+E Messenger RNA Biogenesis KO
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Messenger RNA Biogenesis - Thamnophis sirtalis (common garter snake)
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AEukaryotic type
B mRNA processing factors
C 5' end processing
D Capping factors
E 106538120 RNMT; mRNA cap guanine-N7 methyltransferase K00565 RNMT; mRNA (guanine-N7-)-methyltransferase [EC:2.1.1.56]
E 106537437 CDK7; cyclin-dependent kinase 7 K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
E 106539335 CMTR1; cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 K14589 CMTR1; cap1 methyltransferase [EC:2.1.1.57]
E 106541444 CMTR2; cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2 K14590 CMTR2; cap2 methyltransferase [EC:2.1.1.296]
D Cap binding complex
E 106546625 nuclear cap-binding protein subunit 1 isoform X1 K12882 NCBP1; nuclear cap-binding protein subunit 1
E 106546626 nuclear cap-binding protein subunit 1-like K12882 NCBP1; nuclear cap-binding protein subunit 1
C 3' end processing
D Pre-mRNA cleavage factor Im (CFIm)
E 106547926 NUDT21; cleavage and polyadenylation specificity factor subunit 5 K14397 NUDT21; cleavage and polyadenylation specificity factor subunit 5
E 106553823 CPSF6; cleavage and polyadenylation specificity factor subunit 6 isoform X1 K14398 CPSF6_7; cleavage and polyadenylation specificity factor subunit 6/7
D Pre-mRNA cleavage factor IIm (CFIIm)
E 106541472 CLP1; polyribonucleotide 5'-hydroxyl-kinase Clp1 K14399 CLP1; polyribonucleotide 5'-hydroxyl-kinase [EC:2.7.1.78]
E 106547146 PCF11; pre-mRNA cleavage complex 2 protein Pcf11 K14400 PCF11; pre-mRNA cleavage complex 2 protein Pcf11
D Cleavage and polyadenylation specificity factor (CPSF) complex
E 106545221 cleavage and polyadenylation specificity factor subunit 2 K14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2
E 106548142 pre-mRNA 3'-end-processing factor FIP1-like K14405 FIP1L1; pre-mRNA 3'-end-processing factor FIP1
E 106555289 pre-mRNA 3'-end-processing factor FIP1-like isoform X1 K14405 FIP1L1; pre-mRNA 3'-end-processing factor FIP1
E 106540901 WDR33; pre-mRNA 3' end processing protein WDR33 isoform X1 K15542 PFS2; polyadenylation factor subunit 2
E 106542506 WDR82; WD repeat-containing protein 82 K14962 WDR82; COMPASS component SWD2
E 106547126 PPP1CA; serine/threonine-protein phosphatase PP1-alpha catalytic subunit K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E 106548633 serine/threonine-protein phosphatase PP1-gamma catalytic subunit K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E 106538243 PPP1CB; serine/threonine-protein phosphatase PP1-beta catalytic subunit isoform X1 K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
D Cleavage stimulation factor (CSTF) complex
E 106547209 CSTF1; cleavage stimulation factor subunit 1 K14406 CSTF1; cleavage stimulation factor subunit 1
E 106551713 cleavage stimulation factor subunit 2-like K14407 CSTF2; cleavage stimulation factor subunit 2
E 106539779 CSTF3; cleavage stimulation factor subunit 3 K14408 CSTF3; cleavage stimulation factor subunit 3
E 106546608 SYMPK; symplekin K06100 SYMPK; symplekin
D U7-dependent histone pre-mRNA processing factors
E 106555543 SNRPB; small nuclear ribonucleoprotein-associated proteins B and B' K11086 SNRPB; small nuclear ribonucleoprotein B and B'
E 106551285 SNRPD3; small nuclear ribonucleoprotein Sm D3 K11088 SNRPD3; small nuclear ribonucleoprotein D3
E 106557113 SNRPE; small nuclear ribonucleoprotein E K11097 SNRPE; small nuclear ribonucleoprotein E
E 106552109 SNRPF; small nuclear ribonucleoprotein F K11098 SNRPF; small nuclear ribonucleoprotein F
E 106542622 SNRPG; small nuclear ribonucleoprotein G K11099 SNRPG; small nuclear ribonucleoprotein G
E 106549794 LSM10; U7 snRNA-associated Sm-like protein LSm10 K25591 LSM10; U7 snRNA-associated Sm-like protein LSm10
E 106543527 LSM11; U7 snRNA-associated Sm-like protein LSm11 K25592 LSM11; U7 snRNA-associated Sm-like protein LSm11
E 106545221 cleavage and polyadenylation specificity factor subunit 2 K14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2
E 106551713 cleavage stimulation factor subunit 2-like K14407 CSTF2; cleavage stimulation factor subunit 2
E 106546608 SYMPK; symplekin K06100 SYMPK; symplekin
E 106553305 SLBP; histone RNA hairpin-binding protein K18710 SLBP; histone RNA hairpin-binding protein
E 106546323 CASP8AP2; CASP8-associated protein 2 K25593 CASP8AP2; CASP8-associated protein 2
D DRB sensitivity inducing factor (DSIF) complex
E 106539878 SUPT4H1; transcription elongation factor SPT4 K15171 SUPT4H1; transcription elongation factor SPT4
E 106540550 SUPT5H; transcription elongation factor SPT5 K15172 SUPT5H; transcription elongation factor SPT5
D N6-methyltransferase complex
E 106549662 N6-adenosine-methyltransferase subunit METTL14 K23960 METTL14; mRNA m6A methyltransferase non-catalytic subunit
E 106553772 methyltransferase-like protein 4 K24174 METTL4; N(6)-adenine-specific DNA methyltransferase [EC:2.1.1.72]
E 106554152 METTL16; methyltransferase-like protein 16 K11393 METTL16; U6 snRNA m6A methyltransferase [EC:2.1.1.346]
E 106552322 WTAP; pre-mRNA-splicing regulator WTAP K22824 WTAP; pre-mRNA-splicing regulator WTAP
E 106546399 KIAA1429; protein virilizer homolog isoform X1 K22910 VIRMA; protein virilizer
E 106549634 RBM15B; putative RNA-binding protein 15B K13190 RBM15; RNA-binding protein 15
E 106540759 RBM15; putative RNA-binding protein 15 K13190 RBM15; RNA-binding protein 15
E 106554060 ZC3H13; zinc finger CCCH domain-containing protein 13 K22909 ZC3H13; zinc finger CCCH domain-containing protein 13
E 106546141 CBLL1; E3 ubiquitin-protein ligase Hakai K15685 CBLL1; E3 ubiquitin-protein ligase Hakai [EC:2.3.2.27]
D Poly(A) addition factors
E 106540469 PAPOLA; poly(A) polymerase alpha K14376 PAP; poly(A) polymerase [EC:2.7.7.19]
E 106549074 PAPOLG; poly(A) polymerase gamma K14376 PAP; poly(A) polymerase [EC:2.7.7.19]
E 106544494 PAPD4; poly(A) RNA polymerase GLD2 isoform X1 K14079 PAPD4; poly(A) RNA polymerase GLD2 [EC:2.7.7.19]
E 106546388 speckle targeted PIP5K1A-regulated poly(A) polymerase-like K18709 TUT1; speckle targeted PIP5K1A-regulated poly(A) polymerase [EC:2.7.7.19 2.7.7.52]
D Negative regulators of mRNA 3' end processing
E 106552234 BRCA1-associated RING domain protein 1-like K10683 BARD1; BRCA1-associated RING domain protein 1
E 106542346 RBM26; RNA-binding protein 26 K13192 RBM26; RNA-binding protein 26
E 106555520 FTO; alpha-ketoglutarate-dependent dioxygenase FTO K19469 FTO; mRNA N6-methyladenine demethylase [EC:1.14.11.53]
E 106540034 ALKBH5; RNA demethylase ALKBH5 K10767 ALKBH5; mRNA N6-methyladenine demethylase [EC:1.14.11.53]
E 106548092 TARDBP; TAR DNA-binding protein 43 isoform X1 K23600 TARDBP; TAR DNA-binding protein 43
C Other processing factors
