+E Ubiquitin system KO
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Ubiquitin System - Debaryomyces hansenii
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AUbiquitins and ubiquitin-like proteins
B Ubiquitins
C DEHA2F02816g DEHA2F02816p K08770 UBC; ubiquitin C
C DEHA2E18788g DEHA2E18788p K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e
C DEHA2G16082g ubiquitin-40S ribosomal protein S31 fusion protein K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae
B Ubiquitin-like proteins (UBLs)
C DEHA2D07194g DEHA2D07194p K12158 NEDD8; ubiquitin-like protein Nedd8
C DEHA2F21582g 40S ribosomal protein S30 K02983 RP-S30e; small subunit ribosomal protein S30e
C DEHA2D03960g DEHA2D03960p K08341 GABARAP; GABA(A) receptor-associated protein
C DEHA2C14036g DEHA2C14036p K08336 ATG12; ubiquitin-like protein ATG12
C DEHA2B15466g DEHA2B15466p K12161 URM1; ubiquitin related modifier 1
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AUbiquitin-activating enzymes (E1)
B Ubiquitin activating enzyme
C DEHA2F17204g DEHA2F17204p K03178 UBE1; ubiquitin-activating enzyme E1 [EC:6.2.1.45]
B UBL-activating enzymes
C DEHA2E02354g DEHA2E02354p K10684 UBLE1A; ubiquitin-like 1-activating enzyme E1 A [EC:6.2.1.45]
C DEHA2G15114g DEHA2G15114p K10685 UBLE1B; ubiquitin-like 1-activating enzyme E1 B [EC:6.2.1.45]
C DEHA2G05126g DEHA2G05126p K10686 UBA3; NEDD8-activating enzyme E1 [EC:6.2.1.64]
C DEHA2D07766g DEHA2D07766p K04532 NAE1; NEDD8-activating enzyme E1 regulatory subunit
C DEHA2G14696g DEHA2G14696p K11996 MOCS3; adenylyltransferase and sulfurtransferase [EC:2.7.7.80 2.8.1.11]
C DEHA2G23518g DEHA2G23518p K08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7
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AUbiquitin-conjugating enzymes (E2)
B Ubiquitin-conjugating enzymes
C DEHA2C13904g DEHA2C13904p K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
C DEHA2G06270g DEHA2G06270p K06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]
C DEHA2A02530g DEHA2A02530p K04555 UBE2G2; ubiquitin-conjugating enzyme E2 G2 [EC:2.3.2.23]
C DEHA2B06512g DEHA2B06512p K10576 UBE2H; ubiquitin-conjugating enzyme E2 H [EC:2.3.2.23]
C DEHA2A09746g DEHA2A09746p K04554 UBE2J2; ubiquitin-conjugating enzyme E2 J2 [EC:2.3.2.23]
C DEHA2E02222g DEHA2E02222p K04554 UBE2J2; ubiquitin-conjugating enzyme E2 J2 [EC:2.3.2.23]
C DEHA2E01562g DEHA2E01562p K04649 UBE2K; ubiquitin-conjugating enzyme (huntingtin interacting protein 2) [EC:2.3.2.23]
C DEHA2E12320g DEHA2E12320p K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C DEHA2C03168g DEHA2C03168p K02207 UBE2R; ubiquitin-conjugating enzyme E2 R [EC:2.3.2.23]
C DEHA2D14168g DEHA2D14168p K10689 PEX4; peroxin-4 [EC:2.3.2.23]
B UBL-conjugating enzymes
C DEHA2A11352g DEHA2A11352p K10577 UBE2I; ubiquitin-conjugating enzyme E2 I
C DEHA2C12694g DEHA2C12694p K10579 UBE2M; ubiquitin-conjugating enzyme E2 M [EC:2.3.2.34]
