae K02984 RP-S3Ae; small subunit ribosomal protein S3Ae D Metbo_0787 30S ribosomal protein S4e K02987 RP-S4e; small subunit ribosomal protein S4e D Metbo_0606 30S ribosomal protein S6e K02991 RP-S6e; small subunit ribosomal protein S6e D Metbo_2170 30S ribosomal protein S8e K02995 RP-S8e; small subunit ribosomal protein S8e D Metbo_1908 30S ribosomal protein S17e K02962 RP-S17e; small subunit ribosomal protein S17e D Metbo_0540 Ribosomal protein S19e K02966 RP-S19e; small subunit ribosomal protein S19e D Metbo_0599 30S ribosomal protein S24e K02974 RP-S24e; small subunit ribosomal protein S24e D Metbo_0208 30S ribosomal protein S27e K02978 RP-S27e; small subunit ribosomal protein S27e D Metbo_0598 30S ribosomal protein S27ae K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae D Metbo_1939 hypothetical protein K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae D Metbo_0610 30S ribosomal protein S28e K02979 RP-S28e; small subunit ribosomal protein S28e D Metbo_0775 50S ribosomal protein L4P K02930 RP-L4e; large subunit ribosomal protein L4e D Metbo_0611 50S ribosomal protein L7Ae K02936 RP-L7Ae; large subunit ribosomal protein L7Ae D Metbo_0379 50S ribosomal protein L10e K02866 RP-L10e; large subunit ribosomal protein L10e D Metbo_0803 50S ribosomal protein L14e K02875 RP-L14e; large subunit ribosomal protein L14e D Metbo_2192 50S ribosomal protein L15e K02877 RP-L15e; large subunit ribosomal protein L15e D Metbo_0809 50S ribosomal protein L18e K02883 RP-L18e; large subunit ribosomal protein L18e D Metbo_0793 Ribosomal protein L19e K02885 RP-L19e; large subunit ribosomal protein L19e D Metbo_0194 50S ribosomal protein L21e K02889 RP-L21e; large subunit ribosomal protein L21e D Metbo_0609 50S ribosomal protein L24e K02896 RP-L24e; large subunit ribosomal protein L24e D Metbo_2394 50S ribosomal protein L30e K02908 RP-L30e; large subunit ribosomal protein L30e D Metbo_0544 50S ribosomal protein L31e K02910 RP-L31e; large subunit ribosomal protein L31e D Metbo_0792 Ribosomal protein L32e K02912 RP-L32e; large subunit ribosomal protein L32e D Metbo_0801 50S ribosomal protein L34e K02915 RP-L34e; large subunit ribosomal protein L34e D Metbo_2100 50S ribosomal protein L37e K02922 RP-L37e; large subunit ribosomal protein L37e D Metbo_2183 50S ribosomal protein L37Ae K02921 RP-L37Ae; large subunit ribosomal protein L37Ae D Metbo_0543 50S ribosomal protein L39e K02924 RP-L39e; large subunit ribosomal protein L39e D Metbo_2270 50S ribosomal protein L40e K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e D Metbo_0207 Ribosomal protein L44E K02929 RP-L44e; large subunit ribosomal protein L44e D Metbo_0816 ribosomal protein S2 K02967 RP-S2; small subunit ribosomal protein S2 D Metbo_0780 ribosomal protein S3 K02982 RP-S3; small subunit ribosomal protein S3 D Metbo_0806 ribosomal protein S4 K02986 RP-S4; small subunit ribosomal protein S4 D Metbo_0795 ribosomal protein S5 K02988 RP-S5; small subunit ribosomal protein S5 D Metbo_2391 ribosomal protein S7 K02992 RP-S7; small subunit ribosomal protein S7 D Metbo_0790 ribosomal protein S8 K02994 RP-S8; small subunit ribosomal protein S8 D Metbo_0811 ribosomal protein S9P K02996 RP-S9; small subunit ribosomal protein S9 D Metbo_2388 30S ribosomal protein S10 K02946 RP-S10; small subunit ribosomal protein S10 D Metbo_0807 ribosomal protein S11P K02948 RP-S11; small subunit ribosomal protein S11 D Metbo_2392 ribosomal protein S23 (S12) K02950 RP-S12; small subunit ribosomal protein S12 D Metbo_0805 ribosomal protein S13P K02952 RP-S13; small subunit ribosomal protein S13 D Metbo_0789 ribosomal protein S14 K02954 RP-S14; small subunit ribosomal protein S14 D Metbo_0103 ribosomal protein S15 K02956 RP-S15; small subunit ribosomal protein S15 D Metbo_0784 ribosomal protein S17P K02961 RP-S17; small subunit ribosomal protein S17 D Metbo_0778 ribosomal protein S19 K02965 RP-S19; small subunit ribosomal protein S19 D Metbo_2251 ribosomal protein L1 K02863 RP-L1; large subunit ribosomal protein L1 D Metbo_0777 Ribosomal protein L2, C-terminal K02886 RP-L2; large subunit ribosomal protein L2 D Metbo_0774 ribosomal protein L3 K02906 RP-L3; large subunit ribosomal protein L3 D Metbo_0788 ribosomal protein L5 K02931 RP-L5; large subunit ribosomal protein L5 D Metbo_0791 ribosomal protein L6P K02933 RP-L6; large subunit ribosomal protein L6 D Metbo_2252 Acidic ribosomal protein P0-like protein K02864 RP-L10; large subunit ribosomal protein L10 D Metbo_2250 Ribosomal protein L11 K02867 RP-L11; large subunit ribosomal protein L11 D Metbo_0810 ribosomal protein L13 K02871 RP-L13; large subunit ribosomal protein L13 D Metbo_0785 50S ribosomal protein L14P K02874 RP-L14; large subunit ribosomal protein L14 D Metbo_0797 50S ribosomal protein L15P K02876 RP-L15; large subunit ribosomal protein L15 D Metbo_0794 ribosomal protein L18P/L5E K02881 RP-L18; large subunit ribosomal protein L18 D Metbo_0779 ribosomal protein L22 K02890 RP-L22; large subunit ribosomal protein L22 D Metbo_0776 ribosomal protein L23 K02892 RP-L23; large subunit ribosomal protein L23 D Metbo_0786 ribosomal protein L24 K02895 RP-L24; large subunit ribosomal protein L24 D Metbo_0781 ribosomal protein L29 K02904 RP-L29; large subunit ribosomal protein L29 D Metbo_0796 ribosomal protein L30P K02907 RP-L30; large subunit ribosomal protein L30 D Metbo_2253 50S ribosomal protein L12P K02869 RP-L12; large subunit ribosomal protein L12 D Metbo_0546 50S ribosomal protein LX K02944 RP-LX; large subunit ribosomal protein LX D Metbo_R0022 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D Metbo_R0023 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D Metbo_R0030 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D Metbo_R0019 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D Metbo_R0033 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D Metbo_R0021 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D Metbo_R0031 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA C 03009 Ribosome biogenesis [BR:mel03009] D Metbo_0306 Pre-mRNA processing ribonucleoprotein, binding domain protein K14564 NOP56; nucleolar protein 56 D Metbo_0210 Ribosome biogenesis protein Nop10 K11130 NOP10; H/ACA ribonucleoprotein complex subunit 3 D Metbo_2181 Brix domain protein K14561 IMP4; U3 small nucleolar ribonucleoprotein protein IMP4 D Metbo_2373 KH domain protein K06961 KRR1; ribosomal RNA assembly protein D Metbo_2372 Non-specific serine/threonine protein kinase K07178 RIOK1; RIO kinase 1 [EC:2.7.11.1] D Metbo_0537 adenylate kinase K18532 AK6; adenylate kinase [EC:2.7.4.3] D Metbo_2271 UPF0293 protein K09140 TSR3; rRNA small subunit aminocarboxypropyltransferase [EC:2.5.1.157] D Metbo_0592 ABC transporter related protein K06174 ABCE1; ATP-binding cassette, sub-family E, member 1 D Metbo_1962 small GTP-binding protein K06943 NOG1; nucleolar GTP-binding protein D Metbo_0783 Ribonuclease P protein component 1 K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5] D Metbo_2189 Ribonuclease P protein component 2 K03537 POP5; ribonuclease P/MRP protein subunit POP5 [EC:3.1.26.5] D Metbo_2190 Ribonuclease P protein component 3 K03539 RPP1; ribonuclease P/MRP protein subunit RPP1 [EC:3.1.26.5] D Metbo_0545 Translation initiation factor 6 K03264 EIF6; translation initiation factor 6 D Metbo_0527 NMD3 family protein K07562 NMD3; 60S ribosomal export protein NMD3 D Metbo_2187 Shwachman-Bodian-Diamond syndrome protein K14574 SDO1; ribosome maturation protein SDO1 D Metbo_2064 AAA family ATPase, CDC48 subfamily K13525 VCP; transitional endoplasmic reticulum ATPase D Metbo_0737 GTP-binding protein HSR1-related protein K03595 era; GTPase D Metbo_0305 Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase K04795 flpA; fibrillarin-like pre-rRNA processing protein D Metbo_0611 50S ribosomal protein L7Ae K02936 RP-L7Ae; large subunit ribosomal protein L7Ae D Metbo_2335 H/ACA RNA-protein complex component Gar1 K07569 gar1; RNA-binding protein D Metbo_2393 NusA family KH domain protein K02600 nusA; transcription termination/antitermination protein NusA D Metbo_0191 Ribosomal RNA small subunit methyltransferase A K02528 ksgA; 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase [EC:2.1.1.182] D Metbo_0531 Ribosomal RNA large subunit methyltransferase E K02427 rlmE; 23S rRNA (uridine2552-2'-O)-methyltransferase [EC:2.1.1.166] D Metbo_2226 ribosomal-protein-alanine acetyltransferase K03789 rimI; [ribosomal protein S18]-alanine N-acetyltransferase [EC:2.3.1.266] D Metbo_2205 DEAD/DEAH box helicase domain protein K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7] D Metbo_0587 Sua5/YciO/YrdC/YwlC family protein K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87] D Metbo_0539 protein of unknown function UPF0044 K07574 yhbY; RNA-binding protein D Metbo_0024 GTPase of unknown function domain protein K06942 ychF; ribosome-binding ATPase C 03016 Transfer RNA biogenesis [BR:mel03016] D Metbo_0783 Ribonuclease P protein component 1 K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5] D Metbo_2189 Ribonuclease P protein component 2 K03537 POP5; ribonuclease P/MRP protein subunit POP5 [EC:3.1.26.5] D Metbo_2190 Ribonuclease P protein component 3 K03539 RPP1; ribonuclease P/MRP protein subunit RPP1 [EC:3.1.26.5] D Metbo_0538 Ribonuclease P protein component 4 K03540 RPR2; ribonuclease P protein subunit RPR2 [EC:3.1.26.5] D Metbo_0645 Ribonuclease Z K00784 rnz; ribonuclease Z [EC:3.1.26.11] D Metbo_0556 protein of unknown function UPF0027 K14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8] D Metbo_0560 protein of unknown function DUF101 K24956 ZBTB8OS; protein archease D Metbo_0339 protein synthesis factor GTP-binding protein K03231 EEF1A; elongation