+C Kinase KO
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Protein Kinases - Felis catus (domestic cat)
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ASerine/threonine kinases: AGC group
B PKA family
C 101090494 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X3 K04345 PKA; protein kinase A [EC:2.7.11.11]
C 101095353 PRKACB; cAMP-dependent protein kinase catalytic subunit beta isoform X1 K04345 PKA; protein kinase A [EC:2.7.11.11]
C 111558780 PRKX; cAMP-dependent protein kinase catalytic subunit PRKX K19584 PRKX; protein kinase X [EC:2.7.11.11]
B PKG family
C 101097420 PRKG1; cGMP-dependent protein kinase 1 isoform X1 K07376 PRKG1; cGMP-dependent protein kinase 1 [EC:2.7.11.12]
C 101091618 PRKG2; cGMP-dependent protein kinase 2 isoform X1 K19477 PRKG2; cGMP-dependent protein kinase 2 [EC:2.7.11.12]
B PKC family [OT]
C 101086433 PRKCA; protein kinase C alpha type isoform X1 K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
C 101088970 PRKCB; protein kinase C beta type isoform X3 K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
C 101082196 PRKCG; protein kinase C gamma type isoform X1 K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
C 101087716 PRKCD; protein kinase C delta type K06068 PRKCD; novel protein kinase C delta type [EC:2.7.11.13]
C 101100958 PRKCE; protein kinase C epsilon type isoform X1 K18050 PRKCE; novel protein kinase C epsilon type [EC:2.7.11.13]
C 101082413 PRKCH; protein kinase C eta type isoform X1 K18051 PRKCH; novel protein kinase C eta type [EC:2.7.11.13]
C 101100730 PRKCQ; protein kinase C theta type isoform X2 K18052 PRKCQ; novel protein kinase C theta type [EC:2.7.11.13]
C 101087851 PRKCZ; protein kinase C zeta type isoform X3 K18952 PRKCZ; atypical protein kinase C zeta type [EC:2.7.11.13]
C 101087000 PRKCI; protein kinase C iota type isoform X1 K06069 PRKCI; atypical protein kinase C iota type [EC:2.7.11.13]
B PKN family
C 101097547 PKN1; serine/threonine-protein kinase N1 isoform X2 K06071 PKN1; serine/threonine-protein kinase N1 [EC:2.7.11.13]
C 101081653 PKN2; serine/threonine-protein kinase N2 isoform X1 K23691 PKN2; serine/threonine-protein kinase N2 [EC:2.7.11.13]
C 101093557 PKN3; serine/threonine-protein kinase N3 isoform X7 K23692 PKN3; serine/threonine-protein kinase N3 [EC:2.7.11.13]
B AUR family [OT]
C 101091184 AURKA; aurora kinase A K11481 AURKA; aurora kinase A [EC:2.7.11.1]
C 101081264 AURKB; aurora kinase B isoform X1 K11479 AURKB; aurora kinase B [EC:2.7.11.1]
C 102899963 AURKC; aurora kinase C isoform X2 K11480 AURKC; aurora kinase C [EC:2.7.11.1]
C 101096595 aurora kinase C-like K11480 AURKC; aurora kinase C [EC:2.7.11.1]
B PDK1 family
C 101101686 PDPK1; 3-phosphoinositide-dependent protein kinase 1 isoform X3 K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
B AKT/PKB family
C 101087931 AKT1; RAC-alpha serine/threonine-protein kinase K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
C 101092818 AKT3; RAC-gamma serine/threonine-protein kinase isoform X4 K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
C 100499544 AKT2; RAC-beta serine/threonine-protein kinase isoform X4 K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
B SGK family [OT]
C 101098954 SGK1; serine/threonine-protein kinase Sgk1 isoform X4 K13302 SGK1; serum/glucocorticoid-regulated kinase 1 [EC:2.7.11.1]
C 101095733 SGK2; serine/threonine-protein kinase Sgk2 isoform X1 K13303 SGK2; serum/glucocorticoid-regulated kinase 2 [EC:2.7.11.1]
C 101095636 SGK3; serine/threonine-protein kinase Sgk3 isoform X1 K13304 SGK3; serum/glucocorticoid-regulated kinase 3 [EC:2.7.11.1]
B RSK family [OT]
C 101082546 RPS6KA3; ribosomal protein S6 kinase alpha-3 isoform X1 K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
C 101086492 RPS6KA1; ribosomal protein S6 kinase alpha-1 isoform X2 K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
C 101099466 RPS6KA2; ribosomal protein S6 kinase alpha-2 isoform X1 K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
C 101094163 RPS6KA6; ribosomal protein S6 kinase alpha-6 isoform X1 K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
C 101093713 RPS6KA4; ribosomal protein S6 kinase alpha-4 isoform X1 K16510 RPS6KA4; ribosomal protein S6 kinase alpha-4 [EC:2.7.11.1]
C 101095179 RPS6KA5; LOW QUALITY PROTEIN: ribosomal protein S6 kinase alpha-5 K04445 RPS6KA5; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
C 101091812 RPS6KB2; ribosomal protein S6 kinase beta-2 isoform X3 K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
C 101092561 RPS6KB1; ribosomal protein S6 kinase beta-1 isoform X2 K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
C 101082459 RPS6KC1; ribosomal protein S6 kinase delta-1 isoform X4 K20839 RSKL; ribosomal protein S6 kinase-like
C 101095665 RPS6KL1; ribosomal protein S6 kinase-like 1 isoform X1 K20839 RSKL; ribosomal protein S6 kinase-like
B NDR family
C 101081905 STK38L; serine/threonine-protein kinase 38-like isoform X1 K08790 STK38; serine/threonine kinase 38 [EC:2.7.11.1]
C 101080969 STK38; serine/threonine-protein kinase 38 K08790 STK38; serine/threonine kinase 38 [EC:2.7.11.1]
C 101081470 LATS1; serine/threonine-protein kinase LATS1 isoform X1 K08791 LATS1_2; serine/threonine-protein kinase LATS1/2 [EC:2.7.11.1]
C 101093824 LATS2; serine/threonine-protein kinase LATS2 isoform X1 K08791 LATS1_2; serine/threonine-protein kinase LATS1/2 [EC:2.7.11.1]
B MAST family [OT]
C 101081744 MAST2; microtubule-associated serine/threonine-protein kinase 2 isoform X1 K08789 MAST; MAST-subfamily protein kinase [EC:2.7.11.37]
C 101087553 MAST4; microtubule-associated serine/threonine-protein kinase 4 isoform X1 K08789 MAST; MAST-subfamily protein kinase [EC:2.7.11.37]
C 101093084 MAST1; microtubule-associated serine/threonine-protein kinase 1 isoform X5 K08789 MAST; MAST-subfamily protein kinase [EC:2.7.11.37]
C 101093339 MAST3; microtubule-associated serine/threonine-protein kinase 3 isoform X19 K08789 MAST; MAST-subfamily protein kinase [EC:2.7.11.37]
C 101083601 MASTL; serine/threonine-protein kinase greatwall isoform X1 K16309 MASTL; serine/threonine-protein kinase greatwall [EC:2.7.11.36]
B YANK family
C 101084680 STK32A; serine/threonine-protein kinase 32A isoform X1 K08793 STK32; serine/threonine kinase 32 [EC:2.7.11.1]
C 101086850 STK32C; serine/threonine-protein kinase 32C isoform X3 K08793 STK32; serine/threonine kinase 32 [EC:2.7.11.1]
C 101100302 STK32B; serine/threonine-protein kinase 32B isoform X2 K08793 STK32; serine/threonine kinase 32 [EC:2.7.11.1]
B DMPK family [OT]
