+D Chaperone KO
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Chaperones and Folding Catalysts - Escherichia fergusonii
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AHeat shock proteins
B HSP110
B HSP100
C EFER_1030 clpA; ATPase and specificity subunit of ClpA-ClpP ATP-dependent serine protease, chaperone activity K03694 clpA; ATP-dependent Clp protease ATP-binding subunit ClpA
C EFER_0475 clpB; protein disaggregation chaperone K03695 clpB; ATP-dependent Clp protease ATP-binding subunit ClpB
C EFER_2579 clpX; ATPase and specificity subunit of ClpX-ClpP ATP-dependent serine protease K03544 clpX; ATP-dependent Clp protease ATP-binding subunit ClpX
C EFER_3841 hslU; molecular chaperone and ATPase component of HslUV protease K03667 hslU; ATP-dependent HslUV protease ATP-binding subunit HslU
B HSP90
C EFER_2544 htpG; molecular chaperone HSP90 family K04079 HSP90A; molecular chaperone HtpG
C EFER_3880 htpG; Hsp90xo molecular chaperone K04079 HSP90A; molecular chaperone HtpG
B HSP70 / DNAK
C EFER_0010 dnaK; chaperone Hsp70, co-chaperone with DnaJ K04043 dnaK; molecular chaperone DnaK
C EFER_0646 hscA; DnaK-like molecular chaperone specific for IscU K04044 hscA; molecular chaperone HscA
C EFER_2453 hscC; Hsp70 family chaperone Hsc62, binds to RpoD and inhibits transcription K04045 hscC; molecular chaperone HscC
C EFER_2156 yegD; putative chaperone K04046 yegD; hypothetical chaperone protein
B HSP60 / Chaperonin
C EFER_4195 groL; Cpn60 chaperonin GroEL, large subunit of GroESL K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
B HSP47
B HSP40 / DNAJ
C EFER_0011 dnaJ; chaperone Hsp40, co-chaperone with DnaK K03686 dnaJ; molecular chaperone DnaJ
C EFER_1147 cbpA; curved DNA-binding protein, DnaJ homologue that functions as a co-chaperone of DnaK K05516 cbpA; curved DNA-binding protein
C EFER_0066 djlA; DnaJ-like protein, membrane anchored K05801 djlA; DnaJ like chaperone protein
C EFER_0645 hscB; DnaJ-like molecular chaperone specific for IscU K04082 hscB; molecular chaperone HscB
B HSP33
C EFER_3367 hslO; heat shock protein Hsp33 K04083 hslO; molecular chaperone Hsp33
B HSP24
C EFER_0459 grpE; heat shock protein HSP70 cofactor K03687 GRPE; molecular chaperone GrpE
B HSP20
C EFER_3982 ibpA; heat shock chaperone K04080 ibpA; molecular chaperone IbpA
C EFER_3981 ibpB; heat shock chaperone K04081 ibpB; molecular chaperone IbpB
B HSP15
C EFER_3366 hslR; ribosome-associated heat shock protein Hsp15 K04762 hslR; ribosome-associated heat shock protein Hsp15
B HSP10
C EFER_4194 groS; Cpn10 chaperonin GroES, small subunit of GroESL K04078 groES; chaperonin GroES
B GimC
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AOther chaperones and cochaperones
B Calnexin / calreticulin
B DegP / HtrA
C EFER_0184 degP; serine endoprotease (protease Do), membrane-associated K04771 degP; serine protease Do [EC:3.4.21.107]
B AAA proteases
C EFER_3155 ftsH; protease, ATP-dependent zinc-metallo K03798 ftsH; cell division protease FtsH [EC:3.4.24.-]
B PapD
C EFER_4037 atpB; F0 sector of membrane-bound ATP synthase, subunit a K02108 ATPF0A; F-type H+-transporting ATPase subunit a
C EFER_1137 conserved hypothetical protein K07346 fimC; fimbrial chaperone protein
C EFER_3403 putative fimbria chaperone protein precursor K07346 fimC; fimbrial chaperone protein
C EFER_3399 putative periplasmic pilin chaperone K07346 fimC; fimbrial chaperone protein
B SecB
C EFER_3603 secB; protein export chaperone K03071 secB; preprotein translocase subunit SecB
B Sti1 / p60
B Cdc37 / p50
B BAG
B Others
C EFER_3859 cpxP; periplasmic protein combats stress K06006 cpxP; periplasmic protein CpxP/Spy
C EFER_1323 spy; envelope stress induced periplasmic protein K06006 cpxP; periplasmic protein CpxP/Spy
C EFER_3752 zraP; Zn-binding periplasmic protein K07803 zraP; zinc resistance-associated protein
C EFER_3035 hdeA; stress response protein, acid-resistance protein K19777 hdeA; acid stress chaperone HdeA
