+F Repair protein KO
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DNA Repair and Recombination Proteins - Denitratisoma oestradiolicum
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D DENOEST_3610 Methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E DENOEST_0126 mutY; Adenine DNA glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E DENOEST_1687 nth; DNA glycosylase and apyrimidinic (AP) lyase (endonuclease III) K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D DENOEST_3699 Thiamine monophosphate synthase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D DENOEST_1023 dut; deoxyuridinetriphosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D DENOEST_3610 Methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E DENOEST_1363 putative phage SPO1 DNA polymerase-related protein, uracil-DNA glycosylase family K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E DENOEST_1717 Type-5 uracil-DNA glycosylase (modular protein) K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E DENOEST_0126 mutY; Adenine DNA glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E DENOEST_0990 tag; 3-methyl-adenine DNA glycosylase I, constitutive K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E DENOEST_3638 mutM; formamidopyrimidine/5-formyluracil/5-hydroxymethyluracil DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E DENOEST_1687 nth; DNA glycosylase and apyrimidinic (AP) lyase (endonuclease III) K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E DENOEST_0579 Exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E DENOEST_0587 xth; Exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D RecJ
E DENOEST_2232 recJ; ssDNA exonuclease, 5' --> 3'-specific K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E DENOEST_1007 ligA; DNA ligase, NAD(+)-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E DENOEST_3207 polA; fused DNA polymerase I 5'->3' exonuclease; 3'->5' polymerase; 3'->5' exonuclease K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E DENOEST_0190 uvrA; excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
E DENOEST_2132 uvrB; excinulease of nucleotide excision repair, DNA damage recognition component K03702 uvrB; excinuclease ABC subunit B
E DENOEST_1718 uvrC; excinuclease UvrABC, endonuclease subunit K03703 uvrC; excinuclease ABC subunit C
E DENOEST_1942 DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E DENOEST_2021 DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E DENOEST_3603 uvrD; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E DENOEST_3207 polA; fused DNA polymerase I 5'->3' exonuclease; 3'->5' polymerase; 3'->5' exonuclease K02335 polA; DNA polymerase I [EC:2.7.7.7]
E DENOEST_1007 ligA; DNA ligase, NAD(+)-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F DENOEST_3144 rpoB; DNA-directed RNA polymerase beta chain (Transcriptase beta chain) (RNA polymerase beta subunit) K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F DENOEST_3143 rpoC; DNA-directed RNA polymerase beta' chain (Transcriptase beta' chain) (RNA polymerase beta' subunit) K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F DENOEST_3112 rpoA; RNA polymerase, alpha subunit K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F DENOEST_3474 rpoZ; DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F DENOEST_0912 mfd; Transcription-repair-coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E DENOEST_2134 mutS; methyl-directed mismatch repair protein K03555 mutS; DNA mismatch repair protein MutS
D Molecular matchmaker
E DENOEST_1490 mutL; methyl-directed mismatch repair protein K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
D DNA exonucleases
E DENOEST_3230 xseA; Exodeoxyribonuclease 7 large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E DENOEST_0973 xseB; exonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E DENOEST_3595 dnaE; DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E DENOEST_3819 dnaN; DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E DENOEST_1451 DNA polymerase III subunit chi K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
E DENOEST_3608 DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E DENOEST_1733 holB; DNA-directed DNA polymerase III, delta subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E DENOEST_1350 DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E DENOEST_3259 Exonuclease RNase T and DNA polymerase III K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E DENOEST_1328 dnaX; DNA polymerase III subunit gamma/tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E DENOEST_1007 ligA; DNA ligase, NAD(+)-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E DENOEST_1942 DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E DENOEST_2021 DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E DENOEST_3603 uvrD; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E DENOEST_1853 Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E DENOEST_2019 Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E DENOEST_3613 ssb; Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E DENOEST_P0081 Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E DENOEST_P0177 protein of unknown function K03111 ssb; single-strand DNA-binding protein
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E DENOEST_1674 recB; RecBCD enzyme subunit RecB K03582 recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5]
E DENOEST_1673 recC; RecBCD enzyme subunit RecC K03583 recC; exodeoxyribonuclease V gamma subunit [EC:3.1.11.5]
E DENOEST_1675 recD; exonuclease V (RecBCD complex), alpha chain K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E DENOEST_3792 recA; DNA strand exchange and recombination protein with protease and nuclease activity K03553 recA; recombination protein RecA
