+F Repair protein KO #

  DNA Repair and Recombination Proteins - Maylandia zebra (zebra mbuna)

% ! AEukaryotic type B SSBR (single strand breaks repair) C Direct repair D 101480876 mgmt; methylated-DNA--protein-cysteine methyltransferase isoform X1 K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63] D 101485138 alkbh2; DNA oxidative demethylase ALKBH2 K10859 ALKBH2; DNA oxidative demethylase [EC:1.14.11.33] D 101486257 alkbh3; alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 K10860 ALKBH3; mRNA N1-methyladenine demethylase [EC:1.14.11.54] D 101471535 ascc3; activating signal cointegrator 1 complex subunit 3 K18663 ASCC3; activating signal cointegrator complex subunit 3 [EC:5.6.2.4] D 101472520 deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3] C BER (base exicision repair) D DNA glycosylases E 101485409 ung; uracil-DNA glycosylase isoform X1 K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27] E 101478181 ccno; cyclin-O K10861 UDG2; uracil-DNA glycosylase 2 [EC:3.2.2.-] E 101483821 G/T mismatch-specific thymine DNA glycosylase isoform X1 K20813 TDG; thymine-DNA glycosylase [EC:3.2.2.29] E 101484631 G/T mismatch-specific thymine DNA glycosylase K20813 TDG; thymine-DNA glycosylase [EC:3.2.2.29] E 101478861 mpg; DNA-3-methyladenine glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21] E 101469528 smug1; single-strand selective monofunctional uracil DNA glycosylase K10800 SMUG1; single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-] E 101474699 mutyh; adenine DNA glycosylase isoform X1 K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31] E 101484756 mbd4; methyl-CpG-binding domain protein 4 K10801 MBD4; methyl-CpG-binding domain protein 4 [EC:3.2.2.-] E 101475812 ogg1; N-glycosylase/DNA lyase K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18] E 101474128 neil1; endonuclease 8-like 1 isoform X1 K10567 NEIL1; endonuclease VIII-like 1 [EC:3.2.2.- 4.2.99.18] E 101465661 neil3; endonuclease 8-like 3 isoform X1 K10569 NEIL3; endonuclease VIII-like 3 [EC:3.2.2.- 4.2.99.18] E 101469961 nthl1; endonuclease III-like protein 1 isoform X1 K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] D AP endonucleases E 101472544 apex1; DNA-(apurinic or apyrimidinic site) lyase K10771 APEX1; AP endonuclease 1 [EC:3.1.11.2] E 101485194 uncharacterized protein LOC101485194 K10771 APEX1; AP endonuclease 1 [EC:3.1.11.2] E 101465054 apex2; DNA-(apurinic or apyrimidinic site) lyase 2 K10772 APEX2; AP endonuclease 2 [EC:3.1.11.2] D Long Patch-BER factors E DNA polymerase delta complex F 101484970 pold1; DNA polymerase delta catalytic subunit K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7] F 101465712 pold2; DNA polymerase delta subunit 2 K02328 POLD2; DNA polymerase delta subunit 2 F 101470862 pold3; DNA polymerase delta subunit 3 K03504 POLD3; DNA polymerase delta subunit 3 F 101483406 pold4; DNA polymerase delta subunit 4 K03505 POLD4; DNA polymerase delta subunit 4 E DNA polymerase epsilon complex F 101477333 pole; DNA polymerase epsilon catalytic subunit A K02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7] F 101463678 pole2; DNA polymerase epsilon subunit 2 K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7] F 101472104 pole3; DNA polymerase epsilon subunit 3 K02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7] F 101474498 pole4; DNA polymerase epsilon subunit 4 K03506 POLE4; DNA polymerase epsilon subunit 4 [EC:2.7.7.7] E 101482883 pcna; proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen E 101485698 probable flap endonuclease 1 homolog isoform X1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-] E 101478964 fen1; flap endonuclease 1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-] E 101479550 lig1; DNA ligase 1 K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7] D Short Patch-BER factors E 101474836 polb; DNA polymerase beta K02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-] E 101472637 xrcc1; DNA repair protein XRCC1 K10803 XRCC1; DNA-repair protein XRCC1 E 101481263 lig3; DNA ligase 3 K10776 LIG3; DNA ligase 3 [EC:6.5.1.1] D Other BER factors E 101475183 tdp1; tyrosyl-DNA phosphodiesterase 1 K10862 TDP1; tyrosyl-DNA phosphodiesterase 1 [EC:3.1.4.-] E 101466233 aptx; aprataxin isoform X1 K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72] E 101464435 aplf; aprataxin and PNK-like factor K13295 APLF; aprataxin and PNK-like factor [EC:3.1.-.-] E 101480033 pnkp; bifunctional polynucleotide phosphatase/kinase K08073 PNKP; bifunctional polynucleotide phosphatase/kinase [EC:3.1.3.32 2.7.1.78] E 101478854 high mobility group protein B1 K10802 HMGB1; high mobility group protein B1 E 101465110 high mobility group protein B1 K10802 HMGB1; high mobility group protein B1 E 101473944 poll; DNA polymerase lambda K03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-] E 101472874 parp1; poly [ADP-ribose] polymerase 1 K24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30] E 101468994 parp2; poly [ADP-ribose] polymerase 2 isoform X1 K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30] E 101484653 parp3; poly [ADP-ribose] polymerase 3 isoform X1 K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30] E 101473411 parp4; poly [ADP-ribose] polymerase 4 isoform X1 K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30] C NER (nucleotide excision repair) D GGR (global genome repair) factors E XPC-HR23B-CETN2 complex F 101465861 xpc; DNA repair protein complementing XP-C cells isoform X1 K10838 XPC; xeroderma pigmentosum group C-complementing protein F 101485882 rad23a; UV excision repair protein RAD23 homolog A K10839 RAD23; UV excision repair protein RAD23 F 101465619 UV excision repair protein RAD23 homolog B isoform X1 K10839 RAD23; UV excision repair protein RAD23 F 101467275 rad23b; UV excision repair protein RAD23 homolog B isoform X1 K10839 RAD23; UV excision repair protein RAD23 F 101480437 caltractin K10840 CETN2; centrin-2 E Cul4-DDB2 complex F 101480103 rbx1; E3 ubiquitin-protein ligase RBX1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32] F 101485787 cullin-4B K10609 CUL4; cullin 4 F 101482497 cul4b; cullin-4B K10609 CUL4; cullin 4 F 101485195 ddb1; DNA damage-binding protein 1 K10610 DDB1; DNA damage-binding protein 1 F 101480006 ddb2; DNA damage-binding protein 2 isoform X1 K10140 DDB2; DNA damage-binding protein 2 E NER4 complex D TCR (transcription coupled repair) factors E DNA-directed RNA polymerase II complex F 101464637 polr2a; DNA-directed RNA polymerase II subunit RPB1 K03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6] F 101470057 polr2b; DNA-directed