+D	Messenger RNA Biogenesis	KO
#<h2><a href="/kegg/brite.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; Prokaryotic Defense System - Paraburkholderia fungorum</h2>
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A<b>CRISPR-Cas system</b>
B  Universal Cas proteins
B  Type I CRISPR-Cas system
C    Type I signiture cas proteins
C    Subtype I-A factors
C    Subtype I-B factors
C    Subtype I-C factors
C    Subtype I-D factors
C    Subtype I-E factors
C    Subtype I-F factors
C    Subtype I-U factors
B  Type II CRISPR-Cas system
C    Type II signiture cas proteins
C    Subtype II-A factors
C    Subtype II-B factors
B  Type III CRISPR-Cas system
C    Type III signiture cas proteins
C    Subtype III-A factors
C    Subtype III-B factors
C    Subtype III-U factors
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A<b>Restriction and modification system (R-M system)</b>
B  Type I R-M system
B  Type II R-M system
C    Restriction endonucleases
D      OI25_7843 putative type II restriction enzyme	K01155 E3.1.21.4; type II restriction enzyme [EC:3.1.21.4] 
C    DNA methyltransferases
D      OI25_5297 DNA methylase family protein	K00571 E2.1.1.72; site-specific DNA-methyltransferase (adenine-specific) [EC:2.1.1.72] 
D      OI25_625 dcm; DNA (cytosine-5-)-methyltransferase family protein	K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] 
B  Type III R-M system
B  Type IV R-M system
C    OI25_591 restriction endonuclease family protein	K07448 mrr; restriction system protein 
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A<b>Toxin-antitoxin system (TA system)</b>
B  Type I TA system
C    Hok-Sok
C    SymE-SymR
C    Ldr-Rdl
C    TisB-IstR
C    Ibs-Sib
C    ShoB-OhsC
C    RalR-RalA
B  Type II TA system
C    MazF-MazE
D      OI25_7407 pemK-like family protein	K07171 mazF; mRNA interferase MazF [EC:3.1.-.-] 
D      OI25_7408 antidote-toxin recognition MazE family protein	K07172 mazE; antitoxin MazE 
C    ChpB-ChpS
C    YhaV-PrlF
C    RelE/StbE-RelB/StbD
D      OI25_7867 hypothetical protein	K18918 relB; RHH-type transcriptional regulator, rel operon repressor / antitoxin RelB 
C    YafQ-dinJ
C    YoeB-YefM
C    HipA-HipB
D      OI25_4494 hypothetical protein	K07154 hipA; serine/threonine-protein kinase HipA [EC:2.7.11.1] 
D      OI25_4202 hypothetical protein	K07154 hipA; serine/threonine-protein kinase HipA [EC:2.7.11.1] 
D      OI25_3518 hypothetical protein	K07154 hipA; serine/threonine-protein kinase HipA [EC:2.7.11.1] 
D      OI25_5338 helix-turn-helix family protein	K15773 hipB; HTH-type transcriptional regulator / antitoxin HipB 
D      OI25_4201 helix-turn-helix family protein	K15773 hipB; HTH-type transcriptional regulator / antitoxin HipB 
C    HicA-HicB
C    YafO-YafN
C    Hha-TomB
C    PspC-PspB
C    CcdB-CcdA
C    ParE-ParD
C    Doc-Phd
C    HigB-HigA
D      OI25_620 hypothetical protein	K19166 higB; mRNA interferase HigB [EC:3.1.-.-] 
D      OI25_7210 hypothetical protein	K19166 higB; mRNA interferase HigB [EC:3.1.-.-] 
D      OI25_2357 plasmid maintenance system killer family protein	K07334 higB-1; toxin HigB-1 
D      OI25_619 hypothetical protein	K18831 higA; HTH-type transcriptional regulator / antitoxin HigA 
D      OI25_7211 putative dNA-binding transcriptional regulator	K18831 higA; HTH-type transcriptional regulator / antitoxin HigA 
D      OI25_3820 putative hTH-type transcriptional regulator,YgjM-like protein	K18831 higA; HTH-type transcriptional regulator / antitoxin HigA 
D      OI25_2356 higA; addiction module antidote protein, HigA family	K21498 higA-1; antitoxin HigA-1 
C    MqsR-MqsA
D      OI25_4097 mqsR; mRNA interferase MqsR	K13651 mqsR; motility quorum-sensing regulator / GCU-specific mRNA interferase toxin 
D      OI25_4096 mqsA; antitoxin MqsA	K13655 mqsA; HTH-type transcriptional regulator / antitoxin MqsA 
C    VapC-VapB
C    PezT-PezA
C    YobL-YobK
C    YokI-YokJ
C    YqcG-YqcF
C    YxiD-YxxD
C    FitB-FitA
C    BC_0920-BC_0921
C    Type II TA system related factors
D      OI25_1951 ftsZ; cell division protein FtsZ	K03531 ftsZ; cell division protein FtsZ 
D      OI25_6898 cell shape determining, MreB/Mrl family protein	K03569 mreB; rod shape-determining protein MreB and related proteins 
D      OI25_7074 cell shape determining, MreB/Mrl family protein	K03569 mreB; rod shape-determining protein MreB and related proteins 
D      OI25_1369 cell shape determining, MreB/Mrl family protein	K03569 mreB; rod shape-determining protein MreB and related proteins 
D      OI25_552 parC; DNA topoisomerase IV, A subunit	K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2] 
D      OI25_553 DNA gyrase B subunit, carboxyl terminus family protein	K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2] 
D      OI25_3099 gltX; glutamate--tRNA ligase	K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] 
B  Type III TA system
C    AbiQ system
B  Type IV TA system
C    YeeV-YeeU
C    CptA-CptB
D      OI25_5308 flavinator of succinate dehydrogenase family protein	K09159 cptB; antitoxin CptB 
B  Type V TA system
C    GhoT-GhoS
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A<b>DNA phosphothiolation system</b>
B  Sulfur modification proteins
C    OI25_2852 iscS; cysteine desulfurase IscS	K04487 iscS; cysteine desulfurase [EC:2.8.1.7] 
C    OI25_7197 phosphoadenosine phosphosulfate reductase family protein	K19170 dndC; DNA sulfur modification protein DndC 
B  DNA phosphorothioation-dependent restriction proteins
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#Last updated: November 7, 2023