+C Peptidases and inhibitors KO
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Peptidases and Inhibitors - Anaeromyxobacter dehalogenans 2CP-1
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AAspartic peptidases
B Family A1: pepsin family
B Family A2: retropepsin family
B Family A5: thermopsin family
B Family A8: signal peptidase II family
C A2cp1_0013 lipoprotein signal peptidase K03101 lspA; signal peptidase II [EC:3.4.23.36]
B Family A22: presenilin family
B Family A24: type IV prepilin peptidase family
C A2cp1_0671 peptidase A24A domain protein K02654 pilD; leader peptidase (prepilin peptidase) / N-methyltransferase [EC:3.4.23.43 2.1.1.-]
C A2cp1_3004 peptidase A24A prepilin type IV K02278 cpaA; prepilin peptidase CpaA [EC:3.4.23.43]
B Family A25: gpr protease family
B Family A26: omptin family
B Family A28
B Family A31: HybD endopeptidase family
C A2cp1_0505 hydrogenase maturation protease K03605 hyaD; hydrogenase maturation protease [EC:3.4.23.-]
C A2cp1_4313 hydrogenase maturation protease K03605 hyaD; hydrogenase maturation protease [EC:3.4.23.-]
C A2cp1_3043 hydrogenase maturation protease K03605 hyaD; hydrogenase maturation protease [EC:3.4.23.-]
B Family A36
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ACysteine peptidases
B Family C1: papain family
B Family C2: calpain family
B Family C3: picornain family
B Family C4: NIa protease family
B Family C5
B Family C9
B Family C10: streptopain family
B Family C11: clostripain family
B Family C12: ubiquitin C-terminal hydrolase family
B Family C13: legumain family
B Family C14: caspase family
B Family C15: pyroglutamyl peptidase I family
B Family C16
B Family C19: ubiquitin-specific protease family
B Family C25: gingipain family
B Family C26: gamma-glutamyl hydrolase family
C A2cp1_1616 GMP synthase, large subunit K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
C A2cp1_0094 peptidase C26 K07010 K07010; putative glutamine amidotransferase
B Family C27
B Family C30
B Family C37
B Family C39
B Family C40
C A2cp1_0772 conserved hypothetical protein K13695 nlpC; probable lipoprotein NlpC
B Family C44
C A2cp1_4361 amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
C A2cp1_0869 Glutamate synthase (ferredoxin) K00265 gltB; glutamate synthase (NADPH) large chain [EC:1.4.1.13]
C A2cp1_4102 glucosamine/fructose-6-phosphate aminotransferase, isomerizing K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
C A2cp1_2956 asparagine synthase (glutamine-hydrolyzing) K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]
C A2cp1_2970 asparagine synthase K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]
B Family C45
B Family C46: hedgehog family
B Family C47: staphopain family
B Family C48: Ulp1 endopeptidase family
B Family C50: separase family
B Family C54: Aut2 peptidase family
B Family C55: YopJ protease family
B Family C56: PfpI endopeptidase family
C A2cp1_3240 intracellular protease, PfpI family K05520 yhbO; deglycase [EC:3.5.1.124]
B Family C57: vaccinia virus I7 peptidase family
B Family C58
B Family C59
B Family C60
B Family C63
B Family C64
B Family C65
B Family C67
B Family C69
C A2cp1_3966 peptidase U34 dipeptidase K08659 pepDA; dipeptidase [EC:3.4.-.-]
B Family C70
B Family C75
B Family C76
B Family C78
B Family C79
B Family C82
C A2cp1_3103 ErfK/YbiS/YcfS/YnhG family protein K16291 erfK; L,D-transpeptidase ErfK/SrfK
C A2cp1_1662 ErfK/YbiS/YcfS/YnhG family protein K16291 erfK; L,D-transpeptidase ErfK/SrfK