C DEHA2D09900g DEHA2D09900p K08343 ATG3; ubiquitin-like-conjugating enzyme ATG3
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AUbiquitin ligases (E3)
B HECT type E3
C DEHA2G21824g DEHA2G21824p K10589 UBE3C; ubiquitin-protein ligase E3 C [EC:2.3.2.26]
C DEHA2F05082g DEHA2F05082p K20803 UBE3D; ubiquitin-protein ligase E3 D [EC:2.3.2.26]
C DEHA2E20042g DEHA2E20042p K10590 TRIP12; E3 ubiquitin-protein ligase TRIP12 [EC:2.3.2.26]
C DEHA2D03718g DEHA2D03718p K10591 NEDD4; E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26]
C DEHA2G05544g DEHA2G05544p K10592 HUWE1; E3 ubiquitin-protein ligase HUWE1 [EC:2.3.2.26]
C DEHA2F11704g DEHA2F11704p K12232 HECTD2; E3 ubiquitin-protein ligase HECTD2 [EC:2.3.2.26]
C HECT type E3 associated proteins
B U-box type E3
C DEHA2B14366g DEHA2B14366p K10597 UBE4B; ubiquitin conjugation factor E4 B [EC:2.3.2.27]
C DEHA2F03058g DEHA2F03058p K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]
B Single Ring-finger type E3
C BRE1 proteins
D DEHA2B07986g DEHA2B07986p K10696 BRE1; E3 ubiquitin-protein ligase BRE1 [EC:2.3.2.27]
C CBL proteins
C SINA (Seven in absentia) proteins
C Ligand of Numb proteins
C March proteins
D DEHA2D06424g DEHA2D06424p K10661 MARCH6; E3 ubiquitin-protein ligase MARCH6 [EC:2.3.2.27]
C MDM2/MDM4 proteins
C NFX1 proteins
D DEHA2C16764g DEHA2C16764p K12236 NFX1; transcriptional repressor NF-X1
C Pellino proteins
C Peripheral membrane proteins
D DEHA2F09174g DEHA2F09174p K13346 PEX10; peroxin-10
D DEHA2A01298g DEHA2A01298p K13345 PEX12; peroxin-12
D DEHA2C05038g DEHA2C05038p K06664 PEX2; peroxin-2
C RBR proteins
D DEHA2B01320g DEHA2B01320p K11968 ARIH1; ariadne-1 [EC:2.3.2.31]
D DEHA2B08756g DEHA2B08756p K11971 RNF14; E3 ubiquitin-protein ligase RNF14 [EC:2.3.2.31]
C TRAF proteins
C TRIM/RBCC proteins
C UBR box proteins
D DEHA2G18568g DEHA2G18568p K10625 UBR1; E3 ubiquitin-protein ligase UBR1 [EC:2.3.2.27]
D DEHA2G18590g DEHA2G18590p K10625 UBR1; E3 ubiquitin-protein ligase UBR1 [EC:2.3.2.27]
D DEHA2F21472g DEHA2F21472p K11979 UBR7; E3 ubiquitin-protein ligase UBR7 [EC:2.3.2.27]
C ATL proteins
C Other single Ring-finger type E3
D DEHA2G03454g DEHA2G03454p K10632 BRAP; BRCA1-associated protein [EC:2.3.2.27]
D DEHA2F20328g DEHA2F20328p K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]
D DEHA2E18480g DEHA2E18480p K22377 LTN1; E3 ubiquitin-protein ligase listerin [EC:2.3.2.27]
D DEHA2F12298g DEHA2F12298p K10627 RAD18; E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27]
D DEHA2F05896g DEHA2F05896p K26979 RNF10; E3 ubiquitin-protein ligase RNF10 [EC:2.3.2.27]
D DEHA2G08008g DEHA2G08008p K11984 SART1; U4/U6.U5 tri-snRNP-associated protein 1
D DEHA2F23870g DEHA2F23870p K15710 SHPRH; E3 ubiquitin-protein ligase SHPRH [EC:5.6.2.- 2.3.2.27]
D DEHA2F21362g DEHA2F21362p K10601 SYVN1; E3 ubiquitin-protein ligase synoviolin [EC:2.3.2.27]
D DEHA2E05852g DEHA2E05852p K10601 SYVN1; E3 ubiquitin-protein ligase synoviolin [EC:2.3.2.27]
