+E Messenger RNA Biogenesis KO
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Messenger RNA Biogenesis - Drosophila melanogaster (fruit fly)
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AEukaryotic type
B mRNA processing factors
C 5' end processing
D Capping factors
E Dmel_CG3688 Rnmt; RNA guanine-7 methyltransferase K00565 RNMT; mRNA (guanine-N7-)-methyltransferase [EC:2.1.1.56]
E Dmel_CG1810 mRNA-cap; mRNA-capping-enzyme K13917 RNGTT; mRNA-capping enzyme [EC:2.7.7.50 3.6.1.74]
E Dmel_CG3319 Cdk7; Cyclin-dependent kinase 7 K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
E Dmel_CG6379 Cmtr1; Cap methyltransferase 1, isoform B K14589 CMTR1; cap1 methyltransferase [EC:2.1.1.57]
E Dmel_CG5032 aft; adrift K14590 CMTR2; cap2 methyltransferase [EC:2.1.1.296]
E Dmel_CG13807 CG13807; uncharacterized protein K18708 FAM103A1; RNMT-activating mini protein
D Cap binding complex
E Dmel_CG7035 Cbp80; cap binding protein 80, isoform B K12882 NCBP1; nuclear cap-binding protein subunit 1
E Dmel_CG7907 CG7907; uncharacterized protein, isoform B K12882 NCBP1; nuclear cap-binding protein subunit 1
E Dmel_CG12357 Cbp20; cap binding protein 20 K12883 NCBP2; nuclear cap-binding protein subunit 2
C 3' end processing
D Pre-mRNA cleavage factor Im (CFIm)
E Dmel_CG3689 Cpsf5; cleavage and polyadenylation specific factor 5, isoform C K14397 NUDT21; cleavage and polyadenylation specificity factor subunit 5
E Dmel_CG7185 Cpsf6; cleavage and polyadenylation specific factor 6, isoform A K14398 CPSF6_7; cleavage and polyadenylation specificity factor subunit 6/7
D Pre-mRNA cleavage factor IIm (CFIIm)
E Dmel_CG5970 cbc; crowded by cid K14399 CLP1; polyribonucleotide 5'-hydroxyl-kinase [EC:2.7.1.78]
E Dmel_CG10228 Pcf11; Pcf11 cleavage and polyadenylation factor subunit, isoform B K14400 PCF11; pre-mRNA cleavage complex 2 protein Pcf11
D Cleavage and polyadenylation specificity factor (CPSF) complex
E Dmel_CG10110 Cpsf160; cleavage and polyadenylation specificity factor 160, isoform A K14401 CPSF1; cleavage and polyadenylation specificity factor subunit 1
E Dmel_CG1957 Cpsf100; cleavage and polyadenylation specificity factor 100 K14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2
E Dmel_CG7698 Cpsf73; cleavage and polyadenylation specificity factor 73 K14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]
E Dmel_CG3642 Clp; clipper K14404 CPSF4; cleavage and polyadenylation specificity factor subunit 4
E Dmel_CG1078 Fip1; factor interacting with poly(A) polymerase 1 K14405 FIP1L1; pre-mRNA 3'-end-processing factor FIP1
E Dmel_CG1109 Wdr33; WD repeat domain 33, isoform A K15542 PFS2; polyadenylation factor subunit 2
E Dmel_CG17293 Wdr82; WD repeat domain 82 K14962 WDR82; COMPASS component SWD2
E Dmel_CG3515 CG3515; uncharacterized protein K14962 WDR82; COMPASS component SWD2
E Dmel_CG2096 flw; flapwing, isoform C K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E Dmel_CG5650 Pp1-87B; protein phosphatase 1 at 87B K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E Dmel_CG6593 Pp1alpha-96A; protein phosphatase 1alpha at 96A, isoform B K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E Dmel_CG9156 Pp1-13C; protein phosphatase 1 at 13C K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E Dmel_CG3245 PpN58A; protein phosphatase N at 58A K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E Dmel_CG41534 Pp1-Y1; protein phosphatase 1, Y-linked 1 K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E Dmel_CG10138 PpD5; protein phosphatase D5 K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E Dmel_CG8822 PpD6; protein phosphatase D6 K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E Dmel_CG40448 Pp1-Y2; protein phosphatase 1, Y-linked 2 K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E Dmel_CG10930 PpY-55A; protein phosphatase Y at 55A, isoform B K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E Dmel_CG14216 Ssu72; Ssu72 CTD phosphatase, isoform B K15544 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16]
D Cleavage stimulation factor (CSTF) complex
E Dmel_CG2261 CstF50; cleavage stimulation factor 50 kD subunit K14406 CSTF1; cleavage stimulation factor subunit 1
E Dmel_CG7697 CstF64; cleavage stimulation factor 64 kD subunit K14407 CSTF2; cleavage stimulation factor subunit 2
E Dmel_CG17170 su(f); suppressor of forked, isoform F K14408 CSTF3; cleavage stimulation factor subunit 3
E Dmel_CG2097 Sym; symplekin K06100 SYMPK; symplekin
D U7-dependent histone pre-mRNA processing factors
E Dmel_CG5352 SmB; small ribonucleoprotein particle protein SmB K11086 SNRPB; small nuclear ribonucleoprotein B and B'
E Dmel_CG8427 SmD3; small ribonucleoprotein particle protein SmD3 K11088 SNRPD3; small nuclear ribonucleoprotein D3
E Dmel_CG18591 SmE; small ribonucleoprotein particle protein SmE K11097 SNRPE; small nuclear ribonucleoprotein E
E Dmel_CG16792 SmF; small ribonucleoprotein particle protein SmF K11098 SNRPF; small nuclear ribonucleoprotein F
E Dmel_CG9742 SNRPG; small nuclear ribonucleoprotein G, isoform B K11099 SNRPG; small nuclear ribonucleoprotein G
E Dmel_CG12938 Lsm10; Lsm10 K25591 LSM10; U7 snRNA-associated Sm-like protein LSm10
E Dmel_CG12924 Lsm11; Lsm11 K25592 LSM11; U7 snRNA-associated Sm-like protein LSm11
E Dmel_CG1957 Cpsf100; cleavage and polyadenylation specificity factor 100 K14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2
E Dmel_CG7698 Cpsf73; cleavage and polyadenylation specificity factor 73 K14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]
E Dmel_CG7697 CstF64; cleavage stimulation factor 64 kD subunit K14407 CSTF2; cleavage stimulation factor subunit 2
