+D
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Transfer RNA Biogenesis - Escherichia coli W
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AEukaryotic type
B 5'processing factors
C Ribonucrease P
B 3'processing and CCA adding factors
C 3'processing factors
D WFL_12040 rbn; ribonuclease Z K00784 rnz; ribonuclease Z [EC:3.1.26.11]
C CCA adding factors
D WFL_16235 cca; multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase K00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]
B tRNA spricing factors
C tRNA splicing endonuclease complex
C tRNA splicing ligase complex
D WFL_17970 hypothetical protein K14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]
C Other tRNA splicing factors
B tRNA transport factors
C tRNA export factors
C tRNA import factors
B Aminoacyl-tRNA synthetases (AARSs)
C Multi-aminoacyl-tRNA synthetase complex (MSC)
D WFL_12900 gltX; glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D WFL_00945 proS; prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D WFL_00130 ileS; isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D WFL_03460 leuS; leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D WFL_11330 metG; methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D WFL_03600 glnS; glutaminyl-tRNA synthetase K01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]
D WFL_10070 argS; arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D WFL_21845 lysU; lysyl-tRNA synthetase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D WFL_15350 lysS; lysyl-tRNA synthetase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D WFL_10020 aspS; aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
C Other AARSs
D WFL_14125 alaS; alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D WFL_05065 asnS; asparaginyl-tRNA synthetase K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
D WFL_09245 thrS; threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D WFL_04875 serS; seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D WFL_02960 cysS; cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D WFL_22490 valS; valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D WFL_13415 hisS; histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D WFL_09225 pheS; phenylalanyl-tRNA synthetase subunit alpha K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D WFL_09220 pheT; phenylalanyl-tRNA synthetase subunit beta K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D WFL_08840 tyrS; tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D WFL_17775 trpS; tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
C Trans-editing factors
D WFL_20420 dtd; D-tyrosyl-tRNA(Tyr) deacylase K07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
C AARS associated factors
D WFL_05915 hinT; purine nucleoside phosphoramidase K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
B tRNA modification factors
C Deaminases
C Dihydorouridine synthases
C Methylthiotransferase
C Methyltransferases
D WFL_15725 trmI; tRNA (guanine-N(7)-)-methyltransferase K03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]
D WFL_00950 hypothetical protein K22900 TRMO; tRNA (adenine37-N6)-methyltransferase [EC:2.1.1.-]
C Psudouridine synthases
D WFL_12275 truA; tRNA pseudouridine synthase A K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D WFL_16820 truB; tRNA pseudouridine synthase B K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
D WFL_14410 truD; tRNA pseudouridine synthase D K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
C Thiolation factors
D WFL_13495 iscS; cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
C KEOPS/EKC complex
C Elongator complex
C Elongator related proteins
C Other tRNA modification factors