C 101081940 DMPK; myotonin-protein kinase isoform X1 K08788 DMPK; dystrophia myotonica-protein kinase [EC:2.7.11.1]
C 101092552 ROCK1; rho-associated protein kinase 1 isoform X1 K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
C 101094501 ROCK2; rho-associated protein kinase 2 isoform X1 K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
C 101084370 CDC42BPB; serine/threonine-protein kinase MRCK beta K16307 CDC42BP; serine/threonine-protein kinase MRCK [EC:2.7.11.1]
C 101088047 CDC42BPA; serine/threonine-protein kinase MRCK alpha isoform X3 K16307 CDC42BP; serine/threonine-protein kinase MRCK [EC:2.7.11.1]
C 101094954 CDC42BPG; serine/threonine-protein kinase MRCK gamma isoform X9 K16307 CDC42BP; serine/threonine-protein kinase MRCK [EC:2.7.11.1]
C 101094297 CIT; citron Rho-interacting kinase isoform X9 K16308 CIT; citron Rho-interacting kinase [EC:2.7.11.35]
B GRK family [OT]
C 101089290 GRK7; rhodopsin kinase GRK7 isoform X1 K00909 GRK1_7; rhodopsin kinase [EC:2.7.11.14]
C 101092327 GRK1; rhodopsin kinase GRK1 K00909 GRK1_7; rhodopsin kinase [EC:2.7.11.14]
C 101090393 GRK3; beta-adrenergic receptor kinase 2 isoform X4 K00910 ADRBK; beta-adrenergic-receptor kinase [EC:2.7.11.15]
C 101101082 GRK2; beta-adrenergic receptor kinase 1 isoform X1 K00910 ADRBK; beta-adrenergic-receptor kinase [EC:2.7.11.15]
C 101089047 GRK5; G protein-coupled receptor kinase 5 isoform X1 K08291 GRK4_5_6; G protein-coupled receptor kinase [EC:2.7.11.16]
C 101086226 GRK4; G protein-coupled receptor kinase 4 isoform X1 K08291 GRK4_5_6; G protein-coupled receptor kinase [EC:2.7.11.16]
C 101087379 GRK6; G protein-coupled receptor kinase 6 isoform X1 K08291 GRK4_5_6; G protein-coupled receptor kinase [EC:2.7.11.16]
B Other
C 101085585 RSKR; ribosomal protein S6 kinase-related protein isoform X2 K17529 SGK494; uncharacterized serine/threonine-protein kinase SgK494 [EC:2.7.11.1]
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ASerine/threonine kinases: CAMK group
B CAMK1 family [OT]
C 101084178 CAMK1; calcium/calmodulin-dependent protein kinase type 1 isoform X6 K08794 CAMK1; calcium/calmodulin-dependent protein kinase I [EC:2.7.11.17]
C 101089070 CAMK1G; calcium/calmodulin-dependent protein kinase type 1G isoform X2 K08794 CAMK1; calcium/calmodulin-dependent protein kinase I [EC:2.7.11.17]
C 101097250 CAMK1D; calcium/calmodulin-dependent protein kinase type 1D isoform X3 K08794 CAMK1; calcium/calmodulin-dependent protein kinase I [EC:2.7.11.17]
C 101095400 CAMK4; calcium/calmodulin-dependent protein kinase type IV K05869 CAMK4; calcium/calmodulin-dependent protein kinase IV [EC:2.7.11.17]
C 101087718 PNCK; calcium/calmodulin-dependent protein kinase type 1B isoform X1 K08795 PNCK; pregnancy upregulated non-ubiquitously expressed CaM kinase [EC:2.7.11.17]
C 101089588 CAMKV; caM kinase-like vesicle-associated protein isoform X1 K08812 CAMKV; CaM kinase-like vesicle-associated [EC:2.7.11.-]
B CAMK2 family
C 101098221 CAMK2D; calcium/calmodulin-dependent protein kinase type II subunit delta isoform X4 K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
C 101098090 CAMK2G; calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X1 K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
C 101084342 CAMK2A; calcium/calmodulin-dependent protein kinase type II subunit alpha isoform X1 K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
C 101098615 CAMK2B; calcium/calmodulin-dependent protein kinase type II subunit beta isoform X2 K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
B CAMKL family
C 101096106 BRSK2; serine/threonine-protein kinase BRSK2 isoform X1 K08796 BRSK; BR serine/threonine kinase [EC:2.7.11.1]
C 101091827 BRSK1; serine/threonine-protein kinase BRSK1 isoform X1 K08796 BRSK; BR serine/threonine kinase [EC:2.7.11.1]
C 101083365 CHEK1; serine/threonine-protein kinase Chk1 K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
C 101094041 HUNK; hormonally up-regulated neu tumor-associated kinase isoform X1 K08797 HUNK; hormonally upregulated Neu-associated kinase [EC:2.7.11.1]
C 101095375 MARK2; serine/threonine-protein kinase MARK2 isoform X2 K08798 MARK; MAP/microtubule affinity-regulating kinase [EC:2.7.11.1]
C 101084500 MARK4; MAP/microtubule affinity-regulating kinase 4 isoform X1 K08798 MARK; MAP/microtubule affinity-regulating kinase [EC:2.7.11.1]
C 101099270 MARK1; serine/threonine-protein kinase MARK1 isoform X1 K08798 MARK; MAP/microtubule affinity-regulating kinase [EC:2.7.11.1]
C 101085385 MARK3; MAP/microtubule affinity-regulating kinase 3 isoform X8 K08798 MARK; MAP/microtubule affinity-regulating kinase [EC:2.7.11.1]
C 101099597 MELK; maternal embryonic leucine zipper kinase isoform X1 K08799 MELK; maternal embryonic leucine zipper kinase [EC:2.7.11.1]
C 101092240 NIM1K; serine/threonine-protein kinase NIM1 K16310 NIM1; serine/threonine-protein kinase NIM1 [EC:2.7.11.1]
C 101084766 NUAK2; NUAK family SNF1-like kinase 2 isoform X2 K08800 NUAK; NUAK family, SNF1-like kinase [EC:2.7.11.1]
C 101089625 NUAK1; NUAK family SNF1-like kinase 1 K08800 NUAK; NUAK family, SNF1-like kinase [EC:2.7.11.1]
C 101096339 PASK; PAS domain-containing serine/threonine-protein kinase isoform X1 K08801 PASK; PAS domain containing serine/threonine kinase [EC:2.7.11.1]
C 101096000 PRKAA2; 5'-AMP-activated protein kinase catalytic subunit alpha-2 isoform X1 K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
C 101095885 PRKAA1; 5'-AMP-activated protein kinase catalytic subunit alpha-1 isoform X3 K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
C 101092782 SIK1; serine/threonine-protein kinase SIK1 K19008 SIK1; serine/threonine-protein kinase SIK1 [EC:2.7.11.1]
C 101091894 SIK2; serine/threonine-protein kinase SIK2 isoform X1 K16311 SIK2; serine/threonine-protein kinase SIK2 [EC:2.7.11.1]
C 101081328 SIK3; serine/threonine-protein kinase SIK3 isoform X1 K19009 SIK3; serine/threonine-protein kinase SIK3 [EC:2.7.11.1]
C 101098003 SNRK; SNF-related serine/threonine-protein kinase isoform X1 K08802 SNRK; SNF related kinase [EC:2.7.11.1]
C 101085024 STK11; serine/threonine-protein kinase STK11 isoform X2 K07298 STK11; serine/threonine-protein kinase 11 [EC:2.7.11.1]
B DAPK family
C 101099780 DAPK3; death-associated protein kinase 3 K08803 DAPK; death-associated protein kinase [EC:2.7.11.1]
C 101089774 DAPK2; death-associated protein kinase 2 isoform X1 K08803 DAPK; death-associated protein kinase [EC:2.7.11.1]
C 101084322 DAPK1; death-associated protein kinase 1 isoform X1 K08803 DAPK; death-associated protein kinase [EC:2.7.11.1]