factor 1-alpha D Metbo_2389 translation elongation factor EF-1, subunit alpha K03231 EEF1A; elongation factor 1-alpha D Metbo_0823 glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D Metbo_1014 Prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15] D Metbo_0154 Isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5] D Metbo_0017 leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D Metbo_1344 Methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] D Metbo_0089 Arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D Metbo_2254 alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7] D Metbo_0661 glycyl-tRNA synthetase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14] D Metbo_0086 threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3] D Metbo_2230 Seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11] D Metbo_1210 cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16] D Metbo_0943 Valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9] D Metbo_0622 ATP phosphoribosyltransferase regulatory subunit K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21] D Metbo_1081 Phenylalanyl-tRNA synthetase alpha chain K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20] D Metbo_0950 Phenylalanyl-tRNA synthetase beta chain K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20] D Metbo_0526 Tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D Metbo_0615 tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2] D Metbo_1941 RNA modification enzyme, MiaB family K15865 CDKAL1; threonylcarbamoyladenosine tRNA methylthiotransferase CDKAL1 [EC:2.8.4.5] D Metbo_0334 N(2),N(2)-dimethylguanosine tRNA methyltransferase K00555 TRMT1; tRNA (guanine26-N2/guanine27-N2)-dimethyltransferase [EC:2.1.1.215 2.1.1.216] D Metbo_0692 protein of unknown function Met10 K15429 TRM5; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228] D Metbo_0108 tRNA (adenine-N(1)-)-methyltransferase K07442 TRM61; tRNA (adenine57-N1/adenine58-N1)-methyltransferase catalytic subunit [EC:2.1.1.219 2.1.1.220] D Metbo_2486 Uncharacterized protein family UPF0066 K22900 TRMO; tRNA (adenine37-N6)-methyltransferase [EC:2.1.1.-] D Metbo_2402 Wyosine base formation domain-containing protein K15449 TYW1; tRNA wybutosine-synthesizing protein 1 [EC:4.1.3.44] D Metbo_0325 protein of unknown function Met10 K07055 TRM12; tRNA wybutosine-synthesizing protein 2 [EC:2.5.1.114] D Metbo_1952 tRNA pseudouridine synthase A K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12] D Metbo_0804 tRNA pseudouridine synthase B K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25] D Metbo_0011 tRNA pseudouridine synthase D K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27] D Metbo_0195 Conserved hypothetical protein CHP01213 K07583 PUS10; tRNA pseudouridine synthase 10 [EC:5.4.99.25] D Metbo_1214 Cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D Metbo_1848 Cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D Metbo_1926 histone acetyltransferase, ELP3 family K07739 ELP3; elongator complex protein 3 (tRNA carboxymethyluridine synthase) [EC:2.3.1.311] D Metbo_0587 Sua5/YciO/YrdC/YwlC family protein K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87] D Metbo_0420 protein of unknown function DUF549 K10761 THG1; tRNA(His) guanylyltransferase [EC:2.7.7.79] D Metbo_R0008 rnpB; RNA component of RNaseP K01978 rnpB; M1 RNA D Metbo_0623 UPF0278 protein K09006 K09006; RNA-free ribonuclease P [EC:3.1.26.5] D Metbo_1357 CCA-adding enzyme K07558 K07558; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72] D Metbo_0616 tRNA-splicing endonuclease K01170 endA; tRNA-intron endonuclease, archaea type [EC:4.6.1.16] D Metbo_1358 2'-5' RNA ligase K01975 thpR; RNA 2',3'-cyclic 3'-phosphodiesterase [EC:3.1.4.58] D Metbo_2526 Lysyl-tRNA synthetase K04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6] D Metbo_1366 aspartyl-tRNA synthetase K09759 aspC; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23] D Metbo_0044 O-phosphoseryl-tRNA(Cys) synthetase K07587 sepRS; O-phosphoseryl-tRNA synthetase [EC:6.1.1.27] D Metbo_2382 O-phospho-L-seryl-tRNA:Cys-tRNA synthase K06868 sepcysS; Sep-tRNA:Cys-tRNA synthetase [EC:2.5.1.73] D Metbo_0550 Methyltransferase type 12 K15256 cmoA; tRNA (cmo5U34)-methyltransferase [EC:2.1.1.-] D Metbo_1537 Methyltransferase type 12 K15256 cmoA; tRNA (cmo5U34)-methyltransferase [EC:2.1.1.-] D Metbo_2365 Conserved hypothetical protein CHP01177 K07446 trm-G10; tRNA (guanine10-N2)-dimethyltransferase [EC:2.1.1.213] D Metbo_0385 tRNA ribose 2'-O-methyltransferase aTrm56 K07254 atrm56; tRNA (cytidine56-2'-O)-methyltransferase [EC:2.1.1.206] D Metbo_1850 SirA-like domain-containing protein K04085 tusA; tRNA 2-thiouridine synthesizing protein A [EC:2.8.1.-] D Metbo_0101 O-sialoglycoprotein endopeptidase K15904 kae1-bud32; bifunctional N6-L-threonylcarbamoyladenine synthase / protein kinase Bud32 [EC:2.3.1.234 2.7.11.1] D Metbo_2362 hypothetical protein K09119 cgi121; KEOPS complex subunit Cgi121 D Metbo_2180 hypothetical protein K09741 pcc1; KEOPS complex subunit Pcc1 D Metbo_0392 exsB protein K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20] D Metbo_0292 6-pyruvoyltetrahydropterin synthase K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50] D Metbo_0293 Radical SAM domain protein K10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3] D Metbo_0712 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein K18979 queG; epoxyqueuosine reductase [EC:1.17.99.6] D Metbo_1655 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein K18979 queG; epoxyqueuosine reductase [EC:1.17.99.6] D Metbo_1686 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein K18979 queG; epoxyqueuosine reductase [EC:1.17.99.6] D Metbo_0233 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein K18979 queG; epoxyqueuosine reductase [EC:1.17.99.6] D Metbo_1252 hypothetical protein K18979 queG; epoxyqueuosine reductase [EC:1.17.99.6] D Metbo_0966 7-cyano-7-deazaguanine tRNA-ribosyltransferase K18779 tgtA; 7-cyano-7-deazaguanine tRNA-ribosyltransferase [EC:2.4.2.48] D Metbo_1266 tRNA sulfurtransferase K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4] D Metbo_0426 domain of unknown function DUF1743 K06932 tiaS; tRNA(Ile2)-agmatinylcytidine synthase [EC:6.3.4.22] C 03012 Translation factors [BR:mel03012] D Metbo_2371 Translation initiation factor 1A K03236 EIF1A; translation initiation factor 1A D Metbo_0782 Translation factor SUI1-like protein K03113 EIF1; translation initiation factor 1 D Metbo_0209 Translation initiation factor 2 subunit alpha K03237 EIF2S1; translation initiation factor 2 subunit 1 D Metbo_0528 Translation initiation factor 2 subunit beta K03238 EIF2S2; translation initiation factor 2 subunit 2 D Metbo_0605 Translation initiation factor 2 subunit gamma K03242 EIF2S3; translation initiation factor 2 subunit 3 D Metbo_2348 Translation initiation factor 5A K03263 EIF5A; translation initiation factor 5A D Metbo_0607 translation initiation factor aIF-2 K03243 EIF5B; translation initiation factor 5B D Metbo_0545 Translation initiation factor 6 K03264 EIF6; translation initiation factor 6 D Metbo_0339 protein synthesis factor GTP-binding protein K03231 EEF1A; elongation factor 1-alpha D Metbo_2389 translation elongation factor EF-1, subunit alpha K03231 EEF1A; elongation factor 1-alpha D Metbo_0403 Elongation factor 1-beta K03232 EEF1B; elongation factor 1-beta D Metbo_2390 translation elongation factor aEF-2 K03234 EEF2; elongation factor 2 D Metbo_0198 universal diphthamide biosynthesis domain-containing protein K07561 DPH1; 2-(3-amino-3-carboxypropyl)histidine synthase [EC:2.5.1.108] D Metbo_1158 universal metal-binding-domain/4Fe-4S-binding-domain containing ABC transporter protein K06927 DPH6; diphthine-ammonia ligase [EC:6.3.1.14] D Metbo_2339 Peptide chain release factor subunit 1 K03265 ETF1; peptide chain release factor subunit 1 D Metbo_0188 methylase K02493 hemK; release factor glutamine methyltransferase [EC:2.1.1.297] D Metbo_0406 Peptidyl-tRNA hydrolase K04794 PTH2; peptidyl-tRNA hydrolase, PTH2 family [EC:3.1.1.29] C 03110 Chaperones and folding catalysts [BR:mel03110] D Metbo_0229 Chaperone protein dnaK K04043 dnaK; molecular chaperone DnaK D Metbo_1901 thermosome K22447 cct; archaeal chaperonin D Metbo_1370 thermosome K22447 cct; archaeal chaperonin D Metbo_0228 Chaperone protein dnaJ K03686 dnaJ; molecular chaperone DnaJ D Metbo_0230 Protein grpE K03687 GRPE; molecular chaperone GrpE D Metbo_0945 heat shock protein Hsp20 K13993 HSP20; HSP20 family protein D Metbo_1822 heat shock protein Hsp20 K13993 HSP20; HSP20 family protein D Metbo_1961 heat shock protein Hsp20 K13993 HSP20; HSP20 family protein D Metbo_1041 heat shock protein Hsp20 K13993 HSP20; HSP20 family protein D Metbo_1027 heat shock protein Hsp20 K13993 HSP20; HSP20 family protein D Metbo_1229 hypothetical protein K13993 HSP20; HSP20 family protein D Metbo_1295 heat shock protein Hsp20 K13993 HSP20; HSP20 family protein D Metbo_0547 Prefoldin subunit alpha K04797 pfdA; prefoldin alpha subunit D Metbo_2179 Prefoldin subunit beta K04798 pfdB; prefoldin beta subunit D Metbo_2202 hydrogenase nickel incorporation protein hypA K04651 hypA; hydrogenase nickel incorporation protein HypA/HybF D Metbo_2201 hydrogenase accessory protein HypB K04652 hypB; hydrogenase nickel incorporation protein HypB D Metbo_0121 peptidyl-prolyl cis-trans isomerase cyclophilin type K03768 PPIB; peptidyl-prolyl cis-trans isomerase B (cyclophilin B) [EC:5.2.1.8] D Metbo_0375 peptidylprolyl isomerase FKBP-type K03775 slyD; FKBP-type peptidyl-prolyl cis-trans isomerase SlyD [EC:5.2.1.8] D Metbo_0496 Thioredoxin domain-containing protein K03671 TXN; thioredoxin D Metbo_1912 redox-active