D WFL_17335 rimN; tRNA(ANN) t(6)A37 threonylcarbamoyladenosine modification protein K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D WFL_22045 miaA; tRNA delta(2)-isopentenylpyrophosphate transferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
D WFL_19580 mnmE; tRNA modification GTPase MnmE K03650 mnmE; tRNA modification GTPase [EC:3.6.-.-]
D WFL_19770 mnmG; tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnMG K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
D WFL_09485 selD; selenophosphate synthetase K01008 selD; selenide, water dikinase [EC:2.7.9.3]
B tRNA degradation factors
C TRAMP complex
C Rapid tRNA decay (RTD) pathway factors
D WFL_22275 cysQ; adenosine-3'(2'),5'-bisphosphate nucleotidase K01082 cysQ; 3'(2'), 5'-bisphosphate nucleotidase [EC:3.1.3.7]
C Other tRNA degradation factors
#
AProkaryotic type
B 5'processing factors
C Ribonucrease P
D WFL_19565 rnpA; ribonuclease P K03536 rnpA; ribonuclease P protein component [EC:3.1.26.5]
B 3'processing and CCA adding factors
C 3'processing factors
D WFL_12040 rbn; ribonuclease Z K00784 rnz; ribonuclease Z [EC:3.1.26.11]
D WFL_08915 rnt; ribonuclease T K03683 rnt; ribonuclease T [EC:3.1.13.-]
D WFL_19155 rph; ribonuclease PH K00989 rph; ribonuclease PH [EC:2.7.7.56]
D WFL_03310 rna; ribonuclease I K01169 rna; ribonuclease I (enterobacter ribonuclease) [EC:4.6.1.21]
D WFL_06735 rnb; exoribonuclease II K01147 rnb; exoribonuclease II [EC:3.1.13.1]
D WFL_09695 rnd; ribonuclease D K03684 rnd; ribonuclease D [EC:3.1.13.5]
C CCA adding factors
D WFL_16235 cca; multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase K00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]
B tRNA spricing factors
C tRNA splicing endonucleases
C tRNA splicing ligases
D WFL_17970 hypothetical protein K14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]
C Other tRNA splicing factors
D WFL_00710 ligT; 2'-5' RNA ligase K01975 thpR; RNA 2',3'-cyclic 3'-phosphodiesterase [EC:3.1.4.58]
D WFL_22840 kptA; RNA 2'-phosphotransferase K07559 kptA; putative RNA 2'-phosphotransferase [EC:2.7.1.-]
B tRNA transport factors
C tRNA export factors
D WFL_23150 yjjK; putative ABC transporter ATP-binding protein K06020 ettA; energy-dependent translational throttle protein EttA
B Aminoacyl-tRNA synthetases (AARSs)
C Multi-aminoacyl-tRNA synthetase complex (MSC)
D WFL_03460 leuS; leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D WFL_00945 proS; prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
C Other AARSs
D WFL_08840 tyrS; tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D WFL_17775 trpS; tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D WFL_09245 thrS; threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D WFL_00130 ileS; isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D WFL_21845 lysU; lysyl-tRNA synthetase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D WFL_15350 lysS; lysyl-tRNA synthetase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D WFL_14125 alaS; alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D WFL_22490 valS; valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D WFL_11330 metG; methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D WFL_04875 serS; seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D WFL_10020 aspS; aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D WFL_18715 glyQ; glycyl-tRNA synthetase subunit alpha K01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14]
D WFL_18710 glyS; glycyl-tRNA synthetase subunit beta K01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14]
D WFL_02960 cysS; cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D WFL_12900 gltX; glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D WFL_03600 glnS; glutaminyl-tRNA synthetase K01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]
