+D
#
Transporters - Cryptosporidium hominis
%
!
AABC transporters, eukaryotic type
B ABCA (ABC1) subfamily
C ABCA1, 2, 3, 4, 7, 12, 13 subgroups
C ABCA5, 6, 8, 9, 10 subgroups
B ABCB (MDR/TAP) subfamily
C ABCB2, 3, 8, 9, 10 subgroups
C ABCB1, 4, 5 subgroups
D Chro.60540 ATP-binding cassette protein 3 K05658 ABCB1; ATP-binding cassette, subfamily B (MDR/TAP), member 1 [EC:7.6.2.2]
C ABCB6, 7 subgroups
D Chro.10157 ABC transporter (1D44) K05662 ABCB7; ATP-binding cassette, subfamily B (MDR/TAP), member 7
C ABCB11 subgroup
C ABCB-BAC subgroup
B ABCC (CFTR/MRP) subfamily
C ABCC1, 2, 3, 4, 5, 6, 10, 11, 12, 13 subgroups
D Chro.40158 ATP-binding cassette protein 1 K05665 ABCC1; ATP-binding cassette, subfamily C (CFTR/MRP), member 1 [EC:7.6.2.3]
D Chro.40156 hypothetical protein K05665 ABCC1; ATP-binding cassette, subfamily C (CFTR/MRP), member 1 [EC:7.6.2.3]
C ABCC7 subgroup
C ABCC8, 9 subgroups
C ABCC-BAC subgroup
B ABCD (ALD) subfamily
C ABCD1 subgroup
C ABCD2 subgroup
C ABCD3 subgroup
C ABCD4 subgroup
C Others
B ABCG (White) subfamily
C ABCG1, 4 subgroups
D Chro.60617 ABC transporter protein K05679 ABCG1; ATP-binding cassette, subfamily G (WHITE), member 1
C ABCG2, 3 subgroups
D Chro.60627 ABC transporter protein K05681 ABCG2; ATP-binding cassette, subfamily G (WHITE), member 2
C ABCG5, 8 subgroups
B Other subfamilies
C Macrolide exporter
C Other ABC transporters
#
AABC transporters, prokaryotic type
B Mineral and organic ion transporters
C Sulfate/thiosulfate transporter
C Molybdate transporter
C Molybdate/tungstate transporter
C Tungstate transporter
C Nitrate/nitrite transporter
C Bicarbonate transporter
C Taurine transporter
C Sulfonate transporter
C Phthalate transporter
C Iron(III) transporter
C Thiamine transporter
C Spermidine/putrescine transporter
C Putrescine transporter
C Putative spermidine/putrescine transporter
C Mannopine transporter
C 2-Aminoethylphosphonate transporter
C Glycine betaine/proline transporter
C Osmoprotectant transporter
C Riboflavin transporter
C Putative hydroxymethylpyrimidine transporter
C Putative thiamine transporter
C Putative thiamine transporter
C NitT/TauT family transporter
B Saccharide, polyol, and lipid transporters
C Maltose/maltodextrin transporter
C Maltose transporter
C Arabinogalactan oligomer/maltooligosaccharide transport system
C Raffinose/stachyose/melibiose transporter
C Alpha-glucoside transporter
C Glucose/arabinose transporter
C Glucose/mannose transporter
C Trehalose/maltose transporter
C Trehalose transporter
C N-Acetylglucosamine transporter
C Cellobiose transporter
C N,N'-Diacetylchitobiose transporter
C Putative chitobiose transporter
C L-Arabinose transporter
C Lactose/L-arabinose transporter
C L-Arabinose/D-xylose transporter
C Oligogalacturonide transporter
C Alpha-1,4-digalacturonate transporter
C Putative aldouronate transporter
C Alpha-galactoside transporter
C Methyl-galactoside transporter
C D-Galactose transporter
C D-Xylose transporter
C Xylobiose transporter
C Fucose transporter
C Sugar transporter
C Multiple sugar transporter
C D-Allose transporter
C Fructose transporter
C Rhamnose transporter
C Ribose transporter
C Galactofuranose transporter
C Erythritol transporter
C Putative xylitol transporter
C Inositol transporter
C Inositol transporter
C Inositol-phosphate transporter
C Fructooligosaccharide transporter
C Fructooligosaccharide transporter
C Glycerol transporter
C Putative sn-Glycerol 3-phosphate transporter
