+D GENES KO #

  KEGG Orthology (KO) - Streptococcus pneumoniae R6 (avirulent serotype 2)

% ! A09100 Metabolism B B 09101 Carbohydrate metabolism C 00010 Glycolysis / Gluconeogenesis [PATH:spr00010] D spr0584 glcK; Glucose kinase K25026 glk; glucokinase [EC:2.7.1.2] D spr1882 gpi; Glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9] D spr0796 pfkA; 6-phosphofructokinase I K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] D spr0530 fba; Fructose-bisphosphate aldolase K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13] D spr1432 tpi; Triose phosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] D spr1825 gapA; Glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] D spr0441 pgk; Phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3] D spr1499 gpmA; Phosphoglyceromutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] D spr1036 eno; Enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D spr0797 pykF; Pyruvate kinase I; fructose-stimulated K00873 PK; pyruvate kinase [EC:2.7.1.40] D spr1051 acoA; TPP-dependent acetoin dehydrogenase alpha chain K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1] D spr1050 acoB; TPP-dependent acetoin dehydrogenase beta chain K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1] D spr1049 acoC; Dihydrolipoamide S-acetyltransferase K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12] D spr1048 acoL; Dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D spr1100 ldh; L-lactate dehydrogenase K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27] D spr1837 adhE; Alcohol-acetaldehyde dehydrogenase K04072 adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1] D spr0262 adhP; Alcohol dehydrogenase, propanol-preferring K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1] D spr0065 galM; Aldose-1-epimerase (mutarotase) K01785 galM; aldose 1-epimerase [EC:5.1.3.3] D spr1351 pgm; Phosphoglucomutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2] D spr1028 gapN; NADP-dependent glyceraldehyde-3-phosphate dehydrogenase K00131 gapN; glyceraldehyde-3-phosphate dehydrogenase (NADP+) [EC:1.2.1.9] D spr0276 bglA; 6-phospho-beta-glucosidase K01223 E3.2.1.86B; 6-phospho-beta-glucosidase [EC:3.2.1.86] D spr0506 bglH; 6-phospho-beta-glucosidase K01223 E3.2.1.86B; 6-phospho-beta-glucosidase [EC:3.2.1.86] D spr0244 bglA; 6-phospho-beta-glucosidase K01223 E3.2.1.86B; 6-phospho-beta-glucosidase [EC:3.2.1.86] D spr1528 PTS-EII; Phosphotransferase system sugar-specific EII component K02779 ptsG; glucose PTS system EIICB or EIICBA component [EC:2.7.1.199] C 00020 Citrate cycle (TCA cycle) [PATH:spr00020] D spr1048 acoL; Dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D spr1051 acoA; TPP-dependent acetoin dehydrogenase alpha chain K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1] D spr1050 acoB; TPP-dependent acetoin dehydrogenase beta chain K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1] D spr1049 acoC; Dihydrolipoamide S-acetyltransferase K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12] C 00030 Pentose phosphate pathway [PATH:spr00030] D spr1882 gpi; Glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9] D spr1122 zwf; Glucose-6-phosphate 1-dehydrogenase K00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363] D spr1358 Conserved hypothetical protein K07404 pgl; 6-phosphogluconolactonase [EC:3.1.1.31] D spr0335 gnd; 6-phosphogluconate dehydrogenase K00033 PGD; 6-phosphogluconate dehydrogenase [EC:1.1.1.44 1.1.1.343] D spr1797 rpe; Pentose-5-phosphate-3-epimerase K01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1] D spr1841 tktA; Transketolase K00615 E2.2.1.1; transketolase [EC:2.2.1.1] D spr1936 tktC; Putative transketolase c-terminal section K00615 E2.2.1.1; transketolase [EC:2.2.1.1] D spr1937 tktN; Putative transketolase n-terminal section K00615 E2.2.1.1; transketolase [EC:2.2.1.1] D spr0731 rpiA; Ribose-5-phosphate epimerase K01807 rpiA; ribose 5-phosphate isomerase A [EC:5.3.1.6] D spr0745 deoC; Deoxyribose-phosphate aldolase K01619 deoC; deoxyribose-phosphate aldolase [EC:4.1.2.4] D spr0732 deoB; phosphodeoxyribomutase K01839 deoB; phosphopentomutase [EC:5.4.2.7] D spr1351 pgm; Phosphoglucomutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2] D spr0028 prsA; Phosphoribosylpyrophosphate synthase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1] D spr1002 prs; Ribose-phosphate pyrophosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1] D spr0287 kdgA; 2-keto-3-deoxy-6-phosphogluconate aldolase K01625 eda; 2-dehydro-3-deoxyphosphogluconate aldolase / (4S)-4-hydroxy-2-oxoglutarate aldolase [EC:4.1.2.14 4.1.3.42] D spr1028 gapN; NADP-dependent glyceraldehyde-3-phosphate dehydrogenase K00131 gapN; glyceraldehyde-3-phosphate dehydrogenase (NADP+) [EC:1.2.1.9] D spr0288 kdgK; 2-keto-3-deoxygluconate kinase K00874 kdgK; 2-dehydro-3-deoxygluconokinase [EC:2.7.1.45] D spr0530 fba; Fructose-bisphosphate aldolase K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13] D spr0796 pfkA; 6-phosphofructokinase I K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] C 00040 Pentose and glucuronate interconversions [PATH:spr00040] D spr0318 cps2K; The type 2 capsule locus of Streptococcus pneumoniae K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22] D spr0139 ugd; UDP-glucose dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22] D spr1903 galU; UTP-glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D spr1846 sgh; Hexulose-6-phosphate synthase (HumpS) K03078 ulaD; 3-dehydro-L-gulonate-6-phosphate decarboxylase [EC:4.1.1.85] D spr1845 sga; Hexulose-6-phosphate isomerase K03079 ulaE; L-ribulose-5-phosphate 3-epimerase [EC:5.1.3.22] D spr1844 araD; L-ribulose 5-phosphate 4-epimerase K03077 araD; L-ribulose-5-phosphate 4-epimerase [EC:5.1.3.4] D spr1797 rpe; Pentose-5-phosphate-3-epimerase K01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1] D spr1973 fcsK; Fucose kinase K00848 rhaB; rhamnulokinase [EC:2.7.1.5] D spr1148 Conserved hypothetical protein K05352 tarJ; ribitol-5-phosphate 2-dehydrogenase (NADP+) [EC:1.1.1.405] D spr1149 Conserved hypothetical protein K21030 tarI; D-ribitol-5-phosphate cytidylyltransferase [EC:2.7.7.40] D spr1964 fucI; L-fucose isomerase K01818 fucI; L-fucose/D-arabinose isomerase [EC:5.3.1.25 5.3.1.3] D spr1972 fucA; L-fuculose phosphate aldolase K01628 fucA; L-fuculose-phosphate aldolase [EC:4.1.2.17] C 00051 Fructose and mannose metabolism [PATH:spr00051] D spr1565 scrK; Fructokinase K00847 E2.7.1.4; fructokinase [EC:2.7.1.4] D spr0647 pmi; Mannose-6-phosphate isomerase K01809 manA; mannose-6-phosphate isomerase [EC:5.3.1.8] D spr1964 fucI; L-fucose isomerase K01818 fucI; L-fucose/D-arabinose isomerase [EC:5.3.1.25 5.3.1.3] D spr1972 fucA; L-fuculose phosphate aldolase K01628 fucA; L-fuculose-phosphate aldolase [EC:4.1.2.17] D spr1973 fcsK; Fucose kinase K00848 rhaB; rhamnulokinase [EC:2.7.1.5] D spr0796 pfkA; 6-phosphofructokinase I K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] D spr0359 mtlD; Mannitol-1-phosphate 5-dehydrogenase K00009 mtlD; mannitol-1-phosphate 5-dehydrogenase [EC:1.1.1.17] D spr0779 fruB; Fructose-1-phosphate kinase K00882 fruK; 1-phosphofructokinase [EC:2.7.1.56] D spr0530 fba; Fructose-bisphosphate aldolase K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13] D spr1432 tpi; Triose phosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] D spr0780 fruA; Fructose specific-phosphotransferase system IIBC component K02770 fruA; fructose PTS system EIIBC or EIIC component [EC:2.7.1.202] D spr0063 PTS-EII; Phosphotransferase system sugar-specific EII component K02793 manXa; mannose PTS system EIIA component [EC:2.7.1.191] D spr1970 PTS-EII; Phosphotransferase system sugar-specific EII component K02793 manXa; mannose PTS system EIIA component [EC:2.7.1.191] D spr0261 manL; Phosphotransferase system, mannose-specific EIIAB K02794 manX; mannose PTS system EIIAB component [EC:2.7.1.191] D spr0061 PTS-EIIC; Phosphotransferase system sugar-specific EIIC component K02795 manY; mannose PTS system EIIC component D spr0260 manM; Phosphotransferase system, mannose-specific EIIC K02795 manY; mannose PTS system EIIC component D spr1968 PTS-EII; Phosphotransferase system sugar-specific EII component K02795 manY; mannose PTS system EIIC component D spr0062 PTS-EIID; Phosphotransferase system sugar-specific EIID component K02796 manZ; mannose PTS system EIID component D spr0259 manN; Phosphotransferase system, mannose-specific EIID K02796 manZ; mannose PTS system EIID component D spr1967 PTS-EII; Phosphotransferase system sugar-specific EII component K02796 manZ; mannose PTS system EIID component D spr0358 mtlF; Mannitol-specific enzyme IIA component K02798 cmtB; mannitol PTS system EIIA component [EC:2.7.1.197] D spr0356 mtlA; Mannitol PTS EII K02800 mtlA; mannitol PTS system EIICBA or EIICB component [EC:2.7.1.197] C 00052 Galactose metabolism [PATH:spr00052] D spr0065 galM; Aldose-1-epimerase (mutarotase) K01785 galM; aldose 1-epimerase [EC:5.1.3.3] D spr1668 galK; Galactokinase K00849 galK; galactokinase [EC:2.7.1.6] D spr1667 galT; Galactose-1-phosphate uridylyltransferase K00965 galT; UDPglucose--hexose-1-phosphate uridylyltransferase [EC:2.7.7.12] D spr1648 galT; Galactose-1-phosphate uridylyltransferase K00965 galT; UDPglucose--hexose-1-phosphate uridylyltransferase [EC:2.7.7.12] D spr1683 UDP-galactose 4-epimerase, truncation K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2] D spr1460 galE; UDP-glucose 4-epimerase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2] D spr1647 galE; UDP-glucose 4-epimerase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2] D spr1903 galU; UTP-glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D spr1351 pgm; Phosphoglucomutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2] D spr0584 glcK; Glucose kinase K25026 glk; glucokinase [EC:2.7.1.2] D spr0565 bgaA; beta-galactosidase precursor K01190 lacZ; beta-galactosidase [EC:3.2.1.23] D spr0059 bgaC; Beta-galactosidase 3 K12308 bgaB; beta-galactosidase [EC:3.2.1.23] D spr0319 cps2P; The type 2 capsule locus of Streptococcus pneumoniae K01854 glf; UDP-galactopyranose mutase [EC:5.4.99.9] D spr1713 aga; Alpha-galactosidase (melibiase) K07407 E3.2.1.22B; alpha-galactosidase [EC:3.2.1.22] D spr1074 lacC; Tagatose-6-phosphate kinase K00917 lacC; tagatose 6-phosphate kinase [EC:2.7.1.144] D spr0796 pfkA; 6-phosphofructokinase I K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] D spr1073 lacD; Tagatose 1,6-diphosphate aldolase K01635 lacD; tagatose 1,6-diphosphate aldolase [EC:4.1.2.40] D spr1075 lacB; Galactose-6-phosphate isomerase LacB subunit K01819 E5.3.1.26; galactose-6-phosphate isomerase [EC:5.3.1.26] D spr1076 lacA; Galactose-6-phosphate isomerase LacA subunit K01819 E5.3.1.26; galactose-6-phosphate isomerase [EC:5.3.1.26] D spr0424 lacG; Phospho-beta-D-galactosidase K01220 E3.2.1.85; 6-phospho-beta-galactosidase [EC:3.2.1.85] D spr1069 lacG; Phospho-beta-D-galactosidase K01220 E3.2.1.85; 6-phospho-beta-galactosidase [EC:3.2.1.85] D spr0423 PTS-EII; Phosphotransferase system sugar-specific EII component K02786 lacF; lactose PTS system EIIA component [EC:2.7.1.207] D spr1071 lacF; PTS system, lactose-specific IIA component K02786 lacF; lactose PTS system EIIA component [EC:2.7.1.207] D spr0425 PTS-EII; Phosphotransferase system sugar-specific EII component K02788 lacE; lactose PTS system EIICB component [EC:2.7.1.207] D spr1070 lacE; PTS system, lactose-specific IIBC component K02788 lacE; lactose PTS system EIICB component [EC:2.7.1.207] D spr1568 scrB; Sucrose-6-phosphate hydrolase K01193 INV; beta-fructofuranosidase [EC:3.2.1.26] D spr1617 sacA; Sucrose-6-phosphate hydrolase K01193 INV; beta-fructofuranosidase [EC:3.2.1.26] D spr0291 PTS-EII; Phosphotransferase system sugar-specific EII component K02744 agaF; N-acetylgalactosamine PTS system EIIA component [EC:2.7.1.-] D spr0293 PTS-EII; Phosphotransferase system sugar-specific EII component K02745 agaV; N-acetylgalactosamine PTS system EIIB component [EC:2.7.1.-] D spr0294 PTS-EII; Phosphotransferase system sugar-specific EII component K02746 agaW; N-acetylgalactosamine PTS system EIIC component D spr0295 PTS-EII; Phosphotransferase system sugar-specific EII component K02747 agaE; N-acetylgalactosamine PTS system EIID component D spr0064 agaS; Tagatose-6-phosphate ketose/aldose isomerase K02082 agaS; D-galactosamine 6-phosphate deaminase/isomerase [EC:3.5.99.-] C 00053 Ascorbate and aldarate metabolism [PATH:spr00053] D spr0318 cps2K; The type 2 capsule locus of Streptococcus pneumoniae K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22] D spr0139 ugd; UDP-glucose dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22] D spr1847 PTS-EII; Phosphotransferase system sugar-specific EII component K02821 ulaC; ascorbate PTS system EIIA or EIIAB component [EC:2.7.1.194] D spr1848 PTS-EII; Phosphotransferase system sugar-specific EII component K02822 ulaB; ascorbate PTS system EIIB component [EC:2.7.1.194] D spr1939 Hypothetical protein K02822 ulaB; ascorbate PTS system EIIB component [EC:2.7.1.194] D spr1849 PTS-EII; Phosphotransferase system sugar-specific EII component K03475 ulaA; ascorbate PTS system EIIC component D spr1938 Conserved hypothetical protein K03475 ulaA; ascorbate PTS system EIIC component D spr1842 Conserved hypothetical protein K03476 ulaG; L-ascorbate 6-phosphate lactonase [EC:3.1.1.-] D spr1846 sgh; Hexulose-6-phosphate synthase (HumpS) K03078 ulaD; 3-dehydro-L-gulonate-6-phosphate decarboxylase [EC:4.1.1.85] D spr1845 sga; Hexulose-6-phosphate isomerase K03079 ulaE; L-ribulose-5-phosphate 3-epimerase [EC:5.1.3.22] D spr1844 araD; L-ribulose 5-phosphate 4-epimerase K03077 araD; L-ribulose-5-phosphate 4-epimerase [EC:5.1.3.4] C 00500 Starch and sucrose metabolism [PATH:spr00500] D spr1566 scrA; Phosphotransferase system enzyme II K02810 scrA; sucrose PTS system EIIBCA or EIIBC component [EC:2.7.1.211] D spr1568 scrB; Sucrose-6-phosphate hydrolase K01193 INV; beta-fructofuranosidase [EC:3.2.1.26] D spr1617 sacA; Sucrose-6-phosphate hydrolase K01193 INV; beta-fructofuranosidase [EC:3.2.1.26] D spr1709 gtfA; Dextransucrase (sucrose 6-glucosyltransferase) K00690 E2.4.1.7; sucrose phosphorylase [EC:2.4.1.7] D spr1903 galU; UTP-glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D spr1833 bgl2; Beta-glucosidase K05350 bglB; beta-glucosidase [EC:3.2.1.21] D spr0229 PTS-EIIA; Phosphotransferase system sugar-specific EIIA component K02759 celC; cellobiose PTS system EIIA component [EC:2.7.1.196 2.7.1.205] D spr0280 PTS-EII; Phosphotransferase system sugar-specific EII component K02759 celC; cellobiose PTS system EIIA component [EC:2.7.1.196 2.7.1.205] D spr1836 ptcA; Phosphotransferase system system, cellobiose-specific IIA component K02759 celC; cellobiose PTS system EIIA component [EC:2.7.1.196 2.7.1.205] D spr0230 PTS-EIIB; Phosphotransferase system sugar-specific EIIB component K02760 celA; cellobiose PTS system EIIB component [EC:2.7.1.196 2.7.1.205] D spr0278 PTS-EII; Phosphotransferase system sugar-specific EII component K02760 celA; cellobiose PTS system EIIB component [EC:2.7.1.196 2.7.1.205] D spr1835 ptcB; Phosphotransferase system system, cellobiose-specific IIB component K02760 celA; cellobiose PTS system EIIB component [EC:2.7.1.196 2.7.1.205] D spr1834 ptcC; Phosphotransferase system system, cellobiose-specific IIC component K02761 celB; cellobiose PTS system EIIC component D spr0231 PTS-EIIC; Phosphotransferase system sugar-specific EIIC component K02761 celB; cellobiose PTS system EIIC component D spr0282 PTS-EII; Phosphotransferase system sugar-specific EII component K02761 celB; cellobiose PTS system EIIC component D spr0421 PTS-EII; Phosphotransferase system sugar-specific EII component K02761 celB; cellobiose PTS system EIIC component D spr0276 bglA; 6-phospho-beta-glucosidase K01223 E3.2.1.86B; 6-phospho-beta-glucosidase [EC:3.2.1.86] D spr0506 bglH; 6-phospho-beta-glucosidase K01223 E3.2.1.86B; 6-phospho-beta-glucosidase [EC:3.2.1.86] D spr0244 bglA; 6-phospho-beta-glucosidase K01223 E3.2.1.86B; 6-phospho-beta-glucosidase [EC:3.2.1.86] D spr1031 glgD; Required for glycogen biosynthesis K00975 glgC; glucose-1-phosphate adenylyltransferase [EC:2.7.7.27] D spr1030 glgC; Glucose-1-phosphate adenylyltransferase K00975 glgC; glucose-1-phosphate adenylyltransferase [EC:2.7.7.27] D spr1032 glgA; Glycogen synthase K00703 glgA; starch synthase [EC:2.4.1.21] D spr1029 glgB; 1,4-alpha-glucan branching enzyme K00700 GBE1; 1,4-alpha-glucan branching enzyme [EC:2.4.1.18] D spr1916 malP; Maltodextrin phosphorylase K00688 PYG; glycogen phosphorylase [EC:2.4.1.1] D spr1025 pulI; Thermostable pullulanase K01200 pulA; pullulanase [EC:3.2.1.41] D spr1239 amy; Alpha-amylase precursor K01176 AMY; alpha-amylase [EC:3.2.1.1] D spr0948 nplT; Neopullulanase K01208 cd; cyclomaltodextrinase / maltogenic alpha-amylase / neopullulanase [EC:3.2.1.54 3.2.1.133 3.2.1.135] D spr1917 malM; 4-alpha-glucanotransferase (amylomaltase) K00705 malQ; 4-alpha-glucanotransferase [EC:2.4.1.25] D spr0668 ptsG; PTS glucose-specific enzyme IIABC component K20108 malT; maltose PTS system EIICB or EIICBA component [EC:2.7.1.208] D spr0669 Hypothetical protein K06896 mapP; maltose 6'-phosphate phosphatase [EC:3.1.3.90] D spr1699 treP; Phosphotransferase system, trehalose-specific IIBC component K02819 treB; trehalose PTS system EIIBC or EIIBCA component [EC:2.7.1.201] D spr1698 dexS; Dextran glucosidase K01226 treC; trehalose-6-phosphate hydrolase [EC:3.2.1.93] D spr1351 pgm; Phosphoglucomutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2] D spr0584 glcK; Glucose kinase K25026 glk; glucokinase [EC:2.7.1.2] D spr1882 gpi; Glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9] D spr1565 scrK; Fructokinase K00847 E2.7.1.4; fructokinase [EC:2.7.1.4] C 00520 Amino sugar and nucleotide sugar metabolism [PATH:spr00520] D spr0057 strH; Beta-N-acetyl-hexosaminidase precursor K12373 HEXA_B; hexosaminidase [EC:3.2.1.52] D spr1949 Hypothetical protein K12373 HEXA_B; hexosaminidase [EC:3.2.1.52] D spr1867 nagA; N-acetylglucosamine-6-phosphate deacetylase K01443 nagA; N-acetylglucosamine-6-phosphate deacetylase [EC:3.5.1.25] D spr1272 nagB; N-acetylglucosamine-6-phosphate isomerase K02564 nagB; glucosamine-6-phosphate deaminase [EC:3.5.99.6] D spr1565 scrK; Fructokinase K00847 E2.7.1.4; fructokinase [EC:2.7.1.4] D spr0245 glmS; L-glutamine-D-fructose-6-phosphate amidotransferase K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] D spr1417 glmM; Phosphoglucosamine mutase K03431 glmM; phosphoglucosamine mutase [EC:5.4.2.10] D spr0891 gcaD; UDP-N-acetylglucosamine pyrophosphorylase K04042 glmU; bifunctional UDP-N-acetylglucosamine pyrophosphorylase / glucosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.3.1.157] D spr0989 murZ; UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7] D spr1781 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7] D spr1247 murB; UDP-N-acetylenolpyruvoylglucosamine reductase K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98] D spr1529 nanE; N-acetylmannosamine-6-P epimerase K01788 nanE; N-acylglucosamine-6-phosphate 2-epimerase [EC:5.1.3.9] D spr1196 nanE; N-acetylmannosamine-6-P epimerase K01788 nanE; N-acylglucosamine-6-phosphate 2-epimerase [EC:5.1.3.9] D spr1520 N-acetylneuraminate lyase subunit, truncation K01639 E4.1.3.3; N-acetylneuraminate lyase [EC:4.1.3.3] D spr1186 N-acetylneuraminate lyase subunit, truncation K01639 E4.1.3.3; N-acetylneuraminate lyase [EC:4.1.3.3] D spr1528 PTS-EII; Phosphotransferase system sugar-specific EII component K02779 ptsG; glucose PTS system EIICB or EIICBA component [EC:2.7.1.199] D spr0584 glcK; Glucose kinase K25026 glk; glucokinase [EC:2.7.1.2] D spr1351 pgm; Phosphoglucomutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2] D spr1903 galU; UTP-glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D spr0318 cps2K; The type 2 capsule locus of Streptococcus pneumoniae K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22] D spr0139 ugd; UDP-glucose dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22] D spr1668 galK; Galactokinase K00849 galK; galactokinase [EC:2.7.1.6] D spr1667 galT; Galactose-1-phosphate uridylyltransferase K00965 galT; UDPglucose--hexose-1-phosphate uridylyltransferase [EC:2.7.7.12] D spr1648 galT; Galactose-1-phosphate uridylyltransferase K00965 galT; UDPglucose--hexose-1-phosphate uridylyltransferase [EC:2.7.7.12] D spr1683 UDP-galactose 4-epimerase, truncation K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2] D spr1460 galE; UDP-glucose 4-epimerase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2] D spr1647 galE; UDP-glucose 4-epimerase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2] D spr0319 cps2P; The type 2 capsule locus of Streptococcus pneumoniae K01854 glf; UDP-galactopyranose mutase [EC:5.4.99.9] D spr0063 PTS-EII; Phosphotransferase system sugar-specific EII component K02793 manXa; mannose PTS system EIIA component [EC:2.7.1.191] D spr1970 PTS-EII; Phosphotransferase system sugar-specific EII component K02793 manXa; mannose PTS system EIIA component [EC:2.7.1.191] D spr0261 manL; Phosphotransferase system, mannose-specific EIIAB K02794 manX; mannose PTS system EIIAB component [EC:2.7.1.191] D spr0061 PTS-EIIC; Phosphotransferase system sugar-specific EIIC component K02795 manY; mannose PTS system EIIC component D spr0260 manM; Phosphotransferase system, mannose-specific EIIC K02795 manY; mannose PTS system EIIC component D spr1968 PTS-EII; Phosphotransferase system sugar-specific EII component K02795 manY; mannose PTS system EIIC component D spr0062 PTS-EIID; Phosphotransferase system sugar-specific EIID component K02796 manZ; mannose PTS system EIID component D spr0259 manN; Phosphotransferase system, mannose-specific EIID K02796 manZ; mannose PTS system EIID component D spr1967 PTS-EII; Phosphotransferase system sugar-specific EII component K02796 manZ; mannose PTS system EIID component D spr1882 gpi; Glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9] D spr0647 pmi; Mannose-6-phosphate isomerase K01809 manA; mannose-6-phosphate isomerase [EC:5.3.1.8] D spr1031 glgD; Required for glycogen biosynthesis K00975 glgC; glucose-1-phosphate adenylyltransferase [EC:2.7.7.27] D spr1030 glgC; Glucose-1-phosphate adenylyltransferase K00975 glgC; glucose-1-phosphate adenylyltransferase [EC:2.7.7.27] C 00620 Pyruvate metabolism [PATH:spr00620] D spr1051 acoA; TPP-dependent acetoin dehydrogenase alpha chain K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1] D spr1050 acoB; TPP-dependent acetoin dehydrogenase beta chain K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1] D spr1049 acoC; Dihydrolipoamide S-acetyltransferase K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12] D spr1048 acoL; Dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D spr0415 pfl; Pyruvate formate-lyase K00656 E2.3.1.54; formate C-acetyltransferase [EC:2.3.1.54] D spr1837 adhE; Alcohol-acetaldehyde dehydrogenase K04072 adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1] D spr0262 adhP; Alcohol dehydrogenase, propanol-preferring K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1] D spr1854 ackA; Acetate kinase (acetokinase) K00925 ackA; acetate kinase [EC:2.7.2.1] D spr1007 pta; Phosphate acetyltransferase K00625 pta; phosphate acetyltransferase [EC:2.3.1.8] D spr0797 pykF; Pyruvate kinase I; fructose-stimulated K00873 PK; pyruvate kinase [EC:2.7.1.40] D spr0387 accA; Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha K01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15] D spr0383 accB; Biotin carboxyl carrier protein of acetyl-CoA carboxylase K02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein D spr0385 accC; Biotin carboxylase (a subunit of acetyl-CoA carboxylase (ACC) K01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14] D spr0386 accD; Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta K01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15] D spr1789 acyP; Acylphosphate phosphohydrolase K01512 acyP; acylphosphatase [EC:3.6.1.7] D spr0642 spxB; Pyruvate oxidase K00158 spxB; pyruvate oxidase [EC:1.2.3.3] D spr1100 ldh; L-lactate dehydrogenase K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27] D spr0864 lguL; Lactoylglutathione lyase K01759 GLO1; lactoylglutathione lyase [EC:4.4.1.5] D spr1490 Conserved hypothetical protein K01069 gloB; hydroxyacylglutathione hydrolase [EC:3.1.2.6] D spr0974 ppc; Phosphoenolpyruvate carboxylase K01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31] C 00630 Glyoxylate and dicarboxylate metabolism [PATH:spr00630] D spr0093 gph; Phosphoglycolate phosphatase K01091 gph; phosphoglycolate phosphatase [EC:3.1.3.18] D spr0444 glnA; Glutamine synthetase type 1 K01915 glnA; glutamine synthetase [EC:6.3.1.2] D spr0928 glyA; Serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D spr1048 acoL; Dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D spr1034 glxK; Glycerate kinase K00865 glxK; glycerate 2-kinase [EC:2.7.1.165] D spr0287 kdgA; 2-keto-3-deoxy-6-phosphogluconate aldolase K01625 eda; 2-dehydro-3-deoxyphosphogluconate aldolase / (4S)-4-hydroxy-2-oxoglutarate aldolase [EC:4.1.2.14 4.1.3.42] C 00640 Propanoate metabolism [PATH:spr00640] D spr1854 ackA; Acetate kinase (acetokinase) K00925 ackA; acetate kinase [EC:2.7.2.1] D spr1007 pta; Phosphate acetyltransferase K00625 pta; phosphate acetyltransferase [EC:2.3.1.8] D spr1048 acoL; Dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D spr0415 pfl; Pyruvate formate-lyase K00656 E2.3.1.54; formate C-acetyltransferase [EC:2.3.1.54] D spr0387 accA; Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha K01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15] D spr0383 accB; Biotin carboxyl carrier protein of acetyl-CoA carboxylase K02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein D spr0385 accC; Biotin carboxylase (a subunit of acetyl-CoA carboxylase (ACC) K01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14] D spr0386 accD; Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta K01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15] D spr1100 ldh; L-lactate dehydrogenase K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27] D spr0234 gldA; Glycerol dehydrogenase, NAD+ dependent K00005 gldA; glycerol dehydrogenase [EC:1.1.1.6] C 00650 Butanoate metabolism [PATH:spr00650] D spr1837 adhE; Alcohol-acetaldehyde dehydrogenase K04072 adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1] D spr0415 pfl; Pyruvate formate-lyase K00656 E2.3.1.54; formate C-acetyltransferase [EC:2.3.1.54] D spr1571 mvaS; 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) synthase K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10] D spr1866 adh; Putative alcohol dehydrogenase K18369 adh2; alcohol dehydrogenase [EC:1.1.1.-] D spr0401 ilvB; Acetolactate synthase large subunit K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D spr0402 ilvN; Acetolactate synthase small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6] D spr1249 aldB; Alpha-acetolactate decarboxylase K01575 alsD; acetolactate decarboxylase [EC:4.1.1.5] C 00660 C5-Branched dibasic acid metabolism [PATH:spr00660] D spr0401 ilvB; Acetolactate synthase large subunit K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D spr0402 ilvN; Acetolactate synthase small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6] D spr1249 aldB; Alpha-acetolactate decarboxylase K01575 alsD; acetolactate decarboxylase [EC:4.1.1.5] D spr1133 3-isopropylmalate dehydratase small subunit, truncation K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35] D spr1135 leuB; 3-isopropylmalate dehydrogenase K00052 leuB; 3-isopropylmalate dehydrogenase [EC:1.1.1.85] C 00562 Inositol phosphate metabolism [PATH:spr00562] D spr1260 Conserved hypothetical protein K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25] D spr1432 tpi; Triose phosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] B B 09102 Energy metabolism C 00190 Oxidative phosphorylation [PATH:spr00190] D spr1362 atpA; Proton-translocating ATPase, F1 sector, alpha-subunit K02111 ATPF1A; F-type H+/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1] D spr1360 atpD; Proton-translocating ATPase, F1 sector, beta-subunit K02112 ATPF1B; F-type H+/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1] D spr1361 atpG; Proton-translocating ATPase, F1 sector, gamma-subunit K02115 ATPF1G; F-type H+-transporting ATPase subunit gamma D spr1363 atpH; Proton-translocating ATPase, F1 sector, delta-subunit K02113 ATPF1D; F-type H+-transporting ATPase subunit delta D spr1359 atpC; Proton-translocating ATPase, F1 sector, epsilon-subunit K02114 ATPF1E; F-type H+-transporting ATPase subunit epsilon D spr1365 atpB; Proton-translocating ATPase, F0 sector, subunit a K02108 ATPF0A; F-type H+-transporting ATPase subunit a D spr1364 atpF; Proton-translocating ATPase, F0 sector, subunit b K02109 ATPF0B; F-type H+-transporting ATPase subunit b D spr1366 atpE; Proton-translocating ATPase, F0 sector, subunit c K02110 ATPF0C; F-type H+-transporting ATPase subunit c D spr1389 ppaC; Manganese-dependent inorganic pyrophosphatase K15986 ppaC; manganese-dependent inorganic pyrophosphatase [EC:3.6.1.1] C 00195 Photosynthesis C 00196 Photosynthesis - antenna proteins C 00710 Carbon fixation by Calvin cycle [PATH:spr00710] D spr0441 pgk; Phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3] D spr1825 gapA; Glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] D spr0530 fba; Fructose-bisphosphate aldolase K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13] D spr1841 tktA; Transketolase K00615 E2.2.1.1; transketolase [EC:2.2.1.1] D spr1936 tktC; Putative transketolase c-terminal section K00615 E2.2.1.1; transketolase [EC:2.2.1.1] D spr1937 tktN; Putative transketolase n-terminal section K00615 E2.2.1.1; transketolase [EC:2.2.1.1] D spr0731 rpiA; Ribose-5-phosphate epimerase K01807 rpiA; ribose 5-phosphate isomerase A [EC:5.3.1.6] D spr1432 tpi; Triose phosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] D spr1797 rpe; Pentose-5-phosphate-3-epimerase K01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1] D spr0974 ppc; Phosphoenolpyruvate carboxylase K01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31] C 00720 Other carbon fixation pathways [PATH:spr00720] D spr0974 ppc; Phosphoenolpyruvate carboxylase K01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31] D spr0387 accA; Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha K01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15] D spr0383 accB; Biotin carboxyl carrier protein of acetyl-CoA carboxylase K02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein D spr0385 accC; Biotin carboxylase (a subunit of acetyl-CoA carboxylase (ACC) K01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14] D spr0386 accD; Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta K01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15] D spr1109 fhs; Formate--tetrahydrofolate ligase K01938 fhs; formate--tetrahydrofolate ligase [EC:6.3.4.3] D spr0729 folD; Fold bifunctional protein; includes: methylenetetrahydrofolate dehydrogenase, methenyltetrahydrofolate cyclohydrolase K01491 folD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9] D spr0515 metF; 5,10-methylenetetrahydrofolate reductase K00297 metF; methylenetetrahydrofolate reductase (NADH) [EC:1.5.1.54] D spr1007 pta; Phosphate acetyltransferase K00625 pta; phosphate acetyltransferase [EC:2.3.1.8] D spr1854 ackA; Acetate kinase (acetokinase) K00925 ackA; acetate kinase [EC:2.7.2.1] C 00680 Methane metabolism [PATH:spr00680] D spr0928 glyA; Serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D spr1036 eno; Enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D spr0974 ppc; Phosphoenolpyruvate carboxylase K01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31] D spr0530 fba; Fructose-bisphosphate aldolase K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13] D spr0796 pfkA; 6-phosphofructokinase I K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] D spr1854 ackA; Acetate kinase (acetokinase) K00925 ackA; acetate kinase [EC:2.7.2.1] D spr1007 pta; Phosphate acetyltransferase K00625 pta; phosphate acetyltransferase [EC:2.3.1.8] D spr1499 gpmA; Phosphoglyceromutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] C 00910 Nitrogen metabolism [PATH:spr00910] D spr1181 gdhA; NADP-specific glutamate dehydrogenase K00262 E1.4.1.4; glutamate dehydrogenase (NADP+) [EC:1.4.1.4] D spr0444 glnA; Glutamine synthetase type 1 K01915 glnA; glutamine synthetase [EC:6.3.1.2] D spr1958 arcC; Carbamate kinase K00926 arcC; carbamate kinase [EC:2.7.2.2] D spr0026 Conserved hypothetical protein K01673 cynT; carbonic anhydrase [EC:4.2.1.1] C 00920 Sulfur metabolism [PATH:spr00920] D spr1176 Conserved hypothetical protein K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3] D spr0517 cysE; Serine acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30] D spr2015 cycK; Cysteine synthase, O-acetylserine sulfhydrylase K01738 cysK; cysteine synthase [EC:2.5.1.47] D spr1434 metA; Homoserine O-succinyltransferase K00651 metA; homoserine O-succinyltransferase/O-acetyltransferase [EC:2.3.1.46 2.3.1.31] D spr1377 metB; Cystathionine gamma-synthase K01739 metB; cystathionine gamma-synthase [EC:2.5.1.48] B B 09103 Lipid metabolism C 00061 Fatty acid biosynthesis [PATH:spr00061] D spr0387 accA; Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha K01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15] D spr0383 accB; Biotin carboxyl carrier protein of acetyl-CoA carboxylase K02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein D spr0385 accC; Biotin carboxylase (a subunit of acetyl-CoA carboxylase (ACC) K01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14] D spr0386 accD; Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta K01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15] D spr0038 acpP; Acyl carrier protein K02078 acpP; acyl carrier protein D spr0378 acp; Acyl carrier protein K02078 acpP; acyl carrier protein D spr0380 fabD; Malonyl acyl carrier protein transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39] D spr0377 fabH; 3-oxoacyl-acyl-carrier-protein synthase III K00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180] D spr0382 fabF; Beta ketoacyl-acyl carrier protein synthase K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179] D spr0381 fabG; 3-ketoacyl-acyl carrier protein reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D spr0701 fabG; 3-Ketoacyl-ACP reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D spr0384 fabZ; Hydroxymyristoyl-(acyl carrier protein) dehydratase K02372 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59] D spr0379 fabK; Enoyl-acyl carrier protein(ACP) reductase K02371 fabK; enoyl-[acyl-carrier protein] reductase II [EC:1.3.1.9] D spr0375 phaB; Enoyl-CoA hydratase II K18474 fabM; trans-2-decenoyl-[acyl-carrier protein] isomerase [EC:5.3.3.14] D spr0966 Conserved hypothetical protein K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] C 00062 Fatty acid elongation C 00071 Fatty acid degradation [PATH:spr00071] D spr0966 Conserved hypothetical protein K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D spr1837 adhE; Alcohol-acetaldehyde dehydrogenase K04072 adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1] D spr0262 adhP; Alcohol dehydrogenase, propanol-preferring K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1] C 00073 Cutin, suberine and wax biosynthesis C 00074 Mycolic acid biosynthesis [PATH:spr00074] D spr1541 acpS; Acyl Carrier protein synthase K00997 acpS; holo-[acyl-carrier protein] synthase [EC:2.7.8.7] D spr0038 acpP; Acyl carrier protein K02078 acpP; acyl carrier protein D spr0378 acp; Acyl carrier protein K02078 acpP; acyl carrier protein D spr0380 fabD; Malonyl acyl carrier protein transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39] C 00100 Steroid biosynthesis C 00120 Primary bile acid biosynthesis C 00121 Secondary bile acid biosynthesis C 00140 Steroid hormone biosynthesis C 00561 Glycerolipid metabolism [PATH:spr00561] D spr1034 glxK; Glycerate kinase K00865 glxK; glycerate 2-kinase [EC:2.7.1.165] D spr0234 gldA; Glycerol dehydrogenase, NAD+ dependent K00005 gldA; glycerol dehydrogenase [EC:1.1.1.6] D spr1991 glpK; Glycerol kinase K00864 glpK; glycerol kinase [EC:2.7.1.30] D spr0037 plsX; Involved in fatty acid/phospholipid synthesis K03621 plsX; phosphate acyltransferase [EC:2.3.1.274] D spr0755 Conserved hypothetical protein K08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275] D spr1465 Conserved hypothetical protein K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51] D spr0982 Conserved Hypothetical protein K19002 mgs; 1,2-diacylglycerol 3-alpha-glucosyltransferase [EC:2.4.1.337] D spr1713 aga; Alpha-galactosidase (melibiase) K07407 E3.2.1.22B; alpha-galactosidase [EC:3.2.1.22] C 00564 Glycerophospholipid metabolism [PATH:spr00564] D spr1902 gpdA; Glycerol-3-phosphate dehydrogenase (NAD(P)+) K00057 gpsA; glycerol-3-phosphate dehydrogenase (NAD(P)+) [EC:1.1.1.94] D spr1990 Glycerol-3-phosphate dehydrogenase, truncation K00105 E1.1.3.21; alpha-glycerophosphate oxidase [EC:1.1.3.21] D spr0755 Conserved hypothetical protein K08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275] D spr1465 Conserved hypothetical protein K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51] D spr0897 Hypothetical protein K01126 E3.1.4.46; glycerophosphoryl diester phosphodiesterase [EC:3.1.4.46] D spr0241 cdsA; Phosphatidate cytidylyltransferase K00981 E2.7.7.41; phosphatidate cytidylyltransferase [EC:2.7.7.41] D spr2027 pgsA; Phosphotidylglycerophosphate synthase K00995 PGS1; CDP-diacylglycerol---glycerol-3-phosphate 3-phosphatidyltransferase [EC:2.7.8.5] D spr0180 cls; Cardiolipin synthase K06131 clsA_B; cardiolipin synthase A/B [EC:2.7.8.