E Dmel_CG2097 Sym; symplekin K06100 SYMPK; symplekin
E Dmel_CG11886 Slbp; Stem-loop binding protein K18710 SLBP; histone RNA hairpin-binding protein
E Dmel_CG4616 FLASH; FLICE-associated huge protein, isoform A K25593 CASP8AP2; CASP8-associated protein 2
D DRB sensitivity inducing factor (DSIF) complex
E Dmel_CG12372 spt4; spt4 K15171 SUPT4H1; transcription elongation factor SPT4
E Dmel_CG7626 Spt5; Spt5 K15172 SUPT5H; transcription elongation factor SPT5
D N6-methyltransferase complex
E Dmel_CG5933 Mettl3; methyltransferase like 3 K05925 METTL3; mRNA m6A methyltransferase catalytic subunit [EC:2.1.1.348]
E Dmel_CG7818 Mettl14; methyltransferase like 14 K23960 METTL14; mRNA m6A methyltransferase non-catalytic subunit
E Dmel_CG14906 Mettl4; methyltransferase like 4 K24174 METTL4; N(6)-adenine-specific DNA methyltransferase [EC:2.1.1.72]
E Dmel_CG7544 CG7544; uncharacterized protein, isoform B K11393 METTL16; U6 snRNA m6A methyltransferase [EC:2.1.1.346]
E Dmel_CG6315 fl(2)d; female lethal d, isoform A K22824 WTAP; pre-mRNA-splicing regulator WTAP
E Dmel_CG3496 vir; virilizer K22910 VIRMA; protein virilizer
E Dmel_CG2910 nito; spenito, isoform C K13190 RBM15; RNA-binding protein 15
E Dmel_CG10263 Hakai; hakai, isoform F K15685 CBLL1; E3 ubiquitin-protein ligase Hakai [EC:2.3.2.27]
D Poly(A) addition factors
E Dmel_CG9854 hrg; hiiragi, isoform C K14376 PAP; poly(A) polymerase [EC:2.7.7.19]
E Dmel_CG5732 Gld2; GLD2 poly(A) polymerase, isoform C K14079 PAPD4; poly(A) RNA polymerase GLD2 [EC:2.7.7.19]
E Dmel_CG15737 wisp; wispy, isoform C K14079 PAPD4; poly(A) RNA polymerase GLD2 [EC:2.7.7.19]
D Negative regulators of mRNA 3' end processing
E Dmel_CG10084 swm; second mitotic wave missing, isoform A K13192 RBM26; RNA-binding protein 26
E Dmel_CG10327 TBPH; TAR DNA-binding protein-43 homolog, isoform E K23600 TARDBP; TAR DNA-binding protein 43
E Dmel_CG7804 cocoon; cocoon, isoform B K23600 TARDBP; TAR DNA-binding protein 43
C Other processing factors
D Dmel_CG5649 kin17; kin17 K13102 KIN; DNA/RNA-binding protein KIN17
D Dmel_CG10584 CG10584; uncharacterized protein K23040 METTL22; methyltransferase-like protein 22 [EC:2.1.1.-]
D Dmel_CG46385 CG46385; uncharacterized protein, isoform C K23034 TENT5C; terminal nucleotidyltransferase 5C [EC:2.7.7.19]
D Dmel_CG5720 Nab2; nuclear polyadenosine RNA-binding 2 K23038 ZC3H14; zinc finger CCCH domain-containing protein 14
D Dmel_CG7843 Ars2; arsenic resistance protein 2, isoform A K27103 SRRT; serrate RNA effector molecule
B mRNA surveillance and transport factors
C Transport factors
D EJC complex
E Dmel_CG8781 tsu; tsunagi K12876 RBM8A; RNA-binding protein 8A
E Dmel_CG9401 mago; mago nashi K12877 MAGOH; protein mago nashi
E Dmel_CG1101 Ref1; RNA and export factor binding protein 1 K12881 THOC4; THO complex subunit 4
E Dmel_CG17031 Ref2; RNA and export factor binding protein 2, isoform B K12881 THOC4; THO complex subunit 4
E Dmel_CG7269 Hel25E; helicase at 25E, isoform A K12812 DDX39B; ATP-dependent RNA helicase UAP56/SUB2 [EC:5.6.2.7]
E Dmel_CG7483 CG7483; uncharacterized protein K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]
E Dmel_CG7183 CG7183; uncharacterized protein, isoform B K25178 CCDC174; coiled-coil domain-containing protein 174
E Dmel_CG12878 btz; barentsz, isoform C K14323 CASC3; protein CASC3
E Dmel_CG6046 Bin1; bicoid interacting protein 1, isoform B K14324 SAP18; histone deacetylase complex subunit SAP18
E Dmel_CG8383 Pnn; pinin, isoform B K13114 PNN; pinin
E Dmel_CG10473 Acn; acinus, isoform C K12875 ACIN1; apoptotic chromatin condensation inducer in the nucleus
E Dmel_CG34334 CG34334; uncharacterized protein K14325 RNPS1; RNA-binding protein with serine-rich domain 1
E Dmel_CG16788 RnpS1; RNA-binding protein S1 K14325 RNPS1; RNA-binding protein with serine-rich domain 1
E Dmel_CG11274 Srrm1; Serine-arginine repetitive matrix 1 K13171 SRRM1; serine/arginine repetitive matrix protein 1
D TREX complex
E Dmel_CG2031 Hpr1; Hpr1 K12878 THOC1; THO complex subunit 1
E Dmel_CG31671 tho2; tho2, isoform C K12879 THOC2; THO complex subunit 2
E Dmel_CG9615 tex; tex K12880 THOC3; THO complex subunit 3
E Dmel_CG1101 Ref1; RNA and export factor binding protein 1 K12881 THOC4; THO complex subunit 4
E Dmel_CG17031 Ref2; RNA and export factor binding protein 2, isoform B K12881 THOC4; THO complex subunit 4
E Dmel_CG2980 thoc5; thoc5 K13174 THOC5; THO complex subunit 5
E Dmel_CG5632 thoc6; thoc6, isoform B K13175 THOC6; THO complex subunit 6
E Dmel_CG17143 thoc7; thoc7, isoform A K13176 THOC7; THO complex subunit 7
D TREX-2 complex
E Dmel_CG7351 PCID2; PCI domain-containing protein 2 K23801 PCID2; nuclear mRNA export protein PCID2/THP1
E Dmel_CG13779 Sem1; suppressor of exocyst mutations 1 K10881 SHFM1; 26 proteasome complex subunit DSS1
E Dmel_CG15191 e(y)2; enhancer of yellow 2 K11368 ENY2; enhancer of yellow 2 transcription factor
E Dmel_CG14612 e(y)2b; enhancer of yellow 2b, isoform B K11368 ENY2; enhancer of yellow 2 transcription factor
D Nuclear pore complex
E Dmel_CG8274 Mgtor; megator, isoform B K09291 TPR; nucleoprotein TPR
E Dmel_CG9862 Rae1; Rae1 K14298 RAE1; mRNA export factor
E Dmel_CG12782 CG12782; uncharacterized protein K14298 RAE1; mRNA export factor
E Dmel_CG6773 Sec13; secretory 13, isoform B K14004 SEC13; protein transport protein SEC13
E Dmel_CG11875 Nup37; nucleoporin 37kD, isoform B K14302 NUP37; nuclear pore complex protein Nup37
E Dmel_CG5733 Nup75; nucleoporin 75kD K14304 NUP85; nuclear pore complex protein Nup85
E Dmel_CG7671 Nup43; nucleoporin 43kD K14305 NUP43; nuclear pore complex protein Nup43