C Putative sorbitol/mannitol transporter
C Arabinooligosaccharide transporter
C Arabinooligosaccharide transporter
C Polygalacturonan/rhamnogalacturonan transporter
C Pectin-derived oligosaccharide transporter
C General nucleoside transporter
C Riboflavin transporter
C UDP-glucose/iron transporter
C AI-2 transporter
C gamma-Hexachlorocyclohexane transporter
C Phospholipid transporter
C Mce system transporter
C Putative multiple sugar transporter
C Putative simple sugar transporter
B Phosphate and amino acid transporters
C Phosphate transporter
C Phosphonate transporter
C Lysine/arginine/ornithine transporter
C Histidine transporter
C Glutamine transporter
C Arginine transporter
C Glutamate/aspartate transporter
C Aspartate/glutamate/glutamine transporter
C Octopine/nopaline transporter
C General L-amino acid transporter
C Glutamate transporter
C Cystine transporter
C L-Cystine transporter
C Arginine/ornithine transporter
C Arginine/lysine/histidine/glutamine transporter
C Arginine/lysine/histidine transporter
C Hydroxyproline transporter
C Branched-chain amino acid transporter
C Neutral amino acid transporter
C D-Methionine transporter
C Urea transporter
C Putative tryptophan/tyrosine transporter
C Putative lysine transporter
C Putative lysine/arginine/ornithine/histidine/octopine transporter
C Putative S-methylcysteine transporter
C Putative polar amino acid transporter
B Peptide and nickel transporters
C Oligopeptide transporter
C Dipeptide transporter
C Dipeptide transporter
C Cationic peptide transporter
C Nickel transporter
C Nickel transporter
C Glutathione transporter
C Peptides/nickel transporter
C Microcin C transporter
B Metallic cation, iron-siderophore and vitamin B12 transporters
C Ferric citrate transporter
C Ferric hydroxamate transporter
C Ferric hydroxamate/heme transporter
C Heme transporter
C Heme transporter
C Iron-siderophore transporter
C Iron-siderophore transporter
C Iron-siderophore transporter
C Iron complex transporter
C Vitamin B12 transporter
C Cobalamin transporter
C Manganese transporter
C Manganese transporter
C Zinc transporter
C Iron/zinc/manganese/copper transporter
C Manganese/iron transporter
C Manganese/zinc transporter
C Manganese/zinc/iron transporter
C Manganese/iron transporter
C Cobalt transporter
C Nickel transporter
C Biotin transporter
C Energy-coupling factor transporter
C Putative zinc/manganese transporter
B ABC-2 type and other transporters
C Multidrug/hemolysin transporter
C Capsular polysaccharide transporter
C Vi polysaccharide transporter
C Homopolymeric O-antigen
C Lipopolysaccharide transporter
C Teichoic acid transporter
C Lipooligosaccharide transporter
C Sodium transporter
C Lantibiotic transporter
C Lantibiotic transporter
C Copper-processing transporter
C Gliding motility-associated transporter
C Putative peptide transporter
C Hemin transporter
C Daunorubicin/doxorubicin transporter
C Oleandomycin transporter
C Pyoluteorin transporter
C Drug efflux transporter
C Linearmycin/streptolysin S transporer
C Bacitracin transporter
C Bacitracin transporter
C Bacitracin transporter
C Beta-exotoxin I transporter
C Polyether ionophore transporter
C Uncharacterized ABC transporter
C Cationic antimicrobial peptide transporter
C Fluoroquinolones transporter
C Lipoprotein-releasing transporter
C Acetoin utilization transporter
C Antimicrobial peptide resistance transporter
C Heterocyst specific transporter