-] C 00565 Ether lipid metabolism C 00600 Sphingolipid metabolism [PATH:spr00600] D spr0565 bgaA; beta-galactosidase precursor K01190 lacZ; beta-galactosidase [EC:3.2.1.23] D spr1531 nanB; Sialidase B precursor (neuraminidase B) K01186 NEU1; sialidase-1 [EC:3.2.1.18] D spr1536 nanA; Sialidase A precursor (neuraminidase A) K01186 NEU1; sialidase-1 [EC:3.2.1.18] D spr1713 aga; Alpha-galactosidase (melibiase) K07407 E3.2.1.22B; alpha-galactosidase [EC:3.2.1.22] D spr0057 strH; Beta-N-acetyl-hexosaminidase precursor K12373 HEXA_B; hexosaminidase [EC:3.2.1.52] D spr1949 Hypothetical protein K12373 HEXA_B; hexosaminidase [EC:3.2.1.52] C 00590 Arachidonic acid metabolism C 00591 Linoleic acid metabolism C 00592 alpha-Linolenic acid metabolism C 01040 Biosynthesis of unsaturated fatty acids B B 09104 Nucleotide metabolism C 00230 Purine metabolism [PATH:spr00230] D spr0892 Conserved hypothetical protein K01515 nudF; ADP-ribose diphosphatase [EC:3.6.1.13 3.6.1.-] D spr0732 deoB; phosphodeoxyribomutase K01839 deoB; phosphopentomutase [EC:5.4.2.7] D spr1351 pgm; Phosphoglucomutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2] D spr0028 prsA; Phosphoribosylpyrophosphate synthase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1] D spr1002 prs; Ribose-phosphate pyrophosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1] D spr0047 purF; Amidophosphoribosyl transferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14] D spr0052 purD; Phosphoribosylglycinamide synthetase K01945 purD; phosphoribosylamine---glycine ligase [EC:6.3.4.13] D spr0049 purN; 5'-phosphoribosylglycinamide transformylase 1 K11175 purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2] D spr0046 purL; Phosphoribosylformylglycinamide synthetase K01952 PFAS; phosphoribosylformylglycinamidine synthase [EC:6.3.5.3] D spr0048 purM; Phosphoribosylaminoimidazole synthetase K01933 purM; phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.3.1] D spr0054 purK; Phosphoribosyl glucinamide formyltransferase K01589 purK; 5-(carboxyamino)imidazole ribonucleotide synthase [EC:6.3.4.18] D spr0053 purE; Phosphoribosylaminoimidazole carboxylase, catalytic subunit K01588 purE; 5-(carboxyamino)imidazole ribonucleotide mutase [EC:5.4.99.18] D spr0045 purC; Phosphoribosylaminoimidazole-succinocarboxamide synthetase K01923 purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:6.3.2.6] D spr0056 purB; Adenylosuccinate lyase K01756 purB; adenylosuccinate lyase [EC:4.3.2.2] D spr0051 purH; Phosphoribosylaminoimidazolecarboxamide formyltransferase K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10] D spr1435 apt; Adenine phosphoribosyltransferase K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7] D spr0734 pnp; Purine nucleoside phosphorylase (inosine phosphorylase) K03783 punA; purine-nucleoside phosphorylase [EC:2.4.2.1] D spr0738 deoD; Purine nucleoside phosphorylase (inosine phosphorylase) K03784 deoD; purine-nucleoside phosphorylase [EC:2.4.2.1] D spr0011 hgt; Hypoxanthine guanine phosphoribosyltransferase K00760 hprT; hypoxanthine phosphoribosyltransferase [EC:2.4.2.8] D spr2033 imdH; Inosine-5'-monophosphate dehydrogenase K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205] D spr1775 ndk; Nucleoside diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6] D spr1695 Hypothetical protein K01519 rdgB; XTP/dITP diphosphohydrolase [EC:3.6.1.66] D spr1662 xpt; Xanthine phosphoribosyltransferase K03816 xpt; xanthine phosphoribosyltransferase [EC:2.4.2.22] D spr1300 guaA; Glutamine amidotransferase K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] D spr1128 guaC; GMP reductase K00364 guaC; GMP reductase [EC:1.7.1.7] D spr1583 gmk; Guanylate kinase K00942 gmk; guanylate kinase [EC:2.7.4.8] D spr1065 nrdE; Ribonucleoside-diphosphate reductase (major subunit) K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D spr1066 nrdF; Nonessential ribonucleoside-diP reductase 2, subunit beta, class I, function unknown K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1] D spr0183 nrdD; Ribonucleotide reductase, class III, anaerobic K21636 nrdD; ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6] D spr1487 relA; GTP pyrophosphokinase K01139 spoT; GTP diphosphokinase / guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2] D spr1004 Similar to GTP pyrophosphokinase K07816 E2.7.6.5; GTP pyrophosphokinase [EC:2.7.6.5] D spr0021 purA; Adenylosuccinate synthetase K01939 purA; adenylosuccinate synthase [EC:6.3.4.4] D spr0210 adk; Adenylate kinase (ATP-AMP transphosphorylase) K00939 adk; adenylate kinase [EC:2.7.4.3] D spr1958 arcC; Carbamate kinase K00926 arcC; carbamate kinase [EC:2.7.2.2] C 00240 Pyrimidine metabolism [PATH:spr00240] D spr1153 carB; Carbamoylphosphate synthase (ammonia), heavy subunit K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5] D spr1154 carA; Carbamoylphosphate synthase (glutamine-hydrolysing) light subunit K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5] D spr1155 pyrB; Aspartate carbamoyltransferase K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2] D spr1053 pyrC; Dihydroorotase K01465 URA4; dihydroorotase [EC:3.5.2.3] D spr0866 pyrD; Dihydroorotate dehydrogenase K17828 pyrDI; dihydroorotate dehydrogenase (NAD+) catalytic subunit [EC:1.3.1.14] D spr0865 pyrDII; Dihydroorotate dehydrogenase electron transfer subunit K02823 pyrDII; dihydroorotate dehydrogenase electron transfer subunit D spr0672 pyrDA; Dihydroorotate dehydrogenase K00226 pyrD; dihydroorotate dehydrogenase (fumarate) [EC:1.3.98.1] D spr0614 pyrE; Orotate phosphoribosyltransferase K00762 pyrE; orotate phosphoribosyltransferase [EC:2.4.2.10] D spr0613 pyrF; Orotidine-5'-decarboxylase K01591 pyrF; orotidine-5'-phosphate decarboxylase [EC:4.1.1.23] D spr0845 pyrH; UMP kinase K09903 pyrH; uridylate kinase [EC:2.7.4.22] D spr1775 ndk; Nucleoside diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6] D spr0438 pyrG; CTP synthetase K01937 pyrG; CTP synthase [EC:6.3.4.2] D spr1456 cmk; Cytidylate kinase K00945 cmk; CMP/dCMP kinase [EC:2.7.4.25] D spr1090 udK; Uridine kinase K00876 udk; uridine kinase [EC:2.7.1.48] D spr0186 Hypothetical protein K00876 udk; uridine kinase [EC:2.7.1.48] D spr1057 Conserved hypothetical protein K25434 pynA; pyrimidine 5'-nucleotidase [EC:3.1.3.-] D spr0655 upp; Uracil phosphoribosyltransferase K00761 upp; uracil phosphoribosyltransferase [EC:2.4.2.9] D spr1156 pyrR; Transcriptional attenuation of the pyrimidine operon / uracil phosphoribosyltransferase activity K02825 pyrR; pyrimidine operon attenuation protein / uracil phosphoribosyltransferase [EC:2.4.2.9] D spr0744 pdp; Pyrimidine nucleoside phosphorylase K00756 pdp; pyrimidine-nucleoside phosphorylase [EC:2.4.2.2] D spr0746 cdd; Cytidine deaminase K01489 cdd; cytidine deaminase [EC:3.5.4.5] D spr1188 cdd; Cytidine deaminase K01489 cdd; cytidine deaminase [EC:3.5.4.5] D spr0183 nrdD; Ribonucleotide reductase, class III, anaerobic K21636 nrdD; ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6] D spr1065 nrdE; Ribonucleoside-diphosphate reductase (major subunit) K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D spr1066 nrdF; Nonessential ribonucleoside-diP reductase 2, subunit beta, class I, function unknown K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1] D spr0654 comEB; dCMP deaminase K01493 comEB; dCMP deaminase [EC:3.5.4.12] D spr0835 tmk; Thymidylate kinase K00943 tmk; dTMP kinase [EC:2.7.4.9] D spr0023 dut; Deoxyuridinetriphosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23] D spr0922 tdk; Thymidine kinase K00857 tdk; thymidine kinase [EC:2.7.1.21] D spr0585 thyA; Thymidylate synthase K00560 thyA; thymidylate synthase [EC:2.1.1.45] D spr1725 ydfG; Oxidoreductase K16066 ydfG; 3-hydroxy acid dehydrogenase / malonic semialdehyde reductase [EC:1.1.1.381 1.1.1.-] B B 09105 Amino acid metabolism C 00250 Alanine, aspartate and glutamate metabolism [PATH:spr00250] D spr1812 ansB; L-asparaginase (L-asparagine amidohydrolase) K01424 E3.5.1.1; L-asparaginase [EC:3.5.1.1] D spr1785 asnA; Aspartate--ammonia ligase (asparagine synthetase A) K01914 asnA; aspartate--ammonia ligase [EC:6.3.1.1] D spr1399 aspB; Aspartate aminotransferase K22457 E2.6.1.14; asparagine---oxo-acid transaminase [EC:2.6.1.14] D spr1808 aspC; Potential aminotransferase K14260 alaA; alanine-synthesizing transaminase [EC:2.6.1.66 2.6.1.2] D spr0102 argG; Argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5] D spr0103 argH; Arginine succinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1] D spr0021 purA; Adenylosuccinate synthetase K01939 purA; adenylosuccinate synthase [EC:6.3.4.4] D spr0056 purB; Adenylosuccinate lyase K01756 purB; adenylosuccinate lyase [EC:4.3.2.2] D spr1155 pyrB; Aspartate carbamoyltransferase K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2] D spr1181 gdhA; NADP-specific glutamate dehydrogenase K00262 E1.4.1.4; glutamate dehydrogenase (NADP+) [EC:1.4.1.4] D spr0444 glnA; Glutamine synthetase type 1 K01915 glnA; glutamine synthetase [EC:6.3.1.2] D spr1153 carB; Carbamoylphosphate synthase (ammonia), heavy subunit K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5] D spr1154 carA; Carbamoylphosphate synthase (glutamine-hydrolysing) light subunit K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5] D spr0245 glmS; L-glutamine-D-fructose-6-phosphate amidotransferase K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] D spr0047 purF; Amidophosphoribosyl transferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14] C 00260 Glycine, serine and threonine metabolism [PATH:spr00260] D spr0374 lysC; Aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4] D spr0918 asd; Aspartate beta-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11] D spr1219 hom; Homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3] D spr1218 thrB; Homoserine kinase K00872 thrB; homoserine kinase [EC:2.7.1.39] D spr1878 thrC; Threonine synthase K01733 thrC; threonine synthase [EC:4.2.3.1] D spr0928 glyA; Serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D spr1034 glxK; Glycerate kinase K00865 glxK; glycerate 2-kinase [EC:2.7.1.165] D spr1499 gpmA; Phosphoglyceromutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] D spr1725 ydfG; Oxidoreductase K16066 ydfG; 3-hydroxy acid dehydrogenase / malonic semialdehyde reductase [EC:1.1.1.381 1.1.1.-] D spr1048 acoL; Dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D spr0094 sdaA; L-serine dehydratase alpha subunit K01752 E4.3.1.17; L-serine dehydratase [EC:4.3.1.17] D spr0095 sdaB; L-serine dehydratase beta subunit K01752 E4.3.1.17; L-serine dehydratase [EC:4.3.1.17] D spr0406 ilvA; Threonine desaminase K01754 E4.3.1.19; threonine dehydratase [EC:4.3.1.19] D spr1631 trpA; Tryptophan synthase alpha chain K01695 trpA; tryptophan synthase alpha chain [EC:4.2.1.20] D spr1632 trpB; Tryptophan synthase beta chain K01696 trpB; tryptophan synthase beta chain [EC:4.2.1.20] C 00270 Cysteine and methionine metabolism [PATH:spr00270] D spr0517 cysE; Serine acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30] D spr2015 cycK; Cysteine synthase, O-acetylserine sulfhydrylase K01738 cysK; cysteine synthase [EC:2.5.1.47] D spr1376 patB; Aminotransferase K14155 patB; cysteine-S-conjugate beta-lyase [EC:4.4.1.13] D spr0514 metE; Tetrahydropteroyltriglutamate methyltransferase K00549 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14] D spr0671 metK; S-adenosylmethionine synthetase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6] D spr0819 speE; Spermidine synthase K00797 speE; spermidine synthase [EC:2.5.1.16] D spr0894 pfs; 5'-methylthioadenosine / S-adenosylhomocysteine nucleosidase K01243 mtnN; adenosylhomocysteine nucleosidase [EC:3.2.2.9] D spr1214 trzA; N-ethylammeline chlorohydrolase K12960 mtaD; 5-methylthioadenosine/S-adenosylhomocysteine deaminase [EC:3.5.4.31 3.5.4.28] D spr0768 Conserved hypothetical protein K08968 msrC; L-methionine (R)-S-oxide reductase [EC:1.8.4.14] D spr0308 luxS; Autoinducer-2 production protein K07173 luxS; S-ribosylhomocysteine lyase [EC:4.4.1.21] D spr0374 lysC; Aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4] D spr0918 asd; Aspartate beta-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11] D spr1219 hom; Homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3] D spr1218 thrB; Homoserine kinase K00872 thrB; homoserine kinase [EC:2.7.1.39] D spr1434 metA; Homoserine O-succinyltransferase K00651 metA; homoserine O-succinyltransferase/O-acetyltransferase [EC:2.3.1.46 2.3.1.31] D spr1377 metB; Cystathionine gamma-synthase K01739 metB; cystathionine gamma-synthase [EC:2.5.1.48] D spr1095 O-acetylhomoserine sulfhydrylase, truncation K01740 metY; O-acetylhomoserine (thiol)-lyase [EC:2.5.1.49] D spr0758 ilvE; Branched-chain-amino-acid transaminase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] D spr1100 ldh; L-lactate dehydrogenase K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27] D spr0094 sdaA; L-serine dehydratase alpha subunit K01752 E4.3.1.17; L-serine dehydratase [EC:4.3.1.17] D spr0095 sdaB; L-serine dehydratase beta subunit K01752 E4.3.1.17; L-serine dehydratase [EC:4.3.1.17] C 00280 Valine, leucine and isoleucine degradation [PATH:spr00280] D spr0758 ilvE; Branched-chain-amino-acid transaminase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] D spr1048 acoL; Dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D spr1571 mvaS; 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) synthase K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10] C 00290 Valine, leucine and isoleucine biosynthesis [PATH:spr00290] D spr0406 ilvA; Threonine desaminase K01754 E4.3.1.19; threonine dehydratase [EC:4.3.1.19] D spr1133 3-isopropylmalate dehydratase small subunit, truncation K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35] D spr1135 leuB; 3-isopropylmalate dehydrogenase K00052 leuB; 3-isopropylmalate dehydrogenase [EC:1.1.1.85] D spr0401 ilvB; Acetolactate synthase large subunit K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D spr0402 ilvN; Acetolactate synthase small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6] D spr0403 ilvC; Ketol-acid reductoisomerase K00053 ilvC; ketol-acid reductoisomerase [EC:1.1.1.86] D spr1935 ilvD; Dihydroxyacid dehydratase K01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9] D spr0758 ilvE; Branched-chain-amino-acid transaminase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] D spr1808 aspC; Potential aminotransferase K14260 alaA; alanine-synthesizing transaminase [EC:2.6.1.66 2.6.1.2] C 00300 Lysine biosynthesis [PATH:spr00300] D spr1219 hom; Homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3] D spr0374 lysC; Aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4] D spr0918 asd; Aspartate beta-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11] D spr0919 dapA; Dihydrodipicolinate synthase K01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7] D spr1414 dapB; Dihydrodipicolinate reductase K00215 dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8] D spr1907 dapD; 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase-related protein K00674 dapD; 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [EC:2.3.1.117] D spr0148 dapE; Succinyl-diaminopimelic descuccinlyase (ArgE/DapE/Acy1 family protein) K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18] D spr1792 lysA; Diaminopimelate decarboxylase K01586 lysA; diaminopimelate decarboxylase [EC:4.1.1.20] D spr0035 aspC; Aspartate aminotransferase K00841 patA; aminotransferase [EC:2.6.1.-] D spr1906 hipO; Similar to several hippurate hydrolases and amino acid amidohydrolases; can be a peptidase too K05823 dapL; N-acetyldiaminopimelate deacetylase [EC:3.5.1.47] D spr1514 murF; UDP-N-acetylmuramoylalanine-D-glutamyl-lysine-D-alanyl-D-alanine ligase K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10] C 00310 Lysine degradation D spr1048 acoL; Dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] C 00220 Arginine biosynthesis [PATH:spr00220] D spr1957 arcB; Ornithine transcarbamoylase K00611 OTC; ornithine carbamoyltransferase [EC:2.1.3.3] D spr0102 argG; Argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5] D spr0103 argH; Arginine succinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1] D spr0444 glnA; Glutamine synthetase type 1 K01915 glnA; glutamine synthetase [EC:6.3.1.2] D spr1153 carB; Carbamoylphosphate synthase (ammonia), heavy subunit K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5] D spr1154 carA; Carbamoylphosphate synthase (glutamine-hydrolysing) light subunit K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5] D spr1958 arcC; Carbamate kinase K00926 arcC; carbamate kinase [EC:2.7.2.2] D spr1181 gdhA; NADP-specific glutamate dehydrogenase K00262 E1.4.1.4; glutamate dehydrogenase (NADP+) [EC:1.4.1.4] D spr1808 aspC; Potential aminotransferase K14260 alaA; alanine-synthesizing transaminase [EC:2.6.1.66 2.6.1.2] C 00330 Arginine and proline metabolism [PATH:spr00330] D spr0816 cad; Lysine decarboxylase K01585 speA; arginine decarboxylase [EC:4.1.1.19] D spr0822 Conserved hypothetical protein K10536 aguA; agmatine deiminase [EC:3.5.3.12] D spr0823 but; Beta-alanine synthase or beta-ureidopropionase K12251 aguB; N-carbamoylputrescine amidase [EC:3.5.1.53] D spr0820 Conserved hypothetical protein K27502 capadh; carboxyaminopropylagmatine dehydrogenase [EC:1.5.1.55] D spr0821 nspC; Carboxynorspermidine decarboxylase K27684 capadc; carboxyaminopropylagmatine decarboxylase [EC:4.1.1.127] D spr0819 speE; Spermidine synthase K00797 speE; spermidine synthase [EC:2.5.1.16] D spr0923 bltD; Spermine/spermidine acetyltransferase K00657 speG; diamine N-acetyltransferase [EC:2.3.1.57] D spr0834 proC; Pyrroline-5-carboxylate reductase K00286 proC; pyrroline-5-carboxylate reductase [EC:1.5.1.2] D spr0832 proB; Gamma-glutamyl kinase K00931 proB; glutamate 5-kinase [EC:2.7.2.11] D spr0833 proA; Gamma-glutamyl phosphate reductase K00147 proA; glutamate-5-semialdehyde dehydrogenase [EC:1.2.1.41] C 00340 Histidine metabolism C 00350 Tyrosine metabolism D spr1837 adhE; Alcohol-acetaldehyde dehydrogenase K04072 adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1] D spr0262 adhP; Alcohol dehydrogenase, propanol-preferring K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1] C 00360 Phenylalanine metabolism C 00380 Tryptophan metabolism D spr1048 acoL; Dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] C 00400 Phenylalanine, tyrosine and tryptophan biosynthesis [PATH:spr00400] D spr1542 aroF; Phospho-2-dehydro-3-deoxyheptonate aldolase (DAHP synthatase); possibly tyr-sensitive K01626 E2.5.1.54; 3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54] D spr1543 aroG; phospho-2-dehydro-3-deoxyheptonate aldolase (DAHP synthatase isozyme)-possibly phe sensitive K01626 E2.5.1.54; 3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54] D spr1233 aroB; 3-dehydroquinate synthase K01735 aroB; 3-dehydroquinate synthase [EC:4.2.3.4] D spr1235 aroD; 3-dehydroquinate dehydratase K03785 aroD; 3-dehydroquinate dehydratase I [EC:4.2.1.10] D spr1228 aroK; Shikimate kinase K00891 aroK; shikimate kinase [EC:2.7.1.71] D spr1229 aroA; 3-Enolpyruvylshikimate-5-phosphate synthetase K00800 aroA; 3-phosphoshikimate 1-carboxyvinyltransferase [EC:2.5.1.19] D spr1232 aroC; Chorismate synthase K01736 aroC; chorismate synthase [EC:4.2.3.5] D spr1637 trpE; Anthranilate synthase component I K01657 trpE; anthranilate synthase component I [EC:4.1.3.27] D spr1636 trpG; Anthranilate synthase component II (glutamine amido-transferase) K01658 trpG; anthranilate synthase component II [EC:4.1.3.27] D spr1635 trpD; Anthranilate phosphoribosyltransferase K00766 trpD; anthranilate phosphoribosyltransferase [EC:2.4.2.18] D spr1633 trpF; Phosphoribosylanthranilate isomerase K01817 trpF; phosphoribosylanthranilate isomerase [EC:5.3.1.24] D spr1634 trpC; Indole-3-glycerol-phosphate synthase K01609 trpC; indole-3-glycerol phosphate synthase [EC:4.1.1.48] D spr1631 trpA; Tryptophan synthase alpha chain K01695 trpA; tryptophan synthase alpha chain [EC:4.2.1.20] D spr1632 trpB; Tryptophan synthase beta chain K01696 trpB; tryptophan synthase beta chain [EC:4.2.1.20] D spr1174 Strong similarity to chorismate mutase; prephenate dehydratase K04516 AROA1; chorismate mutase [EC:5.4.99.5] D spr1231 tyrA; Prephenate dehydrogenase K04517 tyrA2; prephenate dehydrogenase [EC:1.3.1.12] D spr1227 pheA; Prephenate dehydratase K04518 pheA2; prephenate dehydratase [EC:4.2.1.51] B B 09106 Metabolism of other amino acids C 00410 beta-Alanine metabolism C 00430 Taurine and hypotaurine metabolism [PATH:spr00430] D spr1007 pta; Phosphate acetyltransferase K00625 pta; phosphate acetyltransferase [EC:2.3.1.8] D spr1854 ackA; Acetate kinase (acetokinase) K00925 ackA; acetate kinase [EC:2.7.2.1] C 00440 Phosphonate and phosphinate metabolism C 00450 Selenocompound metabolism [PATH:spr00450] D spr1377 metB; Cystathionine gamma-synthase K01739 metB; cystathionine gamma-synthase [EC:2.5.1.48] D spr1376 patB; Aminotransferase K14155 patB; cysteine-S-conjugate beta-lyase [EC:4.4.1.13] D spr0514 metE; Tetrahydropteroyltriglutamate methyltransferase K00549 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14] D spr0773 Conserved hypothetical protein K11717 sufS; cysteine desulfurase / selenocysteine lyase [EC:2.8.1.7 4.4.1.16] D spr1312 trxB; Thioredoxin reductase K00384 trxB; thioredoxin reductase (NADPH) [EC:1.8.1.9] D spr0696 metS; Methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] C 00460 Cyanoamino acid metabolism [PATH:spr00460] D spr1833 bgl2; Beta-glucosidase K05350 bglB; beta-glucosidase [EC:3.2.1.21] D spr1812 ansB; L-asparaginase (L-asparagine amidohydrolase) K01424 E3.5.1.1; L-asparaginase [EC:3.5.1.1] D spr1785 asnA; Aspartate--ammonia ligase (asparagine synthetase A) K01914 asnA; aspartate--ammonia ligase [EC:6.3.1.1] D spr0928 glyA; Serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] C 00470 D-Amino acid metabolism [PATH:spr00470] D spr1540 alr; Alanine racemase K01775 alr; alanine racemase [EC:5.1.1.1] D spr1515 ddl; D-alanine-D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4] D spr1982 dltA; D-alanine-D-alanyl carrier protein ligase K03367 dltA; D-alanine--poly(phosphoribitol) ligase subunit 1 [EC:6.1.1.13] D spr1980 dltC; D-alanyl carrier protein K14188 dltC; D-alanine--poly(phosphoribitol) ligase subunit 2 [EC:6.1.1.13] D spr1696 murI; Glutamate racemase K01776 murI; glutamate racemase [EC:5.1.1.3] D spr0603 murD; UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9] D spr1792 lysA; Diaminopimelate decarboxylase K01586 lysA; diaminopimelate decarboxylase [EC:4.1.1.20] C 00480 Glutathione metabolism [PATH:spr00480] D spr0706 pepN; Aminopeptidase N K01256 pepN; aminopeptidase N [EC:3.4.11.2] D spr0692 gor; Glutathione oxidoreductase K00383 GSR; glutathione reductase (NADPH) [EC:1.8.1.7] D spr0335 gnd; 6-phosphogluconate dehydrogenase K00033 PGD; 6-phosphogluconate dehydrogenase [EC:1.1.1.44 1.1.1.343] D spr1122 zwf; Glucose-6-phosphate 1-dehydrogenase K00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363] D spr0285 basA; Gluthatione peroxidase K00432 gpx; glutathione peroxidase [EC:1.11.1.9] D spr0819 speE; Spermidine synthase K00797 speE; spermidine synthase [EC:2.5.1.16] B B 09107 Glycan biosynthesis and metabolism C 00510 N-Glycan biosynthesis C 00513 Various types of N-glycan biosynthesis C 00512 Mucin type O-glycan biosynthesis C 00515 Mannose type O-glycan biosynthesis C 00514 Other types of O-glycan biosynthesis C 00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate C 00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin C 00533 Glycosaminoglycan biosynthesis - keratan sulfate C 00531 Glycosaminoglycan degradation C 00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis C 00601 Glycosphingolipid biosynthesis - lacto and neolacto series C 00603 Glycosphingolipid biosynthesis - globo and isoglobo series C 00604 Glycosphingolipid biosynthesis - ganglio series C 00511 Other glycan degradation [PATH:spr00511] D spr1531 nanB; Sialidase B precursor (neuraminidase B) K01186 NEU1; sialidase-1 [EC:3.2.1.18] D spr1536 nanA; Sialidase A precursor (neuraminidase A) K01186 NEU1; sialidase-1 [EC:3.2.1.18] D spr0565 bgaA; beta-galactosidase precursor K01190 lacZ; beta-galactosidase [EC:3.2.1.23] D spr0057 strH; Beta-N-acetyl-hexosaminidase precursor K12373 HEXA_B; hexosaminidase [EC:3.2.1.52] D spr1949 Hypothetical protein K12373 HEXA_B; hexosaminidase [EC:3.2.1.52] D spr1951 Conserved hypothetical protein K01191 MAN2C1; alpha-mannosidase [EC:3.2.1.24] D spr0867 lytB; Endo-beta-N-acetylglucosaminidase K23989 lytD; mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase [EC:3.2.1.96] D spr1954 Hypothetical protein K01206 FUCA; alpha-L-fucosidase [EC:3.2.1.51] D spr1498 Conserved hypothetical protein K15923 AXY8; alpha-L-fucosidase 2 [EC:3.2.1.51] D spr1966 Conserved hypothetical protein K15923 AXY8; alpha-L-fucosidase 2 [EC:3.2.1.51] C 00540 Lipopolysaccharide biosynthesis C 00542 O-Antigen repeat unit biosynthesis C 00541 O-Antigen nucleotide sugar biosynthesis [PATH:spr00541] D spr1903 galU; UTP-glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D spr1683 UDP-galactose 4-epimerase, truncation K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2] D spr1460 galE; UDP-glucose 4-epimerase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2] D spr1647 galE; UDP-glucose 4-epimerase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2] D spr0319 cps2P; The type 2 capsule locus of Streptococcus pneumoniae K01854 glf; UDP-galactopyranose mutase [EC:5.4.99.9] D spr0318 cps2K; The type 2 capsule locus of Streptococcus pneumoniae K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22] D spr0139 ugd; UDP-glucose dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22] D spr0320 cps2L; The type 2 capsule locus of Streptococcus pneumoniae K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24] D spr0322 cpsN; dTDP-glucose-4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46] D spr0321 cps2M; The type 2 capsule locus of Streptococcus pneumoniae K01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13] D spr0323 cpsO; dTDP-L-rhamnose synthase K00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133] D spr0647 pmi; Mannose-6-phosphate isomerase K01809 manA; mannose-6-phosphate isomerase [EC:5.3.1.8] D spr0891 gcaD; UDP-N-acetylglucosamine pyrophosphorylase K04042 glmU; bifunctional UDP-N-acetylglucosamine pyrophosphorylase / glucosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.3.1.157] D spr0092 capD; CapD protein, required for the biosynthesis of type 1 capsular polysaccharide K24300 wbpM; UDP-N-acetylglucosamine 4,6-dehydratase [EC:4.2.1.135] C 00550 Peptidoglycan biosynthesis [PATH:spr00550] D spr0989 murZ; UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7] D spr1781 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7] D spr1247 murB; UDP-N-acetylenolpyruvoylglucosamine reductase K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98] D spr1373 murC; UDP-N-acetylmuramate-alanine ligase K01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8] D spr0603 murD; UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9] D spr1515 ddl; D-alanine-D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4] D spr1514 murF; UDP-N-acetylmuramoylalanine-D-glutamyl-lysine-D-alanyl-D-alanine ligase K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10] D spr0870 dgkA; Diacylglycerol kinase K00887 dgkA; undecaprenol kinase [EC:2.7.1.66] D spr0240 uppS; Undecaprenyl diphosphate synthase K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31] D spr0413 bacA; A lipid kinase; may confer bacitracin resistance by phosphorylation of undecaprenol K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27] D spr0434 Conserved hypothetical protein K19302 bcrC; undecaprenyl-diphosphatase [EC:3.6.1.27] D spr0305 mraY; Undecaprenyl-phosphate-UDP-MurNAc-pentapeptide phospho-MurNAc-pentapeptide transferase K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13] D spr0604 murG; Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227] D spr0329 pbpA; Penicillin-binding protein 1A K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4] D spr1823 pbp2a; Penicillin-binding protein 2a K12555 pbp2A; penicillin-binding protein 2A [EC:2.4.99.28 3.4.16.4] D spr0776 dacA; D-alanyl-D-alanine carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] D spr0554 Conserved hypothetical protein K07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14] D spr1384 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine Ligase K05362 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-L-lysine ligase [EC:6.3.2.7] D spr1443 Conserved hypothetical protein K23393 murT; lipid II isoglutaminyl synthase (glutamine-hydrolysing) [EC:6.3.5.13] D spr1444 cobQ; Cobyric acid synthase K07009 gatD; lipid II isoglutaminyl synthase (glutamine-hydrolysing) [EC:6.3.5.13] D spr0540 murM; Serine/alanine adding enzyme K05363 murM; serine/alanine adding enzyme [EC:2.3.2.10] D spr0541 murN; Alanine adding enzyme K12554 murN; alanine adding enzyme [EC:2.3.2.-] D spr1909 pbp1b; Penicillin-binding protein 1b K03693 pbp1b; penicillin-binding protein 1B D spr1517 pbp2b; Penicillin-binding protein 2B K00687 pbp2B; penicillin-binding protein 2B D spr0304 pbpX; Penicillin-binding protein 2X K12556 pbp2X; penicillin-binding protein 2X C 00552 Teichoic acid biosynthesis [PATH:spr00552] D spr0413 bacA; A lipid kinase; may confer bacitracin resistance by phosphorylation of undecaprenol K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27] D spr0434 Conserved hypothetical protein K19302 bcrC; undecaprenyl-diphosphatase [EC:3.6.1.27] D spr1982 dltA; D-alanine-D-alanyl carrier protein ligase K03367 dltA; D-alanine--poly(phosphoribitol) ligase subunit 1 [EC:6.1.1.13] D spr1980 dltC; D-alanyl carrier protein K14188 dltC; D-alanine--poly(phosphoribitol) ligase subunit 2 [EC:6.1.1.13] D spr1981 dltB; D-alanine transfer from Dcp to undecaprenol-phosphate K03739 dltB; membrane protein involved in D-alanine export D spr1979 dltD; D-alanine transfer from undecaprenol-phosphate to the poly(glycerophosphate) chain K03740 dltD; D-alanine transfer protein D spr1226 Conserved hypothetical protein K01005 tagT_U_V; polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase [EC:2.7.8.-] D spr1759 lytR; Regulator of lytRABC operon K01005 tagT_U_V; polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase [EC:2.7.8.-] D spr0982 Conserved Hypothetical protein K19002 mgs; 1,2-diacylglycerol 3-alpha-glucosyltransferase [EC:2.4.1.337] D spr0981 cpoA; Glycosyltransferase K13678 cpoA; 1,2-diacylglycerol-3-alpha-glucose alpha-1,2-galactosyltransferase [EC:2.4.1.-] D spr0092 capD; CapD protein, required for the biosynthesis of type 1 capsular polysaccharide K24300 wbpM; UDP-N-acetylglucosamine 4,6-dehydratase [EC:4.2.1.135] D spr1654 Conserved hypothetical protein K25626 aatB; UDP-2-acetamido-4-dehydro-2,6-dideoxyglucose transaminase [EC:2.6.1.-] D spr1655 Conserved hypothetical protein K25627 wbgY; AATGal transferase D spr0091 Conserved hypothetical protein K25650 K25650; teichoic acid beta-1,3-glucosyltransferase [EC:2.4.1.-] D spr1225 licD1; LicD1 paralog K25651 licD3; teichoic acid ribitol-phosphate transferase D spr1223 cps23FU; Galactosyl transferase paralog K25652 K25652; teichoic acid N-acetylgalactosaminyltransferase [EC:2.4.1.-] D spr1224 Conserved hypothetical protein K25653 K25653; teichoic acid N-acetylgalactosaminyltransferase [EC:2.4.1.