D 106552762 methyltransferase-like protein 22 K23040 METTL22; methyltransferase-like protein 22 [EC:2.1.1.-]
D 106544006 FAM46A; protein FAM46A K23033 TENT5A_B; terminal nucleotidyltransferase 5A/B [EC:2.7.7.-]
D 106542573 protein FAM46A-like K23033 TENT5A_B; terminal nucleotidyltransferase 5A/B [EC:2.7.7.-]
D 106550813 FAM46C; protein FAM46C K23034 TENT5C; terminal nucleotidyltransferase 5C [EC:2.7.7.19]
D 106551017 protein FAM46D-like K23035 TENT5D; terminal nucleotidyltransferase 5D [EC:2.7.7.19]
D 106557017 ZC3H14; zinc finger CCCH domain-containing protein 14 K23038 ZC3H14; zinc finger CCCH domain-containing protein 14
D 106556673 serrate RNA effector molecule homolog K27103 SRRT; serrate RNA effector molecule
B mRNA surveillance and transport factors
C Transport factors
D EJC complex
E 106546274 RBM8A; RNA-binding protein 8A K12876 RBM8A; RNA-binding protein 8A
E 106546067 MAGOH; protein mago nashi homolog K12877 MAGOH; protein mago nashi
E 106544966 ALYREF; THO complex subunit 4 K12881 THOC4; THO complex subunit 4
E 106544275 LOW QUALITY PROTEIN: spliceosome RNA helicase DDX39B-like K12812 DDX39B; ATP-dependent RNA helicase UAP56/SUB2 [EC:5.6.2.7]
E 106550173 EIF4A3; eukaryotic initiation factor 4A-III K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]
E 106547947 CCDC174; coiled-coil domain-containing protein 174 K25178 CCDC174; coiled-coil domain-containing protein 174
E 106555294 CASC3; protein CASC3 isoform X1 K14323 CASC3; protein CASC3
E 106544285 SAP18; histone deacetylase complex subunit SAP18 K14324 SAP18; histone deacetylase complex subunit SAP18
E 106539382 PNN; pinin K13114 PNN; pinin
E 106556591 apoptotic chromatin condensation inducer in the nucleus-like K12875 ACIN1; apoptotic chromatin condensation inducer in the nucleus
E 106556311 ACIN1; apoptotic chromatin condensation inducer in the nucleus K12875 ACIN1; apoptotic chromatin condensation inducer in the nucleus
E 106545810 SRRM1; serine/arginine repetitive matrix protein 1 isoform X1 K13171 SRRM1; serine/arginine repetitive matrix protein 1
D TREX complex
E 106549588 THO complex subunit 2 K12879 THOC2; THO complex subunit 2
E 106548123 THOC3; THO complex subunit 3 K12880 THOC3; THO complex subunit 3
E 106544966 ALYREF; THO complex subunit 4 K12881 THOC4; THO complex subunit 4
E 106555468 THOC5; THO complex subunit 5 homolog K13174 THOC5; THO complex subunit 5
E 106543305 THOC6; THO complex subunit 6 homolog K13175 THOC6; THO complex subunit 6
E 106547219 THOC7; THO complex subunit 7 homolog K13176 THOC7; THO complex subunit 7
D TREX-2 complex
E 106543093 PCID2; PCI domain-containing protein 2 K23801 PCID2; nuclear mRNA export protein PCID2/THP1
E 106555472 ENY2; transcription and mRNA export factor ENY2 K11368 ENY2; enhancer of yellow 2 transcription factor
E 106555927 CETN2; centrin-2 K10840 CETN2; centrin-2
E 106552553 centrin-2-like K10840 CETN2; centrin-2
E 106539098 CETN3; centrin-3 K16466 CETN3; centrin-3
E 106552207 MCM3AP; germinal-center associated nuclear protein K24317 MCM3AP; germinal-center associated nuclear protein [EC:2.3.1.48]
D Nuclear pore complex
E 106550860 RAE1; mRNA export factor isoform X1 K14298 RAE1; mRNA export factor
E 106543213 SEC13; protein SEC13 homolog K14004 SEC13; protein transport protein SEC13
E 106542974 NUP37; nucleoporin Nup37 K14302 NUP37; nuclear pore complex protein Nup37
E 106551645 NUP85; nuclear pore complex protein Nup85 K14304 NUP85; nuclear pore complex protein Nup85
E 106552460 NUP43; nucleoporin Nup43 K14305 NUP43; nuclear pore complex protein Nup43
E 106543237 NUP50; nuclear pore complex protein Nup50 K14295 NUP50; nuclear pore complex protein Nup50
E 106548027 NUP54; nucleoporin p54 K14308 NUP54; nuclear pore complex protein Nup54
E 106552533 nuclear pore glycoprotein p62-like K14306 NUP62; nuclear pore complex protein Nup62
E 106553762 nuclear pore glycoprotein p62-like K14306 NUP62; nuclear pore complex protein Nup62
E 106555415 nuclear pore complex protein Nup88-like K14318 NUP88; nuclear pore complex protein Nup88
E 106552529 nuclear pore complex protein Nup93 K14309 NUP93; nuclear pore complex protein Nup93
E 106555102 nuclear pore complex protein Nup93-like K14309 NUP93; nuclear pore complex protein Nup93
E 106556747 NUP98; nuclear pore complex protein Nup98-Nup96 K14297 NUP98; nuclear pore complex protein Nup98-Nup96
E 106556277 nuclear pore complex protein Nup98-Nup96-like K14297 NUP98; nuclear pore complex protein Nup98-Nup96
E 106538067 NUP107; nuclear pore complex protein Nup107 K14301 NUP107; nuclear pore complex protein Nup107
E 106543753 NUP133; nuclear pore complex protein Nup133 K14300 NUP133; nuclear pore complex protein Nup133
E 106545109 nucleoporin NUP188 homolog K14311 NUP188; nuclear pore complex protein Nup188
E 106554439 NUP153; nuclear pore complex protein Nup153 isoform X1 K14296 NUP153; nuclear pore complex protein Nup153
E 106540019 NUP155; nuclear pore complex protein Nup155 isoform X1 K14312 NUP155; nuclear pore complex protein Nup155
E 106541380 NUP160; nuclear pore complex protein Nup160 K14303 NUP160; nuclear pore complex protein Nup160
E 106549670 NUP35; nucleoporin NUP53 isoform X1 K14313 NUP35; nuclear pore complex protein Nup53
E 106546191 NUP205; nuclear pore complex protein Nup205 K14310 NUP205; nuclear pore complex protein Nup205
E 106556342 nuclear pore complex protein Nup205-like K14310 NUP205; nuclear pore complex protein Nup205
E 106546962 NUP210L; nuclear pore membrane glycoprotein 210-like K14314 NUP210; nuclear pore complex protein Nup210
E 106546407 NUP210; nuclear pore membrane glycoprotein 210 K14314 NUP210; nuclear pore complex protein Nup210
E 106550909 NUP214; nuclear pore complex protein Nup214 K14317 NUP214; nuclear pore complex protein Nup214
E 106552640 POM121; nuclear envelope pore membrane protein POM 121 K14316 POM121; nuclear pore complex protein Nup121
E 106539114 NUP58; nucleoporin p58/p45 K14307 NUPL1; nucleoporin p58/p45
E 106540044 NUPL2; nucleoporin-like protein 2 K14321 NUPL2; nucleoporin-like protein 2
E 106540454 NDC1; nucleoporin NDC1 isoform X1 K14315 NDC1; nucleoporin NDC1
E 106545747 SEH1L; nucleoporin SEH1 isoform X1 K14299 SEH1; nucleoporin SEH1
E 106542195 RANBP2; E3 SUMO-protein ligase RanBP2 K12172 RANBP2; E3 SUMO-protein ligase RanBP2 [EC:2.3.2.-]
E 106544598 SENP2; sentrin-specific protease 2 isoform X1 K03345 SENP2; sentrin-specific protease 2 (axin associating molecule) [EC:3.4.22.68]
E 106540389 AAAS; aladin isoform X1 K14320 AAAS; aladin
E 106539098 CETN3; centrin-3 K16466 CETN3; centrin-3
E 106555214 GLE1; nucleoporin GLE1 K18723 GLE1; nucleoporin GLE1
E 106553550 nuclear RNA export factor 1-like K14284 NXF; nuclear RNA export factor
E 106548518 NXT2; NTF2-related export protein 2 isoform X1 K14285 NXT1_2; NTF2-related export protein 1/2
D Ran-mediated transport factors
