+D Chaperone KO
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Chaperones and Folding Catalysts - Drosophila melanogaster (fruit fly)
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AHeat shock proteins
B HSP110
C Dmel_CG6603 Hsp110; heat shock protein 110, isoform E K09485 HSP110; heat shock protein 110kDa
C Dmel_CG2918 Grp170; Grp170 co-chaperone, isoform B K09486 HYOU1; hypoxia up-regulated 1
B HSP100
C Dmel_CG4538 ClpX; caseinolytic protease chaperone subunit, isoform C K03544 clpX; ATP-dependent Clp protease ATP-binding subunit ClpX
B HSP90
C Dmel_CG1242 Hsp83; heat shock protein 83, isoform B K04079 HSP90A; molecular chaperone HtpG
C Dmel_CG5520 Gp93; glycoprotein 93 K09487 HSP90B; heat shock protein 90kDa beta
C Dmel_CG3152 Trap1; Trap1, isoform B K09488 TRAP1; TNF receptor-associated protein 1
B HSP70 / DNAK
C Dmel_CG4264 Hsc70-4; heat shock protein 70 cognate 4, isoform G K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
C Dmel_CG18743 Hsp70Ab; heat shock protein 70 Ab K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
C Dmel_CG31366 Hsp70Aa; heat shock protein 70 Aa K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
C Dmel_CG7756 Hsc70-2; heat shock protein 70 cognate 2 K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
C Dmel_CG5436 Hsp68; heat shock protein 68 K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
C Dmel_CG31359 Hsp70Bb; heat shock protein 70 Bb K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
C Dmel_CG5834 Hsp70Bbb; heat shock protein 70 Bbb K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
C Dmel_CG31449 Hsp70Ba; heat shock protein 70 Ba K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
C Dmel_CG6489 Hsp70Bc; heat shock protein 70 Bc K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
C Dmel_CG8937 Hsc70-1; heat shock protein 70 cognate 1, isoform A K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
C Dmel_CG4147 Hsc70-3; heat shock protein 70 cognate 3, isoform E K09490 HSPA5; endoplasmic reticulum chaperone BiP [EC:3.6.4.10]
C Dmel_CG8542 Hsc70-5; heat shock protein 70 cognate 5, isoform B K04043 dnaK; molecular chaperone DnaK
B HSP60 / Chaperonin
C Dmel_CG5374 CCT1; chaperonin containing TCP1 subunit 1, isoform A K09493 CCT1; T-complex protein 1 subunit alpha
C Dmel_CG7033 CCT2; chaperonin containing TCP1 subunit 2 K09494 CCT2; T-complex protein 1 subunit beta
C Dmel_CG8977 CCT3; chaperonin containing TCP1 subunit 3, isoform C K09495 CCT3; T-complex protein 1 subunit gamma
C Dmel_CG5525 CCT4; chaperonin containing TCP1 subunit 4 K09496 CCT4; T-complex protein 1 subunit delta
C Dmel_CG8439 CCT5; chaperonin containing TCP1 subunit 5, isoform A K09497 CCT5; T-complex protein 1 subunit epsilon
C Dmel_CG8231 CCT6; chaperonin containing TCP1 subunit 6 K09498 CCT6; T-complex protein 1 subunit zeta
C Dmel_CG8351 CCT7; chaperonin containing TCP1 subunit 7 K09499 CCT7; T-complex protein 1 subunit eta
C Dmel_CG8258 CCT8; chaperonin containing TCP1 subunit 8 K09500 CCT8; T-complex protein 1 subunit theta
C Dmel_CG12101 Hsp60A; heat shock protein 60A, isoform A K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
C Dmel_CG7235 Hsp60C; heat shock protein 60C, isoform C K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
C Dmel_CG16954 Hsp60D; heat shock protein 60D, isoform A K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
