+D	AMR gene	KO
#<h2><a href="/kegg/brite.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; Antimicrobial Resistance Genes - Escherichia coli K-12 MG1655</h2>
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A<b>Gene variants</b>
B  beta-Lactamase genes
C    Class A [MT]
C    Class D [MT]
C    Class C [MT]
C    Class B [MT]
B  Aminoglycoside resistance genes
C    N-Acetyltransferases
C    Other acetyltransferases
C    O-Nucleotidyltransferases
C    O-Phosphotransferases
C    16S rRNA methyltransferases
B  Tetracycline resistance genes
C    Transporters
C    Others
B  Macrolide resistance genes
C    23S rRNA methyltransferases
C    Transporters
D      b0842 mdfA; multidrug efflux pump MdfA/Na(+):H(+) antiporter/K(+):H(+) antiporter	K08160 mdfA; MFS transporter, DHA1 family, multidrug/chloramphenicol efflux transport protein 
C    Others
B  Phenicol resistance genes
C    Transporters
C    Acetyltransferases
C    Phosphotransferase
C    23S rRNA methyltransferase
B  Sulfonamide resistance genes
C    Dihydropteroate synthase
B  Trimethoprim resistance genes
C    Dihydrofolate reductases
B  Quinolone resistance genes
C    Transporter
C    Other
B  Rifamycin resistance genes
C    ADP-ribosyl transferases
C    Oxygenases
B  Fosfomycin resistance genes
C    Transferases
C    Others
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A<b>Gene sets</b>
B  beta-Lactam resistance modules
C    Methicillin resistance [MD:M00625]
C    beta-Lactam resistance, Bla system [MD:M00627]
C    Imipenem resistance, repression of porin OprD [MD:M00745]
D      b0570 cusS; sensor histidine kinase CusS	K07644 cusS; two-component system, OmpR family, heavy metal sensor histidine kinase CusS [EC:2.7.13.3] 
D      b0571 cusR; DNA-binding transcriptional activator CusR	K07665 cusR; two-component system, OmpR family, copper resistance phosphate regulon response regulator CusR 
B  Vancomycin resistance modules
C    Vancomycin resistance, D-Ala-D-Lac type [MD:M00651]
D      b1488 ddpX; D-alanyl-D-alanine dipeptidase	K08641 vanX; zinc D-Ala-D-Ala dipeptidase [EC:3.4.13.22] 
C    Vancomycin resistance, D-Ala-D-Ser type [MD:M00652]
D      B  Tetracycline resistance
C    Tetracycline resistance, efflux pump Tet38 [MD:M00704]
B  CAMP resistance modules
C    Cationic antimicrobial peptide (CAMP) resistance, dltABCD operon [MD:M00725]
C    Cationic antimicrobial peptide (CAMP) resistance, lysyl-phosphatidylglycerol (L-PG) synthase MprF [MD:M00726]
C    Cationic antimicrobial peptide (CAMP) resistance, VraFG transporter [MD:M00730]
C    Cationic antimicrobial peptide (CAMP) resistance, protease PgtE [MD:M00744]
D      b1129 phoQ; sensor histidine kinase PhoQ	K07637 phoQ; two-component system, OmpR family, sensor histidine kinase PhoQ [EC:2.7.13.3] 
D      b1130 phoP; DNA-binding transcriptional dual regulator PhoP	K07660 phoP; two-component system, OmpR family, response regulator PhoP 
B  Multipdrug resistance modules
C    Multidrug resistance, efflux pump MexAB-OprM [MD:M00718]
D      b0463 acrA; multidrug efflux pump membrane fusion lipoprotein AcrA	K03585 acrA; membrane fusion protein, multidrug efflux system 
D      b0462 acrB; multidrug efflux pump RND permease AcrB	K18138 acrB; multidrug efflux pump 
C    Multidrug resistance, efflux pump MexCD-OprJ [MD:M00639]
C    Multidrug resistance, efflux pump MexEF-OprN [MD:M00641]
C    Multidrug resistance, efflux pump MexJK-OprM [MD:M00642]
C    Multidrug resistance, efflux pump MexXY-OprM [MD:M00643]
C    Multidrug resistance, efflux pump MexPQ-OpmE [MD:M00769]
D      b0487 cueR; DNA-binding transcriptional dual regulator CueR	K19591 cueR; MerR family transcriptional regulator, copper efflux regulator 
C    Multidrug resistance, efflux pump AdeABC [PATH:map01501] [MD:M00649]
C    Multidrug resistance, efflux pump AcrEF-TolC [MD:M00696]
D      b3264 envR; DNA-binding transcriptional repressor EnvR	K18140 envR; TetR/AcrR family transcriptional regulator, acrEF/envCD operon repressor 
D      b3265 acrE; multidrug efflux pump membrane fusion lipoprotein AcrE	K18141 acrE; membrane fusion protein, multidrug efflux system 
D      b3266 acrF; multidrug efflux pump RND permease AcrF	K18142 acrF; multidrug efflux pump 
D      b3035 tolC; outer membrane channel TolC	K12340 tolC; outer membrane protein 
C    Multidrug resistance, efflux pump MdtEF-TolC [MD:M00697]
D      b2369 evgA; DNA-binding transcriptional activator EvgA	K07690 evgA; two-component system, NarL family, response regulator EvgA 
D      b3513 mdtE; multidrug efflux pump membrane fusion protein MdtE	K18898 mdtE; membrane fusion protein, multidrug efflux system 
D      b3514 mdtF; multidrug efflux pump RND permease MdtF	K18899 mdtF; multidrug efflux pump 
D      b3035 tolC; outer membrane channel TolC	K12340 tolC; outer membrane protein 
C    Multidrug resistance, efflux pump BpeEF-OprC [MD:M00698]
C    Multidrug resistance, efflux pump AbcA [MD:M00700]
C    Multidrug resistance, efflux pump NorB [MD:M00702]
C    Multidrug resistance, efflux pump QacA [MD:M00714]
C    Multidrug resistance, efflux pump MepA [MD:M00705]
C    Multidrug resistance, repression of porin OmpF [MD:M00746]
D      b1531 marA; DNA-binding transcriptional dual regulator MarA	K13632 marA; AraC family transcriptional regulator, mar-sox-rob regulon activator 
D      b4439 micF; small regulatory RNA MicF	K18513 micF; small regulatory RNA MicF 
D      b0929 ompF; outer membrane porin F	K09476 ompF; outer membrane pore protein F 
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#Last updated: December 28, 2017