C 101086995 STK17B; serine/threonine-protein kinase 17B K08804 STK17; serine/threonine kinase 17 [EC:2.7.11.1]
C 101089252 STK17A; serine/threonine-protein kinase 17A isoform X2 K08804 STK17; serine/threonine kinase 17 [EC:2.7.11.1]
B DCAMKL family
C 101093682 DCLK2; serine/threonine-protein kinase DCLK2 isoform X1 K08805 DCLK1_2; doublecortin-like kinase 1/2 [EC:2.7.11.1]
C 101083643 DCLK1; serine/threonine-protein kinase DCLK1 isoform X5 K08805 DCLK1_2; doublecortin-like kinase 1/2 [EC:2.7.11.1]
C 101091806 DCLK3; serine/threonine-protein kinase DCLK3 K17530 DCLK3; doublecortin-like kinase 3 [EC:2.7.11.1]
B MAPKAPK family [OT]
C 101090833 MAPKAPK2; MAP kinase-activated protein kinase 2 isoform X1 K04443 MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2 [EC:2.7.11.1]
C 101096794 MAPKAPK3; MAP kinase-activated protein kinase 3 isoform X2 K04444 MAPKAPK3; mitogen-activated protein kinase-activated protein kinase 3 [EC:2.7.11.1]
C 101082699 MAPKAPK5; MAP kinase-activated protein kinase 5 isoform X5 K04442 MAPKAPK5; mitogen-activated protein kinase-activated protein kinase 5 [EC:2.7.11.1]
C 101087206 MKNK2; MAP kinase-interacting serine/threonine-protein kinase 2 isoform X1 K04372 MKNK; MAP kinase interacting serine/threonine kinase [EC:2.7.11.1]
C 101082505 MKNK1; MAP kinase-interacting serine/threonine-protein kinase 1 isoform X5 K04372 MKNK; MAP kinase interacting serine/threonine kinase [EC:2.7.11.1]
B MLCK family
C 101088408 MYLK4; myosin light chain kinase family member 4 isoform X1 K00907 MYLK; myosin-light-chain kinase [EC:2.7.11.18]
C 101091744 MYLK3; myosin light chain kinase 3 isoform X1 K00907 MYLK; myosin-light-chain kinase [EC:2.7.11.18]
C 101095813 MYLK2; myosin light chain kinase 2, skeletal/cardiac muscle K00907 MYLK; myosin-light-chain kinase [EC:2.7.11.18]
C 101080315 TTN; titin isoform X1 K12567 TTN; titin [EC:2.7.11.1]
B PHK family
C 101081184 PHKG1; phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform K00871 PHKG; phosphorylase kinase gamma subunit [EC:2.7.11.19]
C 101092572 PHKG2; phosphorylase b kinase gamma catalytic chain, liver/testis isoform isoform X1 K00871 PHKG; phosphorylase kinase gamma subunit [EC:2.7.11.19]
B PIM family [OT]
C 493888 PIM1; serine/threonine-protein kinase pim-1 K04702 PIM1; proto-oncogene serine/threonine-protein kinase Pim-1 [EC:2.7.11.1]
C 101098037 PIM2; serine/threonine-protein kinase pim-2 K08806 PIM2; proto-oncogene serine/threonine-protein kinase Pim-2 [EC:2.7.11.1]
C 101100064 PIM3; serine/threonine-protein kinase pim-3 K08807 PIM3; proto-oncogene serine/threonine-protein kinase Pim-3 [EC:2.7.11.1]
B PKD family
C 101100883 PRKD3; serine/threonine-protein kinase D3 K06070 PKD; protein kinase D [EC:2.7.11.13]
C 101100101 PRKD2; serine/threonine-protein kinase D2 isoform X1 K06070 PKD; protein kinase D [EC:2.7.11.13]
C 101080543 PRKD1; serine/threonine-protein kinase D1 isoform X1 K06070 PKD; protein kinase D [EC:2.7.11.13]
B PSK family
C 101081942 PSKH1; serine/threonine-protein kinase H1 isoform X2 K08808 PSKH; protein serine kinase H [EC:2.7.11.1]
C 101095152 PSKH2; serine/threonine-protein kinase H2 K08808 PSKH; protein serine kinase H [EC:2.7.11.1]
B RAD53 family
C 101085665 CHEK2; serine/threonine-protein kinase Chk2 isoform X3 K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
B Trio family [OT]
C 101101154 SPEG; striated muscle preferentially expressed protein kinase isoform X2 K08809 SPEG; striated muscle-specific serine/threonine protein kinase [EC:2.7.11.1]
C 101091173 TRIO; triple functional domain protein isoform X1 K08810 TRIO; triple functional domain protein [EC:2.7.11.1]
C 101094783 KALRN; kalirin isoform X26 K15048 KALRN; kalirin [EC:2.7.11.1]
C 101101539 OBSCN; obscurin isoform X1 K17531 OBSCN; obscurin-RhoGEF [EC:2.7.11.1]
B TSSK family
C 101099943 TSSK6; testis-specific serine/threonine-protein kinase 6 K08811 TSSK; testis-specific serine kinase [EC:2.7.11.1]
C 101080294 TSSK4; testis-specific serine/threonine-protein kinase 4 isoform X1 K08811 TSSK; testis-specific serine kinase [EC:2.7.11.1]
C 101100236 TSSK3; testis-specific serine/threonine-protein kinase 3 isoform X1 K08811 TSSK; testis-specific serine kinase [EC:2.7.11.1]
C 101099155 TSSK2; testis-specific serine/threonine-protein kinase 2 K08811 TSSK; testis-specific serine kinase [EC:2.7.11.1]
C 101099406 testis-specific serine/threonine-protein kinase 1 K08811 TSSK; testis-specific serine kinase [EC:2.7.11.1]
B CDPK family
B CASK family
C 101090997 CASK; peripheral plasma membrane protein CASK isoform X14 K06103 CASK; calcium/calmodulin-dependent serine protein kinase [EC:2.7.11.1]
B Trbl family
C 101085367 TRIB2; tribbles homolog 2 isoform X1 K08814 TRIB1_2; tribbles homolog 1/2
C 101087043 TRIB1; tribbles homolog 1 K08814 TRIB1_2; tribbles homolog 1/2
C 101083255 TRIB3; tribbles homolog 3 K19518 TRIB3; tribbles homolog 3
B Other
C 101083704 STK33; serine/threonine-protein kinase 33 isoform X1 K08813 STK33; serine/threonine kinase 33 [EC:2.7.11.1]
C 101089124 STK40; serine/threonine-protein kinase 40 K16312 STK40; serine/threonine-protein kinase 40 [EC:2.7.11.1]
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ASerine/threonine kinases: CK1 group
B CK1 family [OT]
C 101085602 CSNK1A1; casein kinase I isoform X2 K08957 CSNK1A; casein kinase 1, alpha [EC:2.7.11.1]
C 101085017 CSNK1G3; casein kinase I isoform X5 K08958 CSNK1G; casein kinase 1, gamma [EC:2.7.11.1]
C 101100186 CSNK1G2; casein kinase I K08958 CSNK1G; casein kinase 1, gamma [EC:2.7.11.1]
C 101087842 CSNK1G1; casein kinase I isoform X1 K08958 CSNK1G; casein kinase 1, gamma [EC:2.7.11.1]
C 101091915 CSNK1D; casein kinase I isoform X2 K08959 CSNK1D; casein kinase 1, delta [EC:2.7.11.1]
C 101101321 casein kinase I isoform X1 K08960 CSNK1E; casein kinase 1, epsilon [EC:2.7.11.1]
B TTBK family
C 101081810 TTBK2; tau-tubulin kinase 2 isoform X1 K08815 TTBK; tau tubulin kinase [EC:2.7.11.26]
C 101093857 TTBK1; LOW QUALITY PROTEIN: tau-tubulin kinase 1 K08815 TTBK; tau tubulin kinase [EC:2.7.11.26]
B VRK family
C 101091879 VRK1; serine/threonine-protein kinase VRK1 isoform X1 K08816 VRK; vaccinia related kinase [EC:2.7.11.1]
C 101092656 VRK3; inactive serine/threonine-protein kinase VRK3 K08816 VRK; vaccinia related kinase [EC:2.7.11.1]
C 101098217 VRK2; serine/threonine-protein kinase VRK2 isoform X7 K08816 VRK; vaccinia related kinase [EC:2.7.11.1]
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ASerine/threonine kinases: CMGC group
B CDK family
C 101084656 CDK20; cyclin-dependent kinase 20 isoform X6 K08817 CCRK; cell cycle related kinase [EC:2.7.11.22]