E 106549752 RAN; GTP-binding nuclear protein Ran K07936 RAN; GTP-binding nuclear protein Ran
E 106555434 ANP32A; acidic leucine-rich nuclear phosphoprotein 32 family member A K18646 ANP32A_C_D; acidic leucine-rich nuclear phosphoprotein 32 family member A/C/D
E 106542162 acidic leucine-rich nuclear phosphoprotein 32 family member B-like K18647 ANP32B; acidic leucine-rich nuclear phosphoprotein 32 family member B
E 106552834 acidic leucine-rich nuclear phosphoprotein 32 family member B-like K18647 ANP32B; acidic leucine-rich nuclear phosphoprotein 32 family member B
E 106554492 ELAV-like protein 1 K13088 ELAVL1; ELAV-like protein 1
E 106544492 ELAVL2; ELAV-like protein 2 K13208 ELAVL2_3_4; ELAV like protein 2/3/4
E 106544883 ELAV-like protein 3 K13208 ELAVL2_3_4; ELAV like protein 2/3/4
E 106549090 ELAVL4; ELAV-like protein 4 isoform X1 K13208 ELAVL2_3_4; ELAV like protein 2/3/4
E 106548124 FAF2; FAS-associated factor 2 K18726 FAF2; FAS-associated factor 2
E 106554929 transitional endoplasmic reticulum ATPase-like K13525 VCP; transitional endoplasmic reticulum ATPase
E 106545950 VCPKMT; protein-lysine methyltransferase METTL21D K21806 VCPKMT; protein N-lysine methyltransferase METTL21D [EC:2.1.1.-]
E 106546398 TNPO2; transportin-2 K18727 TNPO2; transportin-2
E 106551777 XPO1; exportin-1 K14290 XPO1; exportin-1
E 106542633 XPO7; exportin-7 isoform X1 K18460 XPO7; exportin-7
E 106541127 RANBP17; ran-binding protein 17 K24115 RANBP17; Ran-binding protein 17
E 106537818 RANGAP1; ran GTPase-activating protein 1 K14319 RANGAP1; Ran GTPase-activating protein 1
E 106543041 TAF15; TATA-binding protein-associated factor 2N isoform X1 K14651 TAF15; transcription initiation factor TFIID subunit 15
D eIF4F and regulatory proteins
E 106555596 EIF4E2; eukaryotic translation initiation factor 4E type 2 K03259 EIF4E; translation initiation factor 4E
E 106537724 EIF4E1B; eukaryotic translation initiation factor 4E type 1B isoform X1 K03259 EIF4E; translation initiation factor 4E
E 106554703 EIF4E; eukaryotic translation initiation factor 4E K03259 EIF4E; translation initiation factor 4E
E 106554078 EIF4A1; eukaryotic initiation factor 4A-I K03257 EIF4A; translation initiation factor 4A
E 106550467 EIF4A2; eukaryotic initiation factor 4A-II isoform X1 K03257 EIF4A; translation initiation factor 4A
E 106549948 EIF4G1; eukaryotic translation initiation factor 4 gamma 1 K03260 EIF4G; translation initiation factor 4G
E 106537527 EIF4G2; eukaryotic translation initiation factor 4 gamma 2 K03260 EIF4G; translation initiation factor 4G
E 106551663 EIF4G3; eukaryotic translation initiation factor 4 gamma 3 K03260 EIF4G; translation initiation factor 4G
E 106552509 EIF4B; eukaryotic translation initiation factor 4B K03258 EIF4B; translation initiation factor 4B
E 106556144 EIF4H; eukaryotic translation initiation factor 4H K24086 EIF4H; translation initiation factor 4H
E 106547504 EIF4EBP1; eukaryotic translation initiation factor 4E-binding protein 1 K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
E 106540526 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter isoform X1 K18728 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter
E 106546130 ANGEL2; protein angel homolog 2 isoform X1 K18729 ANGEL; protein angel
E 106547278 ANGEL1; protein angel homolog 1 isoform X1 K18729 ANGEL; protein angel
E 106554080 FXR2; fragile X mental retardation syndrome-related protein 2 K15516 FMR; fragile X mental retardation protein
E 106545176 FXR1; fragile X mental retardation syndrome-related protein 1 K15516 FMR; fragile X mental retardation protein
E 106554661 FMR1; fragile X mental retardation protein 1 K15516 FMR; fragile X mental retardation protein
E 106554726 cytoplasmic FMR1-interacting protein 1 isoform X1 K05749 CYFIP; cytoplasmic FMR1 interacting protein
E 106555600 cytoplasmic FMR1-interacting protein 1-like K05749 CYFIP; cytoplasmic FMR1 interacting protein
E 106543520 CYFIP2; cytoplasmic FMR1-interacting protein 2 K05749 CYFIP; cytoplasmic FMR1 interacting protein
E 106548064 GEMIN5; gem-associated protein 5 K13133 GEMIN5; gem associated protein 5
E 106553304 TACC3; transforming acidic coiled-coil-containing protein 3 K14283 TACC3; transforming acidic coiled-coil-containing protein 3
E 106539439 CPEB3; cytoplasmic polyadenylation element-binding protein 3 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 106539100 CPEB4; cytoplasmic polyadenylation element-binding protein 4 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 106547835 cytoplasmic polyadenylation element-binding protein 1-like K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 106555148 ATP-dependent RNA helicase DDX3X isoform X1 K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]
E 106554448 GIGYF2; PERQ amino acid-rich with GYF domain-containing protein 2 isoform X1 K18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein
E 106556568 PERQ amino acid-rich with GYF domain-containing protein 1-like K18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein
E 106540828 PABPC1; polyadenylate-binding protein 1 isoform X1 K13126 PABPC; polyadenylate-binding protein
E 106543878 polyadenylate-binding protein 1-B-like K13126 PABPC; polyadenylate-binding protein
E 106554218 PABPC4; polyadenylate-binding protein 4 isoform X1 K13126 PABPC; polyadenylate-binding protein
E 106552993 PAIP1; polyadenylate-binding protein-interacting protein 1 K14322 PAIP1; polyadenylate-binding protein-interacting protein 1
E 106546704 PAIP2; polyadenylate-binding protein-interacting protein 2 K27470 PAIP2; polyadenylate-binding protein-interacting protein 2
E 106538284 LOW QUALITY PROTEIN: polyadenylate-binding protein-interacting protein 2B-like K27470 PAIP2; polyadenylate-binding protein-interacting protein 2
E 106544270 SKIV2L; helicase SKI2W K12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6]
E 106556107 DEAF1; deformed epidermal autoregulatory factor 1 homolog K23041 DEAF1; deformed epidermal autoregulatory factor 1
E 106556108 deformed epidermal autoregulatory factor 1 homolog K23041 DEAF1; deformed epidermal autoregulatory factor 1
E 106546082 DENR; density-regulated protein K24272 DENR; density-regulated protein
D APOBEC1-ACF complex
D Other transport factors
E 106544046 WIBG; partner of Y14 and mago K14294 WIBG; partner of Y14 and mago
E 106537555 HNRNPA3; heterogeneous nuclear ribonucleoprotein A3 isoform X1 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 106541878 HNRNPA1; heterogeneous nuclear ribonucleoprotein A1 isoform X1 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 106555833 RNA-binding protein Musashi homolog 2-like K14411 MSI; RNA-binding protein Musashi
E 106546397 DAZAP1; DAZ-associated protein 1 isoform X1 K14411 MSI; RNA-binding protein Musashi
