+C Peptidases and inhibitors KO
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Peptidases and Inhibitors - Pseudoalteromonas translucida TAC125
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AAspartic peptidases
B Family A1: pepsin family
B Family A2: retropepsin family
B Family A5: thermopsin family
B Family A8: signal peptidase II family
C PSHAa0919 lspA; lipoprotein signal peptidase (SPase II)(Prolipoprotein signal peptidase) K03101 lspA; signal peptidase II [EC:3.4.23.36]
B Family A22: presenilin family
B Family A24: type IV prepilin peptidase family
C PSHAa0380 pilD; Type 4 prepilin-like proteins leader peptide processing enzyme K02654 pilD; leader peptidase (prepilin peptidase) / N-methyltransferase [EC:3.4.23.43 2.1.1.-]
B Family A25: gpr protease family
B Family A26: omptin family
B Family A28
B Family A31: HybD endopeptidase family
B Family A36
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ACysteine peptidases
B Family C1: papain family
B Family C2: calpain family
B Family C3: picornain family
B Family C4: NIa protease family
B Family C5
B Family C9
B Family C10: streptopain family
B Family C11: clostripain family
B Family C12: ubiquitin C-terminal hydrolase family
B Family C13: legumain family
B Family C14: caspase family
B Family C15: pyroglutamyl peptidase I family
C PSHAa1441 Pyrrolidone-carboxylate peptidase (EC 3.4.19.3) (5-oxoprolyl-peptidase) (Pyroglutamyl-peptidase I) (PGP-I) (Pyrase) K01304 pcp; pyroglutamyl-peptidase [EC:3.4.19.3]
B Family C16
B Family C19: ubiquitin-specific protease family
B Family C25: gingipain family
B Family C26: gamma-glutamyl hydrolase family
C PSHAa0649 guaA; GMP synthetase (glutamine aminotransferase) K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
B Family C27
B Family C30
B Family C37
B Family C39
B Family C40
B Family C44
C PSHAa2070 purF; amidophosphoribosyltransferase (PRPP amidotransferase) K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
C PSHAb0127 gltB; glutamate synthase, large subunit, GOGAT K00265 gltB; glutamate synthase (NADPH) large chain [EC:1.4.1.13]
C PSHAa2994 glmS; L-glutamine:D-fructose-6-phosphate aminotransferase K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
C PSHAa1440 asnB; asparagine synthetase B[glutamine-hydrolyzing] K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]
B Family C45
B Family C46: hedgehog family
B Family C47: staphopain family
B Family C48: Ulp1 endopeptidase family
B Family C50: separase family
B Family C54: Aut2 peptidase family
B Family C55: YopJ protease family
B Family C56: PfpI endopeptidase family
B Family C57: vaccinia virus I7 peptidase family
B Family C58
B Family C59
B Family C60
C PSHAa0631 putative transpeptidase family protein K07284 srtA; sortase A [EC:3.4.22.70]
B Family C63
B Family C64
B Family C65
B Family C67
B Family C69
B Family C70
B Family C75
B Family C76
B Family C78
B Family C79
B Family C82
B Family C83
B Family C85
B Family C86
B Family C88
B Family C89
B Family C97
B Family C98
B Family C110
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AGlutamic peptidases
B Family G1
B Family G4
B Family G5: prenyl protease 2 family
C PSHAa0639 conserved protein of unknown function K07052 K07052; CAAX protease family protein
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AMetallo peptidases
B Family M1
C PSHAa2915 putative cold-active aminopeptidase; secreted using a signal peptide K01254 LTA4H; leukotriene-A4 hydrolase [EC:3.3.2.6]
C PSHAa1676 pepN; aminopeptidase N, a cysteinylglycinase K01256 pepN; aminopeptidase N [EC:3.4.11.2]
B Family M2
B Family M3
C PSHAa0361 prlC; oligopeptidase A K01414 prlC; oligopeptidase A [EC:3.4.24.70]
C PSHAa2184 dcp; Peptidyl-dipeptidase dcp (Dipeptidyl carboxypeptidase) K01284 dcp; peptidyl-dipeptidase Dcp [EC:3.4.15.5]
B Family M4: thermolysin family
B Family M5: mycolysin family
B Family M6: immune inhibitor A family
B Family M7: snapalysin family
B Family M8: leishmanolysin family
B Family M9
B Family M10
B Family M12: astacin/adamalysin family
B Family M13: neprilysin family
C PSHAa1371 putative peptidase M13 family protein K07386 pepO; putative endopeptidase [EC:3.4.24.-]
C PSHAa2745 Peptidase, M13 family (lipoprotein) K07386 pepO; putative endopeptidase [EC:3.4.24.-]
B Family M14: carboxypeptidase A family
B Family M15: zinc D-Ala-D-Ala carboxypeptidase family
B Family M16: pitrilysin family
C PSHAb0349 putative TonB-dependent receptor protease/peptidase K01407 ptrA; protease III [EC:3.4.24.55]
