+C Two-component system KO
#
Two-Component System - Corallococcus macrosporus HW-1
%
!
AOmpR family
B PhoR-PhoB (phosphate starvation response)
C LILAB_31840 sensory box histidine kinase PhoR1 K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]
C LILAB_02050 sensor histidine kinase K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]
C LILAB_16335 sensor histidine kinase K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]
C LILAB_31875 phosphate regulon transcriptional regulatory protein PhoB K07657 phoB; two-component system, OmpR family, phosphate regulon response regulator PhoB
C LILAB_31835 DNA-binding response regulator PhoP1 K07657 phoB; two-component system, OmpR family, phosphate regulon response regulator PhoB
B SenX3-RegX3 (phosphate starvation response)
C LILAB_14485 sensor histidine kinase PhoR3 K07768 senX3; two-component system, OmpR family, sensor histidine kinase SenX3 [EC:2.7.13.3]
B PhoQ-PhoP (magnesium transport)
B EnvZ-OmpR (osmotic stress response)
B RstB-RstA
B CpxA-CpxR (envelope stress response)
B CssS-CssR (secretion stress response)
B CreC-CreB (phosphate regulation)
C LILAB_28980 sensor histidine kinase K07641 creC; two-component system, OmpR family, sensor histidine kinase CreC [EC:2.7.13.3]
B BaeS-BaeR (envelope stress response)
B BasS-BasR (antimicrobial peptide resistance)
B CusS-CusR (copper tolerance)
C LILAB_35995 sensor histidine kinase K07644 cusS; two-component system, OmpR family, heavy metal sensor histidine kinase CusS [EC:2.7.13.3]
B QseC-QseB (quorum sensing)
B KdpD-KdpE (potassium transport)
B TorS-TorR (TMAO respiration)
B ArcB-ArcA (anoxic redox control)
B TctE-TctD (tricarboxylic acid transport)
B ResE-ResD (aerobic and anaerobic respiration)
B VicK-VicR (cell wall metabolism)
C LILAB_07860 sensory box histidine kinase K07652 vicK; two-component system, OmpR family, sensor histidine kinase VicK [EC:2.7.13.3]
C LILAB_05590 sensory box histidine kinase K07652 vicK; two-component system, OmpR family, sensor histidine kinase VicK [EC:2.7.13.3]
C LILAB_35015 response regulator K07668 vicR; two-component system, OmpR family, response regulator VicR
B MprB-MprA (maintenance of persistent infection)
B MtrB-MtrA (osmotic stress response)
C LILAB_10475 sensor histidine kinase K07654 mtrB; two-component system, OmpR family, sensor histidine kinase MtrB [EC:2.7.13.3]
C LILAB_16020 sensor histidine kinase K07654 mtrB; two-component system, OmpR family, sensor histidine kinase MtrB [EC:2.7.13.3]
B PrrB-PrrA (intracellular multiplication)
B TrcS-TrcR
B NrsS-NrsR (nickel tolerance)
B ManS-ManR (manganese homeostasis)
B NblS-NblR (photosynthesis)
B SasA-RpaAB (circadian timing mediating)
B SaeS-SaeR (staphylococcal virulence regulation)
B BceS-BceR (bacitracin transport)
B BraS-BraR (bacitracin transport)
B GraS-GraR (cationic antimicrobial peptide transport)
B YxdK-YxdJ (antimicrobial peptide response)
B ChvG-ChvI (acidity sensing)
B CiaH-CiaR
B ParS-ParR (polymyxin-adaptive resistance)
B AdeS-AdeR
B VanS-VanR (VanB type vancomycin resistance)
B VanS-VanR (VanE type vancomycin resistance)
B VanS-VanR (actinomycete type vancomycin resistance)
B ArlS-ArlR (virulence regulation)
B Ihk-Irr (virulence regulation)
B PfeS-PfeR (enterobactin-dependent iron acquisition)
B NisK-NisR (lantibiotic biosynthesis)
B Unclassified
C LILAB_11765 sensor histidine kinase K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
C LILAB_07755 sensor histidine kinase K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
C LILAB_02770 sensor histidine kinase K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
C LILAB_22535 sensor histidine kinase K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
C LILAB_21130 sensor histidine kinase K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
C LILAB_34405 sensor histidine kinase K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
C LILAB_28975 DNA-binding response regulator K02483 K02483; two-component system, OmpR family, response regulator
C LILAB_05130 response regulator K02483 K02483; two-component system, OmpR family, response regulator
C LILAB_05155 response regulator K02483 K02483; two-component system, OmpR family, response regulator
C LILAB_13380 response regulator K02483 K02483; two-component system, OmpR family, response regulator
C LILAB_16310 DNA-binding response regulator K02483 K02483; two-component system, OmpR family, response regulator
C LILAB_14490 DNA-binding response regulator PhoP3 K02483 K02483; two-component system, OmpR family, response regulator
C LILAB_25010 DNA-binding heavy metal response regulator K02483 K02483; two-component system, OmpR family, response regulator