E 106542695 MSI1; RNA-binding protein Musashi homolog 1 isoform X1 K14411 MSI; RNA-binding protein Musashi
E 106545303 HBS1L; HBS1-like protein K14416 HBS1; elongation factor 1 alpha-like protein
E 106544266 PELO; protein pelota homolog K06965 PELO; protein pelota
E 106556480 polyadenylate-binding protein 2 K14396 PABPN1; polyadenylate-binding protein 2
E 106547439 ATP-dependent RNA helicase DDX19B K18655 DDX19; ATP-dependent RNA helicase DDX19/DBP5 [EC:5.6.2.7]
E 106545575 DDX25; ATP-dependent RNA helicase DDX25 K18656 DDX25; ATP-dependent RNA helicase DDX25 [EC:5.6.2.7]
E 106543443 XAB2; pre-mRNA-splicing factor SYF1 K12867 SYF1; pre-mRNA-splicing factor SYF1
E 106550921 SARNP; SAP domain-containing ribonucleoprotein K18732 SARNP; SAP domain-containing ribonucleoprotein
E 106554187 RCC1; regulator of chromosome condensation K11493 RCC1; regulator of chromosome condensation
E 106542036 LARP6; la-related protein 6 K18733 LARP6; la-related protein 6
E 106547624 la-related protein 6-like K18733 LARP6; la-related protein 6
E 106543433 PURA; transcriptional activator protein Pur-alpha K21772 PURA; transcriptional activator protein Pur-alpha
E 106548212 PURB; transcriptional activator protein Pur-beta K21799 PURB; transcriptional activator protein Pur-beta
E 106537799 POLDIP3; polymerase delta-interacting protein 3 isoform X1 K22414 POLDIP3; polymerase delta-interacting protein 3
E 106557110 zinc finger CCCH domain-containing protein 11A-like K22415 ZC3H11; zinc finger CCCH domain-containing protein 11
E 106557111 zinc finger CCCH domain-containing protein 11A-like K22415 ZC3H11; zinc finger CCCH domain-containing protein 11
E 106548412 LENG8; leukocyte receptor cluster member 8 isoform X1 K23802 LENG8; SAC3 family protein LENG8/THP3
C Surveillance factors
D Surveillance complex
E 106549004 ETF1; eukaryotic peptide chain release factor subunit 1 K03265 ETF1; peptide chain release factor subunit 1
E 106539913 eukaryotic peptide chain release factor GTP-binding subunit ERF3A K03267 ERF3; peptide chain release factor subunit 3
E 106543970 UPF1; regulator of nonsense transcripts 1 isoform X1 K14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3]
E 106555661 UPF2; regulator of nonsense transcripts 2 K14327 UPF2; regulator of nonsense transcripts 2
E 106549163 UPF3B; regulator of nonsense transcripts 3B isoform X1 K14328 UPF3; regulator of nonsense transcripts 3
E 106546012 UPF3A; regulator of nonsense transcripts 3A isoform X1 K14328 UPF3; regulator of nonsense transcripts 3
D Protein phosphatase 2A
E 106539819 PPP2CB; serine/threonine-protein phosphatase 2A catalytic subunit beta isoform K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
E 106539522 serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
E 106546744 PPP2R1A; serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
E 106544475 serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
E 106542078 serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
E 106555957 PPP2R2A; serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
E 106543000 PPP2R2B; serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
E 106555030 PPP2R3C; serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
E 106539930 PPP2R3B; serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta isoform X1 K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
E 106538381 serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha-like K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
E 106538393 PPP2R3A; serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
E 106538010 PPP2R5D; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform isoform X1 K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
E 106540859 serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
E 106546838 PPP2R5E; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
E 106557134 PPP2R5C; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform X1 K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
E 106552829 PPP2R5A; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
D Other surveillance factors
E 106540041 SMG1; serine/threonine-protein kinase SMG1 K08873 SMG1; serine/threonine-protein kinase SMG1 [EC:2.7.11.1]
E 106540042 serine/threonine-protein kinase SMG1-like K08873 SMG1; serine/threonine-protein kinase SMG1 [EC:2.7.11.1]
E 106551872 SMG5; protein SMG5 K11125 SMG5; protein SMG5
E 106539513 telomerase-binding protein EST1A-like K11124 SMG6; protein SMG6 [EC:3.1.-.-]
E 106556051 protein SMG7 K14409 SMG7; protein SMG7
E 106554050 SMG8; protein SMG8 K18734 SMG8; protein SMG8
E 106554448 GIGYF2; PERQ amino acid-rich with GYF domain-containing protein 2 isoform X1 K18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein
E 106556568 PERQ amino acid-rich with GYF domain-containing protein 1-like K18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein
E 106543851 SECISBP2; selenocysteine insertion sequence-binding protein 2 isoform X1 K19539 SECISBP2; selenocysteine insertion sequence-binding protein 2
E 106554010 selenocysteine insertion sequence-binding protein 2-like K19539 SECISBP2; selenocysteine insertion sequence-binding protein 2
E 106540612 DHX34; probable ATP-dependent RNA helicase DHX34 isoform X1 K20101 DHX34; ATP-dependent RNA helicase DHX34 [EC:5.6.2.6]
E 106540141 GTPBP1; GTP-binding protein 1 isoform X1 K24887 GTPBP1; GTP-binding protein 1
C Factors involved in mRNA localization
D Cargo complex
E 106547359 pumilio domain-containing protein KIAA0020 homolog K14844 PUF6; pumilio homology domain family member 6
E 106540578 MYO5A; unconventional myosin-Va K10357 MYO5; myosin V
E 106540588 MYO5C; unconventional myosin-Vc K10357 MYO5; myosin V
E 106545856 MYO5B; unconventional myosin-Vb K10357 MYO5; myosin V
E 106545936 unconventional myosin-Va-like K10357 MYO5; myosin V
E 106541461 BICD2; protein bicaudal D homolog 2 isoform X1 K18739 BICD; protein bicaudal D
E 106538579 BICD1; protein bicaudal D homolog 1 K18739 BICD; protein bicaudal D
E 106555360 protein bicaudal D homolog 2-like K18739 BICD; protein bicaudal D
E 106542325 EXD1; exonuclease 3'-5' domain-containing protein 1 isoform X1 K18740 EXD1; exonuclease 3'-5' domain-containing protein 1
D Factors that have mRNA localization signals
E 106548496 actin, cytoplasmic 2 K05692 ACTB_G1; actin beta/gamma 1
E 106554285 MBP; myelin basic protein K17269 MBP; myelin basic protein
E 106543586 VIM; vimentin K07606 VIM; vimentin
E 106554587 metallothionein-1-like K14739 MT1_2; metallothionein 1/2
E 106542510 MYC; myc proto-oncogene protein K04377 MYC; Myc proto-oncogene protein
E 106543858 derriere protein-like K05495 GDF1; growth differentiation factor 1
E 106554847 T-box transcription factor TBX6-like K10180 TBX6; T-box protein 6
E 106546546 T-box transcription factor TBX6-like K10180 TBX6; T-box protein 6
D Trans-acting binding proteins
