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Transfer RNA Biogenesis - Mycobacterium sp. MCS
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AEukaryotic type
B 5'processing factors
C Ribonucrease P
B 3'processing and CCA adding factors
C 3'processing factors
D Mmcs_3506 beta-lactamase-like protein K00784 rnz; ribonuclease Z [EC:3.1.26.11]
C CCA adding factors
B tRNA spricing factors
C tRNA splicing endonuclease complex
C tRNA splicing ligase complex
C Other tRNA splicing factors
B tRNA transport factors
C tRNA export factors
C tRNA import factors
B Aminoacyl-tRNA synthetases (AARSs)
C Multi-aminoacyl-tRNA synthetase complex (MSC)
D Mmcs_1919 glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D Mmcs_4941 Glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D Mmcs_2076 prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D Mmcs_3100 Isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D Mmcs_5389 leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D Mmcs_4266 methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D Mmcs_3898 arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D Mmcs_4758 lysyl-tRNA synthetase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D Mmcs_2983 lysyl-tRNA synthetase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D Mmcs_2308 aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
C Other AARSs
D Mmcs_2346 alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D Mmcs_3445 glycyl-tRNA synthetase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D Mmcs_2242 Ser-tRNA(Thr) hydrolase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D Mmcs_5029 seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D Mmcs_4737 cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D Mmcs_3558 valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D Mmcs_2285 histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D Mmcs_2974 phenylalanyl-tRNA synthetase, alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D Mmcs_2973 phenylalanyl-tRNA synthetase beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D Mmcs_2955 tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D Mmcs_1212 tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
C Trans-editing factors
D Mmcs_3321 D-tyrosyl-tRNA(Tyr) deacylase K07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
C AARS associated factors
D Mmcs_3954 histidine triad (HIT) protein K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
B tRNA modification factors
C Deaminases
C Dihydorouridine synthases
C Methylthiotransferase
C Methyltransferases
D Mmcs_3136 tRNA (adenine-58-N(1)-) methyltransferase K07442 TRM61; tRNA (adenine57-N1/adenine58-N1)-methyltransferase catalytic subunit [EC:2.1.1.219 2.1.1.220]
D Mmcs_0173 conserved hypothetical protein K03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]
C Psudouridine synthases
D Mmcs_1115 tRNA pseudouridine synthase A K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D Mmcs_2095 tRNA pseudouridine synthase B K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
C Thiolation factors
D Mmcs_1875 aminotransferase, class V K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
C KEOPS/EKC complex
C Elongator complex
C Elongator related proteins
C Other tRNA modification factors
D Mmcs_3885 translation factor SUA5 K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D Mmcs_2162 tRNA delta(2)-isopentenylpyrophosphate transferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
D Mmcs_5214 selenophosphate synthase K01008 selD; selenide, water dikinase [EC:2.7.9.3]
B tRNA degradation factors
C TRAMP complex
C Rapid tRNA decay (RTD) pathway factors
D Mmcs_3154 inositol monophosphatase K01082 cysQ; 3'(2'), 5'-bisphosphate nucleotidase [EC:3.1.3.7]
D Mmcs_3917 inositol monophosphatase K01082 cysQ; 3'(2'), 5'-bisphosphate nucleotidase [EC:3.1.3.7]
C Other tRNA degradation factors
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AProkaryotic type
B 5'processing factors
C Ribonucrease P
D Mmcs_5412 ribonuclease P protein component K03536 rnpA; ribonuclease P protein component [EC:3.1.26.5]
D Mmcs_R0029 rnpB; RNA component of RNaseP K01978 rnpB; M1 RNA
B 3'processing and CCA adding factors
C 3'processing factors
D Mmcs_3506 beta-lactamase-like protein K00784 rnz; ribonuclease Z [EC:3.1.26.11]
D Mmcs_3844 RNAse PH K00989 rph; ribonuclease PH [EC:2.7.7.56]
D Mmcs_2210 3'-5' exonuclease K03684 rnd; ribonuclease D [EC:3.1.13.5]
C CCA adding factors