C PSHAa0972 putative peptidase K01408 IDE; insulysin [EC:3.4.24.56]
C PSHAa1089 putative peptidase K07263 pqqL; zinc protease [EC:3.4.24.-]
C PSHAa0643 conserved protein of unknown function K07263 pqqL; zinc protease [EC:3.4.24.-]
B Family M17: leucyl aminopeptidase family
C PSHAb0302 putative aminopeptidase K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1]
C PSHAa2388 putative cytosol aminopeptidase K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1]
C PSHAa2423 pepA; cytosol aminopeptidase (Leucine aminopeptidase, Leucyl aminopeptidase) K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1]
C PSHAa1484 putative cytosol aminopeptidase 1 (EC 3.4.11.1) (Leucine aminopeptidase 1) (LAP 1) (Leucyl aminopeptidase 1) K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1]
C PSHAa0608 pepB; aminopeptidase B, a cysteinylglycinase K07751 pepB; PepB aminopeptidase [EC:3.4.11.23]
B Family M18
B Family M19: membrane dipeptidase family
C PSHAa2910 putative periplasmic dipeptidase K01273 DPEP; membrane dipeptidase [EC:3.4.13.19]
B Family M20
C PSHAb0171 putative hydrolase K01295 cpg; glutamate carboxypeptidase [EC:3.4.17.11]
C PSHAa1331 dapE; Succinyl-diaminopimelate desuccinylase (SDAP) K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18]
C PSHAa2204 putative hydrolase K01270 pepD; dipeptidase D [EC:3.4.13.-]
B Family M23
B Family M24
C PSHAa2037 map; methionine aminopeptidase; contains a divalent metal, usually cobalt K01265 map; methionyl aminopeptidase [EC:3.4.11.18]
C PSHAa0013 pepQ; Xaa-Pro proline dipeptidase K01271 pepQ; Xaa-Pro dipeptidase [EC:3.4.13.9]
C PSHAa0562 pepP; proline aminopeptidase P II K01262 pepP; Xaa-Pro aminopeptidase [EC:3.4.11.9]
B Family M26
B Family M27
B Family M28: aminopeptidase Y family
B Family M29: aminopeptidase T family
B Family M32: carboxypeptidase Taq family
B Family M34: anthrax lethal factor family
B Family M35: deuterolysin family
B Family M36: fungalysin family
B Family M38: beta-aspartyl dipeptidase family
B Family M41: FtsH endopeptidase family
C PSHAa0870 ftsH; cell division protease ftsH, ATP-dependent zinc-metallo protease K03798 ftsH; cell division protease FtsH [EC:3.4.24.-]
B Family M42: glutamyl aminopeptidase family
B Family M43: cytophagalysin family
B Family M44
B Family M48: Ste24 endopeptidase family
C PSHAa1605 htpX; zinc metalloprotease HtpX, membrane-bound with cytosolic active site; heat shock protein K03799 htpX; heat shock protein HtpX [EC:3.4.24.-]
C PSHAa1134 putative prenylyltransferase domain and metalloproteases (zincins), catalytic domain K01423 bepA; beta-barrel assembly-enhancing protease [EC:3.4.-.-]
B Family M49: dipeptidyl-peptidase III family
B Family M50: S2P protease family
C PSHAa2029 ecfE; membrane-associated protease K11749 rseP; regulator of sigma E protease [EC:3.4.24.-]
B Family M54
B Family M55: DppA aminopeptidase family
B Family M56
B Family M67
B Family M72
B Family M73
B Family M74
B Family M80
B Family M82
B Family M85
B Family M88
B Family M90
C PSHAa1170 conserved protein of unknown function K09933 mtfA; MtfA peptidase
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AAsparagine peptide lyases
B Family N1
B Family N8
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AMixed peptidases
B Family P1: DmpA aminopeptidase family
B Family P2
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ASerine peptidases
B Family S1: chymotrypsin family
C PSHAa2536 degQ; periplasmic serine endoprotease K04772 degQ; serine protease DegQ [EC:3.4.21.-]
C PSHAa2537 degS; periplasmic serine endoprotease K04691 hhoB; serine protease DegS [EC:3.4.21.-]
B Family S3: togavirin family
B Family S6
B Family S7: flavivirin family
B Family S8: subtilisin family
C PSHAa2649 Serine protease precursor K14645 K14645; serine protease [EC:3.4.21.-]
B Family S9: prolyl oligopeptidase family
C PSHAa1273 Prolyl endopeptidase K01322 PREP; prolyl oligopeptidase [EC:3.4.21.26]
C PSHAb0005 Dipeptidyl-peptidase IV K01278 DPP4; dipeptidyl-peptidase 4 [EC:3.4.14.5]
C PSHAa2386 Dipeptidyl peptidase IV K01278 DPP4; dipeptidyl-peptidase 4 [EC:3.4.14.5]
C PSHAa2955 ptrB; oligopeptidase, type B K01354 ptrB; oligopeptidase B [EC:3.4.21.83]
C PSHAa0069 ptrB; oligopeptidase (protease II) K01354 ptrB; oligopeptidase B [EC:3.4.21.83]
B Family S10
B Family S11: D-Ala-D-Ala carboxypeptidase A family