C EFER_3034 hdeB; Protein hdeB precursor (10K-L protein) Periplasmic protein, repressed by H-NS K19778 hdeB; acid stress chaperone HdeB
C EFER_0351 hypA; protein involved in nickel insertion into hydrogenases 3 K04651 hypA; hydrogenase nickel incorporation protein HypA/HybF
C EFER_2934 hybF; protein involved with the maturation of hydrogenases 1 and 2 K04651 hypA; hydrogenase nickel incorporation protein HypA/HybF
C EFER_0350 hypB; GTP hydrolase involved in nickel liganding into hydrogenases K04652 hypB; hydrogenase nickel incorporation protein HypB
C EFER_1193 torD; chaperone involved in maturation of TorA subunit of trimethylamine N-oxide reductase system I K03533 torD; TorA specific chaperone
C EFER_4184 putative twin-argninine leader-binding protein for anaerobic dehydrogenase K23349 dmsD; putative dimethyl sulfoxide reductase chaperone
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AIntramolecular chaperones
B Subtilisin family
B Papain family
B Other peptidases
B Others
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AProtein folding catalysts
B Peptidyl prolyl isomerase
C Cyclophilin
D EFER_3336 ppiA; peptidyl-prolyl cis-trans isomerase A (rotamase A) K03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8]
D EFER_0567 ppiB; peptidyl-prolyl cis-trans isomerase B (rotamase B) K03768 PPIB; peptidyl-prolyl cis-trans isomerase B (cyclophilin B) [EC:5.2.1.8]
D EFER_2576 ppiD; peptidyl-prolyl cis-trans isomerase (rotamase D) K03770 ppiD; peptidyl-prolyl cis-trans isomerase D [EC:5.2.1.8]
C FKBP
D EFER_3317 fkpA; FKBP-type peptidyl-prolyl cis-trans isomerase (rotamase) K03772 fkpA; FKBP-type peptidyl-prolyl cis-trans isomerase FkpA [EC:5.2.1.8]
D EFER_4267 fklB; FKBP-type peptidyl-prolyl cis-trans isomerase (rotamase) K03773 fklB; FKBP-type peptidyl-prolyl cis-trans isomerase FklB [EC:5.2.1.8]
D EFER_0021 fkpB; FKBP-type peptidyl-prolyl cis-trans isomerase (rotamase) K03774 slpA; FKBP-type peptidyl-prolyl cis-trans isomerase SlpA [EC:5.2.1.8]
D EFER_3319 slyD; FKBP-type peptidyl prolyl cis-trans isomerase (rotamase) K03775 slyD; FKBP-type peptidyl-prolyl cis-trans isomerase SlyD [EC:5.2.1.8]
C Parvulin
D EFER_3727 ppiC; peptidyl-prolyl cis-trans isomerase C (rotamase C) K03769 ppiC; peptidyl-prolyl cis-trans isomerase C [EC:5.2.1.8]
D EFER_0064 surA; peptidyl-prolyl cis-trans isomerase (PPIase) K03771 surA; peptidyl-prolyl cis-trans isomerase SurA [EC:5.2.1.8]
B Protein disulfide isomerase
C EFER_3020 Putative thioredoxin (TRX) K03671 TXN; thioredoxin
C EFER_3723 trxA; thioredoxin 1 K03671 TXN; thioredoxin
C EFER_0491 trxC; thioredoxin 2 K03672 trxC; thioredoxin 2 [EC:1.8.1.8]
C EFER_0550 ybbN; putative thioredoxin domain-containing protein K05838 ybbN; putative thioredoxin
C EFER_3604 grxC; glutaredoxin 3 K03676 grxC; glutaredoxin 3
C EFER_1390 ydhD; monothiol glutaredoxin K07390 grxD; monothiol glutaredoxin
C EFER_3616 dsbA; periplasmic protein disulfide isomerase I K03673 dsbA; protein dithiol oxidoreductase (disulfide-forming) [EC:1.8.4.15]
C EFER_1770 dsbB; oxidoreductase that catalyzes reoxidation of DsbA protein disulfide isomerase I K03611 dsbB; protein dithiol:quinone oxidoreductase [EC:1.8.5.9]
C EFER_2828 dsbC; protein disulfide isomerase II K03981 dsbC; thiol:disulfide interchange protein DsbC [EC:5.3.4.1]
C EFER_4188 dipZ; fused thiol:disulfide interchange protein: activator of DsbC; conserved hypothetical protein K04084 dsbD; thioredoxin:protein disulfide reductase [EC:1.8.4.16]
C EFER_2285 ccmG; periplasmic thioredoxin of cytochrome c-type biogenesis K02199 ccmG; cytochrome c biogenesis protein CcmG, thiol:disulfide interchange protein DsbE
C EFER_2489 dsbG; periplasmic disulfide isomerase/thiol-disulphide oxidase K03805 dsbG; thiol:disulfide interchange protein DsbG
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: January 25, 2024