D DEHA2F15752g DEHA2F15752p K22381 ZNF598; E3 ubiquitin-protein ligase ZNF598 [EC:2.3.2.27]
D DEHA2D07788g DEHA2D07788p K16275 BAH; E3 ubiquitin-protein ligase BAH [EC:2.3.2.27]
D DEHA2G06710g DEHA2G06710p K23788 TUL1; transmembrane E3 ubiquitin-protein ligase [EC:2.3.2.27]
D DEHA2A08118g DEHA2A08118p K23787 DMA1_2; E3 ubiquitin-protein ligase DMA1/2 [EC:2.3.2.27]
B Atypical E3
C DEHA2G20724g DEHA2G20724p K22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]
B UBL E3 ligases
C DEHA2F17666g DEHA2F17666p K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
C DEHA2G07568g DEHA2G07568p K04706 PIAS1; E3 SUMO-protein ligase PIAS1 [EC:2.3.2.-]
C DEHA2C17182g DEHA2C17182p K22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]
C DEHA2F04620g DEHA2F04620p K17822 DCUN1D1_2; DCN1-like protein 1/2
B Multi subunit Ring-finger type E3
C SCF complex
D Ring finger protein
E DEHA2F17666g DEHA2F17666p K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E DEHA2D15444g DEHA2D15444p K03347 CUL1; cullin 1
D Adaptor protein
E DEHA2F26004g DEHA2F26004p K03094 SKP1; S-phase kinase-associated protein 1
D Target recognizing subunit (F-box)
E DEHA2D14652g DEHA2D14652p K10259 MET30; F-box and WD-40 domain protein MET30
E DEHA2F07392g DEHA2F07392p K03361 CDC4; F-box and WD-40 domain protein CDC4
E DEHA2B08250g DEHA2B08250p K10273 FBXL7; F-box and leucine-rich repeat protein 7
E DEHA2B02464g DEHA2B02464p K10276 FBXL10_11; F-box and leucine-rich repeat protein 10/11 [EC:1.14.11.27]
E DEHA2G24486g DEHA2G24486p K03360 GRR1; F-box and leucine-rich repeat protein GRR1
E DEHA2E05346g DEHA2E05346p K15068 DIA2; protein DIA2
E DEHA2G02772g DEHA2G02772p K10295 FBXO9; F-box protein 9
E DEHA2E19052g DEHA2E19052p K15071 RCY1; recyclin-1
E DEHA2E06644g DEHA2E06644p K15072 SAF1; SCF-associated factor 1
E DEHA2A03124g DEHA2A03124p K15073 UFO1; ubiquitin ligase complex F-box protein UFO1
C Cul2 complex
D Ring finger protein
E DEHA2F17666g DEHA2F17666p K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
D Adoptor protein
E DEHA2D13046g DEHA2D13046p K03872 ELOC; elongin-C
D Target recognizing subunit
C Cul3 complex
D Ring finger protein
E DEHA2F17666g DEHA2F17666p K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E DEHA2C11638g DEHA2C11638p K03869 CUL3; cullin 3
D Adoptor and target recognizing subunit (BTB)
E DEHA2F22154g DEHA2F22154p K10520 ABTB1; ankyrin repeat and BTB/POZ domain-containing protein 1
C Cul4 complex
D Ring finger protein
E DEHA2F17666g DEHA2F17666p K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E DEHA2C08426g DEHA2C08426p K10609 CUL4; cullin 4
D Adoptor protein
D Target recognizing subunit (DCAF)
E DEHA2G01716g DEHA2G01716p K10570 ERCC8; DNA excision repair protein ERCC-8
E DEHA2F03784g DEHA2F03784p K11805 DCAF7; DDB1- and CUL4-associated factor 7
E DEHA2C12452g DEHA2C12452p K11806 DCAF13; DDB1- and CUL4-associated factor 13