C Dmel_CG2830 Hsp60B; heat shock protein 60B K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
B HSP47
B HSP40 / DNAJ
C Dmel_CG8863 Droj2; DnaJ-like-2, isoform A K09502 DNAJA1; DnaJ homolog subfamily A member 1
C Dmel_CG9828 DnaJ-H; DnaJ homolog, isoform C K09503 DNAJA2; DnaJ homolog subfamily A member 2
C Dmel_CG5504 CG5504; uncharacterized protein, isoform B K09504 DNAJA3; DnaJ homolog subfamily A member 3
C Dmel_CG2790 CG2790; uncharacterized protein K09506 DNAJA5; DnaJ homolog subfamily A member 5
C Dmel_CG10578 DnaJ-1; DnaJ-like-1, isoform A K09510 DNAJB4; DnaJ homolog subfamily B member 4
C Dmel_CG2887 CG2887; uncharacterized protein K09510 DNAJB4; DnaJ homolog subfamily B member 4
C Dmel_CG5001 CG5001; uncharacterized protein, isoform B K09511 DNAJB5; DnaJ homolog subfamily B member 5
C Dmel_CG8448 mrj; mrj, isoform F K09512 DNAJB6; DnaJ homolog subfamily B member 6
C Dmel_CG4164 shv; shriveled K09517 DNAJB11; DnaJ homolog subfamily B member 11
C Dmel_CG3061 CG3061; uncharacterized protein K09518 DNAJB12; DnaJ homolog subfamily B member 12
C Dmel_CG30156 CG30156; uncharacterized protein, isoform B K09518 DNAJB12; DnaJ homolog subfamily B member 12
C Dmel_CG7556 CG7556; uncharacterized protein, isoform B K09521 DNAJC1; DnaJ homolog subfamily C member 1
C Dmel_CG10565 CG10565; uncharacterized protein, isoform B K09522 DNAJC2; DnaJ homolog subfamily C member 2
C Dmel_CG8286 P58IPK; P58IPK K09523 DNAJC3; DnaJ homolog subfamily C member 3
C Dmel_CG42567 DnaJ-60; DnaJ-like-60, isoform A K09524 DNAJC4; DnaJ homolog subfamily C member 4
C Dmel_CG6395 Csp; cysteine string protein, isoform F K09525 DNAJC5; DnaJ homolog subfamily C member 5
C Dmel_CG4599 Tpr2; tetratricopeptide repeat protein 2, isoform C K09527 DNAJC7; DnaJ homolog subfamily C member 7
C Dmel_CG10375 CG10375; uncharacterized protein, isoform B K09528 DNAJC8; DnaJ homolog subfamily C member 8
C Dmel_CG6693 CG6693; uncharacterized protein, isoform B K09529 DNAJC9; DnaJ homolog subfamily C member 9
C Dmel_CG8531 CG8531; uncharacterized protein K09531 DNAJC11; DnaJ homolog subfamily C member 11
C Dmel_CG2239 jdp; jdp, isoform A K09532 DNAJC12; DnaJ homolog subfamily C member 12
C Dmel_CG8014 Rme-8; receptor mediated endocytosis 8, isoform B K09533 DNAJC13; DnaJ homolog subfamily C member 13
C Dmel_CG14650 CG14650; uncharacterized protein K09534 DNAJC14; DnaJ homolog subfamily C member 14
C Dmel_CG40178 l(3)80Fg; lethal (3) 80Fg, isoform A K09536 DNAJC16; DnaJ homolog subfamily C member 16
C Dmel_CG17187 CG17187; uncharacterized protein K09537 DNAJC17; DnaJ homolog subfamily C member 17
C Dmel_CG7394 CG7394; uncharacterized protein, isoform C K09539 DNAJC19; DnaJ homolog subfamily C member 19
C Dmel_CG32727 CG32727; uncharacterized protein K09539 DNAJC19; DnaJ homolog subfamily C member 19
C Dmel_CG9089 wus; wurst, isoform B K19370 DNAJC22; DnaJ homolog subfamily C member 22
C Dmel_CG8583 Sec63; secretory 63 K09540 SEC63; translocation protein SEC63
C Dmel_CG7872 CG7872; uncharacterized protein K19371 DNAJC25; DnaJ homolog subfamily C member 25
C Dmel_CG43322 CG43322; uncharacterized protein K19373 DNAJC28; DnaJ homolog subfamily C member 28
C Dmel_CG11035 CG11035; uncharacterized protein, isoform B K19374 DNAJC30; DnaJ homolog subfamily C member 30