E Dmel_CG2158 Nup50; nucleoporin 50kD K14295 NUP50; nuclear pore complex protein Nup50
E Dmel_CG8831 Nup54; nucleoporin 54kD K14308 NUP54; nuclear pore complex protein Nup54
E Dmel_CG6251 Nup62; nucleoporin 62kD, isoform B K14306 NUP62; nuclear pore complex protein Nup62
E Dmel_CG6819 mbo; members only K14318 NUP88; nuclear pore complex protein Nup88
E Dmel_CG7262 Nup93-2; nucleoporin 93kD-2 K14309 NUP93; nuclear pore complex protein Nup93
E Dmel_CG11092 Nup93-1; nucleoporin 93kD-1 K14309 NUP93; nuclear pore complex protein Nup93
E Dmel_CG10198 Nup98-96; nucleoporin 98-96kD, isoform D K14297 NUP98; nuclear pore complex protein Nup98-Nup96
E Dmel_CG6743 Nup107; nucleoporin 107kD K14301 NUP107; nuclear pore complex protein Nup107
E Dmel_CG6958 Nup133; nucleoporin 133kD K14300 NUP133; nuclear pore complex protein Nup133
E Dmel_CG8771 Nup188; nucleoporin 188kDa, isoform C K14311 NUP188; nuclear pore complex protein Nup188
E Dmel_CG4453 Nup153; nucleoporin 153kD, isoform C K14296 NUP153; nuclear pore complex protein Nup153
E Dmel_CG4579 Nup154; nucleoporin 154kD, isoform D K14312 NUP155; nuclear pore complex protein Nup155
E Dmel_CG4738 Nup160; nucleoporin 160kD, isoform B K14303 NUP160; nuclear pore complex protein Nup160
E Dmel_CG6540 Nup35; nucleoporin 35kDa K14313 NUP35; nuclear pore complex protein Nup53
E Dmel_CG11943 Nup205; nucleoporin 205kD, isoform B K14310 NUP205; nuclear pore complex protein Nup205
E Dmel_CG7897 Gp210; glycoprotein 210 kDa, isoform B K14314 NUP210; nuclear pore complex protein Nup210
E Dmel_CG3820 Nup214; nucleoporin 214kD K14317 NUP214; nuclear pore complex protein Nup214
E Dmel_CG14712 CG14712; uncharacterized protein K14316 POM121; nuclear pore complex protein Nup121
E Dmel_CG7360 Nup58; nucleoporin 58kD K14307 NUPL1; nucleoporin p58/p45
E Dmel_CG18789 CG18789; uncharacterized protein K14321 NUPL2; nucleoporin-like protein 2
E Dmel_CG18787 CG18787; uncharacterized protein K14321 NUPL2; nucleoporin-like protein 2
E Dmel_CG5857 Ndc1; nuclear division cycle 1 K14315 NDC1; nucleoporin NDC1
E Dmel_CG8722 Nup44A; nucleoporin at 44A, isoform A K14299 SEH1; nucleoporin SEH1
E Dmel_CG11856 Nup358; nucleoporin 358kD, isoform B K12172 RANBP2; E3 SUMO-protein ligase RanBP2 [EC:2.3.2.-]
E Dmel_CG16892 Aladin; aladin, isoform B K14320 AAAS; aladin
E Dmel_CG13137 CG13137; uncharacterized protein K14320 AAAS; aladin
E Dmel_CG14749 Gle1; Gle1 RNA export mediator K18723 GLE1; nucleoporin GLE1
E Dmel_CG1664 sbr; small bristles, isoform A K14284 NXF; nuclear RNA export factor
E Dmel_CG32135 Nxf3; nuclear export factor 3, isoform E K14284 NXF; nuclear RNA export factor
E Dmel_CG31501 nxf4; nuclear export factor 4 K14284 NXF; nuclear RNA export factor
E Dmel_CG12752 Nxt1; NTF2-related export protein 1, isoform A K14285 NXT1_2; NTF2-related export protein 1/2
D Ran-mediated transport factors
E Dmel_CG1404 Ran; Ran, isoform C K07936 RAN; GTP-binding nuclear protein Ran
E Dmel_CG7815 Ran-like K07936 RAN; GTP-binding nuclear protein Ran
E Dmel_CG5784 Mapmodulin; mapmodulin, isoform B K18646 ANP32A_C_D; acidic leucine-rich nuclear phosphoprotein 32 family member A/C/D
E Dmel_CG3151 Rbp9; RNA-binding protein 9, isoform G K13208 ELAVL2_3_4; ELAV like protein 2/3/4
E Dmel_CG4262 elav; embryonic lethal abnormal vision, isoform D K13208 ELAVL2_3_4; ELAV like protein 2/3/4
E Dmel_CG4396 fne; found in neurons, isoform B K13208 ELAVL2_3_4; ELAV like protein 2/3/4
E Dmel_CG5213 maca; maca K13208 ELAVL2_3_4; ELAV like protein 2/3/4
E Dmel_CG10372 Faf2; Fas-associated factor 2, isoform B K18726 FAF2; FAS-associated factor 2
E Dmel_CG2331 TER94; transitional endoplasmic reticulum 94, isoform A K13525 VCP; transitional endoplasmic reticulum ATPase
E Dmel_CG13387 emb; embargoed, isoform B K14290 XPO1; exportin-1
E Dmel_CG33180 Ranbp16; Ranbp16, isoform H K18460 XPO7; exportin-7
E Dmel_CG9999 RanGAP; Ran GTPase activating protein, isoform B K14319 RANGAP1; Ran GTPase-activating protein 1
D eIF4F and regulatory proteins
E Dmel_CG1442 eIF4E6; eukaryotic translation initiation factor 4E6, isoform B K03259 EIF4E; translation initiation factor 4E
E Dmel_CG10124 eIF4E4; eukaryotic translation initiation factor 4E4 K03259 EIF4E; translation initiation factor 4E
E Dmel_CG4035 eIF4E1; eukaryotic translation initiation factor 4E1, isoform H K03259 EIF4E; translation initiation factor 4E
E Dmel_CG33100 eIF4EHP; eukaryotic translation initiation factor 4E homologous protein, isoform B K03259 EIF4E; translation initiation factor 4E
E Dmel_CG8023 eIF4E3; eukaryotic translation initiation factor 4E3 K03259 EIF4E; translation initiation factor 4E
E Dmel_CG32859 eIF4E7; eukaryotic translation initiation factor 4E7 K03259 EIF4E; translation initiation factor 4E
E Dmel_CG8277 eIF4E5; eukaryotic translation initiation factor 4E5 K03259 EIF4E; translation initiation factor 4E
E Dmel_CG9075 eIF4A; eukaryotic translation initiation factor 4A, isoform E K03257 EIF4A; translation initiation factor 4A
E Dmel_CG10811 eIF4G1; eukaryotic translation initiation factor 4G1, isoform B K03260 EIF4G; translation initiation factor 4G
E Dmel_CG3845 NAT1; NAT1, isoform D K03260 EIF4G; translation initiation factor 4G
E Dmel_CG10837 eIF4B; eukaryotic translation initiation factor 4B, isoform B K03258 EIF4B; translation initiation factor 4B
E Dmel_CG1340 eIF4H2; eukaryotic translation initiation factor 4H2, isoform C K24086 EIF4H; translation initiation factor 4H
E Dmel_CG4429 eIF4H1; eukaryotic translation initiation factor 4H1, isoform D K24086 EIF4H; translation initiation factor 4H
E Dmel_CG8846 Thor; thor, isoform B K18644 EIF4EBP2; eukaryotic translation initiation factor 4E binding protein 2