C PSHAa1022 dacA; D-alanyl-D-alanine carboxypeptidase, penicillin-binding protein 5 K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4]
B Family S12: D-Ala-D-Ala carboxypeptidase B family
C PSHAa0522 conserved protein of unknown function; putative peptidase with beta-lactamase domain (partial match) K21469 pbp4b; serine-type D-Ala-D-Ala carboxypeptidase [EC:3.4.16.4]
B Family S13: D-Ala-D-Ala peptidase C family
B Family S14: ClpP endopeptidase family
C PSHAa2062 clpP; ATP-dependent Clp protease proteolytic subunit (Endopeptidase Clp) (Caseinolytic protease) (Protease Ti)(Heat shock protein F21.5) K01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92]
B Family S15
B Family S16: lon protease family
C PSHAa2060 lon; DNA-binding ATP-dependent protease La; heat shock K-protein K01338 lon; ATP-dependent Lon protease [EC:3.4.21.53]
B Family S21: assemblin family
B Family S24: LexA family
C PSHAa2873 lexA; transcriptional repressor for SOS response K01356 lexA; repressor LexA [EC:3.4.21.88]
C PSHAb0537 umuD; component of DNA polymerase V K03503 umuD; DNA polymerase V [EC:3.4.21.-]
B Family S26: signal peptidase I family
C PSHAa1310 putative signal peptidase I family protein K03100 lepB; signal peptidase I [EC:3.4.21.89]
C PSHAa0731 lepB; signal peptidase I (SPase I) (Leader peptidase I) K03100 lepB; signal peptidase I [EC:3.4.21.89]
B Family S28
B Family S31
B Family S32
B Family S33
B Family S41: C-terminal processing peptidase family
C PSHAa0364 putative carboxyl-terminal protease K03797 E3.4.21.102; carboxyl-terminal processing protease [EC:3.4.21.102]
C PSHAa1678 prc; periplasmic carboxy-terminal protease with specificity for non-polar C-termini K03797 E3.4.21.102; carboxyl-terminal processing protease [EC:3.4.21.102]
C PSHAa1038 putative protease K08676 tri; tricorn protease [EC:3.4.21.-]
B Family S45
C PSHAa0079 putative hydrolase K01434 pac; penicillin G amidase [EC:3.5.1.11]
B Family S49: protease IV family
C PSHAa1409 sppA; protease IV, a signal peptide peptidase K04773 sppA; protease IV [EC:3.4.21.-]
C PSHAa1345 sohB; protease (may metabolize cleaved signal peptides) K04774 sohB; serine protease SohB [EC:3.4.21.-]
B Family S50
B Family S51
B Family S53
B Family S54: Rhomboid family
C PSHAa2313 putative GlpG protein K02441 glpG; rhomboid protease GlpG [EC:3.4.21.105]
B Family S55: SpoIVB peptidase family
B Family S62
B Family S66
C PSHAa1232 conserved protein of unknown function K01297 ldcA; muramoyltetrapeptide carboxypeptidase [EC:3.4.17.13]
B Family S77: phage prohead processing peptidase family
B Family S78
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AThreonine peptidases
B Family T1: proteasome family
C PSHAa2730 hslV; peptidase component of the HslUV protease K01419 hslV; ATP-dependent HslUV protease, peptidase subunit HslV [EC:3.4.25.2]
B Family T2
C PSHAa1143 iaaA; L-asparaginase K13051 ASRGL1; L-asparaginase / beta-aspartyl-peptidase [EC:3.5.1.1 3.4.19.5]
B Family T3: gamma-glutamyltransferase family
C PSHAa1566 putative gamma-glutamyltranspeptidase K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
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APeptidases of unknown catalytic type
B Family U32
C PSHAb0145 yegQ; putative peptidase YegQ K08303 prtC; U32 family peptidase [EC:3.4.-.-]
B Family U62
C PSHAa2747 pmbA; putative enzyme for maturation of Microcin B17 and degradation of CcdA K03592 pmbA; PmbA protein
C PSHAa2675 tldD; putative suppressor of CsrA inhibitory activity; putative peptidase; involved in the control of DNA gyrase K03568 tldD; TldD protein
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APeptidase inhibitors
B Family I1: Kazal family
B Family I2: Kunitz - BPTI family
B Family I4: serpin family
B Family I11: ecotin family
B Family I17: WAP-type family
B Family I25: cystatin family
B Family I27: calpastatin family
B Family I32: IAP family
B Family I34: IA3 family
B Family I35: timp family
B Family I39: alpha2M family
B Family I47: latexin family
B Family I49: proSAAS family
B Family I51: IC family
B Family I57: staphostatin B family
B Family I63
B Family I80
B Family I87
C PSHAa0274 hflC; HflC; HflKC is a membrane-associated complex K04087 hflC; modulator of FtsH protease HflC
C PSHAa0273 hflK; HflK complex with HflC K04088 hflK; modulator of FtsH protease HflK
B Family I93
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: May 29, 2024
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Classification taken and modified from MEROPS