+E	Replication protein	KO
#<h2><a href="/kegg/brite.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; DNA Replication Proteins - Eubacterium siraeum V10Sc8a</h2>
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A<b>Eukaryotic type</b>
B  DNA Replication Initiation Factors
C    pre-RC (pre-replication complex)
C    CDK (cyclin dependent kinase)
C    DDK (Dbf-4 dependent kinase)
C    GINS complex
C    Other initiation factors
B  DNA Replication Elongation Factors
C    DNA polymerase alpha / primase complex
C    DNA polymerase epsilon complex
C    DNA polymerase delta complex
C    DNA polymerase gamma complex (mitochondrial)
C    RPA (replication protein A)
C    RFC (replication factor C)
C    RNase H
D      ES1_02770 RNase HI	K03469 rnhA; ribonuclease HI [EC:3.1.26.4] 
C    Other elongation factors
B  DNA Replication Termination Factors
C    DNA methylation enzymes
D      ES1_15320 Site-specific DNA methylase	K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] 
C    Prevention of re-replication factors
C    Telomere proteins
D      Shelterin complex
D      TERB1-TERB2-MAJIN complex
D      CST complex (animals)
D      CST complex (yeast)
D      RIF proteins
D      SIR proteins
C    Telomerase complex (animals)
D      Dyskerin complex
C    Telomerase complex (fungi)
D      Sm core complex
C    ELG1-RFC complex
C    MRN complex
C    Other termination factors
B  DNA Topoisomerases
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A<b>Prokaryotic type</b>
B  DNA Replication Initiation Factors
C    Initiation factors (bacterial)
D      ES1_19710 bacterial nucleoid protein Hbs	K03530 hupB; DNA-binding protein HU-beta 
D      ES1_26390 chromosomal replication initiator protein DnaA	K02313 dnaA; chromosomal replication initiator protein 
D      ES1_12550 primary replicative DNA helicase	K02314 dnaB; replicative DNA helicase [EC:5.6.2.3] 
D      ES1_15190 phage DNA replication protein (predicted replicative helicase loader)	K02315 dnaC; DNA replication protein DnaC 
D      ES1_16160 DNA replication protein	K02315 dnaC; DNA replication protein DnaC 
D      ES1_15890 DNA primase, catalytic core	K02316 dnaG; DNA primase [EC:2.7.7.101] 
D      ES1_18830 single stranded DNA-binding protein (ssb)	K03111 ssb; single-strand DNA-binding protein 
C    Initiation factors (archaeal)
B  DNA Replication Elongation Factors
C    Elongation factors (bacterial)
D      DNA polymerase III holoenzyme
E        ES1_22060 DNA polymerase III catalytic subunit, PolC type	K03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7] 
E        ES1_26400 DNA polymerase III, beta subunit	K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] 
E        ES1_20990 DNA polymerase III, delta subunit	K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] 
E        ES1_08940 hypothetical protein	K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7] 
E        ES1_25620 DNA polymerase III, subunits gamma and tau	K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] 
D      RNase H
E        ES1_02770 RNase HI	K03469 rnhA; ribonuclease HI [EC:3.1.26.4] 
D      Other elongation factors
E        ES1_08410 DNA polymerase I	K02335 polA; DNA polymerase I [EC:2.7.7.7] 
E        ES1_19960 DNA ligase, NAD-dependent	K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] 
C    Elongation factors (archaeal)
D      B-family DNA polymerases
D      D-family DNA polymerases
D      RNase H
E        ES1_02770 RNase HI	K03469 rnhA; ribonuclease HI [EC:3.1.26.4] 
D      RFC (replication factor C)
D      Other elongation factors
B  DNA Replication Termination Factors
C    Terminus site-binding protein
C    DNA methylation enzymes
D      ES1_12440 Site-specific DNA methylase	K06223 dam; DNA adenine methylase [EC:2.1.1.72] 
D      ES1_13040 Site-specific DNA methylase	K06223 dam; DNA adenine methylase [EC:2.1.1.72] 
C    Prevention of re-replication factors
B  DNA Topoisomerases
C    ES1_26500 DNA gyrase subunit A	K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2] 
C    ES1_26470 DNA gyrase subunit B	K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2] 
C    ES1_04430 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit	K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2] 
C    ES1_15040 DNA topoisomerase III, bacteria and conjugative plasmid	K03169 topB; DNA topoisomerase III [EC:5.6.2.1] 
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#Last updated: November 2, 2022