C Dmel_CG34246 Hsc20; heat shock protein cognate 20 K04082 hscB; molecular chaperone HscB
B HSP33
B HSP24
C Dmel_CG6155 Roe1; Roe1 K03687 GRPE; molecular chaperone GrpE
B HSP20
C Dmel_CG4533 l(2)efl; lethal (2) essential for life, isoform C K09542 CRYAB; crystallin, alpha B
B HSP15
B HSP10
C Dmel_CG11267 CG11267; uncharacterized protein K04078 groES; chaperonin GroES
C Dmel_CG9920 CG9920; uncharacterized protein K04078 groES; chaperonin GroES
B GimC
C Dmel_CG13993 Pfdn1; prefoldin 1, isoform B K09548 PFDN1; prefoldin subunit 1
C Dmel_CG6302 Pfdn2; prefoldin 2, isoform B K09549 PFDN2; prefoldin subunit 2
C Dmel_CG10635 Pfdn4; prefoldin 4 K09550 PFDN4; prefoldin subunit 4
C Dmel_CG7048 Pfdn5; prefoldin 5, isoform B K04797 pfdA; prefoldin alpha subunit
C Dmel_CG7770 Pfdn6; prefoldin 6, isoform B K04798 pfdB; prefoldin beta subunit
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AOther chaperones and cochaperones
B Calnexin / calreticulin
C Dmel_CG11958 Cnx99A; calnexin 99A, isoform E K08054 CANX; calnexin
C Dmel_CG9906 Cnx14D; calnexin 14D K08054 CANX; calnexin
C Dmel_CG1924 CG1924; uncharacterized protein K08054 CANX; calnexin
C Dmel_CG9429 Calr; calreticulin, isoform B K08057 CALR; calreticulin
B DegP / HtrA
C Dmel_CG8464 HtrA2; HTRA2-related serine protease, isoform B K08669 HTRA2; HtrA serine peptidase 2 [EC:3.4.21.108]
B AAA proteases
C Dmel_CG2658 Spg7; paraplegin, isoform A K09552 SPG7; spastic paraplegia 7 [EC:3.4.24.-]
C Dmel_CG6512 Afg3l2; AFG3 like matrix AAA peptidase subunit 2, isoform A K08956 AFG3; AFG3 family protein [EC:3.4.24.-]
B PapD
B SecB
B Sti1 / p60
C Dmel_CG2720 Stip1; stress induced phosphoprotein 1 K09553 STIP1; stress-induced-phosphoprotein 1
B Cdc37 / p50
C Dmel_CG12019 Cdc37; cell division cycle 37 K09554 CDC37; cell division cycle protein 37
B BAG
C Dmel_CG7945 CG7945; uncharacterized protein, isoform B K09556 BAG2; BCL2-associated athanogene 2
B Others
C Dmel_CG2947 HIP-R; Hsc/Hsp70-interacting protein related, isoform D K09560 ST13; suppressor of tumorigenicity protein 13
C Dmel_CG32789 HIP; Hsc/Hsp70-interacting protein K09560 ST13; suppressor of tumorigenicity protein 13
C Dmel_CG5203 STUB1; STIP1 homology and U-box containing protein 1 K09561 STUB1; STIP1 homology and U-box containing protein 1 [EC:2.3.2.27]
C Dmel_CG10973 CG10973; uncharacterized protein K09562 HSPBP1; hsp70-interacting protein
C Dmel_CG43320 HSPBAP1; HSPB1 associated protein 1 K19375 HSPBAP1; HSPB1-associated protein 1
C Dmel_CG13926 CG13926; uncharacterized protein K23327 HIKESHI; protein Hikeshi
C Dmel_CG6198 mora; morgana K16729 CHORDC1; cysteine and histidine-rich domain-containing protein
C Dmel_CG5013 CG5013; uncharacterized protein K23151 METTL23; methyltransferase-like protein 23 [EC:2.1.1.-]
C Dmel_CG2708 unc-45; uncoordinated 45, isoform B K21991 UNC45; protein unc-45
C Dmel_CG11577 CNPYb; canopy b K22816 CNPY3_4; protein canopy 3/4
C Dmel_CG3024 Torsin; torsin, isoform B K22990 TOR1; torsin-1
C Dmel_CG6378 SPARC; secreted protein, acidic, cysteine-rich, isoform B K24262 SPARC; secreted protein acidic and rich in cysteine
C Dmel_CG5094 Sgt; small glutamine-rich tetratricopeptide containing protein, isoform B K16365 SGTA; small glutamine-rich tetratricopeptide repeat-containing protein alpha
