+F Repair protein KO
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DNA Repair and Recombination Proteins - Salmonella enterica subsp. enterica serovar Paratyphi A AKU12601
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D SSPA1137 O6-methylguanine-DNA-alkyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D SSPA1893 deoxyribodipyrimidine photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E SSPA0256 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E SSPA2772 A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E SSPA1300 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D SSPA0135 7,8-dihydro-8-oxoguanine-triphosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SSPA3346 deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D SSPA1137 O6-methylguanine-DNA-alkyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D SSPA0563 ADA regulatory protein K10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response / methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]
D SSPA1893 deoxyribodipyrimidine photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D SSPA0564 AlkB protein K03919 alkB; DNA oxidative demethylase [EC:1.14.11.33]
C BER (base exicision repair)
D DNA glycosylases
E SSPA0256 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E SSPA2877 G/U mismatch-specific DNA glycosylase K03649 mug; double-stranded uracil-DNA glycosylase [EC:3.2.2.28]
E SSPA0699 DNA-3-methyladenine glycosidase II K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E SSPA2772 A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E SSPA3261 3-methyladenine DNA glycosylase I, constitutive K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E SSPA3341 formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E SSPA1877 endonuclease VIII, DNA N-glycosylase with an AP lyase activity K05522 nei; endonuclease VIII [EC:3.2.2.- 4.2.99.18]
E SSPA1300 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E SSPA1433 exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E SSPA0609 endonuclease IV K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
E SSPA3720 putative endonuclease K05982 E3.1.21.7; deoxyribonuclease V [EC:3.1.21.7]
D RecJ
E SSPA2712 single-stranded DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E SSPA3354 putative DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E SSPA0411 DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E SSPA3571 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E SSPA3780 excision nuclease subunit A K03701 uvrA; excinuclease ABC subunit A
E SSPA1822 excision nuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
E SSPA0861 excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C
E SSPA1426 conserved hypothetical protein K05984 cho; excinuclease Cho [EC:3.1.25.-]
E SSPA3530 DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E SSPA3571 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E SSPA3354 putative DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E SSPA0411 DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F SSPA3706 DNA-directed RNA polymerase, beta-subunit K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F SSPA3707 DNA-directed RNA polymerase, beta'-subunit K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F SSPA3060 DNA-directed RNA polymerase alpha chain K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F SSPA3356 DNA-directed RNA polymerase omega chain K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F SSPA1519 transcription-repair coupling factor (TrcF) K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E SSPA2578 DNA mismatch repair protein K03555 mutS; DNA mismatch repair protein MutS
D Molecular matchmaker
E SSPA3876 DNA mismatch repair protein K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
E SSPA2675 DNA mismatch repair protein K03573 mutH; DNA mismatch repair protein MutH
D DNA exonucleases
E SSPA0754 exodeoxyribonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
E SSPA0332 exodeoxyribonuclease large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E SSPA2141 exodeoxyribonuclease small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
E SSPA0924 exodeoxyribonuclease X K10857 exoX; exodeoxyribonuclease X [EC:3.1.11.-]
D DNA polymerase III holoenzyme
E SSPA0230 DNA polymerase III, alpha chain K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E SSPA3436 DNA polymerase III beta-subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E SSPA3974 DNA polymerase III, chi subunit K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
E SSPA1940 DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E SSPA1534 DNA polymerase III, delta' subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E SSPA2336 DNA polymerase III epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E SSPA2081 DNA polymerase III subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
E SSPA4057 DNA polymerase III, psi subunit K02344 holD; DNA polymerase III subunit psi [EC:2.7.7.7]
E SSPA0926 DNA polymerase III, theta subunit K02345 holE; DNA polymerase III subunit theta [EC:2.7.7.7]
D DNA ligase
E SSPA3354 putative DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E SSPA0411 DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E SSPA3530 DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E SSPA3781 single-strand DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E SSPA2414 DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
E SSPA2445 putative phage gene K06223 dam; DNA adenine methylase [EC:2.1.1.72]
E SSPA3125 DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
E SSPA0819 patch repair protein K07458 vsr; DNA mismatch endonuclease, patch repair protein [EC:3.1.-.-]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E SSPA2662 exonuclease V subunit K03582 recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5]
E SSPA2664 exonuclease V subunit K03583 recC; exodeoxyribonuclease V gamma subunit [EC:3.1.11.5]
E SSPA2661 exonuclease V alpha-subunit K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E SSPA2501 RecA protein K03553 recA; recombination protein RecA