C Heme transporter
C Cell division transporter
C Viologen exporter family transporter
C ABC-2 type transporter
C ABC-2 type transporter
C Putative ABC transporter
C Orphan ABC ATPase
#
ASolute carrier family (SLC)
B SLC1: High-affinity glutamate and neutral amino acid transporter
B SLC2: Facilitative GLUT transporter
B SLC3: Heavy subunits of the heteromeric amino acid transporters
B SLC4: Bicarbonate transporter
B SLC5: Sodium glucose cotransporter
B SLC6: Sodium- and chloride-dependent neurotransmitter transporter
B SLC7: Cationic amino acid transporter/glycoprotein-associated
B SLC8: Na+/Ca2+ exchanger
B SLC9: Na+/H+ exchanger
C Chro.60024 Na+/H+ antiporter K14726 SLC9A10_11; solute carrier family 9 (sodium/hydrogen exchanger), member 10/11
C Chro.60025 Na+/H+ antiporter K14726 SLC9A10_11; solute carrier family 9 (sodium/hydrogen exchanger), member 10/11
B SLC10: Sodium bile salt cotransporter
B SLC11: Proton-coupled metal ion transporter
B SLC12: Electroneutral cation-coupled Cl cotransporter
B SLC13: Human Na+-sulfate/carboxylate cotransporter
B SLC14: Urea transporter
B SLC15: Proton oligopeptide cotransporter
B SLC16: Monocarboxylate transporter
B SLC17: Vesicular glutamate transporter
B SLC18: Vesicular amine transporter
B SLC19: Folate/thiamine transporter
B SLC20: Type III Na+-phosphate cotransporter
B SLC21/ASLCO: Organic anion transporter
B SLC22: Organic cation/anion/zwitterion transporter
B SLC23: Na+-dependent ascorbic acid transporter
B SLC24: Na+/(Ca2+-K+) exchanger
C Chro.30397 cation exchanger (CAX11) K13754 SLC24A6; solute carrier family 24 (sodium/potassium/calcium exchanger), member 6
B SLC25: Mitochondrial carrier
C Chro.20060 PfMPC K15102 SLC25A3; solute carrier family 25 (mitochondrial phosphate transporter), member 3
C Chro.80141 ADP/ATP carrier K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
C Chro.10071 oxoglutarate/malate translocator protein K15104 SLC25A11; solute carrier family 25 (mitochondrial oxoglutarate transporter), member 11
C Chro.60274 mitochondrial carrier protein K15111 SLC25A26; solute carrier family 25 (mitochondrial S-adenosylmethionine transporter), member 26
C Chro.20115 mitochondrial carrier protein K15113 SLC25A28_37; solute carrier family 25 (mitochondrial iron transporter), member 28/37
C Chro.10266 ENSANGP00000009305 K15115 SLC25A32; solute carrier family 25 (mitochondrial folate transporter), member 32
C Chro.60444 mitochondrial carrier K15119 SLC25A39_40; solute carrier family 25, member 39/40
B SLC26: Multifunctional anion exchanger
C Chro.70021 high affinity sulfate transporter-related K14453 K14453; solute carrier family 26, other
B SLC27: Fatty acid transporter
B SLC28: Na+-coupled nucleoside transporter
B SLC29: Facilitative nucleoside transporter
C Chro.20039 CG31911-PA K15014 SLC29A1_2_3; solute carrier family 29 (equilibrative nucleoside transporter), member 1/2/3
B SLC30: Zinc efflux transporter
C Chro.10338 zinc transporter K14689 SLC30A2; solute carrier family 30 (zinc transporter), member 2
B SLC31: Copper transporter
C Chro.10286 hypothetical protein K14686 SLC31A1; solute carrier family 31 (copper transporter), member 1
B SLC32: Vesicular inhibitory amino acid transporter
B SLC33: Acetyl-CoA transporter
B SLC34: Type II Na+-phosphate cotransporter
B SLC35: Nucleoside-sugar transporter
C Chro.20283 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter); solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member 3 K15272 SLC35A1_2_3; solute carrier family 35 (UDP-sugar transporter), member A1/2/3