B Family C83
B Family C85
B Family C86
B Family C88
B Family C89
B Family C97
B Family C98
B Family C110
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AGlutamic peptidases
B Family G1
B Family G4
B Family G5: prenyl protease 2 family
C A2cp1_1586 Abortive infection protein K07052 K07052; CAAX protease family protein
C A2cp1_3224 Abortive infection protein K07052 K07052; CAAX protease family protein
C A2cp1_1358 Abortive infection protein K07052 K07052; CAAX protease family protein
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AMetallo peptidases
B Family M1
C A2cp1_2528 Peptidase M1 membrane alanine aminopeptidase K08776 NPEPPS; puromycin-sensitive aminopeptidase [EC:3.4.11.14]
B Family M2
C A2cp1_1939 Peptidyl-dipeptidase A K01283 ACE; peptidyl-dipeptidase A [EC:3.4.15.1]
B Family M3
C A2cp1_3302 Peptidyl-dipeptidase Dcp K01284 dcp; peptidyl-dipeptidase Dcp [EC:3.4.15.5]
C A2cp1_1902 oligoendopeptidase F K08602 pepF; oligoendopeptidase F [EC:3.4.24.-]
B Family M4: thermolysin family
B Family M5: mycolysin family
B Family M6: immune inhibitor A family
C A2cp1_0344 M6 family metalloprotease domain protein K09607 ina; immune inhibitor A [EC:3.4.24.-]
B Family M7: snapalysin family
B Family M8: leishmanolysin family
B Family M9
B Family M10
B Family M12: astacin/adamalysin family
B Family M13: neprilysin family
C A2cp1_1270 Endothelin-converting enzyme 1 K07386 pepO; putative endopeptidase [EC:3.4.24.-]
B Family M14: carboxypeptidase A family
B Family M15: zinc D-Ala-D-Ala carboxypeptidase family
B Family M16: pitrilysin family
C A2cp1_1427 peptidase M16 domain protein K07263 pqqL; zinc protease [EC:3.4.24.-]
C A2cp1_2079 peptidase M16 domain protein K07263 pqqL; zinc protease [EC:3.4.24.-]
C A2cp1_2078 peptidase M16 domain protein K07263 pqqL; zinc protease [EC:3.4.24.-]
C A2cp1_3528 peptidase M16 domain protein K07263 pqqL; zinc protease [EC:3.4.24.-]
C A2cp1_0320 peptidase M16 domain protein K07263 pqqL; zinc protease [EC:3.4.24.-]
C A2cp1_0406 peptidase M16 domain protein K07263 pqqL; zinc protease [EC:3.4.24.-]
C A2cp1_0120 peptidase M16 domain protein K07263 pqqL; zinc protease [EC:3.4.24.-]
C A2cp1_0121 peptidase M16 domain protein K07263 pqqL; zinc protease [EC:3.4.24.-]
B Family M17: leucyl aminopeptidase family
C A2cp1_4247 Leucyl aminopeptidase K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1]
B Family M18
B Family M19: membrane dipeptidase family
C A2cp1_3959 Membrane dipeptidase K01273 DPEP; membrane dipeptidase [EC:3.4.13.19]
B Family M20
C A2cp1_0190 peptidase dimerisation domain protein K01295 cpg; glutamate carboxypeptidase [EC:3.4.17.11]
C A2cp1_3969 peptidase M20 K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18]
C A2cp1_1877 aminoacyl-histidine dipeptidase K01270 pepD; dipeptidase D [EC:3.4.13.-]
B Family M23
C A2cp1_3812 Peptidase M23 K19304 mepM; murein DD-endopeptidase [EC:3.4.24.-]
B Family M24
C A2cp1_2040 methionine aminopeptidase, type I K01265 map; methionyl aminopeptidase [EC:3.4.11.18]
C A2cp1_2548 methionine aminopeptidase, type I K01265 map; methionyl aminopeptidase [EC:3.4.11.18]
C A2cp1_2188 methionine aminopeptidase, type I K01265 map; methionyl aminopeptidase [EC:3.4.11.18]
C A2cp1_2485 methionine aminopeptidase, type I K01265 map; methionyl aminopeptidase [EC:3.4.11.18]
C A2cp1_3406 peptidase M24 K01262 pepP; Xaa-Pro aminopeptidase [EC:3.4.11.9]
B Family M26
B Family M27
B Family M28: aminopeptidase Y family
