+E Ubiquitin system KO
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Ubiquitin System - Meyerozyma guilliermondii
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AUbiquitins and ubiquitin-like proteins
B Ubiquitins
C PGUG_02244 ubiquitin K08770 UBC; ubiquitin C
C PGUG_01234 60S ribosomal protein L40 K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e
C PGUG_04476 ubiquitin K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae
B Ubiquitin-like proteins (UBLs)
C PGUG_02445 hypothetical protein K12158 NEDD8; ubiquitin-like protein Nedd8
C PGUG_01565 similar to Paz2 K08341 GABARAP; GABA(A) receptor-associated protein
C PGUG_03606 hypothetical protein K08336 ATG12; ubiquitin-like protein ATG12
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AUbiquitin-activating enzymes (E1)
B Ubiquitin activating enzyme
C PGUG_04230 ubiquitin-activating enzyme E1 1 K03178 UBE1; ubiquitin-activating enzyme E1 [EC:6.2.1.45]
B UBL-activating enzymes
C PGUG_00106 hypothetical protein K10684 UBLE1A; ubiquitin-like 1-activating enzyme E1 A [EC:6.2.1.45]
C PGUG_04430 hypothetical protein K10685 UBLE1B; ubiquitin-like 1-activating enzyme E1 B [EC:6.2.1.45]
C PGUG_02938 hypothetical protein K10686 UBA3; NEDD8-activating enzyme E1 [EC:6.2.1.64]
C PGUG_02424 hypothetical protein K04532 NAE1; NEDD8-activating enzyme E1 regulatory subunit
C PGUG_04417 hypothetical protein K11996 MOCS3; adenylyltransferase and sulfurtransferase [EC:2.7.7.80 2.8.1.11]
C PGUG_04077 hypothetical protein K08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7
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AUbiquitin-conjugating enzymes (E2)
B Ubiquitin-conjugating enzymes
C PGUG_05641 ubiquitin-conjugating enzyme E2 2 K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
C PGUG_02879 ubiquitin-conjugating enzyme E2 4 K06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]
C PGUG_01594 similar to ubiquitin conjugating enzyme K04555 UBE2G2; ubiquitin-conjugating enzyme E2 G2 [EC:2.3.2.23]
C PGUG_00773 similar to ubiquitin-conjugating enzyme K10576 UBE2H; ubiquitin-conjugating enzyme E2 H [EC:2.3.2.23]
C PGUG_02008 hypothetical protein K04554 UBE2J2; ubiquitin-conjugating enzyme E2 J2 [EC:2.3.2.23]
C PGUG_04018 hypothetical protein K04649 UBE2K; ubiquitin-conjugating enzyme (huntingtin interacting protein 2) [EC:2.3.2.23]
C PGUG_05697 similar to ubiquitin-conjugating enzyme K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C PGUG_05826 hypothetical protein K02207 UBE2R; ubiquitin-conjugating enzyme E2 R [EC:2.3.2.23]
C PGUG_04836 hypothetical protein K10688 UBE2W; ubiquitin-conjugating enzyme E2 W [EC:2.3.2.23 2.3.2.25]
C PGUG_00521 hypothetical protein K10689 PEX4; peroxin-4 [EC:2.3.2.23]
B UBL-conjugating enzymes
C PGUG_01945 hypothetical protein K10577 UBE2I; ubiquitin-conjugating enzyme E2 I
C PGUG_04693 hypothetical protein K08343 ATG3; ubiquitin-like-conjugating enzyme ATG3
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AUbiquitin ligases (E3)
B HECT type E3
C PGUG_02508 hypothetical protein K10589 UBE3C; ubiquitin-protein ligase E3 C [EC:2.3.2.26]
C PGUG_01331 hypothetical protein K20803 UBE3D; ubiquitin-protein ligase E3 D [EC:2.3.2.26]
C PGUG_05073 hypothetical protein K10590 TRIP12; E3 ubiquitin-protein ligase TRIP12 [EC:2.3.2.26]
C PGUG_01556 hypothetical protein K10591 NEDD4; E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26]
C PGUG_02920 hypothetical protein K10592 HUWE1; E3 ubiquitin-protein ligase HUWE1 [EC:2.3.2.26]
C PGUG_00870 hypothetical protein K12232 HECTD2; E3 ubiquitin-protein ligase HECTD2 [EC:2.3.2.26]
C HECT type E3 associated proteins
B U-box type E3
C PGUG_02380 hypothetical protein K10597 UBE4B; ubiquitin conjugation factor E4 B [EC:2.3.2.27]