B tRNA spricing factors
C tRNA splicing endonucleases
C tRNA splicing ligases
C Other tRNA splicing factors
B tRNA transport factors
C tRNA export factors
B Aminoacyl-tRNA synthetases (AARSs)
C Multi-aminoacyl-tRNA synthetase complex (MSC)
D Mmcs_5389 leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D Mmcs_2076 prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
C Other AARSs
D Mmcs_2955 tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D Mmcs_1212 tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D Mmcs_2242 Ser-tRNA(Thr) hydrolase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D Mmcs_3100 Isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D Mmcs_4758 lysyl-tRNA synthetase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D Mmcs_2983 lysyl-tRNA synthetase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D Mmcs_2346 alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D Mmcs_3558 valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D Mmcs_4266 methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D Mmcs_5029 seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D Mmcs_2308 aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D Mmcs_4737 cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D Mmcs_1919 glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D Mmcs_4941 Glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D Mmcs_3898 arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D Mmcs_2974 phenylalanyl-tRNA synthetase, alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D Mmcs_2973 phenylalanyl-tRNA synthetase beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D Mmcs_2285 histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
C Trans-editing factors
D Mmcs_3321 D-tyrosyl-tRNA(Tyr) deacylase K07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
D Mmcs_1378 conserved hypothetical protein K03976 ybaK; Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase [EC:3.1.1.-]
B tRNA modification factors
C Deaminases
D Mmcs_4960 tRNA-adenosine deaminase K11991 tadA; tRNA(adenine34) deaminase [EC:3.5.4.33]
C Dihydorouridine synthases
C Methylthiotransferases
D Mmcs_2157 tRNA-i(6)A37 thiotransferase enzyme MiaB K06168 miaB; tRNA-2-methylthio-N6-dimethylallyladenosine synthase [EC:2.8.4.3]
C Methyltransferases
D Mmcs_0173 conserved hypothetical protein K03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]
D Mmcs_1968 tRNA (Guanine37-N(1)-) methyltransferase K00554 trmD; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]
D Mmcs_1186 tRNA/rRNA methyltransferase (SpoU) K03216 trmL; tRNA (cytidine/uridine-2'-O-)-methyltransferase [EC:2.1.1.207]
D Mmcs_2978 tRNA/rRNA methyltransferase (SpoU) K03437 spoU; RNA methyltransferase, TrmH family
C Psudouridine synthases
D Mmcs_1115 tRNA pseudouridine synthase A K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D Mmcs_2095 tRNA pseudouridine synthase B K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
D Mmcs_1251 pseudouridine synthase K06177 rluA; tRNA pseudouridine32 synthase / 23S rRNA pseudouridine746 synthase [EC:5.4.99.28 5.4.99.29]
C Thiolation factors
D Mmcs_1876 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]
D Mmcs_1875 aminotransferase, class V K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D Mmcs_4536 glycine cleavage T protein (aminomethyl transferase) K06980 ygfZ; tRNA-modifying protein YgfZ
C KEOPS/EKC complex
C Other tRNA modification factors
D Mmcs_2162 tRNA delta(2)-isopentenylpyrophosphate transferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
D Mmcs_5214 selenophosphate synthase K01008 selD; selenide, water dikinase [EC:2.7.9.3]
D Mmcs_4948 tRNA-guanine transglycosylase K00773 tgt; queuine tRNA-ribosyltransferase [EC:2.4.2.29]
D Mmcs_4776 tRNA(Ile)-lysidine synthetase-like protein K04075 tilS; tRNA(Ile)-lysidine synthase [EC:6.3.4.19]
D Mmcs_1149 peptidase M22, glycoprotease K14742 tsaB; tRNA threonylcarbamoyladenosine biosynthesis protein TsaB
D Mmcs_3885 translation factor SUA5 K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D Mmcs_1151 O-sialoglycoprotein endopeptidase K25706 tsaD; tRNA N6-adenosine threonylcarbamoyltransferase [EC:2.3.1.234]
D Mmcs_1148 protein of unknown function UPF0079 K06925 tsaE; tRNA threonylcarbamoyladenosine biosynthesis protein TsaE
B tRNA degradation factors
C Mmcs_2100 Polyribonucleotide nucleotidyltransferase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: February 29, 2024