+E Replication protein KO
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DNA Replication Proteins - Pocillopora damicornis (lace coral)
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AEukaryotic type
B DNA Replication Initiation Factors
C pre-RC (pre-replication complex)
D 113678358 LOW QUALITY PROTEIN: origin recognition complex subunit 1-like K02603 ORC1; origin recognition complex subunit 1
D 113680850 origin recognition complex subunit 2-like K02604 ORC2; origin recognition complex subunit 2
D 113686972 origin recognition complex subunit 3-like isoform X1 K02605 ORC3; origin recognition complex subunit 3
D 113685761 origin recognition complex subunit 4-like K02606 ORC4; origin recognition complex subunit 4
D 113664183 origin recognition complex subunit 5-like K02607 ORC5; origin recognition complex subunit 5
D 113679499 origin recognition complex subunit 6-like isoform X1 K02608 ORC6; origin recognition complex subunit 6
D 113675020 DNA replication factor Cdt1-like K10727 CDT1; chromatin licensing and DNA replication factor 1
D 113681969 cell division control protein 6 homolog K02213 CDC6; cell division control protein 6
D 113685958 LOW QUALITY PROTEIN: DNA replication licensing factor mcm2-like K02540 MCM2; DNA replication licensing factor MCM2 [EC:5.6.2.3]
D 113666833 DNA replication licensing factor MCM3-like K02541 MCM3; DNA replication licensing factor MCM3 [EC:5.6.2.3]
D 113665928 DNA replication licensing factor mcm4-A-like K02212 MCM4; DNA replication licensing factor MCM4 [EC:5.6.2.3]
D 113667782 DNA replication licensing factor mcm5-A-like K02209 MCM5; DNA replication licensing factor MCM5 [EC:5.6.2.3]
D 113687043 zygotic DNA replication licensing factor mcm6-A-like K02542 MCM6; DNA replication licensing factor MCM6 [EC:5.6.2.3]
D 113676303 DNA replication licensing factor mcm7-like K02210 MCM7; DNA replication licensing factor MCM7 [EC:5.6.2.3]
C CDK (cyclin dependent kinase)
D 113684509 G2/mitotic-specific cyclin-A-like K06627 CCNA; cyclin-A
D 113680591 G1/S-specific cyclin-E1-like K06626 CCNE; G1/S-specific cyclin-E1
D 113685713 cyclin-dependent kinase 2-like K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
C DDK (Dbf-4 dependent kinase)
D 113670250 cell division cycle 7-related protein kinase-like K02214 CDC7; cell division control protein 7 [EC:2.7.11.1]
C GINS complex
D 113673144 DNA replication complex GINS protein PSF1-like K10732 GINS1; GINS complex subunit 1
D 113685430 DNA replication complex GINS protein PSF2-like K10733 GINS2; GINS complex subunit 2
D 113667532 DNA replication complex GINS protein PSF3-like K10734 GINS3; GINS complex subunit 3
D 113670514 DNA replication complex GINS protein SLD5-like K10735 GINS4; GINS complex subunit 4
C Other initiation factors
D 113667817 DNA topoisomerase 2-binding protein 1-A-like K10728 TOPBP1; topoisomerase (DNA) II binding protein 1
D 113665933 ATP-dependent DNA helicase Q4-like K10730 RECQL4; ATP-dependent DNA helicase Q4 [EC:5.6.2.4]
D 113675491 cell division control protein 45 homolog K06628 CDC45; cell division control protein 45
D 113682824 DNA helicase MCM8-like K10737 MCM8; DNA helicase MCM8 [EC:5.6.2.4]
D 113682791 DNA helicase MCM9-like K10738 MCM9; DNA helicase MCM9 [EC:5.6.2.4]
D 113664477 protein MCM10 homolog K10736 MCM10; minichromosome maintenance protein 10
D 113678848 DNA helicase B-like K15254 HELB; DNA helicase B [EC:5.6.2.3]
D 113682681 cyclin-dependent kinase 2-interacting protein-like K26052 CINP; cyclin-dependent kinase 2-interacting protein
D 113685415 mdm2-binding protein-like K26116 MTBP; Mdm2-binding protein
D 113679837 treslin-like K26117 TICRR; Treslin