E Dmel_CG32016 4E-T; eIF4E-Transporter, isoform G K18728 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter
E Dmel_CG12273 angel; angel K18729 ANGEL; protein angel
E Dmel_CG6203 Fmr1; fragile X messenger ribonucleoprotein 1, isoform A K15516 FMR; fragile X mental retardation protein
E Dmel_CG4931 Cyfip; cytoplasmic FMR1 interacting protein K05749 CYFIP; cytoplasmic FMR1 interacting protein
E Dmel_CG9765 tacc; transforming acidic coiled-coil protein, isoform H K14283 TACC3; transforming acidic coiled-coil-containing protein 3
E Dmel_CG10868 orb; oo18 RNA-binding protein, isoform F K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E Dmel_CG43782 orb2; orb2, isoform D K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E Dmel_CG9748 bel; belle, isoform A K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]
E Dmel_CG11148 Gyf; gigyf, isoform G K18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein
E Dmel_CG5119 pAbp; poly(A) binding protein, isoform A K13126 PABPC; polyadenylate-binding protein
E Dmel_CG8963 Paip1; Poly(A) binding protein interacting protein 1, isoform C K14322 PAIP1; polyadenylate-binding protein-interacting protein 1
E Dmel_CG12358 Paip2; polyA-binding protein interacting protein 2, isoform B K27470 PAIP2; polyadenylate-binding protein-interacting protein 2
E Dmel_CG10210 tst; twister, isoform B K12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6]
E Dmel_CG8567 Deaf1; deformed epidermal autoregulatory factor-1, isoform D K23041 DEAF1; deformed epidermal autoregulatory factor 1
E Dmel_CG5941 MCTS1; malignant T cell amplified sequence 1, isoform B K07575 MCTS; malignant T-cell-amplified sequence
E Dmel_CG9099 DENR; density regulated protein, isoform B K24272 DENR; density-regulated protein
D APOBEC1-ACF complex
D Other transport factors
E Dmel_CG30176 Pym; partner of Y14 and mago K14294 WIBG; partner of Y14 and mago
E Dmel_CG9983 Hrb98DE; heterogeneous nuclear ribonucleoprotein at 98DE, isoform B K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E Dmel_CG12749 Hrb87F; heterogeneous nuclear ribonucleoprotein at 87F, isoform C K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E Dmel_CG32169 Rbp6; RNA-binding protein 6, isoform A K14411 MSI; RNA-binding protein Musashi
E Dmel_CG5099 msi; musashi, isoform C K14411 MSI; RNA-binding protein Musashi
E Dmel_CG10377 Hrb27C; heterogeneous nuclear ribonucleoprotein at 27C, isoform D K14411 MSI; RNA-binding protein Musashi
E Dmel_CG6354 Rb97D; ribonuclear protein at 97D, isoform I K14411 MSI; RNA-binding protein Musashi
E Dmel_CG9654 Rbp4; RNA-binding protein 4 K14411 MSI; RNA-binding protein Musashi
E Dmel_CG1898 HBS1; HBS1, isoform B K14416 HBS1; elongation factor 1 alpha-like protein
E Dmel_CG3959 pelo; pelota K06965 PELO; protein pelota
E Dmel_CG2163 Pabp2; Pabp2, isoform A K14396 PABPN1; polyadenylate-binding protein 2
E Dmel_CG17023 Dbp80; dead box protein 80, isoform B K18655 DDX19; ATP-dependent RNA helicase DDX19/DBP5 [EC:5.6.2.7]
E Dmel_CG6197 fand; fandango K12867 SYF1; pre-mRNA-splicing factor SYF1
E Dmel_CG8149 CG8149; uncharacterized protein K18732 SARNP; SAP domain-containing ribonucleoprotein
E Dmel_CG10480 Rcc1; regulator of chromosome condensation 1, isoform A K11493 RCC1; regulator of chromosome condensation
E Dmel_CG17386 Achl; achilles, isoform B K18733 LARP6; la-related protein 6
E Dmel_CG1507 Pur-alpha; Purine-rich binding protein-alpha, isoform E K21772 PURA; transcriptional activator protein Pur-alpha
E Dmel_CG18259 CG18259; uncharacterized protein K22414 POLDIP3; polymerase delta-interacting protein 3
E Dmel_CG6961 CG6961; uncharacterized protein K22414 POLDIP3; polymerase delta-interacting protein 3
E Dmel_CG6700 CG6700; uncharacterized protein, isoform B K23802 LENG8; SAC3 family protein LENG8/THP3
C Surveillance factors
D Surveillance complex
E Dmel_CG5605 eRF1; eukaryotic translation release factor 1, isoform A K03265 ETF1; peptide chain release factor subunit 1
E Dmel_CG6382 eRF3; eukaryotic translation release factor 3, isoform B K03267 ERF3; peptide chain release factor subunit 3
E Dmel_CG1559 Upf1; Upf1 RNA helicase, isoform B K14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3]
E Dmel_CG2253 Upf2; Upf2 K14327 UPF2; regulator of nonsense transcripts 2
E Dmel_CG11184 Upf3; Upf3, isoform D K14328 UPF3; regulator of nonsense transcripts 3
D Protein phosphatase 2A
E Dmel_CG7109 mts; microtubule star, isoform B K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
E Dmel_CG17291 Pp2A-29B; protein phosphatase 2A at 29B, isoform C K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
E Dmel_CG6235 tws; twins, isoform I K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
E Dmel_CG4733 CG4733; uncharacterized protein, isoform C K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
E Dmel_CG7913 wrd; well-rounded, isoform K K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
E Dmel_CG5643 wdb; widerborst, isoform H K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
E Dmel_CG32568 CG32568; uncharacterized protein, isoform C K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
D Other surveillance factors
E Dmel_CG32743 nonC; no-on-and-no-off transient C, isoform B K08873 SMG1; serine/threonine-protein kinase SMG1 [EC:2.7.11.1]
E Dmel_CG8954 Smg5; Smg5 nonsense mediated mRNA decay factor, isoform C K11125 SMG5; protein SMG5
E Dmel_CG6369 Smg6; Smg6 K11124 SMG6; protein SMG6 [EC:3.1.-.-]
E Dmel_CG6729 CG6729; uncharacterized protein K18734 SMG8; protein SMG8
E Dmel_CG3857 CG3857; uncharacterized protein K18735 SMG9; protein SMG9