E 106551332 FUBP1; far upstream element-binding protein 1 isoform X1 K13210 FUBP; far upstream element-binding protein
E 106540006 elongation factor 1-alpha 1 K03231 EEF1A; elongation factor 1-alpha
E 106555238 elongation factor 1-alpha 2 K03231 EEF1A; elongation factor 1-alpha
E 106550148 LOW QUALITY PROTEIN: elongation factor 1-gamma-like K03233 EEF1G; elongation factor 1-gamma
E 106550105 HNRNPA2B1; heterogeneous nuclear ribonucleoproteins A2/B1 K13158 HNRNPA2B1; heterogeneous nuclear ribonucleoprotein A2/B1
E 106541630 AGFG1; arf-GAP domain and FG repeat-containing protein 1 isoform X1 K15044 AGFG1; Arf-GAP domain and FG repeats-containing protein 1
E 106539560 STAU1; double-stranded RNA-binding protein Staufen homolog 1 isoform X1 K17597 STAU; double-stranded RNA-binding protein Staufen
E 106539981 IGF2BP3; insulin-like growth factor 2 mRNA-binding protein 3 isoform X1 K13197 IGF2BP3; insulin-like growth factor 2 mRNA-binding protein 3
E 106554157 PTBP1; polypyrimidine tract-binding protein 1 K13218 PTBP1; polypyrimidine tract-binding protein 1
E 106539439 CPEB3; cytoplasmic polyadenylation element-binding protein 3 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 106539100 CPEB4; cytoplasmic polyadenylation element-binding protein 4 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 106547835 cytoplasmic polyadenylation element-binding protein 1-like K02602 CPEB; cytoplasmic polyadenylation element-binding protein
D Other mRNA localization factors
E 106554080 FXR2; fragile X mental retardation syndrome-related protein 2 K15516 FMR; fragile X mental retardation protein
E 106545176 FXR1; fragile X mental retardation syndrome-related protein 1 K15516 FMR; fragile X mental retardation protein
E 106554661 FMR1; fragile X mental retardation protein 1 K15516 FMR; fragile X mental retardation protein
E 106554726 cytoplasmic FMR1-interacting protein 1 isoform X1 K05749 CYFIP; cytoplasmic FMR1 interacting protein
E 106555600 cytoplasmic FMR1-interacting protein 1-like K05749 CYFIP; cytoplasmic FMR1 interacting protein
E 106543520 CYFIP2; cytoplasmic FMR1-interacting protein 2 K05749 CYFIP; cytoplasmic FMR1 interacting protein
E 106549756 PCBP2; poly(rC)-binding protein 2 isoform X1 K13162 PCBP2; poly(rC)-binding protein 2
E 106547398 PCBP3; poly(rC)-binding protein 3 K21444 PCBP3_4; poly(rC)-binding protein 3/4
E 106546950 PCBP4; poly(rC)-binding protein 4 K21444 PCBP3_4; poly(rC)-binding protein 3/4
E 106556892 CAPRIN1; caprin-1 K18743 CAPRIN1; caprin-1
E 106553800 CAPRIN2; caprin-2 isoform X1 K18744 CAPRIN2; caprin-2
E 106552969 YBX1; nuclease-sensitive element-binding protein 1 isoform X1 K09276 YBX1; Y-box-binding protein 1
C mRNA cycle factors
D Common to processing body (P body) and stress granule
E 106539914 XRN1; 5'-3' exoribonuclease 1 isoform X1 K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]
E 106555754 protein argonaute-3 isoform X1 K11593 ELF2C; eukaryotic translation initiation factor 2C
E 106540691 AGO4; protein argonaute-4 K11593 ELF2C; eukaryotic translation initiation factor 2C
E 106550791 protein argonaute-1 K11593 ELF2C; eukaryotic translation initiation factor 2C
E 106554637 protein argonaute-2 K11593 ELF2C; eukaryotic translation initiation factor 2C
E 106555596 EIF4E2; eukaryotic translation initiation factor 4E type 2 K03259 EIF4E; translation initiation factor 4E
E 106537724 EIF4E1B; eukaryotic translation initiation factor 4E type 1B isoform X1 K03259 EIF4E; translation initiation factor 4E
E 106554703 EIF4E; eukaryotic translation initiation factor 4E K03259 EIF4E; translation initiation factor 4E
E 106543970 UPF1; regulator of nonsense transcripts 1 isoform X1 K14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3]
E 106555148 ATP-dependent RNA helicase DDX3X isoform X1 K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]
E 106540651 DDX6; probable ATP-dependent RNA helicase DDX6 K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7]
E 106554564 MEX3C; RNA-binding E3 ubiquitin-protein ligase MEX3C K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
E 106550604 MEX3D; RNA-binding protein MEX3D K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
E 106557192 MEX3A; RNA-binding protein MEX3A K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
E 106556394 MEX3B; RNA-binding protein MEX3B K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
E 106545258 LSM14B; protein LSM14 homolog B isoform X1 K18749 LSM14; protein LSM14
E 106557347 LSM14A; protein LSM14 homolog A K18749 LSM14; protein LSM14
E 106554021 protein LSM14 homolog A-like isoform X1 K18749 LSM14; protein LSM14
E 106549756 PCBP2; poly(rC)-binding protein 2 isoform X1 K13162 PCBP2; poly(rC)-binding protein 2
E 106552969 YBX1; nuclease-sensitive element-binding protein 1 isoform X1 K09276 YBX1; Y-box-binding protein 1
E 106552715 LIMD1; LIM domain-containing protein 1 K16682 AJUBA; LIM domain-containing protein
E 106556148 Wilms tumor protein 1-interacting protein homolog K16682 AJUBA; LIM domain-containing protein
E 106548883 MOV10; putative helicase MOV-10 K18422 MOV10; helicase MOV-10 [EC:5.6.2.5]
E 106551016 PNRC2; proline-rich nuclear receptor coactivator 2 K18751 PNRC2; proline-rich nuclear receptor coactivator 2
E 106549606 TNPO1; transportin-1 K18752 TNPO1; transportin-1
E 106540041 SMG1; serine/threonine-protein kinase SMG1 K08873 SMG1; serine/threonine-protein kinase SMG1 [EC:2.7.11.1]
E 106540042 serine/threonine-protein kinase SMG1-like K08873 SMG1; serine/threonine-protein kinase SMG1 [EC:2.7.11.1]
E 106551872 SMG5; protein SMG5 K11125 SMG5; protein SMG5
E 106539513 telomerase-binding protein EST1A-like K11124 SMG6; protein SMG6 [EC:3.1.-.-]
E 106556051 protein SMG7 K14409 SMG7; protein SMG7
E 106539600 ZFP36L1; zinc finger protein 36, C3H1 type-like 1 isoform X1 K18753 ZFP36L; butyrate response factor
E 106539403 ZFP36L2; zinc finger protein 36, C3H1 type-like 2 K18753 ZFP36L; butyrate response factor
E 106553787 LIN28B; protein lin-28 homolog B K18754 LIN28; protein lin-28
E 106547070 LIN28A; protein lin-28 homolog A K18754 LIN28; protein lin-28
E 106557327 IPO8; importin-8 K18755 IPO8; importin-8
E 106539416 BICC1; protein bicaudal C homolog 1 K18756 BICC1; protein bicaudal C
E 106537555 HNRNPA3; heterogeneous nuclear ribonucleoprotein A3 isoform X1 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 106541878 HNRNPA1; heterogeneous nuclear ribonucleoprotein A1 isoform X1 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 106555867 cAMP-dependent protein kinase catalytic subunit beta isoform X1 K04345 PKA; protein kinase A [EC:2.7.11.11]
E 106544707 cAMP-dependent protein kinase catalytic subunit alpha-like K04345 PKA; protein kinase A [EC:2.7.11.11]
E 106552921 la-related protein 1B-like K18757 LARP1; la-related protein 1
