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Transfer RNA Biogenesis - Escherichia coli O6:K2:H1 CFT073 (UPEC)
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AEukaryotic type
B 5'processing factors
C Ribonucrease P
B 3'processing and CCA adding factors
C 3'processing factors
D c2812 elaC; Protein elaC K00784 rnz; ribonuclease Z [EC:3.1.26.11]
C CCA adding factors
D c3806 cca; tRNA nucleotidyltransferase K00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]
B tRNA spricing factors
C tRNA splicing endonuclease complex
C tRNA splicing ligase complex
D c4198 rtcB; Protein rtcB K14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]
C Other tRNA splicing factors
B tRNA transport factors
C tRNA export factors
C tRNA import factors
B Aminoacyl-tRNA synthetases (AARSs)
C Multi-aminoacyl-tRNA synthetase complex (MSC)
D c2936 gltX; Glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D c0235 proS; Prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D c0030 ileS; Isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D c0733 leuS; Leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D c2642 metG; Methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D c0766 glnS; Glutaminyl-tRNA synthetase K01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]
D c2291 argS; Arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D c3469 lysS; Lysyl-tRNA synthetase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D c5138 lysU; Lysyl-tRNA synthetase, heat inducible K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D c2280 aspS; Aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
C Other AARSs
D c1072 asnS; Asparaginyl-tRNA synthetase K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
D c2116 thrS; Threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D c1030 serS; Seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D c0642 cysS; Cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D c5358 valS; Valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D c3036 hisS; Histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D c2112 pheS; Phenylalanyl-tRNA synthetase alpha chain K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D c2029 tyrS; Tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D c4154 trpS; Tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
C Trans-editing factors
D c4834 yihZ; D-tyrosyl-tRNA(Tyr) deacylase K07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
C AARS associated factors
D c1376 ycfF; HIT-like protein ycfF K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
B tRNA modification factors
C Deaminases
C Dihydorouridine synthases
C Methylthiotransferase
C Methyltransferases
D c3547 yggH; Hypothetical methyltransferase yggH K03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]
D c0236 yaeB; Hypothetical protein yaeB K22900 TRMO; tRNA (adenine37-N6)-methyltransferase [EC:2.1.1.-]
C Psudouridine synthases
D c2863 truA; tRNA pseudouridine synthase A K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D c3922 truB; tRNA pseudouridine synthase B K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
D c3312 ygbO; Protein ygbO K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
C Thiolation factors
D c3056 yfhO; Cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
C KEOPS/EKC complex
C Elongator complex
C Elongator related proteins
C Other tRNA modification factors
D c4043 yrdC; Protein yrdC K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D c5255 miaA; tRNA delta(2)-isopentenylpyrophosphate transferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
D c4630 thdF; Probable tRNA modification GTPase trmE K03650 mnmE; tRNA modification GTPase [EC:3.6.-.-]
D c4669 gidA; Glucose inhibited division protein A K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
D c2167 selD; Selenide,water dikinase K01008 selD; selenide, water dikinase [EC:2.7.9.3]
B tRNA degradation factors
C TRAMP complex
C Rapid tRNA decay (RTD) pathway factors
D c5313 cysQ; CysQ protein K01082 cysQ; 3'(2'), 5'-bisphosphate nucleotidase [EC:3.1.3.7]
C Other tRNA degradation factors
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AProkaryotic type
B 5'processing factors
C Ribonucrease P
D c4628 rnpA; Ribonuclease P protein component K03536 rnpA; ribonuclease P protein component [EC:3.1.26.5]
B 3'processing and CCA adding factors
C 3'processing factors
D c2812 elaC; Protein elaC K00784 rnz; ribonuclease Z [EC:3.1.26.11]
D c2045 rnt; Ribonuclease T K03683 rnt; ribonuclease T [EC:3.1.13.-]
D c4467 rph; Ribonuclease PH K00989 rph; ribonuclease PH [EC:2.7.7.56]