D WFL_10070 argS; arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D WFL_09225 pheS; phenylalanyl-tRNA synthetase subunit alpha K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D WFL_09220 pheT; phenylalanyl-tRNA synthetase subunit beta K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D WFL_13415 hisS; histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D WFL_05065 asnS; asparaginyl-tRNA synthetase K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
D WFL_00695 yadB; glutamyl-Q tRNA(Asp) synthetase K01894 gluQ; glutamyl-Q tRNA(Asp) synthetase [EC:6.1.1.-]
C Trans-editing factors
D WFL_20420 dtd; D-tyrosyl-tRNA(Tyr) deacylase K07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
D WFL_02745 hypothetical protein K03976 ybaK; Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase [EC:3.1.1.-]
D WFL_09600 hypothetical protein K19055 prdX; Ala-tRNA(Pro) deacylase [EC:3.1.1.-]
B tRNA modification factors
C Deaminases
D WFL_13640 tadA; tRNA-specific adenosine deaminase K11991 tadA; tRNA(adenine34) deaminase [EC:3.5.4.33]
C Dihydorouridine synthases
D WFL_21465 dusA; tRNA-dihydrouridine synthase A K05539 dusA; tRNA-dihydrouridine synthase A [EC:1.-.-.-]
D WFL_17255 dusB; tRNA-dihydrouridine synthase B K05540 dusB; tRNA-dihydrouridine synthase B [EC:1.-.-.-]
D WFL_11450 dusC; tRNA-dihydrouridine synthase C K05541 dusC; tRNA-dihydrouridine synthase C [EC:1.-.-.-]
C Methylthiotransferases
D WFL_03560 miaB; (dimethylallyl)adenosine tRNA methylthiotransferase K06168 miaB; tRNA-2-methylthio-N6-dimethylallyladenosine synthase [EC:2.8.4.3]
C Methyltransferases
D WFL_10040 cmoA; tRNA cmo(5)U34 methyltransferase K15256 cmoA; tRNA (cmo5U34)-methyltransferase [EC:2.1.1.-]
D WFL_10045 cmoB; tRNA mo(5)U34 methyltransferase K15257 cmoB; tRNA (mo5U34)-methyltransferase [EC:2.1.1.-]
D WFL_05015 smtA; putative S-adenosyl-L-methionine-dependent methyltransferase K06219 smtA; tRNA 5-carboxymethoxyuridine methyltransferase [EC:2.1.1.-]
D WFL_23205 yjtD; putative RNA methyltransferase K02533 lasT; tRNA/rRNA methyltransferase [EC:2.1.1.-]
D WFL_21080 trmA; tRNA (uracil-5-)-methyltransferase K00557 trmA; tRNA (uracil-5-)-methyltransferase [EC:2.1.1.35]
D WFL_15725 trmI; tRNA (guanine-N(7)-)-methyltransferase K03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]
D WFL_13855 trmD; tRNA (guanine-N(1)-)-methyltransferase K00554 trmD; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]
D WFL_19580 mnmE; tRNA modification GTPase MnmE K03650 mnmE; tRNA modification GTPase [EC:3.6.-.-]
D WFL_13750 yfiF; putative methyltransferase K03214 yfiF; RNA methyltransferase, TrmH family [EC:2.1.1.-]
D WFL_19195 trmH; tRNA guanosine-2'-O-methyltransferase K00556 trmH; tRNA (guanosine-2'-O-)-methyltransferase [EC:2.1.1.34]
D WFL_13505 trmJ; tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ K15396 trmJ; tRNA (cytidine32/uridine32-2'-O)-methyltransferase [EC:2.1.1.200]
D WFL_18985 trmL; putative rRNA methylase K03216 trmL; tRNA (cytidine/uridine-2'-O-)-methyltransferase [EC:2.1.1.207]
D WFL_00950 hypothetical protein K22900 TRMO; tRNA (adenine37-N6)-methyltransferase [EC:2.1.1.-]
D WFL_13720 yfiC; putative S-adenosyl-L-methionine-dependent methyltransferase K15460 yfiC; tRNA1Val (adenine37-N6)-methyltransferase [EC:2.1.1.223]
C Psudouridine synthases
D WFL_12275 truA; tRNA pseudouridine synthase A K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D WFL_16820 truB; tRNA pseudouridine synthase B K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
D WFL_14655 truC; tRNA pseudouridine synthase C K06175 truC; tRNA pseudouridine65 synthase [EC:5.4.99.26]
D WFL_14410 truD; tRNA pseudouridine synthase D K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
D WFL_00280 rluA; 23S rRNA/tRNA pseudouridine synthase A K06177 rluA; tRNA pseudouridine32 synthase / 23S rRNA pseudouridine746 synthase [EC:5.4.99.28 5.4.99.29]
C Thiolation factors
D WFL_06065 mnmA; tRNA-specific 2-thiouridylase MnmA K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]