C 101080954 cyclin-dependent kinase 11B isoform X1 K08818 CDC2L; cell division cycle 2-like [EC:2.7.11.22]
C 101101592 CDK1; cyclin-dependent kinase 1 K02087 CDK1; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
C 101093368 CDK2; cyclin-dependent kinase 2 isoform X2 K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
C 101082960 CDK3; cyclin-dependent kinase 3 isoform X1 K02088 CDK3; cyclin-dependent kinase 3 [EC:2.7.11.22]
C 101097903 CDK4; cyclin-dependent kinase 4 isoform X2 K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
C 101097226 CDK5; cyclin-dependent-like kinase 5 K02090 CDK5; cyclin-dependent kinase 5 [EC:2.7.11.22]
C 100037415 CDK6; cyclin-dependent kinase 6 K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
C 101086781 CDK7; cyclin-dependent kinase 7 isoform X3 K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
C 101086278 CDK8; cyclin-dependent kinase 8 isoform X1 K02208 CDK8_11; cyclin-dependent kinase 8/11 [EC:2.7.11.22 2.7.11.23]
C 101083850 CDK19; cyclin-dependent kinase 19 isoform X1 K02208 CDK8_11; cyclin-dependent kinase 8/11 [EC:2.7.11.22 2.7.11.23]
C 101097767 CDK9; cyclin-dependent kinase 9 K02211 CDK9; cyclin-dependent kinase 9 [EC:2.7.11.22 2.7.11.23]
C 101080500 CDK10; cyclin-dependent kinase 10 isoform X1 K02449 CDK10; cyclin-dependent kinase 10 [EC:2.7.11.22]
C 101090563 CDK12; cyclin-dependent kinase 12 isoform X3 K08819 CDK12_13; cyclin-dependent kinase 12/13 [EC:2.7.11.22 2.7.11.23]
C 101098044 CDK13; cyclin-dependent kinase 13 isoform X1 K08819 CDK12_13; cyclin-dependent kinase 12/13 [EC:2.7.11.22 2.7.11.23]
C 101081878 CDK14; cyclin-dependent kinase 14 isoform X2 K08821 CDK14; cyclin-dependent kinase 14 [EC:2.7.11.22]
C 101095120 CDK15; cyclin-dependent kinase 15 isoform X2 K15594 CDK15; cyclin-dependent kinase 15 [EC:2.7.11.22]
C 101094653 CDK16; cyclin-dependent kinase 16 isoform X2 K08820 CDK16; cyclin-dependent kinase 16 [EC:2.7.11.22]
C 101084463 CDK17; cyclin-dependent kinase 17 isoform X1 K15595 CDK17; cyclin-dependent kinase 17 [EC:2.7.11.22]
C 101085853 CDK18; cyclin-dependent kinase 18 isoform X1 K15596 CDK18; cyclin-dependent kinase 18 [EC:2.7.11.22]
B MAPK family [OT]
C 101087614 MAPK1; mitogen-activated protein kinase 1 K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
C 101087958 MAPK3; mitogen-activated protein kinase 3 isoform X2 K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
C 101093275 MAPK6; mitogen-activated protein kinase 6 K06855 MAPK4_6; mitogen-activated protein kinase 4/6 [EC:2.7.11.24]
C 101092057 MAPK4; mitogen-activated protein kinase 4 K06855 MAPK4_6; mitogen-activated protein kinase 4/6 [EC:2.7.11.24]
C 101097357 MAPK7; mitogen-activated protein kinase 7 K04464 MAPK7; mitogen-activated protein kinase 7 [EC:2.7.11.24]
C 101091508 MAPK15; mitogen-activated protein kinase 15 isoform X1 K19603 MAPK15; mitogen-activated protein kinase 15 [EC:2.7.11.24]
C 101091310 MAPK8; mitogen-activated protein kinase 8 isoform X1 K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
C 101101463 MAPK10; mitogen-activated protein kinase 10 isoform X3 K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
C 101084765 MAPK9; mitogen-activated protein kinase 9 isoform X1 K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
C 101101135 MAPK14; mitogen-activated protein kinase 14 isoform X1 K04441 P38; p38 MAP kinase [EC:2.7.11.24]
C 101091536 MAPK13; mitogen-activated protein kinase 13 isoform X1 K04441 P38; p38 MAP kinase [EC:2.7.11.24]
C 111556320 MAPK12; mitogen-activated protein kinase 12 K04441 P38; p38 MAP kinase [EC:2.7.11.24]
C 105260786 MAPK11; mitogen-activated protein kinase 11 isoform X1 K04441 P38; p38 MAP kinase [EC:2.7.11.24]
C 101080751 NLK; serine/threonine-protein kinase NLK K04468 NLK; nemo like kinase [EC:2.7.11.24]
B GSK family [OT]
C 101084151 GSK3A; glycogen synthase kinase-3 alpha K08822 GSK3A; glycogen synthase kinase 3 alpha [EC:2.7.11.26]
C 101081660 GSK3B; glycogen synthase kinase-3 beta isoform X2 K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
B CLK family
C 101087897 CLK4; dual specificity protein kinase CLK4 isoform X1 K23561 CLK1_4; dual specificity protein kinase CLK1/4 [EC:2.7.12.1]
C 101092384 CLK1; dual specificity protein kinase CLK1 isoform X1 K23561 CLK1_4; dual specificity protein kinase CLK1/4 [EC:2.7.12.1]
C 101088998 CLK2; dual specificity protein kinase CLK2 isoform X1 K08823 CLK2_3; dual specificity protein kinase CLK2/3 [EC:2.7.12.1]
C 101083851 CLK3; dual specificity protein kinase CLK3 K08823 CLK2_3; dual specificity protein kinase CLK2/3 [EC:2.7.12.1]
B CDKL family
C 101095572 CDKL4; cyclin-dependent kinase-like 4 K08824 CDKL; cyclin-dependent kinase-like [EC:2.7.11.22]
C 101094603 CDKL1; cyclin-dependent kinase-like 1 K08824 CDKL; cyclin-dependent kinase-like [EC:2.7.11.22]
C 101101561 CDKL2; cyclin-dependent kinase-like 2 K08824 CDKL; cyclin-dependent kinase-like [EC:2.7.11.22]
C 101099939 CDKL5; cyclin-dependent kinase-like 5 isoform X4 K08824 CDKL; cyclin-dependent kinase-like [EC:2.7.11.22]
C 101086198 CDKL3; cyclin-dependent kinase-like 3 isoform X2 K08824 CDKL; cyclin-dependent kinase-like [EC:2.7.11.22]
B DYRK family [OT]
C 101095062 DYRK1B; dual specificity tyrosine-phosphorylation-regulated kinase 1B isoform X5 K08825 DYRK1; dual specificity tyrosine-phosphorylation-regulated kinase 1 [EC:2.7.12.1]
C 101100581 DYRK1A; dual specificity tyrosine-phosphorylation-regulated kinase 1A isoform X1 K08825 DYRK1; dual specificity tyrosine-phosphorylation-regulated kinase 1 [EC:2.7.12.1]
C 101094686 DYRK2; dual specificity tyrosine-phosphorylation-regulated kinase 2 isoform X2 K18669 DYRK2_3_4; dual specificity tyrosine-phosphorylation-regulated kinase 2/3/4 [EC:2.7.12.1]
C 101091077 DYRK3; dual specificity tyrosine-phosphorylation-regulated kinase 3 isoform X1 K18669 DYRK2_3_4; dual specificity tyrosine-phosphorylation-regulated kinase 2/3/4 [EC:2.7.12.1]
C 101100313 DYRK4; dual specificity tyrosine-phosphorylation-regulated kinase 4 isoform X2 K18669 DYRK2_3_4; dual specificity tyrosine-phosphorylation-regulated kinase 2/3/4 [EC:2.7.12.1]
C 101093479 HIPK4; homeodomain-interacting protein kinase 4 K08826 HIPK; homeodomain interacting protein kinase [EC:2.7.11.1]
C 101091475 HIPK3; homeodomain-interacting protein kinase 3 isoform X7 K08826 HIPK; homeodomain interacting protein kinase [EC:2.7.11.1]
C 101101070 HIPK1; homeodomain-interacting protein kinase 1 isoform X1 K08826 HIPK; homeodomain interacting protein kinase [EC:2.7.11.1]
