+D	AMR gene	KO
#<h2><a href="/kegg/brite.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; Antimicrobial Resistance Genes - Serratia sp. AS12</h2>
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A<b>Gene variants</b>
B  beta-Lactamase genes
C    Class A [MT]
C    Class D [MT]
C    Class C [MT]
C    Class B [MT]
B  Aminoglycoside resistance genes
C    N-Acetyltransferases
C    Other acetyltransferases
C    O-Nucleotidyltransferases
C    O-Phosphotransferases
D      SerAS12_2171 aminoglycoside/hydroxyurea antibiotic resistance kinase	K04343 strB; streptomycin 6-kinase [EC:2.7.1.72] 
C    16S rRNA methyltransferases
B  Tetracycline resistance genes
C    Transporters
C    Others
B  Macrolide resistance genes
C    23S rRNA methyltransferases
C    Transporters
D      SerAS12_0052 major facilitator superfamily MFS_1	K08160 mdfA; MFS transporter, DHA1 family, multidrug/chloramphenicol efflux transport protein 
C    Others
B  Phenicol resistance genes
C    Transporters
C    Acetyltransferases
D      SerAS12_3544 Chloramphenicol O-acetyltransferase	K00638 catB; chloramphenicol O-acetyltransferase type B [EC:2.3.1.28] 
C    Phosphotransferase
C    23S rRNA methyltransferase
B  Sulfonamide resistance genes
C    Dihydropteroate synthase
B  Trimethoprim resistance genes
C    Dihydrofolate reductases
B  Quinolone resistance genes
C    Transporter
D      SerAS12_2724 major facilitator superfamily MFS_1	K08167 smvA; MFS transporter, DHA2 family, multidrug resistance protein 
C    Other
D      SerAS12_1995 pentapeptide repeat protein	K18555 qnr; fluoroquinolone resistance protein 
B  Rifamycin resistance genes
C    ADP-ribosyl transferases
C    Oxygenases
B  Fosfomycin resistance genes
C    Transferases
C    Others
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A<b>Gene sets</b>
B  beta-Lactam resistance modules
C    Methicillin resistance [MD:M00625]
C    beta-Lactam resistance, Bla system [MD:M00627]
C    Imipenem resistance, repression of porin OprD [MD:M00745]
B  Vancomycin resistance modules
C    Vancomycin resistance, D-Ala-D-Lac type [MD:M00651]
D      SerAS12_2306 peptidase M15D vanX D-ala-D-ala dipeptidase	K08641 vanX; zinc D-Ala-D-Ala dipeptidase [EC:3.4.13.22] 
C    Vancomycin resistance, D-Ala-D-Ser type [MD:M00652]
D      B  Tetracycline resistance
C    Tetracycline resistance, efflux pump Tet38 [MD:M00704]
B  CAMP resistance modules
C    Cationic antimicrobial peptide (CAMP) resistance, dltABCD operon [MD:M00725]
C    Cationic antimicrobial peptide (CAMP) resistance, lysyl-phosphatidylglycerol (L-PG) synthase MprF [MD:M00726]
C    Cationic antimicrobial peptide (CAMP) resistance, VraFG transporter [MD:M00730]
C    Cationic antimicrobial peptide (CAMP) resistance, protease PgtE [MD:M00744]
D      SerAS12_1966 integral membrane sensor signal transduction histidine kinase	K07637 phoQ; two-component system, OmpR family, sensor histidine kinase PhoQ [EC:2.7.13.3] 
D      SerAS12_1967 two component transcriptional regulator, winged helix family	K07660 phoP; two-component system, OmpR family, response regulator PhoP 
B  Multipdrug resistance modules
C    Multidrug resistance, efflux pump MexAB-OprM [MD:M00718]
D      SerAS12_2459 efflux transporter, RND family, MFP subunit	K03585 acrA; membrane fusion protein, multidrug efflux system 
D      SerAS12_1055 efflux transporter, RND family, MFP subunit	K03585 acrA; membrane fusion protein, multidrug efflux system 
D      SerAS12_1054 transporter, hydrophobe/amphiphile efflux-1 (HAE1) family	K18138 acrB; multidrug efflux pump 
D      SerAS12_2458 transporter, hydrophobe/amphiphile efflux-1 (HAE1) family	K18138 acrB; multidrug efflux pump 
D      SerAS12_2457 RND efflux system, outer membrane lipoprotein, NodT family	K18139 oprM; outer membrane protein, multidrug efflux system 
C    Multidrug resistance, efflux pump MexCD-OprJ [MD:M00639]
C    Multidrug resistance, efflux pump MexEF-OprN [MD:M00641]
C    Multidrug resistance, efflux pump MexJK-OprM [MD:M00642]
D      SerAS12_2457 RND efflux system, outer membrane lipoprotein, NodT family	K18139 oprM; outer membrane protein, multidrug efflux system 
C    Multidrug resistance, efflux pump MexXY-OprM [MD:M00643]
D      SerAS12_2457 RND efflux system, outer membrane lipoprotein, NodT family	K18139 oprM; outer membrane protein, multidrug efflux system 
C    Multidrug resistance, efflux pump MexPQ-OpmE [MD:M00769]
D      SerAS12_1079 transcriptional regulator, MerR family	K19591 cueR; MerR family transcriptional regulator, copper efflux regulator 
C    Multidrug resistance, efflux pump AdeABC [PATH:map01501] [MD:M00649]
D      SerAS12_2417 transporter, hydrophobe/amphiphile efflux-1 (HAE1) family	K18146 adeB; multidrug efflux pump 
C    Multidrug resistance, efflux pump AcrEF-TolC [MD:M00696]
D      SerAS12_4384 type I secretion outer membrane protein, TolC family	K12340 tolC; outer membrane protein 
C    Multidrug resistance, efflux pump MdtEF-TolC [MD:M00697]
D      SerAS12_4384 type I secretion outer membrane protein, TolC family	K12340 tolC; outer membrane protein 
C    Multidrug resistance, efflux pump BpeEF-OprC [MD:M00698]
D      SerAS12_2037 transcriptional regulator, LysR family	K18900 bpeT; LysR family transcriptional regulator, regulator for bpeEF and oprC 
D      SerAS12_4257 transcriptional regulator, LysR family	K18900 bpeT; LysR family transcriptional regulator, regulator for bpeEF and oprC 
C    Multidrug resistance, efflux pump AbcA [MD:M00700]
C    Multidrug resistance, efflux pump NorB [MD:M00702]
C    Multidrug resistance, efflux pump QacA [MD:M00714]
D      SerAS12_2724 major facilitator superfamily MFS_1	K08167 smvA; MFS transporter, DHA2 family, multidrug resistance protein 
C    Multidrug resistance, efflux pump MepA [MD:M00705]
C    Multidrug resistance, repression of porin OmpF [MD:M00746]
D      SerAS12_1701 porin Gram-negative type	K09476 ompF; outer membrane pore protein F 
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#Last updated: December 28, 2017