-] D spr1147 pck; Choline kinase K25657 licA; choline kinase [EC:2.7.1.32] D spr1145 licC; Homologous to LicC, which regulates expression of LPS epitopes in H. influenzae K25658 licC; choline-phosphate cytidylyltransferase [EC:2.7.7.15] D spr1151 licD1; Required for phosphorylcholine incorporation in teichoic and lipoteichoic acids K07271 licD; lipopolysaccharide cholinephosphotransferase [EC:2.7.8.-] D spr1152 licD2; licD Protein K25654 licD2; teichoic acid cholinephosphotransferase [EC:2.7.8.-] D spr1222 Hypothetical protein K25659 K25659; teichoic acid polymerase [EC:2.4.1.-] D spr1708 Hypothetical protein K25660 tacL; lipoteichoic acid ligase C 00571 Lipoarabinomannan (LAM) biosynthesis C 00572 Arabinogalactan biosynthesis - Mycobacterium C 00543 Exopolysaccharide biosynthesis [PATH:spr00543] D spr0517 cysE; Serine acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30] B B 09108 Metabolism of cofactors and vitamins C 00730 Thiamine metabolism [PATH:spr00730] D spr0638 thiD; Phosphomethylpyrimidine kinase K00941 thiD; hydroxymethylpyrimidine/phosphomethylpyrimidine kinase [EC:2.7.1.49 2.7.4.7] D spr0783 Probable pyridoxal-phosphate dependent aminotransferase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D spr1001 nifS; Pyridoxal-phosphate dependent aminotransferase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D spr0784 thiI; Thiamin biosynthesis protein K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4] D spr0629 thiM; Hydroxyethylthiazole kinase K00878 thiM; hydroxyethylthiazole kinase [EC:2.7.1.50] D spr0636 thiM; Hydroxyethylthiazole kinase K00878 thiM; hydroxyethylthiazole kinase [EC:2.7.1.50] D spr0630 thiE; Thiamin-phosphate pyrophosphorylase K00788 thiE; thiamine-phosphate pyrophosphorylase [EC:2.5.1.3] D spr0637 thiE; Thiamine phosphate pyrophosphorylase K00788 thiE; thiamine-phosphate pyrophosphorylase [EC:2.5.1.3] D spr1798 Conserved hypothetical protein K06949 rsgA; ribosome biogenesis GTPase / thiamine phosphate phosphatase [EC:3.6.1.- 3.1.3.100] D spr1796 Conserved hypothetical protein K00949 thiN; thiamine pyrophosphokinase [EC:2.7.6.2] D spr0210 adk; Adenylate kinase (ATP-AMP transphosphorylase) K00939 adk; adenylate kinase [EC:2.7.4.3] D spr0634 tenA; Transcriptional regulator of extracellular enzyme genes K03707 tenA; thiaminase (transcriptional activator TenA) [EC:3.5.99.2] D spr0628 Conserved hypothetical protein K03707 tenA; thiaminase (transcriptional activator TenA) [EC:3.5.99.2] C 00740 Riboflavin metabolism [PATH:spr00740] D spr0162 ribA; Riboflavin biosynthesis; GTP-cyclohydrolase II K14652 ribBA; 3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II [EC:4.1.99.12 3.5.4.25] D spr0164 ribD; Riboflavin biosynthese; a deaminase K11752 ribD; diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase [EC:3.5.4.26 1.1.1.193] D spr0263 Conserved hypothetical protein K21064 ycsE; 5-amino-6-(5-phospho-D-ribitylamino)uracil phosphatase [EC:3.1.3.104] D spr0161 ribE; Riboflavin synthase beta chain K00794 ribH; 6,7-dimethyl-8-ribityllumazine synthase [EC:2.5.1.78] D spr0163 ribC; Riboflavin synthase alpha-chain K00793 ribE; riboflavin synthase [EC:2.5.1.9] D spr1017 mreA; Macrolide-efflux protein K11753 ribF; riboflavin kinase / FMN adenylyltransferase [EC:2.7.1.26 2.7.7.2] D spr0629 thiM; Hydroxyethylthiazole kinase K00878 thiM; hydroxyethylthiazole kinase [EC:2.7.1.50] D spr0636 thiM; Hydroxyethylthiazole kinase K00878 thiM; hydroxyethylthiazole kinase [EC:2.7.1.50] D spr0892 Conserved hypothetical protein K01515 nudF; ADP-ribose diphosphatase [EC:3.6.1.13 3.6.1.-] C 00750 Vitamin B6 metabolism [PATH:spr00750] D spr1450 pdxK; Pyridoxine kinase K00868 pdxK; pyridoxine kinase [EC:2.7.1.35] D spr1878 thrC; Threonine synthase K01733 thrC; threonine synthase [EC:4.2.3.1] D spr1322 pdx1; Pyridoxine biosynthesis protein K06215 pdxS; pyridoxal 5'-phosphate synthase pdxS subunit [EC:4.3.3.6] D spr1321 Conserved hypothetical protein K08681 pdxT; pyridoxal 5'-phosphate synthase pdxT subunit [EC:4.3.3.6] C 00760 Nicotinate and nicotinamide metabolism [PATH:spr00760] D spr1829 nadC; Probable nicotinate-nucleotide pyrophosphorylase K00767 nadC; nicotinate-nucleotide pyrophosphorylase (carboxylating) [EC:2.4.2.19] D spr1277 Conserved hypothetical protein K00763 pncB; nicotinate phosphoribosyltransferase [EC:6.3.4.21] D spr0734 pnp; Purine nucleoside phosphorylase (inosine phosphorylase) K03783 punA; purine-nucleoside phosphorylase [EC:2.4.2.1] D spr0738 deoD; Purine nucleoside phosphorylase (inosine phosphorylase) K03784 deoD; purine-nucleoside phosphorylase [EC:2.4.2.1] D spr1592 Conserved hypothetical protein K00969 nadD; nicotinate-nucleotide adenylyltransferase [EC:2.7.7.18] D spr1276 nadE; NAD synthetase, ammonia dependent K01916 nadE; NAD+ synthase [EC:6.3.1.5] D spr1005 Conserved hypothetical protein K00858 ppnK; NAD+ kinase [EC:2.7.1.23] C 00770 Pantothenate and CoA biosynthesis [PATH:spr00770] D spr0401 ilvB; Acetolactate synthase large subunit K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] D spr0402 ilvN; Acetolactate synthase small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6] D spr0403 ilvC; Ketol-acid reductoisomerase K00053 ilvC; ketol-acid reductoisomerase [EC:1.1.1.86] D spr1935 ilvD; Dihydroxyacid dehydratase K01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9] D spr0741 coaA; Pantothenate kinase K00867 coaA; type I pantothenate kinase [EC:2.7.1.33] D spr1110 dfp_C-terminus; Similar to C-terminal region of the Dfp protein K21977 coaB; phosphopantothenate---cysteine ligase (CTP) [EC:6.3.2.5] D spr1111 dfp_N-terminus; Similar to N-terminal region of the Dfp protein K01598 PPCDC; phosphopantothenoylcysteine decarboxylase [EC:4.1.1.36] D spr1783 kdtB; lipopolysaccharide core biosynthesis protein K00954 E2.7.7.3A; pantetheine-phosphate adenylyltransferase [EC:2.7.7.3] D spr0873 Conserved hypothetical protein K00859 coaE; dephospho-CoA kinase [EC:2.7.1.24] D spr1541 acpS; Acyl Carrier protein synthase K00997 acpS; holo-[acyl-carrier protein] synthase [EC:2.7.8.7] D spr0758 ilvE; Branched-chain-amino-acid transaminase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] C 00780 Biotin metabolism [PATH:spr00780] D spr0382 fabF; Beta ketoacyl-acyl carrier protein synthase K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179] D spr0381 fabG; 3-ketoacyl-acyl carrier protein reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D spr0701 fabG; 3-Ketoacyl-ACP reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D spr0384 fabZ; Hydroxymyristoyl-(acyl carrier protein) dehydratase K02372 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59] D spr1715 birA; Biotin--[acetyl-CoA-carboxylase] ligase K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15] C 00785 Lipoic acid metabolism [PATH:spr00785] D spr1047 lplA; Lipoate protein ligase A K03800 lplA; lipoate---protein ligase [EC:6.3.1.20] D spr1048 acoL; Dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D spr1051 acoA; TPP-dependent acetoin dehydrogenase alpha chain K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1] D spr1050 acoB; TPP-dependent acetoin dehydrogenase beta chain K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1] D spr1049 acoC; Dihydrolipoamide S-acetyltransferase K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12] C 00790 Folate biosynthesis [PATH:spr00790] D spr0268 sulC; GTP cyclohydrolase K01495 GCH1; GTP cyclohydrolase IA [EC:3.5.4.16] D spr0269 sulD; Aldolase-pyrophosphokinase K13940 sulD; dihydroneopterin aldolase / 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase [EC:4.1.2.25 2.7.6.3] D spr0266 sulA; Dihydropteroate synthase K00796 folP; dihydropteroate synthase [EC:2.5.1.15] D spr1429 dfr; Dihydrofolate reductase K00287 DHFR; dihydrofolate reductase [EC:1.5.1.3] D spr0178 folC; Dihydrofolate:folylpolyglutamate synthetase K11754 folC; dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17] D spr0267 sulB; Dihydrofolate synthetase K11754 folC; dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17] D spr0162 ribA; Riboflavin biosynthesis; GTP-cyclohydrolase II K14652 ribBA; 3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II [EC:4.1.99.12 3.5.4.25] D spr0582 pabB; Para-aminobenzoate synthetase K03342 pabBC; para-aminobenzoate synthetase / 4-amino-4-deoxychorismate lyase [EC:2.6.1.85 4.1.3.38] D spr1603 Conserved hypothetical protein K09457 queF; 7-cyano-7-deazaguanine reductase [EC:1.7.1.13] C 00670 One carbon pool by folate [PATH:spr00670] D spr1429 dfr; Dihydrofolate reductase K00287 DHFR; dihydrofolate reductase [EC:1.5.1.3] D spr1109 fhs; Formate--tetrahydrofolate ligase K01938 fhs; formate--tetrahydrofolate ligase [EC:6.3.4.3] D spr0729 folD; Fold bifunctional protein; includes: methylenetetrahydrofolate dehydrogenase, methenyltetrahydrofolate cyclohydrolase K01491 folD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9] D spr0928 glyA; Serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D spr0049 purN; 5'-phosphoribosylglycinamide transformylase 1 K11175 purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2] D spr0051 purH; Phosphoribosylaminoimidazolecarboxamide formyltransferase K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10] D spr0585 thyA; Thymidylate synthase K00560 thyA; thymidylate synthase [EC:2.1.1.45] D spr0515 metF; 5,10-methylenetetrahydrofolate reductase K00297 metF; methylenetetrahydrofolate reductase (NADH) [EC:1.5.1.54] D spr1905 Conserved hypothetical protein K01934 MTHFS; 5-formyltetrahydrofolate cyclo-ligase [EC:6.3.3.2] D spr0671 metK; S-adenosylmethionine synthetase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6] D spr1048 acoL; Dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] C 00830 Retinol metabolism C 00860 Porphyrin metabolism [PATH:spr00860] D spr0914 hemH; Ferrochelatase K01772 hemH; protoporphyrin/coproporphyrin ferrochelatase [EC:4.98.1.1 4.99.1.9] C 00130 Ubiquinone and other terpenoid-quinone biosynthesis B B 09109 Metabolism of terpenoids and polyketides C 00900 Terpenoid backbone biosynthesis [PATH:spr00900] D spr1571 mvaS; 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) synthase K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10] D spr1570 mvaA; 3-hydroxy-3-methylglutaryl-coenzyme a reductase K00054 mvaA; hydroxymethylglutaryl-CoA reductase [EC:1.1.1.88] D spr0338 mvk; Mevalonate kinase K00869 MVK; mevalonate kinase [EC:2.7.1.36] D spr0340 mvaK2; Phosphomevalonate kinase K00938 E2.7.4.2; phosphomevalonate kinase [EC:2.7.4.2] D spr0339 mvd1; diphosphomevalonate decarboxylase K01597 MVD; diphosphomevalonate decarboxylase [EC:4.1.1.33] D spr0341 fni; Isopentenyl diphosphate isomerase K01823 idi; isopentenyl-diphosphate Delta-isomerase [EC:5.3.3.2] D spr1087 ispA; Farnesyl diphosphate synthase K13789 GGPS; geranylgeranyl diphosphate synthase, type II [EC:2.5.1.1 2.5.1.10 2.5.1.29] D spr0240 uppS; Undecaprenyl diphosphate synthase K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31] C 00902 Monoterpenoid biosynthesis C 00909 Sesquiterpenoid and triterpenoid biosynthesis C 00904 Diterpenoid biosynthesis C 00906 Carotenoid biosynthesis C 00905 Brassinosteroid biosynthesis C 00981 Insect hormone biosynthesis C 00908 Zeatin biosynthesis C 00903 Limonene degradation C 00907 Pinene, camphor and geraniol degradation C 01052 Type I polyketide structures C 00522 Biosynthesis of 12-, 14- and 16-membered macrolides C 01051 Biosynthesis of ansamycins D spr1841 tktA; Transketolase K00615 E2.2.1.1; transketolase [EC:2.2.1.1] D spr1936 tktC; Putative transketolase c-terminal section K00615 E2.2.1.1; transketolase [EC:2.2.1.1] D spr1937 tktN; Putative transketolase n-terminal section K00615 E2.2.1.1; transketolase [EC:2.2.1.1] C 01059 Biosynthesis of enediyne antibiotics C 01056 Biosynthesis of type II polyketide backbone C 01057 Biosynthesis of type II polyketide products C 00253 Tetracycline biosynthesis C 00523 Polyketide sugar unit biosynthesis [PATH:spr00523] D spr0320 cps2L; The type 2 capsule locus of Streptococcus pneumoniae K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24] D spr0322 cpsN; dTDP-glucose-4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46] D spr0321 cps2M; The type 2 capsule locus of Streptococcus pneumoniae K01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13] D spr0323 cpsO; dTDP-L-rhamnose synthase K00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133] C 01054 Nonribosomal peptide structures C 01053 Biosynthesis of siderophore group nonribosomal peptides C 01055 Biosynthesis of vancomycin group antibiotics D spr0322 cpsN; dTDP-glucose-4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46] B B 09110 Biosynthesis of other secondary metabolites C 00940 Phenylpropanoid biosynthesis C 00945 Stilbenoid, diarylheptanoid and gingerol biosynthesis C 00941 Flavonoid biosynthesis C 00944 Flavone and flavonol biosynthesis C 00942 Anthocyanin biosynthesis C 00943 Isoflavonoid biosynthesis C 00946 Degradation of flavonoids [PATH:spr00946] D spr1833 bgl2; Beta-glucosidase K05350 bglB; beta-glucosidase [EC:3.2.1.21] C 00901 Indole alkaloid biosynthesis C 00403 Indole diterpene alkaloid biosynthesis C 00950 Isoquinoline alkaloid biosynthesis C 00960 Tropane, piperidine and pyridine alkaloid biosynthesis C 00996 Biosynthesis of various alkaloids C 00232 Caffeine metabolism C 00965 Betalain biosynthesis C 00966 Glucosinolate biosynthesis C 00402 Benzoxazinoid biosynthesis C 00311 Penicillin and cephalosporin biosynthesis D spr1538 axe1; Xylan esterase 1 K01060 cah; cephalosporin-C deacetylase [EC:3.1.1.41] C 00332 Carbapenem biosynthesis [PATH:spr00332] D spr0832 proB; Gamma-glutamyl kinase K00931 proB; glutamate 5-kinase [EC:2.7.2.11] D spr0833 proA; Gamma-glutamyl phosphate reductase K00147 proA; glutamate-5-semialdehyde dehydrogenase [EC:1.2.1.41] C 00261 Monobactam biosynthesis [PATH:spr00261] D spr0374 lysC; Aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4] D spr0918 asd; Aspartate beta-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11] D spr0919 dapA; Dihydrodipicolinate synthase K01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7] D spr1414 dapB; Dihydrodipicolinate reductase K00215 dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8] C 00331 Clavulanic acid biosynthesis C 00521 Streptomycin biosynthesis [PATH:spr00521] D spr0584 glcK; Glucose kinase K25026 glk; glucokinase [EC:2.7.1.2] D spr1351 pgm; Phosphoglucomutase K01835 pgm; phosphoglucomutase [EC:5.4.2.2] D spr1260 Conserved hypothetical protein K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25] D spr0320 cps2L; The type 2 capsule locus of Streptococcus pneumoniae K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24] D spr0322 cpsN; dTDP-glucose-4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46] D spr0321 cps2M; The type 2 capsule locus of Streptococcus pneumoniae K01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13] D spr0323 cpsO; dTDP-L-rhamnose synthase K00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133] C 00524 Neomycin, kanamycin and gentamicin biosynthesis D spr0584 glcK; Glucose kinase K25026 glk; glucokinase [EC:2.7.1.2] C 00525 Acarbose and validamycin biosynthesis [PATH:spr00525] D spr0320 cps2L; The type 2 capsule locus of Streptococcus pneumoniae K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24] D spr0322 cpsN; dTDP-glucose-4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46] C 00401 Novobiocin biosynthesis D spr1231 tyrA; Prephenate dehydrogenase K04517 tyrA2; prephenate dehydrogenase [EC:1.3.1.12] C 00404 Staurosporine biosynthesis C 00405 Phenazine biosynthesis D spr1637 trpE; Anthranilate synthase component I K01657 trpE; anthranilate synthase component I [EC:4.1.3.27] D spr1636 trpG; Anthranilate synthase component II (glutamine amido-transferase) K01658 trpG; anthranilate synthase component II [EC:4.1.3.27] C 00333 Prodigiosin biosynthesis D spr0380 fabD; Malonyl acyl carrier protein transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39] D spr0381 fabG; 3-ketoacyl-acyl carrier protein reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D spr0701 fabG; 3-Ketoacyl-ACP reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] C 00254 Aflatoxin biosynthesis C 00998 Biosynthesis of various antibiotics D spr0038 acpP; Acyl carrier protein K02078 acpP; acyl carrier protein D spr0378 acp; Acyl carrier protein K02078 acpP; acyl carrier protein C 00999 Biosynthesis of various plant secondary metabolites [PATH:spr00999] D spr0671 metK; S-adenosylmethionine synthetase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6] D spr1833 bgl2; Beta-glucosidase K05350 bglB; beta-glucosidase [EC:3.2.1.21] C 00997 Biosynthesis of various other secondary metabolites B B 09111 Xenobiotics biodegradation and metabolism C 00362 Benzoate degradation [PATH:spr00362] D spr0066 Conserved hypothetical protein K07104 catE; catechol 2,3-dioxygenase [EC:1.13.11.2] D spr0921 xylH; 4-oxalocrotonate tautomerase K01821 praC; 4-oxalocrotonate tautomerase [EC:5.3.2.6] C 00627 Aminobenzoate degradation D spr1789 acyP; Acylphosphate phosphohydrolase K01512 acyP; acylphosphatase [EC:3.6.1.7] C 00364 Fluorobenzoate degradation C 00625 Chloroalkane and chloroalkene degradation [PATH:spr00625] D spr0262 adhP; Alcohol dehydrogenase, propanol-preferring K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1] D spr1837 adhE; Alcohol-acetaldehyde dehydrogenase K04072 adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1] C 00361 Chlorocyclohexane and chlorobenzene degradation D spr0066 Conserved hypothetical protein K07104 catE; catechol 2,3-dioxygenase [EC:1.13.11.2] C 00623 Toluene degradation C 00622 Xylene degradation [PATH:spr00622] D spr0066 Conserved hypothetical protein K07104 catE; catechol 2,3-dioxygenase [EC:1.13.11.2] D spr0921 xylH; 4-oxalocrotonate tautomerase K01821 praC; 4-oxalocrotonate tautomerase [EC:5.3.2.6] C 00633 Nitrotoluene degradation C 00642 Ethylbenzene degradation C 00643 Styrene degradation D spr0066 Conserved hypothetical protein K07104 catE; catechol 2,3-dioxygenase [EC:1.13.11.2] C 00791 Atrazine degradation C 00930 Caprolactam degradation C 00363 Bisphenol degradation C 00621 Dioxin degradation D spr0921 xylH; 4-oxalocrotonate tautomerase K01821 praC; 4-oxalocrotonate tautomerase [EC:5.3.2.6] C 00626 Naphthalene degradation [PATH:spr00626] D spr0262 adhP; Alcohol dehydrogenase, propanol-preferring K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1] D spr1837 adhE; Alcohol-acetaldehyde dehydrogenase K04072 adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1] C 00624 Polycyclic aromatic hydrocarbon degradation C 00365 Furfural degradation C 00984 Steroid degradation C 00980 Metabolism of xenobiotics by cytochrome P450 C 00982 Drug metabolism - cytochrome P450 C 00983 Drug metabolism - other enzymes B B 09112 Not included in regular maps C 09113 Global maps only # A09120 Genetic Information Processing B B 09121 Transcription C 03020 RNA polymerase [PATH:spr03020] D spr1777 rpoB; DNA-dependent RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6] D spr1776 rpoC; DNA-dependent RNA polymerase K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] D spr0215 rpoA; RNA polymerase alpha subunit K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6] D spr1582 Hypothetical protein K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6] D spr0437 rpoE; RNA polymerase (delta subunit) K03048 rpoE; DNA-directed RNA polymerase subunit delta C 03022 Basal transcription factors C 03040 Spliceosome B B 09122 Translation C 03010 Ribosome [PATH:spr03010] D spr0764 rpsA; 30S Ribosomal protein S1 K02945 RP-S1; small subunit ribosomal protein S1 D spr2020 rpsB; 30S Ribosomal protein S2 K02967 RP-S2; small subunit ribosomal protein S2 D spr0195 rpsC; 30S Ribosomal protein S3 K02982 RP-S3; small subunit ribosomal protein S3 D spr0078 rpsD; 30S Ribosomal protein S4 K02986 RP-S4; small subunit ribosomal protein S4 D spr0206 rpsE; 30S Ribosomal protein S5 K02988 RP-S5; small subunit ribosomal protein S5 D spr1396 rpsF; 30S Ribosomal protein S6 (S6) K02990 RP-S6; small subunit ribosomal protein S6 D spr0249 rpsG; 30S Ribosomal protein S7 K02992 RP-S7; small subunit ribosomal protein S7 D spr0203 rpsH; 30S Ribosomal protein S8 (S8) K02994 RP-S8; small subunit ribosomal protein S8 D spr0272 rpsI; 30S Ribosomal protein S9 K02996 RP-S9; small subunit ribosomal protein S9 D spr0187 rpsJ; 30S Ribosomal protein S10 K02946 RP-S10; small subunit ribosomal protein S10 D spr0214 rpsK; 30S Ribosomal protein S11 K02948 RP-S11; small subunit ribosomal protein S11 D spr0248 rpsL; 30S Ribosomal protein S12 K02950 RP-S12; small subunit ribosomal protein S12 D spr0213 rpsM; 30S Ribosomal protein S13 K02952 RP-S13; small subunit ribosomal protein S13 D spr0202 rpsN; 30S Ribosomal protein S14 K02954 RP-S14; small subunit ribosomal protein S14 D spr1467 rpsO; 30S Ribosomal protein S15 K02956 RP-S15; small subunit ribosomal protein S15 D spr0682 rpsP; 30S Ribosomal protein S16 K02959 RP-S16; small subunit ribosomal protein S16 D spr0198 rpsQ; 30S Ribosomal protein S17 K02961 RP-S17; small subunit ribosomal protein S17 D spr1394 rpsR; 30S Ribosomal protein S18 K02963 RP-S18; small subunit ribosomal protein S18 D spr0192 rpsS; 30S Ribosomal protein S19 K02965 RP-S19; small subunit ribosomal protein S19 D spr0740 rpsT; 30S Ribosomal protein subunit S20 K02968 RP-S20; small subunit ribosomal protein S20 D spr1271 rpsU; 30S Ribosomal protein S21 K02970 RP-S21; small subunit ribosomal protein S21 D spr0556 rplA; 50S Ribosomal protein L1 K02863 RP-L1; large subunit ribosomal protein L1 D spr0191 rplB; 50S Ribosomal protein L2 K02886 RP-L2; large subunit ribosomal protein L2 D spr0188 rplC; 50S Ribosomal protein L3 K02906 RP-L3; large subunit ribosomal protein L3 D spr0189 rplD; 50S Ribosomal protein L4 K02926 RP-L4; large subunit ribosomal protein L4 D spr0201 rplE; 50S Ribosomal protein L5 K02931 RP-L5; large subunit ribosomal protein L5 D spr0204 rplF; 50S Ribosomal protein L6 K02933 RP-L6; large subunit ribosomal protein L6 D spr1211 rplL; 50S Ribosomal protein L12 K02935 RP-L7; large subunit ribosomal protein L7/L12 D spr2009 rplI; 50S Ribosomal protein subunit L9 K02939 RP-L9; large subunit ribosomal protein L9 D spr1212 rplJ; 50S Ribosomal protein L10 K02864 RP-L10; large subunit ribosomal protein L10 D spr0555 rplK; 50S Ribosomal protein L11 K02867 RP-L11; large subunit ribosomal protein L11 D spr0271 rplM; 50S Ribosomal protein L13 K02871 RP-L13; large subunit ribosomal protein L13 D spr0199 rplN; 50S Ribosomal protein L14 K02874 RP-L14; large subunit ribosomal protein L14 D spr0208 rplO; 50S Ribosomal protein L15 K02876 RP-L15; large subunit ribosomal protein L15 D spr0196 rplP; 50S Ribosomal protein L16 K02878 RP-L16; large subunit ribosomal protein L16 D spr0216 rplQ; 50S Ribosomal protein L17 K02879 RP-L17; large subunit ribosomal protein L17 D spr0205 rplR; 50S Ribosomal protein L18 K02881 RP-L18; large subunit ribosomal protein L18 D spr1171 rplS; 50S Ribosomal protein L19 K02884 RP-L19; large subunit ribosomal protein L19 D spr0863 rplT; 50S Ribosomal protein L20 K02887 RP-L20; large subunit ribosomal protein L20 D spr1012 rplU; 50S Ribosomal protein L21 K02888 RP-L21; large subunit ribosomal protein L21 D spr0194 rplV; 50S Ribosomal protein L22 K02890 RP-L22; large subunit ribosomal protein L22 D spr0190 rplW; 50S Ribosomal protein L23 K02892 RP-L23; large subunit ribosomal protein L23 D spr0200 rplX; 50S Ribosomal protein L24 K02895 RP-L24; large subunit ribosomal protein L24 D spr1014 rpmA; 50S Ribosomal protein L27 K02899 RP-L27; large subunit ribosomal protein L27 D spr0398 rpmB; 50S Ribosomal protein L28 K02902 RP-L28; large subunit ribosomal protein L28 D spr0197 rpmC; 50S Ribosomal protein L29 K02904 RP-L29; large subunit ribosomal protein L29 D spr0207 rpmD; 50S Ribosomal protein L30 K02907 RP-L30; large subunit ribosomal protein L30 D spr1177 rpmE; 50S ribosomal protein L31 K02909 RP-L31; large subunit ribosomal protein L31 D spr1943 rpmF; 50S Ribosomal protein L32 K02911 RP-L32; large subunit ribosomal protein L32 D spr0876 rpmG; 50S Ribosomal protein L33 K02913 RP-L33; large subunit ribosomal protein L33 D spr1822 rpmG; 50S Ribosomal protein L33 K02913 RP-L33; large subunit ribosomal protein L33 D spr1944 rpmG; 50S Ribosomal protein L33 K02913 RP-L33; large subunit ribosomal protein L33 D spr1807 rpmH; 50S Ribosomal protein L34 K02914 RP-L34; large subunit ribosomal protein L34 D spr0862 rpmI; 50S Ribosomal protein L35 K02916 RP-L35; large subunit ribosomal protein L35 D spr0212 rpmJ; 50S Ribosomal protein L36 K02919 RP-L36; large subunit ribosomal protein L36 D sprr01 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D sprr06 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D sprr09 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D sprr12 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D sprr02 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D sprr05 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D sprr08 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D sprr11 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D sprr03 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D sprr04 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D sprr07 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D sprr10 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA C 00970 Aminoacyl-tRNA biosynthesis [PATH:spr00970] D sprt02 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D sprt54 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D sprt41 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D sprt29 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D sprt08 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D sprt58 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D sprt09 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D sprt21 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D sprt33 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D sprt03 tRNA-Asn K14220 tRNA-Asn; tRNA Asn D sprt56 tRNA-Asn K14220 tRNA-Asn; tRNA Asn D sprt27 tRNA-Asp K14221 tRNA-Asp; tRNA Asp D sprt39 tRNA-Asp K14221 tRNA-Asp; tRNA Asp D sprt31 tRNA-Cys K14222 tRNA-Cys; tRNA Cys D sprt05 tRNA-Gln K14223 tRNA-Gln; tRNA Gln D sprt44 tRNA-Gln K14223 tRNA-Gln; tRNA Gln D sprt01 tRNA-Glu K14224 tRNA-Glu; tRNA Glu D sprt57 tRNA-Glu K14224 tRNA-Glu; tRNA Glu D sprt42 tRNA-Glu K14224 tRNA-Glu; tRNA Glu D sprt55 tRNA-Glu K14224 tRNA-Glu; tRNA Glu D sprt30 tRNA-Glu K14224 tRNA-Glu; tRNA Glu D sprt14 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D sprt52 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D sprt23 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D sprt35 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D sprt45 tRNA-His K14226 tRNA-His; tRNA His D sprt13 tRNA-Ile K14227 tRNA-Ile; tRNA Ile D sprt51 tRNA-Ile K14227 tRNA-Ile; tRNA Ile D sprt22 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D sprt34 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D sprt43 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D sprt25 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D sprt37 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D sprt10 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D sprt26 tRNA-Lys K14229 tRNA-Lys; tRNA Lys D sprt38 tRNA-Lys K14229 tRNA-Lys; tRNA Lys D sprt11 tRNA-Lys K14229 tRNA-Lys; tRNA Lys D sprt19 tRNA-Met K14230 tRNA-Met; tRNA Met D sprt18 tRNA-Met K14230 tRNA-Met; tRNA Met D sprt16 tRNA-Met K14230 tRNA-Met; tRNA Met D sprt49 tRNA-Met K14230 tRNA-Met; tRNA Met D sprt15 tRNA-Phe K14231 tRNA-Phe; tRNA Phe D sprt48 tRNA-Phe K14231 tRNA-Phe; tRNA Phe D sprt20 tRNA-Pro K14232 tRNA-Pro; tRNA Pro D sprt32 tRNA-Pro K14232 tRNA-Pro; tRNA Pro D sprt17 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D sprt50 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D sprt12 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D sprt06 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D sprt07 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D sprt24 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D sprt36 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D sprt46 tRNA-Trp K14235 tRNA-Trp; tRNA Trp D sprt47 tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr D sprt04 tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr D sprt28 tRNA-Val K14237 tRNA-Val; tRNA Val D sprt40 tRNA-Val K14237 tRNA-Val; tRNA Val D sprt53 tRNA-Val K14237 tRNA-Val; tRNA Val D spr1881 gltX; Glutamyl-tRNA synthetase (glutamate--tRNA ligase) K09698 gltX; nondiscriminating glutamyl-tRNA synthetase [EC:6.1.1.24] D spr0394 gatA; Glu-tRNAGln amidotransferase subunit A K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7] D spr0393 gatB; Glutamyl tRNA-Gln amidotransferase subunit B K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7] D spr0395 gatC; Glutamyl tRNA-Gln amidotransferase, subunit C K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7] D spr1240 alaS; Alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7] D spr1924 aspS; Aspartyl-tRNA synthetase (aspartate-tRNA ligase) K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12] D spr1397 asnS; Asparaginyl-tRNA synthetase (asparagine--tRNA ligase) K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22] D spr1329 glyQ; Glycyl-tRNA synthetase alpha chain K01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14] D spr1328 glyS; Glycyl-tRNA synthetase beta chain K01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14] D spr1472 thrS; Threonyl-tRNA synthetase 1 K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3] D spr0372 serS; Seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11] D spr0519 cysS; Cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16] D spr0696 metS; Methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] D spr1580 fmt; Methionyl-tRNA formyltransferase K00604 MTFMT; methionyl-tRNA formyltransferase [EC:2.1.2.9] D spr0492 valS; Valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9] D spr0235 leuS; Leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D spr1502 ileS; Isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5] D spr0626 lysS; Lysyl-tRNA synthetase (lysine--tRNA ligase) (LYSRS) K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6] D spr1890 argS; Arginyl-tRNA synthetase(arginine--tRNA ligase) (ARGRS) K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D spr0243 proS; Prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15] D spr1931 hisS; Histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21] D spr0507 pheS; Phenylalanyl-tRNA synthetase alpha chain K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20] D spr0509 pheT; Phenylalanyl-tRNA synthetase beta chain K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20] D spr1910 tyrS; Tyrosyl-tRNA synthetase 1 K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D spr2034 trpS; Tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2] C 03013 Nucleocytoplasmic transport C 03015 mRNA surveillance pathway C 03008 Ribosome biogenesis in eukaryotes B B 09123 Folding, sorting and degradation C 03060 Protein export [PATH:spr03060] D spr0209 secY; Multispanning membrane protein, translocator of proteins K03076 secY; preprotein translocase subunit SecY D spr1821 secE; Preprotein translocase secE component K03073 secE; preprotein translocase subunit SecE D spr0877 secG; Protein-export membrane protein secG K03075 secG; preprotein translocase subunit SecG D spr1840 Conserved hypothetical protein K03210 yajC; preprotein translocase subunit YajC D spr0296 Conserved hypothetical protein K03210 yajC; preprotein translocase subunit YajC D spr1852 Conserved hypothetical protein K03217 yidC; YidC/Oxa1 family membrane protein insertase D spr1790 Conserved hypothetical protein K03217 yidC; YidC/Oxa1 family membrane protein insertase D spr1544 secA; Preprotein translocase secA subunit K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8] D spr1166 ffh; Signal recognition particle (Fifty four homolog) K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4] D sprs01 scRNA; scRNA K01983 ffs; SRP RNA D spr1123 ftsY; Cell division protein FtsY K03110 ftsY; fused signal recognition particle receptor D spr0364 spi; Signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89] D spr0829 lspA; Signal peptidase type II; lipoprotein signal peptidase K03101 lspA; signal peptidase II [EC:3.4.23.36] C 04141 Protein processing in endoplasmic reticulum C 04130 SNARE interactions in vesicular transport C 04120 Ubiquitin mediated proteolysis C 04122 Sulfur relay system [PATH:spr04122] D spr0783 Probable pyridoxal-phosphate dependent aminotransferase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D spr1001 nifS; Pyridoxal-phosphate dependent aminotransferase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D spr0122 trmU; tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13] D spr0784 thiI; Thiamin biosynthesis protein K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4] C 03050 Proteasome C 03018 RNA degradation [PATH:spr03018] D spr1036 eno; Enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D spr0516 pnpA; Polyribonucleotide nucleotidyltransferase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] D spr0878 rnr; Exoribonuclease R K12573 rnr; ribonuclease R [EC:3.1.13.1] D spr1440 Conserved hypothetical protein K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7] D spr1584 Conserved hypothetical protein K18682 rny; ribonucrease Y [EC:3.1.-.-] D spr0125 Conserved hypothetical protein K12574 rnj; ribonuclease J [EC:3.1.-.-] D spr0538 Conserved hypothetical protein K12574 rnj; ribonuclease J [EC:3.1.-.