C 101081031 HIPK2; homeodomain-interacting protein kinase 2 isoform X1 K08826 HIPK; homeodomain interacting protein kinase [EC:2.7.11.1]
C 101082567 PRPF4B; serine/threonine-protein kinase PRP4 homolog isoform X1 K08827 PRPF4B; serine/threonine-protein kinase PRP4 [EC:2.7.11.1]
B RCK family [OT]
C 101085288 CILK1; serine/threonine-protein kinase ICK isoform X1 K08828 ICK; intestinal cell (MAK-like) kinase [EC:2.7.11.22]
C 101093856 MAK; serine/threonine-protein kinase MAK isoform X2 K08829 MAK; male germ cell-associated kinase [EC:2.7.11.22]
C 101082831 MOK; MAPK/MAK/MRK overlapping kinase isoform X1 K08830 RAGE; renal tumor antigen [EC:2.7.11.22]
B SRPK family [OT]
C 101100890 SRPK1; LOW QUALITY PROTEIN: SRSF protein kinase 1 K15409 SRPK1; serine/threonine-protein kinase SRPK1 [EC:2.7.11.1]
C 101084692 SRPK2; SRSF protein kinase 2 isoform X9 K08831 SRPK2; serine/threonine-protein kinase SRPK2 [EC:2.7.11.1]
C 105259684 SRPK3; SRSF protein kinase 3 isoform X1 K08832 SRPK3; serine/threonine-protein kinase SRPK3 [EC:2.7.11.1]
#
ASerine/threonine kinases: STE group
B STE7 family
C 101081387 MAP2K1; dual specificity mitogen-activated protein kinase kinase 1 isoform X3 K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
C 101100281 MAP2K2; dual specificity mitogen-activated protein kinase kinase 2 isoform X1 K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
C 101082274 MAP2K3; dual specificity mitogen-activated protein kinase kinase 3 K04432 MAP2K3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
C 101086432 MAP2K4; dual specificity mitogen-activated protein kinase kinase 4 isoform X1 K04430 MAP2K4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
C 101100725 MAP2K5; dual specificity mitogen-activated protein kinase kinase 5 isoform X1 K04463 MAP2K5; mitogen-activated protein kinase kinase 5 [EC:2.7.12.2]
C 101089813 MAP2K6; dual specificity mitogen-activated protein kinase kinase 6 isoform X1 K04433 MAP2K6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
C 101095157 MAP2K7; dual specificity mitogen-activated protein kinase kinase 7 isoform X1 K04431 MAP2K7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
B STE20 family
C 101101431 MAP4K1; mitogen-activated protein kinase kinase kinase kinase 1 isoform X1 K04408 MAP4K1; mitogen-activated protein kinase kinase kinase kinase 1 [EC:2.7.11.1]
C 101094701 MAP4K2; mitogen-activated protein kinase kinase kinase kinase 2 isoform X1 K04414 MAP4K2; mitogen-activated protein kinase kinase kinase kinase 2 [EC:2.7.11.1]
C 101098622 MAP4K3; mitogen-activated protein kinase kinase kinase kinase 3 isoform X1 K04406 MAP4K3; mitogen-activated protein kinase kinase kinase kinase 3 [EC:2.7.11.1]
C 101081214 MAP4K4; mitogen-activated protein kinase kinase kinase kinase 4 isoform X29 K04407 MAP4K4; mitogen-activated protein kinase kinase kinase kinase 4 [EC:2.7.11.1]
C 101095501 MAP4K5; mitogen-activated protein kinase kinase kinase kinase 5 isoform X1 K08833 MAP4K5; mitogen-activated protein kinase kinase kinase kinase 5 [EC:2.7.11.1]
C 101092806 MINK1; misshapen-like kinase 1 isoform X5 K04413 MINK; misshapen/NIK-related kinase [EC:2.7.11.1]
C 101084310 TNIK; LOW QUALITY PROTEIN: TRAF2 and NCK-interacting protein kinase K08840 TNIK; TRAF2 and NCK interacting kinase [EC:2.7.11.1]
C 101100286 NRK; nik-related protein kinase isoform X1 K16313 NRK; Nik-related protein kinase [EC:2.7.11.1]
C 101088260 MYO3B; myosin-IIIb isoform X1 K08834 MYO3; myosin III [EC:2.7.11.1]
C 101086983 MYO3A; myosin-IIIa isoform X2 K08834 MYO3; myosin III [EC:2.7.11.1]
C 101080733 OXSR1; serine/threonine-protein kinase OSR1 isoform X1 K08835 OXSR1; serine/threonine-protein kinase OSR1/STK39 [EC:2.7.11.1]
C 101087086 STK39; STE20/SPS1-related proline-alanine-rich protein kinase isoform X3 K08835 OXSR1; serine/threonine-protein kinase OSR1/STK39 [EC:2.7.11.1]
C 101087171 PAK1; serine/threonine-protein kinase PAK 1 K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
C 101082845 PAK2; serine/threonine-protein kinase PAK 2 K04410 PAK2; p21-activated kinase 2 [EC:2.7.11.1]
C 101092248 PAK3; serine/threonine-protein kinase PAK 3 isoform X1 K05733 PAK3; p21-activated kinase 3 [EC:2.7.11.1]
C 101098348 PAK4; serine/threonine-protein kinase PAK 4 isoform X1 K05734 PAK4; p21-activated kinase 4 [EC:2.7.11.1]
C 101091011 PAK5; serine/threonine-protein kinase PAK 5 K05736 PAK5; p21-activated kinase 5 [EC:2.7.11.1]
C 101091201 PAK6; serine/threonine-protein kinase PAK 6 K05735 PAK6; p21-activated kinase 6 [EC:2.7.11.1]
C 101096609 SLK; STE20-like serine/threonine-protein kinase isoform X2 K08836 SLK; STE20-like kinase [EC:2.7.11.1]
C 101098281 STK10; serine/threonine-protein kinase 10 isoform X1 K08837 STK10; serine/threonine kinase 10 [EC:2.7.11.1]
C 101095531 STRADA; STE20-related kinase adapter protein alpha isoform X1 K08271 STRADA; STE20-related kinase adapter protein alpha
C 101094615 STRADB; STE20-related kinase adapter protein beta isoform X1 K17532 STRADB; STE20-related kinase adapter protein beta
C 101081440 STK3; serine/threonine-protein kinase 3 isoform X1 K04412 STK3; serine/threonine kinase 3
C 101091185 STK4; serine/threonine-protein kinase 4 isoform X1 K04411 STK4; serine/threonine kinase 4
C 101098426 STK24; serine/threonine-protein kinase 24 isoform X1 K08838 STK24_25_MST4; serine/threonine-protein kinase 24/25/MST4 [EC:2.7.11.1]
C 101091135 STK25; LOW QUALITY PROTEIN: serine/threonine-protein kinase 25 K08838 STK24_25_MST4; serine/threonine-protein kinase 24/25/MST4 [EC:2.7.11.1]
C 101084861 STK26; serine/threonine-protein kinase 26 K08838 STK24_25_MST4; serine/threonine-protein kinase 24/25/MST4 [EC:2.7.11.1]
C 101092716 TAOK1; serine/threonine-protein kinase TAO1 isoform X2 K04429 TAO; thousand and one amino acid protein kinase [EC:2.7.11.1]
C 101093052 TAOK3; serine/threonine-protein kinase TAO3 isoform X1 K04429 TAO; thousand and one amino acid protein kinase [EC:2.7.11.1]
C 101099348 TAOK2; serine/threonine-protein kinase TAO2 isoform X2 K04429 TAO; thousand and one amino acid protein kinase [EC:2.7.11.1]
B STE11 family
C 101090328 MAP3K1; mitogen-activated protein kinase kinase kinase 1 isoform X1 K04416 MAP3K1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]
C 101096406 MAP3K2; mitogen-activated protein kinase kinase kinase 2 isoform X1 K04420 MAP3K2; mitogen-activated protein kinase kinase kinase 2 [EC:2.7.11.25]
C 101083633 MAP3K3; mitogen-activated protein kinase kinase kinase 3 isoform X2 K04421 MAP3K3; mitogen-activated protein kinase kinase kinase 3 [EC:2.7.11.25]