D c0699 rna; Ribonuclease I precursor K01169 rna; ribonuclease I (enterobacter ribonuclease) [EC:4.6.1.21]
D c1757 rnb; Exoribonuclease II K01147 rnb; exoribonuclease II [EC:3.1.13.1]
D c2208 rnd; Ribonuclease D K03684 rnd; ribonuclease D [EC:3.1.13.5]
C CCA adding factors
D c3806 cca; tRNA nucleotidyltransferase K00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]
B tRNA spricing factors
C tRNA splicing endonucleases
C tRNA splicing ligases
D c4198 rtcB; Protein rtcB K14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]
C Other tRNA splicing factors
D c0180 yadP; 2'-5' RNA ligase K01975 thpR; RNA 2',3'-cyclic 3'-phosphodiesterase [EC:3.1.4.58]
B tRNA transport factors
C tRNA export factors
D c5478 yjjK; ABC transporter ATP-binding protein yjjK K06020 ettA; energy-dependent translational throttle protein EttA
B Aminoacyl-tRNA synthetases (AARSs)
C Multi-aminoacyl-tRNA synthetase complex (MSC)
D c0733 leuS; Leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D c0235 proS; Prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
C Other AARSs
D c2029 tyrS; Tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D c4154 trpS; Tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D c2116 thrS; Threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D c0030 ileS; Isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D c3469 lysS; Lysyl-tRNA synthetase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D c5138 lysU; Lysyl-tRNA synthetase, heat inducible K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D c5358 valS; Valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D c2642 metG; Methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D c1030 serS; Seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D c2280 aspS; Aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D c4379 glyQ; Glycyl-tRNA synthetase alpha chain K01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14]
D c4378 glyS; Glycyl-tRNA synthetase beta chain K01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14]
D c0642 cysS; Cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D c2936 gltX; Glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D c0766 glnS; Glutaminyl-tRNA synthetase K01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]
D c2291 argS; Arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D c2112 pheS; Phenylalanyl-tRNA synthetase alpha chain K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D c3036 hisS; Histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D c1072 asnS; Asparaginyl-tRNA synthetase K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
D c0177 yadB; Hypothetical protein yadB K01894 gluQ; glutamyl-Q tRNA(Asp) synthetase [EC:6.1.1.-]
C Trans-editing factors
D c4834 yihZ; D-tyrosyl-tRNA(Tyr) deacylase K07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
D c0601 ybaK; Protein ybaK K03976 ybaK; Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase [EC:3.1.1.-]
D c2192 yeaK; Hypothetical protein yeaK K19055 prdX; Ala-tRNA(Pro) deacylase [EC:3.1.1.-]
B tRNA modification factors
C Deaminases
D c3082 yfhC; Hypothetical protein yfhC K11991 tadA; tRNA(adenine34) deaminase [EC:3.5.4.33]
C Dihydorouridine synthases
D c5018 yjbN; Hypothetical protein yjbN K05539 dusA; tRNA-dihydrouridine synthase A [EC:1.-.-.-]
D c4026 yhdG; Hypothetical protein yhdG K05540 dusB; tRNA-dihydrouridine synthase B [EC:1.-.-.-]
D c2672 yohI; Hypothetical protein yohI K05541 dusC; tRNA-dihydrouridine synthase C [EC:1.-.-.-]
C Methylthiotransferases
D c0747 yleA; Hypothetical protein yleA K06168 miaB; tRNA-2-methylthio-N6-dimethylallyladenosine synthase [EC:2.8.4.3]
C Methyltransferases
D c2284 yecO; Protein yecO K15256 cmoA; tRNA (cmo5U34)-methyltransferase [EC:2.1.1.-]
D c2285 yecP; Hypothetical protein yecP K15257 cmoB; tRNA (mo5U34)-methyltransferase [EC:2.1.1.-]
D c1063 smtA; Protein smtA K06219 smtA; tRNA 5-carboxymethoxyuridine methyltransferase [EC:2.1.1.-]
D c5490 lasT; Hypothetical tRNA/rRNA methyltransferase lasT K02533 lasT; tRNA/rRNA methyltransferase [EC:2.1.1.-]
D c4928 trmA; tRNA (Uracil-5-)-methyltransferase K00557 trmA; tRNA (uracil-5-)-methyltransferase [EC:2.1.1.35]
D c3547 yggH; Hypothetical methyltransferase yggH K03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]
D c3128 trmD; tRNA (Guanine-N(1)-)-methyltransferase K00554 trmD; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]
D c4630 thdF; Probable tRNA modification GTPase trmE K03650 mnmE; tRNA modification GTPase [EC:3.6.-.-]
D c3106 yfiF; Hypothetical tRNA/rRNA methyltransferase yfiF K03214 yfiF; RNA methyltransferase, TrmH family [EC:2.1.1.-]