E Dmel_CG11148 Gyf; gigyf, isoform G K18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein
E Dmel_CG7066 Sbp2; SECIS-binding protein 2 K19539 SECISBP2; selenocysteine insertion sequence-binding protein 2
E Dmel_CG32533 CG32533; uncharacterized protein, isoform B K20101 DHX34; ATP-dependent RNA helicase DHX34 [EC:5.6.2.6]
E Dmel_CG5729 Dgp-1; Dgp-1, isoform B K24887 GTPBP1; GTP-binding protein 1
C Factors involved in mRNA localization
D Cargo complex
E Dmel_CG1685 peng; penguin K14844 PUF6; pumilio homology domain family member 6
E Dmel_CG2146 didum; dilute class unconventional myosin, isoform A K10357 MYO5; myosin V
E Dmel_CG6605 BicD; bicaudal D, isoform C K18739 BICD; protein bicaudal D
E Dmel_CG4051 egl; egalitarian, isoform C K18740 EXD1; exonuclease 3'-5' domain-containing protein 1
D Factors that have mRNA localization signals
E Dmel_CG4027 Act5C; actin 5C, isoform D K05692 ACTB_G1; actin beta/gamma 1
E Dmel_CG12051 Act42A; actin 42A K05692 ACTB_G1; actin beta/gamma 1
E Dmel_CG10798 Myc; Myc, isoform B K04377 MYC; Myc proto-oncogene protein
E Dmel_CG1034 bcd; bicoid, isoform G K18659 BCD; homeotic protein bicoid
E Dmel_CG5187 Doc2; Dorsocross2 K10180 TBX6; T-box protein 6
E Dmel_CG5093 Doc3; Dorsocross3 K10180 TBX6; T-box protein 6
E Dmel_CG5133 Doc1; Dorsocross1, isoform B K10180 TBX6; T-box protein 6
E Dmel_CG5637 nanos; nanos, isoform A K18741 NANOS1; protein nanos 1
E Dmel_CG10901 osk; oskar, isoform A K18742 OSK; maternal effect protein oskar
E Dmel_CG3218 fs(1)K10; female sterile (1) K10 K02524 K10; DNA binding protein (fs(1)K10, female sterile(1)K10)
E Dmel_CG17610 grk; gurken K02447 GRK; protein gruken
E Dmel_CG6096 E(spl)m5-HLH; enhancer of split m5, helix-loop-helix K09090 HESN; hairy and enhancer of split, invertebrate
E Dmel_CG6494 hry; hairy, isoform B K09090 HESN; hairy and enhancer of split, invertebrate
E Dmel_CG8704 dpn; deadpan K09090 HESN; hairy and enhancer of split, invertebrate
E Dmel_CG14548 E(spl)mbeta-HLH; enhancer of split mbeta, helix-loop-helix K09090 HESN; hairy and enhancer of split, invertebrate
E Dmel_CG8328 E(spl)mdelta-HLH; enhancer of split mdelta, helix-loop-helix K09090 HESN; hairy and enhancer of split, invertebrate
E Dmel_CG8333 E(spl)mgamma-HLH; enhancer of split mgamma, helix-loop-helix K09090 HESN; hairy and enhancer of split, invertebrate
E Dmel_CG8346 E(spl)m3-HLH; enhancer of split m3, helix-loop-helix K09090 HESN; hairy and enhancer of split, invertebrate
E Dmel_CG8361 E(spl)m7-HLH; enhancer of split m7, helix-loop-helix K09090 HESN; hairy and enhancer of split, invertebrate
E Dmel_CG8365 E(spl)m8-HLH; enhancer of split m8, helix-loop-helix K09090 HESN; hairy and enhancer of split, invertebrate
D Trans-acting binding proteins
E Dmel_CG8912 Psi; P-element somatic inhibitor, isoform D K13210 FUBP; far upstream element-binding protein
E Dmel_CG8280 eEF1alpha1; eukaryotic translation elongation factor 1 alpha 1, isoform D K03231 EEF1A; elongation factor 1-alpha
E Dmel_CG1873 eEF1alpha2; eukaryotic translation elongation factor 1 alpha 2, isoform A K03231 EEF1A; elongation factor 1-alpha
E Dmel_CG11901 eEF1gamma; eukaryotic translation elongation factor 1 gamma, isoform C K03233 EEF1G; elongation factor 1-gamma
E Dmel_CG3365 drongo; drongo, isoform I K15044 AGFG1; Arf-GAP domain and FG repeats-containing protein 1
E Dmel_CG5753 stau; staufen, isoform A K17597 STAU; double-stranded RNA-binding protein Staufen
E Dmel_CG31000 heph; hephaestus, isoform L K13218 PTBP1; polypyrimidine tract-binding protein 1
E Dmel_CG16901 sqd; squid, isoform B K03102 SQD; squid
E Dmel_CG10868 orb; oo18 RNA-binding protein, isoform F K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E Dmel_CG43782 orb2; orb2, isoform D K02602 CPEB; cytoplasmic polyadenylation element-binding protein
D Other mRNA localization factors
E Dmel_CG6203 Fmr1; fragile X messenger ribonucleoprotein 1, isoform A K15516 FMR; fragile X mental retardation protein
E Dmel_CG4931 Cyfip; cytoplasmic FMR1 interacting protein K05749 CYFIP; cytoplasmic FMR1 interacting protein
E Dmel_CG7437 mub; mushroom-body expressed, isoform D K21444 PCBP3_4; poly(rC)-binding protein 3/4
E Dmel_CG18811 Capr; caprin, isoform B K18743 CAPRIN1; caprin-1
E Dmel_CG31762 bru1; bruno 1, isoform E K02177 BRU; bruno
E Dmel_CG8994 exu; exuperantia, isoform D K18745 EXU; maternal protein exuperantia
E Dmel_CG5654 yps; ypsilon schachtel, isoform B K09276 YBX1; Y-box-binding protein 1
E Dmel_CG11181 cup; cup, isoform C K18746 CUP; protein cup
E Dmel_CG43770 Sxl; Sex lethal, isoform L K18747 SXL; protein sex-lethal
C mRNA cycle factors
D Common to processing body (P body) and stress granule
E Dmel_CG3291 pcm; pacman, isoform B K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]
E Dmel_CG6671 AGO1; Argonaute-1, isoform D K11593 ELF2C; eukaryotic translation initiation factor 2C
E Dmel_CG7439 AGO2; argonaute 2, isoform B K11593 ELF2C; eukaryotic translation initiation factor 2C
E Dmel_CG1442 eIF4E6; eukaryotic translation initiation factor 4E6, isoform B K03259 EIF4E; translation initiation factor 4E
E Dmel_CG10124 eIF4E4; eukaryotic translation initiation factor 4E4 K03259 EIF4E; translation initiation factor 4E
E Dmel_CG4035 eIF4E1; eukaryotic translation initiation factor 4E1, isoform H K03259 EIF4E; translation initiation factor 4E
E Dmel_CG33100 eIF4EHP; eukaryotic translation initiation factor 4E homologous protein, isoform B K03259 EIF4E; translation initiation factor 4E
E Dmel_CG8023 eIF4E3; eukaryotic translation initiation factor 4E3 K03259 EIF4E; translation initiation factor 4E