disulfide protein 1 K03671 TXN; thioredoxin C 04131 Membrane trafficking [BR:mel04131] D Metbo_0608 Nucleoside diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6] D Metbo_2064 AAA family ATPase, CDC48 subfamily K13525 VCP; transitional endoplasmic reticulum ATPase D Metbo_0020 arsenite-activated ATPase ArsA K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-] D Metbo_2248 Preprotein translocase subunit secE K07342 SEC61G; protein transport protein SEC61 subunit gamma and related proteins D Metbo_0339 protein synthesis factor GTP-binding protein K03231 EEF1A; elongation factor 1-alpha D Metbo_2389 translation elongation factor EF-1, subunit alpha K03231 EEF1A; elongation factor 1-alpha C 04121 Ubiquitin system [BR:mel04121] D Metbo_2270 50S ribosomal protein L40e K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e D Metbo_0598 30S ribosomal protein S27ae K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae D Metbo_1939 hypothetical protein K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae C 03051 Proteasome [BR:mel03051] D Metbo_2188 Proteasome subunit alpha K03432 psmA; proteasome alpha subunit [EC:3.4.25.1] D Metbo_0323 proteasome endopeptidase complex, beta subunit K03433 psmB; proteasome beta subunit [EC:3.4.25.1] D Metbo_2222 Proteasome-activating nucleotidase K03420 psmR; proteasome regulatory subunit C 03032 DNA replication proteins [BR:mel03032] D Metbo_0167 Replication factor-A domain protein K07466 RFA1; replication factor A1 D Metbo_0205 DNA polymerase sliding clamp K04802 PCNA; proliferating cell nuclear antigen D Metbo_2068 Flap structure-specific endonuclease K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-] D Metbo_2463 DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7] D Metbo_0210 Ribosome biogenesis protein Nop10 K11130 NOP10; H/ACA ribonucleoprotein complex subunit 3 D Metbo_2330 UPF0095 protein K02316 dnaG; DNA primase [EC:2.7.7.101] D Metbo_0110 Cell division control protein 6-like protein K10725 cdc6A; archaeal cell division control protein 6 D Metbo_0562 Cell division control protein 6-like protein K10725 cdc6A; archaeal cell division control protein 6 D Metbo_0529 MCM family protein K10726 mcm; replicative DNA helicase Mcm [EC:5.6.2.3] D Metbo_1347 DNA primase small subunit K02683 priS; DNA primase small subunit [EC:2.7.7.102] D Metbo_1346 DNA primase, large subunit K18882 priL; DNA primase large subunit D Metbo_0206 hypothetical protein K09723 ginS; DNA replication factor GINS D Metbo_2431 ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4] D Metbo_0236 DNA polymerase B region K02319 pol; DNA polymerase, archaea type [EC:2.7.7.7] D Metbo_2171 DNA-directed DNA polymerase K02319 pol; DNA polymerase, archaea type [EC:2.7.7.7] D Metbo_1576 DNA polymerase B exonuclease K02319 pol; DNA polymerase, archaea type [EC:2.7.7.7] D Metbo_2532 DNA polymerase II large subunit K02322 polC; DNA polymerase II large subunit [EC:2.7.7.7] D Metbo_0115 DNA-directed DNA polymerase K02323 polB; DNA polymerase II small subunit [EC:2.7.7.7] D Metbo_0636 Replication factor C large subunit K04800 rfcL; replication factor C large subunit D Metbo_0637 Replication factor C small subunit K04801 rfcS; replication factor C small subunit D Metbo_0694 DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72] D Metbo_2375 Type 2 DNA topoisomerase 6 subunit A K03166 top6A; DNA topoisomerase VI subunit A [EC:5.6.2.2] D Metbo_2374 DNA topoisomerase VI, B subunit K03167 top6B; DNA topoisomerase VI subunit B [EC:5.6.2.2] D Metbo_0533 DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1] C 03036 Chromosome and associated proteins [BR:mel03036] D Metbo_0773 protein of unknown function DUF171 K09142 SPOUT1; methyltransferase [EC:2.1.1.-] D Metbo_0593 Transcription factor CBF/NF-Y/histone domain-containing protein K24450 hmf; DNA-binding protein D Metbo_0612 Transcription factor CBF/NF-Y/histone domain-containing protein K24450 hmf; DNA-binding protein D Metbo_1932 Transcription factor CBF/NF-Y/histone domain-containing protein K24450 hmf; DNA-binding protein D Metbo_2247 cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ D Metbo_0657 cell division ATPase MinD K03609 minD; septum site-determining protein MinD D Metbo_0656 cell division ATPase MinD K03609 minD; septum site-determining protein MinD D Metbo_2430 cell shape determining protein MreB/Mrl K03569 mreB; rod shape-determining protein MreB and related proteins D Metbo_0085 Cobyrinic acid ac-diamide synthase K03496 parA; chromosome partitioning protein D Metbo_0826 Cobyrinic acid ac-diamide synthase K03496 parA; chromosome partitioning protein D Metbo_1785 Cobyrinic acid ac-diamide synthase K03496 parA; chromosome partitioning protein D Metbo_2328 Tyrosine recombinase xerC K04763 xerD; integrase/recombinase XerD D Metbo_1498 ATPase-like, ParA/MinD K03593 mrp; ATP-binding protein involved in chromosome partitioning D Metbo_1606 filamentation induced by cAMP protein Fic K04095 fic; cell filamentation protein, protein adenylyltransferase [EC:2.7.7.108] C 03400 DNA repair and recombination proteins [BR:mel03400] D Metbo_0469 methylated-DNA/protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63] D Metbo_1383 methylated-DNA/protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63] D Metbo_0128 3-methyladenine DNA glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21] D Metbo_0125 DNA-(apurinic or apyrimidinic site) lyase K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18] D Metbo_0940 DNA-(apurinic or apyrimidinic site) lyase K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] D Metbo_0205 DNA polymerase sliding clamp K04802 PCNA; proliferating cell nuclear antigen D Metbo_2068 Flap structure-specific endonuclease K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-] D Metbo_2463 DNA ligase K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7] D Metbo_0167 Replication factor-A domain protein K07466 RFA1; replication factor A1 D Metbo_1987 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D Metbo_0202 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D Metbo_0551 dUTP diphosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23] D Metbo_0710 HhH-GPD family protein K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21] D Metbo_0129 DNA-3-methyladenine glycosylase I K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20] D Metbo_2449 exodeoxyribonuclease III Xth K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2] D Metbo_2445 Xylose isomerase domain-containing protein TIM barrel K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2] D Metbo_0104 phosphoesterase RecJ domain protein K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D Metbo_2120 phosphoesterase DHHA1 K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D Metbo_1103 UvrABC system protein A K03701 uvrA; excinuclease ABC subunit A D Metbo_1104 UvrABC system protein B K03702 uvrB; excinuclease ABC subunit B D Metbo_1143 UvrABC system protein C K03703 uvrC; excinuclease ABC subunit C D Metbo_1642 UvrD/REP helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] D Metbo_1561 UvrD/REP helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] D Metbo_0512 DNA mismatch repair protein MutS domain protein K07456 mutS2; DNA mismatch repair protein MutS2 D Metbo_0694 DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72] D Metbo_2076 SMC domain protein K03546 sbcC; DNA repair protein SbcC/Rad50 D Metbo_2077 metallophosphoesterase K03547 sbcD; DNA repair protein SbcD/Mre11 D Metbo_1117 putative transcriptional regulator K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4] D Metbo_0166 DNA repair and recombination protein radA K04483 radA; DNA repair protein RadA D Metbo_0588 DNA repair and recombination protein radB K04484 radB; DNA repair protein RadB D Metbo_0311 Resolvase, Holliday junction-type K03552 hjr; holliday junction resolvase [EC:3.1.21.10] D Metbo_2078 protein of unknown function DUF87 K06915 herA; DNA double-strand break repair helicase HerA and related ATPase D Metbo_2079 NurA domain-containing protein K25510 nurA; DNA double-strand break repair nuclease NurA [EC:3.1.-.-] D Metbo_1915 DEAD/DEAH box helicase domain protein K03726 helS; ATP-dependent DNA helicase [EC:5.6.2.4] D Metbo_2386 Ku domain protein K10979 ku; DNA end-binding protein Ku D Metbo_0533 DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1] D Metbo_1419 PHP domain protein K02347 polX; DNA polymerase (family X) D Metbo_0134 type III restriction protein res subunit K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3] D Metbo_1873 DEAD/H associated domain protein K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4] D Metbo_2360 protein of unknown function DUF650 K22585 nreA; DNA repair protein NreA C 03029 Mitochondrial biogenesis [BR:mel03029] D Metbo_0783 Ribonuclease P protein component 1 K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5] D Metbo_2189 Ribonuclease P protein component 2 K03537 POP5; ribonuclease P/MRP protein subunit POP5 [EC:3.1.26.5] D Metbo_2190 Ribonuclease P protein component 3 K03539 RPP1; ribonuclease P/MRP protein subunit RPP1 [EC:3.1.26.5] D Metbo_0737 GTP-binding protein HSR1-related protein K03595 era; GTPase D Metbo_0526 Tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D Metbo_0017 leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D Metbo_0661 glycyl-tRNA synthetase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14] D Metbo_0089 Arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D Metbo_0049 Glutamyl-tRNA(Gln) amidotransferase subunit A K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7] D Metbo_0314 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7] D Metbo_0229 Chaperone protein dnaK