B DNA Replication Elongation Factors
C DNA polymerase alpha / primase complex
D 113686295 LOW QUALITY PROTEIN: DNA polymerase alpha catalytic subunit-like K02320 POLA1; DNA polymerase alpha subunit A [EC:2.7.7.7]
D 113667156 DNA polymerase alpha subunit B-like K02321 POLA2; DNA polymerase alpha subunit B
D 113677336 DNA primase small subunit-like K02684 PRI1; DNA primase small subunit [EC:2.7.7.102]
C DNA polymerase epsilon complex
D 113682003 DNA polymerase epsilon catalytic subunit A-like K02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
D 113677660 DNA polymerase epsilon subunit 2-like K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
D 113676992 DNA polymerase epsilon subunit 3-like K02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
D 113668916 DNA polymerase epsilon subunit 4-like K03506 POLE4; DNA polymerase epsilon subunit 4 [EC:2.7.7.7]
C DNA polymerase delta complex
D 113669343 DNA polymerase delta catalytic subunit-like K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
D 113671449 DNA polymerase delta subunit 2-like K02328 POLD2; DNA polymerase delta subunit 2
D 113666570 DNA polymerase delta subunit 3-like K03504 POLD3; DNA polymerase delta subunit 3
D 113681025 DNA polymerase delta subunit 4-like K03505 POLD4; DNA polymerase delta subunit 4
C DNA polymerase gamma complex (mitochondrial)
D 113675718 DNA polymerase subunit gamma-1-like K02332 POLG; DNA polymerase gamma 1 [EC:2.7.7.7]
D 113683266 DNA polymerase subunit gamma-2, mitochondrial-like K02333 POLG2; DNA polymerase gamma 2
C RPA (replication protein A)
D 113668892 replication protein A 70 kDa DNA-binding subunit-like K07466 RFA1; replication factor A1
D 113675583 replication protein A 32 kDa subunit-B-like K10739 RFA2; replication factor A2
D 113665418 replication protein A 14 kDa subunit-like K10740 RPA3; replication factor A3
C RFC (replication factor C)
D 113678008 replication factor C subunit 1-like isoform X1 K10754 RFC1; replication factor C subunit 1
D 113686757 replication factor C subunit 2-like K10755 RFC2_4; replication factor C subunit 2/4
D 113668756 replication factor C subunit 4-like K10755 RFC2_4; replication factor C subunit 2/4
D 113681921 replication factor C subunit 3-like K10756 RFC3_5; replication factor C subunit 3/5
D 113684398 replication factor C subunit 5-like K10756 RFC3_5; replication factor C subunit 3/5
C RNase H
D 113673388 ribonuclease H1-like K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D 113684343 ribonuclease H2 subunit A-like K10743 RNASEH2A; ribonuclease H2 subunit A [EC:3.1.26.4]
D 113673997 ribonuclease H2 subunit B-like K10744 RNASEH2B; ribonuclease H2 subunit B
D 113664280 ribonuclease H2 subunit C-like K10745 RNASEH2C; ribonuclease H2 subunit C
C Other elongation factors
D 113681913 proliferating cell nuclear antigen-like K04802 PCNA; proliferating cell nuclear antigen
D 113685680 DNA replication ATP-dependent helicase/nuclease DNA2-like K10742 DNA2; DNA replication ATP-dependent helicase/nuclease Dna2 [EC:5.6.2.3 3.1.-.-]
D 113675218 flap endonuclease 1-like isoform X1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D 113676040 exonuclease 1-like K10746 EXO1; exonuclease 1 [EC:3.1.-.-]
D 113674639 DNA annealing helicase and endonuclease ZRANB3-like K25861 ZRANB3; DNA annealing helicase and endonuclease ZRANB3 [EC:5.6.2.- 3.1.-.-]
D 113671519 DNA ligase 1-like isoform X1 K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
D 113684711 ATPase family AAA domain-containing protein 5-like K26118 ATAD5; ATPase family AAA domain-containing protein 5
B DNA Replication Termination Factors
C DNA methylation enzymes
