+F Repair protein KO
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DNA Repair and Recombination Proteins - Acetobacterium woodii
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D Awo_c04550 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase Ogt K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E Awo_c28800 ung; uracil-DNA glycosylase Ung K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E Awo_c06360 mutY; A/G-specific adenine glycosylase MutY K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E Awo_c21960 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
E Awo_c15090 ATP-dependent DNA helicase K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D Awo_c14430 dut1; deoxyuridine 5'-triphosphate nucleotidohydrolase Dut1 K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D Awo_c19520 dut2; deoxyuridine 5'-triphosphate nucleotidohydrolase Dut2 K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D Awo_c04550 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase Ogt K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E Awo_c28800 ung; uracil-DNA glycosylase Ung K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E Awo_c06360 mutY; A/G-specific adenine glycosylase MutY K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E Awo_c31660 fpg; formamidopyrimidine-DNA glycosylase Fpg K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E Awo_c21960 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E Awo_c08490 xth; exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E Awo_c08380 nfo; apurinic endonuclease Apn1 K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
D RecJ
E Awo_c21810 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E Awo_c02970 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E Awo_c25330 uvrA1; excinuclease ABC, subunit A K03701 uvrA; excinuclease ABC subunit A
E Awo_c25340 uvrB; excinuclease ABC, subunit B K03702 uvrB; excinuclease ABC subunit B
E Awo_c29190 putative excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C
E Awo_c25280 uvrC; excinuclease ABC, subunit C K03703 uvrC; excinuclease ABC subunit C
E Awo_c18030 pcrA3; ATP-dependent DNA helicase PcrA3 K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E Awo_c02960 pcrA1; ATP-dependent DNA helicase PcrA1 K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E Awo_c06290 pcrA2; ATP-dependent DNA helicase PcrA2 K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E Awo_c18190 pcrA4; ATP-dependent DNA helicase PcrA4 K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E Awo_c02970 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F Awo_c09100 rpoB; DNA-directed RNA polymerase beta subunit RpoB K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F Awo_c09110 rpoC; DNA-directed RNA polymerase beta' subunit RpoC K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F Awo_c28360 rpoA; DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F Awo_c21640 rpoZ; DNA-directed RNA polymerase omega chain K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F Awo_c29980 mfd; transcription-repair coupling factor Mfd K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E Awo_c16920 mutS1; DNA mismatch repair protein MutS1 K03555 mutS; DNA mismatch repair protein MutS
E Awo_c12920 MutS-like protein K07456 mutS2; DNA mismatch repair protein MutS2
D Molecular matchmaker
E Awo_c22110 mutL; DNA mismatch repair protein MutL K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
D DNA exonucleases
E Awo_c13130 xseA; exodeoxyribonuclease VII large subunit XseA K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E Awo_c13140 xseB; exodeoxyribonuclease VII small subunit XseB K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E Awo_c12780 dnaE; DNA polymerase III, alpha subunit DnaE K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E Awo_c25450 polC2; DNA polymerase III K03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7]
E Awo_c00020 dnaN; DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E Awo_c16600 holA; DNA polymerase III, delta subunit HolA K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E Awo_c35390 dnaX2; DNA polymerase III gamma/tau subunit DnaX2 K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E Awo_c17820 polC1; DNA polymerase III PolC1 K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E Awo_c25730 dnaX1; DNA polymerase III gamma/tau subunit DnaX1 K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E Awo_c02970 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E Awo_c18030 pcrA3; ATP-dependent DNA helicase PcrA3 K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E Awo_c02960 pcrA1; ATP-dependent DNA helicase PcrA1 K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E Awo_c06290 pcrA2; ATP-dependent DNA helicase PcrA2 K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E Awo_c18190 pcrA4; ATP-dependent DNA helicase PcrA4 K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E Awo_c35500 ssb2; single-strand binding protein Ssb2 K03111 ssb; single-strand DNA-binding protein
E Awo_c11270 ssb1; single-strand binding protein Ssb1 K03111 ssb; single-strand DNA-binding protein