K04043 dnaK; molecular chaperone DnaK D Metbo_0230 Protein grpE K03687 GRPE; molecular chaperone GrpE D Metbo_0228 Chaperone protein dnaJ K03686 dnaJ; molecular chaperone DnaJ D Metbo_1214 Cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D Metbo_1848 Cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D Metbo_1498 ATPase-like, ParA/MinD K03593 mrp; ATP-binding protein involved in chromosome partitioning B B 09183 Protein families: signaling and cellular processes C 02000 Transporters [BR:mel02000] D Metbo_0851 Xenobiotic-transporting ATPase K06148 ABCC-BAC; ATP-binding cassette, subfamily C, bacterial D Metbo_2504 extracellular solute-binding protein family 1 K15495 wtpA; molybdate/tungstate transport system substrate-binding protein D Metbo_1093 ABC-type transporter, integral membrane subunit K15496 wtpB; molybdate/tungstate transport system permease protein D Metbo_1092 Polyamine-transporting ATPase K15497 wtpC; molybdate/tungstate transport system ATP-binding protein [EC:7.3.2.5 7.3.2.6] D Metbo_1662 aliphatic sulfonates family ABC transporter, periplasmic ligand-binding protein K15553 ssuA; sulfonate transport system substrate-binding protein D Metbo_1889 ABC-type transporter, periplasmic subunit family 3 K15553 ssuA; sulfonate transport system substrate-binding protein D Metbo_1661 ABC-type transporter, integral membrane subunit K15554 ssuC; sulfonate transport system permease protein D Metbo_1660 Taurine-transporting ATPase K15555 ssuB; sulfonate transport system ATP-binding protein [EC:7.6.2.14] D Metbo_1200 putative ABC transporter K02051 ABC.SN.S; NitT/TauT family transport system substrate-binding protein D Metbo_0477 phosphate binding protein K02040 pstS; phosphate transport system substrate-binding protein D Metbo_1594 phosphate binding protein K02040 pstS; phosphate transport system substrate-binding protein D Metbo_0478 phosphate ABC transporter, inner membrane subunit PstC K02037 pstC; phosphate transport system permease protein D Metbo_0479 phosphate ABC transporter, inner membrane subunit PstA K02038 pstA; phosphate transport system permease protein D Metbo_0480 phosphate ABC transporter, ATPase subunit K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1] D Metbo_2490 ABC-type transporter, periplasmic subunit K02016 ABC.FEV.S; iron complex transport system substrate-binding protein D Metbo_2480 ABC-type transporter, periplasmic subunit K02016 ABC.FEV.S; iron complex transport system substrate-binding protein D Metbo_2489 ABC-type transporter, integral membrane subunit K02015 ABC.FEV.P; iron complex transport system permease protein D Metbo_2488 Iron-chelate-transporting ATPase K02013 ABC.FEV.A; iron complex transport system ATP-binding protein [EC:7.2.2.-] D Metbo_1702 ABC-type metal ion transporter, periplasmic subunit K09815 znuA; zinc transport system substrate-binding protein D Metbo_1704 ABC-type transporter, integral membrane subunit K09816 znuB; zinc transport system permease protein D Metbo_1703 Phosphonate-transporting ATPase K09817 znuC; zinc transport system ATP-binding protein [EC:7.2.2.20] D Metbo_0753 cobalt transport protein K02009 cbiN; cobalt/nickel transport protein D Metbo_0073 cobalt transport protein CbiN K02009 cbiN; cobalt/nickel transport protein D Metbo_0074 cobalt ABC transporter, inner membrane subunit CbiQ K02008 cbiQ; cobalt/nickel transport system permease protein D Metbo_0754 cobalt ABC transporter, inner membrane subunit CbiQ K02008 cbiQ; cobalt/nickel transport system permease protein D Metbo_0072 cobalamin (vitamin B12) biosynthesis CbiM protein K02007 cbiM; cobalt/nickel transport system permease protein D Metbo_0752 cobalamin biosynthesis protein CbiM K02007 cbiM; cobalt/nickel transport system permease protein D Metbo_1971 cobalt ABC transporter, ATPase subunit K02006 cbiO; cobalt/nickel transport system ATP-binding protein D Metbo_2326 BioY protein K03523 bioY; biotin transport system substrate-specific component D Metbo_0902 ABC-2 type transporter K09690 wzm; homopolymeric O-antigen transport system permease protein D Metbo_0901 Teichoic-acid-transporting ATPase K09691 wzt; homopolymeric O-antigen transport system ATP-binding protein [EC:7.5.2.14] D Metbo_0151 ABC-2 type transporter K01992 ABC-2.P; ABC-2 type transport system permease protein D Metbo_0061 ABC-2 type transporter K01992 ABC-2.P; ABC-2 type transport system permease protein D Metbo_0452 daunorubicin resistance ABC transporter, inner membrane subunit B K01992 ABC-2.P; ABC-2 type transport system permease protein D Metbo_0697 ABC-2 type transporter K01992 ABC-2.P; ABC-2 type transport system permease protein D Metbo_1313 ABC-2 type transporter K01992 ABC-2.P; ABC-2 type transport system permease protein D Metbo_1476 ABC-2 type transporter K01992 ABC-2.P; ABC-2 type transport system permease protein D Metbo_1877 ABC-2 type transporter K01992 ABC-2.P; ABC-2 type transport system permease protein D Metbo_2057 ABC-2 type transporter K01992 ABC-2.P; ABC-2 type transport system permease protein D Metbo_0150 ABC-2 type transporter K01992 ABC-2.P; ABC-2 type transport system permease protein D Metbo_1460 ABC-2 type transporter K01992 ABC-2.P; ABC-2 type transport system permease protein D Metbo_1058 putative ABC-type transport system, permease component K01992 ABC-2.P; ABC-2 type transport system permease protein D Metbo_2056 Sulfate-transporting ATPase K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D Metbo_0060 daunorubicin resistance ABC transporter ATPase subunit K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D Metbo_0149 Fe(3+)-transporting ATPase K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D Metbo_0453 daunorubicin resistance ABC transporter ATPase subunit K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D Metbo_0696 Sulfate-transporting ATPase K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D Metbo_1059 Phosphonate-transporting ATPase K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D Metbo_1312 Sulfate-transporting ATPase K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D Metbo_1475 daunorubicin resistance ABC transporter ATPase subunit K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D Metbo_1876 daunorubicin resistance ABC transporter ATPase subunit K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D Metbo_1824 protein of unknown function DUF214 K02004 ABC.CD.P; putative ABC transport system permease protein D Metbo_1800 protein of unknown function DUF214 K02004 ABC.CD.P; putative ABC transport system permease protein D Metbo_1254 protein of unknown function DUF214 K02004 ABC.CD.P; putative ABC transport system permease protein D Metbo_1588 protein of unknown function DUF214 K02004 ABC.CD.P; putative ABC transport system permease protein D Metbo_1515 protein of unknown function DUF214 K02004 ABC.CD.P; putative ABC transport system permease protein D Metbo_1488 protein of unknown function DUF214 K02004 ABC.CD.P; putative ABC transport system permease protein D Metbo_2165 protein of unknown function DUF214 K02004 ABC.CD.P; putative ABC transport system permease protein D Metbo_1825 Phosphonate-transporting ATPase K02003 ABC.CD.A; putative ABC transport system ATP-binding protein D Metbo_1253 Phosphonate-transporting ATPase K02003 ABC.CD.A; putative ABC transport system ATP-binding protein D Metbo_1587 Phosphonate-transporting ATPase K02003 ABC.CD.A; putative ABC transport system ATP-binding protein D Metbo_1516 Phosphonate-transporting ATPase K02003 ABC.CD.A; putative ABC transport system ATP-binding protein D Metbo_2166 ABC transporter related protein K02003 ABC.CD.A; putative ABC transport system ATP-binding protein D Metbo_0367 ABC transporter related protein K09013 sufC; Fe-S cluster assembly ATP-binding protein D Metbo_1425 sodium/hydrogen exchanger K23994 SLC9B1_2; solute carrier family 9B (sodium/hydrogen exchanger), member 1/2 D Metbo_1086 anion transporter K14445 SLC13A2_3_5; solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2/3/5 D Metbo_0362 anion transporter K14445 SLC13A2_3_5; solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2/3/5 D Metbo_0451 anion transporter K14445 SLC13A2_3_5; solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2/3/5 D Metbo_0501 MATE efflux family protein K26937 dinF; MATE family, multidrug efflux pump D Metbo_1520 MATE efflux family protein K26937 dinF; MATE family, multidrug efflux pump D Metbo_2087 major facilitator superfamily MFS_1 K08221 yitG; MFS transporter, ACDE family, multidrug resistance protein D Metbo_1056 major facilitator superfamily MFS_1 K08224 ynfM; MFS transporter, YNFM family, putative membrane transport protein D Metbo_1426 MIP family channel protein K02440 glpF; glycerol uptake facilitator D Metbo_1735 Ion transport 2 domain protein K10716 kch; voltage-gated potassium channel D Metbo_0767 Ion transport 2 domain protein K10716 kch; voltage-gated potassium channel D Metbo_1643 Ion transport 2 domain protein K10716 kch; voltage-gated potassium channel D Metbo_1854 Ion transport 2 domain protein K10716 kch; voltage-gated potassium channel D Metbo_0253 TrkA-N domain protein K10716 kch; voltage-gated potassium channel D Metbo_0572 ammonium transporter K03320 amt; ammonium transporter, Amt family D Metbo_0570 ammonium transporter K03320 amt; ammonium transporter, Amt family D Metbo_0644 MscS Mechanosensitive ion channel K03442 mscS; small conductance mechanosensitive channel D Metbo_0186 MgtE intracellular region K06213 mgtE; magnesium transporter D Metbo_2432 MotA/TolQ/ExbB proton channel K03561 exbB; biopolymer transport protein ExbB D Metbo_2433 Biopolymer transport protein ExbD/TolR K03559 exbD; biopolymer transport protein ExbD D Metbo_0055 protein of unknown function