+D	Messenger RNA Biogenesis	KO
#<h2><a href="/kegg/brite.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; Prokaryotic Defense System - Paenibacillus polymyxa E681</h2>
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A<b>CRISPR-Cas system</b>
B  Universal Cas proteins
B  Type I CRISPR-Cas system
C    Type I signiture cas proteins
C    Subtype I-A factors
C    Subtype I-B factors
C    Subtype I-C factors
C    Subtype I-D factors
C    Subtype I-E factors
C    Subtype I-F factors
C    Subtype I-U factors
B  Type II CRISPR-Cas system
C    Type II signiture cas proteins
C    Subtype II-A factors
C    Subtype II-B factors
B  Type III CRISPR-Cas system
C    Type III signiture cas proteins
C    Subtype III-A factors
C    Subtype III-B factors
C    Subtype III-U factors
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A<b>Restriction and modification system (R-M system)</b>
B  Type I R-M system
B  Type II R-M system
C    Restriction endonucleases
C    DNA methyltransferases
D      PPE_03048 DNA methyltransferase	K06223 dam; DNA adenine methylase [EC:2.1.1.72] 
D      PPE_03026 hypothetical protein	K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] 
D      PPE_04693 DNA methyltransferase	K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] 
B  Type III R-M system
C    PPE_00816 adenine methyltransferase	K07316 mod; adenine-specific DNA-methyltransferase [EC:2.1.1.72] 
B  Type IV R-M system
C    PPE_01058 hypothetical protein	K07448 mrr; restriction system protein 
C    PPE_03294 endonuclease	K07448 mrr; restriction system protein 
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A<b>Toxin-antitoxin system (TA system)</b>
B  Type I TA system
C    Hok-Sok
C    SymE-SymR
C    Ldr-Rdl
C    TisB-IstR
C    Ibs-Sib
C    ShoB-OhsC
C    RalR-RalA
B  Type II TA system
C    MazF-MazE
D      PPE_01221 PemK family transcriptional regulator	K07171 mazF; mRNA interferase MazF [EC:3.1.-.-] 
D      PPE_00228 AbrB family transcriptional regulator	K07172 mazE; antitoxin MazE 
D      PPE_01220 antitoxin	K07723 ndoAI; CopG family transcriptional regulator / antitoxin EndoAI 
C    ChpB-ChpS
C    YhaV-PrlF
C    RelE/StbE-RelB/StbD
C    YafQ-dinJ
C    YoeB-YefM
C    HipA-HipB
C    HicA-HicB
C    YafO-YafN
C    Hha-TomB
C    PspC-PspB
D      PPE_03968 stress-responsive transcriptional regulator	K03973 pspC; phage shock protein C 
C    CcdB-CcdA
C    ParE-ParD
C    Doc-Phd
D      PPE_00227 phage killer protein	K07341 doc; death on curing protein 
C    HigB-HigA
C    MqsR-MqsA
C    VapC-VapB
C    PezT-PezA
C    YobL-YobK
C    YokI-YokJ
C    YqcG-YqcF
C    YxiD-YxxD
C    FitB-FitA
C    BC_0920-BC_0921
C    Type II TA system related factors
D      PPE_03122 cell division protein FtsZ	K03531 ftsZ; cell division protein FtsZ 
D      PPE_04447 rod shape-determining protein Mbl	K03569 mreB; rod shape-determining protein MreB and related proteins 
D      PPE_03666 rod shape-determining protein Mbl	K03569 mreB; rod shape-determining protein MreB and related proteins 
D      PPE_02640 DNA topoisomerase IV subunit A	K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2] 
D      PPE_02641 DNA topoisomerase IV subunit B	K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2] 
D      PPE_02012 glutamyl-Q tRNA(Asp) ligase	K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] 
B  Type III TA system
C    AbiQ system
B  Type IV TA system
C    YeeV-YeeU
C    CptA-CptB
B  Type V TA system
C    GhoT-GhoS
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A<b>DNA phosphothiolation system</b>
B  Sulfur modification proteins
C    PPE_02187 cysteine desulfarase	K04487 iscS; cysteine desulfurase [EC:2.8.1.7] 
C    PPE_03156 aminotransferase V	K04487 iscS; cysteine desulfurase [EC:2.8.1.7] 
C    PPE_03582 cysteine desulfurase	K04487 iscS; cysteine desulfurase [EC:2.8.1.7] 
B  DNA phosphorothioation-dependent restriction proteins
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#Last updated: November 7, 2023