E 106546686 LARP1B; la-related protein 1B isoform X1 K18757 LARP1; la-related protein 1
E 106547737 LARP1; la-related protein 1 isoform X1 K18757 LARP1; la-related protein 1
D P-body specific factors
E 106540736 DCP2; m7GpppN-mRNA hydrolase isoform X1 K12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]
E 106541464 DCP1A; mRNA-decapping enzyme 1A K12610 DCP1A; mRNA-decapping enzyme 1A [EC:3.-.-.-]
E 106540690 DCP1B; mRNA-decapping enzyme 1B K12611 DCP1B; mRNA-decapping enzyme 1B [EC:3.-.-.-]
E 106555659 LSM1; U6 snRNA-associated Sm-like protein LSm1 K12620 LSM1; U6 snRNA-associated Sm-like protein LSm1
E 106554150 LSM2; U6 snRNA-associated Sm-like protein LSm2 K12621 LSM2; U6 snRNA-associated Sm-like protein LSm2
E 106549425 LSM3; U6 snRNA-associated Sm-like protein LSm3 K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3
E 106539455 LSM5; U6 snRNA-associated Sm-like protein LSm5 K12624 LSM5; U6 snRNA-associated Sm-like protein LSm5
E 106543348 LSM6; U6 snRNA-associated Sm-like protein LSm6 K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6
E 106553843 LSM7; U6 snRNA-associated Sm-like protein LSm7 K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7
E 106551308 LSM8; LSM8 homolog, U6 small nuclear RNA associated K12627 LSM8; U6 snRNA-associated Sm-like protein LSm8
E 106543546 kinesin light chain 1-like K10407 KLC; kinesin light chain
E 106539710 kinesin light chain 1 isoform X1 K10407 KLC; kinesin light chain
E 106539311 kinesin light chain 1-like K10407 KLC; kinesin light chain
E 106555796 kinesin light chain 3-like K10407 KLC; kinesin light chain
E 106554276 kinesin light chain 1-like K10407 KLC; kinesin light chain
E 106540578 MYO5A; unconventional myosin-Va K10357 MYO5; myosin V
E 106540588 MYO5C; unconventional myosin-Vc K10357 MYO5; myosin V
E 106545856 MYO5B; unconventional myosin-Vb K10357 MYO5; myosin V
E 106545936 unconventional myosin-Va-like K10357 MYO5; myosin V
E 106545766 tubulin alpha-1A chain K07374 TUBA; tubulin alpha
E 106556095 tubulin alpha-3 chain K07374 TUBA; tubulin alpha
E 106545017 tubulin alpha-8 chain-like K07374 TUBA; tubulin alpha
E 106540316 tubulin alpha-4A chain K07374 TUBA; tubulin alpha
E 106543324 tubulin alpha-8 chain K07374 TUBA; tubulin alpha
E 106546597 tubulin alpha-1B chain-like K07374 TUBA; tubulin alpha
E 106546598 tubulin alpha chain-like K07374 TUBA; tubulin alpha
E 106546601 tubulin alpha-1C chain K07374 TUBA; tubulin alpha
E 106550675 tubulin alpha-3 chain K07374 TUBA; tubulin alpha
E 106539439 CPEB3; cytoplasmic polyadenylation element-binding protein 3 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 106539100 CPEB4; cytoplasmic polyadenylation element-binding protein 4 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 106547835 cytoplasmic polyadenylation element-binding protein 1-like K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 106548064 GEMIN5; gem-associated protein 5 K13133 GEMIN5; gem associated protein 5
E 106553304 TACC3; transforming acidic coiled-coil-containing protein 3 K14283 TACC3; transforming acidic coiled-coil-containing protein 3
E 106544909 TNRC6B; trinucleotide repeat-containing gene 6B protein isoform X1 K18412 TNRC6; trinucleotide repeat-containing gene 6 protein
E 106557285 TNRC6C; trinucleotide repeat-containing gene 6C protein K18412 TNRC6; trinucleotide repeat-containing gene 6 protein
E 106541939 TNRC6A; trinucleotide repeat-containing gene 6A protein isoform X1 K18412 TNRC6; trinucleotide repeat-containing gene 6 protein
E 106549362 CNOT1; CCR4-NOT transcription complex subunit 1 K12604 CNOT1; CCR4-NOT transcription complex subunit 1
E 106552435 CNOT2; CCR4-NOT transcription complex subunit 2 isoform X1 K12605 CNOT2; CCR4-NOT transcription complex subunit 2
E 106538830 CCR4-NOT transcription complex subunit 3-like K12580 CNOT3; CCR4-NOT transcription complex subunit 3
E 106549081 CNOT3; CCR4-NOT transcription complex subunit 3 K12580 CNOT3; CCR4-NOT transcription complex subunit 3
E 106554103 CCR4-NOT transcription complex subunit 3-like K12580 CNOT3; CCR4-NOT transcription complex subunit 3
E 106552290 CNOT4; CCR4-NOT transcription complex subunit 4 isoform X1 K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]
E 106555922 CCR4-NOT transcription complex subunit 6 K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E 106548109 CNOT6; CCR4-NOT transcription complex subunit 6 K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E 106550318 CNOT6L; CCR4-NOT transcription complex subunit 6-like K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E 106538549 CNOT7; CCR4-NOT transcription complex subunit 7 isoform X1 K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E 106548063 CNOT8; CCR4-NOT transcription complex subunit 8 K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E 106557338 uncharacterized protein KIAA0355 homolog K26671 GARRE1; granule associated Rac and RHOG effector protein 1
E 106557177 uncharacterized protein KIAA0355-like K26671 GARRE1; granule associated Rac and RHOG effector protein 1
E 106544442 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit PAN2 K12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4]
E 106550428 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit PAN3 K12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3
E 106541141 BTG1; protein BTG1 K14443 TOB; protein Tob/BTG
E 106542450 BTG2; protein BTG2 K14443 TOB; protein Tob/BTG
E 106537816 TOB2; protein Tob2 K14443 TOB; protein Tob/BTG
E 106543766 protein Tob1 K14443 TOB; protein Tob/BTG
E 106541339 TOB1; protein Tob1 K14443 TOB; protein Tob/BTG
E 106548021 protein BTG1-like K14443 TOB; protein Tob/BTG
E 106540526 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter isoform X1 K18728 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter
E 106542657 PATL1; protein PAT1 homolog 1 K12617 PATL1; DNA topoisomerase 2-associated protein PAT1
E 106552309 EDC4; enhancer of mRNA-decapping protein 4 K12616 EDC4; enhancer of mRNA-decapping protein 4
E 106538210 NANOS2; nanos homolog 2 K18760 NANOS2; protein nanos 2
E 106544039 nanos homolog 3-like K18761 NANOS3; protein nanos 3
E 106555661 UPF2; regulator of nonsense transcripts 2 K14327 UPF2; regulator of nonsense transcripts 2
E 106549163 UPF3B; regulator of nonsense transcripts 3B isoform X1 K14328 UPF3; regulator of nonsense transcripts 3
E 106546012 UPF3A; regulator of nonsense transcripts 3A isoform X1 K14328 UPF3; regulator of nonsense transcripts 3
E 106538336 TRIM71; E3 ubiquitin-protein ligase TRIM71 K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
E 106538810 POLR2G; DNA-directed RNA polymerase II subunit RPB7 K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7
E 106550253 ZAR1L; ZAR1-like protein K18762 ZAR1; zygote arrest protein 1
E 106552019 zygote arrest protein 1-like K18762 ZAR1; zygote arrest protein 1