DUF1211 K24915 TMEM175; TMEM175 potassium channel family protein D Metbo_1723 protein of unknown function DUF1211 K24915 TMEM175; TMEM175 potassium channel family protein D Metbo_0286 protein of unknown function DUF1211 K24915 TMEM175; TMEM175 potassium channel family protein D Metbo_1511 conserved repeat domain protein K07279 yfaL; autotransporter family porin D Metbo_0848 conserved repeat domain protein K21449 ata; trimeric autotransporter adhesin D Metbo_1958 polymorphic outer membrane protein K21449 ata; trimeric autotransporter adhesin D Metbo_2367 UPF0060 membrane protein ynfA K09771 TC.SMR3; small multidrug resistance family-3 protein D Metbo_0953 Na+/Ca+ antiporter, CaCA family K07301 yrbG; cation:H+ antiporter D Metbo_1596 sodium/hydrogen exchanger K24160 NHA1; sodium/hydrogen antiporter D Metbo_1720 sodium/hydrogen exchanger K11105 cvrA; potassium/hydrogen antiporter D Metbo_1034 cation transporter K03498 trkH; trk/ktr system potassium uptake protein D Metbo_0244 potassium uptake protein, TrkH family K03498 trkH; trk/ktr system potassium uptake protein D Metbo_0243 TrkA-N domain protein K03499 trkA; trk/ktr system potassium uptake protein D Metbo_2208 TrkA-N domain protein K03499 trkA; trk/ktr system potassium uptake protein D Metbo_1035 TrkA-N domain protein K03499 trkA; trk/ktr system potassium uptake protein D Metbo_1036 TrkA-N domain protein K03499 trkA; trk/ktr system potassium uptake protein D Metbo_1385 Xanthine/uracil/vitamin C permease K06901 pbuG; adenine/guanine/hypoxanthine permease D Metbo_1597 Cl-channel voltage-gated family protein K03281 clcA; chloride channel protein, CIC family D Metbo_0020 arsenite-activated ATPase ArsA K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-] D Metbo_1862 arsenical-resistance protein K03325 ACR3; arsenite transporter D Metbo_1956 polysaccharide biosynthesis protein K06409 spoVB; stage V sporulation protein B D Metbo_0568 polysaccharide biosynthesis protein K06409 spoVB; stage V sporulation protein B D Metbo_0165 Auxin Efflux Carrier K24180 mleP; malate permease and related proteins D Metbo_1748 MtN3 and saliva related transmembrane protein K15383 K15383; MtN3 and saliva related transmembrane protein D Metbo_1029 ferrous iron transport protein B K04759 feoB; ferrous iron transport protein B D Metbo_0455 TspO and MBR like protein K05770 TSPO; translocator protein D Metbo_1829 TspO and MBR like protein K05770 TSPO; translocator protein C 02044 Secretion system [BR:mel02044] D Metbo_0460 type II secretion system protein E K07332 flaI; archaeal flagellar protein FlaI D Metbo_0461 Type II secretion system F domain protein K07333 flaJ; archaeal flagellar protein FlaJ D Metbo_0413 Type II secretion system F domain protein K07333 flaJ; archaeal flagellar protein FlaJ D Metbo_1168 Peptidase A24A domain protein K07991 flaK; archaeal preflagellin peptidase FlaK [EC:3.4.23.52] D Metbo_1511 conserved repeat domain protein K07279 yfaL; autotransporter family porin D Metbo_0954 Preprotein translocase, SecD/SecF/SecDF K03072 secD; preprotein translocase subunit SecD D Metbo_0955 Preprotein translocase, SecD/SecF/SecDF K03074 secF; preprotein translocase subunit SecF D Metbo_0798 preprotein translocase, SecY subunit K03076 secY; preprotein translocase subunit SecY D Metbo_0196 Signal recognition 54 kDa protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4] D Metbo_0548 signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor D Metbo_2248 Preprotein translocase subunit secE K07342 SEC61G; protein transport protein SEC61 subunit gamma and related proteins D Metbo_2119 Signal recognition particle 19 kDa protein K03105 SRP19; signal recognition particle subunit SRP19 C 02042 Bacterial toxins C 02022 Two-component system [BR:mel02022] D Metbo_1758 Osmosensitive K channel His kinase sensor K07646 kdpD; two-component system, OmpR family, sensor histidine kinase KdpD [EC:2.7.13.3] D Metbo_1327 MCP methyltransferase/methylesterase, CheR/CheB K13924 cheBR; two-component system, chemotaxis family, CheB/CheR fusion protein [EC:2.1.1.80 3.1.1.61] D Metbo_1666 integral membrane sensor signal transduction histidine kinase K11354 cph1; two-component system, chemotaxis family, sensor kinase Cph1 [EC:2.7.13.3] D Metbo_1775 PAS/PAC sensor signal transduction histidine kinase K11354 cph1; two-component system, chemotaxis family, sensor kinase Cph1 [EC:2.7.13.3] D Metbo_1329 signal transduction histidine kinase K00936 pdtaS; two-component system, sensor histidine kinase PdtaS [EC:2.7.13.3] D Metbo_1823 signal transduction histidine kinase K00936 pdtaS; two-component system, sensor histidine kinase PdtaS [EC:2.7.13.3] D Metbo_1592 response regulator receiver K22010 pdtaR; two-component system, response regulator PdtaR D Metbo_1742 response regulator receiver protein K22010 pdtaR; two-component system, response regulator PdtaR D Metbo_0064 putative PAS/PAC sensor protein K22010 pdtaR; two-component system, response regulator PdtaR D Metbo_0065 putative PAS/PAC sensor protein K22010 pdtaR; two-component system, response regulator PdtaR D Metbo_1223 response regulator receiver protein K22010 pdtaR; two-component system, response regulator PdtaR D Metbo_1351 putative PAS/PAC sensor protein K22010 pdtaR; two-component system, response regulator PdtaR D Metbo_1352 putative PAS/PAC sensor protein K22010 pdtaR; two-component system, response regulator PdtaR D Metbo_1869 response regulator receiver protein K22010 pdtaR; two-component system, response regulator PdtaR C 02035 Bacterial motility proteins [BR:mel02035] D Metbo_2283 MCP methyltransferase, CheR-type K00575 cheR; chemotaxis protein methyltransferase CheR [EC:2.1.1.80] D Metbo_1327 MCP methyltransferase/methylesterase, CheR/CheB K13924 cheBR; two-component system, chemotaxis family, CheB/CheR fusion protein [EC:2.1.1.80 3.1.1.61] D Metbo_0460 type II secretion system protein E K07332 flaI; archaeal flagellar protein FlaI D Metbo_0461 Type II secretion system F domain protein K07333 flaJ; archaeal flagellar protein FlaJ D Metbo_0413 Type II secretion system F domain protein K07333 flaJ; archaeal flagellar protein FlaJ D Metbo_1168 Peptidase A24A domain protein K07991 flaK; archaeal preflagellin peptidase FlaK [EC:3.4.23.52] C 03037 Cilium and associated proteins [BR:mel03037] D Metbo_1425 sodium/hydrogen exchanger K23994 SLC9B1_2; solute carrier family 9B (sodium/hydrogen exchanger), member 1/2 C 04812 Cytoskeleton proteins [BR:mel04812] D Metbo_0817 UPF0103 protein K06990 MEMO1; MEMO1 family protein D Metbo_2430 cell shape determining protein MreB/Mrl K03569 mreB; rod shape-determining protein MreB and related proteins D Metbo_2247 cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ D Metbo_0657 cell division ATPase MinD K03609 minD; septum site-determining protein MinD D Metbo_0656 cell division ATPase MinD K03609 minD; septum site-determining protein MinD D Metbo_0085 Cobyrinic acid ac-diamide synthase K03496 parA; chromosome partitioning protein D Metbo_0826 Cobyrinic acid ac-diamide synthase K03496 parA; chromosome partitioning protein D Metbo_1785 Cobyrinic acid ac-diamide synthase K03496 parA; chromosome partitioning protein C 04147 Exosome [BR:mel04147] D Metbo_0814 Enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D Metbo_2400 Phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3] D Metbo_1003 peroxiredoxin K03386 PRDX2_4; peroxiredoxin 2/4 [EC:1.11.1.24] D Metbo_0339 protein synthesis factor GTP-binding protein K03231 EEF1A; elongation factor 1-alpha D Metbo_2389 translation elongation factor EF-1, subunit alpha K03231 EEF1A; elongation factor 1-alpha D Metbo_2390 translation elongation factor aEF-2 K03234 EEF2; elongation factor 2 D Metbo_0229 Chaperone protein dnaK K04043 dnaK; molecular chaperone DnaK D Metbo_2068 Flap structure-specific endonuclease K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-] D Metbo_0983 inosine-5'-monophosphate dehydrogenase K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205] D Metbo_0598 30S ribosomal protein S27ae K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae D Metbo_1939 hypothetical protein K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae D Metbo_2064 AAA family ATPase, CDC48 subfamily K13525 VCP; transitional endoplasmic reticulum ATPase D Metbo_0278 Long-chain-fatty-acid--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D Metbo_1377 Propanoyl-CoA C-acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] D Metbo_2041 adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3] D Metbo_0799 Adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3] D Metbo_0197 phosphoribosyltransferase K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7] D Metbo_0597 Argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1] D Metbo_0256 Argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5] D Metbo_2484 glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2] D Metbo_1856 Glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D Metbo_1083 Porphobilinogen synthase K01698 hemB; porphobilinogen synthase [EC:4.2.1.24] D Metbo_0422 D-3-phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399] D Metbo_2051 Dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D Metbo_2401 triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] C 02048 Prokaryotic defense system [BR:mel02048] D Metbo_0746 CRISPR locus-related DNA-binding protein K07725 csa3; CRISPR-associated protein Csa3 D Metbo_0287 RecB family exonuclease K07464 cas4; CRISPR-associated exonuclease Cas4 [EC:3.1.12.1] D Metbo_1116 Type I site-specific deoxyribonuclease K01153 hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3] D Metbo_1114 restriction modification system DNA specificity domain protein K01154 hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3] D Metbo_1113 N-6 DNA methylase K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72] D Metbo_0694 DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72] D Metbo_2247 cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ D Metbo_2430 cell shape determining protein MreB/Mrl K03569 mreB; rod shape-determining protein MreB and related proteins D Metbo_0823 glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D Metbo_0681 Nucleotide binding protein PINc K07060 nob1; endoribonuclease Nob1 [EC:3.1.