-] D spr0796 pfkA; 6-phosphofructokinase I K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] D spr0455 dnaK; Class I heat-shock protein (molecular chaperone) K04043 dnaK; molecular chaperone DnaK D spr1722 groEL; Chaperonin GroEL K04077 groEL; chaperonin GroEL [EC:5.6.1.7] B B 09124 Replication and repair C 03030 DNA replication [PATH:spr03030] D spr0896 dnaQ; DNA polymerase III, epsilon chain K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] D spr0795 dnaE; DNA-polymerase III alpha-chain K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] D spr0251 polC; DNA polymerase III, alpha subunit K03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7] D spr0769 dnaX; DNA-directed DNA polymerase III chain K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D spr0836 holB; DNA polymerase III, delta' subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7] D spr0673 holA; DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] D spr0002 dnaN; DNA biosynthesis; sliding clamp subunit, required for high processivity; DNA polymerase III beta-subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] D spr2008 dnaC; Replicative DNA helicase K02314 dnaB; replicative DNA helicase [EC:5.6.2.3] D spr0978 dnaG; DNA primase K02316 dnaG; DNA primase [EC:2.7.7.101] D spr1395 ssbA; Single stranded binding protein K03111 ssb; single-strand DNA-binding protein D spr1724 ssbB; Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein D spr1044 rnh; Ribonuclease H K03470 rnhB; ribonuclease HII [EC:3.1.26.4] D spr0365 rnhB; Ribonuclease HII K03471 rnhC; ribonuclease HIII [EC:3.1.26.4] D spr0032 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] D spr1024 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] C 03410 Base excision repair [PATH:spr03410] D spr1157 nth; endonuclease III (DNA repair) K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] D spr1055 ung; DNA-uracil glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27] D spr1108 mutY; Similar to A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31] D spr0872 mutM; Formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18] D spr0166 tag; 3-Methyladenine DNA glycosylase I, constitutive K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20] D spr1660 exoA; Exodeoxyribonuclease K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2] D spr0032 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] D spr0537 recJ; Single-stranded DNA-specific exonuclease, 5'-3' K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D spr1024 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] C 03420 Nucleotide excision repair [PATH:spr03420] D spr0006 mfd; Transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4] D spr0171 uvrA; Excinuclease ABC - subunit A K03701 uvrA; excinuclease ABC subunit A D spr1118 uvrB; Exonuclease ABC - subunit B K03702 uvrB; excinuclease ABC subunit B D spr0543 uvrC; Exonuclease ABC - subunit C K03703 uvrC; excinuclease ABC subunit C D spr0995 pcrA; ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] D spr0032 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] D spr1024 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] C 03430 Mismatch repair [PATH:spr03430] D spr1888 hexA; DNA mismatch repair protein HexA K03555 mutS; DNA mismatch repair protein MutS D spr0368 mutS2; DNA mismatch repair protein K07456 mutS2; DNA mismatch repair protein MutS2 D spr0160 hexB; DNA mismatch repair protein K03572 mutL; DNA mismatch repair protein MutL D spr0995 pcrA; ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] D spr1089 xseA; Exodeoxyribonuclease large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6] D spr1088 xseB; Exodeoxyribonuclease small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6] D spr0537 recJ; Single-stranded DNA-specific exonuclease, 5'-3' K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D spr1395 ssbA; Single stranded binding protein K03111 ssb; single-strand DNA-binding protein D spr1724 ssbB; Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein D spr0795 dnaE; DNA-polymerase III alpha-chain K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] D spr0251 polC; DNA polymerase III, alpha subunit K03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7] D spr0002 dnaN; DNA biosynthesis; sliding clamp subunit, required for high processivity; DNA polymerase III beta-subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] D spr0769 dnaX; DNA-directed DNA polymerase III chain K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D spr0673 holA; DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] D spr0836 holB; DNA polymerase III, delta' subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7] D spr0896 dnaQ; DNA polymerase III, epsilon chain K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] D spr1024 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] C 03440 Homologous recombination [PATH:spr03440] D spr0537 recJ; Single-stranded DNA-specific exonuclease, 5'-3' K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D spr1395 ssbA; Single stranded binding protein K03111 ssb; single-strand DNA-binding protein D spr1724 ssbB; Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein D spr2032 recF; Recombination protein RecF K03629 recF; DNA replication and repair protein RecF D spr0036 Conserved hypothetical protein K03584 recO; DNA repair protein RecO (recombination protein O) D spr1516 recR; Recombination protein RecR K06187 recR; recombination protein RecR D spr1757 recA; DNA recombination/repair K03553 recA; recombination protein RecA D spr0032 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] D spr0165 ruvA; Holliday junction DNA helicase K03550 ruvA; holliday junction DNA helicase RuvA D spr0238 ruvB; Branch migration of Holliday structures K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4] D spr1539 recG; Branch migration of Holliday junctions, junction-specific DNA helicase K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4] D spr0363 recD; Exonuclease V K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5] D spr0795 dnaE; DNA-polymerase III alpha-chain K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] D spr0251 polC; DNA polymerase III, alpha subunit K03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7] D spr0002 dnaN; DNA biosynthesis; sliding clamp subunit, required for high processivity; DNA polymerase III beta-subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] D spr0769 dnaX; DNA-directed DNA polymerase III chain K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D spr0673 holA; DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] D spr0836 holB; DNA polymerase III, delta' subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7] D spr0896 dnaQ; DNA polymerase III, epsilon chain K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] D spr1581 priA; Primosomal replication factor Y K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4] C 03450 Non-homologous end-joining C 03460 Fanconi anemia pathway B B 09126 Chromosome C 03082 ATP-dependent chromatin remodeling C 03083 Polycomb repressive complex B B 09125 Information processing in viruses C 03230 Viral genome structure C 03240 Viral replication C 03250 Viral life cycle - HIV-1 [PATH:spr03250] D spr0679 ppiA; Peptidyl-prolyl cis-trans isomerase K03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8] C 03260 Virion - Human immunodeficiency virus C 03271 Virion - Rotavirus C 03262 Virion - Coronavirus C 03261 Virion - Influenza virus C 03263 Virion - Enterovirus C 03264 Virion - Flavivirus and Alphavirus C 03265 Virion - Ebolavirus, Lyssavirus and Morbillivirus C 03272 Virion - Hepatitis viruses C 03266 Virion - Herpesvirus C 03268 Virion - Orthopoxvirus C 03267 Virion - Adenovirus C 03259 Virion - Bacteriophages T4 and T7 C 03258 Virion - Bacteriophage lambda # A09130 Environmental Information Processing B B 09131 Membrane transport C 02010 ABC transporters [PATH:spr02010] D spr1645 ABC-SBP; ABC transporter substrate-binding protein - unknown substrate K02012 afuA; iron(III) transport system substrate-binding protein D spr1643 ABC-MSP; ABC transporter membrane-spanning permease - unknown substrate K02011 afuB; iron(III) transport system permease protein D spr0220 ABC-MSP; ABC transporter membrane-spanning permease - iron transport K02011 afuB; iron(III) transport system permease protein D spr0221 ABC-MSP; ABC transporter membrane-spanning permease - iron transport K02011 afuB; iron(III) transport system permease protein D spr1644 ABC-NBD; ABC transporter ATP-binding protein - unknown substrate K02010 afuC; iron(III) transport system ATP-binding protein [EC:7.2.2.7] D spr0222 ABC-NBD; ABC transporter ATP-binding protein - iron transport K02010 afuC; iron(III) transport system ATP-binding protein [EC:7.2.2.7] D spr1243 potD; ABC transporter substrate-binding protein - spermidine/putrescine transport K11069 potD; spermidine/putrescine transport system substrate-binding protein D spr1244 potC; ABC transporter membrane-spanning permease - spermidine/putrescine transport K11070 potC; spermidine/putrescine transport system permease protein D spr1245 potB; ABC transporter membrane-spanning permease - spermidine/putrescine transport K11071 potB; spermidine/putrescine transport system permease protein D spr1246 potA; ABC transporter ATP-binding protein - spermidine/putrescine transport K11072 potA; spermidine/putrescine transport system ATP-binding protein [EC:7.6.2.11] D spr1677 proWX; ABC transporter membrane-spanning permease - choline transporter K05845 opuC; osmoprotectant transport system substrate-binding protein D spr1678 proV; ABC transporter ATP-binding protein - choline transporter K05847 opuA; osmoprotectant transport system ATP-binding protein [EC:7.6.2.9] D spr1437 msmK; ABC transporter ATP-binding protein - multiple sugar transport K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-] D spr1918 malX; ABC transporter substrate-binding protein - maltose/maltodextrin K15770 cycB; arabinogalactan oligomer / maltooligosaccharide transport system substrate-binding protein D spr1919 malC; ABC transporter membrane-spanning permease - maltose/maltodextrin K15771 ganP; arabinogalactan oligomer / maltooligosaccharide transport system permease protein D spr1920 malD; ABC transporter membrane-spanning permease - maltose/maltodextrin K15772 ganQ; arabinogalactan oligomer / maltooligosaccharide transport system permease protein D spr1712 msmE; ABC transporter substrate-binding protein - multiple sugars K10117 msmE; raffinose/stachyose/melibiose transport system substrate-binding protein D spr1711 msmF; ABC transporter membrane-spanning permease - multiple sugars K10118 msmF; raffinose/stachyose/melibiose transport system permease protein D spr1710 msmG; ABC transporter membrane spanning permease - multiple sugars K10119 msmG; raffinose/stachyose/melibiose transport system permease protein D spr0083 ABC-SBP; ABC transporter solute binding protein - sugar transport K17318 lplA; putative aldouronate transport system substrate-binding protein D spr0081 ABC-MSP; ABC transporter membrane-spanning permease - sugar transport K17319 lplB; putative aldouronate transport system permease protein D spr0082 ABC-MSP; ABC transporter membrane spanning permease - sugar transport K17320 lplC; putative aldouronate transport system permease protein D spr0747 Conserved hypothetical protein K07335 bmpA; basic membrane protein A and related proteins D spr0749 ABC-MSP; ABC transporter membrane-spanning permease - ribose/galactose transport K23535 nupB; general nucleoside transport system permease protein D spr0750 ABC-MSP; ABC transporter membrane-spanning permease - ribose/galactose transport K23536 nupC; general nucleoside transport system permease protein D spr0748 ABC-NBD; ABC transporter ATP-binding protein - ribose/galactose transport K23537 nupA; general nucleoside transport system ATP-binding protein D spr1257 pstS; ABC transporter substrate-binding protein - phosphate transport K02040 pstS; phosphate transport system substrate-binding protein D spr1895 pstS; ABC transporter substrate-binding protein - phosphate transport K02040 pstS; phosphate transport system substrate-binding protein D spr1256 pstC; ABC transporter membrane-spanning permease - phosphate transport K02037 pstC; phosphate transport system permease protein D spr1896 pstC; ABC transporter membrane-spanning permease - phosphate transport K02037 pstC; phosphate transport system permease protein D spr1255 pstA; ABC transporter membrane-spanning permease - phosphate transport K02038 pstA; phosphate transport system permease protein D spr1897 pstA; ABC transporter membrane-spanning permease - phosphate transport K02038 pstA; phosphate transport system permease protein D spr1253 pstB; ABC transporter ATP-binding protein - phosphate transport K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1] D spr1254 pstB; ABC transporter ATP-binding protein - phosphate transport K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1] D spr1898 pstB; ABC transporter ATP-binding protein - phosphate transport K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1] D spr1120 glnP; ABC transporter membrane spanning permease - glutamine transport K10036 glnH; glutamine transport system substrate-binding protein D spr1121 glnQ; ABC transporter ATP-binding protein - glutamine transport K10038 glnQ; glutamine transport system ATP-binding protein [EC:7.4.2.1] D spr0534 glnH; ABC transporter substrate-binding protein - glutamine transport/Major cell binding factor precursor K10039 peb1A; aspartate/glutamate/glutamine transport system substrate-binding protein D spr0533 glnP; ABC transporter membrane-spanning permease - glutamine transport K10040 peb1B; aspartate/glutamate/glutamine transport system permease protein D spr0532 glnP; ABC transporter membrane-spanning permease - glutamine transport K10040 peb1B; aspartate/glutamate/glutamine transport system permease protein D spr0146 ABC-SBP; ABC transporter substrate-binding protein - amino acid transport K02424 tcyA; L-cystine transport system substrate-binding protein D spr1315 ABC-MSP; ABC transporter membrane-spanning permease - aspartate/glutamate transport K10009 tcyB; L-cystine transport system permease protein D spr1314 ABC-NDB; ABC transporter ATP-binding protein - aspartate/glutamate transport K10010 tcyC; L-cystine transport system ATP-binding protein [EC:7.4.2.1] D spr1251 glnH; ABC transporter substrate-binding protein - glutamine-binding protein K23059 artP; arginine/lysine/histidine transporter system substrate-binding protein D spr0727 glnP; ABC transporter membrane-spanning permease - glutamine transport K17077 artQ; arginine/lysine/histidine transport system permease protein D spr0728 glnQ; ABC transporter ATP-binding protein - glutamine transport K23060 artR; arginine/lysine/histidine transport system ATP-binding protein [EC:7.4.2.1] D spr0409 glnH; ABC transporter substrate binding protein - glutamine transport K17073 lysX1; putative lysine transport system substrate-binding protein D spr0408 glnQ; ABC transporter ATP-binding protein - glutamine K17076 lysY; putative lysine transport system ATP-binding protein D spr0659 livJ; ABC transporter substrate-binding protein - branched chain amino acid transport K01999 livK; branched-chain amino acid transport system substrate-binding protein D spr0660 livH; ABC transporter membrane-spanning permease - branched chain amino acid transport K01997 livH; branched-chain amino acid transport system permease protein D spr0661 livM; ABC transporter membrane-spanning permease - branched chain amino acid transport K01998 livM; branched-chain amino acid transport system permease protein D spr0662 livG; ABC transporter ATP-binding protein - branched chain amino acid transport K01995 livG; branched-chain amino acid transport system ATP-binding protein D spr0663 livF; ABC transporter ATP-binding protein - branched chain amino acid transport K01996 livF; branched-chain amino acid transport system ATP-binding protein D spr0147 ABC-SBP; ABC transporter solute-binding protein - unknown substrate K02073 metQ; D-methionine transport system substrate-binding protein D spr0150 ABC-MSD; ABC transporter membrane-spanning permease - unknown substrate K02072 metI; D-methionine transport system permease protein D spr0149 ABC-NBD; ABC transporter ATP-binding protein - unknown substrate K02071 metN; D-methionine transport system ATP-binding protein D spr1382 aliB; ABC transporter substrate-binding protein - oligopeptide transport K15580 oppA; oligopeptide transport system substrate-binding protein D spr1707 amiA; ABC transporter substrate-binding protein - oligopeptide transport K15580 oppA; oligopeptide transport system substrate-binding protein D spr1706 amiC; ABC transporter membrane-spanning permease - oligopeptide transport K15581 oppB; oligopeptide transport system permease protein D spr1705 amiD; ABC transporter membrane-spanning permease - oligopeptide transport K15582 oppC; oligopeptide transport system permease protein D spr1704 amiE; ABC transporter ATP-binding protein - oligopeptide transport K15583 oppD; oligopeptide transport system ATP-binding protein D spr1703 amiF; ABC transporter ATP-binding protein - oligopeptide transport K10823 oppF; oligopeptide transport system ATP-binding protein D spr0934 ABC-SBP; ABC transporter substrate-binding protein - iron transport K25286 fagD; iron-siderophore transport system substrate-binding protein D spr0935 ABC-MSP; ABC transporter membrane-spanning permease - iron transport K23186 fepD; iron-siderophore transport system permease protein D spr0936 ABC-MSP; ABC transporter membrane-spanning permease - iron transport K23187 fepG; iron-siderophore transport system permease protein D spr0938 ABC-NBD; ABC transporter ATP-binding protein - iron transport K23188 fepC; iron-siderophore transport system ATP-binding protein [EC:7.2.2.17 7.2.2.-] D spr0906 lmb; Lipoprotein K09815 znuA; zinc transport system substrate-binding protein D spr1975 adcA; ABC transporter substrate-binding protein - Zinc (Zn2+) transport K09815 znuA; zinc transport system substrate-binding protein D spr1976 adcB; ABC transporter membrane-spanning permease - Zinc (Zn2+) transport K09816 znuB; zinc transport system permease protein D spr1977 adcC; ABC transporter ATP-binding domain - Zinc (Zn2+) permease K09817 znuC; zinc transport system ATP-binding protein [EC:7.2.2.20] D spr1494 psaA; ABC transporter substrate-binding protein - manganese transport K19971 psaA; manganese/zinc transport system substrate-binding protein D spr1493 psaC; ABC transporter membrane-spanning permease - manganese transport K19972 psaC; manganese/zinc transport system permease protein D spr1492 psaB; ABC transporter ATP-binding protein - manganese transport K10830 psaB; manganese/zinc transport system ATP-binding protein [EC:7.2.2.5] D spr0691 bioY; Biotin synthase K03523 bioY; biotin transport system substrate-specific component D spr0431 ABC-MSD; ABC transporter membrane-spanning permease - unknown substrate K16785 ecfT; energy-coupling factor transport system permease protein D spr2024 ABC-MSP; ABC transporter membrane-spanning permease - unknown substrate K16785 ecfT; energy-coupling factor transport system permease protein D spr0633 Conserved hypothetical protein K16785 ecfT; energy-coupling factor transport system permease protein D spr1292 Conserved hypothetical protein K16785 ecfT; energy-coupling factor transport system permease protein D spr2026 stpA; ABC transporter ATP-binding protein - unknown substrate K16786 ecfA1; energy-coupling factor transport system ATP-binding protein [EC:7.-.-.-] D spr2025 ABC-NBP; ABC transporter ATP-binding protein - unknown substrate K16787 ecfA2; energy-coupling factor transport system ATP-binding protein [EC:7.-.-.-] D spr0813 ABC-MSD; ABC transporter membrane-spanning permease - unknown substrate K19084 braE; bacitracin transport system permease protein D spr0812 ABC-NBD; ABC transporter ATP-binding protein - unknown substrate K19083 braD; bacitracin transport system ATP-binding protein D spr0667 ftsX; Cell division protein FtsX K09811 ftsX; cell division transport system permease protein D spr0666 ftsE; ABC transporter ATP-binding protein & cell division protein K09812 ftsE; cell division transport system ATP-binding protein D spr1289 ABC-N_P; ABC transporter ATP-binding/membrane-spanning protein - unknown substrate K14698 irtA; ATP-binding cassette, subfamily B, bacterial IrtA/YbtP [EC:7.-.-.-] D spr1290 ABC-N_P; ABC transporter ATP-binding/membrane-spanning protein - unknown substrate K14699 irtB; ATP-binding cassette, subfamily B, bacterial IrtB/YbtQ [EC:7.-.-.-] D spr1657 ABC-N_P; ABC transporter ATP-binding/membrane spanning protein - unknown substrate K18889 mdlA; ATP-binding cassette, subfamily B, multidrug efflux pump D spr1656 ABC-N_P; ABC transporter ATP-binding/membrane spanning protein - unknown substrate K18890 mdlB; ATP-binding cassette, subfamily B, multidrug efflux pump D spr1887 ABC-NP; ABC transporter ATP-binding/membrane spanning protein - unknown substrate K18891 patA; ATP-binding cassette, subfamily B, multidrug efflux pump D spr1885 ABC-NP; ABC transporter ATP-binding/membrane spanning protein - unknown substrate K18892 patB; ATP-binding cassette, subfamily B, multidrug efflux pump D spr1216 ABC-N_P; ABC transporter ATP-binding/membrane-spanning protein - unknown substrate K18887 efrA; ATP-binding cassette, subfamily B, multidrug efflux pump D spr1215 ABC-N_P; ABC transporter ATP-binding/membrane-spanning protein - unknown substrate K18888 efrB; ATP-binding cassette, subfamily B, multidrug efflux pump D spr0043 comA; Transport ATP-binding protein ComA K12292 comA; ATP-binding cassette, subfamily C, bacterial, competence factor transporting protein [EC:3.4.22.-] D spr0106 Transporter, truncation K20344 blpA; ATP-binding cassette, subfamily C, bacteriocin exporter C 02060 Phosphotransferase system (PTS) [PATH:spr02060] D spr1062 ptsI; PTS enzyme I K08483 ptsI; phosphoenolpyruvate-protein phosphotransferase (PTS system enzyme I) [EC:2.7.3.9] D spr1063 ptsH; Histidine-containing phosphocarrier protein of the PTS K02784 ptsH; phosphocarrier protein HPr D spr1528 PTS-EII; Phosphotransferase system sugar-specific EII component K02779 ptsG; glucose PTS system EIICB or EIICBA component [EC:2.7.1.199] D spr0668 ptsG; PTS glucose-specific enzyme IIABC component K20108 malT; maltose PTS system EIICB or EIICBA component [EC:2.7.1.208] D spr1566 scrA; Phosphotransferase system enzyme II K02810 scrA; sucrose PTS system EIIBCA or EIIBC component [EC:2.7.1.211] D spr0505 PTS-EII; Phosphotransferase system sugar-specific EII component K02757 bglF; beta-glucoside PTS system EIICBA component [EC:2.7.1.-] D spr1699 treP; Phosphotransferase system, trehalose-specific IIBC component K02819 treB; trehalose PTS system EIIBC or EIIBCA component [EC:2.7.1.201] D spr0358 mtlF; Mannitol-specific enzyme IIA component K02798 cmtB; mannitol PTS system EIIA component [EC:2.7.1.197] D spr0356 mtlA; Mannitol PTS EII K02800 mtlA; mannitol PTS system EIICBA or EIICB component [EC:2.7.1.197] D spr0423 PTS-EII; Phosphotransferase system sugar-specific EII component K02786 lacF; lactose PTS system EIIA component [EC:2.7.1.207] D spr1071 lacF; PTS system, lactose-specific IIA component K02786 lacF; lactose PTS system EIIA component [EC:2.7.1.207] D spr0425 PTS-EII; Phosphotransferase system sugar-specific EII component K02788 lacE; lactose PTS system EIICB component [EC:2.7.1.207] D spr1070 lacE; PTS system, lactose-specific IIBC component K02788 lacE; lactose PTS system EIICB component [EC:2.7.1.207] D spr0229 PTS-EIIA; Phosphotransferase system sugar-specific EIIA component K02759 celC; cellobiose PTS system EIIA component [EC:2.7.1.196 2.7.1.205] D spr0280 PTS-EII; Phosphotransferase system sugar-specific EII component K02759 celC; cellobiose PTS system EIIA component [EC:2.7.1.196 2.7.1.205] D spr1836 ptcA; Phosphotransferase system system, cellobiose-specific IIA component K02759 celC; cellobiose PTS system EIIA component [EC:2.7.1.196 2.7.1.205] D spr0230 PTS-EIIB; Phosphotransferase system sugar-specific EIIB component K02760 celA; cellobiose PTS system EIIB component [EC:2.7.1.196 2.7.1.205] D spr0278 PTS-EII; Phosphotransferase system sugar-specific EII component K02760 celA; cellobiose PTS system EIIB component [EC:2.7.1.196 2.7.1.205] D spr1835 ptcB; Phosphotransferase system system, cellobiose-specific IIB component K02760 celA; cellobiose PTS system EIIB component [EC:2.7.1.196 2.7.1.205] D spr1834 ptcC; Phosphotransferase system system, cellobiose-specific IIC component K02761 celB; cellobiose PTS system EIIC component D spr0231 PTS-EIIC; Phosphotransferase system sugar-specific EIIC component K02761 celB; cellobiose PTS system EIIC component D spr0282 PTS-EII; Phosphotransferase system sugar-specific EII component K02761 celB; cellobiose PTS system EIIC component D spr0421 PTS-EII; Phosphotransferase system sugar-specific EII component K02761 celB; cellobiose PTS system EIIC component D spr0063 PTS-EII; Phosphotransferase system sugar-specific EII component K02793 manXa; mannose PTS system EIIA component [EC:2.7.1.191] D spr1970 PTS-EII; Phosphotransferase system sugar-specific EII component K02793 manXa; mannose PTS system EIIA component [EC:2.7.1.191] D spr0261 manL; Phosphotransferase system, mannose-specific EIIAB K02794 manX; mannose PTS system EIIAB component [EC:2.7.1.191] D spr0061 PTS-EIIC; Phosphotransferase system sugar-specific EIIC component K02795 manY; mannose PTS system EIIC component D spr0260 manM; Phosphotransferase system, mannose-specific EIIC K02795 manY; mannose PTS system EIIC component D spr1968 PTS-EII; Phosphotransferase system sugar-specific EII component K02795 manY; mannose PTS system EIIC component D spr0062 PTS-EIID; Phosphotransferase system sugar-specific EIID component K02796 manZ; mannose PTS system EIID component D spr0259 manN; Phosphotransferase system, mannose-specific EIID K02796 manZ; mannose PTS system EIID component D spr1967 PTS-EII; Phosphotransferase system sugar-specific EII component K02796 manZ; mannose PTS system EIID component D spr0291 PTS-EII; Phosphotransferase system sugar-specific EII component K02744 agaF; N-acetylgalactosamine PTS system EIIA component [EC:2.7.1.-] D spr0293 PTS-EII; Phosphotransferase system sugar-specific EII component K02745 agaV; N-acetylgalactosamine PTS system EIIB component [EC:2.7.1.-] D spr0294 PTS-EII; Phosphotransferase system sugar-specific EII component K02746 agaW; N-acetylgalactosamine PTS system EIIC component D spr0295 PTS-EII; Phosphotransferase system sugar-specific EII component K02747 agaE; N-acetylgalactosamine PTS system EIID component D spr0562 PTS-EII; Phosphotransferase system sugar-specific EII component K20112 gatA; galactose PTS system EIIA component [EC:2.7.1.204] D spr1081 Hypothetical protein K20112 gatA; galactose PTS system EIIA component [EC:2.7.1.204] D spr0563 Hypothetical protein K20113 gatB; galactose PTS system EIIB component [EC:2.7.1.204] D spr1080 Hypothetical protein K20113 gatB; galactose PTS system EIIB component [EC:2.7.1.204] D spr0564 PTS-EII; Phosphotransferase system sugar-specific EII component K20114 gatC; galactose PTS system EIIC component D spr1847 PTS-EII; Phosphotransferase system sugar-specific EII component K02821 ulaC; ascorbate PTS system EIIA or EIIAB component [EC:2.7.1.194] D spr1848 PTS-EII; Phosphotransferase system sugar-specific EII component K02822 ulaB; ascorbate PTS system EIIB component [EC:2.7.1.194] D spr1939 Hypothetical protein K02822 ulaB; ascorbate PTS system EIIB component [EC:2.7.1.194] D spr1849 PTS-EII; Phosphotransferase system sugar-specific EII component K03475 ulaA; ascorbate PTS system EIIC component D spr1938 Conserved hypothetical protein K03475 ulaA; ascorbate PTS system EIIC component D spr0780 fruA; Fructose specific-phosphotransferase system IIBC component K02770 fruA; fructose PTS system EIIBC or EIIC component [EC:2.7.1.202] D spr0779 fruB; Fructose-1-phosphate kinase K00882 fruK; 1-phosphofructokinase [EC:2.7.1.56] C 03070 Bacterial secretion system [PATH:spr03070] D spr1821 secE; Preprotein translocase secE component K03073 secE; preprotein translocase subunit SecE D spr0877 secG; Protein-export membrane protein secG K03075 secG; preprotein translocase subunit SecG D spr0209 secY; Multispanning membrane protein, translocator of proteins K03076 secY; preprotein translocase subunit SecY D spr1840 Conserved hypothetical protein K03210 yajC; preprotein translocase subunit YajC D spr0296 Conserved hypothetical protein K03210 yajC; preprotein translocase subunit YajC D spr1852 Conserved hypothetical protein K03217 yidC; YidC/Oxa1 family membrane protein insertase D spr1790 Conserved hypothetical protein K03217 yidC; YidC/Oxa1 family membrane protein insertase D spr1544 secA; Preprotein translocase secA subunit K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8] D spr1123 ftsY; Cell division protein FtsY K03110 ftsY; fused signal recognition particle receptor D spr1166 ffh; Signal recognition particle (Fifty four homolog) K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4] B B 09132 Signal transduction C 02020 Two-component system [PATH:spr02020] D spr1894 phoR_pnpS; Histidine kinase K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3] D spr1893 phoP_pnpR; Response regulator K07658 phoB1; two-component system, OmpR family, alkaline phosphatase synthesis response regulator PhoP D spr1257 pstS; ABC transporter substrate-binding protein - phosphate transport K02040 pstS; phosphate transport system substrate-binding protein D spr1895 pstS; ABC transporter substrate-binding protein - phosphate transport K02040 pstS; phosphate transport system substrate-binding protein D spr2045 sphtra; Serine protease K04771 degP; serine protease Do [EC:3.4.21.107] D spr1106 hk02; Histidine kinase K07652 vicK; two-component system, OmpR family, sensor histidine kinase VicK [EC:2.7.13.3] D spr1107 rr02; Response regulator K07668 vicR; two-component system, OmpR family, response regulator VicR D spr0001 dnaA; DNA biosynthesis, initiation, binding protein K02313 dnaA; chromosomal replication initiator protein D spr0077 hk08; Histidine kinase K10681 saeS; two-component system, OmpR family, sensor histidine kinase SaeS [EC:2.7.13.3] D spr0076 rr08; Response regulator K10682 saeR; two-component system, OmpR family, response regulator SaeR D spr0813 ABC-MSD; ABC transporter membrane-spanning permease - unknown substrate K19084 braE; bacitracin transport system permease protein D spr0812 ABC-NBD; ABC transporter ATP-binding protein - unknown substrate K19083 braD; bacitracin transport system ATP-binding protein D spr1473 hk01; Histidine kinase K19081 braS; two-component system, OmpR family, sensor histidine kinase BraS/BceS [EC:2.7.13.3] D spr1474 rr01; Response regulator K19082 braR; two-component system, OmpR family, response regulator protein BraR/BceR D spr1982 dltA; D-alanine-D-alanyl carrier protein ligase K03367 dltA; D-alanine--poly(phosphoribitol) ligase subunit 1 [EC:6.1.1.13] D spr1981 dltB; D-alanine transfer from Dcp to undecaprenol-phosphate K03739 dltB; membrane protein involved in D-alanine export D spr1980 dltC; D-alanyl carrier protein K14188 dltC; D-alanine--poly(phosphoribitol) ligase subunit 2 [EC:6.1.1.13] D spr1979 dltD; D-alanine transfer from undecaprenol-phosphate to the poly(glycerophosphate) chain K03740 dltD; D-alanine transfer protein D spr0708 ciaH; Sensor protein CiaH histide kinase K14982 ciaH; two-component system, OmpR family, sensor histidine kinase CiaH [EC:2.7.13.3] D spr0707 ciaR; Response regulator, transcriptional regulatory protein K14983 ciaR; two-component system, OmpR family, response regulator CiaR D spr0554 Conserved hypothetical protein K07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14] D spr1771 nisP; Subtilisin-like serine protease K20486 nisP; lantibiotic leader peptide-processing serine protease [EC:3.4.21.-] D spr0464 hk13; Histidine kinase K07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3] D spr0463 rr13; Response regulator K07707 agrA; two-component system, LytTR family, response regulator AgrA D spr0043 comA; Transport ATP-binding protein ComA K12292 comA; ATP-binding cassette, subfamily C, bacterial, competence factor transporting protein [EC:3.4.22.-] D spr0044 comB; Transport protein ComB K12293 comB; competence factor transport accessory protein ComB D spr2043 comC; Competence stimulating peptide precursor (CSP) K12415 comC; competence-stimulating peptide D spr2042 comD; Histidine protein kinase K12294 comD; two-component system, LytTR family, sensor histidine kinase ComD [EC:2.7.13.3] D spr2041 comE; Response regulator K12295 comE; two-component system, LytTR family, response regulator ComE D spr1819 comX2; Competence-specific global transcription modulator K12296 comX1_2; competence protein ComX D spr0013 comX1; Competence-specific global transcription modulator K12296 comX1_2; competence protein ComX D spr1441 oxlT; Major facilitator:Oxalate:Formate Antiporter K08177 oxlT; MFS transporter, OFA family, oxalate/formate antiporter D spr0009 Conserved hypothetical protein K01467 ampC; beta-lactamase class C [EC:3.5.2.6] D spr1815 hk11; Histidine kinase K07778 desK; two-component system, NarL family, sensor histidine kinase DesK [EC:2.7.13.3] D spr1814 rr11; Response regulator K07693 desR; two-component system, NarL family, response regulator DesR D spr0343 hk03; Histidine kinase K11617 liaS; two-component system, NarL family, sensor histidine kinase LiaS [EC:2.7.13.3] D spr0344 rr03; Response regulator K11618 liaR; two-component system, NarL family, response regulator LiaR D spr0444 glnA; Glutamine synthetase type 1 K01915 glnA; glutamine synthetase [EC:6.3.1.2] D spr0579 hk09; Histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3] D spr0153 hk07; Histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3] D spr0154 rr07; Response regulator K07720 yesN; two-component system, response regulator YesN D spr1839 Conserved hypothetical protein K25307 wzb; low molecular weight protein-tyrosine phosphatase [EC:3.1.3.48] C 04010 MAPK signaling pathway C 04013 MAPK signaling pathway - fly C 04016 MAPK signaling pathway - plant C 04011 MAPK signaling pathway - yeast C 04012 ErbB signaling pathway C 04014 Ras signaling pathway C 04015 Rap1 signaling pathway C 04310 Wnt signaling pathway C 04330 Notch signaling pathway C 04340 Hedgehog signaling pathway C 04341 Hedgehog signaling pathway - fly C 04350 TGF-beta signaling pathway C 04390 Hippo signaling pathway C 04391 Hippo signaling pathway - fly C 04392 Hippo signaling pathway - multiple species C 04370 VEGF signaling pathway C 04371 Apelin signaling pathway C 04630 JAK-STAT signaling pathway C 04064 NF-kappa B signaling pathway C 04668 TNF signaling pathway C 04066 HIF-1 signaling pathway C 04068 FoxO signaling pathway C 04020 Calcium signaling pathway C 04070 Phosphatidylinositol signaling system C 04072 Phospholipase D signaling pathway C 04071 Sphingolipid signaling pathway C 04024 cAMP signaling pathway C 04022 cGMP-PKG signaling pathway C 04151 PI3K-Akt signaling pathway C 04152 AMPK signaling pathway C 04150 mTOR signaling pathway C 04075 Plant hormone signal transduction B B 09133 Signaling molecules and interaction C 04080 Neuroactive ligand-receptor interaction C 04060 Cytokine-cytokine receptor interaction C 04061 Viral protein interaction with cytokine and cytokine receptor C 04512 ECM-receptor interaction C 04514 Cell adhesion molecules # A09140 Cellular Processes B B 09141 Transport and catabolism C 04144 Endocytosis C 04145 Phagosome C 04142 Lysosome C 04146 Peroxisome C 04140 Autophagy - animal C 04138 Autophagy - yeast C 04136 Autophagy - other C 04137 Mitophagy - animal C 04139 Mitophagy - yeast C 04148 Efferocytosis B B 09143 Cell growth and death C 04110 Cell cycle C 04111 Cell cycle - yeast C 04112 Cell cycle - Caulobacter C 04113 Meiosis - yeast C 04114 Oocyte meiosis C 04210 Apoptosis C 04214 Apoptosis - fly C 04215 Apoptosis - multiple species C 04216 Ferroptosis C 04217 Necroptosis C 04115 p53 signaling pathway C 04218 Cellular senescence B B 09144 Cellular community - eukaryotes C 04510 Focal adhesion C 04520 Adherens junction C 04530 Tight junction C 04540 Gap junction C 04550 Signaling pathways regulating pluripotency of stem cells B B 09145 Cellular community - prokaryotes C 02024 Quorum sensing [PATH:spr02024] D spr0308 luxS; Autoinducer-2 production protein K07173 luxS; S-ribosylhomocysteine lyase [EC:4.4.1.21] D spr1637 trpE; Anthranilate synthase component I K01657 trpE; anthranilate synthase component I [EC:4.1.3.27] D spr1636 trpG; Anthranilate synthase component II (glutamine amido-transferase) K01658 trpG; anthranilate synthase component II [EC:4.1.3.27] D spr1542 aroF; Phospho-2-dehydro-3-deoxyheptonate aldolase (DAHP synthatase); possibly tyr-sensitive K01626 E2.5.1.54; 3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54] D spr1543 aroG; phospho-2-dehydro-3-deoxyheptonate aldolase (DAHP synthatase isozyme)-possibly phe sensitive K01626 E2.5.1.54; 3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54] D spr0659 livJ; ABC transporter substrate-binding protein - branched chain amino acid transport K01999 livK; branched-chain amino acid transport system substrate-binding protein D spr0660 livH; ABC transporter membrane-spanning permease - branched chain amino acid transport K01997 livH; branched-chain amino acid transport system permease protein D spr0661 livM; ABC transporter membrane-spanning permease - branched chain amino acid transport K01998 livM; branched-chain amino acid transport system permease protein D spr0662 livG; ABC transporter ATP-binding protein - branched chain amino acid transport K01995 livG; branched-chain amino acid transport system ATP-binding protein D spr0663 livF; ABC transporter ATP-binding protein - branched chain amino acid transport K01996 livF; branched-chain amino acid transport system ATP-binding protein D spr0966 Conserved hypothetical protein K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D spr0164 ribD; Riboflavin biosynthese; a deaminase K11752 ribD; diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase [EC:3.5.4.26 1.1.1.193] D spr0464 hk13; Histidine kinase K07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3] D spr0463 rr13; Response regulator K07707 agrA; two-component system, LytTR family, response regulator AgrA D spr1739 ply; Pneumolysin (sulfhydryl-activated toxin that lyses cholesterol containing membranes) K11031 slo; thiol-activated cytolysin D spr2043 comC; Competence stimulating peptide precursor (CSP) K12415 comC; competence-stimulating peptide D spr0043 comA; Transport ATP-binding protein ComA K12292 comA; ATP-binding cassette, subfamily C, bacterial, competence factor transporting protein [EC:3.4.22.