C PGUG_00199 hypothetical protein K09561 STUB1; STIP1 homology and U-box containing protein 1 [EC:2.3.2.27]
C PGUG_04170 hypothetical protein K09561 STUB1; STIP1 homology and U-box containing protein 1 [EC:2.3.2.27]
C PGUG_02228 hypothetical protein K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]
B Single Ring-finger type E3
C BRE1 proteins
D PGUG_02180 hypothetical protein K10696 BRE1; E3 ubiquitin-protein ligase BRE1 [EC:2.3.2.27]
C CBL proteins
C SINA (Seven in absentia) proteins
C Ligand of Numb proteins
C March proteins
D PGUG_02476 hypothetical protein K10661 MARCH6; E3 ubiquitin-protein ligase MARCH6 [EC:2.3.2.27]
C MDM2/MDM4 proteins
C NFX1 proteins
D PGUG_03871 hypothetical protein K12236 NFX1; transcriptional repressor NF-X1
C Pellino proteins
C Peripheral membrane proteins
D PGUG_01510 hypothetical protein K13346 PEX10; peroxin-10
D PGUG_04932 hypothetical protein K13345 PEX12; peroxin-12
D PGUG_05098 hypothetical protein K06664 PEX2; peroxin-2
C RBR proteins
D PGUG_02554 hypothetical protein K11968 ARIH1; ariadne-1 [EC:2.3.2.31]
D PGUG_02152 hypothetical protein K11971 RNF14; E3 ubiquitin-protein ligase RNF14 [EC:2.3.2.31]
C TRAF proteins
C TRIM/RBCC proteins
C UBR box proteins
D PGUG_02394 hypothetical protein K10625 UBR1; E3 ubiquitin-protein ligase UBR1 [EC:2.3.2.27]
D PGUG_02392 hypothetical protein K10625 UBR1; E3 ubiquitin-protein ligase UBR1 [EC:2.3.2.27]
D PGUG_02393 hypothetical protein K10625 UBR1; E3 ubiquitin-protein ligase UBR1 [EC:2.3.2.27]
D PGUG_00347 hypothetical protein K11979 UBR7; E3 ubiquitin-protein ligase UBR7 [EC:2.3.2.27]
C ATL proteins
C Other single Ring-finger type E3
D PGUG_05283 hypothetical protein K10632 BRAP; BRCA1-associated protein [EC:2.3.2.27]
D PGUG_00304 hypothetical protein K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]
D PGUG_01244 hypothetical protein K22377 LTN1; E3 ubiquitin-protein ligase listerin [EC:2.3.2.27]
D PGUG_00892 hypothetical protein K10627 RAD18; E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27]
D PGUG_01371 hypothetical protein K26979 RNF10; E3 ubiquitin-protein ligase RNF10 [EC:2.3.2.27]
D PGUG_02678 hypothetical protein K11984 SART1; U4/U6.U5 tri-snRNP-associated protein 1
D PGUG_00451 hypothetical protein K15710 SHPRH; E3 ubiquitin-protein ligase SHPRH [EC:5.6.2.- 2.3.2.27]
D PGUG_00344 hypothetical protein K10601 SYVN1; E3 ubiquitin-protein ligase synoviolin [EC:2.3.2.27]
D PGUG_05567 hypothetical protein K10601 SYVN1; E3 ubiquitin-protein ligase synoviolin [EC:2.3.2.27]
D PGUG_04194 hypothetical protein K22381 ZNF598; E3 ubiquitin-protein ligase ZNF598 [EC:2.3.2.27]
D PGUG_02423 hypothetical protein K16275 BAH; E3 ubiquitin-protein ligase BAH [EC:2.3.2.27]
D PGUG_00931 hypothetical protein K23788 TUL1; transmembrane E3 ubiquitin-protein ligase [EC:2.3.2.27]
D PGUG_02867 hypothetical protein K23788 TUL1; transmembrane E3 ubiquitin-protein ligase [EC:2.3.2.27]
D PGUG_01644 hypothetical protein K23787 DMA1_2; E3 ubiquitin-protein ligase DMA1/2 [EC:2.3.2.27]
B Atypical E3
C PGUG_03024 hypothetical protein K22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]
B UBL E3 ligases
C PGUG_02830 hypothetical protein K04706 PIAS1; E3 SUMO-protein ligase PIAS1 [EC:2.3.2.-]
C PGUG_03889 hypothetical protein K22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]
C PGUG_01311 hypothetical protein K17822 DCUN1D1_2; DCN1-like protein 1/2
B Multi subunit Ring-finger type E3
C SCF complex
D Ring finger protein
D Cullin
E PGUG_00569 hypothetical protein K03347 CUL1; cullin 1
D Adaptor protein
E PGUG_03114 hypothetical protein K03094 SKP1; S-phase kinase-associated protein 1
D Target recognizing subunit (F-box)
E PGUG_00537 hypothetical protein K10259 MET30; F-box and WD-40 domain protein MET30