-.-] D Metbo_1214 Cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D Metbo_1848 Cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] C 04030 G protein-coupled receptors C 04050 Cytokine receptors C 04054 Pattern recognition receptors C 03310 Nuclear receptors C 04040 Ion channels [BR:mel04040] C 04031 GTP-binding proteins C 04052 Cytokines and neuropeptides C 04515 Cell adhesion molecules C 04090 CD molecules C 01504 Antimicrobial resistance genes [BR:mel01504] D Metbo_1929 GCN5-related N-acetyltransferase K18815 aac6-I; aminoglycoside 6'-N-acetyltransferase I [EC:2.3.1.82] D Metbo_2132 Chloramphenicol O-acetyltransferase K18234 vat; virginiamycin A acetyltransferase [EC:2.3.1.-] C 00535 Proteoglycans C 00536 Glycosaminoglycan binding proteins C 00537 Glycosylphosphatidylinositol (GPI)-anchored proteins C 04091 Lectins C 04990 Domain-containing proteins not elsewhere classified B B 09185 Viral protein families C 03200 Viral proteins C 03210 Viral fusion proteins B B 09184 RNA family C 03100 Non-coding RNAs [BR:mel03100] D Metbo_R0020 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D Metbo_R0032 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D Metbo_R0042 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D Metbo_R0006 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D Metbo_R0001 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D Metbo_R0004 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D Metbo_R0005 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D Metbo_R0015 tRNA-Asn K14220 tRNA-Asn; tRNA Asn D Metbo_R0047 tRNA-Asp K14221 tRNA-Asp; tRNA Asp D Metbo_R0009 tRNA-Cys K14222 tRNA-Cys; tRNA Cys D Metbo_R0029 tRNA-Cys K14222 tRNA-Cys; tRNA Cys D Metbo_R0016 tRNA-Gln K14223 tRNA-Gln; tRNA Gln D Metbo_R0026 tRNA-Gln K14223 tRNA-Gln; tRNA Gln D Metbo_R0036 tRNA-Glu K14224 tRNA-Glu; tRNA Glu D Metbo_R0013 tRNA-Glu K14224 tRNA-Glu; tRNA Glu D Metbo_R0044 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D Metbo_R0043 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D Metbo_R0011 tRNA-His K14226 tRNA-His; tRNA His D Metbo_R0040 tRNA-Ile K14227 tRNA-Ile; tRNA Ile D Metbo_R0017 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D Metbo_R0012 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D Metbo_R0035 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D Metbo_R0041 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D Metbo_R0046 tRNA-Lys K14229 tRNA-Lys; tRNA Lys D Metbo_R0034 tRNA-Lys K14229 tRNA-Lys; tRNA Lys D Metbo_R0014 tRNA-Met K14230 tRNA-Met; tRNA Met D Metbo_R0007 tRNA-Met K14230 tRNA-Met; tRNA Met D Metbo_R0051 tRNA-Met K14230 tRNA-Met; tRNA Met D Metbo_R0037 tRNA-Phe K14231 tRNA-Phe; tRNA Phe D Metbo_R0049 tRNA-Pro K14232 tRNA-Pro; tRNA Pro D Metbo_R0045 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D Metbo_R0027 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D Metbo_R0025 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D Metbo_R0039 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D Metbo_R0018 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D Metbo_R0028 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D Metbo_R0050 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D Metbo_R0010 tRNA-Trp K14235 tRNA-Trp; tRNA Trp D Metbo_R0048 tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr D Metbo_R0003 tRNA-Val K14237 tRNA-Val; tRNA Val D Metbo_R0002 tRNA-Val K14237 tRNA-Val; tRNA Val D Metbo_R0038 tRNA-Val K14237 tRNA-Val; tRNA Val D Metbo_R0019 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D Metbo_R0033 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D Metbo_R0021 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D Metbo_R0031 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D Metbo_R0022 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D Metbo_R0023 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D Metbo_R0030 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D Metbo_R0024 ffs; SRP RNA; RNA component of signal recognition particle K01983 ffs; SRP RNA D Metbo_R0008 rnpB; RNA component of RNaseP K01978 rnpB; M1 RNA # A09190 Not Included in Pathway or Brite B B 09191 Unclassified: metabolism C 99980 Enzymes with EC numbers D Metbo_2341 oxidoreductase domain protein K18855 E1.1.1.374; UDP-N-acetylglucosamine 3-dehydrogenase [EC:1.1.1.374] D Metbo_0666 indolepyruvate ferredoxin oxidoreductase, alpha subunit K00179 iorA; indolepyruvate ferredoxin oxidoreductase, alpha subunit [EC:1.2.7.8] D Metbo_0667 indolepyruvate ferredoxin oxidoreductase, beta subunit K00180 iorB; indolepyruvate ferredoxin oxidoreductase, beta subunit [EC:1.2.7.8] D Metbo_0618 NADPH-dependent F420 reductase K06988 fno; 8-hydroxy-5-deazaflavin:NADPH oxidoreductase [EC:1.5.1.40] D Metbo_0137 flavodoxin/nitric oxide synthase K19817 fprA; coenzyme F420H2 oxidase [EC:1.5.3.22] D Metbo_0708 flavodoxin/nitric oxide synthase K19817 fprA; coenzyme F420H2 oxidase [EC:1.5.3.22] D Metbo_0139 CoA-disulfide reductase K17870 nox1; NADH oxidase (H2O2-forming) [EC:1.6.3.3] D Metbo_1416 Peptide methionine sulfoxide reductase msrA K07304 msrA; peptide-methionine (S)-S-oxide reductase [EC:1.8.4.11] D Metbo_2359 Peptide methionine sulfoxide reductase msrB K07305 msrB; peptide-methionine (R)-S-oxide reductase [EC:1.8.4.12] D Metbo_1621 Chloride peroxidase K00433 cpo; non-heme chloroperoxidase [EC:1.11.1.10] D Metbo_1449 Pirin domain protein K06911 PIR; quercetin 2,3-dioxygenase [EC:1.13.11.24] D Metbo_0935 desulfoferrodoxin K05919 dfx; superoxide reductase [EC:1.15.1.2] D Metbo_1001 Ferroxidase K02217 ftnA; ferritin [EC:1.16.3.2] D Metbo_1860 protein tyrosine phosphatase K03741 arsC; arsenate reductase (thioredoxin) [EC:1.20.4.4] D Metbo_1946 Radical SAM domain protein K06937 E1.21.98.5; tetraether lipid synthase [EC:1.21.98.5] D Metbo_0179 Radical SAM domain protein K04069 pflA; pyruvate formate lyase activating enzyme [EC:1.97.1.4] D Metbo_2296 anaerobic ribonucleoside-triphosphate reductase activating protein K04069 pflA; pyruvate formate lyase activating enzyme [EC:1.97.1.4] D Metbo_1942 Protein-L-isoaspartate O-methyltransferase K00573 E2.1.1.77; protein-L-isoaspartate(D-aspartate) O-methyltransferase [EC:2.1.1.77] D Metbo_0693 diphthine synthase K20215 dph5; diphthine synthase [EC:2.1.1.98] D Metbo_0348 methanogenesis marker protein 10 K25222 mmp10; [methyl coenzyme M reductase]-L-arginine C-5-methyltransferase [EC:2.1.1.379] D Metbo_0837 protein of unknown function DUF166 K22882 K22882; thymidylate synthase [EC:2.1.1.-] D Metbo_1401 GCN5-related N-acetyltransferase K03824 yhbS; putative acetyltransferase [EC:2.3.1.-] D Metbo_0721 glycosyl transferase group 1 K00754 bshA; L-malate glycosyltransferase [EC:2.4.1.-] D Metbo_0859 glycosyl transferase group 1 K00754 bshA; L-malate glycosyltransferase [EC:2.4.1.-] D Metbo_1976 deoxyhypusine synthase K00809 DHPS; deoxyhypusine synthase [EC:2.5.1.46] D Metbo_2420 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase K06898 larB; pyridinium-3,5-biscarboxylic acid mononucleotide synthase [EC:2.5.1.143] D Metbo_2039 PUA domain containing protein K07557 tgtA2; archaeosine synthase alpha-subunit [EC:2.6.1.97 2.6.1.-] D Metbo_0504 Conserved hypothetical protein CHP01210 K06936 raSEA; archaeosine synthase beta-subunit [EC:2.6.1.-] D Metbo_0521 phosphatidate cytidylyltransferase K18678 VTE5; phytol kinase [EC:2.7.1.182] D Metbo_0705 2-phosphoglycerate kinase K05715 2PGK; 2-phosphoglycerate kinase [EC:2.7.2.16] D Metbo_0586 CDP-alcohol phosphatidyltransferase K17884 E2.7.8.39; archaetidylinositol phosphate synthase [EC:2.7.8.39] D Metbo_2106 thioesterase superfamily protein K07107 ybgC; acyl-CoA thioester hydrolase [EC:3.1.2.-] D Metbo_0495 protein of unknown function DUF89 K09116 K09116; damage-control phosphatase, subfamily I [EC:3.1.3.-] D Metbo_2127 hydrolase, TatD family K03424 tatD; TatD DNase family protein [EC:3.1.21.-] D Metbo_1890 UPF0286 protein K07503 nucS; endonuclease [EC:3.1.-.-] D Metbo_1960 Glutamine--fructose-6-phosphate transaminase (isomerizing) K10708 frlB; fructoselysine 6-phosphate deglycase [EC:3.5.-.-] D Metbo_0254 YjeF-related protein K23997 nnr; ADP-dependent NAD(P)H-hydrate dehydratase / NAD(P)H-hydrate epimerase [EC:4.2.1.136 5.1.99.6] D Metbo_2234 Conserved hypothetical protein CHP00268 K06864 larE; pyridinium-3,5-biscarboxylic acid mononucleotide sulfurtransferase [EC:4.4.1.37] D Metbo_0391 UPF0272 protein K09121 larC; pyridinium-3,5-bisthiocarboxylic acid mononucleotide nickel chelatase [EC:4.99.1.12] D Metbo_0407 methanogenesis marker protein 1 K24409 ycaO; thioglycine synthase [EC:6.2.2.1] D Metbo_1369 Cyclic 2,3-diphosphoglycerate synthetase K05716 CPGS; cyclic 2,3-diphosphoglycerate synthase [EC:6.5.1.9] D Metbo_0299 Y414 protein K07468 K07468; DNA/RNA ligase [EC:6.5.1.