-] D spr0044 comB; Transport protein ComB K12293 comB; competence factor transport accessory protein ComB D spr2042 comD; Histidine protein kinase K12294 comD; two-component system, LytTR family, sensor histidine kinase ComD [EC:2.7.13.3] D spr2041 comE; Response regulator K12295 comE; two-component system, LytTR family, response regulator ComE D spr0708 ciaH; Sensor protein CiaH histide kinase K14982 ciaH; two-component system, OmpR family, sensor histidine kinase CiaH [EC:2.7.13.3] D spr0707 ciaR; Response regulator, transcriptional regulatory protein K14983 ciaR; two-component system, OmpR family, response regulator CiaR D spr1382 aliB; ABC transporter substrate-binding protein - oligopeptide transport K15580 oppA; oligopeptide transport system substrate-binding protein D spr1707 amiA; ABC transporter substrate-binding protein - oligopeptide transport K15580 oppA; oligopeptide transport system substrate-binding protein D spr1706 amiC; ABC transporter membrane-spanning permease - oligopeptide transport K15581 oppB; oligopeptide transport system permease protein D spr1705 amiD; ABC transporter membrane-spanning permease - oligopeptide transport K15582 oppC; oligopeptide transport system permease protein D spr1704 amiE; ABC transporter ATP-binding protein - oligopeptide transport K15583 oppD; oligopeptide transport system ATP-binding protein D spr1703 amiF; ABC transporter ATP-binding protein - oligopeptide transport K10823 oppF; oligopeptide transport system ATP-binding protein D spr1803 plcR; Transcriptional activator K20342 comR; HTH-type transcriptional regulator, regulator for ComX D spr1819 comX2; Competence-specific global transcription modulator K12296 comX1_2; competence protein ComX D spr0013 comX1; Competence-specific global transcription modulator K12296 comX1_2; competence protein ComX D spr0465 ip; Bacteriocin-like peptide, double glycine cleavage type K20343 blpC; peptide pheromone BlpC D spr0106 Transporter, truncation K20344 blpA; ATP-binding cassette, subfamily C, bacteriocin exporter D spr0108 Conserved hypothetical protein K20345 blpB; membrane fusion protein, peptide pheromone/bacteriocin exporter D spr0960 mutR; Similar to positive transcriptional regulator MutR K20374 rgg3; HTH-type transcriptional regulator, SHP3-responsive repressor D spr1194 appA; ABC transporter substrate-binding protein - oligopeptide transport K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein D spr0327 aliA; ABC transporter substrate-binding protein - oligopeptide transport K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein D spr1193 appB; ABC transporter membrane-spanning permease - oligopeptide transport K02033 ABC.PE.P; peptide/nickel transport system permease protein D spr1192 appC; ABC transporter membrane-spanning permease - oligopeptide transport K02034 ABC.PE.P1; peptide/nickel transport system permease protein D spr1191 appD; ABC transporter ATP-binding protein - oligopeptide transport K02031 ddpD; peptide/nickel transport system ATP-binding protein D spr1073 lacD; Tagatose 1,6-diphosphate aldolase K01635 lacD; tagatose 1,6-diphosphate aldolase [EC:4.1.2.40] D spr1852 Conserved hypothetical protein K03217 yidC; YidC/Oxa1 family membrane protein insertase D spr1790 Conserved hypothetical protein K03217 yidC; YidC/Oxa1 family membrane protein insertase D spr1821 secE; Preprotein translocase secE component K03073 secE; preprotein translocase subunit SecE D spr0877 secG; Protein-export membrane protein secG K03075 secG; preprotein translocase subunit SecG D spr0209 secY; Multispanning membrane protein, translocator of proteins K03076 secY; preprotein translocase subunit SecY D spr1840 Conserved hypothetical protein K03210 yajC; preprotein translocase subunit YajC D spr0296 Conserved hypothetical protein K03210 yajC; preprotein translocase subunit YajC D spr1544 secA; Preprotein translocase secA subunit K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8] D spr1123 ftsY; Cell division protein FtsY K03110 ftsY; fused signal recognition particle receptor D spr1166 ffh; Signal recognition particle (Fifty four homolog) K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4] D spr1771 nisP; Subtilisin-like serine protease K20486 nisP; lantibiotic leader peptide-processing serine protease [EC:3.4.21.-] C 05111 Biofilm formation - Vibrio cholerae C 02025 Biofilm formation - Pseudomonas aeruginosa C 02026 Biofilm formation - Escherichia coli B B 09142 Cell motility C 02030 Bacterial chemotaxis C 02040 Flagellar assembly [PATH:spr02040] D spr0146 ABC-SBP; ABC transporter substrate-binding protein - amino acid transport K02424 tcyA; L-cystine transport system substrate-binding protein D spr0979 rpoD; RNA polymerase sigmA FACTOR 70 K03086 rpoD; RNA polymerase primary sigma factor C 04814 Motor proteins C 04820 Cytoskeleton in muscle cells D spr1036 eno; Enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] C 04810 Regulation of actin cytoskeleton # A09150 Organismal Systems B B 09151 Immune system C 04640 Hematopoietic cell lineage C 04610 Complement and coagulation cascades C 04611 Platelet activation C 04613 Neutrophil extracellular trap formation C 04620 Toll-like receptor signaling pathway C 04624 Toll and Imd signaling pathway C 04621 NOD-like receptor signaling pathway C 04622 RIG-I-like receptor signaling pathway C 04623 Cytosolic DNA-sensing pathway C 04625 C-type lectin receptor signaling pathway C 04650 Natural killer cell mediated cytotoxicity C 04612 Antigen processing and presentation C 04660 T cell receptor signaling pathway C 04658 Th1 and Th2 cell differentiation C 04659 Th17 cell differentiation C 04657 IL-17 signaling pathway C 04662 B cell receptor signaling pathway C 04664 Fc epsilon RI signaling pathway C 04666 Fc gamma R-mediated phagocytosis C 04670 Leukocyte transendothelial migration C 04672 Intestinal immune network for IgA production C 04062 Chemokine signaling pathway B B 09152 Endocrine system C 04911 Insulin secretion C 04910 Insulin signaling pathway C 04922 Glucagon signaling pathway C 04923 Regulation of lipolysis in adipocytes C 04920 Adipocytokine signaling pathway C 03320 PPAR signaling pathway C 04929 GnRH secretion C 04912 GnRH signaling pathway C 04913 Ovarian steroidogenesis C 04915 Estrogen signaling pathway C 04914 Progesterone-mediated oocyte maturation C 04917 Prolactin signaling pathway C 04921 Oxytocin signaling pathway C 04926 Relaxin signaling pathway C 04935 Growth hormone synthesis, secretion and action C 04918 Thyroid hormone synthesis C 04919 Thyroid hormone signaling pathway C 04928 Parathyroid hormone synthesis, secretion and action C 04916 Melanogenesis C 04924 Renin secretion C 04614 Renin-angiotensin system C 04925 Aldosterone synthesis and secretion C 04927 Cortisol synthesis and secretion B B 09153 Circulatory system C 04260 Cardiac muscle contraction C 04261 Adrenergic signaling in cardiomyocytes C 04270 Vascular smooth muscle contraction B B 09154 Digestive system C 04970 Salivary secretion C 04971 Gastric acid secretion C 04972 Pancreatic secretion C 04976 Bile secretion C 04973 Carbohydrate digestion and absorption C 04974 Protein digestion and absorption C 04975 Fat digestion and absorption C 04979 Cholesterol metabolism C 04977 Vitamin digestion and absorption C 04981 Folate transport and metabolism [PATH:spr04981] D spr1905 Conserved hypothetical protein K01934 MTHFS; 5-formyltetrahydrofolate cyclo-ligase [EC:6.3.3.2] D spr1429 dfr; Dihydrofolate reductase K00287 DHFR; dihydrofolate reductase [EC:1.5.1.3] D spr0928 glyA; Serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D spr0585 thyA; Thymidylate synthase K00560 thyA; thymidylate synthase [EC:2.1.1.45] C 04980 Cobalamin transport and metabolism C 04978 Mineral absorption B B 09155 Excretory system C 04962 Vasopressin-regulated water reabsorption C 04960 Aldosterone-regulated sodium reabsorption C 04961 Endocrine and other factor-regulated calcium reabsorption C 04964 Proximal tubule bicarbonate reclamation C 04966 Collecting duct acid secretion B B 09156 Nervous system C 04724 Glutamatergic synapse C 04727 GABAergic synapse C 04725 Cholinergic synapse C 04728 Dopaminergic synapse C 04726 Serotonergic synapse C 04720 Long-term potentiation C 04730 Long-term depression C 04723 Retrograde endocannabinoid signaling C 04721 Synaptic vesicle cycle C 04722 Neurotrophin signaling pathway B B 09157 Sensory system C 04744 Phototransduction C 04745 Phototransduction - fly C 04740 Olfactory transduction C 04742 Taste transduction C 04750 Inflammatory mediator regulation of TRP channels B B 09158 Development and regeneration C 04320 Dorso-ventral axis formation C 04360 Axon guidance C 04361 Axon regeneration C 04380 Osteoclast differentiation B B 09149 Aging C 04211 Longevity regulating pathway C 04212 Longevity regulating pathway - worm C 04213 Longevity regulating pathway - multiple species B B 09159 Environmental adaptation C 04710 Circadian rhythm C 04713 Circadian entrainment C 04711 Circadian rhythm - fly C 04712 Circadian rhythm - plant C 04714 Thermogenesis C 04626 Plant-pathogen interaction # A09160 Human Diseases B B 09161 Cancer: overview C 05200 Pathways in cancer C 05202 Transcriptional misregulation in cancer C 05206 MicroRNAs in cancer C 05205 Proteoglycans in cancer C 05204 Chemical carcinogenesis - DNA adducts C 05207 Chemical carcinogenesis - receptor activation C 05208 Chemical carcinogenesis - reactive oxygen species C 05203 Viral carcinogenesis C 05230 Central carbon metabolism in cancer C 05231 Choline metabolism in cancer C 05235 PD-L1 expression and PD-1 checkpoint pathway in cancer B B 09162 Cancer: specific types C 05210 Colorectal cancer C 05212 Pancreatic cancer C 05225 Hepatocellular carcinoma C 05226 Gastric cancer C 05214 Glioma C 05216 Thyroid cancer C 05221 Acute myeloid leukemia C 05220 Chronic myeloid leukemia C 05217 Basal cell carcinoma C 05218 Melanoma C 05211 Renal cell carcinoma C 05219 Bladder cancer C 05215 Prostate cancer C 05213 Endometrial cancer C 05224 Breast cancer C 05222 Small cell lung cancer C 05223 Non-small cell lung cancer B B 09172 Infectious disease: viral C 05166 Human T-cell leukemia virus 1 infection C 05170 Human immunodeficiency virus 1 infection C 05161 Hepatitis B C 05160 Hepatitis C C 05171 Coronavirus disease - COVID-19 C 05164 Influenza A C 05162 Measles C 05168 Herpes simplex virus 1 infection C 05163 Human cytomegalovirus infection C 05167 Kaposi sarcoma-associated herpesvirus infection C 05169 Epstein-Barr virus infection C 05165 Human papillomavirus infection B B 09171 Infectious disease: bacterial C 05110 Vibrio cholerae infection C 05120 Epithelial cell signaling in Helicobacter pylori infection C 05130 Pathogenic Escherichia coli infection C 05132 Salmonella infection C 05131 Shigellosis C 05135 Yersinia infection C 05133 Pertussis C 05134 Legionellosis C 05150 Staphylococcus aureus infection C 05152 Tuberculosis C 05100 Bacterial invasion of epithelial cells D spr1652 Hypothetical protein K13925 pfbA; plasmin and fibronectin-binding protein A B B 09174 Infectious disease: parasitic C 05146 Amoebiasis C 05144 Malaria C 05145 Toxoplasmosis C 05140 Leishmaniasis C 05142 Chagas disease C 05143 African trypanosomiasis B B 09163 Immune disease C 05310 Asthma C 05322 Systemic lupus erythematosus C 05323 Rheumatoid arthritis C 05320 Autoimmune thyroid disease C 05321 Inflammatory bowel disease C 05330 Allograft rejection C 05332 Graft-versus-host disease C 05340 Primary immunodeficiency B B 09164 Neurodegenerative disease C 05010 Alzheimer disease C 05012 Parkinson disease C 05014 Amyotrophic lateral sclerosis C 05016 Huntington disease C 05017 Spinocerebellar ataxia C 05020 Prion disease C 05022 Pathways of neurodegeneration - multiple diseases B B 09165 Substance dependence C 05030 Cocaine addiction C 05031 Amphetamine addiction C 05032 Morphine addiction C 05033 Nicotine addiction C 05034 Alcoholism B B 09166 Cardiovascular disease C 05417 Lipid and atherosclerosis C 05418 Fluid shear stress and atherosclerosis C 05410 Hypertrophic cardiomyopathy C 05412 Arrhythmogenic right ventricular cardiomyopathy C 05414 Dilated cardiomyopathy C 05415 Diabetic cardiomyopathy C 05416 Viral myocarditis B B 09167 Endocrine and metabolic disease C 04930 Type II diabetes mellitus C 04940 Type I diabetes mellitus C 04950 Maturity onset diabetes of the young C 04936 Alcoholic liver disease C 04932 Non-alcoholic fatty liver disease C 04931 Insulin resistance C 04933 AGE-RAGE signaling pathway in diabetic complications C 04934 Cushing syndrome B B 09175 Drug resistance: antimicrobial C 01501 beta-Lactam resistance [PATH:spr01501] D spr0009 Conserved hypothetical protein K01467 ampC; beta-lactamase class C [EC:3.5.2.6] D spr1382 aliB; ABC transporter substrate-binding protein - oligopeptide transport K15580 oppA; oligopeptide transport system substrate-binding protein D spr1707 amiA; ABC transporter substrate-binding protein - oligopeptide transport K15580 oppA; oligopeptide transport system substrate-binding protein D spr1706 amiC; ABC transporter membrane-spanning permease - oligopeptide transport K15581 oppB; oligopeptide transport system permease protein D spr1705 amiD; ABC transporter membrane-spanning permease - oligopeptide transport K15582 oppC; oligopeptide transport system permease protein D spr1704 amiE; ABC transporter ATP-binding protein - oligopeptide transport K15583 oppD; oligopeptide transport system ATP-binding protein D spr1703 amiF; ABC transporter ATP-binding protein - oligopeptide transport K10823 oppF; oligopeptide transport system ATP-binding protein D spr0329 pbpA; Penicillin-binding protein 1A K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4] D spr1909 pbp1b; Penicillin-binding protein 1b K03693 pbp1b; penicillin-binding protein 1B D spr1823 pbp2a; Penicillin-binding protein 2a K12555 pbp2A; penicillin-binding protein 2A [EC:2.4.99.28 3.4.16.4] D spr1517 pbp2b; Penicillin-binding protein 2B K00687 pbp2B; penicillin-binding protein 2B D spr0304 pbpX; Penicillin-binding protein 2X K12556 pbp2X; penicillin-binding protein 2X C 01502 Vancomycin resistance [PATH:spr01502] D spr1515 ddl; D-alanine-D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4] D spr1540 alr; Alanine racemase K01775 alr; alanine racemase [EC:5.1.1.1] D spr1514 murF; UDP-N-acetylmuramoylalanine-D-glutamyl-lysine-D-alanyl-D-alanine ligase K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10] D spr0305 mraY; Undecaprenyl-phosphate-UDP-MurNAc-pentapeptide phospho-MurNAc-pentapeptide transferase K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13] D spr0604 murG; Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227] D spr0554 Conserved hypothetical protein K07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14] C 01503 Cationic antimicrobial peptide (CAMP) resistance [PATH:spr01503] D spr2045 sphtra; Serine protease K04771 degP; serine protease Do [EC:3.4.21.107] D spr0679 ppiA; Peptidyl-prolyl cis-trans isomerase K03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8] D spr1982 dltA; D-alanine-D-alanyl carrier protein ligase K03367 dltA; D-alanine--poly(phosphoribitol) ligase subunit 1 [EC:6.1.1.13] D spr1981 dltB; D-alanine transfer from Dcp to undecaprenol-phosphate K03739 dltB; membrane protein involved in D-alanine export D spr1980 dltC; D-alanyl carrier protein K14188 dltC; D-alanine--poly(phosphoribitol) ligase subunit 2 [EC:6.1.1.13] D spr1979 dltD; D-alanine transfer from undecaprenol-phosphate to the poly(glycerophosphate) chain K03740 dltD; D-alanine transfer protein B B 09176 Drug resistance: antineoplastic C 01521 EGFR tyrosine kinase inhibitor resistance C 01524 Platinum drug resistance C 01523 Antifolate resistance C 01522 Endocrine resistance # A09180 Brite Hierarchies B B 09181 Protein families: metabolism C 01000 Enzymes [BR:spr01000] C 01001 Protein kinases [BR:spr01001] D spr1577 pkn2; Eukaryotic-type serine/threonine kinase K12132 prkC; eukaryotic-like serine/threonine-protein kinase [EC:2.7.11.1] D spr1894 phoR_pnpS; Histidine kinase K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3] D spr1106 hk02; Histidine kinase K07652 vicK; two-component system, OmpR family, sensor histidine kinase VicK [EC:2.7.13.3] D spr0077 hk08; Histidine kinase K10681 saeS; two-component system, OmpR family, sensor histidine kinase SaeS [EC:2.7.13.3] D spr1473 hk01; Histidine kinase K19081 braS; two-component system, OmpR family, sensor histidine kinase BraS/BceS [EC:2.7.13.3] D spr0708 ciaH; Sensor protein CiaH histide kinase K14982 ciaH; two-component system, OmpR family, sensor histidine kinase CiaH [EC:2.7.13.3] D spr1815 hk11; Histidine kinase K07778 desK; two-component system, NarL family, sensor histidine kinase DesK [EC:2.7.13.3] D spr0343 hk03; Histidine kinase K11617 liaS; two-component system, NarL family, sensor histidine kinase LiaS [EC:2.7.13.3] D spr0464 hk13; Histidine kinase K07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3] D spr2042 comD; Histidine protein kinase K12294 comD; two-component system, LytTR family, sensor histidine kinase ComD [EC:2.7.13.3] D spr0579 hk09; Histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3] D spr0153 hk07; Histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3] C 01009 Protein phosphatases and associated proteins [BR:spr01009] D spr0796 pfkA; 6-phosphofructokinase I K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] D spr1578 pppL; Phosphoprotein phosphatase K20074 prpC; PPM family protein phosphatase [EC:3.1.3.16] C 01002 Peptidases and inhibitors [BR:spr01002] D spr0829 lspA; Signal peptidase type II; lipoprotein signal peptidase K03101 lspA; signal peptidase II [EC:3.4.23.36] D spr0258 pepC; Aminopeptidase C K01372 BLMH; bleomycin hydrolase [EC:3.4.22.40] D spr0762 pcp; Pyrrolidone-carboxylate peptidase (5-oxoprolyl-peptidase) K01304 pcp; pyroglutamyl-peptidase [EC:3.4.19.3] D spr1300 guaA; Glutamine amidotransferase K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] D spr1884 guaA; Glutamine amidotransferase K07010 K07010; putative glutamine amidotransferase D spr0997 Conserved hypothetical protein K07010 K07010; putative glutamine amidotransferase D spr0043 comA; Transport ATP-binding protein ComA K12292 comA; ATP-binding cassette, subfamily C, bacterial, competence factor transporting protein [EC:3.4.22.-] D spr0106 Transporter, truncation K20344 blpA; ATP-binding cassette, subfamily C, bacteriocin exporter D spr2021 gsp-781; General stress protein GSP-781 K21471 cwlO; peptidoglycan DL-endopeptidase CwlO [EC:3.4.-.-] D spr0047 purF; Amidophosphoribosyl transferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14] D spr0245 glmS; L-glutamine-D-fructose-6-phosphate amidotransferase K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] D spr0713 thiJ; 4-methyl-5(b-hydroxyethyl)-thiazole monophosphate biosynthesis protein K03152 thiJ; protein deglycase [EC:3.5.1.124] D spr1098 srtA; Sortase K07284 srtA; sortase A [EC:3.4.22.70] D spr0265 Conserved hypothetical protein K07052 K07052; CAAX protease family protein D spr0142 Hypothetical protein K07052 K07052; CAAX protease family protein D spr0167 Conserved hypothetical protein K07052 K07052; CAAX protease family protein D spr0472 blpY; BlpY protein K07052 K07052; CAAX protease family protein D spr0474 pncP; ABC transporter ATP binding protein - unknown substrate K07052 K07052; CAAX protease family protein D spr0826 Hypothetical protein K07052 K07052; CAAX protease family protein D spr1206 Hypothetical protein K07052 K07052; CAAX protease family protein D spr1926 Hypothetical protein K07052 K07052; CAAX protease family protein D spr1119 Conserved hypothetical protein K07052 K07052; CAAX protease family protein D spr0143 Hypothetical protein K07052 K07052; CAAX protease family protein D spr0706 pepN; Aminopeptidase N K01256 pepN; aminopeptidase N [EC:3.4.11.2] D spr0882 pepB; Group B oligopeptidase K08602 pepF; oligoendopeptidase F [EC:3.4.24.-] D spr1491 pepO; Endopeptidase O K07386 pepO; putative endopeptidase [EC:3.4.24.-] D spr0554 Conserved hypothetical protein K07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14] D spr0547 pepV; Dipeptidase K01274 pepV; beta-Ala-Xaa dipeptidase [EC:3.4.13.-] D spr0148 dapE; Succinyl-diaminopimelic descuccinlyase (ArgE/DapE/Acy1 family protein) K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18] D spr0913 pepT; Aminotripeptidase; tripeptidase K01258 pepT; tripeptide aminopeptidase [EC:3.4.11.4] D spr1906 hipO; Similar to several hippurate hydrolases and amino acid amidohydrolases; can be a peptidase too K05823 dapL; N-acetyldiaminopimelate deacetylase [EC:3.5.1.47] D spr0992 map; Methionine aminopeptidase K01265 map; methionyl aminopeptidase [EC:3.4.11.18] D spr0172 pepP; Aminopeptidase P K01262 pepP; Xaa-Pro aminopeptidase [EC:3.4.11.9] D spr1042 iga; Immunoglobulin A1 protease K01390 iga; IgA-specific metalloendopeptidase [EC:3.4.24.13] D spr0581 zmpB; Zinc metalloprotease K08643 zmpB; zinc metalloprotease ZmpB [EC:3.4.24.-] D spr0254 pepS; Aminopeptidase K19689 ampS; aminopeptidase [EC:3.4.11.-] D spr0012 ftsH; Cell-division protein / general stress protein (class III heat-shock) K03798 ftsH; cell division protease FtsH [EC:3.4.24.-] D spr1682 pepA; Glutamyl aminopeptidase K01261 pepA; glutamyl aminopeptidase [EC:3.4.11.7] D spr0552 Conserved hypothetical protein K01269 yhfE; aminopeptidase [EC:3.4.11.-] D spr1162 htpX; Heat shock protein K03799 htpX; heat shock protein HtpX [EC:3.4.24.-] D spr0242 eep; Determinant for enhanced expression of pheromone K11749 rseP; regulator of sigma E protease [EC:3.4.24.-] D spr2045 sphtra; Serine protease K04771 degP; serine protease Do [EC:3.4.21.107] D spr1771 nisP; Subtilisin-like serine protease K20486 nisP; lantibiotic leader peptide-processing serine protease [EC:3.4.21.-] D spr1204 ptrB; Protease II (oligopeptidase B) K01354 ptrB; oligopeptidase B [EC:3.4.21.83] D spr0776 dacA; D-alanyl-D-alanine carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] D spr0656 clpP; ATP-dependent CLP protease proteolytic subunit K01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92] D spr0794 pepXP; Xaa-pro dipeptidyl-peptidase K01281 pepX; X-Pro dipeptidyl-peptidase [EC:3.4.14.11] D spr1782 Conserved hypothetical protein K07177 K07177; Lon-like protease D spr0364 spi; Signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89] D spr1284 Protease K08303 prtC; U32 family peptidase [EC:3.4.-.-] D spr1282 Hypothetical protein K08303 prtC; U32 family peptidase [EC:3.4.-.-] C 01003 Glycosyltransferases [BR:spr01003] D spr0982 Conserved Hypothetical protein K19002 mgs; 1,2-diacylglycerol 3-alpha-glucosyltransferase [EC:2.4.1.337] D spr0981 cpoA; Glycosyltransferase K13678 cpoA; 1,2-diacylglycerol-3-alpha-glucose alpha-1,2-galactosyltransferase [EC:2.4.1.-] D spr1032 glgA; Glycogen synthase K00703 glgA; starch synthase [EC:2.4.1.21] D spr0329 pbpA; Penicillin-binding protein 1A K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4] D spr1909 pbp1b; Penicillin-binding protein 1b K03693 pbp1b; penicillin-binding protein 1B D spr1823 pbp2a; Penicillin-binding protein 2a K12555 pbp2A; penicillin-binding protein 2A [EC:2.4.99.28 3.4.16.4] D spr1655 Conserved hypothetical protein K25627 wbgY; AATGal transferase D spr0091 Conserved hypothetical protein K25650 K25650; teichoic acid beta-1,3-glucosyltransferase [EC:2.4.1.-] D spr1223 cps23FU; Galactosyl transferase paralog K25652 K25652; teichoic acid N-acetylgalactosaminyltransferase [EC:2.4.1.-] D spr1224 Conserved hypothetical protein K25653 K25653; teichoic acid N-acetylgalactosaminyltransferase [EC:2.4.1.-] C 01005 Lipopolysaccharide biosynthesis proteins [BR:spr01005] D spr1459 gtrB; Glycosil transferase K12999 rgpI; glucosyltransferase [EC:2.4.1.-] C 01011 Peptidoglycan biosynthesis and degradation proteins [BR:spr01011] D spr0989 murZ; UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7] D spr1781 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7] D spr1247 murB; UDP-N-acetylenolpyruvoylglucosamine reductase K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98] D spr1373 murC; UDP-N-acetylmuramate-alanine ligase K01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8] D spr0603 murD; UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9] D spr1384 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine Ligase K05362 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-L-lysine ligase [EC:6.3.2.7] D spr1515 ddl; D-alanine-D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4] D spr0540 murM; Serine/alanine adding enzyme K05363 murM; serine/alanine adding enzyme [EC:2.3.2.10] D spr0541 murN; Alanine adding enzyme K12554 murN; alanine adding enzyme [EC:2.3.2.-] D spr1540 alr; Alanine racemase K01775 alr; alanine racemase [EC:5.1.1.1] D spr1696 murI; Glutamate racemase K01776 murI; glutamate racemase [EC:5.1.1.3] D spr0305 mraY; Undecaprenyl-phosphate-UDP-MurNAc-pentapeptide phospho-MurNAc-pentapeptide transferase K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13] D spr0604 murG; Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227] D spr0413 bacA; A lipid kinase; may confer bacitracin resistance by phosphorylation of undecaprenol K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27] D spr0434 Conserved hypothetical protein K19302 bcrC; undecaprenyl-diphosphatase [EC:3.6.1.27] D spr0329 pbpA; Penicillin-binding protein 1A K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4] D spr1909 pbp1b; Penicillin-binding protein 1b K03693 pbp1b; penicillin-binding protein 1B D spr1823 pbp2a; Penicillin-binding protein 2a K12555 pbp2A; penicillin-binding protein 2A [EC:2.4.99.28 3.4.16.4] D spr1517 pbp2b; Penicillin-binding protein 2B K00687 pbp2B; penicillin-binding protein 2B D spr0304 pbpX; Penicillin-binding protein 2X K12556 pbp2X; penicillin-binding protein 2X D spr0776 dacA; D-alanyl-D-alanine carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] D spr0554 Conserved hypothetical protein K07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14] D spr2021 gsp-781; General stress protein GSP-781 K21471 cwlO; peptidoglycan DL-endopeptidase CwlO [EC:3.4.-.-] D spr1098 srtA; Sortase K07284 srtA; sortase A [EC:3.4.22.70] D spr1370 Hypothetical protein K07082 mltG; peptidoglycan lytic transglycosylase G [EC:4.2.2.29] C 01004 Lipid biosynthesis proteins [BR:spr01004] D spr0380 fabD; Malonyl acyl carrier protein transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39] D spr0377 fabH; 3-oxoacyl-acyl-carrier-protein synthase III K00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180] D spr0382 fabF; Beta ketoacyl-acyl carrier protein synthase K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179] D spr0381 fabG; 3-ketoacyl-acyl carrier protein reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D spr0701 fabG; 3-Ketoacyl-ACP reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D spr0384 fabZ; Hydroxymyristoyl-(acyl carrier protein) dehydratase K02372 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59] D spr0379 fabK; Enoyl-acyl carrier protein(ACP) reductase K02371 fabK; enoyl-[acyl-carrier protein] reductase II [EC:1.3.1.9] D spr0375 phaB; Enoyl-CoA hydratase II K18474 fabM; trans-2-decenoyl-[acyl-carrier protein] isomerase [EC:5.3.3.14] D spr0966 Conserved hypothetical protein K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D spr0037 plsX; Involved in fatty acid/phospholipid synthesis K03621 plsX; phosphate acyltransferase [EC:2.3.1.274] D spr0755 Conserved hypothetical protein K08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275] D spr1465 Conserved hypothetical protein K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51] C 01008 Polyketide biosynthesis proteins C 01006 Prenyltransferases [BR:spr01006] D spr1087 ispA; Farnesyl diphosphate synthase K13789 GGPS; geranylgeranyl diphosphate synthase, type II [EC:2.5.1.1 2.5.1.10 2.5.1.29] D spr0240 uppS; Undecaprenyl diphosphate synthase K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31] D spr0588 miaA; tRNA isopentenylpyrophosphate transferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75] C 01007 Amino acid related enzymes [BR:spr01007] D spr1881 gltX; Glutamyl-tRNA synthetase (glutamate--tRNA ligase) K09698 gltX; nondiscriminating glutamyl-tRNA synthetase [EC:6.1.1.24] D spr1910 tyrS; Tyrosyl-tRNA synthetase 1 K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D spr2034 trpS; Tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2] D spr0519 cysS; Cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16] D spr1890 argS; Arginyl-tRNA synthetase(arginine--tRNA ligase) (ARGRS) K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D spr0696 metS; Methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] D spr1502 ileS; Isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5] D spr0492 valS; Valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9] D spr0235 leuS; Leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D spr0626 lysS; Lysyl-tRNA synthetase (lysine--tRNA ligase) (LYSRS) K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6] D spr1924 aspS; Aspartyl-tRNA synthetase (aspartate-tRNA ligase) K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12] D spr1397 asnS; Asparaginyl-tRNA synthetase (asparagine--tRNA ligase) K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22] D spr1931 hisS; Histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21] D spr1329 glyQ; Glycyl-tRNA synthetase alpha chain K01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14] D spr1328 glyS; Glycyl-tRNA synthetase beta chain K01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14] D spr0372 serS; Seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11] D spr0243 proS; Prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15] D spr1472 thrS; Threonyl-tRNA synthetase 1 K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3] D spr1240 alaS; Alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7] D spr0507 pheS; Phenylalanyl-tRNA synthetase alpha chain K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20] D spr0509 pheT; Phenylalanyl-tRNA synthetase beta chain K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20] D spr1808 aspC; Potential aminotransferase K14260 alaA; alanine-synthesizing transaminase [EC:2.6.1.66 2.6.1.2] D spr0035 aspC; Aspartate aminotransferase K00841 patA; aminotransferase [EC:2.6.1.