C 101097977 MAP3K4; mitogen-activated protein kinase kinase kinase 4 isoform X1 K04428 MAP3K4; mitogen-activated protein kinase kinase kinase 4 [EC:2.7.11.25]
C 101082912 MAP3K5; mitogen-activated protein kinase kinase kinase 5 isoform X1 K04426 MAP3K5; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
C 101081315 MAP3K6; mitogen-activated protein kinase kinase kinase 6 isoform X1 K04425 MAP3K6; mitogen-activated protein kinase kinase kinase 6 [EC:2.7.11.25]
C 101089836 MAP3K15; mitogen-activated protein kinase kinase kinase 15 isoform X1 K13986 MAP3K15; mitogen-activated protein kinase kinase kinase 15 [EC:2.7.11.25]
C 101090454 MAP3K19; mitogen-activated protein kinase kinase kinase 19 isoform X2 K17533 MAP3K19; mitogen-activated protein kinase kinase kinase 19 [EC:2.7.11.25]
B Other
C 101090624 MAP3K8; mitogen-activated protein kinase kinase kinase 8 K04415 MAP3K8; mitogen-activated protein kinase kinase kinase 8 [EC:2.7.11.25]
C 101083468 MAP3K14; mitogen-activated protein kinase kinase kinase 14 K04466 MAP3K14; mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]
#
ASerine/threonine kinases: TKL group
B IRAK family
C 101090500 IRAK1; interleukin-1 receptor-associated kinase 1 isoform X1 K04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
C 101086888 IRAK2; interleukin-1 receptor-associated kinase-like 2 isoform X3 K04731 IRAK2; interleukin-1 receptor-associated kinase 2 [EC:2.7.11.1]
C 101093197 IRAK3; interleukin-1 receptor-associated kinase 3 isoform X1 K04732 IRAK3; interleukin-1 receptor-associated kinase 3 [EC:2.7.11.1]
C 101100225 IRAK4; interleukin-1 receptor-associated kinase 4 isoform X1 K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
B LISK family [OT]
C 101097861 LIMK1; LIM domain kinase 1 isoform X1 K05743 LIMK1; LIM domain kinase 1 [EC:2.7.11.1]
C 101096766 LIMK2; LIM domain kinase 2 isoform X2 K05744 LIMK2; LIM domain kinase 2 [EC:2.7.11.1]
C 101086512 TESK1; dual specificity testis-specific protein kinase 1 K08841 TESK1; testis-specific kinase 1 [EC:2.7.12.1]
C 101090279 TESK2; dual specificity testis-specific protein kinase 2 isoform X1 K08842 TESK2; testis-specific kinase 2 [EC:2.7.12.1]
B LRRK family
C 101082914 LRRK1; leucine-rich repeat serine/threonine-protein kinase 1 isoform X2 K08843 LRRK1; leucine-rich repeat kinase 1 [EC:2.7.11.1]
C 101096157 LRRK2; leucine-rich repeat serine/threonine-protein kinase 2 isoform X1 K08844 LRRK2; leucine-rich repeat kinase 2 [EC:2.7.11.1]
B MLK family
C 101095899 MAP3K7; mitogen-activated protein kinase kinase kinase 7 isoform X1 K04427 MAP3K7; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
C 101084717 MAP3K9; mitogen-activated protein kinase kinase kinase 9 isoform X2 K04417 MAP3K9; mitogen-activated protein kinase kinase kinase 9 [EC:2.7.11.25]
C 101089731 MAP3K10; LOW QUALITY PROTEIN: mitogen-activated protein kinase kinase kinase 10 K04418 MAP3K10; mitogen-activated protein kinase kinase kinase 10 [EC:2.7.11.25]
C 101098654 MAP3K11; mitogen-activated protein kinase kinase kinase 11 K04419 MAP3K11; mitogen-activated protein kinase kinase kinase 11 [EC:2.7.11.25]
C 101087784 MAP3K21; mitogen-activated protein kinase kinase kinase 21 isoform X1 K17534 MLK4; mitogen-activated protein kinase kinase kinase MLK4 [EC:2.7.11.25]
C 101094038 MAP3K20; mitogen-activated protein kinase kinase kinase 20 K04424 ZAK; sterile alpha motif and leucine zipper containing kinase AZK [EC:2.7.11.25]
C 101087164 MAP3K12; mitogen-activated protein kinase kinase kinase 12 K04423 MAP3K12; mitogen-activated protein kinase kinase kinase 12 [EC:2.7.11.25]
C 101093205 MAP3K13; mitogen-activated protein kinase kinase kinase 13 isoform X3 K04422 MAP3K13; mitogen-activated protein kinase kinase kinase 13 [EC:2.7.11.25]
C 101085560 serine/threonine-protein kinase TNNI3K isoform X4 K17535 TNNI3K; serine/threonine-protein kinase TNNI3K [EC:2.7.11.1]
C 101092790 ILK; integrin-linked protein kinase isoform X1 K06272 ILK; integrin-linked kinase [EC:2.7.11.1]
B RAF family [OT]
C 101089839 ARAF; serine/threonine-protein kinase A-Raf isoform X2 K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
C 101092346 BRAF; serine/threonine-protein kinase B-raf isoform X5 K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
C 101096047 RAF1; RAF proto-oncogene serine/threonine-protein kinase isoform X2 K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
C 101092156 KSR1; kinase suppressor of Ras 1 isoform X11 K14958 KSR1; kinase suppressor of Ras 1
C 101091904 KSR2; kinase suppressor of Ras 2 isoform X1 K18529 KSR2; kinase suppressor of Ras 2 [EC:2.7.11.1]
B RIPK family [OT]
C 101087663 RIPK1; receptor-interacting serine/threonine-protein kinase 1 isoform X1 K02861 RIPK1; receptor-interacting serine/threonine-protein kinase 1 [EC:2.7.11.1]
C 101086783 RIPK2; receptor-interacting serine/threonine-protein kinase 2 isoform X1 K08846 RIPK2; receptor-interacting serine/threonine-protein kinase 2 [EC:2.7.11.1]
C 101097985 RIPK3; receptor-interacting serine/threonine-protein kinase 3 isoform X1 K08847 RIPK3; receptor-interacting serine/threonine-protein kinase 3 [EC:2.7.11.1]
C 101095278 RIPK4; receptor-interacting serine/threonine-protein kinase 4 isoform X1 K08848 RIPK4; receptor-interacting serine/threonine-protein kinase 4 [EC:2.7.11.1]
C 101081829 ANKK1; ankyrin repeat and protein kinase domain-containing protein 1 K16289 ANKK1; ankyrin repeat and protein kinase domain-containing protein 1 [EC:2.7.11.1]
B Other
#
ASerine/threonine kinases: Other
B RGC family [OT]
C 101080682 NPR1; atrial natriuretic peptide receptor 1 isoform X3 K12323 ANPRA; atrial natriuretic peptide receptor A [EC:4.6.1.2]
C 101094301 NPR2; atrial natriuretic peptide receptor 2 isoform X2 K12324 ANPRB; atrial natriuretic peptide receptor B [EC:4.6.1.2]
C 101095109 GUCY2C; heat-stable enterotoxin receptor isoform X3 K12320 GUCY2C; heat-stable enterotoxin receptor [EC:4.6.1.2]
C 101101009 GUCY2D; retinal guanylyl cyclase 1 K12321 GUCY2D_E; guanylate cyclase 2D/E [EC:4.6.1.2]
C 101099582 guanylate cyclase D-like K12321 GUCY2D_E; guanylate cyclase 2D/E [EC:4.6.1.2]
C 101090242 GUCY2F; retinal guanylyl cyclase 2 K12322 GUCY2F; guanylate cyclase 2F [EC:4.6.1.2]
B BUB family
C 101085035 BUB1; mitotic checkpoint serine/threonine-protein kinase BUB1 K02178 BUB1; checkpoint serine/threonine-protein kinase [EC:2.7.11.1]
C 101087670 BUB1B; mitotic checkpoint serine/threonine-protein kinase BUB1 beta isoform X1 K06637 BUB1B; mitotic checkpoint serine/threonine-protein kinase BUB1 beta [EC:2.7.11.1]
B Bud32 family
C 101084351 TP53RK; EKC/KEOPS complex subunit TP53RK K08851 TP53RK; TP53 regulating kinase and related kinases [EC:2.7.11.1]