E PGUG_01429 hypothetical protein K03361 CDC4; F-box and WD-40 domain protein CDC4
E PGUG_02169 hypothetical protein K10273 FBXL7; F-box and leucine-rich repeat protein 7
E PGUG_00053 hypothetical protein K10276 FBXL10_11; F-box and leucine-rich repeat protein 10/11 [EC:1.14.11.27]
E PGUG_03078 hypothetical protein K03360 GRR1; F-box and leucine-rich repeat protein GRR1
E PGUG_02616 hypothetical protein K15068 DIA2; protein DIA2
E PGUG_05257 hypothetical protein K10295 FBXO9; F-box protein 9
E PGUG_03406 hypothetical protein K15071 RCY1; recyclin-1
E PGUG_02605 hypothetical protein K15072 SAF1; SCF-associated factor 1
E PGUG_04250 hypothetical protein K15073 UFO1; ubiquitin ligase complex F-box protein UFO1
C Cul2 complex
D Ring finger protein
D Cullin
D Adoptor protein
E PGUG_04799 hypothetical protein K03872 ELOC; elongin-C
D Target recognizing subunit
C Cul3 complex
D Ring finger protein
D Cullin
E PGUG_05868 hypothetical protein K03869 CUL3; cullin 3
D Adoptor and target recognizing subunit (BTB)
E PGUG_00375 hypothetical protein K10520 ABTB1; ankyrin repeat and BTB/POZ domain-containing protein 1
C Cul4 complex
D Ring finger protein
D Cullin
E PGUG_04159 hypothetical protein K10609 CUL4; cullin 4
D Adoptor protein
D Target recognizing subunit (DCAF)
E PGUG_00690 hypothetical protein K10570 ERCC8; DNA excision repair protein ERCC-8
E PGUG_04867 hypothetical protein K11805 DCAF7; DDB1- and CUL4-associated factor 7
E PGUG_03573 hypothetical protein K11806 DCAF13; DDB1- and CUL4-associated factor 13
E PGUG_04773 hypothetical protein K22382 WDR26; WD repeat-containing protein 26
E PGUG_00362 hypothetical protein K24755 WDR76; WD repeat-containing protein 76
C Cul5 complex
D Ring finger protein
D Cullin
D Adoptor protein
E PGUG_04799 hypothetical protein K03872 ELOC; elongin-C
D Target recognizing subunit
C Cul7 complex
D Ring finger protein
D Cullin
D Adaptor protein
E PGUG_03114 hypothetical protein K03094 SKP1; S-phase kinase-associated protein 1
D Target recognizing subunit
C Cul8 complex
D Ring finger protein
D Cullin
D Adaptor protein
D Target recognizing subunit
E PGUG_05871 hypothetical protein K26122 MMS22; E3 ubiquitin-protein ligase substrate receptor MMS22
C Cul9 complex
D Ring finger protein
D Cullin
C APC/C
D Ring finger protein
E PGUG_01115 hypothetical protein K03358 APC11; anaphase-promoting complex subunit 11
D Cullin
E PGUG_01312 hypothetical protein K03349 APC2; anaphase-promoting complex subunit 2
D Target recognizing subunit
E PGUG_05032 hypothetical protein K03363 CDC20; cell division cycle 20, cofactor of APC complex
E PGUG_02077 hypothetical protein K03364 CDH1; cell division cycle 20-like protein 1, cofactor of APC complex
E PGUG_02374 hypothetical protein K12782 AMA1; meiosis-specific APC/C activator protein AMA1
E PGUG_02373 hypothetical protein K12782 AMA1; meiosis-specific APC/C activator protein AMA1
D Other subunits
E PGUG_04730 hypothetical protein K03348 APC1; anaphase-promoting complex subunit 1
E PGUG_00314 hypothetical protein K03350 APC3; anaphase-promoting complex subunit 3
E PGUG_02166 hypothetical protein K03351 APC4; anaphase-promoting complex subunit 4
E PGUG_04167 hypothetical protein K03352 APC5; anaphase-promoting complex subunit 5
E PGUG_05368 hypothetical protein K03353 APC6; anaphase-promoting complex subunit 6
E PGUG_00099 hypothetical protein K03355 APC8; anaphase-promoting complex subunit 8
E PGUG_03128 hypothetical protein K03357 APC10; anaphase-promoting complex subunit 10
C BRCC complex
D PGUG_03869 hypothetical protein K04482 RAD51; DNA repair protein RAD51
C KPC complex
C LUBAC complex
C CTLH complex
D PGUG_04800 hypothetical protein K23333 RMND5; E3 ubiquitin-protein transferase RMND5 [EC:2.3.2.27]