RNA polymerase II subunit RPB2 K03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6] F 101473474 polr2c; DNA-directed RNA polymerase II subunit RPB3 K03011 RPB3; DNA-directed RNA polymerase II subunit RPB3 F 101467986 polr2d; DNA-directed RNA polymerase II subunit RPB4 K03012 RPB4; DNA-directed RNA polymerase II subunit RPB4 F 101481657 polr2e; DNA-directed RNA polymerases I, II, and III subunit RPABC1 K03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1 F 101483512 polr2f; DNA-directed RNA polymerases I, II, and III subunit RPABC2 K03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2 F 101472304 polr2g; DNA-directed RNA polymerase II subunit RPB7 K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7 F 101486540 polr2h; DNA-directed RNA polymerases I, II, and III subunit RPABC3 K03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3 F 101473584 polr2i; DNA-directed RNA polymerase II subunit RPB9 K03017 RPB9; DNA-directed RNA polymerase II subunit RPB9 F 101474549 polr2l; DNA-directed RNA polymerases I, II, and III subunit RPABC5 K03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5 F 101486043 polr2j; DNA-directed RNA polymerase II subunit RPB11-a K03008 RPB11; DNA-directed RNA polymerase II subunit RPB11 F 101476521 polr2k; DNA-directed RNA polymerases I, II, and III subunit RPABC4 K03009 RPABC4; DNA-directed RNA polymerases I, II, and III subunit RPABC4 E Cul4-CSA complex F 101480103 rbx1; E3 ubiquitin-protein ligase RBX1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32] F 101485787 cullin-4B K10609 CUL4; cullin 4 F 101482497 cul4b; cullin-4B K10609 CUL4; cullin 4 F 101485195 ddb1; DNA damage-binding protein 1 K10610 DDB1; DNA damage-binding protein 1 F 101473009 ercc8; DNA excision repair protein ERCC-8 K10570 ERCC8; DNA excision repair protein ERCC-8 E Other TCR factor F 101480982 ercc6; DNA excision repair protein ERCC-6 isoform X1 K10841 ERCC6; DNA excision repair protein ERCC-6 F 101476148 uvssa; UV-stimulated scaffold protein A isoform X1 K23720 UVSSA; UV-stimulated scaffold protein A F 101466944 transcription elongation factor 1 homolog K25829 ELOF1; transcription elongation factor 1 F 101466659 transcription elongation factor 1 homolog K25829 ELOF1; transcription elongation factor 1 D TFIIH complex E 101466679 ercc3; general transcription and DNA repair factor IIH helicase subunit XPB isoform X1 K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4] E 101487140 ercc2; general transcription and DNA repair factor IIH helicase subunit XPD K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3] E 101465554 gtf2h1; general transcription factor IIH subunit 1 K03141 TFIIH1; transcription initiation factor TFIIH subunit 1 E 101466805 general transcription factor IIH subunit 2 K03142 TFIIH2; transcription initiation factor TFIIH subunit 2 E 101465917 gtf2h3; general transcription factor IIH subunit 3 K03143 TFIIH3; transcription initiation factor TFIIH subunit 3 E 101487923 gtf2h4; general transcription factor IIH subunit 4 K03144 TFIIH4; transcription initiation factor TFIIH subunit 4 E 101477796 general transcription factor IIH subunit 5 K10845 TTDA; TFIIH basal transcription factor complex TTD-A subunit E 112436042 gtf2h5; general transcription factor IIH subunit 5 K10845 TTDA; TFIIH basal transcription factor complex TTD-A subunit E 101463697 cdk7; cyclin-dependent kinase 7 K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23] E 101473484 ccnh; cyclin-H isoform X1 K06634 CCNH; cyclin H E 101484546 mnat1; CDK-activating kinase assembly factor MAT1 K10842 MNAT1; CDK-activating kinase assembly factor MAT1 D RPA (replication factor A) E 101481258 replication protein A 70 kDa DNA-binding subunit K07466 RFA1; replication factor A1 E 101468816 rpa1; replication protein A 70 kDa DNA-binding subunit isoform X1 K07466 RFA1; replication factor A1 E 101474004 rpa2; replication protein A 32 kDa subunit isoform X1 K10739 RFA2; replication factor A2 E 101480808 rpa3; replication protein A 14 kDa subunit K10740 RPA3; replication factor A3 D Other NER factors E 101483722 xpa; DNA repair protein complementing XP-A cells K10847 XPA; DNA-repair protein complementing XP-A cells E 101468887 ercc1; DNA excision repair protein ERCC-1 K10849 ERCC1; DNA excision repair protein ERCC-1 E 101464731 ercc4; DNA repair endonuclease XPF K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-] E 101480257 ercc5; DNA repair protein complementing XP-G cells K10846 ERCC5; DNA excision repair protein ERCC-5 E 101479550 lig1; DNA ligase 1 K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7] E 101472565 mms19; MMS19 nucleotide excision repair protein homolog K15075 MET18; DNA repair/transcription protein MET18/MMS19 E 101481184 cullin-3 K03869 CUL3; cullin 3 E 101466095 cullin-3 isoform X1 K03869 CUL3; cullin 3 E 101470783 cullin-5 isoform X1 K10612 CUL5; cullin 5 E 101465747 cul5; cullin-5 isoform X1 K10612 CUL5; cullin 5 E 101488090 eloc; elongin-C K03872 ELOC; elongin-C E 101469837 elongin-B isoform X1 K03873 ELOB; elongin-B E 101480389 elongin-B K03873 ELOB; elongin-B E 101480953 eloa; elongin-A K15076 ELOA; elongin-A E 101467343 ubiquitin-associated protein 2 isoform X1 K26545 UBAP2; ubiquitin-associated protein 2 E 101477455 ubap2l; ubiquitin-associated protein 2-like isoform X1 K26545 UBAP2; ubiquitin-associated protein 2 E 101463995 ubap2; ubiquitin-associated protein 2 K26545 UBAP2; ubiquitin-associated protein 2 C MMR (mismatch excision repair) D Mismatch and loop recognition factors E 101484075 msh2; DNA mismatch repair protein Msh2 K08735 MSH2; DNA mismatch repair protein MSH2 E 101481912 msh3; DNA mismatch repair protein Msh3 isoform X1 K08736 MSH3; DNA mismatch repair protein MSH3 E 101470032 msh6; DNA mismatch repair protein Msh6 isoform X1 K08737 MSH6; DNA mismatch repair protein MSH6 D MutL homologs E 101488039 pms1; PMS1 protein homolog 1 K10864 PMS1; DNA mismatch repair protein PMS1 E 101485199 mlh1; DNA mismatch repair protein Mlh1 isoform X1 K08734 MLH1; DNA mismatch repair protein MLH1 E 101483314 pms2; mismatch repair endonuclease PMS2 K10858 PMS2; DNA mismatch repair protein PMS2 E 101467524 mlh3; DNA mismatch repair protein Mlh3 isoform X1 K08739 MLH3; DNA mismatch repair protein MLH3 D DNA polymerase delta complex E 101484970 pold1; DNA polymerase delta catalytic subunit K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7] E 101465712 pold2; DNA polymerase delta subunit 2 K02328 POLD2; DNA polymerase delta subunit 2 E 101470862 pold3; DNA polymerase delta subunit 3 K03504 POLD3; DNA polymerase delta subunit 3 E 101483406 