E DEHA2E23650g DEHA2E23650p K22382 WDR26; WD repeat-containing protein 26
E DEHA2F21868g DEHA2F21868p K24755 WDR76; WD repeat-containing protein 76
C Cul5 complex
D Ring finger protein
D Cullin
D Adoptor protein
E DEHA2D13046g DEHA2D13046p K03872 ELOC; elongin-C
D Target recognizing subunit
C Cul7 complex
D Ring finger protein
E DEHA2F17666g DEHA2F17666p K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
D Adaptor protein
E DEHA2F26004g DEHA2F26004p K03094 SKP1; S-phase kinase-associated protein 1
D Target recognizing subunit
C Cul8 complex
D Ring finger protein
E DEHA2F17666g DEHA2F17666p K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
D Adaptor protein
D Target recognizing subunit
E DEHA2C11594g DEHA2C11594p K26122 MMS22; E3 ubiquitin-protein ligase substrate receptor MMS22
C Cul9 complex
D Ring finger protein
E DEHA2F17666g DEHA2F17666p K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
C APC/C
D Ring finger protein
E DEHA2A13772g DEHA2A13772p K03358 APC11; anaphase-promoting complex subunit 11
D Cullin
E DEHA2F04642g DEHA2F04642p K03349 APC2; anaphase-promoting complex subunit 2
D Target recognizing subunit
E DEHA2E20966g DEHA2E20966p K03363 CDC20; cell division cycle 20, cofactor of APC complex
E DEHA2A06864g DEHA2A06864p K03364 CDH1; cell division cycle 20-like protein 1, cofactor of APC complex
E DEHA2B14498g DEHA2B14498p K12782 AMA1; meiosis-specific APC/C activator protein AMA1
D Other subunits
E DEHA2D08932g DEHA2D08932p K03348 APC1; anaphase-promoting complex subunit 1
E DEHA2F20614g DEHA2F20614p K03350 APC3; anaphase-promoting complex subunit 3
E DEHA2B08316g DEHA2B08316p K03351 APC4; anaphase-promoting complex subunit 4
E DEHA2C08668g DEHA2C08668p K03352 APC5; anaphase-promoting complex subunit 5
E DEHA2C07062g DEHA2C07062p K03353 APC6; anaphase-promoting complex subunit 6
E DEHA2E02156g DEHA2E02156p K03355 APC8; anaphase-promoting complex subunit 8
E DEHA2F26400g DEHA2F26400p K03357 APC10; anaphase-promoting complex subunit 10
C BRCC complex
D DEHA2C16698g DEHA2C16698p K04482 RAD51; DNA repair protein RAD51
C KPC complex
C LUBAC complex
C CTLH complex
D DEHA2D13024g DEHA2D13024p K23333 RMND5; E3 ubiquitin-protein transferase RMND5 [EC:2.3.2.27]
D DEHA2A10076g DEHA2A10076p K18624 MAEA; macrophage erythroblast attacher
D DEHA2F17336g DEHA2F17336p K23335 GID4; glucose-induced degradation protein 4
D DEHA2D12188g DEHA2D12188p K23338 GID8; glucose-induced degradation protein 8
D DEHA2E23650g DEHA2E23650p K22382 WDR26; WD repeat-containing protein 26
C ERAD complex
C LMBR1L-GP78-UBAC2 complex
C SLX5-SLX8 complex
D DEHA2E08690g DEHA2E08690p K22645 SLX5; E3 ubiquitin-protein ligase complex SLX5-SLX8 subunit SLX5 [EC:2.3.2.27]
D DEHA2C04928g DEHA2C04928p K22646 SLX8; E3 ubiquitin-protein ligase complex SLX5-SLX8 subunit SLX8 [EC:2.3.2.27]
C Multi subunit type E3 associated proteins