E Dmel_CG32859 eIF4E7; eukaryotic translation initiation factor 4E7 K03259 EIF4E; translation initiation factor 4E
E Dmel_CG8277 eIF4E5; eukaryotic translation initiation factor 4E5 K03259 EIF4E; translation initiation factor 4E
E Dmel_CG1559 Upf1; Upf1 RNA helicase, isoform B K14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3]
E Dmel_CG9748 bel; belle, isoform A K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]
E Dmel_CG4916 me31B; maternal expression at 31B, isoform A K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7]
E Dmel_CG11360 CG11360; uncharacterized protein, isoform C K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
E Dmel_CG10686 tral; trailer hitch, isoform B K18749 LSM14; protein LSM14
E Dmel_CG5654 yps; ypsilon schachtel, isoform B K09276 YBX1; Y-box-binding protein 1
E Dmel_CG11063 jub; ajuba LIM protein, isoform B K16682 AJUBA; LIM domain-containing protein
E Dmel_CG6967 Mov10; Mov10 RISC complex RNA helicase, isoform C K18422 MOV10; helicase MOV-10 [EC:5.6.2.5]
E Dmel_CG7398 Tnpo; transportin, isoform D K18752 TNPO1; transportin-1
E Dmel_CG8219 CG8219; uncharacterized protein K18752 TNPO1; transportin-1
E Dmel_CG32743 nonC; no-on-and-no-off transient C, isoform B K08873 SMG1; serine/threonine-protein kinase SMG1 [EC:2.7.11.1]
E Dmel_CG8954 Smg5; Smg5 nonsense mediated mRNA decay factor, isoform C K11125 SMG5; protein SMG5
E Dmel_CG6369 Smg6; Smg6 K11124 SMG6; protein SMG6 [EC:3.1.-.-]
E Dmel_CG4070 Tis11; Tis11 zinc finger protein, isoform C K15308 TTP; tristetraprolin
E Dmel_CG17334 lin-28; lin-28 K18754 LIN28; protein lin-28
E Dmel_CG9995 htt; huntingtin, isoform B K04533 HD; huntingtin
E Dmel_CG4824 BicC; bicaudal C, isoform A K18756 BICC1; protein bicaudal C
E Dmel_CG9983 Hrb98DE; heterogeneous nuclear ribonucleoprotein at 98DE, isoform B K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E Dmel_CG12749 Hrb87F; heterogeneous nuclear ribonucleoprotein at 87F, isoform C K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E Dmel_CG4379 Pka-C1; protein kinase, cAMP-dependent, catalytic subunit 1, isoform D K04345 PKA; protein kinase A [EC:2.7.11.11]
E Dmel_CG12066 Pka-C2; protein kinase, cAMP-dependent, catalytic subunit 2, isoform B K04345 PKA; protein kinase A [EC:2.7.11.11]
E Dmel_CG42551 larp; La related protein, isoform G K18757 LARP1; la-related protein 1
E Dmel_CG5166 Atx2; Ataxin-2, isoform B K23625 ATXN2_2L; ataxin 2/2L
D P-body specific factors
E Dmel_CG6169 DCP2; decapping protein 2, isoform D K12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]
E Dmel_CG11183 DCP1; decapping protein 1, isoform B K12611 DCP1B; mRNA-decapping enzyme 1B [EC:3.-.-.-]
E Dmel_CG4279 LSm1; uncharacterized protein K12620 LSM1; U6 snRNA-associated Sm-like protein LSm1
E Dmel_CG10418 CG10418; uncharacterized protein K12621 LSM2; U6 snRNA-associated Sm-like protein LSm2
E Dmel_CG31184 LSm3; uncharacterized protein K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3
E Dmel_CG17768 CG17768; uncharacterized protein, isoform A K12623 LSM4; U6 snRNA-associated Sm-like protein LSm4
E Dmel_CG6610 CG6610; uncharacterized protein, isoform B K12624 LSM5; U6 snRNA-associated Sm-like protein LSm5
E Dmel_CG9344 CG9344; uncharacterized protein K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6
E Dmel_CG13277 LSm7; uncharacterized protein K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7
E Dmel_CG2021 CG2021; uncharacterized protein K12627 LSM8; U6 snRNA-associated Sm-like protein LSm8
E Dmel_CG5433 Klc; kinesin light chain, isoform B K10407 KLC; kinesin light chain
E Dmel_CG2146 didum; dilute class unconventional myosin, isoform A K10357 MYO5; myosin V
E Dmel_CG1913 alphaTub84B; alpha-Tubulin at 84B K07374 TUBA; tubulin alpha
E Dmel_CG9476 alphaTub85E; alpha-Tubulin at 85E K07374 TUBA; tubulin alpha
E Dmel_CG8308 alphaTub67C; alpha-Tubulin at 67C K07374 TUBA; tubulin alpha
E Dmel_CG2512 alphaTub84D; alpha-Tubulin at 84D K07374 TUBA; tubulin alpha
E Dmel_CG7794 CG7794; uncharacterized protein K07374 TUBA; tubulin alpha
E Dmel_CG10868 orb; oo18 RNA-binding protein, isoform F K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E Dmel_CG43782 orb2; orb2, isoform D K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E Dmel_CG9765 tacc; transforming acidic coiled-coil protein, isoform H K14283 TACC3; transforming acidic coiled-coil-containing protein 3
E Dmel_CG31992 gw; gawky, isoform A K18412 TNRC6; trinucleotide repeat-containing gene 6 protein
E Dmel_CG34407 Not1; Not1, isoform C K12604 CNOT1; CCR4-NOT transcription complex subunit 1
E Dmel_CG2161 Rga; regena, isoform A K12605 CNOT2; CCR4-NOT transcription complex subunit 2
E Dmel_CG15262 CG15262; uncharacterized protein K12605 CNOT2; CCR4-NOT transcription complex subunit 2
E Dmel_CG8426 Not3; CCR4-NOT transcription complex subunit 3, isoform B K12580 CNOT3; CCR4-NOT transcription complex subunit 3
E Dmel_CG31716 Cnot4; CCR4-NOT transcription complex subunit 4, isoform H K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]
E Dmel_CG31137 twin; twin, isoform C K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E Dmel_CG5684 Pop2; Pop2, isoform D K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E Dmel_CG8232 PAN2; Poly(A)-binding protein-dependent poly(A) ribonuclease 2, isoform A K12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4]
E Dmel_CG11486 PAN3; Poly(A) specific ribonuclease subunit PAN3, isoform G K12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3
E Dmel_CG9214 Tob; transducer of ERBB2, isoform C K14443 TOB; protein Tob/BTG
E Dmel_CG32016 4E-T; eIF4E-Transporter, isoform G K18728 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter
E Dmel_CG5208 Patr-1; protein associated with topo II related - 1, isoform B K12617 PATL1; DNA topoisomerase 2-associated protein PAT1
E Dmel_CG6311 Edc3; enhancer of decapping 3 K12615 EDC3; enhancer of mRNA-decapping protein 3
E Dmel_CG6181 Ge-1; Ge-1, isoform A K12616 EDC4; enhancer of mRNA-decapping protein 4
E Dmel_CG2253 Upf2; Upf2 K14327 UPF2; regulator of nonsense transcripts 2
E Dmel_CG11184 Upf3; Upf3, isoform D K14328 UPF3; regulator of nonsense transcripts 3
E Dmel_CG42396 wech; wech, isoform D K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
E Dmel_CG15105 tn; thin, isoform C K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
E Dmel_CG31155 Polr2G; RNA polymerase II subunit G K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7
E Dmel_CG6422 Ythdf; YTH N6-methyladenosine RNA binding protein, isoform D K20102 YTHDF; YTH domain-containing family protein
D Stress granule specific factors
E Dmel_CG34354 CG34354; uncharacterized protein, isoform F K13201 TIA1; nucleolysin TIA-1/TIAR
E Dmel_CG5422 Rox8; Rox8, isoform G K13201 TIA1; nucleolysin TIA-1/TIAR
E Dmel_CG34362 trv; trivet, isoform I K13201 TIA1; nucleolysin TIA-1/TIAR
E Dmel_CG5119 pAbp; poly(A) binding protein, isoform A K13126 PABPC; polyadenylate-binding protein
E Dmel_CG5753 stau; staufen, isoform A K17597 STAU; double-stranded RNA-binding protein Staufen
E Dmel_CG6203 Fmr1; fragile X messenger ribonucleoprotein 1, isoform A K15516 FMR; fragile X mental retardation protein
E Dmel_CG9412 rin; rasputin, isoform B K24983 G3BP2; Ras GTPase-activating protein-binding protein 2
E Dmel_CG7414 eIF2A; eukaryotic translation initiation factor 2A, isoform D K15026 EIF2A; translation initiation factor 2A
E Dmel_CG4878 eIF3b; eukaryotic translation initiation factor 3 subunit b, isoform B K03253 EIF3B; translation initiation factor 3 subunit B
E Dmel_CG9075 eIF4A; eukaryotic translation initiation factor 4A, isoform E K03257 EIF4A; translation initiation factor 4A
E Dmel_CG7483 CG7483; uncharacterized protein K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]
E Dmel_CG10837 eIF4B; eukaryotic translation initiation factor 4B, isoform B K03258 EIF4B; translation initiation factor 4B
E Dmel_CG10811 eIF4G1; eukaryotic translation initiation factor 4G1, isoform B K03260 EIF4G; translation initiation factor 4G
E Dmel_CG3845 NAT1; NAT1, isoform D K03260 EIF4G; translation initiation factor 4G
E Dmel_CG17596 S6kII; ribosomal protein S6 kinase II, isoform B K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E Dmel_CG7111 Rack1; receptor of activated protein kinase C 1, isoform C K14753 RACK1; guanine nucleotide-binding protein subunit beta-2-like 1 protein
E Dmel_CG1664 sbr; small bristles, isoform A K14284 NXF; nuclear RNA export factor
E Dmel_CG32135 Nxf3; nuclear export factor 3, isoform E K14284 NXF; nuclear RNA export factor
E Dmel_CG31501 nxf4; nuclear export factor 4 K14284 NXF; nuclear RNA export factor
E Dmel_CG6170 HDAC6; histone deacetylase 6, isoform D K11407 HDAC6; histone deacetylase 6 [EC:3.5.1.98]
E Dmel_CG13472 Tdrd3; tudor domain containing 3 K18404 TDRD3; tudor domain-containing protein 3
E Dmel_CG11505 Larp4B; La-related protein 4B, isoform B K18763 LARP4; la-related protein 4
B mRNA degradation factors
C 5'-3' decay
D Decapping complex
E Dmel_CG11183 DCP1; decapping protein 1, isoform B K12611 DCP1B; mRNA-decapping enzyme 1B [EC:3.-.-.-]
E Dmel_CG6169 DCP2; decapping protein 2, isoform D K12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]
E Dmel_CG4916 me31B; maternal expression at 31B, isoform A K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7]
E Dmel_CG6311 Edc3; enhancer of decapping 3 K12615 EDC3; enhancer of mRNA-decapping protein 3
E Dmel_CG6181 Ge-1; Ge-1, isoform A K12616 EDC4; enhancer of mRNA-decapping protein 4
E Dmel_CG5208 Patr-1; protein associated with topo II related - 1, isoform B K12617 PATL1; DNA topoisomerase 2-associated protein PAT1
D Lsm complex
E Dmel_CG4279 LSm1; uncharacterized protein K12620 LSM1; U6 snRNA-associated Sm-like protein LSm1
E Dmel_CG10418 CG10418; uncharacterized protein K12621 LSM2; U6 snRNA-associated Sm-like protein LSm2
E Dmel_CG31184 LSm3; uncharacterized protein K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3
E Dmel_CG17768 CG17768; uncharacterized protein, isoform A K12623 LSM4; U6 snRNA-associated Sm-like protein LSm4
E Dmel_CG6610 CG6610; uncharacterized protein, isoform B K12624 LSM5; U6 snRNA-associated Sm-like protein LSm5
E Dmel_CG9344 CG9344; uncharacterized protein K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6
E Dmel_CG13277 LSm7; uncharacterized protein K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7
E Dmel_CG2021 CG2021; uncharacterized protein K12627 LSM8; U6 snRNA-associated Sm-like protein LSm8
D 5' exonucleases
E Dmel_CG3291 pcm; pacman, isoform B K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]
E Dmel_CG10354 Rat1; Rat1 5'-3' exoribonuclease, isoform B K12619 XRN2; 5'-3' exoribonuclease 2 [EC:3.1.13.-]
D Other 5'-3' decay factors
E Dmel_CG2091 Dcps; decapping enzyme, scavenger K12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]
E Dmel_CG9425 Helz; helicase with zinc finger, isoform C K25168 HELZ; helicase with zinc finger domain [EC:5.6.2.-]
C 3'-5' decay
D Core exosome factors
E Dmel_CG6249 Csl4; Csl4 K07573 CSL4; exosome complex component CSL4
E Dmel_CG3931 Rrp4; Rrp4, isoform B K03679 RRP4; exosome complex component RRP4
E Dmel_CG31938 Rrp40; ribosomal RNA processing 40, isoform B K03681 RRP40; exosome complex component RRP40