E SSPA0908 Holliday junction DNA helicase K03550 ruvA; holliday junction DNA helicase RuvA
E SSPA0909 Holliday junction DNA helicase K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E SSPA0905 crossover junction endodeoxyribonuclease K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E SSPA2240 hypothetical protein K01160 rusA; crossover junction endodeoxyribonuclease RusA [EC:3.1.21.10]
E SSPA3665 primosomal protein replication factor K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E SSPA3909 primosomal replication protein N K02686 priB; primosomal replication protein N
E SSPA2084 primosomal replication protein N K04067 priC; primosomal replication protein N''
E SSPA4047 primosomal protein I K02317 dnaT; DNA replication protein DnaT
E SSPA0754 exodeoxyribonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
E SSPA2171 exonuclease SbcC K03546 sbcC; DNA repair protein SbcC/Rad50
E SSPA2170 exonuclease SbcD K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E SSPA2501 RecA protein K03553 recA; recombination protein RecA
E SSPA4074 putative DNA repair protein K04485 radA; DNA repair protein RadA/Sms
E SSPA3435 recF protein K03629 recF; DNA replication and repair protein RecF
E SSPA3359 ATP-dependent DNA helicase K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E SSPA2712 single-stranded DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E SSPA0271 DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E SSPA2079 recombination protein RecR K06187 recR; recombination protein RecR
E SSPA2368 DNA repair protein K03631 recN; DNA repair protein RecN (Recombination protein N)
E SSPA2174 recombination associated protein RdgC K03554 rdgC; recombination associated protein RdgC
E SSPA0908 Holliday junction DNA helicase K03550 ruvA; holliday junction DNA helicase RuvA
E SSPA0909 Holliday junction DNA helicase K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E SSPA0905 crossover junction endodeoxyribonuclease K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
D Other HR factor
E SSPA2605 conserved hypothetical protein K15342 cas1; CRISP-associated protein Cas1
E SSPA0588 putative helicase K19789 radD; DNA repair protein RadD
D Archaeal homologous recombinant proteins
E SSPA2171 exonuclease SbcC K03546 sbcC; DNA repair protein SbcC/Rad50
E SSPA2170 exonuclease SbcD K03547 sbcD; DNA repair protein SbcD/Mre11
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F SSPA0557 DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F SSPA3434 DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F SSPA1081 DNA topoisomerase I, omega protein I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F SSPA3722 histone like DNA-binding protein HU-alpha (NS2) (HU-2) K05787 hupA; DNA-binding protein HU-alpha
F SSPA2113 DNA-binding protein HU-beta K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F SSPA2712 single-stranded DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F SSPA0271 DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F SSPA2079 recombination protein RecR K06187 recR; recombination protein RecR
F SSPA3354 putative DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
F SSPA0411 DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
F SSPA3038 Fis DNA-binding protein K03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein
F SSPA1396 integration host factor alpha-subunit K04764 ihfA; integration host factor subunit alpha
F SSPA1688 integration host factor beta-subunit (IHF-beta) K05788 ihfB; integration host factor subunit beta
E Supressor
F SSPA0754 exodeoxyribonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
F SSPA3537 ATP-dependent DNA helicase K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F SSPA3780 excision nuclease subunit A K03701 uvrA; excinuclease ABC subunit A
F SSPA1822 excision nuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
F SSPA1046 DNA-binding protein (histone-like protein Hlp-II) K03746 hns; DNA-binding protein H-NS
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D SSPA2280 hypothetical protein DinP (DNA damage-inducible protein) K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D SSPA0813 UmuC protein K03502 umuC; DNA polymerase V
D SSPA0812 UmuD protein K03503 umuD; DNA polymerase V [EC:3.4.21.-]
C Other SOS response factors
D SSPA2501 RecA protein K03553 recA; recombination protein RecA
D SSPA3763 LexA repressor K01356 lexA; repressor LexA [EC:3.4.21.88]
D SSPA2368 DNA repair protein K03631 recN; DNA repair protein RecN (Recombination protein N)
D SSPA0094 DNA polymerase II K02336 polB; DNA polymerase II [EC:2.7.7.7]
D SSPA3781 single-strand DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D SSPA1570 damage-inducible protein K12149 dinI; DNA-damage-inducible protein I
D SSPA2411 hypothetical protein K12149 dinI; DNA-damage-inducible protein I
D SSPA2500 putative regulatory protein RecX K03565 recX; regulatory protein
D SSPA3148 conserved hypothetical protein K24087 rpnB; recombination-promoting nuclease RpnB [EC:3.1.21.-]
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D SSPA3498 ATP-dependent DNA helicase K03656 rep; ATP-dependent DNA helicase Rep [EC:5.6.2.4]
D SSPA1648 helicase IV (75 kD helicase) K03658 helD; DNA helicase IV [EC:5.6.2.4]
D SSPA1801 LexA regulated (SOS) repair enzyme K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
D SSPA0982 putative ATP-dependent helicase K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
C Modulation of nucleotide pools
D SSPA0135 7,8-dihydro-8-oxoguanine-triphosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SSPA3346 deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D SSPA2486 ribonucleoside-diphosphate reductase 2 alpha chain K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D SSPA0552 ribonucleoside-diphosphate reductase 1 alpha chain K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D SSPA0551 ribonucleoside-diphosphate reductase 1 beta chain K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024