pold4; DNA polymerase delta subunit 4 K03505 POLD4; DNA polymerase delta subunit 4 D RPA (replication factor A) E 101481258 replication protein A 70 kDa DNA-binding subunit K07466 RFA1; replication factor A1 E 101468816 rpa1; replication protein A 70 kDa DNA-binding subunit isoform X1 K07466 RFA1; replication factor A1 E 101474004 rpa2; replication protein A 32 kDa subunit isoform X1 K10739 RFA2; replication factor A2 E 101480808 rpa3; replication protein A 14 kDa subunit K10740 RPA3; replication factor A3 D RFC (replication factor C) E 101476928 rfc1; replication factor C subunit 1 K10754 RFC1; replication factor C subunit 1 E 101487225 rfc2; replication factor C subunit 2 K10755 RFC2_4; replication factor C subunit 2/4 E 101480490 rfc4; replication factor C subunit 4 K10755 RFC2_4; replication factor C subunit 2/4 E 101484098 rfc5; replication factor C subunit 5 K10756 RFC3_5; replication factor C subunit 3/5 E 101475542 rfc3; replication factor C subunit 3 K10756 RFC3_5; replication factor C subunit 3/5 D Other MMR factors E 101482883 pcna; proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen E 101479533 exo1; exonuclease 1 K10746 EXO1; exonuclease 1 [EC:3.1.-.-] E 101478854 high mobility group protein B1 K10802 HMGB1; high mobility group protein B1 E 101465110 high mobility group protein B1 K10802 HMGB1; high mobility group protein B1 E 101479550 lig1; DNA ligase 1 K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7] E 101475006 wdr76; WD repeat-containing protein 76 isoform X1 K24755 WDR76; WD repeat-containing protein 76 B DSBR (double strand breaks repair) C HR (homologous recombination) D MRN(MRX) complex E 101479389 mre11; double-strand break repair protein MRE11 K10865 MRE11; double-strand break repair protein MRE11 E 112430055 double-strand break repair protein MRE11-like K10865 MRE11; double-strand break repair protein MRE11 E 101477643 rad50; DNA repair protein RAD50 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-] E 101482170 LOW QUALITY PROTEIN: DNA repair protein RAD50 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-] E 101467424 nbn; nibrin isoform X1 K10867 NBN; nibrin D BRCA1-core complex E 101470273 brca1; breast cancer type 1 susceptibility protein isoform X2 K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27] E 101476906 BRCA1-associated RING domain protein 1 isoform X1 K10683 BARD1; BRCA1-associated RING domain protein 1 D BRCA1-A complex E 101470273 brca1; breast cancer type 1 susceptibility protein isoform X2 K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27] E 101472962 abraxas1; BRCA1-A complex subunit Abraxas 1 K20774 FAM175A; BRCA1-A complex subunit Abraxas E 101464805 uimc1; BRCA1-A complex subunit RAP80 isoform X1 K20775 UIMC1; BRCA1-A complex subunit RAP80 E 101485912 babam1; BRISC and BRCA1-A complex member 1 K20776 BABAM; BRISC and BRCA1-A complex member 1 E 101469404 babam2; BRISC and BRCA1-A complex member 2 K12173 BRE; BRCA1-A complex subunit BRE E 101472371 brcc3; lys-63-specific deubiquitinase BRCC36 K11864 BRCC3; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-] D BRCA1-B complex E 101470273 brca1; breast cancer type 1 susceptibility protein isoform X2 K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27] E 101480812 brip1; Fanconi anemia group J protein K15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3] E 101485819 topbp1; DNA topoisomerase 2-binding protein 1 K10728 TOPBP1; topoisomerase (DNA) II binding protein 1 D BRCA1-C complex E 101470273 brca1; breast cancer type 1 susceptibility protein isoform X2 K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27] E 101469252 rbbp8; DNA endonuclease RBBP8 K20773 RBBP8; DNA endonuclease RBBP8 [EC:3.1.-.-] E 101479389 mre11; double-strand break repair protein MRE11 K10865 MRE11; double-strand break repair protein MRE11 E 112430055 double-strand break repair protein MRE11-like K10865 MRE11; double-strand break repair protein MRE11 E 101477643 rad50; DNA repair protein RAD50 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-] E 101482170 LOW QUALITY PROTEIN: DNA repair protein RAD50 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-] E 101467424 nbn; nibrin isoform X1 K10867 NBN; nibrin D BRCA complex E 101470273 brca1; breast cancer type 1 susceptibility protein isoform X2 K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27] E 101485201 brca2; breast cancer type 2 susceptibility protein K08775 BRCA2; breast cancer 2 susceptibility protein E 101466590 palb2; partner and localizer of BRCA2 isoform X1 K10897 PALB2; partner and localizer of BRCA2 E 101466567 rad51; DNA repair protein RAD51 homolog 1 K04482 RAD51; DNA repair protein RAD51 D RecA family proteins E 101466567 rad51; DNA repair protein RAD51 homolog 1 K04482 RAD51; DNA repair protein RAD51 E 101472995 DNA repair protein RAD51 homolog 3 K10870 RAD51L2; RAD51-like protein 2 E 101481547 rad51d; DNA repair protein RAD51 homolog 4 K10871 RAD51L3; RAD51-like protein 3 E 101476596 xrcc2; DNA repair protein XRCC2 K10879 XRCC2; DNA-repair protein XRCC2 E 101480481 xrcc3; DNA repair protein XRCC3 isoform X1 K10880 XRCC3; DNA-repair protein XRCC3 D Rad52 family proteins E 101463935 rad52; DNA repair protein RAD52 homolog isoform X2 K10873 RAD52; DNA repair and recombination protein RAD52 E 101480503 rdm1; RAD52 motif-containing protein 1 K10874 RDM1; RAD52 motif-containing protein 1 D Rad54 family proteins E 101471052 rad54l; DNA repair and recombination protein RAD54-like K10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-] E 101465377 helicase ARIP4 isoform X2 K10876 RAD54L2; RAD54-like protein 2 [EC:5.6.2.-] E 101468957 helicase ARIP4 isoform X1 K10876 RAD54L2; RAD54-like protein 2 [EC:5.6.2.-] E 101478906 rad54b; DNA repair and recombination protein RAD54B isoform X1 K10877 RAD54B; DNA repair and recombination protein RAD54B [EC:5.6.2.