B Family M29: aminopeptidase T family
B Family M32: carboxypeptidase Taq family
B Family M34: anthrax lethal factor family
B Family M35: deuterolysin family
B Family M36: fungalysin family
C A2cp1_3130 peptidase M36 fungalysin K01417 MEP; extracellular elastinolytic metalloproteinase [EC:3.4.24.-]
B Family M38: beta-aspartyl dipeptidase family
B Family M41: FtsH endopeptidase family
C A2cp1_2460 ATP-dependent metalloprotease FtsH K03798 ftsH; cell division protease FtsH [EC:3.4.24.-]
C A2cp1_2158 ATP-dependent metalloprotease FtsH K03798 ftsH; cell division protease FtsH [EC:3.4.24.-]
C A2cp1_4397 ATP-dependent metalloprotease FtsH K03798 ftsH; cell division protease FtsH [EC:3.4.24.-]
B Family M42: glutamyl aminopeptidase family
B Family M43: cytophagalysin family
B Family M44
B Family M48: Ste24 endopeptidase family
C A2cp1_1607 Ste24 endopeptidase K06013 STE24; STE24 endopeptidase [EC:3.4.24.84]
C A2cp1_1945 peptidase M48 Ste24p K03799 htpX; heat shock protein HtpX [EC:3.4.24.-]
C A2cp1_3025 peptidase M48 Ste24p K03799 htpX; heat shock protein HtpX [EC:3.4.24.-]
B Family M49: dipeptidyl-peptidase III family
B Family M50: S2P protease family
C A2cp1_1249 membrane-associated zinc metalloprotease K11749 rseP; regulator of sigma E protease [EC:3.4.24.-]
C A2cp1_3722 membrane-associated zinc metalloprotease K11749 rseP; regulator of sigma E protease [EC:3.4.24.-]
B Family M54
C A2cp1_0006 peptidase zinc-dependent K06974 amzA; archaemetzincin [EC:3.4.-.-]
C A2cp1_1953 peptidase zinc-dependent K06974 amzA; archaemetzincin [EC:3.4.-.-]
C A2cp1_3039 conserved hypothetical protein K06974 amzA; archaemetzincin [EC:3.4.-.-]
B Family M55: DppA aminopeptidase family
B Family M56
B Family M67
B Family M72
B Family M73
B Family M74
B Family M80
B Family M82
B Family M85
B Family M88
B Family M90
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AAsparagine peptide lyases
B Family N1
B Family N8
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AMixed peptidases
B Family P1: DmpA aminopeptidase family
C A2cp1_1507 peptidase S58 DmpA K01266 dmpA; D-aminopeptidase [EC:3.4.11.19]
B Family P2
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ASerine peptidases
B Family S1: chymotrypsin family
C A2cp1_2161 protease Do K04771 degP; serine protease Do [EC:3.4.21.107]
C A2cp1_1243 2-alkenal reductase K04771 degP; serine protease Do [EC:3.4.21.107]
C A2cp1_0415 peptidase S1 and S6 chymotrypsin/Hap K04771 degP; serine protease Do [EC:3.4.21.107]
B Family S3: togavirin family
B Family S6
B Family S7: flavivirin family
B Family S8: subtilisin family
C A2cp1_0256 peptidase S8 and S53 subtilisin kexin sedolisin K14645 K14645; serine protease [EC:3.4.21.-]
B Family S9: prolyl oligopeptidase family
C A2cp1_2619 peptidase S9 prolyl oligopeptidase active site domain protein K01278 DPP4; dipeptidyl-peptidase 4 [EC:3.4.14.5]
B Family S10
B Family S11: D-Ala-D-Ala carboxypeptidase A family
B Family S12: D-Ala-D-Ala carboxypeptidase B family
B Family S13: D-Ala-D-Ala peptidase C family
C A2cp1_3950 D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase K07259 dacB; serine-type D-Ala-D-Ala carboxypeptidase/endopeptidase (penicillin-binding protein 4) [EC:3.4.16.4 3.4.21.-]
B Family S14: ClpP endopeptidase family
C A2cp1_3499 ATP-dependent Clp protease, proteolytic subunit ClpP K01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92]
C A2cp1_1304 peptidase S14 ClpP K01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92]