C Chro.20067 nucleotide-sugar transporter (2A681) K15272 SLC35A1_2_3; solute carrier family 35 (UDP-sugar transporter), member A1/2/3
C Chro.20284 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member 3 K15272 SLC35A1_2_3; solute carrier family 35 (UDP-sugar transporter), member A1/2/3
C Chro.10013 solute carrier family 35, member 2 K15275 SLC35B1; solute carrier family 35 (UDP-galactose transporter), member B1
C Chro.80162 hypothetical protein K15279 SLC35C1; solute carrier family 35 (GDP-fucose transporter), member C1
C Chro.80171 hypothetical protein K15279 SLC35C1; solute carrier family 35 (GDP-fucose transporter), member C1
C Chro.30069 GDP-fucose transporter 1; multispan transmembrane protein fuct1 K15279 SLC35C1; solute carrier family 35 (GDP-fucose transporter), member C1
C Chro.50030 hypothetical protein K15280 SLC35C2; solute carrier family 35, member C2
B SLC36: Proton-coupled amino acid transporter
C Chro.70533 hypothetical protein K14209 SLC36A; solute carrier family 36 (proton-coupled amino acid transporter)
C Chro.30489 hypothetical protein K14209 SLC36A; solute carrier family 36 (proton-coupled amino acid transporter)
C Chro.40505 hypothetical protein K14209 SLC36A; solute carrier family 36 (proton-coupled amino acid transporter)
B SLC37: Sugar-phosphate/phosphate exchanger
C Chro.80188 hexosphosphate transport K13783 SLC37A1_2; MFS transporter, OPA family, solute carrier family 37 (glycerol-3-phosphate transporter), member 1/2
B SLC38: System A and System N sodium-coupled neutral amino acid transporter
B SLC39: Metal ion transporter
C Chro.50164 hypothetical protein K14709 SLC39A1_2_3; solute carrier family 39 (zinc transporter), member 1/2/3
C Chro.60067 transporter protein K14709 SLC39A1_2_3; solute carrier family 39 (zinc transporter), member 1/2/3
B SLC40: Basolateral iron transporter
B SLC41: MgtE-like magnesium transporter
B SLC42: Rh ammonium transporter
B SLC43: Na+-independent, system-L-like amino acid transporter
C Chro.50022 hypothetical protein K08230 SLC43A3; MFS transporter, LAT3 family, solute carrier family 43, member 3
B SLC44: Choline-like transporter
B SLC45: H+/sugar cotransporter
B SLC46: Folate transporter
B SLC47: Multidrug and Toxin Extrusion (MATE) family
B SLC48: Heme transporter
B SLC49: FLVCR-related transporter
B SLC50: Sugar efflux transporter
B SLC51: Transporter of steroid-derived molecules
B SLC52: Riboflavin transporter
B SLC54: Mitochondrial pyruvate carrier
B SLC56: Sideroflexin
B SLC57: NiPA-like magnesium transporter
C Chro.50285 hypothetical protein K22733 NIPA; magnesium transporter
B SLC58: MagT-like magnesium transporter
C Chro.80596 hypothetical protein K19478 MAGT1; dolichyl-diphosphooligosaccharide---protein glycosyltransferase subunit MAGT1/TUSC3
B SLC62: Pyrophosphate transporter
B SLC65: NPC-type cholesterol transporter
B SLC66: Lysosomal lysine-arginine transporter
#
AMajor facilitator superfamily (MFS)
B Sugar transporters
C Sugar porter (SP) family [TC:2.A.1.1]
C Oligosaccharide:H+ symporter (OHS) family [TC:2.A.1.5]
C Fucose:H+ symporter (FHS) family [TC:2.A.1.7]
C Sugar efflux transporter (SET) [TC:2.A.1.20]
C Nucleoside:H+ symporter (NHS) family [TC:2.A.1.10]
C N-Acetylglucosamine transporter (NAG-T) family [TC:2.A.1.58]
B Organic acid transporters
C Metabolite:H+ symporter (MHS) family [TC:2.A.1.6]