-] D spr1376 patB; Aminotransferase K14155 patB; cysteine-S-conjugate beta-lyase [EC:4.4.1.13] D spr0758 ilvE; Branched-chain-amino-acid transaminase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] D spr0582 pabB; Para-aminobenzoate synthetase K03342 pabBC; para-aminobenzoate synthetase / 4-amino-4-deoxychorismate lyase [EC:2.6.1.85 4.1.3.38] C 00199 Cytochrome P450 C 00194 Photosynthesis proteins [BR:spr00194] D spr1359 atpC; Proton-translocating ATPase, F1 sector, epsilon-subunit K02114 ATPF1E; F-type H+-transporting ATPase subunit epsilon D spr1360 atpD; Proton-translocating ATPase, F1 sector, beta-subunit K02112 ATPF1B; F-type H+/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1] D spr1361 atpG; Proton-translocating ATPase, F1 sector, gamma-subunit K02115 ATPF1G; F-type H+-transporting ATPase subunit gamma D spr1362 atpA; Proton-translocating ATPase, F1 sector, alpha-subunit K02111 ATPF1A; F-type H+/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1] D spr1363 atpH; Proton-translocating ATPase, F1 sector, delta-subunit K02113 ATPF1D; F-type H+-transporting ATPase subunit delta D spr1364 atpF; Proton-translocating ATPase, F0 sector, subunit b K02109 ATPF0B; F-type H+-transporting ATPase subunit b D spr1366 atpE; Proton-translocating ATPase, F0 sector, subunit c K02110 ATPF0C; F-type H+-transporting ATPase subunit c D spr1365 atpB; Proton-translocating ATPase, F0 sector, subunit a K02108 ATPF0A; F-type H+-transporting ATPase subunit a B B 09182 Protein families: genetic information processing C 03000 Transcription factors [BR:spr03000] D spr1067 lacR; Lactose phosphotransferase system repressor K02530 lacR; DeoR family transcriptional regulator, lactose phosphotransferase system repressor D spr0778 fruR; Transcriptional repressor of the fructose operon K03436 fruR2; DeoR family transcriptional regulator, fructose operon transcriptional repressor D spr1621 scrR; Sucrose operon repressor (SCR operon regulatory protein) K02529 galR; LacI family transcriptional regulator, galactose operon repressor D spr1669 galR; GalR, member of GalR-LacI family of transcriptional regulators, binds DNA; regulator of gal operon K02529 galR; LacI family transcriptional regulator, galactose operon repressor D spr1813 ccpA; Catabolite control protein A K02529 galR; LacI family transcriptional regulator, galactose operon repressor D spr1922 malR; Maltose operon transcriptional repressor K02529 galR; LacI family transcriptional regulator, galactose operon repressor D spr1569 scrR; Sucrose regulon regulatory protein K03484 scrR; LacI family transcriptional regulator, sucrose operon repressor D spr1700 treR; Trehalose operon transcriptional repressor K03486 treR2; GntR family transcriptional regulator, trehalose operon transcriptional repressor D spr1832 Conserved hypothetical protein K03492 gmuR; GntR family transcriptional regulator, regulator of glucomannan utilization D spr1301 Conserved hypothetical protein K24967 nagR; GntR family transcriptional regulator, N-acetylglucosamine utilization regulator D spr0443 glnR; Transcriptional repressor of the glutamine synthetase gene K03713 glnR; MerR family transcriptional regulator, glutamine synthetase repressor D spr0697 Conserved hypothetical protein K10947 K10947; PadR family transcriptional regulator D spr0089 Conserved hypothetical protein K10947 K10947; PadR family transcriptional regulator D spr1480 marR; Metalloregulator K03709 troR; DtxR family transcriptional regulator, Mn-dependent transcriptional regulator D spr1715 birA; Biotin--[acetyl-CoA-carboxylase] ligase K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15] D spr0951 Hypothetical protein K18830 pezA; HTH-type transcriptional regulator / antitoxin PezA D spr1803 plcR; Transcriptional activator K20342 comR; HTH-type transcriptional regulator, regulator for ComX D spr0960 mutR; Similar to positive transcriptional regulator MutR K20374 rgg3; HTH-type transcriptional regulator, SHP3-responsive repressor D spr1793 purR; Activator of purine biosynthetic genes K09685 purR; HTH-type transcriptional regulator, purine operon repressor D spr0998 Conserved hypothetical protein K01926 rex; redox-sensing transcriptional repressor D spr1439 codY; Transcriptional pleiotropic repressor K03706 codY; transcriptional pleiotropic repressor D spr0933 Hypothetical protein K07727 K07727; putative transcriptional regulator D spr1929 Conserved hypothetical protein K07729 K07729; putative transcriptional regulator D spr1279 Conserved hypothetical protein K07729 K07729; putative transcriptional regulator D spr0301 yorfE; Transcription regulator K07729 K07729; putative transcriptional regulator D spr0504 licT; Transcriptional antiterminator (BglG family) K03488 licT; beta-glucoside operon transcriptional antiterminator D spr1843 Conserved hypothetical protein K03493 bglG1; transcriptional antiterminator D spr0357 Conserved hypothetical protein K03483 mtlR; mannitol operon transcriptional activator D spr0279 bglG; Transcription antiterminator BglG family K03491 licR; probable licABCH operon transcriptional regulator D spr2046 spo0J; Chromosome segregation protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein D spr1072 lacT; Antiterminator protein K02531 lacT; transcriptional antiterminator D spr0793 argR; Arginine repressor K03402 argR; transcriptional regulator of arginine metabolism D spr1889 argR; Arginine repressor K03402 argR; transcriptional regulator of arginine metabolism D spr1085 ahrC; Transcriptional regulator of arginine metabolism expression K03402 argR; transcriptional regulator of arginine metabolism D spr0453 hrcA; Heat inducible transcription repressor K03705 hrcA; heat-inducible transcriptional repressor D spr0634 tenA; Transcriptional regulator of extracellular enzyme genes K03707 tenA; thiaminase (transcriptional activator TenA) [EC:3.5.99.2] D spr0628 Conserved hypothetical protein K03707 tenA; thiaminase (transcriptional activator TenA) [EC:3.5.99.2] D spr2001 ctsR; Transcriptional regulator CtsR K03708 ctsR; transcriptional regulator of stress and heat shock response D spr1156 pyrR; Transcriptional attenuation of the pyrimidine operon / uracil phosphoribosyltransferase activity K02825 pyrR; pyrimidine operon attenuation protein / uracil phosphoribosyltransferase [EC:2.4.2.9] D spr1557 Conserved hypothetical protein K07738 nrdR; transcriptional repressor NrdR D spr1819 comX2; Competence-specific global transcription modulator K12296 comX1_2; competence protein ComX D spr0013 comX1; Competence-specific global transcription modulator K12296 comX1_2; competence protein ComX C 03021 Transcription machinery [BR:spr03021] D spr0215 rpoA; RNA polymerase alpha subunit K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6] D spr1777 rpoB; DNA-dependent RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6] D spr1776 rpoC; DNA-dependent RNA polymerase K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] D spr0437 rpoE; RNA polymerase (delta subunit) K03048 rpoE; DNA-directed RNA polymerase subunit delta D spr1582 Hypothetical protein K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6] D spr0979 rpoD; RNA polymerase sigmA FACTOR 70 K03086 rpoD; RNA polymerase primary sigma factor D spr0478 nusA; Transcription termination K02600 nusA; transcription termination/antitermination protein NusA D spr0390 nusB; Transcription termination protein K03625 nusB; transcription antitermination protein NusB D spr1820 nusG; Transcription antitermination factor K02601 nusG; transcription termination/antitermination protein NusG D spr1369 greA; Transcription elongation factor GreA K03624 greA; transcription elongation factor GreA C 03019 Messenger RNA biogenesis [BR:spr03019] D spr1127 rncS; Ribonuclease III K03685 rnc; ribonuclease III [EC:3.1.26.3] D spr0125 Conserved hypothetical protein K12574 rnj; ribonuclease J [EC:3.1.-.-] D spr0538 Conserved hypothetical protein K12574 rnj; ribonuclease J [EC:3.1.-.-] D spr1584 Conserved hypothetical protein K18682 rny; ribonucrease Y [EC:3.1.-.-] D spr0878 rnr; Exoribonuclease R K12573 rnr; ribonuclease R [EC:3.1.13.1] D spr1794 cbf1; Cmp-binding-factor 1 K03698 cbf; 3'-5' exoribonuclease [EC:3.1.-.-] D spr1440 Conserved hypothetical protein K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7] D spr0670 rheB; ATP-dependent RNA helicase K18692 cshB; ATP-dependent RNA helicase CshB [EC:5.6.2.7] D spr1036 eno; Enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D spr0516 pnpA; Polyribonucleotide nucleotidyltransferase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] D spr0796 pfkA; 6-phosphofructokinase I K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] D spr0455 dnaK; Class I heat-shock protein (molecular chaperone) K04043 dnaK; molecular chaperone DnaK D spr1722 groEL; Chaperonin GroEL K04077 groEL; chaperonin GroEL [EC:5.6.1.7] D spr1424 Conserved hypothetical protein K06958 rapZ; RNase adapter protein RapZ C 03041 Spliceosome C 03011 Ribosome [BR:spr03011] D spr0764 rpsA; 30S Ribosomal protein S1 K02945 RP-S1; small subunit ribosomal protein S1 D spr2020 rpsB; 30S Ribosomal protein S2 K02967 RP-S2; small subunit ribosomal protein S2 D spr0195 rpsC; 30S Ribosomal protein S3 K02982 RP-S3; small subunit ribosomal protein S3 D spr0078 rpsD; 30S Ribosomal protein S4 K02986 RP-S4; small subunit ribosomal protein S4 D spr0206 rpsE; 30S Ribosomal protein S5 K02988 RP-S5; small subunit ribosomal protein S5 D spr1396 rpsF; 30S Ribosomal protein S6 (S6) K02990 RP-S6; small subunit ribosomal protein S6 D spr0249 rpsG; 30S Ribosomal protein S7 K02992 RP-S7; small subunit ribosomal protein S7 D spr0203 rpsH; 30S Ribosomal protein S8 (S8) K02994 RP-S8; small subunit ribosomal protein S8 D spr0272 rpsI; 30S Ribosomal protein S9 K02996 RP-S9; small subunit ribosomal protein S9 D spr0187 rpsJ; 30S Ribosomal protein S10 K02946 RP-S10; small subunit ribosomal protein S10 D spr0214 rpsK; 30S Ribosomal protein S11 K02948 RP-S11; small subunit ribosomal protein S11 D spr0248 rpsL; 30S Ribosomal protein S12 K02950 RP-S12; small subunit ribosomal protein S12 D spr0213 rpsM; 30S Ribosomal protein S13 K02952 RP-S13; small subunit ribosomal protein S13 D spr0202 rpsN; 30S Ribosomal protein S14 K02954 RP-S14; small subunit ribosomal protein S14 D spr1467 rpsO; 30S Ribosomal protein S15 K02956 RP-S15; small subunit ribosomal protein S15 D spr0682 rpsP; 30S Ribosomal protein S16 K02959 RP-S16; small subunit ribosomal protein S16 D spr0198 rpsQ; 30S Ribosomal protein S17 K02961 RP-S17; small subunit ribosomal protein S17 D spr1394 rpsR; 30S Ribosomal protein S18 K02963 RP-S18; small subunit ribosomal protein S18 D spr0192 rpsS; 30S Ribosomal protein S19 K02965 RP-S19; small subunit ribosomal protein S19 D spr0740 rpsT; 30S Ribosomal protein subunit S20 K02968 RP-S20; small subunit ribosomal protein S20 D spr1271 rpsU; 30S Ribosomal protein S21 K02970 RP-S21; small subunit ribosomal protein S21 D spr0556 rplA; 50S Ribosomal protein L1 K02863 RP-L1; large subunit ribosomal protein L1 D spr0191 rplB; 50S Ribosomal protein L2 K02886 RP-L2; large subunit ribosomal protein L2 D spr0188 rplC; 50S Ribosomal protein L3 K02906 RP-L3; large subunit ribosomal protein L3 D spr0189 rplD; 50S Ribosomal protein L4 K02926 RP-L4; large subunit ribosomal protein L4 D spr0201 rplE; 50S Ribosomal protein L5 K02931 RP-L5; large subunit ribosomal protein L5 D spr0204 rplF; 50S Ribosomal protein L6 K02933 RP-L6; large subunit ribosomal protein L6 D spr2009 rplI; 50S Ribosomal protein subunit L9 K02939 RP-L9; large subunit ribosomal protein L9 D spr1212 rplJ; 50S Ribosomal protein L10 K02864 RP-L10; large subunit ribosomal protein L10 D spr0555 rplK; 50S Ribosomal protein L11 K02867 RP-L11; large subunit ribosomal protein L11 D spr1211 rplL; 50S Ribosomal protein L12 K02935 RP-L7; large subunit ribosomal protein L7/L12 D spr0271 rplM; 50S Ribosomal protein L13 K02871 RP-L13; large subunit ribosomal protein L13 D spr0199 rplN; 50S Ribosomal protein L14 K02874 RP-L14; large subunit ribosomal protein L14 D spr0208 rplO; 50S Ribosomal protein L15 K02876 RP-L15; large subunit ribosomal protein L15 D spr0196 rplP; 50S Ribosomal protein L16 K02878 RP-L16; large subunit ribosomal protein L16 D spr0216 rplQ; 50S Ribosomal protein L17 K02879 RP-L17; large subunit ribosomal protein L17 D spr0205 rplR; 50S Ribosomal protein L18 K02881 RP-L18; large subunit ribosomal protein L18 D spr1171 rplS; 50S Ribosomal protein L19 K02884 RP-L19; large subunit ribosomal protein L19 D spr0863 rplT; 50S Ribosomal protein L20 K02887 RP-L20; large subunit ribosomal protein L20 D spr1012 rplU; 50S Ribosomal protein L21 K02888 RP-L21; large subunit ribosomal protein L21 D spr0194 rplV; 50S Ribosomal protein L22 K02890 RP-L22; large subunit ribosomal protein L22 D spr0190 rplW; 50S Ribosomal protein L23 K02892 RP-L23; large subunit ribosomal protein L23 D spr0200 rplX; 50S Ribosomal protein L24 K02895 RP-L24; large subunit ribosomal protein L24 D spr1014 rpmA; 50S Ribosomal protein L27 K02899 RP-L27; large subunit ribosomal protein L27 D spr0398 rpmB; 50S Ribosomal protein L28 K02902 RP-L28; large subunit ribosomal protein L28 D spr0197 rpmC; 50S Ribosomal protein L29 K02904 RP-L29; large subunit ribosomal protein L29 D spr0207 rpmD; 50S Ribosomal protein L30 K02907 RP-L30; large subunit ribosomal protein L30 D spr1177 rpmE; 50S ribosomal protein L31 K02909 RP-L31; large subunit ribosomal protein L31 D spr1943 rpmF; 50S Ribosomal protein L32 K02911 RP-L32; large subunit ribosomal protein L32 D spr0876 rpmG; 50S Ribosomal protein L33 K02913 RP-L33; large subunit ribosomal protein L33 D spr1822 rpmG; 50S Ribosomal protein L33 K02913 RP-L33; large subunit ribosomal protein L33 D spr1944 rpmG; 50S Ribosomal protein L33 K02913 RP-L33; large subunit ribosomal protein L33 D spr1807 rpmH; 50S Ribosomal protein L34 K02914 RP-L34; large subunit ribosomal protein L34 D spr0862 rpmI; 50S Ribosomal protein L35 K02916 RP-L35; large subunit ribosomal protein L35 D spr0212 rpmJ; 50S Ribosomal protein L36 K02919 RP-L36; large subunit ribosomal protein L36 D sprr03 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D sprr04 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D sprr07 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D sprr10 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D sprr01 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D sprr06 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D sprr09 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D sprr12 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D sprr02 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D sprr05 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D sprr08 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D sprr11 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA C 03009 Ribosome biogenesis [BR:spr03009] D spr1127 rncS; Ribonuclease III K03685 rnc; ribonuclease III [EC:3.1.26.3] D spr0871 era; GTPase/GTP-binding protein K03595 era; GTPase D spr0984 obg; GTP-binding protein K03979 obgE; GTPase [EC:3.6.5.-] D spr0478 nusA; Transcription termination K02600 nusA; transcription termination/antitermination protein NusA D spr0390 nusB; Transcription termination protein K03625 nusB; transcription antitermination protein NusB D spr1820 nusG; Transcription antitermination factor K02601 nusG; transcription termination/antitermination protein NusG D spr0597 rsuA; Ribosomal small subunit pseudouridine synthase A K06183 rsuA; 16S rRNA pseudouridine516 synthase [EC:5.4.99.19] D spr0256 rsuA; Ribosomal small subunit pseudouridine synthase A K06183 rsuA; 16S rRNA pseudouridine516 synthase [EC:5.4.99.19] D spr1799 ksgA; Dimethyladenosine transferase K02528 ksgA; 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase [EC:2.1.1.182] D spr1579 sunL; rRNA methylase K03500 rsmB; 16S rRNA (cytosine967-C5)-methyltransferase [EC:2.1.1.176] D spr0743 Conserved hypothetical protein K00564 rsmC; 16S rRNA (guanine1207-N2)-methyltransferase [EC:2.1.1.172] D spr1784 Conserved hypothetical protein K08316 rsmD; 16S rRNA (guanine966-N2)-methyltransferase [EC:2.1.1.171] D spr1607 Conserved hypothetical protein K09761 rsmE; 16S rRNA (uracil1498-N3)-methyltransferase [EC:2.1.1.193] D spr1164 gidB; Glucose inhibited division protein B K03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170] D spr0302 yllC; YllC protein K03438 mraW; 16S rRNA (cytosine1402-N4)-methyltransferase [EC:2.1.1.199] D spr0838 Conserved hypothetical protein K07056 rsmI; 16S rRNA (cytidine1402-2'-O)-methyltransferase [EC:2.1.1.198] D spr1086 Conserved hypothetical protein K06442 tlyA; 23S rRNA (cytidine1920-2'-O)/16S rRNA (cytidine1409-2'-O)-methyltransferase [EC:2.1.1.226 2.1.1.227] D spr1913 rrmA; 23S rRNA m1G745 methyltransferase K00563 rlmA1; 23S rRNA (guanine745-N1)-methyltransferase [EC:2.1.1.187] D spr1311 trmH; tRNA (guanosine-2'-O-)-methyltransferase, TrmH family K03218 rlmB; 23S rRNA (guanosine2251-2'-O)-methyltransferase [EC:2.1.1.185] D spr2044 Conserved hypothetical protein K00783 rlmH; 23S rRNA (pseudouridine1915-N3)-methyltransferase [EC:2.1.1.177] D spr1236 Conserved hypothetical protein K06969 rlmI; 23S rRNA (cytosine1962-C5)-methyltransferase [EC:2.1.1.191] D spr0676 Conserved hypothetical protein K06941 rlmN; 23S rRNA (adenine2503-C2)-methyltransferase [EC:2.1.1.192] D spr0932 Conserved hypothetical protein K03215 rumA; 23S rRNA (uracil1939-C5)-methyltransferase [EC:2.1.1.190] D spr1689 rluB; Ribosomal large subunit pseudouridine synthase B K06178 rluB; 23S rRNA pseudouridine2605 synthase [EC:5.4.99.22] D spr0830 rluD; 23S rRNA pseudouridine synthase (supresses ftsH(ts) mutants) K06180 rluD; 23S rRNA pseudouridine1911/1915/1917 synthase [EC:5.4.99.23] D spr1824 rluD; Ribosomal large subunit pseudouridine synthase D K06180 rluD; 23S rRNA pseudouridine1911/1915/1917 synthase [EC:5.4.99.23] D spr1006 rluD; 23S rRNA pseudouridine synthase K06180 rluD; 23S rRNA pseudouridine1911/1915/1917 synthase [EC:5.4.99.23] D spr0130 rimI; Ribosomal protein alanine acetyltransferase K03789 rimI; [ribosomal protein S18]-alanine N-acetyltransferase [EC:2.3.1.266] D spr0686 rimM; 16S rRNA processing protein RimM K02860 rimM; 16S rRNA processing protein RimM D spr1608 prmA; Ribosomal protein methyltransferase K02687 prmA; ribosomal protein L11 methyltransferase [EC:2.1.1.-] D spr0176 Conserved hypothetical protein K07447 ruvX; putative pre-16S rRNA nuclease [EC:3.1.-.-] D spr0520 Conserved hypothetical protein K11145 mrnC; mini-ribonuclease III [EC:3.1.26.-] D spr1440 Conserved hypothetical protein K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7] D spr0670 rheB; ATP-dependent RNA helicase K18692 cshB; ATP-dependent RNA helicase CshB [EC:5.6.2.7] D spr1798 Conserved hypothetical protein K06949 rsgA; ribosome biogenesis GTPase / thiamine phosphate phosphatase [EC:3.6.1.- 3.1.3.100] D spr1553 serA; Phosphoglycerate dehydrogenase K03977 engA; GTPase D spr1043 Conserved hypothetical protein K14540 rbgA; ribosome biogenesis GTPase A D spr0589 Conserved hypothetical protein K03665 hflX; GTPase D spr1594 Conserved hypothetical protein K06948 yqeH; 30S ribosome assembly GTPase D spr0926 Conserved hypothetical protein K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87] D spr1487 relA; GTP pyrophosphokinase K01139 spoT; GTP diphosphokinase / guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2] D spr0482 rbfA; Ribosome binding factor A K02834 rbfA; ribosome-binding factor A D spr0477 Conserved hypothetical protein K09748 rimP; ribosome maturation factor RimP D spr2031 Conserved hypothetical protein K14761 rlbA; ribosome-associated protein D spr1589 Conserved hypothetical protein K09710 ybeB; ribosome-associated protein D spr0869 Conserved hypothetical protein K07042 ybeY; probable rRNA maturation factor D spr1593 Conserved hypothetical protein K07574 yhbY; RNA-binding protein D spr2011 Conserved hypothetical protein K05808 hpf; ribosome hibernation promoting factor D spr0004 Conserved hypothetical protein K06942 ychF; ribosome-binding ATPase D spr1158 Conserved hypothetical protein K07040 yceD; DUF177 domain-containing protein C 03016 Transfer RNA biogenesis [BR:spr03016] D spr0591 Conserved hypothetical protein K00784 rnz; ribonuclease Z [EC:3.1.26.11] D spr1413 cca; tRNA nucleotidyltransferase K00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-] D spr0243 proS; Prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15] D spr1502 ileS; Isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5] D spr0235 leuS; Leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D spr0696 metS; Methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] D spr1890 argS; Arginyl-tRNA synthetase(arginine--tRNA ligase) (ARGRS) K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D spr0626 lysS; Lysyl-tRNA synthetase (lysine--tRNA ligase) (LYSRS) K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6] D spr1924 aspS; Aspartyl-tRNA synthetase (aspartate-tRNA ligase) K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12] D spr1240 alaS; Alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7] D spr1397 asnS; Asparaginyl-tRNA synthetase (asparagine--tRNA ligase) K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22] D spr1472 thrS; Threonyl-tRNA synthetase 1 K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3] D spr0372 serS; Seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11] D spr0519 cysS; Cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16] D spr0492 valS; Valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9] D spr1931 hisS; Histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21] D spr0507 pheS; Phenylalanyl-tRNA synthetase alpha chain K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20] D spr0509 pheT; Phenylalanyl-tRNA synthetase beta chain K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20] D spr1910 tyrS; Tyrosyl-tRNA synthetase 1 K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D spr2034 trpS; Tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2] D spr1486 Conserved hypothetical protein K07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96] D spr0458 Conserved hypothetical protein K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-] D spr0476 Conserved hypothetical protein K03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33] D spr1451 truA; tRNA pseudouridine synthase A K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12] D spr1092 truB; tRNA pseudouridine 5S synthase K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25] D spr0783 Probable pyridoxal-phosphate dependent aminotransferase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D spr1001 nifS; Pyridoxal-phosphate dependent aminotransferase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D spr0926 Conserved hypothetical protein K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87] D spr0588 miaA; tRNA isopentenylpyrophosphate transferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75] D spr0920 thdF; Thiophene and furan oxidation protein K03650 mnmE; tRNA modification GTPase [EC:3.6.-.-] D spr0124 gidA; Glucose inhibited division protein A K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme D spr1853 rnpA; Ribonuclease P - protein component K03536 rnpA; ribonuclease P protein component [EC:3.1.26.5] D sprs02 rnpB; Ribonuclease P - RNA component K01978 rnpB; M1 RNA D spr1329 glyQ; Glycyl-tRNA synthetase alpha chain K01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14] D spr1328 glyS; Glycyl-tRNA synthetase beta chain K01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14] D spr1881 gltX; Glutamyl-tRNA synthetase (glutamate--tRNA ligase) K09698 gltX; nondiscriminating glutamyl-tRNA synthetase [EC:6.1.1.24] D spr0888 ebsC; Regulatory protein K03976 ybaK; Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase [EC:3.1.1.-] D spr0022 Conserved hypothetical protein K11991 tadA; tRNA(adenine34) deaminase [EC:3.5.4.33] D spr1994 Conserved hypothetical protein K05540 dusB; tRNA-dihydrouridine synthase B [EC:1.-.-.-] D spr0844 gidA; Glucose inhibited division protein K04094 trmFO; methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase [EC:2.1.1.74] D spr0687 trmD; tRNA (guanine-N1)-methyltransferase K00554 trmD; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228] D spr1463 Conserved hypothetical protein K06967 trmK; tRNA (adenine22-N1)-methyltransferase [EC:2.1.1.217] D spr0432 cspR; rRNA methylase K03216 trmL; tRNA (cytidine/uridine-2'-O-)-methyltransferase [EC:2.1.1.207] D spr1788 yjfA; Possible rRNA/tRNA methylase K03437 spoU; RNA methyltransferase, TrmH family D spr0122 trmU; tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13] D spr1273 queA; S-adenosylmethionine:tRNA ribosyltransferase-isomerase K07568 queA; S-adenosylmethionine:tRNA ribosyltransferase-isomerase [EC:2.4.99.17] D spr1603 Conserved hypothetical protein K09457 queF; 7-cyano-7-deazaguanine reductase [EC:1.7.1.13] D spr1869 tgt; tRNA-guanine transglycosylase (guanine insertion enzyme) K00773 tgt; queuine tRNA-ribosyltransferase [EC:2.4.2.29] D spr0784 thiI; Thiamin biosynthesis protein K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4] D spr0010 Conserved hypothetical protein K04075 tilS; tRNA(Ile)-lysidine synthase [EC:6.3.4.19] D spr0129 Conserved hypothetical protein K14742 tsaB; tRNA threonylcarbamoyladenosine biosynthesis protein TsaB D spr0131 gcp; Secreted metalloendopeptidase Gcp K25706 tsaD; tRNA N6-adenosine threonylcarbamoyltransferase [EC:2.3.1.234] D spr1761 Conserved hypothetical protein K06925 tsaE; tRNA threonylcarbamoyladenosine biosynthesis protein TsaE D spr1587 Conserved hypothetical protein K27343 tmcAL; tRNAmet cytidine acetate ligase [EC:6.3.1.22] D spr0878 rnr; Exoribonuclease R K12573 rnr; ribonuclease R [EC:3.1.13.1] D spr0516 pnpA; Polyribonucleotide nucleotidyltransferase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] C 03012 Translation factors [BR:spr03012] D spr0481 infB; Initiation factor IF2 K02519 infB; translation initiation factor IF-2 D spr0861 infC; Translation initiation factor IF-3 K02520 infC; translation initiation factor IF-3 D spr1021 ABC-NBD; ABC transporter ATP-binding protein - unknown substrate K06158 ABCF3; ATP-binding cassette, subfamily F, member 3 D spr2019 tsf; Elongation factor TS K02357 tsf; elongation factor Ts D spr1343 tufA; Translation elongation factor TU K02358 tuf; elongation factor Tu D spr0250 fusA; Elongation factor G K02355 fusA; elongation factor G D spr0924 prfA; Peptide chain release factor I K02835 prfA; peptide chain release factor 1 D spr0846 frr; Ribosome recycling factor K02838 frr; ribosome recycling factor D spr0925 hemK; HemK protein homolog; possible protoporphyrinogen oxidase K02493 hemK; release factor glutamine methyltransferase [EC:2.1.1.297] D spr0005 pth; Peptidyl-tRNA hydrolase K01056 PTH1; peptidyl-tRNA hydrolase, PTH1 family [EC:3.1.1.29] D spr0211 infA; Translation initiation factor IF-1 K02518 infA; translation initiation factor IF-1 D spr0392 efp; Elongation factor P K02356 efp; elongation factor P D spr0665 prfB; Peptide chain release factor 2 K02836 prfB; peptide chain release factor 2 D spr0396 prfC; Peptide chain release factor 3 K02837 prfC; peptide chain release factor 3 C 03110 Chaperones and folding catalysts [BR:spr03110] D spr2000 Class III stress response-related ATPase, truncation K03696 clpC; ATP-dependent Clp protease ATP-binding subunit ClpC D spr0725 clpE; ATP dependent protease K03697 clpE; ATP-dependent Clp protease ATP-binding subunit ClpE D spr0307 clpL; ATP-dependent protease ATP-binding subunit K04086 clpL; ATP-dependent Clp protease ATP-binding subunit ClpL D spr1427 clpX; ATP-dependent Clp protease ATP-binding subunit (class III heat-shock protein) K03544 clpX; ATP-dependent Clp protease ATP-binding subunit ClpX D spr0455 dnaK; Class I heat-shock protein (molecular chaperone) K04043 dnaK; molecular chaperone DnaK D spr1722 groEL; Chaperonin GroEL K04077 groEL; chaperonin GroEL [EC:5.6.1.7] D spr0456 dnaJ; Heat-shock protein (activation of DnaK) K03686 dnaJ; molecular chaperone DnaJ D spr1993 hsp33; Chaperonin (heat shock protein 33) K04083 hslO; molecular chaperone Hsp33 D spr0454 grpE; Heat-shock protein (activation of DnaK) K03687 GRPE; molecular chaperone GrpE D spr1723 groES; Cochaperonin GroES K04078 groES; chaperonin GroES D spr2045 sphtra; Serine protease K04771 degP; serine protease Do [EC:3.4.21.107] D spr0012 ftsH; Cell-division protein / general stress protein (class III heat-shock) K03798 ftsH; cell division protease FtsH [EC:3.4.24.-] D spr1365 atpB; Proton-translocating ATPase, F0 sector, subunit a K02108 ATPF0A; F-type H+-transporting ATPase subunit a D spr0057 strH; Beta-N-acetyl-hexosaminidase precursor K12373 HEXA_B; hexosaminidase [EC:3.2.1.52] D spr1949 Hypothetical protein K12373 HEXA_B; hexosaminidase [EC:3.2.1.52] D spr0679 ppiA; Peptidyl-prolyl cis-trans isomerase K03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8] D spr1393 Hypothetical protein K03768 PPIB; peptidyl-prolyl cis-trans isomerase B (cyclophilin B) [EC:5.2.1.8] D spr0884 ppmA; Proteinase maturation protein K07533 prsA; foldase protein PrsA [EC:5.2.1.8] D spr1602 trxA; Thioredoxin reductase K03671 TXN; thioredoxin C 04131 Membrane trafficking [BR:spr04131] D spr1775 ndk; Nucleoside diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6] D spr1951 Conserved hypothetical protein K01191 MAN2C1; alpha-mannosidase [EC:3.2.1.24] D spr1825 gapA; Glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] D spr1499 gpmA; Phosphoglyceromutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] D spr0797 pykF; Pyruvate kinase I; fructose-stimulated K00873 PK; pyruvate kinase [EC:2.7.1.40] C 04121 Ubiquitin system C 03051 Proteasome C 03032 DNA replication proteins [BR:spr03032] D spr1020 hlpA; Histone-like DNA-binding protein K03530 hupB; DNA-binding protein HU-beta D spr0001 dnaA; DNA biosynthesis, initiation, binding protein K02313 dnaA; chromosomal replication initiator protein D spr2008 dnaC; Replicative DNA helicase K02314 dnaB; replicative DNA helicase [EC:5.6.2.3] D spr0978 dnaG; DNA primase K02316 dnaG; DNA primase [EC:2.7.7.101] D spr1556 dnaB; Chromosome replication initiation protein/membrane attachment protein, Putative K03346 dnaB; replication initiation and membrane attachment protein D spr1555 dnaI; Primosome component (helicase loader) K11144 dnaI; primosomal protein DnaI D spr1395 ssbA; Single stranded binding protein K03111 ssb; single-strand DNA-binding protein D spr1724 ssbB; Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein D spr0795 dnaE; DNA-polymerase III alpha-chain K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] D spr0251 polC; DNA polymerase III, alpha subunit K03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7] D spr0002 dnaN; DNA biosynthesis; sliding clamp subunit, required for high processivity; DNA polymerase III beta-subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] D spr0673 holA; DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] D spr0836 holB; DNA polymerase III, delta' subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7] D spr0896 dnaQ; DNA polymerase III, epsilon chain K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] D spr0769 dnaX; DNA-directed DNA polymerase III chain K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D spr1044 rnh; Ribonuclease H K03470 rnhB; ribonuclease HII [EC:3.1.26.4] D spr0365 rnhB; Ribonuclease HII K03471 rnhC; ribonuclease HIII [EC:3.1.26.4] D spr0032 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] D spr1024 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] D spr1099 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2] D spr0715 gyrB; DNA gyrase K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2] D spr0757 parC; Topoisomerase IV subunit A K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2] D spr0756 parE; Topoisomerase IV subunit B K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2] D spr1141 topA; DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1] C 03036 Chromosome and associated proteins [BR:spr03036] D spr1127 rncS; Ribonuclease III K03685 rnc; ribonuclease III [EC:3.1.26.3] D spr1020 hlpA; Histone-like DNA-binding protein K03530 hupB; DNA-binding protein HU-beta D spr0001 dnaA; DNA biosynthesis, initiation, binding protein K02313 dnaA; chromosomal replication initiator protein D spr1430 dpr; DNA binding protein starved cells-like peroxide resistance protein K04047 dps; starvation-inducible DNA-binding protein D spr1126 smc; chromosome condensation and segregation SMC protein K03529 smc; chromosome segregation protein D spr1691 Conserved hypothetical protein K05896 scpA; segregation and condensation protein A D spr1690 Conserved hypothetical protein K06024 scpB; segregation and condensation protein B D spr1511 ftsA; Cell division protein FtsA K03590 ftsA; cell division protein FtsA D spr0008 Hypothetical protein K13052 divIC; cell division protein DivIC D spr0666 ftsE; ABC transporter ATP-binding protein & cell division protein K09812 ftsE; cell division transport system ATP-binding protein D spr0781 ftsK; Cell division protein K03466 ftsK; DNA segregation ATPase FtsK/SpoIIIE, S-DNA-T family D spr0303 ftsL; Cell division protein K03586 ftsL; cell division protein FtsL D spr0605 divIB; Cell division protein DivIB K03589 ftsQ; cell division protein FtsQ D spr0973 ftsW; Cell division protein FtsW K03588 ftsW; cell division protein FtsW D spr0667 ftsX; Cell division protein FtsX K09811 ftsX; cell division transport system permease protein D spr1510 ftsZ; Cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ D spr0716 ezrA; Cell division regulator, negative regulator of FtsZ ring formation K06286 ezrA; septation ring formation regulator D spr1505 divIVA; Cell-division initiation protein (septum placement) K04074 divIVA; cell division initiation protein D spr1508 Conserved hypothetical protein K09772 sepF; cell division inhibitor SepF D spr2023 mreC; Cell shape determining protein MreC K03570 mreC; rod shape-determining protein MreC D spr2022 mreD; Cell-shape determining protein MreD K03571 mreD; rod shape-determining protein MreD D spr0712 rodA; Rod shape determining protein K05837 rodA; rod shape determining protein RodA D spr2046 spo0J; Chromosome segregation protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein D spr0757 parC; Topoisomerase IV subunit A K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2] D spr0756 parE; Topoisomerase IV subunit B K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2] D spr0124 gidA; Glucose inhibited division protein A K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme D spr1164 gidB; Glucose inhibited division protein B K03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170] D spr0844 gidA; Glucose inhibited division protein K04094 trmFO; methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase [EC:2.1.1.74] D spr0494 Hypothetical protein K04095 fic; cell filamentation protein, protein adenylyltransferase [EC:2.7.7.108] D spr1426 Conserved hypothetical protein K03978 engB; GTP-binding protein D spr1422 Conserved hypothetical protein K09762 whiA; cell division protein WhiA C 03400 DNA repair and recombination proteins [BR:spr03400] D spr1317 ogt; O6-methylguanine-DNA methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63] D spr1055 ung; DNA-uracil glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27] D spr1108 mutY; Similar to A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31] D spr1157 nth; endonuclease III (DNA repair) K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] D spr1054 mutX; 8-oxodGTP nucleoside triphosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D spr0650 Conserved hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D spr1115 Conserved hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D spr0721 Conserved hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D spr1609 mutT; 7,8-dihydro-8-oxoguanine-triphosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D spr0023 dut; Deoxyuridinetriphosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23] D spr0166 tag; 3-Methyladenine DNA glycosylase I, constitutive K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20] D spr0872 mutM; Formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18] D spr1660 exoA; Exodeoxyribonuclease K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2] D spr0537 recJ; Single-stranded DNA-specific exonuclease, 5'-3' K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D spr1024 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] D spr0032 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] D spr0171 uvrA; Excinuclease ABC - subunit A K03701 uvrA; excinuclease ABC subunit A D spr1118 uvrB; Exonuclease ABC - subunit B K03702 uvrB; excinuclease ABC subunit B D spr0543 uvrC; Exonuclease ABC - subunit C K03703 uvrC; excinuclease ABC subunit C D spr0995 pcrA; ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] D spr1777 rpoB; DNA-dependent RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6] D spr1776 rpoC; DNA-dependent RNA polymerase K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] D spr0215 rpoA; RNA polymerase alpha subunit K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6] D spr0437 rpoE; RNA polymerase (delta subunit) K03048 rpoE; DNA-directed RNA polymerase subunit delta D spr1582 Hypothetical protein K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6] D spr0006 mfd; Transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4] D spr1888 hexA; DNA mismatch repair protein HexA K03555 mutS; DNA mismatch repair protein MutS D spr0368 mutS2; DNA mismatch repair protein K07456 mutS2; DNA mismatch repair protein MutS2 D spr0160 hexB; DNA mismatch repair protein K03572 mutL; DNA mismatch repair protein MutL D spr1089 xseA; Exodeoxyribonuclease large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6] D spr1088 xseB; Exodeoxyribonuclease small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6] D spr0795 dnaE; DNA-polymerase III alpha-chain K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] D spr0251 polC; DNA polymerase III, alpha subunit K03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7] D spr0002 dnaN; DNA biosynthesis; sliding clamp subunit, required for high processivity; DNA polymerase III beta-subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] D spr0673 holA; DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] D spr0836 holB; DNA polymerase III, delta' subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7] D spr0896 dnaQ; DNA polymerase III, epsilon chain K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] D spr0769 dnaX; DNA-directed DNA polymerase III chain K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D spr1395 ssbA; Single stranded binding protein K03111 ssb; single-strand DNA-binding protein D spr1724 ssbB; Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein D spr0363 recD; Exonuclease V K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5] D spr1757 recA; DNA recombination/repair K03553 recA; recombination protein RecA D spr0165 ruvA; Holliday junction DNA helicase K03550 ruvA; holliday junction DNA helicase RuvA D spr0238 ruvB; Branch migration of Holliday structures K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4] D spr1581 priA; Primosomal replication factor Y K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4] D spr0025 radA; DNA repair: sensitivity to gamma and UV radiation K04485 radA; DNA repair protein RadA/Sms D spr2032 recF; Recombination protein RecF K03629 recF; DNA replication and repair protein RecF D spr1539 recG; Branch migration of Holliday junctions, junction-specific DNA helicase K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4] D spr0036 Conserved hypothetical protein K03584 recO; DNA repair protein RecO (recombination protein O) D spr1516 recR; Recombination protein RecR K06187 recR; recombination protein RecR D spr1084 recN; DNA repair and genetic recombination K03631 recN; DNA repair protein RecN (Recombination protein N) D spr0330 recU; Recombination protein U K03700 recU; recombination protein U D spr1040 rexA; First subunit of major exonuclease K16898 addA; ATP-dependent helicase/nuclease subunit A [EC:5.6.2.4 3.1.