B CAMKK family
C 101091320 CAMKK1; calcium/calmodulin-dependent protein kinase kinase 1 isoform X1 K00908 CAMKK1; calcium/calmodulin-dependent protein kinase kinase 1 [EC:2.7.11.17]
C 101097674 CAMKK2; calcium/calmodulin-dependent protein kinase kinase 2 isoform X1 K07359 CAMKK2; calcium/calmodulin-dependent protein kinase kinase 2 [EC:2.7.11.17]
B CDC7 family
C 101085227 CDC7; cell division cycle 7-related protein kinase isoform X1 K02214 CDC7; cell division control protein 7 [EC:2.7.11.1]
B CK2 family
C 101084186 CSNK2A1; casein kinase II subunit alpha K03097 CSNK2A; casein kinase II subunit alpha [EC:2.7.11.1]
C 101093065 CSNK2A2; casein kinase II subunit alpha' isoform X1 K03097 CSNK2A; casein kinase II subunit alpha [EC:2.7.11.1]
B Haspin family
C 101091825 HASPIN; LOW QUALITY PROTEIN: serine/threonine-protein kinase haspin K16315 GSG2; serine/threonine-protein kinase haspin [EC:2.7.11.1]
B IKK family [OT]
C 101095617 CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1 K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
C 100142682 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta isoform X2 K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
C 101086544 IKBKG; NF-kappa-B essential modulator isoform X1 K07210 IKBKG; inhibitor of nuclear factor kappa-B kinase subunit gamma
C 101086282 IKBKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon isoform X1 K07211 IKBKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10]
C 101091955 TBK1; serine/threonine-protein kinase TBK1 isoform X1 K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
B IRE family
C 101084148 ERN1; serine/threonine-protein kinase/endoribonuclease IRE1 isoform X1 K08852 ERN1; serine/threonine-protein kinase/endoribonuclease IRE1 [EC:2.7.11.1 3.1.26.-]
C 101089482 ERN2; serine/threonine-protein kinase/endoribonuclease IRE2 isoform X3 K11715 ERN2; serine/threonine-protein kinase/endoribonuclease IRE2 [EC:2.7.11.1 3.1.26.-]
B MOS family
C 101081699 MOS; proto-oncogene serine/threonine-protein kinase mos K04367 MOS; proto-oncogene serine/threonine-protein kinase mos [EC:2.7.11.1]
B NAK family [OT]
C 101094013 AAK1; AP2-associated protein kinase 1 isoform X4 K08853 AAK; AP2-associated kinase [EC:2.7.11.1]
C 101094669 BMP2K; BMP-2-inducible protein kinase isoform X1 K08854 BMP2K; BMP2 inducible kinase [EC:2.7.11.1]
C 101094018 GAK; cyclin-G-associated kinase isoform X4 K08855 GAK; cyclin G-associated kinase [EC:2.7.11.1]
C 101095674 STK16; serine/threonine-protein kinase 16 isoform X1 K08856 STK16; serine/threonine kinase 16 [EC:2.7.11.1]
B NEK family
C 101093171 NEK4; serine/threonine-protein kinase Nek4 isoform X2 K08857 NEK1_4_5; serine/threonine-protein kinase Nek1/4/5 [EC:2.7.11.1]
C 101094016 NEK1; serine/threonine-protein kinase Nek1 isoform X4 K08857 NEK1_4_5; serine/threonine-protein kinase Nek1/4/5 [EC:2.7.11.1]
C 101097612 NEK5; serine/threonine-protein kinase Nek5 isoform X1 K08857 NEK1_4_5; serine/threonine-protein kinase Nek1/4/5 [EC:2.7.11.1]
C 101085774 NEK2; serine/threonine-protein kinase Nek2 K20872 NEK2; serine/threonine-protein kinase Nek2 [EC:2.7.11.1]
C 102900290 NEK3; serine/threonine-protein kinase Nek3 isoform X1 K20873 NEK3; serine/threonine-protein kinase Nek3 [EC:2.7.11.1]
C 101080747 NEK6; serine/threonine-protein kinase Nek6 isoform X1 K20875 NEK6; serine/threonine-protein kinase Nek6 [EC:2.7.11.34]
C 101093327 NEK7; serine/threonine-protein kinase Nek7 isoform X1 K20876 NEK7; serine/threonine-protein kinase Nek7 [EC:2.7.11.34]
C 101084837 NEK8; serine/threonine-protein kinase Nek8 isoform X7 K20877 NEK8; serine/threonine-protein kinase Nek8 [EC:2.7.11.1]
C 101083774 NEK9; serine/threonine-protein kinase Nek9 K20878 NEK9; serine/threonine-protein kinase Nek9 [EC:2.7.11.1]
C 101087091 NEK10; serine/threonine-protein kinase Nek10 isoform X1 K20879 NEK10; serine/threonine-protein kinase Nek10 [EC:2.7.11.1]
C 101095192 NEK11; serine/threonine-protein kinase Nek11 isoform X5 K20880 NEK11; serine/threonine-protein kinase Nek11 [EC:2.7.11.1]
B NKF1 family
C 101094813 SBK1; serine/threonine-protein kinase SBK1 K08858 SBK; serine/threonine-protein kinase SBK [EC:2.7.11.1]
C 101089559 SBK2; serine/threonine-protein kinase SBK2 K08858 SBK; serine/threonine-protein kinase SBK [EC:2.7.11.1]
C 101089309 SBK3; uncharacterized serine/threonine-protein kinase SBK3 K08858 SBK; serine/threonine-protein kinase SBK [EC:2.7.11.1]
B NKF2 family
C 101093033 PINK1; serine/threonine-protein kinase PINK1, mitochondrial isoform X1 K05688 PINK1; PTEN induced putative kinase 1 [EC:2.7.11.1]
B NKF3 family
C 101087831 PRAG1; inactive tyrosine-protein kinase PRAG1 isoform X1 K17537 SGK223; tyrosine-protein kinase SgK223 [EC:2.7.10.2]
C 101096069 PEAK1; inactive tyrosine-protein kinase PEAK1 K17538 PEAK1; pseudopodium-enriched atypical kinase 1 [EC:2.7.10.2]
B NKF4 family
C 101084276 STK35; serine/threonine-protein kinase 35 isoform X1 K08859 STK35; serine/threonine kinase 35 [EC:2.7.11.1]
C 101084212 PDIK1L; serine/threonine-protein kinase PDIK1L K17539 PDIK1L; serine/threonine-protein kinase PDIK1L [EC:2.7.11.1]
B NKF5 family
C 101096273 TEX14; inactive serine/threonine-protein kinase TEX14 isoform X5 K17540 TEX14; inactive serine/threonine-protein kinase TEX14
B NRBP family
C 101096975 NRBP1; nuclear receptor-binding protein isoform X2 K08875 NRBP; nuclear receptor-binding protein
C 101099689 NRBP2; nuclear receptor-binding protein 2 isoform X3 K08875 NRBP; nuclear receptor-binding protein
B PEK family [OT]
C 101081103 EIF2AK1; eukaryotic translation initiation factor 2-alpha kinase 1 isoform X1 K16194 EIF2AK1; eukaryotic translation initiation factor 2-alpha kinase 1 [EC:2.7.11.1]
C 101082744 EIF2AK2; interferon-induced, double-stranded RNA-activated protein kinase isoform X3 K16195 EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]
C 101095973 EIF2AK3; eukaryotic translation initiation factor 2-alpha kinase 3 isoform X1 K08860 EIF2AK3; eukaryotic translation initiation factor 2-alpha kinase 3 [EC:2.7.11.1]
C 101087928 EIF2AK4; eIF-2-alpha kinase GCN2 isoform X1 K16196 EIF2AK4; eukaryotic translation initiation factor 2-alpha kinase 4 [EC:2.7.11.1]
B PLK family [OT]
C 101098508 PLK1; serine/threonine-protein kinase PLK1 K06631 PLK1; polo-like kinase 1 [EC:2.7.11.21]
C 101092083 PLK2; serine/threonine-protein kinase PLK2 K08861 PLK2; polo-like kinase 2 [EC:2.7.11.21]
C 101088599 PLK3; serine/threonine-protein kinase PLK3 K08862 PLK3; polo-like kinase 3 [EC:2.7.11.21]