C Oxalate:formate antiporter (OFA) family [TC:2.A.1.11]
C Sialate:H+ symporter (SHS) family [TC:2.A.1.12]
C Monocarboxylate transporter (MCT) family [TC:2.A.1.13]
C Anion:cation symporter (ACS) family [TC:2.A.1.14]
C Aromatic acid:H+ symporter (AAHS) family [TC:2.A.1.15]
C Cyanate porter (CP) family [TC:2.A.1.17]
C Organic cation transporter (OCT) family [TC:2.A.1.19]
C Phenylproprionate permease (PPP) [TC:2.A.1.27]
C L-Amino acid transporter-3 (LAT3) family (SLC43 family) [TC:2.A.1.44]
D Chro.50022 hypothetical protein K08230 SLC43A3; MFS transporter, LAT3 family, solute carrier family 43, member 3
C Proton coupled folate transporter/heme carrier protein (PCFT/HCP) family [TC:2.A.1.50]
B Phosphate and organophosphate transporters
C Phosphate:H+ symporter (PHS) family [TC:2.A.1.9]
C Organophosphate:Pi antiporter (OPA) family [TC:2.A.1.4]
D Chro.80188 hexosphosphate transport K13783 SLC37A1_2; MFS transporter, OPA family, solute carrier family 37 (glycerol-3-phosphate transporter), member 1/2
C 1-Arseno-3-phosphoglycerate exporter (APGE) family [TC:2.A.1.83]
B Nitrate/nitrite transporters
C Nitrate/nitrite porter (NNP) family [TC:2.A.1.8]
C Proton-dependent oligopeptide transporter (POT/PTR) family [TC:2.A.17]
B Lipid transporters
C Lysophospholipid transporter (LplT) family [TC:2.A.1.42]
C Sphingosine-1-phosphate transporter (Spinster) family [TC:2.A.1.49]
B Metal transporters
C Siderophore-iron transporter (SIT) family [TC:2.A.1.16]
C Enterobactin (siderophore) exporter (EntS) family [TC:2.A.1.38]
C Nickel resistance (Nre) family [TC:2.A.1.31]
C MFS domain-containing protein family [TC:2.A.1.40]
C Putative bacteriochlorophyll delivery (BCD) family [TC:2.A.1.41]
B Protein transporters
C Vesicular neurotransmitter transporter (VNT) [TC:2.A.1.22]
C Peptide-acetyl-CoA transporter (PAT) [TC:2.A.1.25]
C Feline leukemia virus subgroup C receptor (FLVCR) [TC:2.A.1.28]
B Drug transporters
C Drug:H+ antiporter-1 (12 spanner) (DHA1) family [TC:2.A.1.2]
C Drug:H+ antiporter-2 (14 spanner) (DHA2) family [TC:2.A.1.3]
C Drug:H+ antiporter-3 (12 spanner) (DHA3) [TC:2.A.1.21]
C Putative aromatic compound/drug exporter (ACDE) family [TC:2.A.1.32]
C Fosmidomycin resistance (Fsr) family [TC:2.A.1.35]
C Acriflavin-sensitivity (YnfM) family [TC:2.A.1.36]
C Glycerophosphodiester uptake (GlpU) family [TC:2.A.1.52]
B Unknown transporters
C Unknown major facilitator-1 (UMF1) [TC:2.A.1.24]
C Unknown major facilitator-2 (UMF2) [TC:2.A.1.26]
C Putative YqgE transporter (YqgE) family [TC:2.A.1.33]
C Others
#
APhosphotransferase system (PTS)
B Enzyme I and HPr
C Enzyme I [TC:8.A.7]
C Phosphocarrier protein HPr [TC:8.A.8]
C Multiphosphoryl transfer protein
B Enzyme II [TC:4.A]
C Glucose-specific II component
C Glucose-specific II component
C N-Acetylglucosamine-specific II component
C Maltose/glucose-specific II component
C Maltose-specific II component
C D-Glucosamine-specific II component
C Sucrose-specific II component
C Beta-glucoside-specific II component
C Beta-glucoside (arbutin/salicin/cellobiose)-specific II component
C Trehalose-specific II component
C N-Acetylmuramic acid-specific II component
C Alpha-glucoside-specific II component
C Fructose-specific II component
C Fructose-specific II-like component
C Mannitol-specific II component
C 2-O-A-Mannosyl-D-glycerate-specific II component
C Lactose-specific II component
C Cellobiose-specific II component
C Glucitol/sorbitol-specific II component