E Awo_c34920 N6 adenine-specific DNA methylase, D12 class K06223 dam; DNA adenine methylase [EC:2.1.1.72]
E Awo_c30860 putative DNA methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
E Awo_c35180 phage-like N6 adenine-specific DNA methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
E Awo_c06500 vsr; DNA mismatch endonuclease Vsr K07458 vsr; DNA mismatch endonuclease, patch repair protein [EC:3.1.-.-]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E Awo_c26960 helicase, RecD/TraA family K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E Awo_c19560 recA; recombinase A K03553 recA; recombination protein RecA
E Awo_c13000 ruvA; holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E Awo_c13010 ruvB; holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E Awo_c21630 priA; primosomal protein N PriA K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E Awo_c10110 sbcC; exonuclease SbcC K03546 sbcC; DNA repair protein SbcC/Rad50
E Awo_c27080 mppE; putative metallophosphoesterase MppE K03547 sbcD; DNA repair protein SbcD/Mre11
E Awo_c10100 sbcD; DNA repair exonuclease subunit D K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E Awo_c19560 recA; recombinase A K03553 recA; recombination protein RecA
E Awo_c12990 radA; DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
E Awo_c00040 recF; DNA replication and repair protein RecF K03629 recF; DNA replication and repair protein RecF
E Awo_c04740 transcriptional regulator K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E Awo_c21510 recG; ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E Awo_c21810 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E Awo_c19290 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E Awo_c25720 recR; recombination protein RecR K06187 recR; recombination protein RecR
E Awo_c13190 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
E Awo_c11030 recU; holliday junction-specific endonuclease RecU K03700 recU; recombination protein U
E Awo_c13000 ruvA; holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E Awo_c13010 ruvB; holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
D AddAB pathway proteins
E Awo_c25590 addA; ATP-dependent helicase/nuclease subunit A K16898 addA; ATP-dependent helicase/nuclease subunit A [EC:5.6.2.4 3.1.-.-]
E Awo_c25600 addB; ATP-dependent helicase/deoxyribonuclease subunit B K16899 addB; ATP-dependent helicase/nuclease subunit B [EC:5.6.2.4 3.1.-.-]
D Other HR factor
E Awo_c29290 cas1; CRISPR-associated endonuclease Cas1 K15342 cas1; CRISP-associated protein Cas1
D Archaeal homologous recombinant proteins
E Awo_c10110 sbcC; exonuclease SbcC K03546 sbcC; DNA repair protein SbcC/Rad50
E Awo_c27080 mppE; putative metallophosphoesterase MppE K03547 sbcD; DNA repair protein SbcD/Mre11
E Awo_c10100 sbcD; DNA repair exonuclease subunit D K03547 sbcD; DNA repair protein SbcD/Mre11
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F Awo_c00060 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F Awo_c00050 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F Awo_c19360 topA; DNA topoisomerase II K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F Awo_c29940 hup; DNA-binding protein HU K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F Awo_c21810 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F Awo_c19290 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F Awo_c25720 recR; recombination protein RecR K06187 recR; recombination protein RecR
F Awo_c02970 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
E Supressor
F Awo_c20520 recQ; ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F Awo_c25330 uvrA1; excinuclease ABC, subunit A K03701 uvrA; excinuclease ABC subunit A
F Awo_c25340 uvrB; excinuclease ABC, subunit B K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D Awo_c11630 dinB1; DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D Awo_c15060 dinB3; DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D Awo_c16980 UV inducible DNA polymerase impB/mucB/samB family K03502 umuC; DNA polymerase V
C Other SOS response factors
D Awo_c19560 recA; recombinase A K03553 recA; recombination protein RecA
D Awo_c19820 lexA; SOS-response transcriptional repressor K01356 lexA; repressor LexA [EC:3.4.21.88]
D Awo_c13190 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D Awo_c35500 ssb2; single-strand binding protein Ssb2 K03111 ssb; single-strand DNA-binding protein
D Awo_c11270 ssb1; single-strand binding protein Ssb1 K03111 ssb; single-strand DNA-binding protein
D Awo_c26380 recX; regulatory protein RecX K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
C Modulation of nucleotide pools
D Awo_c14430 dut1; deoxyuridine 5'-triphosphate nucleotidohydrolase Dut1 K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D Awo_c19520 dut2; deoxyuridine 5'-triphosphate nucleotidohydrolase Dut2 K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D Awo_c19660 nrdJ; vitamin B12-dependent ribonucleotide reductase large subunit NrdJ K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
C Others
D Awo_c19470 putative hydrolase K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024