C Dmel_CG14894 Ttc1; tetratricopeptide repeat domain 1, isoform B K24926 TTC1; tetratricopeptide repeat protein 1
C Dmel_CG3189 Dpit47; DNA polymerase interacting tpr containing protein of 47kD, isoform B K24927 TTC4; tetratricopeptide repeat protein 4
C Dmel_CG17593 CG17593; uncharacterized protein, isoform B K24962 CCDC47; PAT complex subunit CCDC47
C Dmel_CG10674 CG10674; uncharacterized protein K24963 WDR83OS; PAT complex subunit Asterix
C Dmel_CG30498 boca; boca K25366 MESD; LRP chaperone MESD
C Dmel_CG30296 RIC-3; RIC3 acetylcholine receptor chaperone, isoform E K26164 RIC3; protein RIC-3
C Dmel_CG1416 CG1416; uncharacterized protein, isoform A K26216 AHSA1; activator of Hsp90 ATPase protein 1
C Dmel_CG13920 CG13920; uncharacterized protein, isoform C K26241 NACHO; novel acetylcholine receptor chaperone
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AIntramolecular chaperones
B Subtilisin family
C Dmel_CG7169 S1P; Site-1 protease K08653 MBTPS1; membrane-bound transcription factor site-1 protease [EC:3.4.21.112]
C Dmel_CG10772 Fur1; furin 1, isoform B K01349 FURIN; furin [EC:3.4.21.75]
C Dmel_CG18734 Fur2; furin 2, isoform D K01349 FURIN; furin [EC:3.4.21.75]
C Dmel_CG6438 amon; amontillado K01360 PCSK2; proprotein convertase subtilisin/kexin type 2 [EC:3.4.21.94]
C Dmel_CG3991 TppII; Tripeptidyl-peptidase II, isoform D K01280 TPP2; tripeptidyl-peptidase II [EC:3.4.14.10]
B Papain family
C Dmel_CG10992 CtsB; cathepsin B, isoform C K01363 CTSB; cathepsin B [EC:3.4.22.1]
C Dmel_CG4847 CtsK2; cathepsin K2, isoform A K01371 CTSK; cathepsin K [EC:3.4.22.38]
C Dmel_CG11459 CtsL3; cathepsin L3, isoform B K01365 CTSL; cathepsin L [EC:3.4.22.15]
C Dmel_CG6692 CtsL1; cathepsin L1, isoform C K01365 CTSL; cathepsin L [EC:3.4.22.15]
B Other peptidases
B Others
C Dmel_CG1787 Hexo2; hexosaminidase 2 K12373 HEXA_B; hexosaminidase [EC:3.2.1.52]
C Dmel_CG1318 Hexo1; hexosaminidase 1, isoform A K12373 HEXA_B; hexosaminidase [EC:3.2.1.52]
C Dmel_CG7002 Hml; hemolectin, isoform B K03900 VWF; von Willebrand factor
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AProtein folding catalysts
B Peptidyl prolyl isomerase
C Cyclophilin
D Dmel_CG2852 CG2852; uncharacterized protein, isoform A K03768 PPIB; peptidyl-prolyl cis-trans isomerase B (cyclophilin B) [EC:5.2.1.8]
D Dmel_CG3966 ninaA; neither inactivation nor afterpotential A K03768 PPIB; peptidyl-prolyl cis-trans isomerase B (cyclophilin B) [EC:5.2.1.8]
D Dmel_CG8336 Cyp40; cyclophilin 40, isoform D K05864 PPID; peptidyl-prolyl isomerase D [EC:5.2.1.8]
D Dmel_CG4886 cyp33; cyclophilin-33 K09564 PPIE; peptidyl-prolyl isomerase E (cyclophilin E) [EC:5.2.1.8]
D Dmel_CG9916 Cyp1; cyclophilin 1 K09565 PPIF; peptidyl-prolyl isomerase F (cyclophilin D) [EC:5.2.1.8]
D Dmel_CG7768 CG7768; uncharacterized protein, isoform B K09565 PPIF; peptidyl-prolyl isomerase F (cyclophilin D) [EC:5.2.1.8]
D Dmel_CG17266 CG17266; uncharacterized protein, isoform B K09567 PPIH; peptidyl-prolyl isomerase H (cyclophilin H) [EC:5.2.1.8]
D Dmel_CG13892 Cypl; Cyclophilin-like K12733 PPIL1; peptidyl-prolyl cis-trans isomerase-like 1 [EC:5.2.1.8]
D Dmel_CG7747 CG7747; uncharacterized protein K10598 PPIL2; peptidyl-prolyl cis-trans isomerase-like 2 [EC:5.2.1.8]
D Dmel_CG11777 CG11777; uncharacterized protein K12734 PPIL3; peptidyl-prolyl cis-trans isomerase-like 3 [EC:5.2.1.8]