E 106537590 YTHDF2; YTH domain-containing family protein 2 K20102 YTHDF; YTH domain-containing family protein
E 106543962 YTHDF3; YTH domain-containing family protein 3 isoform X1 K20102 YTHDF; YTH domain-containing family protein
D Stress granule specific factors
E 106544345 nucleolysin TIA-1 isoform p40 K13201 TIA1; nucleolysin TIA-1/TIAR
E 106542620 nucleolysin TIA-1 isoform p40-like isoform X1 K13201 TIA1; nucleolysin TIA-1/TIAR
E 106549499 TIAL1; nucleolysin TIAR isoform X1 K13201 TIA1; nucleolysin TIA-1/TIAR
E 106540828 PABPC1; polyadenylate-binding protein 1 isoform X1 K13126 PABPC; polyadenylate-binding protein
E 106543878 polyadenylate-binding protein 1-B-like K13126 PABPC; polyadenylate-binding protein
E 106554218 PABPC4; polyadenylate-binding protein 4 isoform X1 K13126 PABPC; polyadenylate-binding protein
E 106539560 STAU1; double-stranded RNA-binding protein Staufen homolog 1 isoform X1 K17597 STAU; double-stranded RNA-binding protein Staufen
E 106554080 FXR2; fragile X mental retardation syndrome-related protein 2 K15516 FMR; fragile X mental retardation protein
E 106545176 FXR1; fragile X mental retardation syndrome-related protein 1 K15516 FMR; fragile X mental retardation protein
E 106554661 FMR1; fragile X mental retardation protein 1 K15516 FMR; fragile X mental retardation protein
E 106554492 ELAV-like protein 1 K13088 ELAVL1; ELAV-like protein 1
E 106546286 G3BP1; ras GTPase-activating protein-binding protein 1 isoform X1 K17265 G3BP1; Ras GTPase-activating protein-binding protein 1 [EC:5.6.2.5 5.6.2.3]
E 106550297 G3BP2; ras GTPase-activating protein-binding protein 2 isoform X1 K24983 G3BP2; Ras GTPase-activating protein-binding protein 2
E 106553896 EIF2A; eukaryotic translation initiation factor 2A K15026 EIF2A; translation initiation factor 2A
E 106557302 EIF3B; eukaryotic translation initiation factor 3 subunit B K03253 EIF3B; translation initiation factor 3 subunit B
E 106554078 EIF4A1; eukaryotic initiation factor 4A-I K03257 EIF4A; translation initiation factor 4A
E 106550467 EIF4A2; eukaryotic initiation factor 4A-II isoform X1 K03257 EIF4A; translation initiation factor 4A
E 106550173 EIF4A3; eukaryotic initiation factor 4A-III K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]
E 106552509 EIF4B; eukaryotic translation initiation factor 4B K03258 EIF4B; translation initiation factor 4B
E 106549948 EIF4G1; eukaryotic translation initiation factor 4 gamma 1 K03260 EIF4G; translation initiation factor 4G
E 106537527 EIF4G2; eukaryotic translation initiation factor 4 gamma 2 K03260 EIF4G; translation initiation factor 4G
E 106551663 EIF4G3; eukaryotic translation initiation factor 4 gamma 3 K03260 EIF4G; translation initiation factor 4G
E 106541750 RPS6KA3; ribosomal protein S6 kinase alpha-3 K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E 106556931 ribosomal protein S6 kinase alpha-2 K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E 106553190 ribosomal protein S6 kinase alpha-3 isoform X1 K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E 106546185 RPS6KA1; ribosomal protein S6 kinase alpha-1 K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E 106554238 GNB2L1; guanine nucleotide-binding protein subunit beta-2-like 1 K14753 RACK1; guanine nucleotide-binding protein subunit beta-2-like 1 protein
E 106541963 TRAF2; TNF receptor-associated factor 2 K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
E 106553550 nuclear RNA export factor 1-like K14284 NXF; nuclear RNA export factor
E 106537432 TDRD3; tudor domain-containing protein 3 K18404 TDRD3; tudor domain-containing protein 3
E 106541311 LARP4B; la-related protein 4B isoform X1 K18763 LARP4; la-related protein 4
E 106545287 LARP4; la-related protein 4 isoform X1 K18763 LARP4; la-related protein 4
B mRNA degradation factors
C 5'-3' decay
D Decapping complex
E 106541464 DCP1A; mRNA-decapping enzyme 1A K12610 DCP1A; mRNA-decapping enzyme 1A [EC:3.-.-.-]
E 106540690 DCP1B; mRNA-decapping enzyme 1B K12611 DCP1B; mRNA-decapping enzyme 1B [EC:3.-.-.-]
E 106540736 DCP2; m7GpppN-mRNA hydrolase isoform X1 K12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]
E 106540651 DDX6; probable ATP-dependent RNA helicase DDX6 K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7]
E 106552309 EDC4; enhancer of mRNA-decapping protein 4 K12616 EDC4; enhancer of mRNA-decapping protein 4
E 106542657 PATL1; protein PAT1 homolog 1 K12617 PATL1; DNA topoisomerase 2-associated protein PAT1
D Lsm complex
E 106555659 LSM1; U6 snRNA-associated Sm-like protein LSm1 K12620 LSM1; U6 snRNA-associated Sm-like protein LSm1
E 106554150 LSM2; U6 snRNA-associated Sm-like protein LSm2 K12621 LSM2; U6 snRNA-associated Sm-like protein LSm2
E 106549425 LSM3; U6 snRNA-associated Sm-like protein LSm3 K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3
E 106539455 LSM5; U6 snRNA-associated Sm-like protein LSm5 K12624 LSM5; U6 snRNA-associated Sm-like protein LSm5
E 106543348 LSM6; U6 snRNA-associated Sm-like protein LSm6 K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6
E 106553843 LSM7; U6 snRNA-associated Sm-like protein LSm7 K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7
E 106551308 LSM8; LSM8 homolog, U6 small nuclear RNA associated K12627 LSM8; U6 snRNA-associated Sm-like protein LSm8
D 5' exonucleases
E 106539914 XRN1; 5'-3' exoribonuclease 1 isoform X1 K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]
E 106552193 XRN2; 5'-3' exoribonuclease 2 K12619 XRN2; 5'-3' exoribonuclease 2 [EC:3.1.13.-]
E 106552430 U8 snoRNA-decapping enzyme-like K16855 NUDT16; U8 snoRNA-decapping enzyme [EC:3.6.1.62 3.6.1.64]
D Other 5'-3' decay factors
E 106556634 m7GpppX diphosphatase-like K12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]
E 106542960 HELZ; probable helicase with zinc finger domain K25168 HELZ; helicase with zinc finger domain [EC:5.6.2.-]
C 3'-5' decay
D Core exosome factors
E 106549027 EXOSC1; exosome complex component CSL4 K07573 CSL4; exosome complex component CSL4
E 106553297 EXOSC2; exosome complex component RRP4 K03679 RRP4; exosome complex component RRP4
E 106537506 EXOSC3; exosome complex component RRP40 K03681 RRP40; exosome complex component RRP40
E 106550244 EXOSC4; exosome complex component RRP41 K11600 RRP41; exosome complex component RRP41
E 106552876 EXOSC6; exosome complex component MTR3 K12587 MTR3; exosome complex component MTR3
E 106548739 EXOSC7; exosome complex component RRP42 K12589 RRP42; exosome complex component RRP42
E 106542153 EXOSC8; exosome complex component RRP43 K12586 RRP43; exosome complex component RRP43
E 106549538 EXOSC9; exosome complex component RRP45 isoform X1 K03678 RRP45; exosome complex component RRP45
D Exosome cofactors
E 106541282 DIS3L; DIS3-like exonuclease 1 K18681 DIS3L; DIS3-like exonuclease 1 [EC:3.1.13.-]