D DEHA2F07172g DEHA2F07172p K17263 CAND1; cullin-associated NEDD8-dissociated protein 1
D DEHA2F25960g DEHA2F25960p K24350 UBXN7; UBX domain-containing protein 7
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ADeubiquitinating enzyme (DUB)
B Ubiquitin-specific proteases (UBPs)
C UCH
D DEHA2G15312g DEHA2G15312p K05609 UCHL3; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]
D DEHA2G19690g DEHA2G19690p K05610 UCHL5; ubiquitin carboxyl-terminal hydrolase L5 [EC:3.4.19.12]
C UBP/USP
D DEHA2G15598g DEHA2G15598p K11835 USP4_11; ubiquitin carboxyl-terminal hydrolase 4/11 [EC:3.4.19.12]
D DEHA2G08844g DEHA2G08844p K11836 USP5_13; ubiquitin carboxyl-terminal hydrolase 5/13 [EC:3.4.19.12]
D DEHA2C12936g DEHA2C12936p K11838 USP7; ubiquitin carboxyl-terminal hydrolase 7 [EC:3.4.19.12]
D DEHA2F24882g DEHA2F24882p K11839 USP8; ubiquitin carboxyl-terminal hydrolase 8 [EC:3.4.19.12]
D DEHA2A07942g DEHA2A07942p K11841 USP10; ubiquitin carboxyl-terminal hydrolase 10 [EC:3.4.19.12]
D DEHA2G09328g DEHA2G09328p K11843 USP14; ubiquitin carboxyl-terminal hydrolase 14 [EC:3.4.19.12]
D DEHA2C12804g DEHA2C12804p K11366 USP22_27_51; ubiquitin carboxyl-terminal hydrolase 22/27/51 [EC:3.4.19.12]
D DEHA2G10494g DEHA2G10494p K11849 USP25; ubiquitin carboxyl-terminal hydrolase 25 [EC:3.4.19.12]
D DEHA2A10032g DEHA2A10032p K11870 UBP1; ubiquitin carboxyl-terminal hydrolase 1 [EC:3.4.19.12]
D DEHA2E03322g DEHA2E03322p K11871 UBP7_11; ubiquitin carboxyl-terminal hydrolase 7/11 [EC:3.4.19.12]
D DEHA2D18766g DEHA2D18766p K11872 UBP9_13; ubiquitin carboxyl-terminal hydrolase 9/13 [EC:3.4.19.12]
D DEHA2F03520g DEHA2F03520p K11873 UBP10; ubiquitin carboxyl-terminal hydrolase 10 [EC:3.4.19.12]
D DEHA2D05698g DEHA2D05698p K11874 UBP16; ubiquitin carboxyl-terminal hydrolase 16 [EC:3.4.19.12]
C OTU
D DEHA2E11990g DEHA2E11990p K18342 OTUD6; OTU domain-containing protein 6 [EC:3.4.19.12]
C MJD
C MINDY
D DEHA2D02530g DEHA2D02530p K01309 MINDY1_2; ubiquitin carboxyl-terminal hydrolase MINDY-1/2 [EC:3.4.19.12]
C JAMM
D DEHA2F25146g DEHA2F25146p K03030 PSMD14; 26S proteasome regulatory subunit N11
C PPPDE
C ZUFSP
C BRISC complex
B UBL-specific proteases (ULPs)
C DEHA2F20130g DEHA2F20130p K08592 SENP1; sentrin-specific protease 1 [EC:3.4.22.68]
C DEHA2C06028g DEHA2C06028p K08596 SENP7; sentrin-specific protease 7 [EC:3.4.22.68]
C DEHA2B13772g DEHA2B13772p K08597 SENP8; sentrin-specific protease 8 [EC:3.4.22.68]
C DEHA2G15312g DEHA2G15312p K05609 UCHL3; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]
C DEHA2G12276g DEHA2G12276p K22762 DESI1; desumoylating isopeptidase 1 [EC:3.4.-.-]
C COP9 signalosome (CSN) complex
D DEHA2B11176g DEHA2B11176p K12176 COPS2; COP9 signalosome complex subunit 2
D DEHA2F03498g DEHA2F03498p K09613 COPS5; COP9 signalosome complex subunit 5 [EC:3.4.-.-]
D DEHA2G24442g DEHA2G24442p K24364 CSN12; COP9 signalosome complex subunit 12
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: May 1, 2024