E Dmel_CG15481 Ski6; Ski6, isoform B K11600 RRP41; exosome complex component RRP41
E Dmel_CG4043 Rrp46; Rrp46 K12590 RRP46; exosome complex component RRP46
E Dmel_CG8025 Mtr3; Mtr3 K12587 MTR3; exosome complex component MTR3
E Dmel_CG8395 Rrp42; Rrp42 K12589 RRP42; exosome complex component RRP42
E Dmel_CG9606 Rrp45; Rrp45, isoform B K03678 RRP45; exosome complex component RRP45
D Exosome cofactors
E Dmel_CG6413 Dis3; Dis3, isoform B K12585 DIS3; exosome complex exonuclease DIS3/RRP44 [EC:3.1.13.-]
E Dmel_CG7292 Rrp6; Rrp6, isoform B K12591 RRP6; exosome complex exonuclease RRP6 [EC:3.1.13.-]
E Dmel_CG8928 Rrp47; ribosomal RNA processing 47, isoform B K12592 C1D; exosome complex protein LRP1
E Dmel_CG9250 Mpp6; M-phase phosphoprotein 6, isoform B K12593 MPHOSPH6; M-phase phosphoprotein 6, animal type
D TRAMP complex
E Dmel_CG11265 Trf4-1; topoisomerase related function 4-1, isoform J K03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19]
E Dmel_CG17462 Trf4-2; topoisomerase related function 4-2, isoform B K03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19]
E Dmel_CG4152 Mtr4; Mtr4 helicase K12598 MTR4; ATP-dependent RNA helicase DOB1 [EC:5.6.2.6]
D Ski complex
E Dmel_CG10210 tst; twister, isoform B K12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6]
E Dmel_CG8777 CG8777; uncharacterized protein K12600 SKI3; superkiller protein 3
E Dmel_CG3909 CG3909; uncharacterized protein K12602 WDR61; WD repeat-containing protein 61
D Ccr4-NOT complex
E Dmel_CG31137 twin; twin, isoform C K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E Dmel_CG34407 Not1; Not1, isoform C K12604 CNOT1; CCR4-NOT transcription complex subunit 1
E Dmel_CG2161 Rga; regena, isoform A K12605 CNOT2; CCR4-NOT transcription complex subunit 2
E Dmel_CG15262 CG15262; uncharacterized protein K12605 CNOT2; CCR4-NOT transcription complex subunit 2
E Dmel_CG8426 Not3; CCR4-NOT transcription complex subunit 3, isoform B K12580 CNOT3; CCR4-NOT transcription complex subunit 3
E Dmel_CG31716 Cnot4; CCR4-NOT transcription complex subunit 4, isoform H K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]
E Dmel_CG5684 Pop2; Pop2, isoform D K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E Dmel_CG14213 Rcd-1; required for cell differentiation 1, isoform C K12606 RCD1; CCR4-NOT transcription complex subunit 9
E Dmel_CG9573 Rcd-1r; Rcd-1 related K12606 RCD1; CCR4-NOT transcription complex subunit 9
E Dmel_CG18616 Not10; CCR4-NOT transcription complex subunit 10, isoform B K12607 CNOT10; CCR4-NOT transcription complex subunit 10
D Pan complex
E Dmel_CG8232 PAN2; Poly(A)-binding protein-dependent poly(A) ribonuclease 2, isoform A K12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4]
E Dmel_CG11486 PAN3; Poly(A) specific ribonuclease subunit PAN3, isoform G K12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3
D Other 3'-5' decay factors
E Dmel_CG9323 Rhau; RHAU helicase, isoform B K14442 DHX36; ATP-dependent RNA helicase DHX36 [EC:5.6.2.6]
E Dmel_CG9214 Tob; transducer of ERBB2, isoform C K14443 TOB; protein Tob/BTG
E Dmel_CG31299 cu; curled, isoform D K18764 NOCT; nocturnin [EC:3.1.3.108]
E Dmel_CG44248 Snp; snipper, isoform D K18417 ERI2; ERI1 exoribonuclease 2 [EC:3.1.-.-]
E Dmel_CG2091 Dcps; decapping enzyme, scavenger K12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]
E Dmel_CG31759 CG31759; uncharacterized protein, isoform C K19612 PDE12; 2',5'-phosphodiesterase [EC:3.1.13.4 3.1.4.-]
E Dmel_CG9425 Helz; helicase with zinc finger, isoform C K25168 HELZ; helicase with zinc finger domain [EC:5.6.2.-]
E Dmel_CG5877 CG5877; uncharacterized protein, isoform D K26109 NRDE2; nuclear exosome regulator NRDE2
E Dmel_CG5263 smg; smaug, isoform E K27396 SMG; protein Smaug
E Dmel_CG3520 CG3520; uncharacterized protein K27498 FOCAD; focadhesin
C Other degradation factors
D RNases
E Dmel_CG10889 Regnase-1; regnase 1 K18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]
#
AProkaryotic type
B Bacterial mRNA degradation factors
C RNA degradosome components
D Ribonucreases
E Dmel_CG8730 drosha; drosha K03685 rnc; ribonuclease III [EC:3.1.26.3]
E Dmel_CG10214 CG10214; uncharacterized protein K13288 orn; oligoribonuclease [EC:3.1.-.-]
D Helicases
D Other RNA degradosome components
E Dmel_CG17654 Eno; enolase, isoform B K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
E Dmel_CG11337 PNPase; polynucleotide phosphorylase, isoform E K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
E Dmel_CG4001 Pfk; phosphofructokinase, isoform B K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
C Other RNA degradation factors
D Chaperones
E Dmel_CG8542 Hsc70-5; heat shock protein 70 cognate 5, isoform B K04043 dnaK; molecular chaperone DnaK
E Dmel_CG12101 Hsp60A; heat shock protein 60A, isoform A K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
E Dmel_CG7235 Hsp60C; heat shock protein 60C, isoform C K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
E Dmel_CG16954 Hsp60D; heat shock protein 60D, isoform A K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
E Dmel_CG2830 Hsp60B; heat shock protein 60B K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D Others
D Bacterial Small RNA Regulators
B Archeal mRNA degradation factors
C Exosome components
D Core exosome
E Dmel_CG3931 Rrp4; Rrp4, isoform B K03679 RRP4; exosome complex component RRP4
E Dmel_CG6249 Csl4; Csl4 K07573 CSL4; exosome complex component CSL4
D Cofactors
E Dmel_CG15481 Ski6; Ski6, isoform B K11600 RRP41; exosome complex component RRP41
E Dmel_CG8395 Rrp42; Rrp42 K12589 RRP42; exosome complex component RRP42
D Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: April 25, 2024