D c4476 spoU; tRNA (Guanosine-2'-O-)-methyltransferase K00556 trmH; tRNA (guanosine-2'-O-)-methyltransferase [EC:2.1.1.34]
D c3058 yfhQ; Hypothetical tRNA/rRNA methyltransferase yfhQ K15396 trmJ; tRNA (cytidine32/uridine32-2'-O)-methyltransferase [EC:2.1.1.200]
D c4428 yibK; Hypothetical tRNA/rRNA methyltransferase yibK K03216 trmL; tRNA (cytidine/uridine-2'-O-)-methyltransferase [EC:2.1.1.207]
D c0236 yaeB; Hypothetical protein yaeB K22900 TRMO; tRNA (adenine37-N6)-methyltransferase [EC:2.1.1.-]
D c3099 yfiC; Hypothetical protein yfiC K15460 yfiC; tRNA1Val (adenine37-N6)-methyltransferase [EC:2.1.1.223]
C Psudouridine synthases
D c2863 truA; tRNA pseudouridine synthase A K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D c3922 truB; tRNA pseudouridine synthase B K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
D c3357 yqcB; Hypothetical protein yqcB K06175 truC; tRNA pseudouridine65 synthase [EC:5.4.99.26]
D c3312 ygbO; Protein ygbO K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
D c0069 yabO; Ribosomal large subunit pseudouridine synthase A K06177 rluA; tRNA pseudouridine32 synthase / 23S rRNA pseudouridine746 synthase [EC:5.4.99.28 5.4.99.29]
C Thiolation factors
D c1512 ycfB; tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]
D c1818 ydaO; Hypothetical protein ydaO K14058 ttcA; tRNA 2-thiocytidine biosynthesis protein TtcA
D c4263 yhhP; SirA protein K04085 tusA; tRNA 2-thiouridine synthesizing protein A [EC:2.8.1.-]
D c4117 yheL; Hypothetical protein yheL K07237 tusB; tRNA 2-thiouridine synthesizing protein B
D c4118 yheM; Hypothetical protein yheM K07236 tusC; tRNA 2-thiouridine synthesizing protein C
D c4119 yheN; Hypothetical protein yheN K07235 tusD; tRNA 2-thiouridine synthesizing protein D [EC:2.8.1.-]
D c1107 yccK; Hypothetical protein yccK K11179 tusE; tRNA 2-thiouridine synthesizing protein E [EC:2.8.1.-]
D c3053 yfhF; Protein yfhF K13628 iscA; iron-sulfur cluster assembly protein
D c3056 yfhO; Cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D c3479 ygfZ; Unknown protein from 2D-page K06980 ygfZ; tRNA-modifying protein YgfZ
C KEOPS/EKC complex
C Other tRNA modification factors
D c4669 gidA; Glucose inhibited division protein A K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
D c5255 miaA; tRNA delta(2)-isopentenylpyrophosphate transferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
D c2870 yfcK; Hypothetical protein yfcK K15461 mnmC; tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein [EC:2.1.1.61 1.5.-.-]
D c0515 queA; S-adenosylmethionine:tRNA ribosyltransferase-isomerase K07568 queA; S-adenosylmethionine:tRNA ribosyltransferase-isomerase [EC:2.4.99.17]
D c0560 ybaX; Hypothetical protein ybaX K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20]
D c3324 ygcM; Putative 6-pyruvoyl tetrahydrobiopterin synthase K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]
D c3335 ygcF; Hypothetical protein ygcF K10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3]
D c3360 yqcD; Hypothetical protein yqcD K06879 queF; 7-cyano-7-deazaguanine reductase [EC:1.7.1.13]
D c5250 yjeS; Putative electron transport protein yjeS K18979 queG; epoxyqueuosine reductase [EC:1.17.99.6]
D c2167 selD; Selenide,water dikinase K01008 selD; selenide, water dikinase [EC:2.7.9.3]
D c0618 ybbB; Hypothetical protein ybbB K06917 selU; tRNA 2-selenouridine synthase [EC:2.9.1.3]
D c0516 tgt; Queuine tRNA-ribosyltransferase K00773 tgt; queuine tRNA-ribosyltransferase [EC:2.4.2.29]
D c0534 yajK; Thiamine biosynthesis protein thiI K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]
D c0226 mesJ; Putative cell cycle protein mesJ K04075 tilS; tRNA(Ile)-lysidine synthase [EC:6.3.4.19]
D c3002 ypfI; Hypothetical protein ypfI K06957 tmcA; tRNA(Met) cytidine acetyltransferase [EC:2.3.1.193]
D c2211 yeaZ; Hypothetical protease yeaZ K14742 tsaB; tRNA threonylcarbamoyladenosine biosynthesis protein TsaB
D c4043 yrdC; Protein yrdC K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D c3815 ygjD; Probable O-sialoglycoprotein endopeptidase K25706 tsaD; tRNA N6-adenosine threonylcarbamoyltransferase [EC:2.3.1.234]
D c5252 yjeE; Hypothetical protein yjeE K06925 tsaE; tRNA threonylcarbamoyladenosine biosynthesis protein TsaE
D c3383 ygdL; Hypothetical protein ygdL K22132 tcdA; tRNA threonylcarbamoyladenosine dehydratase
B tRNA degradation factors
C c5263 vacB; Ribonuclease R K12573 rnr; ribonuclease R [EC:3.1.13.1]
C c3920 pnp; Polyribonucleotide nucleotidyltransferase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: February 29, 2024