-] D Metbo_1270 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein K03616 rnfB; H+/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit B [EC:7.1.1.11 7.2.1.2] D Metbo_1095 copper-translocating P-type ATPase K01533 copB; P-type Cu2+ transporter [EC:7.2.2.9] D Metbo_2224 calcium-translocating P-type ATPase, PMCA-type K01537 ATP2C; P-type Ca2+ transporter type 2C [EC:7.2.2.10] D Metbo_1239 heavy metal translocating P-type ATPase K01534 zntA; Zn2+/Cd2+-exporting ATPase [EC:7.2.2.12 7.2.2.21] C 99981 Carbohydrate metabolism D Metbo_0036 Sugar fermentation stimulation protein A K06206 sfsA; sugar fermentation stimulation protein A D Metbo_0978 Lactate utilization protein B/C K00782 lldG; L-lactate dehydrogenase complex protein LldG C 99982 Energy metabolism D Metbo_0138 Rubrerythrin K19824 fprB; rubrerythrin D Metbo_2521 Protein fdhD K02379 fdhD; FdhD protein D Metbo_1882 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein K05337 fer; ferredoxin D Metbo_1231 FeS cluster assembly scaffold protein NifU K04488 iscU; nitrogen fixation protein NifU and related proteins D Metbo_0690 Radical SAM domain protein K02585 nifB; nitrogen fixation protein NifB D Metbo_2413 nitrogenase MoFe cofactor biosynthesis protein NifE K02587 nifE; nitrogenase molybdenum-cofactor synthesis protein NifE D Metbo_1290 hypothetical protein K14092 ehaA; energy-converting hydrogenase A subunit A D Metbo_1289 energy-converting hydrogenase A, subunit B K14093 ehaB; energy-converting hydrogenase A subunit B D Metbo_1288 Protein of unknown function DUF2109, membrane K14094 ehaC; energy-converting hydrogenase A subunit C D Metbo_1287 Protein of unknown function DUF2108, membrane K14095 ehaD; energy-converting hydrogenase A subunit D D Metbo_1286 (NiFe)-hydrogenase-3-type complex Eha, membrane protein EhaE K14096 ehaE; energy-converting hydrogenase A subunit E D Metbo_1285 (NiFe)-hydrogenase-3-type complex Eha, membrane protein EhaF K14097 ehaF; energy-converting hydrogenase A subunit F D Metbo_1284 Protein of unknown function DUF2105, membrane K14098 ehaG; energy-converting hydrogenase A subunit G D Metbo_1283 (NiFe)-hydrogenase-3-type complex Eha, membrane protein EhaH K14099 ehaH; energy-converting hydrogenase A subunit H D Metbo_1282 energy-converting hydrogenase A subunit I EhaI K14100 ehaI; energy-converting hydrogenase A subunit I D Metbo_1281 respiratory-chain NADH dehydrogenase subunit 1 K14101 ehaJ; energy-converting hydrogenase A subunit J D Metbo_1280 energy-converting hydrogenase A, subunit K K14102 ehaK; energy-converting hydrogenase A subunit K D Metbo_1279 Protein of unknown function DUF2104, membrane K14103 ehaL; energy-converting hydrogenase A subunit L D Metbo_1278 (NiFe)-hydrogenase-3-type complex Eha, EhaM K14104 ehaM; energy-converting hydrogenase A subunit M D Metbo_1277 NADH ubiquinone oxidoreductase 20 kDa subunit K14105 ehaN; energy-converting hydrogenase A subunit N D Metbo_1276 NADH dehydrogenase (quinone) K14106 ehaO; energy-converting hydrogenase A subunit O D Metbo_1275 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein K14107 ehaP; energy-converting hydrogenase A subunit P D Metbo_1274 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein K14108 ehaQ; energy-converting hydrogenase A subunit Q D Metbo_1273 hypothetical protein K14109 ehaR; energy-converting hydrogenase A subunit R D Metbo_0259 cation antiporter K14110 ehbA; energy-converting hydrogenase B subunit A D Metbo_0260 multiple resistance and pH regulation protein F K14111 ehbB; energy-converting hydrogenase B subunit B D Metbo_0261 energy-converting hydrogenase B, subunit C K14112 ehbC; energy-converting hydrogenase B subunit C D Metbo_0262 energy-converting hydrogenase B, subunit D K14113 ehbD; energy-converting hydrogenase B subunit D D Metbo_0263 NADH-ubiquinone oxidoreductase chain 4L K14114 ehbE; energy-converting hydrogenase B subunit E D Metbo_0265 NADH dehydrogenase (quinone) K14115 ehbF; energy-converting hydrogenase B subunit F D Metbo_0266 hypothetical protein K14116 ehbG; energy-converting hydrogenase B subunit G D Metbo_0267 energy-converting hydrogenase B, subunit H K14117 ehbH; energy-converting hydrogenase B subunit H D Metbo_0268 Na+/H+ antiporter MnhB subunit-related protein K14118 ehbI; energy-converting hydrogenase B subunit I D Metbo_0269 energy-converting hydrogenase B, subunit J K14119 ehbJ; energy-converting hydrogenase B subunit J D Metbo_0270 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein K14120 ehbK; energy-converting hydrogenase B subunit K D Metbo_0271 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein K14121 ehbL; energy-converting hydrogenase B subunit L D Metbo_0272 NADH ubiquinone oxidoreductase 20 kDa subunit K14122 ehbM; energy-converting hydrogenase B subunit M D Metbo_0273 NADH dehydrogenase (quinone) K14123 ehbN; energy-converting hydrogenase B subunit N D Metbo_0274 NADH dehydrogenase (ubiquinone), subunit 1 related protein K14124 ehbO; energy-converting hydrogenase B subunit O D Metbo_0275 Energy-converting hydrogenase B, subunit P K14125 ehbP; energy-converting hydrogenase B subunit P D Metbo_0281 amino acid-binding ACT domain protein K06862 ehbQ; energy-converting hydrogenase B subunit Q D Metbo_2144 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein K02574 napH; ferredoxin-type protein NapH C 99983 Lipid metabolism C 99984 Nucleotide metabolism C 99985 Amino acid metabolism C 99986 Glycan metabolism D Metbo_0251 Lysylphosphatidylglycerol synthetase/UPF0104 K07027 K07027; glycosyltransferase 2 family protein D Metbo_2334 Lysylphosphatidylglycerol synthetase/UPF0104 K07027 K07027; glycosyltransferase 2 family protein C 99987 Cofactor metabolism D Metbo_0591 ABC-1 domain-containing protein K03688 ubiB; ubiquinone biosynthesis protein D Metbo_2516 molybdopterin-guanine dinucleotide biosynthesis protein B K03753 mobB; molybdopterin-guanine dinucleotide biosynthesis adapter protein C 99988 Secondary metabolism C 99999 Others D Metbo_2235 TfuA-like core domain-containing protein K24410 tfuA; TfuA protein B B 09192 Unclassified: genetic information processing C 99973 Transcription D Metbo_2221 transcriptional regulator, XRE family K03627 MBF1; putative transcription factor D Metbo_0063 DNA/RNA-binding protein Alba K03622 ssh10b; archaea-specific DNA-binding protein D Metbo_1991 DNA/RNA-binding protein Alba K03622 ssh10b; archaea-specific DNA-binding protein D Metbo_2101 snRNP Sm-like protein K04796 RUXX; small nuclear ribonucleoprotein D Metbo_2417 nitrogen regulatory protein P-II K02589 nifHD1; nitrogen regulatory protein PII 1 D Metbo_2416 nitrogen regulatory protein P-II K02590 nifHD2; nitrogen regulatory protein PII 2 D Metbo_1977 putative signal transduction protein with CBS domains K07744 K07744; transcriptional regulator C 99974 Translation D Metbo_0192 protein of unknown function DUF655 K07572 K07572; putative nucleotide binding protein D Metbo_0765 Methyltransferase type 11 K07579 K07579; putative methylase D Metbo_0404 Zn-ribbon RNA-binding protein K07580 K07580; Zn-ribbon RNA-binding protein D Metbo_2191 protein of unknown function DUF54 K07581 K07581; RNA-binding protein D Metbo_0542 Queuosine synthesis-like protein K07585 K07585; tRNA methyltransferase C 99975 Protein processing D Metbo_2050 hydrogenase assembly chaperone hypC/hupF K04653 hypC; hydrogenase expression/formation protein HypC D Metbo_2263 hydrogenase expression/formation protein HypD K04654 hypD; hydrogenase expression/formation protein HypD D Metbo_2168 hydrogenase expression/formation protein HypE K04655 hypE; hydrogenase expression/formation protein HypE D Metbo_0232 Acylphosphatase K04656 hypF; hydrogenase maturation protein HypF D Metbo_0040 AIR synthase related protein domain protein K07388 K07388; hydrogenase expression/formation protein D Metbo_2465 glutaredoxin K06191 nrdH; glutaredoxin-like protein NrdH D Metbo_2444 AAA ATPase central domain protein K07392 PRS2; AAA family ATPase C 99976 Replication and repair D Metbo_1085 HhH-GPD family protein K07457 K07457; endonuclease III related protein D Metbo_2157 phage/plasmid primase, P4 family K06919 K06919; putative DNA primase/helicase C 99979 Viral proteins C 99998 Others B B 09193 Unclassified: signaling and cellular processes C 99977 Transport D Metbo_1867 amino acid permease-associated region K03294 TC.APA; basic amino acid/polyamine antiporter, APA family D Metbo_1868 amino acid permease-associated region K03294 TC.APA; basic amino acid/polyamine antiporter, APA family D Metbo_1242 amino acid permease-associated region K03294 TC.APA; basic amino acid/polyamine antiporter, APA family D Metbo_2031 amino acid/peptide transporter K03305 TC.POT; proton-dependent oligopeptide transporter, POT family D Metbo_0709 phosphate transporter K03306 TC.PIT; inorganic phosphate transporter, PiT family D Metbo_0670 SSS sodium solute transporter superfamily K03307 TC.SSS; solute:Na+ symporter, SSS family D Metbo_0676 SSS sodium solute transporter superfamily K03307 TC.SSS; solute:Na+ symporter, SSS family D Metbo_1524 Bile acid:sodium symporter K03453 TC.BASS; bile acid:Na+ symporter, BASS family C 99978 Cell growth D Metbo_0378 Cobyrinic acid ac-diamide synthase K07321 cooC; CO dehydrogenase maturation factor D Metbo_0465 Cobyrinic acid ac-diamide synthase K07321 cooC; CO dehydrogenase maturation factor D Metbo_0255 sigmaK-factor processing regulatory BofA K06317 bofA; inhibitor of the pro-sigma K processing machinery D Metbo_0614 protein of unknown function DUF95 transmembrane K06384 spoIIM; stage II sporulation protein M D Metbo_1721 protein of unknown function DUF95 transmembrane K06384 spoIIM; stage II sporulation protein M C 99993 Cell motility C 99995 Signaling proteins D Metbo_0541 DNA-binding protein K06875 PDCD5; programmed cell death protein 5 C 99992 Structural proteins D Metbo_1438 Tetratricopeptide TPR_1 repeat-containing protein K05803 nlpI; lipoprotein NlpI D Metbo_1090 protein of unknown function UPF0118 K11744 tqsA; AI-2 transport protein TqsA D Metbo_0768 hypothetical protein K21908 hdeD; membrane protein HdeD D Metbo_0673 hypothetical