D WFL_07040 ttcA; tRNA 2-thiocytidine biosynthesis protein TtcA K14058 ttcA; tRNA 2-thiocytidine biosynthesis protein TtcA
D WFL_18225 sirA; sulfur transfer protein SirA K04085 tusA; tRNA 2-thiouridine synthesizing protein A [EC:2.8.1.-]
D WFL_17570 yheL; sulfur transfer complex subunit TusB K07237 tusB; tRNA 2-thiouridine synthesizing protein B
D WFL_17575 yheM; sulfur relay protein TusC K07236 tusC; tRNA 2-thiouridine synthesizing protein C
D WFL_17580 yheN; sulfur transfer complex subunit TusD K07235 tusD; tRNA 2-thiouridine synthesizing protein D [EC:2.8.1.-]
D WFL_05260 tusE; sulfur transfer protein TusE K11179 tusE; tRNA 2-thiouridine synthesizing protein E [EC:2.8.1.-]
D WFL_13485 iscA; iron-sulfur cluster assembly protein K13628 iscA; iron-sulfur cluster assembly protein
D WFL_13495 iscS; cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D WFL_15395 ygfZ; putative global regulator K06980 ygfZ; tRNA-modifying protein YgfZ
C KEOPS/EKC complex
C Other tRNA modification factors
D WFL_19770 mnmG; tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnMG K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
D WFL_22045 miaA; tRNA delta(2)-isopentenylpyrophosphate transferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
D WFL_12310 mnmC; bifunctional tRNA (mnm(5)s(2)U34)-methyltransferase/FAD-dependent cmnm(5)s(2)U34 oxidoreductase K15461 mnmC; tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein [EC:2.1.1.61 1.5.-.-]
D WFL_02340 queA; S-adenosylmethionine:tRNA ribosyltransferase-isomerase K07568 queA; S-adenosylmethionine:tRNA ribosyltransferase-isomerase [EC:2.4.99.17]
D WFL_02565 queC; queuosine biosynthesis protein QueC K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20]
D WFL_14515 sscR; putative 6-pyruvoyl tetrahydrobiopterin synthase K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]
D WFL_14570 hypothetical protein K10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3]
D WFL_14675 queF; 7-cyano-7-deazaguanine reductase K06879 queF; 7-cyano-7-deazaguanine reductase [EC:1.7.1.13]
D WFL_22020 yjeS; putative Fe-S electron transport protein K18979 queG; epoxyqueuosine reductase [EC:1.17.99.6]
D WFL_09485 selD; selenophosphate synthetase K01008 selD; selenide, water dikinase [EC:2.7.9.3]
D WFL_02850 selU; tRNA 2-selenouridine synthase K06917 selU; tRNA 2-selenouridine synthase [EC:2.9.1.3]
D WFL_02345 tgt; queuine tRNA-ribosyltransferase K00773 tgt; queuine tRNA-ribosyltransferase [EC:2.4.2.29]
D WFL_02435 thiI; tRNA s(4)U8 sulfurtransferase K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]
D WFL_00910 tilS; tRNA(Ile)-lysidine synthetase K04075 tilS; tRNA(Ile)-lysidine synthase [EC:6.3.4.19]
D WFL_13195 ypfI; putative hydrolase K06957 tmcA; tRNA(Met) cytidine acetyltransferase [EC:2.3.1.193]
D WFL_09710 yeaZ; putative peptidase K14742 tsaB; tRNA threonylcarbamoyladenosine biosynthesis protein TsaB
D WFL_17335 rimN; tRNA(ANN) t(6)A37 threonylcarbamoyladenosine modification protein K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D WFL_16280 gcp; glycation-binding protein, predicted protease/chaperone K25706 tsaD; tRNA N6-adenosine threonylcarbamoyltransferase [EC:2.3.1.234]
D WFL_22030 yjeE; ADP-binding protein K06925 tsaE; tRNA threonylcarbamoyladenosine biosynthesis protein TsaE
D WFL_14765 csdL; sulfur acceptor protein CsdL K22132 tcdA; tRNA threonylcarbamoyladenosine dehydratase
B tRNA degradation factors
C WFL_22085 rnr; exoribonuclease R K12573 rnr; ribonuclease R [EC:3.1.13.1]
C WFL_16810 pnp; polynucleotide phosphorylase/polyadenylase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
C WFL_13205 mvpA; plasmid maintenance protein K18828 mvpA; tRNA(fMet)-specific endonuclease VapC [EC:3.1.-.-]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: February 29, 2024