D PGUG_01993 hypothetical protein K18624 MAEA; macrophage erythroblast attacher
D PGUG_04237 hypothetical protein K23335 GID4; glucose-induced degradation protein 4
D PGUG_02220 hypothetical protein K23338 GID8; glucose-induced degradation protein 8
D PGUG_04773 hypothetical protein K22382 WDR26; WD repeat-containing protein 26
C ERAD complex
C LMBR1L-GP78-UBAC2 complex
C SLX5-SLX8 complex
D PGUG_05475 hypothetical protein K22645 SLX5; E3 ubiquitin-protein ligase complex SLX5-SLX8 subunit SLX5 [EC:2.3.2.27]
D PGUG_05103 hypothetical protein K22646 SLX8; E3 ubiquitin-protein ligase complex SLX5-SLX8 subunit SLX8 [EC:2.3.2.27]
C Multi subunit type E3 associated proteins
D PGUG_01419 hypothetical protein K17263 CAND1; cullin-associated NEDD8-dissociated protein 1
D PGUG_03112 hypothetical protein K24350 UBXN7; UBX domain-containing protein 7
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ADeubiquitinating enzyme (DUB)
B Ubiquitin-specific proteases (UBPs)
C UCH
D PGUG_04443 hypothetical protein K05609 UCHL3; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]
D PGUG_03064 hypothetical protein K05610 UCHL5; ubiquitin carboxyl-terminal hydrolase L5 [EC:3.4.19.12]
C UBP/USP
D PGUG_04456 hypothetical protein K11835 USP4_11; ubiquitin carboxyl-terminal hydrolase 4/11 [EC:3.4.19.12]
D PGUG_02717 hypothetical protein K11836 USP5_13; ubiquitin carboxyl-terminal hydrolase 5/13 [EC:3.4.19.12]
D PGUG_03554 hypothetical protein K11838 USP7; ubiquitin carboxyl-terminal hydrolase 7 [EC:3.4.19.12]
D PGUG_00492 hypothetical protein K11839 USP8; ubiquitin carboxyl-terminal hydrolase 8 [EC:3.4.19.12]
D PGUG_01652 hypothetical protein K11841 USP10; ubiquitin carboxyl-terminal hydrolase 10 [EC:3.4.19.12]
D PGUG_02732 hypothetical protein K11843 USP14; ubiquitin carboxyl-terminal hydrolase 14 [EC:3.4.19.12]
D PGUG_03560 hypothetical protein K11366 USP22_27_51; ubiquitin carboxyl-terminal hydrolase 22/27/51 [EC:3.4.19.12]
D PGUG_04777 hypothetical protein K11849 USP25; ubiquitin carboxyl-terminal hydrolase 25 [EC:3.4.19.12]
D PGUG_01995 hypothetical protein K11870 UBP1; ubiquitin carboxyl-terminal hydrolase 1 [EC:3.4.19.12]
D PGUG_00140 hypothetical protein K11871 UBP7_11; ubiquitin carboxyl-terminal hydrolase 7/11 [EC:3.4.19.12]
D PGUG_05202 hypothetical protein K11872 UBP9_13; ubiquitin carboxyl-terminal hydrolase 9/13 [EC:3.4.19.12]
D PGUG_04851 hypothetical protein K11873 UBP10; ubiquitin carboxyl-terminal hydrolase 10 [EC:3.4.19.12]
D PGUG_05588 hypothetical protein K11874 UBP16; ubiquitin carboxyl-terminal hydrolase 16 [EC:3.4.19.12]
C OTU
D PGUG_03374 hypothetical protein K18342 OTUD6; OTU domain-containing protein 6 [EC:3.4.19.12]
C MJD
C MINDY
D PGUG_05133 hypothetical protein K01309 MINDY1_2; ubiquitin carboxyl-terminal hydrolase MINDY-1/2 [EC:3.4.19.12]
C JAMM
D PGUG_01059 hypothetical protein K03030 PSMD14; 26S proteasome regulatory subunit N11
C PPPDE
C ZUFSP
C BRISC complex
B UBL-specific proteases (ULPs)
C PGUG_00285 hypothetical protein K08592 SENP1; sentrin-specific protease 1 [EC:3.4.22.68]
C PGUG_05330 hypothetical protein K08596 SENP7; sentrin-specific protease 7 [EC:3.4.22.68]
C PGUG_01817 hypothetical protein K08597 SENP8; sentrin-specific protease 8 [EC:3.4.22.68]
C PGUG_04443 hypothetical protein K05609 UCHL3; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]
C PGUG_04313 hypothetical protein K22762 DESI1; desumoylating isopeptidase 1 [EC:3.4.-.-]
C COP9 signalosome (CSN) complex
D PGUG_01722 hypothetical protein K12176 COPS2; COP9 signalosome complex subunit 2
D PGUG_04850 hypothetical protein K09613 COPS5; COP9 signalosome complex subunit 5 [EC:3.4.-.-]
D PGUG_03081 hypothetical protein K24364 CSN12; COP9 signalosome complex subunit 12
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: June 3, 2024