-] D RecQ family DNA helicases E 101473464 recql; ATP-dependent DNA helicase Q1 K10899 RECQL; ATP-dependent DNA helicase Q1 [EC:5.6.2.4] E 101467484 blm; Bloom syndrome protein isoform X1 K10901 BLM; bloom syndrome protein [EC:5.6.2.4] E 101469359 recql4; ATP-dependent DNA helicase Q4 K10730 RECQL4; ATP-dependent DNA helicase Q4 [EC:5.6.2.4] E 101477970 recql5; ATP-dependent DNA helicase Q5 K10902 RECQL5; ATP-dependent DNA helicase Q5 [EC:5.6.2.4] D Bloom's syndrome complex (BTR) E 101467484 blm; Bloom syndrome protein isoform X1 K10901 BLM; bloom syndrome protein [EC:5.6.2.4] E 101477098 top3a; DNA topoisomerase 3-alpha isoform X1 K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1] E 101465545 top3b; DNA topoisomerase 3-beta-1 isoform X1 K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1] E 101466600 recQ-mediated genome instability protein 1 K10990 RMI1; RecQ-mediated genome instability protein 1 E 112435649 rmi1; recQ-mediated genome instability protein 1 K10990 RMI1; RecQ-mediated genome instability protein 1 E 101486607 rmi2; recQ-mediated genome instability protein 2 K15365 RMI2; RecQ-mediated genome instability protein 2 D RPA (replication factor A) E 101481258 replication protein A 70 kDa DNA-binding subunit K07466 RFA1; replication factor A1 E 101468816 rpa1; replication protein A 70 kDa DNA-binding subunit isoform X1 K07466 RFA1; replication factor A1 E 101474004 rpa2; replication protein A 32 kDa subunit isoform X1 K10739 RFA2; replication factor A2 E 101480808 rpa3; replication protein A 14 kDa subunit K10740 RPA3; replication factor A3 D Protein phosphatase 4 E 101479584 ppp4c; serine/threonine-protein phosphatase 4 catalytic subunit K15423 PPP4C; serine/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16] E 101477628 ppp4r1; serine/threonine-protein phosphatase 4 regulatory subunit 1 K15424 PPP4R1; serine/threonine-protein phosphatase 4 regulatory subunit 1 E 101476683 ppp4r2; serine/threonine-protein phosphatase 4 regulatory subunit 2 K15425 PPP4R2; serine/threonine-protein phosphatase 4 regulatory subunit 2 E 101473203 serine/threonine-protein phosphatase 4 regulatory subunit 2-A isoform X1 K15425 PPP4R2; serine/threonine-protein phosphatase 4 regulatory subunit 2 E 101487051 ppp4r3b; serine/threonine-protein phosphatase 4 regulatory subunit 3B K17491 SMEK; protein phosphatase 4 regulatory subunit 3 E 101478173 ppp4r3a; serine/threonine-protein phosphatase 4 regulatory subunit 3A isoform X1 K17491 SMEK; protein phosphatase 4 regulatory subunit 3 E 101486304 ppp4r4; serine/threonine-protein phosphatase 4 regulatory subunit 4 isoform X1 K15426 PPP4R4; serine/threonine-protein phosphatase 4 regulatory subunit 4 D AP-5 complex E 101464724 ap5b1; AP-5 complex subunit beta-1 K19022 AP5B1; AP-5 complex subunit beta-1 E 101479482 ap5m1; AP-5 complex subunit mu-1 isoform X1 K19023 AP5M1; AP-5 complex subunit mu-1 E 101482240 ap5s1; AP-5 complex subunit sigma-1 isoform X1 K19024 AP5S1; AP-5 complex subunit sigma-1 E 101472168 ap5z1; AP-5 complex subunit zeta-1 isoform X1 K19025 AP5Z1; AP-5 complex subunit zeta-1 D SMC5-SMC6 complex E 101466491 smc6; structural maintenance of chromosomes protein 6 K22804 SMC6; structural maintenance of chromosomes protein 6 E 101484447 structural maintenance of chromosomes protein 6 K22804 SMC6; structural maintenance of chromosomes protein 6 E 101466001 fam84a; protein FAM84A K22805 FAM84A; protein FAM84A E 101477210 nsmce1; non-structural maintenance of chromosomes element 1 homolog isoform X1 K22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27] E 101479680 nsmce2; E3 SUMO-protein ligase NSE2 K22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-] E 101468845 non-structural maintenance of chromosomes element 3 homolog K22823 NSMCE3; non-structural maintenance of chromosomes element 3 E 101484804 nsmce4a; non-structural maintenance of chromosomes element 4 homolog A K22825 NSMCE4; non-structural maintenance of chromosomes element 4 E 101487427 slf1; SMC5-SMC6 complex localization factor protein 1 K26126 SLF1; SMC5-SMC6 complex localization factor protein 1 E 101485066 SMC5-SMC6 complex localization factor protein 2 isoform X7 K26127 SLF2; SMC5-SMC6 complex localization factor protein 2 D Other HR factors E 101485879 eme1; crossover junction endonuclease EME1 isoform X1 K10882 EME1; crossover junction endonuclease EME1 [EC:3.1.22.-] E 101486647 exd2; exonuclease 3'-5' domain-containing protein 2 isoform X1 K20777 EXD2; exonuclease 3'-5' domain-containing protein 2 [EC:3.1.11.1] E 101480192 mus81; crossover junction endonuclease MUS81 K08991 MUS81; crossover junction endonuclease MUS81 [EC:3.1.22.-] E 101483171 sem1; 26S proteasome complex subunit SEM1 K10881 SHFM1; 26 proteasome complex subunit DSS1 E 105940755 swi5; DNA repair protein SWI5 homolog K10991 SWI5; DNA repair protein Swi5/Sae3 E 101486878 sfr1; swi5-dependent recombination DNA repair protein 1 homolog K10992 SFR1; Swi5-dependent recombination DNA repair protein 1 E 101485547 structure-specific endonuclease subunit slx1 isoform X1 K15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-] E 101482848 slx4; structure-specific endonuclease subunit SLX4 K10484 BTBD12; structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12) E 101485245 gen1; flap endonuclease GEN homolog 1 K15338 GEN1; holliday junction resolvase GEN1/YEN1 [EC:3.1.-.-] E 101471266 LOW QUALITY PROTEIN: spatacsin K19026 SPG11; spatacsin E 112433901 LOW QUALITY PROTEIN: spatacsin-like K19026 SPG11; spatacsin E 101479936 zfyve26; zinc finger FYVE domain-containing protein 26 isoform X1 K19027 ZFYVE26; zinc finger FYVE domain-containing protein 26 E 101478475 rad51ap1; RAD51-associated protein 1 isoform X1 K20778 RAD51AP1; RAD51-associated protein 1 E 101464050 mortality factor 4-like protein 1 K11339 MORF4L1; mortality factor 4-like protein 1 E 101483484 mortality factor 4-like protein 1 isoform X1 K11339 MORF4L1; mortality factor 4-like protein 1 E 112431023 deoxynucleoside triphosphate triphosphohydrolase SAMHD1-like K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-] E 112431515 deoxynucleoside triphosphate triphosphohydrolase SAMHD1-like K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-] E 112431516 deoxynucleoside triphosphate triphosphohydrolase SAMHD1-like K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-] E 112431518 deoxynucleoside triphosphate triphosphohydrolase SAMHD1-like K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-] E 101466315 samhd1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-] E 101465723 deoxynucleoside triphosphate triphosphohydrolase SAMHD1-like K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-] E 112436638 deoxynucleoside triphosphate triphosphohydrolase SAMHD1-like isoform X1 K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-] E 112436673 uncharacterized protein LOC112436673 K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-] E 101467667 deoxynucleoside triphosphate triphosphohydrolase SAMHD1-like K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-] E 101485914 fignl1; fidgetin-like protein 1 isoform X2 K22766 FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-] E 101463588 spidr; DNA repair-scaffolding protein isoform X1 K22806 SPIDR; DNA repair-scaffolding protein E 101479966 protein FAM84B K22810 FAM84B; protein FAM84B