C LILAB_21595 DNA-binding response regulator PhoP2 K02483 K02483; two-component system, OmpR family, response regulator
C LILAB_34400 DNA-binding response regulator K02483 K02483; two-component system, OmpR family, response regulator
#
ANarL family
B NarX-NarL (nitrate respiration)
C LILAB_05150 response regulator K07684 narL; two-component system, NarL family, nitrate/nitrite response regulator NarL
B NarQ-NarP (nitrate respiration)
B UhpB-UhpA (hexose phosphates uptake)
B FusK-FusR (virulence regulation)
B RcsC-RcsD-RcsB (capsule synthesis)
B BarA-UvrY (central carbon metabolism)
B ComP-ComA (competence)
B EvgS-EvgA (acid and drug tolerance)
B DegS-DegU (multicellular behavior control)
C LILAB_28525 sensor histidine kinase K07777 degS; two-component system, NarL family, sensor histidine kinase DegS [EC:2.7.13.3]
B DesK-DesR (membrane lipid fluidity regulation)
B VraS-VraR (cell-wall peptidoglycan synthesis)
B LiaS-LiaR (cell wall stress response)
B DevS-DevR (redox response)
B NreB-NreC (dissimilatory nitrate/nitrite reduction)
B YdfH-YdfI
B SalK-SalR
B PprA–PprB (biofilm formation)
B Unclassified
#
ASpo family
B KinABCDE-Spo0FA (sporulation control)
C LILAB_01905 response regulator K02490 spo0F; two-component system, response regulator, stage 0 sporulation protein F
#
ACitB family
B CitA-CitB (citrate fermentation)
B CitS-CitT (magnesium-citrate transport)
B DcuS-DcuR (C4-dicarboxylate metabolism)
B DctS-DctR (C4-dicarboxylate transport)
B MalK-MalR (malate transport)
B Unclassified
#
ALytTR family
B LysS-LysR
B AlgZ-AlgR (alginate production)
C LILAB_02325 histidine kinase family protein K08082 algZ; two-component system, LytTR family, sensor histidine kinase AlgZ [EC:2.7.13.3]
C LILAB_06795 Sensor protein lytS K08082 algZ; two-component system, LytTR family, sensor histidine kinase AlgZ [EC:2.7.13.3]
B NatK-NatR (sodium extrusion)
B AgrC-AgrA (exoprotein synthesis)
B AgrC2-AgrA2 (virulence regulation)
B ComD-ComE (competence)
B Unclassified
C LILAB_02330 response regulator K02477 K02477; two-component system, LytTR family, response regulator
C LILAB_06800 two component transcriptional regulator, LytTR family protein K02477 K02477; two-component system, LytTR family, response regulator
#
ANtrC family
B GlnL-GlnG (nitrogen regulation)
C LILAB_04410 Fis family sigma-54 dependent transcriptional regulator K07712 glnG; two-component system, NtrC family, nitrogen regulation response regulator GlnG
C LILAB_26630 sigma-54 dependent transcription regulator K07712 glnG; two-component system, NtrC family, nitrogen regulation response regulator GlnG
B NtrY-NtrX (nitrogen regulation)
C LILAB_02645 sensor histidine kinase K13598 ntrY; two-component system, NtrC family, nitrogen regulation sensor histidine kinase NtrY [EC:2.7.13.3]
C LILAB_02650 sigma-54 dependent DNA-binding response regulator K13599 ntrX; two-component system, NtrC family, nitrogen regulation response regulator NtrX
B HydH-HydG (metal tolerance)
C LILAB_29115 sensor histidine kinase K07709 zraS; two-component system, NtrC family, sensor histidine kinase HydH [EC:2.7.13.3]
C LILAB_03250 sensory box histidine kinase K07709 zraS; two-component system, NtrC family, sensor histidine kinase HydH [EC:2.7.13.3]
C LILAB_02970 sensor histidine kinase FrgB K07709 zraS; two-component system, NtrC family, sensor histidine kinase HydH [EC:2.7.13.3]
C LILAB_06400 sensor histidine kinase K07709 zraS; two-component system, NtrC family, sensor histidine kinase HydH [EC:2.7.13.3]
C LILAB_16225 sensor histidine kinase K07709 zraS; two-component system, NtrC family, sensor histidine kinase HydH [EC:2.7.13.3]
C LILAB_24490 sensor histidine kinase K07709 zraS; two-component system, NtrC family, sensor histidine kinase HydH [EC:2.7.13.3]
C LILAB_29355 sensor histidine kinase/response regulator K07709 zraS; two-component system, NtrC family, sensor histidine kinase HydH [EC:2.7.13.3]
C LILAB_29365 sensor histidine kinase K07709 zraS; two-component system, NtrC family, sensor histidine kinase HydH [EC:2.7.13.3]
C LILAB_33585 sensor histidine kinase MrpA K07709 zraS; two-component system, NtrC family, sensor histidine kinase HydH [EC:2.7.13.3]
C LILAB_29470 sensor histidine kinase K07709 zraS; two-component system, NtrC family, sensor histidine kinase HydH [EC:2.7.13.3]
C LILAB_02505 sigma-54 dependent DNA-binding response regulator SasR K07713 zraR; two-component system, NtrC family, response regulator HydG
C LILAB_03245 sigma-54 dependent DNA-binding response regulator Nla19 K07713 zraR; two-component system, NtrC family, response regulator HydG
C LILAB_30920 sigma-54 dependent DNA-binding response regulator K07713 zraR; two-component system, NtrC family, response regulator HydG