D 113679953 LOW QUALITY PROTEIN: DNA (cytosine-5)-methyltransferase 1-like K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
C Prevention of re-replication factors
D 113673701 geminin-like K10749 GMNN; geminin
D 113683543 G2/mitotic-specific cyclin-B-like K21770 CCNB2; G2/mitotic-specific cyclin-B2
D 113686326 G2/mitotic-specific cyclin-B3-like K21771 CCNB3; G2/mitotic-specific cyclin-B3
D 113674739 cyclin-dependent kinase 1-like K02087 CDK1; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
C Telomere proteins
D Shelterin complex
E 113680077 uncharacterized protein LOC113680077 K11109 POT1; protection of telomeres protein 1
E 113686443 LOW QUALITY PROTEIN: protection of telomeres protein 1-like K11109 POT1; protection of telomeres protein 1
E 113669839 telomeric repeat-binding factor 2-like isoform X1 K11111 TERF2; telomeric repeat-binding factor 2
E 113664189 telomeric repeat-binding factor 2-interacting protein 1-like K11113 TERF2IP; telomeric repeat-binding factor 2-interacting protein 1
D TERB1-TERB2-MAJIN complex
E 113677239 telomere repeats-binding bouquet formation protein 1-like isoform X1 K25749 TERB1; telomere repeats-binding bouquet formation protein 1
E 113672932 uncharacterized protein LOC113672932 K25750 TERB2; telomere repeats-binding bouquet formation protein 2
E 113667249 membrane-anchored junction protein-like K25751 MAJIN; membrane-anchored junction protein
D CST complex (animals)
E 113682305 CST complex subunit CTC1-like isoform X1 K23311 CTC1; CST complex subunit CTC1
E 113677467 CST complex subunit STN1-like isoform X1 K23312 STN1; CST complex subunit STN1
E 113686285 CST complex subunit TEN1-like K23313 TEN1; CST complex subunit TEN1
D CST complex (yeast)
D RIF proteins
D SIR proteins
C Telomerase complex (animals)
D 113679467 telomerase-binding protein EST1A-like K11124 SMG6; protein SMG6 [EC:3.1.-.-]
D 113672642 protein SMG5-like K11125 SMG5; protein SMG5
D 113684973 telomerase reverse transcriptase-like K11126 TERT; telomerase reverse transcriptase [EC:2.7.7.49]
D Dyskerin complex
E 113683745 H/ACA ribonucleoprotein complex subunit 1-like K11128 GAR1; H/ACA ribonucleoprotein complex subunit 1
E 113677593 H/ACA ribonucleoprotein complex subunit 2-like protein K11129 NHP2; H/ACA ribonucleoprotein complex subunit 2
E 113680412 H/ACA ribonucleoprotein complex subunit cbf5-like K11131 DKC1; H/ACA ribonucleoprotein complex subunit 4 [EC:5.4.99.-]
C Telomerase complex (fungi)
D 113684973 telomerase reverse transcriptase-like K11126 TERT; telomerase reverse transcriptase [EC:2.7.7.49]
D Sm core complex
E 113670502 small nuclear ribonucleoprotein-associated protein B'-like K11086 SNRPB; small nuclear ribonucleoprotein B and B'
E 113668423 small nuclear ribonucleoprotein Sm D1-like K11087 SNRPD1; small nuclear ribonucleoprotein D1
E 113681506 small nuclear ribonucleoprotein Sm D2 K11096 SNRPD2; small nuclear ribonucleoprotein D2
E 113676751 small nuclear ribonucleoprotein Sm D3-like K11088 SNRPD3; small nuclear ribonucleoprotein D3
E 113673476 small nuclear ribonucleoprotein E-like K11097 SNRPE; small nuclear ribonucleoprotein E
E 113682973 small nuclear ribonucleoprotein F K11098 SNRPF; small nuclear ribonucleoprotein F
E 113676464 small nuclear ribonucleoprotein G-like K11099 SNRPG; small nuclear ribonucleoprotein G
C ELG1-RFC complex
D 113686757 replication factor C subunit 2-like K10755 RFC2_4; replication factor C subunit 2/4
D 113668756 replication factor C subunit 4-like K10755 RFC2_4; replication factor C subunit 2/4
D 113681921 replication factor C subunit 3-like K10756 RFC3_5; replication factor C subunit 3/5
D 113684398 replication factor C subunit 5-like K10756 RFC3_5; replication factor C subunit 3/5