-.-] D spr1039 rexB; Second subunit of major exonuclease K16899 addB; ATP-dependent helicase/nuclease subunit B [EC:5.6.2.4 3.1.-.-] D spr1099 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2] D spr0715 gyrB; DNA gyrase K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2] D spr1141 topA; DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1] D spr1020 hlpA; Histone-like DNA-binding protein K03530 hupB; DNA-binding protein HU-beta D spr0414 dinP; DNA-damage-inducible protein P K02346 dinB; DNA polymerase IV [EC:2.7.7.7] D spr1718 Conserved hypothetical protein K03565 recX; regulatory protein D spr0711 dinG; ATP-dependent DNA helicase K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3] D spr1065 nrdE; Ribonucleoside-diphosphate reductase (major subunit) K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D spr1066 nrdF; Nonessential ribonucleoside-diP reductase 2, subunit beta, class I, function unknown K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1] D spr1176 Conserved hypothetical protein K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3] C 03029 Mitochondrial biogenesis [BR:spr03029] D spr0481 infB; Initiation factor IF2 K02519 infB; translation initiation factor IF-2 D spr0861 infC; Translation initiation factor IF-3 K02520 infC; translation initiation factor IF-3 D spr2019 tsf; Elongation factor TS K02357 tsf; elongation factor Ts D spr1343 tufA; Translation elongation factor TU K02358 tuf; elongation factor Tu D spr0250 fusA; Elongation factor G K02355 fusA; elongation factor G D spr0871 era; GTPase/GTP-binding protein K03595 era; GTPase D spr1910 tyrS; Tyrosyl-tRNA synthetase 1 K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D spr0235 leuS; Leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D spr1924 aspS; Aspartyl-tRNA synthetase (aspartate-tRNA ligase) K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12] D spr1890 argS; Arginyl-tRNA synthetase(arginine--tRNA ligase) (ARGRS) K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D spr0394 gatA; Glu-tRNAGln amidotransferase subunit A K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7] D spr0393 gatB; Glutamyl tRNA-Gln amidotransferase subunit B K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7] D spr0395 gatC; Glutamyl tRNA-Gln amidotransferase, subunit C K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7] D spr1395 ssbA; Single stranded binding protein K03111 ssb; single-strand DNA-binding protein D spr1724 ssbB; Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein D spr0455 dnaK; Class I heat-shock protein (molecular chaperone) K04043 dnaK; molecular chaperone DnaK D spr0454 grpE; Heat-shock protein (activation of DnaK) K03687 GRPE; molecular chaperone GrpE D spr1722 groEL; Chaperonin GroEL K04077 groEL; chaperonin GroEL [EC:5.6.1.7] D spr1723 groES; Cochaperonin GroES K04078 groES; chaperonin GroES D spr0456 dnaJ; Heat-shock protein (activation of DnaK) K03686 dnaJ; molecular chaperone DnaJ D spr0783 Probable pyridoxal-phosphate dependent aminotransferase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D spr1001 nifS; Pyridoxal-phosphate dependent aminotransferase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D spr1852 Conserved hypothetical protein K03217 yidC; YidC/Oxa1 family membrane protein insertase D spr1790 Conserved hypothetical protein K03217 yidC; YidC/Oxa1 family membrane protein insertase B B 09183 Protein families: signaling and cellular processes C 02000 Transporters [BR:spr02000] D spr1289 ABC-N_P; ABC transporter ATP-binding/membrane-spanning protein - unknown substrate K14698 irtA; ATP-binding cassette, subfamily B, bacterial IrtA/YbtP [EC:7.-.-.-] D spr1290 ABC-N_P; ABC transporter ATP-binding/membrane-spanning protein - unknown substrate K14699 irtB; ATP-binding cassette, subfamily B, bacterial IrtB/YbtQ [EC:7.-.-.-] D spr1657 ABC-N_P; ABC transporter ATP-binding/membrane spanning protein - unknown substrate K18889 mdlA; ATP-binding cassette, subfamily B, multidrug efflux pump D spr1656 ABC-N_P; ABC transporter ATP-binding/membrane spanning protein - unknown substrate K18890 mdlB; ATP-binding cassette, subfamily B, multidrug efflux pump D spr1887 ABC-NP; ABC transporter ATP-binding/membrane spanning protein - unknown substrate K18891 patA; ATP-binding cassette, subfamily B, multidrug efflux pump D spr1885 ABC-NP; ABC transporter ATP-binding/membrane spanning protein - unknown substrate K18892 patB; ATP-binding cassette, subfamily B, multidrug efflux pump D spr1216 ABC-N_P; ABC transporter ATP-binding/membrane-spanning protein - unknown substrate K18887 efrA; ATP-binding cassette, subfamily B, multidrug efflux pump D spr1215 ABC-N_P; ABC transporter ATP-binding/membrane-spanning protein - unknown substrate K18888 efrB; ATP-binding cassette, subfamily B, multidrug efflux pump D spr1183 ABC transporter ATP-bindng protein - possibly multidrug efflux, truncation K06147 ABCB-BAC; ATP-binding cassette, subfamily B, bacterial D spr1734 ABC transporter ATP-binding protein - unknown substrate, truncation K06147 ABCB-BAC; ATP-binding cassette, subfamily B, bacterial D spr0043 comA; Transport ATP-binding protein ComA K12292 comA; ATP-binding cassette, subfamily C, bacterial, competence factor transporting protein [EC:3.4.22.-] D spr0106 Transporter, truncation K20344 blpA; ATP-binding cassette, subfamily C, bacteriocin exporter D spr1412 ABC-NBD; ABC transporter ATP-binding protein - unknown substrate K15738 uup; ABC transport system ATP-binding/permease protein D spr1645 ABC-SBP; ABC transporter substrate-binding protein - unknown substrate K02012 afuA; iron(III) transport system substrate-binding protein D spr1643 ABC-MSP; ABC transporter membrane-spanning permease - unknown substrate K02011 afuB; iron(III) transport system permease protein D spr0220 ABC-MSP; ABC transporter membrane-spanning permease - iron transport K02011 afuB; iron(III) transport system permease protein D spr0221 ABC-MSP; ABC transporter membrane-spanning permease - iron transport K02011 afuB; iron(III) transport system permease protein D spr1644 ABC-NBD; ABC transporter ATP-binding protein - unknown substrate K02010 afuC; iron(III) transport system ATP-binding protein [EC:7.2.2.7] D spr0222 ABC-NBD; ABC transporter ATP-binding protein - iron transport K02010 afuC; iron(III) transport system ATP-binding protein [EC:7.2.2.7] D spr1243 potD; ABC transporter substrate-binding protein - spermidine/putrescine transport K11069 potD; spermidine/putrescine transport system substrate-binding protein D spr1244 potC; ABC transporter membrane-spanning permease - spermidine/putrescine transport K11070 potC; spermidine/putrescine transport system permease protein D spr1245 potB; ABC transporter membrane-spanning permease - spermidine/putrescine transport K11071 potB; spermidine/putrescine transport system permease protein D spr1246 potA; ABC transporter ATP-binding protein - spermidine/putrescine transport K11072 potA; spermidine/putrescine transport system ATP-binding protein [EC:7.6.2.11] D spr1677 proWX; ABC transporter membrane-spanning permease - choline transporter K05845 opuC; osmoprotectant transport system substrate-binding protein D spr1678 proV; ABC transporter ATP-binding protein - choline transporter K05847 opuA; osmoprotectant transport system ATP-binding protein [EC:7.6.2.9] D spr1437 msmK; ABC transporter ATP-binding protein - multiple sugar transport K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-] D spr1918 malX; ABC transporter substrate-binding protein - maltose/maltodextrin K15770 cycB; arabinogalactan oligomer / maltooligosaccharide transport system substrate-binding protein D spr1919 malC; ABC transporter membrane-spanning permease - maltose/maltodextrin K15771 ganP; arabinogalactan oligomer / maltooligosaccharide transport system permease protein D spr1920 malD; ABC transporter membrane-spanning permease - maltose/maltodextrin K15772 ganQ; arabinogalactan oligomer / maltooligosaccharide transport system permease protein D spr1712 msmE; ABC transporter substrate-binding protein - multiple sugars K10117 msmE; raffinose/stachyose/melibiose transport system substrate-binding protein D spr1711 msmF; ABC transporter membrane-spanning permease - multiple sugars K10118 msmF; raffinose/stachyose/melibiose transport system permease protein D spr1710 msmG; ABC transporter membrane spanning permease - multiple sugars K10119 msmG; raffinose/stachyose/melibiose transport system permease protein D spr0083 ABC-SBP; ABC transporter solute binding protein - sugar transport K17318 lplA; putative aldouronate transport system substrate-binding protein D spr0081 ABC-MSP; ABC transporter membrane-spanning permease - sugar transport K17319 lplB; putative aldouronate transport system permease protein D spr0082 ABC-MSP; ABC transporter membrane spanning permease - sugar transport K17320 lplC; putative aldouronate transport system permease protein D spr1620 ABC-SBP; ABC transporter substrate-binding protein - sugar transport K10120 msmE; fructooligosaccharide transport system substrate-binding protein D spr1619 ABC-MSP; ABC transporter membrane-spanning permease - sugar transporter K10121 msmF; fructooligosaccharide transport system permease protein D spr1618 ABC-MSP; ABC transporter membrane-spanning permease - sugar transport K10122 msmG; fructooligosaccharide transport system permease protein D spr0747 Conserved hypothetical protein K07335 bmpA; basic membrane protein A and related proteins D spr0749 ABC-MSP; ABC transporter membrane-spanning permease - ribose/galactose transport K23535 nupB; general nucleoside transport system permease protein D spr0750 ABC-MSP; ABC transporter membrane-spanning permease - ribose/galactose transport K23536 nupC; general nucleoside transport system permease protein D spr0748 ABC-NBD; ABC transporter ATP-binding protein - ribose/galactose transport K23537 nupA; general nucleoside transport system ATP-binding protein D spr1527 ABC-SBP; ABC transporter substrate-binding protein - sugar transport K02027 ABC.MS.S; multiple sugar transport system substrate-binding protein D spr1534 ABC-SBP; ABC transporter substrate-binding protein - sugar transport K02027 ABC.MS.S; multiple sugar transport system substrate-binding protein D spr1526 ABC-MSP; ABC transporter membrane-spanning permease - sugar transport K02025 ABC.MS.P; multiple sugar transport system permease protein D spr1533 ABC-MSP; ABC transporter membrane-spanning permease - sugar transport K02025 ABC.MS.P; multiple sugar transport system permease protein D spr1525 ABC-MSP; ABC transporter membrane-spanning permease - sugar transport K02026 ABC.MS.P1; multiple sugar transport system permease protein D spr1532 ABC-MSP; ABC transporter membrane-spanning permease - sugar transport K02026 ABC.MS.P1; multiple sugar transport system permease protein D spr1257 pstS; ABC transporter substrate-binding protein - phosphate transport K02040 pstS; phosphate transport system substrate-binding protein D spr1895 pstS; ABC transporter substrate-binding protein - phosphate transport K02040 pstS; phosphate transport system substrate-binding protein D spr1256 pstC; ABC transporter membrane-spanning permease - phosphate transport K02037 pstC; phosphate transport system permease protein D spr1896 pstC; ABC transporter membrane-spanning permease - phosphate transport K02037 pstC; phosphate transport system permease protein D spr1255 pstA; ABC transporter membrane-spanning permease - phosphate transport K02038 pstA; phosphate transport system permease protein D spr1897 pstA; ABC transporter membrane-spanning permease - phosphate transport K02038 pstA; phosphate transport system permease protein D spr1253 pstB; ABC transporter ATP-binding protein - phosphate transport K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1] D spr1254 pstB; ABC transporter ATP-binding protein - phosphate transport K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1] D spr1898 pstB; ABC transporter ATP-binding protein - phosphate transport K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1] D spr1120 glnP; ABC transporter membrane spanning permease - glutamine transport K10036 glnH; glutamine transport system substrate-binding protein D spr1121 glnQ; ABC transporter ATP-binding protein - glutamine transport K10038 glnQ; glutamine transport system ATP-binding protein [EC:7.4.2.1] D spr0534 glnH; ABC transporter substrate-binding protein - glutamine transport/Major cell binding factor precursor K10039 peb1A; aspartate/glutamate/glutamine transport system substrate-binding protein D spr0533 glnP; ABC transporter membrane-spanning permease - glutamine transport K10040 peb1B; aspartate/glutamate/glutamine transport system permease protein D spr0532 glnP; ABC transporter membrane-spanning permease - glutamine transport K10040 peb1B; aspartate/glutamate/glutamine transport system permease protein D spr0146 ABC-SBP; ABC transporter substrate-binding protein - amino acid transport K02424 tcyA; L-cystine transport system substrate-binding protein D spr1315 ABC-MSP; ABC transporter membrane-spanning permease - aspartate/glutamate transport K10009 tcyB; L-cystine transport system permease protein D spr1314 ABC-NDB; ABC transporter ATP-binding protein - aspartate/glutamate transport K10010 tcyC; L-cystine transport system ATP-binding protein [EC:7.4.2.1] D spr1251 glnH; ABC transporter substrate-binding protein - glutamine-binding protein K23059 artP; arginine/lysine/histidine transporter system substrate-binding protein D spr0727 glnP; ABC transporter membrane-spanning permease - glutamine transport K17077 artQ; arginine/lysine/histidine transport system permease protein D spr0728 glnQ; ABC transporter ATP-binding protein - glutamine transport K23060 artR; arginine/lysine/histidine transport system ATP-binding protein [EC:7.4.2.1] D spr0659 livJ; ABC transporter substrate-binding protein - branched chain amino acid transport K01999 livK; branched-chain amino acid transport system substrate-binding protein D spr0660 livH; ABC transporter membrane-spanning permease - branched chain amino acid transport K01997 livH; branched-chain amino acid transport system permease protein D spr0661 livM; ABC transporter membrane-spanning permease - branched chain amino acid transport K01998 livM; branched-chain amino acid transport system permease protein D spr0662 livG; ABC transporter ATP-binding protein - branched chain amino acid transport K01995 livG; branched-chain amino acid transport system ATP-binding protein D spr0663 livF; ABC transporter ATP-binding protein - branched chain amino acid transport K01996 livF; branched-chain amino acid transport system ATP-binding protein D spr0147 ABC-SBP; ABC transporter solute-binding protein - unknown substrate K02073 metQ; D-methionine transport system substrate-binding protein D spr0150 ABC-MSD; ABC transporter membrane-spanning permease - unknown substrate K02072 metI; D-methionine transport system permease protein D spr0149 ABC-NBD; ABC transporter ATP-binding protein - unknown substrate K02071 metN; D-methionine transport system ATP-binding protein D spr0975 ABC-SBP; ABC transporter substrate-binding protein - unknown substrate K01989 K01989; putative tryptophan/tyrosine transport system substrate-binding protein D spr0976 ABC-MSP; ABC transporter membrane-spanning permease - unknown substrate K05832 K05832; putative tryptophan/tyrosine transport system permease protein D spr0977 ABC-NBD; ABC transporter ATP-binding protein - unknown substrate K05833 K05833; putative tryptophan/tyrosine transport system ATP-binding protein D spr0409 glnH; ABC transporter substrate binding protein - glutamine transport K17073 lysX1; putative lysine transport system substrate-binding protein D spr0408 glnQ; ABC transporter ATP-binding protein - glutamine K17076 lysY; putative lysine transport system ATP-binding protein D spr1353 glnH; ABC transporter substrate-binding protein - glutamine transport K02030 ABC.PA.S; polar amino acid transport system substrate-binding protein D spr0545 ABC-SBP; ABC transporter substrate-binding protein - glutamine transport/Major cell binding factor precursor K02030 ABC.PA.S; polar amino acid transport system substrate-binding protein D spr0101 ABC-SBP; ABC transporter solute-binding protein - amino acid transport K02030 ABC.PA.S; polar amino acid transport system substrate-binding protein D spr1355 glnP; ABC transporter membrane-spanning permease - glutamine transport K02029 ABC.PA.P; polar amino acid transport system permease protein D spr0624 glnP; ABC transporter membrane-spanning permease - glutamine transport K02029 ABC.PA.P; polar amino acid transport system permease protein D spr0623 glnP; ABC transporter membrane-spanning permease - glutamine transport K02029 ABC.PA.P; polar amino acid transport system permease protein D spr1354 glnQ; ABC transporter ATP-binding protein - glutamine transport K02028 ABC.PA.A; polar amino acid transport system ATP-binding protein [EC:7.4.2.1] D spr0622 glnQ; ABC transporter ATP-binding protein - glutamine transport K02028 ABC.PA.A; polar amino acid transport system ATP-binding protein [EC:7.4.2.1] D spr1382 aliB; ABC transporter substrate-binding protein - oligopeptide transport K15580 oppA; oligopeptide transport system substrate-binding protein D spr1707 amiA; ABC transporter substrate-binding protein - oligopeptide transport K15580 oppA; oligopeptide transport system substrate-binding protein D spr1706 amiC; ABC transporter membrane-spanning permease - oligopeptide transport K15581 oppB; oligopeptide transport system permease protein D spr1705 amiD; ABC transporter membrane-spanning permease - oligopeptide transport K15582 oppC; oligopeptide transport system permease protein D spr1704 amiE; ABC transporter ATP-binding protein - oligopeptide transport K15583 oppD; oligopeptide transport system ATP-binding protein D spr1703 amiF; ABC transporter ATP-binding protein - oligopeptide transport K10823 oppF; oligopeptide transport system ATP-binding protein D spr1194 appA; ABC transporter substrate-binding protein - oligopeptide transport K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein D spr0327 aliA; ABC transporter substrate-binding protein - oligopeptide transport K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein D spr1193 appB; ABC transporter membrane-spanning permease - oligopeptide transport K02033 ABC.PE.P; peptide/nickel transport system permease protein D spr1192 appC; ABC transporter membrane-spanning permease - oligopeptide transport K02034 ABC.PE.P1; peptide/nickel transport system permease protein D spr1191 appD; ABC transporter ATP-binding protein - oligopeptide transport K02031 ddpD; peptide/nickel transport system ATP-binding protein D spr0934 ABC-SBP; ABC transporter substrate-binding protein - iron transport K25286 fagD; iron-siderophore transport system substrate-binding protein D spr0935 ABC-MSP; ABC transporter membrane-spanning permease - iron transport K23186 fepD; iron-siderophore transport system permease protein D spr0936 ABC-MSP; ABC transporter membrane-spanning permease - iron transport K23187 fepG; iron-siderophore transport system permease protein D spr0938 ABC-NBD; ABC transporter ATP-binding protein - iron transport K23188 fepC; iron-siderophore transport system ATP-binding protein [EC:7.2.2.17 7.2.2.-] D spr1687 fatB; ABC transporter substrate-binding protein - ferric iron transport K25282 yclQ; iron-siderophore transport system substrate-binding protein D spr1685 fatC; ABC transporter membrane-spanning permease - ferric iron transport K25283 yclO; iron-siderophore transport system permease protein D spr1684 fatD; ABC transporter membrane-spanning permease - ferric iron transport K25284 yclN; iron-siderophore transport system permease protein D spr1686 fecE; ABC transporter ATP-binding protein - ferric iron transport K25285 yclP; iron-siderophore transport system ATP-binding protein [EC:7.2.2.-] D spr0906 lmb; Lipoprotein K09815 znuA; zinc transport system substrate-binding protein D spr1975 adcA; ABC transporter substrate-binding protein - Zinc (Zn2+) transport K09815 znuA; zinc transport system substrate-binding protein D spr1976 adcB; ABC transporter membrane-spanning permease - Zinc (Zn2+) transport K09816 znuB; zinc transport system permease protein D spr1977 adcC; ABC transporter ATP-binding domain - Zinc (Zn2+) permease K09817 znuC; zinc transport system ATP-binding protein [EC:7.2.2.20] D spr1494 psaA; ABC transporter substrate-binding protein - manganese transport K19971 psaA; manganese/zinc transport system substrate-binding protein D spr1493 psaC; ABC transporter membrane-spanning permease - manganese transport K19972 psaC; manganese/zinc transport system permease protein D spr1492 psaB; ABC transporter ATP-binding protein - manganese transport K10830 psaB; manganese/zinc transport system ATP-binding protein [EC:7.2.2.5] D spr0691 bioY; Biotin synthase K03523 bioY; biotin transport system substrate-specific component D spr0429 Conserved hypothetical protein K16924 mtsT; energy-coupling factor transport system substrate-specific component D spr1291 Hypothetical protein K16926 htsT; energy-coupling factor transport system substrate-specific component D spr0151 Hypothetical protein K16926 htsT; energy-coupling factor transport system substrate-specific component D spr0431 ABC-MSD; ABC transporter membrane-spanning permease - unknown substrate K16785 ecfT; energy-coupling factor transport system permease protein D spr2024 ABC-MSP; ABC transporter membrane-spanning permease - unknown substrate K16785 ecfT; energy-coupling factor transport system permease protein D spr0633 Conserved hypothetical protein K16785 ecfT; energy-coupling factor transport system permease protein D spr1292 Conserved hypothetical protein K16785 ecfT; energy-coupling factor transport system permease protein D spr2026 stpA; ABC transporter ATP-binding protein - unknown substrate K16786 ecfA1; energy-coupling factor transport system ATP-binding protein [EC:7.-.-.-] D spr2025 ABC-NBP; ABC transporter ATP-binding protein - unknown substrate K16787 ecfA2; energy-coupling factor transport system ATP-binding protein [EC:7.-.-.-] D spr0430 ABC-NBD; ABC transporter ATP-binding protein - cobalt transport K01552 ecfA; energy-coupling factor transport system ATP-binding protein [EC:7.-.-.-] D spr0632 ABC-NBD; ABC transporter ATP-binding protein - cobalt or other cation transport K01552 ecfA; energy-coupling factor transport system ATP-binding protein [EC:7.-.-.-] D spr1293 ABC-NBD; ABC transporter ATP-binding protein - unknown substrate K01552 ecfA; energy-coupling factor transport system ATP-binding protein [EC:7.-.-.-] D spr0631 Conserved hypothetical protein K16925 ykoE; energy-coupling factor transport system permease protein D spr0813 ABC-MSD; ABC transporter membrane-spanning permease - unknown substrate K19084 braE; bacitracin transport system permease protein D spr0812 ABC-NBD; ABC transporter ATP-binding protein - unknown substrate K19083 braD; bacitracin transport system ATP-binding protein D spr0695 Conserved hypothetical protein K24948 yknZ; antimicrobial peptide resistance transport system permease protein D spr0694 ABC-NBD; ABC transporter ATP-binding protein - unknown substrate K24949 yknY; antimicrobial peptide resistance transport system ATP-binding protein [EC:7.6.2.-] D spr0667 ftsX; Cell division protein FtsX K09811 ftsX; cell division transport system permease protein D spr0666 ftsE; ABC transporter ATP-binding protein & cell division protein K09812 ftsE; cell division transport system ATP-binding protein D spr0559 Conserved hypothetical protein K25154 evrC; viologen exporter family transport system permease protein D spr0558 Conserved hypothetical protein K25155 evrB; viologen exporter family transport system permease protein D spr0557 ABC-NBD; ABC transporter ATP-binding protein - role in polysaccharide efflux K25156 evrA; viologen exporter family transport system ATP-binding protein D spr0460 ABC-MSP; ABC transporter membrane-spanning permease - unknown substrate K25157 ecsB; ABC-2 type transport system permease protein D spr0459 ABC-NBD; ABC transporter ATP-binding protein - unknown substrate K25158 ecsA; ABC-2 type transport system ATP-binding protein D spr0611 Hypothetical protein K01992 ABC-2.P; ABC-2 type transport system permease protein D spr1237 Hypothetical protein K01992 ABC-2.P; ABC-2 type transport system permease protein D spr0860 Hypothetical protein K01992 ABC-2.P; ABC-2 type transport system permease protein D spr1561 natB; ABC transporter membrane-spanning permease - Na+ export K01992 ABC-2.P; ABC-2 type transport system permease protein D spr1280 Hypothetical protein K01992 ABC-2.P; ABC-2 type transport system permease protein D spr1816 Conserved hypothetical protein K01992 ABC-2.P; ABC-2 type transport system permease protein D spr1238 ABC-NBD; ABC transporter ATP-binding protein - unknown substrate K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D spr1559 ABC-NBD; ABC transporter ATP-binding protein - unknown substrate K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D spr1560 Hypothetical protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D spr1562 natA; ABC transporter ATP-binding protein - Na+ export K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D spr0619 ABC-NBD; ABC transporter ATP-binding protein - unknown substrate K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D spr1281 ABC-NBD; ABC transporter ATP-binding protein - multidrug efflux K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D spr1546 ABC-NBD; ABC transporter ATP-binding protein - unknown substrate K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D spr1817 ABC-NBD; ABC transporter ATP binding protein - unknown substrate K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D spr0610 ABC transporter ATP-binding protein - unknown substrate, truncation K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D spr0859 Hypothetical protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein D spr1496 Hypothetical protein K02004 ABC.CD.P; putative ABC transport system permease protein D spr0524 vex1; ABC transporter membrane-spanning permease - Pep export K02004 ABC.CD.P; putative ABC transport system permease protein D spr0526 vex3; ABC transporter membrane-spanning permease - Pep export K02004 ABC.CD.P; putative ABC transport system permease protein D spr0601 Conserved hypothetical protein K02004 ABC.CD.P; putative ABC transport system permease protein D spr1802 Conserved hypothetical protein K02004 ABC.CD.P; putative ABC transport system permease protein D spr1826 Conserved hypothetical protein K02004 ABC.CD.P; putative ABC transport system permease protein D spr1202 ABC-NDB; ABC transporter ATP-binding protein - unknown substrate K02003 ABC.CD.A; putative ABC transport system ATP-binding protein D spr1497 ABC-NBD; ABC transporter ATP-binding protein - unknown substrate K02003 ABC.CD.A; putative ABC transport system ATP-binding protein D spr0100 ABC-NBD; ABC transporter ATP-binding protein - amino acid transport K02003 ABC.CD.A; putative ABC transport system ATP-binding protein D spr1773 ABC-NBD; ABC transporter ATP-binding protein - unknown substrate K02003 ABC.CD.A; putative ABC transport system ATP-binding protein D spr1801 ABC-NBD; ABC transporter ATP-binding protein - unknown substrate K02003 ABC.CD.A; putative ABC transport system ATP-binding protein D spr0525 vex2; ABC transporter ATP-binding protein - Pep export K02003 ABC.CD.A; putative ABC transport system ATP-binding protein D spr0602 ABC-NBD; ABC transporter ATP-binding protein - sodium transport K02003 ABC.CD.A; putative ABC transport system ATP-binding protein D spr0771 ABC-NBD; ABC transporter ATP-binding protein - unknown substrate K09013 sufC; Fe-S cluster assembly ATP-binding protein D spr1052 Conserved hypothetical protein K26939 norM; MATE family, multidrug efflux pump D spr1756 dinF; DNA-damage-inducible protein K26937 dinF; MATE family, multidrug efflux pump D spr1877 Multi antimicrobial extrusion (MATE) family transporter K26937 dinF; MATE family, multidrug efflux pump D spr1441 oxlT; Major facilitator:Oxalate:Formate Antiporter K08177 oxlT; MFS transporter, OFA family, oxalate/formate antiporter D spr0090 Conserved hypothetical protein K03449 MFS.CP; MFS transporter, CP family, cyanate transporter D spr0875 pmrA; Major facilitator superfamily multi-drug resistance efflux pump K08161 mdtG; MFS transporter, DHA1 family, multidrug resistance protein D spr1062 ptsI; PTS enzyme I K08483 ptsI; phosphoenolpyruvate-protein phosphotransferase (PTS system enzyme I) [EC:2.7.3.9] D spr1063 ptsH; Histidine-containing phosphocarrier protein of the PTS K02784 ptsH; phosphocarrier protein HPr D spr1528 PTS-EII; Phosphotransferase system sugar-specific EII component K02779 ptsG; glucose PTS system EIICB or EIICBA component [EC:2.7.1.199] D spr0668 ptsG; PTS glucose-specific enzyme IIABC component K20108 malT; maltose PTS system EIICB or EIICBA component [EC:2.7.1.208] D spr1566 scrA; Phosphotransferase system enzyme II K02810 scrA; sucrose PTS system EIIBCA or EIIBC component [EC:2.7.1.211] D spr0505 PTS-EII; Phosphotransferase system sugar-specific EII component K02757 bglF; beta-glucoside PTS system EIICBA component [EC:2.7.1.