E 101479597 protein FAM84B K22810 FAM84B; protein FAM84B E 101474552 brat1; BRCA1-associated ATM activator 1 K23112 BRAT1; BRCA1-associated ATM activator 1 E 101484289 lg18h21orf2; protein C21orf2 isoform X1 K23456 CFAP410; cilla- and flagella-associated protein E 101481066 hdgfl2; hepatoma-derived growth factor-related protein 2 K25065 HDGFL2; hepatoma-derived growth factor-related protein 2 E 101468890 zswim7; zinc finger SWIM domain-containing protein 7 K25770 ZSWIM7; zinc finger SWIM domain-containing protein 7 E 101464738 ATPase SWSAP1 K25771 SWSAP1; ATPase SWSAP1 E 101484239 emsy; BRCA2-interacting transcriptional repressor EMSY isoform X1 K25790 EMSY; BRCA2-interacting transcriptional repressor EMSY E 101483999 hsf2bp; heat shock factor 2-binding protein isoform X1 K25791 HSF2BP; heat shock factor 2-binding protein E 101474539 mms22l; protein MMS22-like K26125 MMS22L; protein MMS22-like E 101472281 tonsoku-like protein isoform X2 K09257 NFKBIL2; NF-kappa-B inhibitor-like protein 2 E 101477250 LOW QUALITY PROTEIN: biorientation of chromosomes in cell division protein 1-like 1 K27262 BOD1L1; biorientation of chromosomes in cell division protein 1-like 1 E 101476795 parpbp; PCNA-interacting partner K27412 PARPBP; PCNA-interacting partner C NHEJ (non-homologous end-joining) D DNA-PK complex E 101471101 xrcc6; X-ray repair cross-complementing protein 6 K10884 XRCC6; ATP-dependent DNA helicase 2 subunit 1 E 101486802 xrcc5; X-ray repair cross-complementing protein 5 K10885 XRCC5; ATP-dependent DNA helicase 2 subunit 2 E 101484851 prkdc; DNA-dependent protein kinase catalytic subunit K06642 PRKDC; DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1] D MRX complex E 101479389 mre11; double-strand break repair protein MRE11 K10865 MRE11; double-strand break repair protein MRE11 E 112430055 double-strand break repair protein MRE11-like K10865 MRE11; double-strand break repair protein MRE11 E 101477643 rad50; DNA repair protein RAD50 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-] E 101482170 LOW QUALITY PROTEIN: DNA repair protein RAD50 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-] D DNA Ligase 4 complex E 101465742 lig4; DNA ligase 4 K10777 LIG4; DNA ligase 4 [EC:6.5.1.1] E 101475616 xrcc4; DNA repair protein XRCC4 K10886 XRCC4; DNA-repair protein XRCC4 E 101481251 DNA repair protein XRCC4 K10886 XRCC4; DNA-repair protein XRCC4 E 101470251 nhej1; non-homologous end-joining factor 1 K10980 NHEJ1; non-homologous end-joining factor 1 D X-family DNA polymerases E 101473944 poll; DNA polymerase lambda K03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-] E 101475122 polm; DNA-directed DNA/RNA polymerase mu K03513 POLM; DNA polymerase mu [EC:2.7.7.7] E 101468990 dntt; DNA nucleotidylexotransferase K00977 DNTT; DNA nucleotidylexotransferase [EC:2.7.7.31] E 101474836 polb; DNA polymerase beta K02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-] D Other NHEJ factors E 101466233 aptx; aprataxin isoform X1 K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72] E 101464435 aplf; aprataxin and PNK-like factor K13295 APLF; aprataxin and PNK-like factor [EC:3.1.-.-] E 101469690 dclre1c; protein artemis isoform X1 K10887 DCLRE1C; DNA cross-link repair 1C protein [EC:3.1.-.-] E 106676806 tyrosyl-DNA phosphodiesterase 2 K19619 TDP2; tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-] E 105940876 tyrosyl-DNA phosphodiesterase 2 K19619 TDP2; tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-] E 112430138 tyrosyl-DNA phosphodiesterase 2-like K19619 TDP2; tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-] E 106676723 LOW QUALITY PROTEIN: tyrosyl-DNA phosphodiesterase 2 K19619 TDP2; tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-] E 101487742 tdp2; tyrosyl-DNA phosphodiesterase 2 isoform X1 K19619 TDP2; tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-] E 101470005 tyrosyl-DNA phosphodiesterase 2-like K19619 TDP2; tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-] E 101482681 smchd1; structural maintenance of chromosomes flexible hinge domain-containing protein 1 isoform X1 K23113 SMCHD1; structural maintenance of chromosomes flexible hinge domain-containing protein 1 E 101478897 PWWP domain-containing protein MUM1 K23386 PWWP3; PWWP domain-containing DNA repair factor 3 E 101464783 paxx; protein PAXX K25772 PAXX; protein PAXX E 101480984 jmjd8; jmjC domain-containing protein 8 K25792 JMJD8; jumonji domain-containing protein 8 E 105940574 fam35a; protein FAM35A K26129 SHLD2; shieldin complex subunit 2 E 101480102 uncharacterized protein FLJ26957 isoform X1 K26130 SHLD3; shieldin complex subunit 3 C FA (Fanconi anemia) pathway D FA core complex E 101469234 fanca; Fanconi anemia group A protein isoform X1 K10888 FANCA; fanconi anemia group A protein E 101487672 fancb; Fanconi anemia group B protein isoform X1 K10889 FANCB; fanconi anemia group B protein E 101483934 fancc; Fanconi anemia group C protein isoform X2 K10890 FANCC; fanconi anemia group C protein E 101464808 fance; Fanconi anemia group E protein isoform X2 K10892 FANCE; fanconi anemia group E protein E 101466042 fancf; Fanconi anemia group F protein K10893 FANCF; fanconi anemia group F protein E 101468350 fancg; Fanconi anemia group G protein isoform X1 K10894 FANCG; fanconi anemia group G protein E 101487178 fancl; E3 ubiquitin-protein ligase FANCL K10606 FANCL; E3 ubiquitin-protein ligase FANCL [EC:2.3.2.27] E 101479658 fancm; Fanconi anemia group M protein isoform X1 K10896 FANCM; fanconi anemia group M protein E 101467362 faap24; Fanconi anemia core complex-associated protein 24 K10898 FAAP24; fanconi anemia-associated protein E 101486055 faap100; Fanconi anemia core complex-associated protein 100 isoform X1 K10993 FAAP100; fanconi anemia core complex 100 kDa subunit D FA core complex binding factors E 101479362 hes1; transcription factor HES-1 K06054 HES1; hairy and enhancer of split 1 E 101482682 transcription factor HES-1-B K06054 HES1; hairy and enhancer of split 1 E 101470131 hes4; transcription factor HES-4 isoform X1 K06054 HES1; hairy and enhancer of split 1 E 101487346 centromere protein S K11511 APITD1; centromere protein S E 101465202 cenpx; centromere protein X K15360 STRA13; centromere protein X E 101483587 ube2t; ubiquitin-conjugating enzyme E2 T K13960 UBE2T; ubiquitin-conjugating enzyme E2 T [EC:2.3.2.23] D Bloom's syndrome complex (BTR) E 101467484 blm; Bloom syndrome protein isoform X1 K10901 BLM; bloom syndrome protein [EC:5.6.2.4] E 101477098 top3a; DNA topoisomerase 3-alpha isoform X1 K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1] E 