E DENOEST_3420 ruvA; component of RuvABC resolvasome, regulatory subunit K03550 ruvA; holliday junction DNA helicase RuvA
E DENOEST_3422 ruvB; holliday junction helicase, subunit B K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E DENOEST_3417 ruvC; component of RuvABC resolvasome, endonuclease K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E DENOEST_3622 priA; Primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E DENOEST_0476 Primosomal replication protein N (fragment) K02686 priB; primosomal replication protein N
D RecFOR pathway proteins
E DENOEST_3792 recA; DNA strand exchange and recombination protein with protease and nuclease activity K03553 recA; recombination protein RecA
E DENOEST_2922 radA; repair protein radA homolog K04485 radA; DNA repair protein RadA/Sms
E DENOEST_0365 recG; ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E DENOEST_2232 recJ; ssDNA exonuclease, 5' --> 3'-specific K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E DENOEST_2191 recO; gap repair protein K03584 recO; DNA repair protein RecO (recombination protein O)
E DENOEST_1330 recR; gap repair protein K06187 recR; recombination protein RecR
E DENOEST_2341 recN; recombination and repair protein K03631 recN; DNA repair protein RecN (Recombination protein N)
E DENOEST_1739 rdgC; Recombination-associated protein RdgC K03554 rdgC; recombination associated protein RdgC
E DENOEST_3420 ruvA; component of RuvABC resolvasome, regulatory subunit K03550 ruvA; holliday junction DNA helicase RuvA
E DENOEST_3422 ruvB; holliday junction helicase, subunit B K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E DENOEST_3417 ruvC; component of RuvABC resolvasome, endonuclease K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
D Other HR factor
E DENOEST_0921 ygbT; conserved hypothetical protein K15342 cas1; CRISP-associated protein Cas1
D Archaeal homologous recombinant proteins
E DENOEST_3415 yjgR; putative ATPase K06915 herA; DNA double-strand break repair helicase HerA and related ATPase
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F DENOEST_2808 gyrA; DNA gyrase (type II topoisomerase), subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F DENOEST_3818 gyrB; DNA gyrase, subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
E Supressor
F DENOEST_1627 hupA; HU, DNA-binding transcriptional regulator, alpha subunit K03530 hupB; DNA-binding protein HU-beta
F DENOEST_1773 hupB; HU, DNA-binding transcriptional regulator, beta subunit K03530 hupB; DNA-binding protein HU-beta
F DENOEST_1902 hupB; DNA-binding protein HU-beta K03530 hupB; DNA-binding protein HU-beta
F DENOEST_2617 hupB; HU, DNA-binding transcriptional regulator, beta subunit K03530 hupB; DNA-binding protein HU-beta
F DENOEST_P0106 hupA; DNA-binding protein HU-alpha K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F DENOEST_1848 RecT protein K07455 recT; recombination protein RecT
F DENOEST_2015 RecT protein (fragment) K07455 recT; recombination protein RecT
F DENOEST_2232 recJ; ssDNA exonuclease, 5' --> 3'-specific K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F DENOEST_2191 recO; gap repair protein K03584 recO; DNA repair protein RecO (recombination protein O)
F DENOEST_1330 recR; gap repair protein K06187 recR; recombination protein RecR
F DENOEST_1007 ligA; DNA ligase, NAD(+)-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
F DENOEST_1613 protein of unknown function K03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein
F DENOEST_2855 putative Fis-like DNA-binding protein K03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein
F DENOEST_2997 himA; integration host factor (IHF), alpha subunit, DNA-binding protein, DNA replication K04764 ihfA; integration host factor subunit alpha
F DENOEST_3040 ihfB; integration host factor (IHF), DNA-binding protein, beta subunit K05788 ihfB; integration host factor subunit beta
E Supressor
F DENOEST_2356 recQ; ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F DENOEST_0190 uvrA; excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
F DENOEST_2132 uvrB; excinulease of nucleotide excision repair, DNA damage recognition component K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D DENOEST_1582 dbh; DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D DENOEST_1115 DNA polymerase V, subunit D (modular protein) K03503 umuD; DNA polymerase V [EC:3.4.21.-]
C Other SOS response factors
D DENOEST_3792 recA; DNA strand exchange and recombination protein with protease and nuclease activity K03553 recA; recombination protein RecA
D DENOEST_1116 LexA family transcriptional repressor K01356 lexA; repressor LexA [EC:3.4.21.88]
D DENOEST_2183 lexA; DNA-binding transcriptional repressor of SOS regulon K01356 lexA; repressor LexA [EC:3.4.21.88]
D DENOEST_2341 recN; recombination and repair protein K03631 recN; DNA repair protein RecN (Recombination protein N)
D DENOEST_1853 Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D DENOEST_2019 Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D DENOEST_3613 ssb; Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D DENOEST_P0081 Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D DENOEST_P0177 protein of unknown function K03111 ssb; single-strand DNA-binding protein
D DENOEST_3791 recX; Regulatory protein RecX K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D DENOEST_2869 rep; ATP-dependent DNA helicase Rep K03656 rep; ATP-dependent DNA helicase Rep [EC:5.6.2.4]
D DENOEST_0982 putative ATP-dependent DNA helicase HI_0387 K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
C Modulation of nucleotide pools
D DENOEST_3699 Thiamine monophosphate synthase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D DENOEST_1023 dut; deoxyuridinetriphosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D DENOEST_2277 Vitamin B12-dependent ribonucleotide reductase K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024