-] D spr1699 treP; Phosphotransferase system, trehalose-specific IIBC component K02819 treB; trehalose PTS system EIIBC or EIIBCA component [EC:2.7.1.201] D spr0780 fruA; Fructose specific-phosphotransferase system IIBC component K02770 fruA; fructose PTS system EIIBC or EIIC component [EC:2.7.1.202] D spr0358 mtlF; Mannitol-specific enzyme IIA component K02798 cmtB; mannitol PTS system EIIA component [EC:2.7.1.197] D spr0356 mtlA; Mannitol PTS EII K02800 mtlA; mannitol PTS system EIICBA or EIICB component [EC:2.7.1.197] D spr0423 PTS-EII; Phosphotransferase system sugar-specific EII component K02786 lacF; lactose PTS system EIIA component [EC:2.7.1.207] D spr1071 lacF; PTS system, lactose-specific IIA component K02786 lacF; lactose PTS system EIIA component [EC:2.7.1.207] D spr0425 PTS-EII; Phosphotransferase system sugar-specific EII component K02788 lacE; lactose PTS system EIICB component [EC:2.7.1.207] D spr1070 lacE; PTS system, lactose-specific IIBC component K02788 lacE; lactose PTS system EIICB component [EC:2.7.1.207] D spr0229 PTS-EIIA; Phosphotransferase system sugar-specific EIIA component K02759 celC; cellobiose PTS system EIIA component [EC:2.7.1.196 2.7.1.205] D spr0280 PTS-EII; Phosphotransferase system sugar-specific EII component K02759 celC; cellobiose PTS system EIIA component [EC:2.7.1.196 2.7.1.205] D spr1836 ptcA; Phosphotransferase system system, cellobiose-specific IIA component K02759 celC; cellobiose PTS system EIIA component [EC:2.7.1.196 2.7.1.205] D spr0230 PTS-EIIB; Phosphotransferase system sugar-specific EIIB component K02760 celA; cellobiose PTS system EIIB component [EC:2.7.1.196 2.7.1.205] D spr0278 PTS-EII; Phosphotransferase system sugar-specific EII component K02760 celA; cellobiose PTS system EIIB component [EC:2.7.1.196 2.7.1.205] D spr1835 ptcB; Phosphotransferase system system, cellobiose-specific IIB component K02760 celA; cellobiose PTS system EIIB component [EC:2.7.1.196 2.7.1.205] D spr1834 ptcC; Phosphotransferase system system, cellobiose-specific IIC component K02761 celB; cellobiose PTS system EIIC component D spr0231 PTS-EIIC; Phosphotransferase system sugar-specific EIIC component K02761 celB; cellobiose PTS system EIIC component D spr0282 PTS-EII; Phosphotransferase system sugar-specific EII component K02761 celB; cellobiose PTS system EIIC component D spr0421 PTS-EII; Phosphotransferase system sugar-specific EII component K02761 celB; cellobiose PTS system EIIC component D spr0562 PTS-EII; Phosphotransferase system sugar-specific EII component K20112 gatA; galactose PTS system EIIA component [EC:2.7.1.204] D spr1081 Hypothetical protein K20112 gatA; galactose PTS system EIIA component [EC:2.7.1.204] D spr0563 Hypothetical protein K20113 gatB; galactose PTS system EIIB component [EC:2.7.1.204] D spr1080 Hypothetical protein K20113 gatB; galactose PTS system EIIB component [EC:2.7.1.204] D spr0564 PTS-EII; Phosphotransferase system sugar-specific EII component K20114 gatC; galactose PTS system EIIC component D spr0261 manL; Phosphotransferase system, mannose-specific EIIAB K02794 manX; mannose PTS system EIIAB component [EC:2.7.1.191] D spr0063 PTS-EII; Phosphotransferase system sugar-specific EII component K02793 manXa; mannose PTS system EIIA component [EC:2.7.1.191] D spr1970 PTS-EII; Phosphotransferase system sugar-specific EII component K02793 manXa; mannose PTS system EIIA component [EC:2.7.1.191] D spr0061 PTS-EIIC; Phosphotransferase system sugar-specific EIIC component K02795 manY; mannose PTS system EIIC component D spr0260 manM; Phosphotransferase system, mannose-specific EIIC K02795 manY; mannose PTS system EIIC component D spr1968 PTS-EII; Phosphotransferase system sugar-specific EII component K02795 manY; mannose PTS system EIIC component D spr0062 PTS-EIID; Phosphotransferase system sugar-specific EIID component K02796 manZ; mannose PTS system EIID component D spr0259 manN; Phosphotransferase system, mannose-specific EIID K02796 manZ; mannose PTS system EIID component D spr1967 PTS-EII; Phosphotransferase system sugar-specific EII component K02796 manZ; mannose PTS system EIID component D spr0291 PTS-EII; Phosphotransferase system sugar-specific EII component K02744 agaF; N-acetylgalactosamine PTS system EIIA component [EC:2.7.1.-] D spr0293 PTS-EII; Phosphotransferase system sugar-specific EII component K02745 agaV; N-acetylgalactosamine PTS system EIIB component [EC:2.7.1.-] D spr0294 PTS-EII; Phosphotransferase system sugar-specific EII component K02746 agaW; N-acetylgalactosamine PTS system EIIC component D spr0295 PTS-EII; Phosphotransferase system sugar-specific EII component K02747 agaE; N-acetylgalactosamine PTS system EIID component D spr1847 PTS-EII; Phosphotransferase system sugar-specific EII component K02821 ulaC; ascorbate PTS system EIIA or EIIAB component [EC:2.7.1.194] D spr1848 PTS-EII; Phosphotransferase system sugar-specific EII component K02822 ulaB; ascorbate PTS system EIIB component [EC:2.7.1.194] D spr1939 Hypothetical protein K02822 ulaB; ascorbate PTS system EIIB component [EC:2.7.1.194] D spr1849 PTS-EII; Phosphotransferase system sugar-specific EII component K03475 ulaA; ascorbate PTS system EIIC component D spr1938 Conserved hypothetical protein K03475 ulaA; ascorbate PTS system EIIC component D spr1604 aqpZ; Aquaporin Z - water channel protein K06188 aqpZ; aquaporin Z D spr1344 glpF; Glycerol uptake facilitator protein paralog K02440 glpF; glycerol uptake facilitator D spr1988 glpF; Glycerol uptake facilitator protein K02440 glpF; glycerol uptake facilitator D spr0915 mscL; Large conductance mechano-sensitive ion channel K03282 mscL; large conductance mechanosensitive channel D spr1597 Hypothetical protein K22044 ybiO; moderate conductance mechanosensitive channel D spr0170 corA; Magnesium and cobalt transporter K03284 corA; magnesium transporter D spr1173 crcB; CrcB protein K06199 crcB; fluoride exporter D spr1172 crcB; CrcB protein K06199 crcB; fluoride exporter D spr1778 hlyX; Hemolysin K03699 tlyC; magnesium and cobalt exporter, CNNM family D spr1672 czcD; Cation diffusion facilitator transporter - heavy metal transport K16264 czcD; cobalt-zinc-cadmium efflux system protein D spr1598 dctA; Dicarboxylate/amino acid:cation (Na+ or H+) symporter K07862 sstT; serine/threonine transporter D spr0573 nha2; Na+/H+ antiporter K24163 nhaK; monovalent cation/hydrogen antiporter D spr0070 trkH; Trk transporter membrane-spanning protein - K+ transport K03498 trkH; trk/ktr system potassium uptake protein D spr0426 trkH; Trk transporter membrane-spanning protein - K+ transport K03498 trkH; trk/ktr system potassium uptake protein D spr0071 trkA; Trk transporter NAD+ binding protein - K+ transport K03499 trkA; trk/ktr system potassium uptake protein D spr0427 trkA; Trk transporter NAD+ binding protein - K+ transport K03499 trkA; trk/ktr system potassium uptake protein D spr1165 pyrP; Uracil permease K02824 uraA; uracil permease D spr1663 pbuX; Nucleobase:cation symporter for xanthine K16169 pbuX; xanthine permease D spr0264 Conserved hypothetical protein K06901 pbuG; adenine/guanine/hypoxanthine permease D spr1045 Conserved hypothetical protein K03281 clcA; chloride channel protein, CIC family D spr0439 Conserved hypothetical protein K03324 yjbB; phosphate:Na+ symporter D spr0145 Hypothetical protein K26605 azlC; branched chain amino acid efflux pump D spr0433 Conserved hypothetical protein K23675 fmnP; riboflavin transporter D spr1113 Hypothetical protein K16788 niaX; niacin transporter D spr0814 Conserved hypothetical protein K22736 VIT; vacuolar iron transporter family protein D spr0973 ftsW; Cell division protein FtsW K03588 ftsW; cell division protein FtsW D spr1178 Hypothetical protein K07243 FTR; high-affinity iron transporter D spr1179 Conserved hypothetical protein K16301 efeB; deferrochelatase/peroxidase EfeB [EC:1.11.1.-] D spr0277 Conserved hypothetical protein K15383 K15383; MtN3 and saliva related transmembrane protein D spr0903 ccdA; Cytochrome c-type biogenesis protein K06196 ccdA; cytochrome c-type biogenesis protein D spr0575 ccdA; Cytochrome c-type biogenesis protein K06196 ccdA; cytochrome c-type biogenesis protein D spr0108 Conserved hypothetical protein K20345 blpB; membrane fusion protein, peptide pheromone/bacteriocin exporter D spr0693 Conserved hypothetical protein K24950 yknX; membrane fusion protein, antimicrobial resistance system D spr1674 Conserved hypothetical protein K03811 pnuC; nicotinamide mononucleotide transporter D spr1641 mgtC; Mg(2+) transport ATPase/permease K07507 mgtC; putative Mg2+ transporter-C (MgtC) family protein C 02044 Secretion system [BR:spr02044] D spr1507 Conserved hypothetical protein K02221 yggT; YggT family protein D spr0856 celA; Competence protein K02237 comEA; competence protein ComEA D spr0654 comEB; dCMP deaminase K01493 comEB; dCMP deaminase [EC:3.5.4.12] D spr0857 celB; Competence protein K02238 comEC; competence protein ComEC D spr2013 comFA; Involved in transformation; required for DNA uptake but not for binding; Related to ATP-dependent RNA/DNA helicases K02240 comFA; competence protein ComFA D spr2012 comFC; Involved in transformation (competence for DNA uptake) K02242 comFC; competence protein ComFC D spr1864 cglA; Competence protein K02243 comGA; competence protein ComGA D spr1863 cglB; Competence protein K02244 comGB; competence protein ComGB D spr1862 cglC; Competence protein K02245 comGC; competence protein ComGC D spr1861 cglD; Competence protein K02246 comGD; competence protein ComGD D spr1859 Conserved hypothetical protein K02248 comGF; competence protein ComGF D spr1628 pilD; Type 4 prepilin peptidase K02236 comC; leader peptidase (prepilin peptidase) / N-methyltransferase [EC:3.4.23.43 2.1.1.-] D spr1544 secA; Preprotein translocase secA subunit K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8] D spr1821 secE; Preprotein translocase secE component K03073 secE; preprotein translocase subunit SecE D spr0877 secG; Protein-export membrane protein secG K03075 secG; preprotein translocase subunit SecG D spr0209 secY; Multispanning membrane protein, translocator of proteins K03076 secY; preprotein translocase subunit SecY D spr1166 ffh; Signal recognition particle (Fifty four homolog) K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4] D spr1123 ftsY; Cell division protein FtsY K03110 ftsY; fused signal recognition particle receptor D spr1840 Conserved hypothetical protein K03210 yajC; preprotein translocase subunit YajC D spr0296 Conserved hypothetical protein K03210 yajC; preprotein translocase subunit YajC D spr1852 Conserved hypothetical protein K03217 yidC; YidC/Oxa1 family membrane protein insertase D spr1790 Conserved hypothetical protein K03217 yidC; YidC/Oxa1 family membrane protein insertase C 02042 Bacterial toxins [BR:spr02042] D spr0371 shetA; Exfoliative toxin A K11041 eta; exfoliative toxin A/B D spr1739 ply; Pneumolysin (sulfhydryl-activated toxin that lyses cholesterol containing membranes) K11031 slo; thiol-activated cytolysin D spr1778 hlyX; Hemolysin K03699 tlyC; magnesium and cobalt exporter, CNNM family D spr1320 Conserved hypothetical protein K11068 hlyIII; hemolysin III C 02022 Two-component system [BR:spr02022] D spr1894 phoR_pnpS; Histidine kinase K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3] D spr1893 phoP_pnpR; Response regulator K07658 phoB1; two-component system, OmpR family, alkaline phosphatase synthesis response regulator PhoP D spr1106 hk02; Histidine kinase K07652 vicK; two-component system, OmpR family, sensor histidine kinase VicK [EC:2.7.13.3] D spr1107 rr02; Response regulator K07668 vicR; two-component system, OmpR family, response regulator VicR D spr0077 hk08; Histidine kinase K10681 saeS; two-component system, OmpR family, sensor histidine kinase SaeS [EC:2.7.13.3] D spr0076 rr08; Response regulator K10682 saeR; two-component system, OmpR family, response regulator SaeR D spr1473 hk01; Histidine kinase K19081 braS; two-component system, OmpR family, sensor histidine kinase BraS/BceS [EC:2.7.13.3] D spr1474 rr01; Response regulator K19082 braR; two-component system, OmpR family, response regulator protein BraR/BceR D spr0708 ciaH; Sensor protein CiaH histide kinase K14982 ciaH; two-component system, OmpR family, sensor histidine kinase CiaH [EC:2.7.13.3] D spr0707 ciaR; Response regulator, transcriptional regulatory protein K14983 ciaR; two-component system, OmpR family, response regulator CiaR D spr1815 hk11; Histidine kinase K07778 desK; two-component system, NarL family, sensor histidine kinase DesK [EC:2.7.13.3] D spr1814 rr11; Response regulator K07693 desR; two-component system, NarL family, response regulator DesR D spr0343 hk03; Histidine kinase K11617 liaS; two-component system, NarL family, sensor histidine kinase LiaS [EC:2.7.13.3] D spr0344 rr03; Response regulator K11618 liaR; two-component system, NarL family, response regulator LiaR D spr0464 hk13; Histidine kinase K07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3] D spr0463 rr13; Response regulator K07707 agrA; two-component system, LytTR family, response regulator AgrA D spr2042 comD; Histidine protein kinase K12294 comD; two-component system, LytTR family, sensor histidine kinase ComD [EC:2.7.13.3] D spr2041 comE; Response regulator K12295 comE; two-component system, LytTR family, response regulator ComE D spr0579 hk09; Histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3] D spr0153 hk07; Histidine kinase K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3] D spr0154 rr07; Response regulator K07720 yesN; two-component system, response regulator YesN C 02035 Bacterial motility proteins [BR:spr02035] D spr0146 ABC-SBP; ABC transporter substrate-binding protein - amino acid transport K02424 tcyA; L-cystine transport system substrate-binding protein C 03037 Cilium and associated proteins C 04812 Cytoskeleton proteins [BR:spr04812] D spr1510 ftsZ; Cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ D spr1511 ftsA; Cell division protein FtsA K03590 ftsA; cell division protein FtsA D spr2046 spo0J; Chromosome segregation protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein C 04147 Exosome [BR:spr04147] D spr1036 eno; Enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D spr1825 gapA; Glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] D spr0441 pgk; Phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3] D spr0797 pykF; Pyruvate kinase I; fructose-stimulated K00873 PK; pyruvate kinase [EC:2.7.1.40] D spr0679 ppiA; Peptidyl-prolyl cis-trans isomerase K03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8] D spr1722 groEL; Chaperonin GroEL K04077 groEL; chaperonin GroEL [EC:5.6.1.7] D spr0455 dnaK; Class I heat-shock protein (molecular chaperone) K04043 dnaK; molecular chaperone DnaK D spr1882 gpi; Glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9] D spr2033 imdH; Inosine-5'-monophosphate dehydrogenase K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205] D spr1343 tufA; Translation elongation factor TU K02358 tuf; elongation factor Tu D spr0458 Conserved hypothetical protein K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-] D spr1100 ldh; L-lactate dehydrogenase K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27] D spr0966 Conserved hypothetical protein K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D spr0210 adk; Adenylate kinase (ATP-AMP transphosphorylase) K00939 adk; adenylate kinase [EC:2.7.4.3] D spr1435 apt; Adenine phosphoribosyltransferase K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7] D spr0103 argH; Arginine succinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1] D spr0102 argG; Argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5] D spr1954 Hypothetical protein K01206 FUCA; alpha-L-fucosidase [EC:3.2.1.51] D spr1668 galK; Galactokinase K00849 galK; galactokinase [EC:2.7.1.6] D spr1029 glgB; 1,4-alpha-glucan branching enzyme K00700 GBE1; 1,4-alpha-glucan branching enzyme [EC:2.4.1.18] D spr1991 glpK; Glycerol kinase K00864 glpK; glycerol kinase [EC:2.7.1.30] D spr0444 glnA; Glutamine synthetase type 1 K01915 glnA; glutamine synthetase [EC:6.3.1.2] D spr0051 purH; Phosphoribosylaminoimidazolecarboxamide formyltransferase K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10] D spr1048 acoL; Dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D spr1122 zwf; Glucose-6-phosphate 1-dehydrogenase K00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363] D spr1432 tpi; Triose phosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] D spr1499 gpmA; Phosphoglyceromutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] C 02048 Prokaryotic defense system [BR:spr02048] D spr0792 hsdR; Type 1 restriction modification system endonuclease R K01153 hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3] D spr0450 hsdR; EcoA type I restriction-modification enzyme R subunit K01153 hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3] D spr0448 hsdS; Type I site-specific deoxyribonuclease chain S K01154 hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3] D spr0446 hsdS; Type I restriction enzyme EcoKI specificity protein (S protein) K01154 hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3] D spr0445 hsdS; type I restriction enzyme K01154 hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3] D spr0449 hsdM; EcoE type I restriction modification enzyme M subunit K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72] D spr0790 hsdM; Type I restriction modification enzyme methylase subunit K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72] D spr1665 dpnC; Type II restriction enzyme DpnI (dpnC) K01155 E3.1.21.4; type II restriction enzyme [EC:3.1.21.4] D spr1855 Conserved hypothetical protein K00571 E2.1.1.72; site-specific DNA-methyltransferase (adenine-specific) [EC:2.1.1.72] D spr1287 spnIM; DNA modification methyltransferase K00571 E2.1.1.72; site-specific DNA-methyltransferase (adenine-specific) [EC:2.1.1.72] D spr1103 Hypothetical protein K06218 relE; mRNA interferase RelE/StbE D spr0253 Conserved hypothetical protein K19157 yafQ; mRNA interferase YafQ [EC:3.1.-.-] D spr0252 Hypothetical protein K07473 dinJ; DNA-damage-inducible protein J D spr1585 Conserved hypothetical protein K19158 yoeB; toxin YoeB [EC:3.1.-.-] D spr1586 Conserved hypothetical protein K19159 yefM; antitoxin YefM D spr0952 Conserved hypothetical protein K16214 pezT; UDP-N-acetylglucosamine kinase [EC:2.7.1.176] D spr0951 Hypothetical protein K18830 pezA; HTH-type transcriptional regulator / antitoxin PezA D spr1510 ftsZ; Cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ D spr0757 parC; Topoisomerase IV subunit A K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2] D spr0756 parE; Topoisomerase IV subunit B K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2] D spr0783 Probable pyridoxal-phosphate dependent aminotransferase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] D spr1001 nifS; Pyridoxal-phosphate dependent aminotransferase K04487 iscS; cysteine desulfurase [EC:2.8.1.7] C 04030 G protein-coupled receptors C 04050 Cytokine receptors C 04054 Pattern recognition receptors C 03310 Nuclear receptors C 04040 Ion channels [BR:spr04040] C 04031 GTP-binding proteins C 04052 Cytokines and neuropeptides C 04515 Cell adhesion molecules C 04090 CD molecules [BR:spr04090] C 01504 Antimicrobial resistance genes [BR:spr01504] D spr0554 Conserved hypothetical protein K07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14] D spr1982 dltA; D-alanine-D-alanyl carrier protein ligase K03367 dltA; D-alanine--poly(phosphoribitol) ligase subunit 1 [EC:6.1.1.13] D spr1981 dltB; D-alanine transfer from Dcp to undecaprenol-phosphate K03739 dltB; membrane protein involved in D-alanine export D spr1980 dltC; D-alanyl carrier protein K14188 dltC; D-alanine--poly(phosphoribitol) ligase subunit 2 [EC:6.1.1.13] D spr1979 dltD; D-alanine transfer from undecaprenol-phosphate to the poly(glycerophosphate) chain K03740 dltD; D-alanine transfer protein C 00535 Proteoglycans C 00536 Glycosaminoglycan binding proteins C 00537 Glycosylphosphatidylinositol (GPI)-anchored proteins C 04091 Lectins C 04990 Domain-containing proteins not elsewhere classified B B 09185 Viral protein families C 03200 Viral proteins C 03210 Viral fusion proteins B B 09184 RNA family C 03100 Non-coding RNAs [BR:spr03100] D sprt02 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D sprt54 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D sprt41 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D sprt29 tRNA-Ala K14218 tRNA-Ala; tRNA Ala D sprt08 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D sprt58 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D sprt09 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D sprt21 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D sprt33 tRNA-Arg K14219 tRNA-Arg; tRNA Arg D sprt03 tRNA-Asn K14220 tRNA-Asn; tRNA Asn D sprt56 tRNA-Asn K14220 tRNA-Asn; tRNA Asn D sprt27 tRNA-Asp K14221 tRNA-Asp; tRNA Asp D sprt39 tRNA-Asp K14221 tRNA-Asp; tRNA Asp D sprt31 tRNA-Cys K14222 tRNA-Cys; tRNA Cys D sprt05 tRNA-Gln K14223 tRNA-Gln; tRNA Gln D sprt44 tRNA-Gln K14223 tRNA-Gln; tRNA Gln D sprt01 tRNA-Glu K14224 tRNA-Glu; tRNA Glu D sprt57 tRNA-Glu K14224 tRNA-Glu; tRNA Glu D sprt42 tRNA-Glu K14224 tRNA-Glu; tRNA Glu D sprt55 tRNA-Glu K14224 tRNA-Glu; tRNA Glu D sprt30 tRNA-Glu K14224 tRNA-Glu; tRNA Glu D sprt14 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D sprt52 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D sprt23 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D sprt35 tRNA-Gly K14225 tRNA-Gly; tRNA Gly D sprt45 tRNA-His K14226 tRNA-His; tRNA His D sprt13 tRNA-Ile K14227 tRNA-Ile; tRNA Ile D sprt51 tRNA-Ile K14227 tRNA-Ile; tRNA Ile D sprt22 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D sprt34 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D sprt43 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D sprt25 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D sprt37 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D sprt10 tRNA-Leu K14228 tRNA-Leu; tRNA Leu D sprt26 tRNA-Lys K14229 tRNA-Lys; tRNA Lys D sprt38 tRNA-Lys K14229 tRNA-Lys; tRNA Lys D sprt11 tRNA-Lys K14229 tRNA-Lys; tRNA Lys D sprt19 tRNA-Met K14230 tRNA-Met; tRNA Met D sprt18 tRNA-Met K14230 tRNA-Met; tRNA Met D sprt16 tRNA-Met K14230 tRNA-Met; tRNA Met D sprt49 tRNA-Met K14230 tRNA-Met; tRNA Met D sprt15 tRNA-Phe K14231 tRNA-Phe; tRNA Phe D sprt48 tRNA-Phe K14231 tRNA-Phe; tRNA Phe D sprt20 tRNA-Pro K14232 tRNA-Pro; tRNA Pro D sprt32 tRNA-Pro K14232 tRNA-Pro; tRNA Pro D sprt17 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D sprt50 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D sprt12 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D sprt06 tRNA-Ser K14233 tRNA-Ser; tRNA Ser D sprt07 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D sprt24 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D sprt36 tRNA-Thr K14234 tRNA-Thr; tRNA Thr D sprt46 tRNA-Trp K14235 tRNA-Trp; tRNA Trp D sprt47 tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr D sprt04 tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr D sprt28 tRNA-Val K14237 tRNA-Val; tRNA Val D sprt40 tRNA-Val K14237 tRNA-Val; tRNA Val D sprt53 tRNA-Val K14237 tRNA-Val; tRNA Val D sprr01 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D sprr06 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D sprr09 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D sprr12 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA D sprr02 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D sprr05 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D sprr08 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D sprr11 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA D sprr03 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D sprr04 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D sprr07 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D sprr10 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA D sprs01 scRNA; scRNA K01983 ffs; SRP RNA D sprs02 rnpB; Ribonuclease P - RNA component K01978 rnpB; M1 RNA D sprs03 ssrA; ssrA K15035 ssrA; transfer-messenger RNA # A09190 Not Included in Pathway or Brite B B 09191 Unclassified: metabolism C 99980 Enzymes with EC numbers D spr0290 gno; 5-keto-D-gluconate 5-reductase K00046 idnO; gluconate 5-dehydrogenase [EC:1.1.1.69] D spr0627 lctO; Lactate oxidase K10530 lctO; L-lactate oxidase [EC:1.1.3.2] D spr1217 msrA; Peptide methionine sulfoxide reductase K12267 msrAB; peptide methionine sulfoxide reductase msrA/msrB [EC:1.8.4.11 1.8.4.12] D spr0577 msrA; Peptide methionine sulfoxide reductase paralog K12267 msrAB; peptide methionine sulfoxide reductase msrA/msrB [EC:1.8.4.11 1.8.4.12] D spr1409 Conserved hypothetical protein K11209 yghU; GSH-dependent disulfide-bond oxidoreductase [EC:1.8.4.-] D spr1495 tpx; Thioredoxin-linked thiol peroxidase K11065 tpx; thioredoxin-dependent peroxiredoxin [EC:1.11.1.24] D spr1421 trxB; Thioredoxin reductase K21567 fnr; ferredoxin/flavodoxin---NADP+ reductase [EC:1.18.1.2 1.19.1.1] D spr0185 nrdG; NrdD activating enzyme, generating glycyl radical K04068 nrdG; anaerobic ribonucleoside-triphosphate reductase activating protein [EC:1.97.1.4] D spr0226 pflE; Pyruvate formate-lyase 3 K04069 pflA; pyruvate formate lyase activating enzyme [EC:1.97.1.4] D spr1791 pflC; Pyruvate-formate lyase activating enzyme K04069 pflA; pyruvate formate lyase activating enzyme [EC:1.97.1.4] D spr0880 tehB; Tellurite resistance K16868 tehB; tellurite methyltransferase [EC:2.1.1.265] D spr0333 Conserved hypothetical protein K07444 ypsC; putative N6-adenine-specific DNA methylase [EC:2.1.1.-] D spr0508 Conserved hypothetical protein K22441 paiA; diamine N-acetyltransferase [EC:2.3.1.57] D spr1269 lgt; Prolipoprotein diacylglycerol transferase K13292 lgt; phosphatidylglycerol---prolipoprotein diacylglyceryl transferase [EC:2.5.1.145] D spr1324 apbE; Thiamine biosynthesis lipoprotein K03734 apbE; FAD:protein FMN transferase [EC:2.7.1.180] D spr0400 Conserved hypothetical protein K07030 fakA; fatty acid kinase [EC:2.7.2.18] D spr1419 Conserved hypothetical protein K18672 dacA; diadenylate cyclase [EC:2.7.7.85] D spr1270 hprK; HPr(ser-P)kinase/phosphatase K06023 hprK; HPr kinase/phosphorylase [EC:2.7.11.- 2.7.4.-] D spr0539 estA; tributyrin esterase K03930 estA; putative tributyrin esterase [EC:3.1.1.-] D spr1595 Conserved hypothetical protein K07015 yqeG; putative phosphatase [EC:3.1.3.-] D spr2010 Conserved hypothetical protein K22927 gdpP; cyclic-di-AMP phosphodiesterase [EC:3.1.4.59] D spr1805 Conserved hypothetical protein K03424 tatD; TatD DNase family protein [EC:3.1.21.-] D spr1804 Conserved hypothetical protein K05985 rnmV; ribonuclease M5 [EC:3.1.26.8] D spr0310 dexB; Alpha, 1-6-glucosidase K01215 dexB; glucan 1,6-alpha-glucosidase [EC:3.2.1.70] D spr0328 Conserved hypothetical protein K17624 engCP; endo-alpha-N-acetylgalactosaminidase [EC:3.2.1.97] D spr0292 ugl; Unsaturated glucuronyl hydrolase K18581 ugl; unsaturated chondroitin disaccharide hydrolase [EC:3.2.1.180] D spr1754 lytA; Autolysin (N-acetylmuramoyl-L-alanine amidase) K01447 xlyAB; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] D spr1310 fms; Peptide deformylase, N-formylmethionylaminoacyl-tRNA deformylase K01462 PDF; peptide deformylase [EC:3.5.1.88] D spr1408 def; Formylmethionine deformylase K01462 PDF; peptide deformylase [EC:3.5.1.88] D spr1333 pgdA; Peptidoglycan GlcNAc deacetylase K22278 pgdA; peptidoglycan-N-acetylglucosamine deacetylase [EC:3.5.1.104] D spr1425 aldR; Transcription regulator K09022 ridA; 2-iminobutanoate/2-iminopropanoate deaminase [EC:3.5.99.10] D spr1205 Conserved hypothetical protein K24914 lanKC; class III lanthionine synthetase [EC:3.13.2.4] D spr1767 cylM; CylM protein, cytolytic toxin system K27862 lanM; class II lanthipeptide synthase [EC:3.13.2.4] D spr0730 Conserved hypothetical protein K17758 nnrD; ADP-dependent NAD(P)H-hydrate dehydratase [EC:4.2.1.136] D spr0286 hysA; Hyaluronate lyase precursor (hyaluronidase/hyase) K01727 hysA; hyaluronate lyase [EC:4.2.2.1] D spr1971 fucU; Fucose pathway protein, function unknown K02431 fucU; L-fucose mutarotase [EC:5.1.3.29] D spr1410 pacL; P-type ATPase - calcium transporter K01537 ATP2C; P-type Ca2+ transporter type 2C [EC:7.2.2.10] D spr1464 ctpE; P-type ATPase - metal cation transport K12952 ctpE; cation-transporting P-type ATPase E [EC:7.2.2.-] C 99981 Carbohydrate metabolism D spr0664 Conserved hypothetical protein K04767 acuB; acetoin utilization protein AcuB C 99982 Energy metabolism D spr1458 fer; Ferredoxin K05337 fer; ferredoxin D spr0774 nifU; NifU protein K04488 iscU; nitrogen fixation protein NifU and related proteins C 99983 Lipid metabolism D spr1415 Conserved hypothetical protein K25232 fakB; fatty acid kinase fatty acid binding subunit D spr1019 Conserved hypothetical protein K25232 fakB; fatty acid kinase fatty acid binding subunit C 99984 Nucleotide metabolism D spr0156 Conserved hypothetical protein K03647 nrdI; protein involved in ribonucleotide reduction D spr1779 endA; DNA-entry nuclease (competence-specific nuclease) K15051 endA; DNA-entry nuclease C 99985 Amino acid metabolism D spr1509 Conserved hypothetical protein K06997 yggS; PLP dependent protein C 99986 Glycan metabolism C 99987 Cofactor metabolism C 99988 Secondary metabolism C 99999 Others B B 09192 Unclassified: genetic information processing C 99973 Transcription D spr1262 Conserved hypothetical protein K16509 spxA; regulatory protein spx D spr0808 tex; Toxin expression - transcriptional accessory protein K06959 tex; protein Tex C 99974 Translation D spr1392 Conserved hypothetical protein K07570 GSP13; general stress protein 13 C 99975 Protein processing D spr0362 ropA; Trigger factor K03545 tig; trigger factor D spr0879 smpB; Small protein B K03664 smpB; SsrA-binding protein D spr1064 nrdH; Glutaredoxin-like protein involved in electron transport system for ribonucleotide reductase system NrdEF K06191 nrdH; glutaredoxin-like protein NrdH D spr1220 mecA; Negative regulator of genetic competence K16511 mecA1_2; adapter protein MecA 1/2 C 99976 Replication and repair D spr0996 radC; DNA repair protein K03630 radC; DNA repair protein RadC D spr1795 Conserved hypothetical protein K09760 rmuC; DNA recombination protein RmuC D spr1390 Conserved hypothetical protein K07461 K07461; putative endonuclease D spr1144 smf; DNA processing Smf protein K04096 smf; DNA processing protein D spr1433 Conserved hypothetical protein K02086 dnaD; DNA replication protein D spr1616 cshA; Chromosome segregation helicase K07478 ycaJ; putative ATPase D spr1367 IS1239; Transposase K07482 K07482; transposase, IS30 family D spr1298 Degenerate transposase K07484 K07484; transposase D spr1721 Degenerate transposase (fusion of orf1 and orf2) K07485 K07485; transposase D spr0818 Degenerate transposase K07486 K07486; transposase D spr0718 Transposase K07494 K07494; putative transposase D spr0644 Degenerate transposase K07494 K07494; putative transposase D spr1338 Degenerate transposase K07494 K07494; putative transposase C 99979 Viral proteins C 99998 Others D spr1010 Conserved hypothetical protein K09747 ebfC; nucleoid-associated protein EbfC B B 09193 Unclassified: signaling and cellular processes C 99977 Transport D spr0905 yfnA; Cationic amino acid transporter - APC Superfamily K03294 TC.APA; basic amino acid/polyamine antiporter, APA family D spr0648 Sodium-dependent transporter K03308 TC.NSS; neurotransmitter:Na+ symporter, NSS family D spr0369 dagA; D-alanine glycine permease K03310 TC.AGCS; alanine or glycine:cation symporter, AGCS family D spr0551 brnQ; Branched-chain amino acid transport system carrier protein K03311 TC.LIVCS; branched-chain amino acid:cation transporter, LIVCS family C 99978 Cell growth D spr0334 Conserved hypothetical protein K20073 mapZ; mid-cell-anchored protein Z D spr1851 Hypothetical protein K06346 jag; spoIIIJ-associated protein D spr0942 ccrB; Low similarity to site-specific recombinase K06400 spoIVCA; site-specific DNA recombinase C 99993 Cell motility C 99995 Signaling proteins D spr0598 typA; GTP-binding protein TypA/BipA (tyrosine phosphorylated protein A) K06207 typA; GTP-binding protein D spr0217 Conserved hypothetical protein K07166 K07166; ACT domain-containing protein D spr0849 phoL; PhoH-like protein K06217 phoH; phosphate starvation-inducible protein PhoH and related proteins C 99992 Structural proteins D spr0890 Hypothetical protein K07273 acm; lysozyme C 99994 Others D spr1252 phoU; Phosphate transport system regulatory protein K02039 phoU; phosphate transport system protein D spr1899 phoU; Negative regulator of pho regulon for phosphate transport K02039 phoU; phosphate transport system protein D spr1649 Conserved hypothetical protein K02039 phoU; phosphate transport system protein D spr1139 cutC; Copper sensitivity K06201 cutC; copper homeostasis protein B B 09194 Poorly characterized C 99996 General function prediction only D spr0881 coiA; Competence protein K06198 coiA; competence protein CoiA D spr1726 Conserved hypothetical protein K06878 K06878; tRNA-binding protein D spr0775 Conserved hypothetical protein K09014 sufB; Fe-S cluster assembly protein SufB D spr0772 Conserved hypothetical protein K09015 sufD; Fe-S cluster assembly protein SufD D spr0574 Conserved hypothetical protein K07058 K07058; membrane protein D spr0084 Conserved hypothetical protein K07146 K07146; UPF0176 protein D spr1163 lemA; Cytoplasmic membrane protein K03744 lemA; LemA protein D spr0809 Conserved hypothetical protein K03095 sprL; SprT-like protein D spr0889 Conserved hypothetical protein K08974 K08974; putative membrane protein D spr0804 Conserved hypothetical protein K08986 ycgQ; putative membrane protein D spr1873 Conserved hypothetical protein K08987 K08987; putative membrane protein D spr1455 phnA; Required for expression of the phosphonate utilization phenotype in E. coli K06193 phnA; protein PhnA C 99997 Function unknown D spr1169 Conserved hypothetical protein K06885 K06885; uncharacterized protein D spr1787 Conserved hypothetical protein K06890 K06890; uncharacterized protein D spr0033 Conserved hypothetical protein K06929 K06929; uncharacterized protein D spr0683 Conserved hypothetical protein K06960 K06960; uncharacterized protein D spr0805 Conserved hypothetical protein K07089 K07089; uncharacterized protein D spr1694 Conserved hypothetical protein K07095 K07095; uncharacterized protein D spr1114 Conserved hypothetical protein K07105 K07105; uncharacterized protein D spr1468 Conserved hypothetical protein K07118 K07118; uncharacterized protein D spr0592 Conserved hypothetical protein K07124 K07124; uncharacterized protein D spr0569 Hypothetical protein K07139 K07139; uncharacterized protein D spr1688 Conserved hypothetical protein K08998 K08998; uncharacterized protein D spr0486 Conserved hypothetical protein K09155 K09155; uncharacterized protein D spr0218 Conserved hypothetical protein K09157 K09157; uncharacterized protein D spr1952 Conserved hypothetical protein K09704 K09704; uncharacterized protein D spr1892 Conserved hypothetical protein K09705 K09705; uncharacterized protein D spr1167 Conserved hypothetical protein K09787 K09787; uncharacterized protein D spr1140 Conserved hypothetical protein K09790 K09790; uncharacterized protein D spr0847 Conserved hypothetical protein K00243 K00243; uncharacterized protein D spr1405 Conserved hypothetical protein K09861 K09861; uncharacterized protein D spr0239 Hypothetical protein K09962 K09962; uncharacterized protein D spr1697 Hypothetical protein K09976 K09976; uncharacterized protein D spr1013 Conserved hypothetical protein K07584 ysxB; uncharacterized protein D spr1719 Conserved hypothetical protein K07586 ygaC; uncharacterized protein D spr0479 Conserved hypothetical protein K07742 ylxR; uncharacterized protein ! #
#[ KO | BRITE | KEGG2 | KEGG ]
#Last updated: October 29, 2024