E 106555783 exosome component 10-like K12591 RRP6; exosome complex exonuclease RRP6 [EC:3.1.13.-]
E 106545822 C1D; nuclear nucleic acid-binding protein C1D isoform X1 K12592 C1D; exosome complex protein LRP1
D TRAMP complex
E 106552635 PAPD7; non-canonical poly(A) RNA polymerase PAPD7 isoform X1 K03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19]
E 106555026 non-canonical poly(A) RNA polymerase PAPD5-like K03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19]
E 106537455 ZCCHC7; zinc finger CCHC domain-containing protein 7 K12597 AIR1_2; protein AIR1/2
E 106546042 SKIV2L2; superkiller viralicidic activity 2-like 2 K12598 MTR4; ATP-dependent RNA helicase DOB1 [EC:5.6.2.6]
D Ski complex
E 106544270 SKIV2L; helicase SKI2W K12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6]
E 106550113 tetratricopeptide repeat protein 37-like K12600 SKI3; superkiller protein 3
E 106548911 WDR61; WD repeat-containing protein 61 K12602 WDR61; WD repeat-containing protein 61
D Ccr4-NOT complex
E 106555922 CCR4-NOT transcription complex subunit 6 K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E 106548109 CNOT6; CCR4-NOT transcription complex subunit 6 K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E 106550318 CNOT6L; CCR4-NOT transcription complex subunit 6-like K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E 106549362 CNOT1; CCR4-NOT transcription complex subunit 1 K12604 CNOT1; CCR4-NOT transcription complex subunit 1
E 106552435 CNOT2; CCR4-NOT transcription complex subunit 2 isoform X1 K12605 CNOT2; CCR4-NOT transcription complex subunit 2
E 106538830 CCR4-NOT transcription complex subunit 3-like K12580 CNOT3; CCR4-NOT transcription complex subunit 3
E 106549081 CNOT3; CCR4-NOT transcription complex subunit 3 K12580 CNOT3; CCR4-NOT transcription complex subunit 3
E 106554103 CCR4-NOT transcription complex subunit 3-like K12580 CNOT3; CCR4-NOT transcription complex subunit 3
E 106552290 CNOT4; CCR4-NOT transcription complex subunit 4 isoform X1 K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]
E 106538549 CNOT7; CCR4-NOT transcription complex subunit 7 isoform X1 K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E 106548063 CNOT8; CCR4-NOT transcription complex subunit 8 K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E 106554647 RQCD1; cell differentiation protein RCD1 homolog K12606 RCD1; CCR4-NOT transcription complex subunit 9
E 106538348 CNOT10; CCR4-NOT transcription complex subunit 10 K12607 CNOT10; CCR4-NOT transcription complex subunit 10
D Pan complex
E 106544442 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit PAN2 K12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4]
E 106550428 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit PAN3 K12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3
D Other 3'-5' decay factors
E 106551929 PARN; poly(A)-specific ribonuclease PARN K01148 PARN; poly(A)-specific ribonuclease [EC:3.1.13.4]
E 106537701 PNLDC1; poly(A)-specific ribonuclease PARN-like domain-containing protein 1 K01148 PARN; poly(A)-specific ribonuclease [EC:3.1.13.4]
E 106548643 DHX36; ATP-dependent RNA helicase DHX36 K14442 DHX36; ATP-dependent RNA helicase DHX36 [EC:5.6.2.6]
E 106541141 BTG1; protein BTG1 K14443 TOB; protein Tob/BTG
E 106542450 BTG2; protein BTG2 K14443 TOB; protein Tob/BTG
E 106537816 TOB2; protein Tob2 K14443 TOB; protein Tob/BTG
E 106543766 protein Tob1 K14443 TOB; protein Tob/BTG
E 106541339 TOB1; protein Tob1 K14443 TOB; protein Tob/BTG
E 106548021 protein BTG1-like K14443 TOB; protein Tob/BTG
E 106545270 NOCT; nocturnin isoform X1 K18764 NOCT; nocturnin [EC:3.1.3.108]
E 106545620 ERI1; 3'-5' exoribonuclease 1 K18416 THEX1; 3'-5' exoribonuclease 1 [EC:3.1.-.-]
E 106551724 ERI2; ERI1 exoribonuclease 2 K18417 ERI2; ERI1 exoribonuclease 2 [EC:3.1.-.-]
E 106556634 m7GpppX diphosphatase-like K12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]
E 106541670 PDE12; 2',5'-phosphodiesterase 12 K19612 PDE12; 2',5'-phosphodiesterase [EC:3.1.13.4 3.1.4.-]
E 106542960 HELZ; probable helicase with zinc finger domain K25168 HELZ; helicase with zinc finger domain [EC:5.6.2.-]
E 106553193 helicase with zinc finger domain 2-like K25165 HELZ2; 3'-5' exoribonuclease HELZ2 [EC:3.1.13.1 5.6.2.6]
E 106540109 NRDE2; protein NRDE2 homolog isoform X1 K26109 NRDE2; nuclear exosome regulator NRDE2
E 106539856 SAMD4A; protein Smaug homolog 1 K27396 SMG; protein Smaug
E 106542111 FOCAD; focadhesin K27498 FOCAD; focadhesin
C Other degradation factors
D RNases
E 106543866 ZC3H12C; probable ribonuclease ZC3H12C K18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]
E 106544648 ZC3H12B; probable ribonuclease ZC3H12B K18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]
E 106546914 probable ribonuclease ZC3H12B K18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]
E 106549850 ZC3H12A; ribonuclease ZC3H12A K18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]
E 106552459 ZC3H12D; probable ribonuclease ZC3H12D K18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]
#
AProkaryotic type
B Bacterial mRNA degradation factors
C RNA degradosome components
D Ribonucreases
E 106555491 REXO2; oligoribonuclease, mitochondrial K13288 orn; oligoribonuclease [EC:3.1.-.-]
D Helicases
D Other RNA degradosome components
E 106556629 ENO3; beta-enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
E 106555232 gamma-enolase-like K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
E 106540091 polyribonucleotide nucleotidyltransferase 1, mitochondrial-like K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
E 106552271 PFKM; ATP-dependent 6-phosphofructokinase, muscle type K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
E 106543787 PFKP; ATP-dependent 6-phosphofructokinase, platelet type K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
E 106537603 PFKL; ATP-dependent 6-phosphofructokinase, liver type K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
C Other RNA degradation factors
D Chaperones
E 106549003 HSPA9; stress-70 protein, mitochondrial K04043 dnaK; molecular chaperone DnaK
E 106538306 HSPD1; 60 kDa heat shock protein, mitochondrial K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D Others
D Bacterial Small RNA Regulators
B Archeal mRNA degradation factors
C Exosome components
D Core exosome
E 106553297 EXOSC2; exosome complex component RRP4 K03679 RRP4; exosome complex component RRP4
E 106549027 EXOSC1; exosome complex component CSL4 K07573 CSL4; exosome complex component CSL4
D Cofactors
E 106550244 EXOSC4; exosome complex component RRP41 K11600 RRP41; exosome complex component RRP41
E 106548739 EXOSC7; exosome complex component RRP42 K12589 RRP42; exosome complex component RRP42
D Others
!
#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: April 25, 2024