C LILAB_29465 sigma-54 dependent DNA-binding response regulator K07713 zraR; two-component system, NtrC family, response regulator HydG
C LILAB_20255 sigma-54 dependent DNA-binding response regulator K07713 zraR; two-component system, NtrC family, response regulator HydG
C LILAB_16895 sigma-54 dependent transcription regulator K07713 zraR; two-component system, NtrC family, response regulator HydG
C LILAB_28325 sigma-54 dependent DNA-binding response regulator Nla6 K07713 zraR; two-component system, NtrC family, response regulator HydG
B AtoS-AtoC (cPHB biosynthesis)
C LILAB_36375 sigma-54 dependent DNA-binding response regulator K07714 atoC; two-component system, NtrC family, response regulator AtoC
C LILAB_33590 sigma-54 dependent DNA-binding response regulator MrpB K07714 atoC; two-component system, NtrC family, response regulator AtoC
C LILAB_02975 sigma-54 dependent DNA-binding response regulator FrgC K07714 atoC; two-component system, NtrC family, response regulator AtoC
C LILAB_02765 sigma-54 dependent DNA-binding response regulator Nla28 K07714 atoC; two-component system, NtrC family, response regulator AtoC
C LILAB_04175 sigma-54 dependent transcription regulator K07714 atoC; two-component system, NtrC family, response regulator AtoC
C LILAB_23850 sigma-54 activator protein ActB K07714 atoC; two-component system, NtrC family, response regulator AtoC
C LILAB_29110 sigma-54 dependent DNA-binding response regulator K07714 atoC; two-component system, NtrC family, response regulator AtoC
C LILAB_25760 sigma-54 dependent DNA-binding response regulator K07714 atoC; two-component system, NtrC family, response regulator AtoC
C LILAB_04015 sigma-54 dependent DNA-binding response regulator K07714 atoC; two-component system, NtrC family, response regulator AtoC
B PilS-PilR (type 4 fimbriae synthesis)
C LILAB_36415 pilin regulatory protein PilS K02668 pilS; two-component system, NtrC family, sensor histidine kinase PilS [EC:2.7.13.3]
C LILAB_36410 pilin regulatory protein PilR K02667 pilR; two-component system, NtrC family, response regulator PilR
B GlrK-GlrR (amino sugar metabolism)
C LILAB_30890 RNA polymerase sigma factor 54 K07715 glrR; two-component system, NtrC family, response regulator GlrR
C LILAB_23195 sigma-54 dependent transcription regulator K07715 glrR; two-component system, NtrC family, response regulator GlrR
C LILAB_29825 sigma-54 dependent transcription regulator K07715 glrR; two-component system, NtrC family, response regulator GlrR
B PgtB-PgtA (phosphoglycerate transport)
B DctB-DctD (C4-dicarboxylate transport)
B KinB-AlgB (alginate production)
C LILAB_06940 sensory box histidine kinase K11383 kinB; two-component system, NtrC family, sensor histidine kinase KinB [EC:2.7.13.3]
B HupT-HupR (hydrogenase synthesis regulation)
B Unclassified
C LILAB_07085 sensory box histidine kinase/response regulator K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C LILAB_04010 sensor histidine kinase K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C LILAB_04060 sensor histidine kinase K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C LILAB_05675 sensor protein K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C LILAB_05770 sensory box histidine kinase K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C LILAB_21570 sensor histidine kinase/response regulator K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C LILAB_27975 sensory box sensor histidine kinase K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C LILAB_30355 sensor histidine kinase K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C LILAB_36380 sensor histidine kinase K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C LILAB_33055 sensor histidine kinase K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C LILAB_34655 response regulator/sensor histidine kinase HsfB K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C LILAB_21050 A-signal transduction regulator AsgA K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
#
ACheA family
B CheA-CheYBV (chemotaxis)
C LILAB_13000 histidine kinase DifE K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
C LILAB_11585 putative chemotaxis protein CheA K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
C LILAB_31740 CheW-like protein K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
C LILAB_28370 CheA signal transduction histidine kinase K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
C LILAB_21125 sensor histidine kinase/response regulator CheA4 K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
C LILAB_16155 chemotaxis sensor histidine kinase/response regulator K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