101465545 top3b; DNA topoisomerase 3-beta-1 isoform X1 K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1] E 101466600 recQ-mediated genome instability protein 1 K10990 RMI1; RecQ-mediated genome instability protein 1 E 112435649 rmi1; recQ-mediated genome instability protein 1 K10990 RMI1; RecQ-mediated genome instability protein 1 E 101486607 rmi2; recQ-mediated genome instability protein 2 K15365 RMI2; RecQ-mediated genome instability protein 2 D FANCD2-I complex E 101485873 fancd2; Fanconi anemia group D2 protein K10891 FANCD2; fanconi anemia group D2 protein E 101486550 fanci; Fanconi anemia group I protein isoform X1 K10895 FANCI; fanconi anemia group I protein D Downstream FA components E 101470273 brca1; breast cancer type 1 susceptibility protein isoform X2 K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27] E 101485201 brca2; breast cancer type 2 susceptibility protein K08775 BRCA2; breast cancer 2 susceptibility protein E 101480812 brip1; Fanconi anemia group J protein K15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3] E 101466590 palb2; partner and localizer of BRCA2 isoform X1 K10897 PALB2; partner and localizer of BRCA2 D Other FA pathway factors E 101469341 fan1; fanconi-associated nuclease 1 K15363 FAN1; fanconi-associated nuclease 1 [EC:3.1.21.- 3.1.4.1] E 101466567 rad51; DNA repair protein RAD51 homolog 1 K04482 RAD51; DNA repair protein RAD51 E 101472995 DNA repair protein RAD51 homolog 3 K10870 RAD51L2; RAD51-like protein 2 E 101471500 telo2; telomere length regulation protein TEL2 homolog K11137 TELO2; telomere length regulation protein E 101483960 usp1; ubiquitin carboxyl-terminal hydrolase 1 isoform X1 K11832 USP1; ubiquitin carboxyl-terminal hydrolase 1 [EC:3.4.19.12] E 101474352 wdr48; WD repeat-containing protein 48 isoform X1 K15361 WDR48; WD repeat-containing protein 48 C Other DSBR factors D Protein phosphatase 6 E 101475652 serine/threonine-protein phosphatase 6 catalytic subunit K15498 PPP6C; serine/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16] E 101468714 serine/threonine-protein phosphatase 6 catalytic subunit K15498 PPP6C; serine/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16] E 101480002 serine/threonine-protein phosphatase 6 regulatory subunit 2 K15500 PPP6R2; serine/threonine-protein phosphatase 6 regulatory subunit 2 E 101464791 ppp6r2; serine/threonine-protein phosphatase 6 regulatory subunit 2 isoform X1 K15500 PPP6R2; serine/threonine-protein phosphatase 6 regulatory subunit 2 E 101470727 ppp6r3; serine/threonine-protein phosphatase 6 regulatory subunit 3 isoform X2 K15501 PPP6R3; serine/threonine-protein phosphatase 6 regulatory subunit 3 E 101466190 ankrd28; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A K15502 ANKRD28; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A E 101466422 serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X1 K15502 ANKRD28; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A E 101478932 ankrd44; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B K15503 ANKRD44; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B E 101485004 ankrd52; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C K15504 ANKRD52; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C E 101484379 serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C K15504 ANKRD52; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C D Ubiquitin ligases E 101484971 rnf8; E3 ubiquitin-protein ligase RNF8 isoform X1 K10667 RNF8; E3 ubiquitin-protein ligase RNF8 [EC:2.3.2.27] E 101484320 rnf168; E3 ubiquitin-protein ligase RNF168 K20779 RNF168; E3 ubiquitin-protein ligase RNF168 [EC:2.3.2.31] E 101471265 rnf169; E3 ubiquitin-protein ligase RNF169 K20805 RNF169; E3 ubiquitin-protein ligase RNF169 [EC:2.3.2.31] E 101466252 E3 ubiquitin-protein ligase HERC2 isoform X1 K10595 HERC2; E3 ubiquitin-protein ligase HERC2 [EC:2.3.2.26] D Others E 101463814 wrap53; telomerase Cajal body protein 1 isoform X1 K23314 WRAP53; telomerase Cajal body protein 1 E 101481775 tprn; taperin K24164 TPRN; taperin E 101483224 wdr70; WD repeat-containing protein 70 K24752 WDR70; WD repeat-containing protein 70 E 101475006 wdr76; WD repeat-containing protein 76 isoform X1 K24755 WDR76; WD repeat-containing protein 76 B TLS (translesion DNA synthesis) factors C Y-family DNA polymerases D 101471183 polh; DNA polymerase eta K03509 POLH; DNA polymerase eta [EC:2.7.7.7] D 101478772 poli; DNA polymerase iota isoform X1 K03510 POLI; DNA polymerase iota [EC:2.7.7.7] D 101481221 polk; DNA polymerase kappa K03511 POLK; DNA polymerase kappa [EC:2.7.7.7] D 101470115 rev1; DNA repair protein REV1 isoform X1 K03515 REV1; DNA repair protein REV1 [EC:2.7.7.-] C B-family DNA polymerases D 101466576 rev3l; DNA polymerase zeta catalytic subunit K02350 REV3L; DNA polymerase zeta [EC:2.7.7.7] C A-family DNA polymerase C Rad6 epistasis group D 101488085 ube2a; ubiquitin-conjugating enzyme E2 A isoform X1 K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23] D 101480967 ubiquitin-conjugating enzyme E2 A K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23] D 101470340 ube2b; ubiquitin-conjugating enzyme E2 B K10574 UBE2B; ubiquitin-conjugating enzyme E2 B [EC:2.3.2.23] D 101483336 rad18; E3 ubiquitin-protein ligase RAD18 K10627 RAD18; E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27] D 101474248 hltf; helicase-like transcription factor K15711 SMARCA3; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3 [EC:5.6.2. 2.3.2.27] D 101474603 ubiquitin-conjugating enzyme E2 variant 1 isoform X1 K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant D 105940822 ubiquitin-conjugating enzyme E2 variant 1 isoform X1 K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant D 101464370 ube2v2; ubiquitin-conjugating enzyme E2 variant 2 K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant D 101468522 ube2n; ubiquitin-conjugating enzyme E2 N K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23] D 101482995 ubiquitin-conjugating enzyme E2 N K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23] C Other TLS factors D 101482883 pcna; proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen D 101476795 parpbp; PCNA-interacting partner K27412 PARPBP; PCNA-interacting partner D 101484498 sprtn; sprT-like domain-containing protein Spartan K24051 SPRTN; SprT-like domain-contaning protein Spartan D 101480145 acidic repeat-containing protein K26957 GCNA; germ cell nuclear acidic protein B Check point factors C Rad9-Hus1-Rad1 complex D 101466591 rad9a; cell cycle checkpoint control protein RAD9A K10994 RAD9A; cell