C MRN complex
D 113676169 double-strand break repair protein MRE11-like K10865 MRE11; double-strand break repair protein MRE11
D 113683551 DNA repair protein RAD50-like K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
D 113664576 nibrin-like K10867 NBN; nibrin
C Other termination factors
D 113683099 Werner syndrome ATP-dependent helicase-like isoform X1 K10900 WRN; werner syndrome ATP-dependent helicase [EC:5.6.2.4]
D 113673640 DNA-dependent protein kinase catalytic subunit-like K06642 PRKDC; DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1]
D 113672809 poly [ADP-ribose] polymerase 1-like K24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]
D 113674225 poly [ADP-ribose] polymerase 2-like K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
D 113678812 poly [ADP-ribose] polymerase 4-like K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
D 113667456 tankyrase-2-like K10799 TNKS; tankyrase [EC:2.4.2.30]
D 113666469 PIN2/TERF1-interacting telomerase inhibitor 1-like K11135 PINX1; Pin2-interacting protein X1
D 113665169 regulator of telomere elongation helicase 1-like K11136 RTEL1; regulator of telomere elongation helicase 1 [EC:5.6.2.3]
D 113675427 telomere length regulation protein TEL2 homolog K11137 TELO2; telomere length regulation protein
D 113676542 telomere-associated protein RIF1-like K11138 RIF1; telomere-associated protein RIF1
D 113680454 LOW QUALITY PROTEIN: ATP-dependent DNA helicase PIF6-like K15255 PIF1; ATP-dependent DNA helicase PIF1 [EC:5.6.2.3]
D 113678503 ATP-dependent DNA helicase PIF1-like K15255 PIF1; ATP-dependent DNA helicase PIF1 [EC:5.6.2.3]
D 113680594 transcriptional activator protein Pur-beta-like K21772 PURA; transcriptional activator protein Pur-alpha
D 113682018 telomerase Cajal body protein 1-like K23314 WRAP53; telomerase Cajal body protein 1
D 113671008 replication stress response regulator SDE2-like K25059 SDE2; replication stress response regulator SDE2
B DNA Topoisomerases
C 113673955 DNA topoisomerase I, mitochondrial-like K03163 TOP1; DNA topoisomerase I [EC:5.6.2.1]
C 113677346 DNA topoisomerase 2-alpha-like K03164 TOP2; DNA topoisomerase II [EC:5.6.2.2]
C 113669086 DNA topoisomerase 3-beta-1-like K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
C 113674928 DNA topoisomerase 3-alpha-like K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
#
AProkaryotic type
B DNA Replication Initiation Factors
C Initiation factors (bacterial)
D 113683096 single-stranded DNA-binding protein, mitochondrial-like K03111 ssb; single-strand DNA-binding protein
C Initiation factors (archaeal)
B DNA Replication Elongation Factors
C Elongation factors (bacterial)
D DNA polymerase III holoenzyme
D RNase H
E 113673388 ribonuclease H1-like K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D Other elongation factors
C Elongation factors (archaeal)
D B-family DNA polymerases
D D-family DNA polymerases
D RNase H
E 113673388 ribonuclease H1-like K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D RFC (replication factor C)
D Other elongation factors
E 113685680 DNA replication ATP-dependent helicase/nuclease DNA2-like K10742 DNA2; DNA replication ATP-dependent helicase/nuclease Dna2 [EC:5.6.2.3 3.1.-.-]
E 113675218 flap endonuclease 1-like isoform X1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
E 113671519 DNA ligase 1-like isoform X1 K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
B DNA Replication Termination Factors
C Terminus site-binding protein
C DNA methylation enzymes
C Prevention of re-replication factors
B DNA Topoisomerases
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: November 2, 2022