C LILAB_11650 sensor histidine kinase/response regulator K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
C LILAB_28855 gliding motility regulatory protein K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
C LILAB_33705 sensor histidine kinase/response regulator CheA3 K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
C LILAB_12995 fibril biogenesis regulator DifD K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C LILAB_11580 putative chemotaxis protein CheY K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C LILAB_16240 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C LILAB_16135 putative chemotaxis protein CheY K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C LILAB_31705 chemotaxis protein CheY K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C LILAB_31745 chemotaxis protein CheY K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C LILAB_11565 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C LILAB_07355 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C LILAB_16060 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C LILAB_30475 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C LILAB_05210 protein-glutamate methylesterase domain-containing protein K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
C LILAB_11610 protein-glutamate methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
C LILAB_16160 putative protein-glutamate methylesterase CheB K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
C LILAB_28850 protein-glutatmate methylesterase FrzG K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
C LILAB_31710 protein-glutamate methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
C LILAB_33685 protein-glutamate methylesterase CheB3 K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
B ChpA-ChpB/PilGH (chemosensory)
C LILAB_21115 response regulator CheY4 K02657 pilG; twitching motility two-component system response regulator PilG
B PixL-PixGH (positive phototaxis)
B WspE-WspRF (chemosensory)
B Cph1-Rcp1 (light response)
C LILAB_03710 sensor protein K11354 cph1; two-component system, chemotaxis family, sensor kinase Cph1 [EC:2.7.13.3]
C LILAB_03705 response regulator K11355 rcp1; two-component system, chemotaxis family, response regulator Rcp1
#
ACell cycle family
B PleC-PleD (cell fate control)
C LILAB_00995 response regulator K11443 divK; two-component system, cell cycle response regulator DivK
B CckA-CtrA/CpdR (cell cycle control)
C LILAB_14795 sensor histidine kinase/response regulator K13587 cckA; two-component system, cell cycle sensor histidine kinase and response regulator CckA [EC:2.7.13.3]
B Hk1-Rrp1 (glycerol uptake and utilization)
#
ALux family
B LuxQN/CqsS-LuxU-LuxO (quorum sensing)
#
ALuxR family
B DctS-DctR (C4-dicarboxylate transport)
B TtrS-TtrR (tetrathionate respiration)
B FixL-FixJ (nitrogen fixation)
B SsrA-SsrB
#
AOther families
B FlrB-FlrC (polar flagellar synthesis)
B AauS-AauR (acidic amino acids utilization)
B SLN1-YPD1-SSK1/SKN7 (osmosensing)
B RpfC-RpfG (cell-to-cell signaling)
B GlnK-GlnL (glutamine utilization)
B HspS-HspR (hexose phosphates uptake)
B YesM-YesN
B CikA
B RegB-RegA (redox response)
C LILAB_11520 sensor histidine kinase K15011 regB; two-component system, sensor histidine kinase RegB [EC:2.7.13.3]
C LILAB_15320 sensor histidine kinase K15011 regB; two-component system, sensor histidine kinase RegB [EC:2.7.13.3]
C LILAB_11515 Fis family DNA-binding response regulator K15012 regA; two-component system, response regulator RegA
C LILAB_15315 Fis family DNA-binding response regulator K15012 regA; two-component system, response regulator RegA
C LILAB_06385 response regulator K15012 regA; two-component system, response regulator RegA
C LILAB_29145 response regulator K15012 regA; two-component system, response regulator RegA
B FitF-FitH (insecticidal toxin regulation)
B PhcS-PhcRQ
B SagS-HptB-HsbR (swarming activity and biofilm formation)
C LILAB_07555 sensor histidine kinase/response regulator K20974 K20974; two-component system, sensor histidine kinase [EC:2.7.13.3]
B PdtaS-PdtaR
B NasS-NasT
B Unclassified
C LILAB_31140 sensor histidine kinase/response regulator K19694 chiS; two-component system, sensor histidine kinase ChiS
C LILAB_23605 sensor protein K11527 K11527; two-component system, sensor histidine kinase and response regulator [EC:2.7.13.3]
C LILAB_22650 sensor protein K11527 K11527; two-component system, sensor histidine kinase and response regulator [EC:2.7.13.3]
C LILAB_30295 putative response regulator/sensor histidine kinase K11527 K11527; two-component system, sensor histidine kinase and response regulator [EC:2.7.13.3]
!
#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: December 14, 2023