cycle checkpoint control protein RAD9A [EC:3.1.11.2] D 101478084 rad9b; cell cycle checkpoint control protein RAD9B isoform X1 K10995 RAD9B; cell cycle checkpoint control protein RAD9B D 101478483 hus1; checkpoint protein HUS1 K10903 HUS1; HUS1 checkpoint protein D 101476026 rad1; cell cycle checkpoint protein RAD1 K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2] C HRAD17(Rad24)-RFC complex D 101473728 rad17; cell cycle checkpoint protein RAD17 K06662 HRAD17; cell cycle checkpoint protein D 101487225 rfc2; replication factor C subunit 2 K10755 RFC2_4; replication factor C subunit 2/4 D 101480490 rfc4; replication factor C subunit 4 K10755 RFC2_4; replication factor C subunit 2/4 D 101484098 rfc5; replication factor C subunit 5 K10756 RFC3_5; replication factor C subunit 3/5 D 101475542 rfc3; replication factor C subunit 3 K10756 RFC3_5; replication factor C subunit 3/5 C Rad17-Mec3-Ddc1 complex D 101476026 rad1; cell cycle checkpoint protein RAD1 K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2] C FPC (fork protection complex) D 101478453 timeless; protein timeless homolog K10997 TIMELESS; replication fork protection complex subunit TIMELESS/Tof1/Swi1 D 112433862 TIMELESS-interacting protein-like K10998 TIPIN; replication fork protection complex subunit TIPIN/Csm3/Swi3 D 112434231 TIMELESS-interacting protein-like K10998 TIPIN; replication fork protection complex subunit TIPIN/Csm3/Swi3 D 101483176 clspn; claspin isoform X2 K25773 CLSPN; claspin C Triple T complex D 101471500 telo2; telomere length regulation protein TEL2 homolog K11137 TELO2; telomere length regulation protein D 101471847 TELO2-interacting protein 1 homolog K20403 TTI1; TELO2-interacting protein 1 D 101478663 tti2; TELO2-interacting protein 2 K23115 TTI2; TELO2-interacting protein 2 C BAG6-UBL4A-GET4 complex D 101469368 large proline-rich protein BAG6 isoform X1 K23390 BAG6; large proline-rich protein BAG6 D 101474331 large proline-rich protein BAG6 isoform X1 K23390 BAG6; large proline-rich protein BAG6 D 101469798 ubiquitin-like protein 4A K23388 UBL4; ubiquitin-like protein 4 D 101471884 get4; Golgi to ER traffic protein 4 homolog isoform X1 K23387 GET4; golgi to ER traffic protein 4 C Other check point factors D 101475692 atr; serine/threonine-protein kinase ATR isoform X1 K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1] D 101479222 atrip; ATR-interacting protein isoform X1 K10905 ATRIP; ATR interacting protein D 101485570 atm; serine-protein kinase ATM K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1] D 112435930 serine-protein kinase ATM-like K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1] D 101480650 cellular tumor antigen p53 K04451 TP53; tumor protein p53 D 112432676 serine/arginine repetitive matrix protein 1-like isoform X1 K04451 TP53; tumor protein p53 D 101487018 chek1; serine/threonine-protein kinase Chk1 K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1] D 101485707 chek2; serine/threonine-protein kinase Chk2 K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1] D 101482927 M-phase inducer phosphatase 1 isoform X1 K05866 CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48] D 101473746 14-3-3 protein zeta K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta D 101471951 14-3-3 protein beta/alpha-A K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta D 101468055 14-3-3 protein beta/alpha K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta D 101484489 14-3-3 protein beta/alpha-A K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta D 101481383 14-3-3 protein zeta/delta K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta D 101481074 14-3-3 protein gamma-1 K16198 YWHAG_H; 14-3-3 protein gamma/eta D 101483393 14-3-3 protein gamma-B K16198 YWHAG_H; 14-3-3 protein gamma/eta D 101468387 14-3-3 protein epsilon isoform X1 K06630 YWHAE; 14-3-3 protein epsilon D 101470309 14-3-3 protein epsilon isoform X1 K06630 YWHAE; 14-3-3 protein epsilon D 101465443 nav2; neuron navigator 2 isoform X1 K19483 NAV2; neuron navigator 2 [EC:5.6.2.4] D 101474252 wee1; wee1-like protein kinase K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1] D 101475313 wee1-like protein kinase 2 isoform X1 K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1] D 101484910 per1; period circadian protein homolog 1 K21944 PER1; period circadian protein 1 D 101465886 per2; period circadian protein homolog 2 K02633 PER2; period circadian protein 2 D 101485591 period circadian protein homolog 2 isoform X1 K02633 PER2; period circadian protein 2 D 101479865 LOW QUALITY PROTEIN: period circadian protein homolog 3 K21945 PER3; period circadian protein 3 D 101468968 mdc1; mediator of DNA damage checkpoint protein 1 isoform X1 K20780 MDC1; mediator of DNA damage checkpoint protein 1 D 101485852 plastin-3 K17336 PLS3; plastin-3 D 101477359 plastin-3 K17336 PLS3; plastin-3 D 101487596 apoptosis-enhancing nuclease K18340 AEN; apoptosis-enhancing nuclease [EC:3.1.-.-] D 101475303 plk3; serine/threonine-protein kinase PLK3 K08862 PLK3; polo-like kinase 3 [EC:2.7.11.21] D 101481225 nek4; serine/threonine-protein kinase Nek4 isoform X1 K08857 NEK1_4_5; serine/threonine-protein kinase Nek1/4/5 [EC:2.7.11.1] D 101475406 serine/threonine-protein kinase Nek5 isoform X1 K08857 NEK1_4_5; serine/threonine-protein kinase Nek1/4/5 [EC:2.7.11.1] D 101481667 nek1; serine/threonine-protein kinase Nek1 isoform X1 K08857 NEK1_4_5; serine/threonine-protein kinase Nek1/4/5 [EC:2.7.11.1] D 101477302 nek10; serine/threonine-protein kinase Nek10 isoform X1 K20879 NEK10; serine/threonine-protein kinase Nek10 [EC:2.7.11.1] D 101486861 nek11; serine/threonine-protein kinase Nek11 K20880 NEK11; serine/threonine-protein kinase Nek11 [EC:2.7.11.1] D 101485672 donson; protein downstream neighbor of Son K22422 DONSON; protein downstream neighbor of Son D 101464450 kank3; KN motif and ankyrin repeat domain-containing protein 3 K22808 KANK; KN motif and ankyrin repeat domain-containing protein D 101473236 kank2; KN motif and ankyrin repeat domain-containing protein 2 K22808 KANK; KN motif and ankyrin repeat domain-containing protein D 101477576 kank1; KN motif and ankyrin repeat domain-containing protein 1 K22808 KANK; KN motif and ankyrin repeat domain-containing protein D 101482378 KN motif and ankyrin repeat domain-containing protein 4 isoform X1 K22808 KANK; KN motif and ankyrin repeat domain-containing protein D 101482809 kank4; KN motif and ankyrin repeat domain-containing protein 4 isoform X2 K22808 KANK; KN motif and ankyrin repeat domain-containing protein D 101485722 KN motif and ankyrin