C Galactitol-specific II component
C Galactose-specific II component
C Mannose-specific II component
C Mannose-specific II component
C Fructoselysine/glucoselysine-specific II component
C Fructose-specific II component
C Sorbose-specific II component
C N-Acetylgalactosamine-specific II component
C Galactosamine-specific II component
C D-Glucosaminate-specific II component
C Ascorbate-specific II component
C Nitrogen regulatory II component
C EI/HPr/EIIA hybrid protein
#
AOther transporters
B Aquaporins and small neutral solute transporters [TC:1.A.8]
C Aquaporins
C Aquaglyceroporins or glycerol-uptake facilitators
B Pores ion channels [TC:1]
C Chro.20398 hypothetical protein K00799 GST; glutathione S-transferase [EC:2.5.1.18]
C Chro.70530 hypothetical protein K00799 GST; glutathione S-transferase [EC:2.5.1.18]
C Chro.20166 hypothetical protein K16075 MRS2; magnesium transporter
C Chro.60186 dbj|baa86974.1 K21891 TMCO1; calcium load-activated calcium channel
C Chro.30153 hypothetical protein K16302 CNNM; metal transporter CNNM
C Chro.60221 CBS domain multi-pass transmembrane protein K16302 CNNM; metal transporter CNNM
C Chro.20088 hypothetical protein K07277 SAM50; outer membrane protein insertion porin family
B Electrochemical potential-driven transporters [TC:2]
C Chro.10296 calcium antiporter K07300 chaA; Ca2+:H+ antiporter
C Chro.10250 potassium/proton antiporter K26735 KEA4_5_6; K+:H+ antiporter
C Chro.70452 arsenical pump-driving ATPase K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-]
C Chro.60537 multi-pass transmembrane protein K06316 RFT1; oligosaccharide translocation protein RFT1
C Chro.70039 hypothetical protein K22736 VIT; vacuolar iron transporter family protein
C Chro.50194 hypothetical protein K17800 LETM1; LETM1 and EF-hand domain-containing protein 1, mitochondrial
C Chro.40056 CG4196-PC K23541 TMEM165; Ca2+/H+ antiporter, TMEM165/GDT1 family
B Primary active transporters [TC:3]
C Chro.10287 mitochondrial import receptor subunit tom40 K11518 TOM40; mitochondrial import receptor subunit TOM40
C Chro.60510 hypothetical protein K17780 TIM8; mitochondrial import inner membrane translocase subunit TIM8
C Chro.20443 mitochondrial import inner membrane translocase subunit tim17 K17795 TIM17; mitochondrial import inner membrane translocase subunit TIM17
C Chro.30332 mitochondrial import inner membrane translocase K17804 TIM44; mitochondrial import inner membrane translocase subunit TIM44
C Chro.80393 hypothetical protein K17496 TIM50; mitochondrial import inner membrane translocase subunit TIM50
B Transmembrane electron carriers [TC:5]
B Accessory factors involved in transport [TC:8]
B Others
C Chro.70166 hypothetical protein K17938 sbmA; peptide/bleomycin uptake transporter
C Chro.50014 sensitivity to microcin B17, possibly envelop protein K17938 sbmA; peptide/bleomycin uptake transporter
C Chro.50013 sbmA K17938 sbmA; peptide/bleomycin uptake transporter
C Chro.70165 SbmA protein K17938 sbmA; peptide/bleomycin uptake transporter
C Chro.60122 CRAL/TRIO cell signalling protein K26544 SEC14; phosphatidylinositol/phosphatidylcholine transfer protein
C Chro.60183 sec14-like CRAL/TRIO domain protein K26544 SEC14; phosphatidylinositol/phosphatidylcholine transfer protein
!
#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 13, 2024
#
ABC classifications based on Igarashi et al. (2004) and Tomii & Kanehisa (1998)
#
MFS classification taken from TCDB