D Dmel_CG5808 CG5808; uncharacterized protein K12735 PPIL4; peptidyl-prolyl cis-trans isomerase-like 4 [EC:5.2.1.8]
D Dmel_CG3511 CG3511; uncharacterized protein, isoform B K12736 PPWD1; peptidylprolyl isomerase domain and WD repeat-containing protein 1 [EC:5.2.1.8]
D Dmel_CG10907 CG10907; uncharacterized protein K12737 SDCCAG10; peptidyl-prolyl cis-trans isomerase SDCCAG10 [EC:5.2.1.8]
D Dmel_CG11856 Nup358; nucleoporin 358kD, isoform B K12172 RANBP2; E3 SUMO-protein ligase RanBP2 [EC:2.3.2.-]
C FKBP
D Dmel_CG11001 Fkbp12; FK506-binding protein 12kD K09568 FKBP1; FK506-binding protein 1 [EC:5.2.1.8]
D Dmel_CG14715 CG14715; uncharacterized protein K09569 FKBP2; FK506-binding protein 2 [EC:5.2.1.8]
D Dmel_CG4535 Fkbp59; FK506-binding protein 59kD, isoform B K09571 FKBP4_5; FK506-binding protein 4/5 [EC:5.2.1.8]
D Dmel_CG4735 shu; shutdown K09572 FKBP6; FK506-binding protein 6 [EC:5.2.1.8]
D Dmel_CG5482 zda; zonda, isoform B K09574 FKBP8; FK506-binding protein 8 [EC:5.2.1.8]
D Dmel_CG9847 Fkbp14; FK506-binding protein 14, isoform D K09577 FKBP14; FK506-binding protein 14 [EC:5.2.1.8]
D Dmel_CG17282 Bdbt; bride of doubletime K27238 BDBT; bride of doubletime
C Parvulin
D Dmel_CG17051 dod; dodo K09578 PIN1; peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 [EC:5.2.1.8]
D Dmel_CG11858 CG11858; uncharacterized protein K09579 PIN4; peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 [EC:5.2.1.8]
B Protein disulfide isomerase
C Dmel_CG31884 Trx2; thioredoxin 2, isoform A K03671 TXN; thioredoxin
C Dmel_CG8517 CG8517; uncharacterized protein K03671 TXN; thioredoxin
C Dmel_CG13473 CG13473; uncharacterized protein K03671 TXN; thioredoxin
C Dmel_CG3315 TrxT; thioredoxin T, isoform B K03671 TXN; thioredoxin
C Dmel_CG4193 dhd; deadhead, isoform B K03671 TXN; thioredoxin
C Dmel_CG8993 CG8993; uncharacterized protein K03671 TXN; thioredoxin
C Dmel_CG6852 Grx1; glutaredoxin 1, isoform C K03676 grxC; glutaredoxin 3
C Dmel_CG7975 Grx1t; glutaredoxin 1, testis-specific K03676 grxC; glutaredoxin 3
C Dmel_CG14407 Grx5; glutaredoxin 5 K07390 grxD; monothiol glutaredoxin
C Dmel_CG12206 CG12206; uncharacterized protein, isoform A K17479 GRXCR1; glutaredoxin domain-containing cysteine-rich protein 1
C Dmel_CG31559 CG31559; uncharacterized protein K17479 GRXCR1; glutaredoxin domain-containing cysteine-rich protein 1
C Dmel_CG6988 Pdi; protein disulfide isomerase, isoform E K09580 PDIA1; protein disulfide-isomerase A1 [EC:5.3.4.1]
C Dmel_CG8983 ERp60; endoplasmic reticulum p60 K08056 PDIA3; protein disulfide-isomerase A3 [EC:5.3.4.1]
C Dmel_CG9302 CG9302; uncharacterized protein K09583 PDIA5; protein disulfide-isomerase A5 [EC:5.3.4.1]
C Dmel_CG5809 CaBP1; calcium-binding protein 1, isoform B K09584 PDIA6; protein disulfide-isomerase A6 [EC:5.3.4.1]
C Dmel_CG1837 prtp; pretaporter, isoform B K13984 TXNDC5; thioredoxin domain-containing protein 5 [EC:5.3.4.1]
C Dmel_CG18132 CG18132; uncharacterized protein K13984 TXNDC5; thioredoxin domain-containing protein 5 [EC:5.3.4.1]
C Dmel_CG5027 Tmx3; Thioredoxin-related transmembrane protein 3 K09585 TMX3; protein disulfide-isomerase [EC:5.3.4.1]
C Dmel_CG11377 Creld; cysteine rich with EGF like domains, isoform B K24335 CRELD; protein disulfide-isomerase [EC:5.3.4.1]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: January 25, 2024