repeat domain-containing protein 1 isoform X1 K22808 KANK; KN motif and ankyrin repeat domain-containing protein D 101475424 charged multivesicular body protein 4c K24782 CHMP4C; charged multivesicular body protein 4C D 101470270 vacuolar protein sorting-associated protein 4A K12196 VPS4; vacuolar protein-sorting-associated protein 4 D 101468536 vps4b; vacuolar protein sorting-associated protein 4B isoform X1 K12196 VPS4; vacuolar protein-sorting-associated protein 4 D 101481666 vacuolar protein sorting-associated protein 4B K12196 VPS4; vacuolar protein-sorting-associated protein 4 D 101474896 zfyve19; abscission/NoCut checkpoint regulator K24778 ZFYVE19; abscission/NoCut checkpoint regulator D 101473325 replication stress response regulator SDE2 isoform X1 K25059 SDE2; replication stress response regulator SDE2 D 112434962 LOW QUALITY PROTEIN: replication stress response regulator SDE2-like K25059 SDE2; replication stress response regulator SDE2 B Other factors with a suspected DNA repair function C DNA polymerases D 101471421 DNA polymerase theta isoform X2 K02349 POLQ; DNA polymerase theta [EC:2.7.7.7] D 101465492 mybbp1a; myb-binding protein 1A K02331 POL5; DNA polymerase phi [EC:2.7.7.7] D 101482310 primpol; DNA-directed primase/polymerase protein K22761 PRIMPOL; DNA-directed primase/polymerase protein [EC:2.7.7.102 2.7.7.7] C Nucleases D 101473964 dclre1a; DNA cross-link repair 1A protein K15340 DCLRE1A; DNA cross-link repair 1A protein D 101484429 dclre1b; 5' exonuclease Apollo K15341 DCLRE1B; DNA cross-link repair 1B protein [EC:3.1.-.-] D 101473359 endov; endonuclease V isoform X1 K21813 ENDOV; endonuclease V [EC:3.1.26.-] D 101478593 DNA annealing helicase and endonuclease ZRANB3 K25861 ZRANB3; DNA annealing helicase and endonuclease ZRANB3 [EC:5.6.2.- 3.1.-.-] D 101465114 ankle1; ankyrin repeat and LEM domain-containing protein 1 isoform X1 K21411 ANKLE1; ankyrin repeat and LEM domain-containing protein 1 C Helicases D 101471791 helq; helicase POLQ-like K19178 HELQ; POLQ-like helicase [EC:5.6.2.4] D 101469256 ercc6l2; DNA excision repair protein ERCC-6-like 2 isoform X1 K20098 ERCC6L2; DNA excision repair protein ERCC-6-like 2 [EC:5.6.2.-] C PSO4 complex D 101465618 prpf19; pre-mRNA-processing factor 19 K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27] D 106674712 cell division cycle 5-like protein K12860 CDC5L; pre-mRNA-splicing factor CDC5/CEF1 D 101487762 cdc5l; cell division cycle 5-like protein K12860 CDC5L; pre-mRNA-splicing factor CDC5/CEF1 D 101476998 LOW QUALITY PROTEIN: pre-mRNA-splicing factor SPF27 K12861 BCAS2; pre-mRNA-splicing factor SPF27 D 112430101 pre-mRNA-splicing factor SPF27-like K12861 BCAS2; pre-mRNA-splicing factor SPF27 D 101484377 plrg1; pleiotropic regulator 1 K12862 PLRG1; pleiotropic regulator 1 C Modulation of nucleotide pools D 101474582 nudt15; nucleotide triphosphate diphosphatase NUDT15 K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D 101466444 nudt1; 7,8-dihydro-8-oxoguanine triphosphatase K17816 NUDT1; 8-oxo-dGTP diphosphatase / 2-hydroxy-dATP diphosphatase [EC:3.6.1.55 3.6.1.56] D 101476216 nudt18; 8-oxo-dGDP phosphatase NUDT18 isoform X1 K17817 NUDT18; 8-oxo-dGDP phosphatase [EC:3.6.1.58] D 101473379 dut; deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial isoform X2 K01520 dut; dUTP diphosphatase [EC:3.6.1.23] D 101476861 ribonucleoside-diphosphate reductase large subunit K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1] D 101481005 ribonucleoside-diphosphate reductase large subunit K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1] D 101468603 ribonucleoside-diphosphate reductase subunit M2 K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1] D 101469208 ribonucleoside-diphosphate reductase subunit M2 K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1] D 101479048 rrm2b; ribonucleoside-diphosphate reductase subunit M2 B K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1] # AProkaryotic type B SSBR (single strand breaks repair) C Direct repair D 101480876 mgmt; methylated-DNA--protein-cysteine methyltransferase isoform X1 K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63] D 101472520 deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3] C BER (base exicision repair) D DNA glycosylases E 101485409 ung; uracil-DNA glycosylase isoform X1 K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27] E 101469528 smug1; single-strand selective monofunctional uracil DNA glycosylase K10800 SMUG1; single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-] E 101478861 mpg; DNA-3-methyladenine glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21] E 101474699 mutyh; adenine DNA glycosylase isoform X1 K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31] E 101469961 nthl1; endonuclease III-like protein 1 isoform X1 K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] D AP endonucleases D RecJ D DNA ligase D DNA polymerase I C NER (nucleotide excision repair) D GGR (global genome repair) factors D TCR (transcription coupled repair) factors E DNA-directed RNA polymerase complex (RNAP) E TRCF (transcription-repair coupling factor) C MMR (mismatch excision repair) D Mismatch and loop recognition factors D Molecular matchmaker D Strand discrimination factor D DNA exonucleases D DNA polymerase III holoenzyme D DNA ligase D Other MMR factors E 101481042 ssbp1; single-stranded DNA-binding protein, mitochondrial K03111 ssb; single-strand DNA-binding protein B DSBR (double strand breaks repair) C HR (homologous recombination) D RecBC pathway proteins D RecFOR pathway proteins D AddAB pathway proteins D Other HR factor D Archaeal homologous recombinant proteins C NHEJ (non-homologous end-joining) D Two-component NHEJ DNA repair complex D SHIIR (short-homology-independent illegitimate recombination) E Facilitator E Supressor D SHDIR (short-homology-dependent illegitimate recombination) E RecET pathway E Facilitator E Supressor B TLS (translesion DNA synthesis) factors C Y-family DNA polymerases C Other SOS response factors D 101481042 ssbp1; single-stranded DNA-binding protein, mitochondrial K03111 ssb; single-strand DNA-binding protein B Other factors with a suspected DNA repair function C DNA polymerase C DNA helicases C Modulation of nucleotide pools D 101474582 nudt15; nucleotide triphosphate diphosphatase NUDT15 K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D 101473379 dut; deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial isoform X2 K01520 dut; dUTP diphosphatase [EC:3.6.1.23] C Others ! #
#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024