B Family S15
B Family S16: lon protease family
C A2cp1_2231 ATP-dependent protease La K01338 lon; ATP-dependent Lon protease [EC:3.4.21.53]
C A2cp1_3496 ATP-dependent protease La K01338 lon; ATP-dependent Lon protease [EC:3.4.21.53]
B Family S21: assemblin family
B Family S24: LexA family
C A2cp1_2238 SOS-response transcriptional repressor, LexA K01356 lexA; repressor LexA [EC:3.4.21.88]
B Family S26: signal peptidase I family
C A2cp1_2333 signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89]
C A2cp1_4311 signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89]
B Family S28
B Family S31
B Family S32
B Family S33
B Family S41: C-terminal processing peptidase family
C A2cp1_0704 carboxyl-terminal protease K03797 E3.4.21.102; carboxyl-terminal processing protease [EC:3.4.21.102]
C A2cp1_3939 carboxyl-terminal protease K03797 E3.4.21.102; carboxyl-terminal processing protease [EC:3.4.21.102]
B Family S45
C A2cp1_4037 peptidase S45 penicillin amidase K01434 pac; penicillin G amidase [EC:3.5.1.11]
B Family S49: protease IV family
C A2cp1_1267 signal peptide peptidase SppA, 36K type K04773 sppA; protease IV [EC:3.4.21.-]
C A2cp1_2434 signal peptide peptidase SppA, 36K type K04773 sppA; protease IV [EC:3.4.21.-]
B Family S50
B Family S51
B Family S53
B Family S54: Rhomboid family
C A2cp1_1012 Rhomboid family protein K07059 K07059; rhomboid family protein
B Family S55: SpoIVB peptidase family
B Family S62
B Family S66
C A2cp1_3542 peptidase U61 LD-carboxypeptidase A K01297 ldcA; muramoyltetrapeptide carboxypeptidase [EC:3.4.17.13]
B Family S77: phage prohead processing peptidase family
B Family S78
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AThreonine peptidases
B Family T1: proteasome family
C A2cp1_2880 20S proteasome A and B subunits K01419 hslV; ATP-dependent HslUV protease, peptidase subunit HslV [EC:3.4.25.2]
B Family T2
C A2cp1_1593 Asparaginase K13051 ASRGL1; L-asparaginase / beta-aspartyl-peptidase [EC:3.5.1.1 3.4.19.5]
B Family T3: gamma-glutamyltransferase family
C A2cp1_4100 gamma-glutamyltransferase K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
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APeptidases of unknown catalytic type
B Family U32
B Family U62
C A2cp1_3986 peptidase U62 modulator of DNA gyrase K03592 pmbA; PmbA protein
C A2cp1_3987 peptidase U62 modulator of DNA gyrase K03568 tldD; TldD protein
C A2cp1_1479 peptidase U62 modulator of DNA gyrase K03568 tldD; TldD protein
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APeptidase inhibitors
B Family I1: Kazal family
B Family I2: Kunitz - BPTI family
B Family I4: serpin family
B Family I11: ecotin family
B Family I17: WAP-type family
B Family I25: cystatin family
B Family I27: calpastatin family
B Family I32: IAP family
B Family I34: IA3 family
B Family I35: timp family
B Family I39: alpha2M family
C A2cp1_1926 alpha-2-macroglobulin domain protein K06894 yfhM; alpha-2-macroglobulin
B Family I47: latexin family
B Family I49: proSAAS family
B Family I51: IC family
B Family I57: staphostatin B family
B Family I63
B Family I80
B Family I87
C A2cp1_3679 HflC protein K04087 hflC; modulator of FtsH protease HflC
C A2cp1_3678 HflK protein K04088 hflK; modulator of FtsH protease HflK
B Family I93
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: December 13, 2023
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Classification taken and modified from MEROPS