protein K21908 hdeD; membrane protein HdeD C 99994 Others D Metbo_0475 phosphate uptake regulator, PhoU K02039 phoU; phosphate transport system protein D Metbo_0481 phosphate uptake regulator, PhoU K02039 phoU; phosphate transport system protein D Metbo_0483 phosphate uptake regulator, PhoU K02039 phoU; phosphate transport system protein D Metbo_0018 CutA1 divalent ion tolerance protein K03926 cutA; periplasmic divalent cation tolerance protein D Metbo_1439 parallel beta-helix repeat K07218 nosD; nitrous oxidase accessory protein B B 09194 Poorly characterized C 99996 General function prediction only D Metbo_0620 PilT protein domain protein K06865 K06865; ATPase D Metbo_2172 HAD superfamily (subfamily IA) hydrolase, TIGR02253 K07025 K07025; putative hydrolase of the HAD superfamily D Metbo_0366 SufBD protein K09014 sufB; Fe-S cluster assembly protein SufB D Metbo_0258 Protein of unknown function DUF457, transmembrane K07038 K07038; inner membrane protein D Metbo_1120 Protein of unknown function DUF457, transmembrane K07038 K07038; inner membrane protein D Metbo_1697 Protein of unknown function DUF457, transmembrane K07038 K07038; inner membrane protein D Metbo_0868 Protein of unknown function DUF457, transmembrane K07038 K07038; inner membrane protein D Metbo_0625 TatD-related deoxyribonuclease K07049 K07049; TatD-related deoxyribonuclease D Metbo_1812 LemA family protein K03744 lemA; LemA protein D Metbo_1471 LemA family protein K03744 lemA; LemA protein D Metbo_1711 YhgE/Pip N-terminal domain protein K01421 yhgE; putative membrane protein D Metbo_0458 protein of unknown function DUF112 transmembrane K08971 K08971; putative membrane protein D Metbo_0742 Protein of unknown function DUF2070, membrane K08979 K08979; putative membrane protein C 99997 Function unknown D Metbo_0216 Conserved hypothetical protein CHP00061 K06869 K06869; uncharacterized protein D Metbo_2024 Radical SAM domain protein K06871 K06871; uncharacterized protein D Metbo_0990 metal dependent phosphohydrolase K06885 K06885; uncharacterized protein D Metbo_1019 hypothetical protein K06888 K06888; uncharacterized protein D Metbo_1989 hypothetical protein K06893 K06893; uncharacterized protein D Metbo_0444 ATP-grasp fold domain protein, DUF201-type K06913 K06913; uncharacterized protein D Metbo_0505 protein of unknown function DUF815 K06923 K06923; uncharacterized protein D Metbo_0509 UPF0251 protein K06933 K06933; uncharacterized protein D Metbo_1247 DNA-binding protein K06933 K06933; uncharacterized protein D Metbo_0290 protein of unknown function DUF296 K06934 K06934; uncharacterized protein D Metbo_2241 Fe-S cluster domain protein K06939 K06939; uncharacterized protein D Metbo_0449 protein of unknown function UPF0153 K06940 K06940; uncharacterized protein D Metbo_1336 small GTP-binding protein K06945 K06945; uncharacterized protein D Metbo_0941 small GTP-binding protein K06945 K06945; uncharacterized protein D Metbo_2238 metal dependent phosphohydrolase K06950 K06950; uncharacterized protein D Metbo_1874 phosphoesterase K06953 K06953; uncharacterized protein D Metbo_1809 APHP domain protein K06987 K06987; uncharacterized protein D Metbo_1604 Succinylglutamate desuccinylase/aspartoacylase K06987 K06987; uncharacterized protein D Metbo_1793 peptidase C39 bacteriocin processing K06992 K06992; uncharacterized protein D Metbo_1719 Glyoxalase/bleomycin resistance protein/dioxygenase K06996 K06996; uncharacterized protein D Metbo_1706 pyridoxamine 5'-phosphate oxidase-related FMN-binding protein K07005 K07005; uncharacterized protein D Metbo_1814 pyridoxamine 5'-phosphate oxidase-related FMN-binding protein K07005 K07005; uncharacterized protein D Metbo_1373 pyridoxamine 5'-phosphate oxidase-related FMN-binding protein K07005 K07005; uncharacterized protein D Metbo_1211 pyridoxamine 5'-phosphate oxidase-related FMN-binding protein K07006 K07006; uncharacterized protein D Metbo_1678 pyridoxamine 5'-phosphate oxidase-related FMN-binding protein K07006 K07006; uncharacterized protein D Metbo_0136 transcriptional regulator, ArsR family K07013 K07013; uncharacterized protein D Metbo_0993 transcriptional regulator, ArsR family K07013 K07013; uncharacterized protein D Metbo_0393 4-vinyl reductase 4VR K07013 K07013; uncharacterized protein D Metbo_2138 transcriptional regulator, ArsR family K07013 K07013; uncharacterized protein D Metbo_1020 transcriptional regulator, ArsR family K07013 K07013; uncharacterized protein D Metbo_1897 GPR1/FUN34/yaaH family protein K07034 K07034; uncharacterized protein D Metbo_0322 KH-domain/beta-lactamase-domain protein K07041 K07041; uncharacterized protein D Metbo_0659 TatD-related deoxyribonuclease K07051 K07051; uncharacterized protein D Metbo_0182 protein of unknown function DUF35 K07068 K07068; uncharacterized protein D Metbo_0317 NADP-dependent oxidoreductase domain protein K07079 K07079; uncharacterized protein D Metbo_1730 NADP-dependent oxidoreductase domain protein K07079 K07079; uncharacterized protein D Metbo_1529 NADP-dependent oxidoreductase domain protein K07079 K07079; uncharacterized protein D Metbo_1716 NADP-dependent oxidoreductase domain protein K07079 K07079; uncharacterized protein D Metbo_2058 protein of unknown function DUF81 K07090 K07090; uncharacterized protein D Metbo_1410 protein of unknown function DUF81 K07090 K07090; uncharacterized protein D Metbo_1448 protein of unknown function DUF81 K07090 K07090; uncharacterized protein D Metbo_0513 protein of unknown function DUF81 K07090 K07090; uncharacterized protein D Metbo_1442 DsrE family protein K07092 K07092; uncharacterized protein D Metbo_0250 phosphodiesterase, MJ0936 family K07095 K07095; uncharacterized protein D Metbo_0532 phosphodiesterase, MJ0936 family K07095 K07095; uncharacterized protein D Metbo_0704 metallophosphoesterase K07096 K07096; uncharacterized protein D Metbo_0158 metallophosphoesterase K07098 K07098; uncharacterized protein D Metbo_0347 metallophosphoesterase K07098 K07098; uncharacterized protein D Metbo_2049 regulatory protein K07103 K07103; uncharacterized protein D Metbo_0651 3H domain-containing protein K07105 K07105; uncharacterized protein D Metbo_1177 hypothetical protein K07108 K07108; uncharacterized protein D Metbo_0683 methanogenesis marker protein 2 K07123 K07123; uncharacterized protein D Metbo_0394 Roadblock/LC7 family protein K07131 K07131; uncharacterized protein D Metbo_0652 Roadblock/LC7 family protein K07131 K07131; uncharacterized protein D Metbo_1335 Roadblock/LC7 family protein K07131 K07131; uncharacterized protein D Metbo_0595 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase K07134 K07134; uncharacterized protein D Metbo_0416 t-RNA-binding domain-containing protein K07135 K07135; uncharacterized protein D Metbo_0035 FAD-dependent pyridine nucleotide-disulfide oxidoreductase K07137 K07137; uncharacterized protein D Metbo_0057 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein K07138 K07138; uncharacterized protein D Metbo_0604 protein of unknown function DUF652 K07158 K07158; uncharacterized protein D Metbo_0211 Conserved hypothetical protein CHP00062 K07159 K07159; uncharacterized protein D Metbo_1885 VWA containing CoxE family protein K07161 K07161; uncharacterized protein D Metbo_0739 Protein of unknown function DUF2072, Zinc-ribbon K07163 K07163; uncharacterized protein D Metbo_0552 protein of unknown function DUF763 K09003 K09003; uncharacterized protein D Metbo_0156 protein of unknown function DUF192 K09005 K09005; uncharacterized protein D Metbo_0201 UPF0215 protein K09120 K09120; uncharacterized protein D Metbo_2246 hypothetical protein K09126 K09126; uncharacterized protein D Metbo_2457 protein of unknown function DUF355 K09129 K09129; uncharacterized protein D Metbo_2086 UPF0235 protein yggU K09131 K09131; uncharacterized protein D Metbo_0291 protein of unknown function DUF366 K09139 K09139; uncharacterized protein D Metbo_1963 AMMECR1-domain protein K09141 K09141; uncharacterized protein D Metbo_1928 hypothetical protein K09143 K09143; uncharacterized protein D Metbo_1951 protein of unknown function DUF460 K09150 K09150; uncharacterized protein D Metbo_2352 protein of unknown function DUF447 K09154 K09154; uncharacterized protein D Metbo_2325 protein of unknown function DUF1284 K09706 K09706; uncharacterized protein D Metbo_2225 protein of unknown function UPF0146 K09713 K09713; uncharacterized protein D Metbo_0289 DNA polymerase beta domain protein region K09717 K09717; uncharacterized protein D Metbo_0113 UPF0147 protein K09721 K09721; uncharacterized protein D Metbo_1343 protein of unknown function DUF530 K09724 K09724; uncharacterized protein D Metbo_2220 protein of unknown function DUF356 K09727 K09727; uncharacterized protein D Metbo_0585 Domain of unknown function DUF357 K09728 K09728; uncharacterized protein D Metbo_2276 protein of unknown function DUF116 K09729 K09729; uncharacterized protein D Metbo_1017 UPF0179 protein K09730 K09730; uncharacterized protein D Metbo_2332 protein of unknown function DUF211 K09732 K09732; uncharacterized protein D Metbo_1162 protein of unknown function DUF54 K09736 K09736; uncharacterized protein D Metbo_0442 protein of unknown function DUF61 K09737 K09737; uncharacterized protein D Metbo_2090 protein of unknown function DUF371 K09738 K09738; uncharacterized protein D Metbo_2369 UPF0280 protein K09740 K09740; uncharacterized protein D Metbo_0738 Uncharacterized conserved protein UCP004977 K09743 K09743; uncharacterized protein D Metbo_1420 hypothetical protein K07502 yprB; uncharacterized protein D Metbo_0584 protein of unknown function DUF47 K07220 K07220; uncharacterized protein ! #
#[ KO | BRITE | KEGG2 | KEGG ]
#Last updated: June 15, 2024