C 101086791 PLK4; serine/threonine-protein kinase PLK4 K08863 PLK4; polo-like kinase 4 [EC:2.7.11.21]
B SCY1 family [OT]
C 101085831 SCYL1; LOW QUALITY PROTEIN: N-terminal kinase-like protein K08876 SCYL1; SCY1-like protein 1
C 101080722 SCYL2; SCY1-like protein 2 isoform X2 K17541 SCYL2; SCY1-like protein 2
C 101084081 SCYL3; protein-associating with the carboxyl-terminal domain of ezrin isoform X4 K17542 SCYL3; SCY1-like protein 3
B Slob family
C 101100115 PXK; PX domain-containing protein kinase-like protein isoform X11 K17543 PXK; PX domain-containing protein kinase-like protein
B TBCK family
C 101090610 TBCK; TBC domain-containing protein kinase-like protein isoform X1 K17544 TBCK; TBC domain-containing protein kinase-like protein
B TLK family
C 101088770 TLK1; serine/threonine-protein kinase tousled-like 1 K08864 TLK; tousled-like kinase [EC:2.7.11.1]
C 101093158 TLK2; serine/threonine-protein kinase tousled-like 2 isoform X6 K08864 TLK; tousled-like kinase [EC:2.7.11.1]
B TOPK family
C 101080784 PBK; lymphokine-activated killer T-cell-originated protein kinase isoform X2 K08865 PBK; PDZ-binding kinase [EC:2.7.12.2]
C 123383412 lymphokine-activated killer T-cell-originated protein kinase-like K08865 PBK; PDZ-binding kinase [EC:2.7.12.2]
B TTK family
C 101101566 TTK; dual specificity protein kinase TTK isoform X1 K08866 TTK; serine/threonine-protein kinase TTK/MPS1 [EC:2.7.12.1]
B ULK family [OT]
C 101091390 STK36; serine/threonine-protein kinase 36 isoform X2 K06228 FU; fused [EC:2.7.11.1]
C 101098658 ULK1; serine/threonine-protein kinase ULK1 isoform X1 K21357 ULK1; serine/threonine-protein kinase ULK1 [EC:2.7.11.1]
C 101083981 ULK2; serine/threonine-protein kinase ULK2 isoform X1 K08269 ULK2; serine/threonine-protein kinase ULK2 [EC:2.7.11.1]
C 101082826 ULK3; serine/threonine-protein kinase ULK3 isoform X1 K21358 ULK3; serine/threonine-protein kinase ULK3 [EC:2.7.11.1]
C 101082773 ULK4; serine/threonine-protein kinase ULK4 isoform X1 K17545 ULK4; serine/threonine-protein kinase ULK4 [EC:2.7.11.1]
B VPS15 family
C 101091893 PIK3R4; phosphoinositide 3-kinase regulatory subunit 4 isoform X1 K08333 PIK3R4; phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1]
B WEE family
C 101098425 PKMYT1; membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase isoform X1 K06633 PKMYT; membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase [EC:2.7.11.1]
C 101091897 WEE1; wee1-like protein kinase isoform X2 K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]
C 101093092 WEE2; wee1-like protein kinase 2 isoform X1 K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]
B Wnk family
C 101093000 WNK3; serine/threonine-protein kinase WNK3 isoform X2 K08867 WNK; WNK lysine deficient protein kinase [EC:2.7.11.1]
C 101100264 WNK4; serine/threonine-protein kinase WNK4 isoform X5 K08867 WNK; WNK lysine deficient protein kinase [EC:2.7.11.1]
C 101092650 WNK2; LOW QUALITY PROTEIN: serine/threonine-protein kinase WNK2 K08867 WNK; WNK lysine deficient protein kinase [EC:2.7.11.1]
C 101096818 WNK1; LOW QUALITY PROTEIN: serine/threonine-protein kinase WNK1 K08867 WNK; WNK lysine deficient protein kinase [EC:2.7.11.1]
B ABC1 family
C 101082139 ADCK2; uncharacterized aarF domain-containing protein kinase 2 isoform X1 K08869 ADCK; aarF domain-containing kinase
C 101086817 ADCK1; aarF domain-containing protein kinase 1 isoform X2 K08869 ADCK; aarF domain-containing kinase
C 101091064 COQ8B; atypical kinase COQ8B, mitochondrial isoform X1 K08869 ADCK; aarF domain-containing kinase
C 101096446 ADCK5; uncharacterized aarF domain-containing protein kinase 5 isoform X1 K08869 ADCK; aarF domain-containing kinase
C 101087805 COQ8A; atypical kinase COQ8A, mitochondrial K08869 ADCK; aarF domain-containing kinase
B Alpha family [OT]
C 101084874 ALPK1; alpha-protein kinase 1 isoform X1 K08868 ALPK; alpha-kinase
C 101086567 ALPK3; alpha-protein kinase 3 isoform X1 K08868 ALPK; alpha-kinase
C 101088624 ALPK2; alpha-protein kinase 2 isoform X2 K08868 ALPK; alpha-kinase
C 101092301 TRPM6; transient receptor potential cation channel subfamily M member 6 isoform X2 K04981 TRPM6; transient receptor potential cation channel subfamily M member 6 [EC:2.7.11.1]
C 101095177 TRPM7; transient receptor potential cation channel subfamily M member 7 isoform X1 K04982 TRPM7; transient receptor potential cation channel subfamily M member 7 [EC:2.7.11.1]
C 101101433 EEF2K; eukaryotic elongation factor 2 kinase K08292 EEF2K; elongation factor 2 kinase [EC:2.7.11.20]
B BCR family
C 101101671 BCR; breakpoint cluster region protein isoform X1 K08878 BCR1; breakpoint cluster region protein [EC:2.7.11.1]
B BRD family [OT]
C 111556174 BRD2; bromodomain-containing protein 2 isoform X1 K08871 BRD2; bromodomain-containing protein 2
C 101086013 BRD3; bromodomain-containing protein 3 isoform X1 K11721 BRD3; bromodomain-containing protein 3
C 101100035 BRD4; bromodomain-containing protein 4 isoform X1 K11722 BRD4; bromodomain-containing protein 4
C 101096661 BRDT; bromodomain testis-specific protein K11724 BRDT; bromodomain testis-specific protein
B FAST family
C 101082140 FASTK; fas-activated serine/threonine kinase isoform X2 K08290 FASTK; Fas-activated serine/threonine kinase [EC:2.7.11.8]
B G11 family
C 101101310 STK19; serine/threonine-protein kinase 19 isoform X2 K08880 STK19; serine/threonine kinase 19 [EC:2.7.11.1]
B H11 family
C 101093804 HSPB8; heat shock protein beta-8 K08879 HSPB8; heat shock protein beta-8
B PDHK family [OT]
C 101092705 PDK1; pyruvate dehydrogenase (acetyl-transferring) kinase isozyme 1, mitochondrial isoform X1 K12077 PDK1; pyruvate dehydrogenase kinase isoform 1 [EC:2.7.11.2]
C 101092256 PDK4; pyruvate dehydrogenase kinase, isozyme 4 K00898 PDK2_3_4; pyruvate dehydrogenase kinase 2/3/4 [EC:2.7.11.2]
C 101100013 PDK2; pyruvate dehydrogenase kinase, isozyme 2 isoform X1 K00898 PDK2_3_4; pyruvate dehydrogenase kinase 2/3/4 [EC:2.7.11.2]
C 101095314 PDK3; pyruvate dehydrogenase kinase, isozyme 3 isoform X3 K00898 PDK2_3_4; pyruvate dehydrogenase kinase 2/3/4 [EC:2.7.11.2]
C 101089414 BCKDK; 3-methyl-2-oxobutanoate dehydrogenase [lipoamide] kinase, mitochondrial isoform X1 K00905 BCKDK; [3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase [EC:2.7.11.4]
B PIKK family [OT]
C 101089291 ATM; serine-protein kinase ATM isoform X1 K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
C 101088023 ATR; serine/threonine-protein kinase ATR isoform X1 K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
C 101098152 MTOR; serine/threonine-protein kinase mTOR isoform X3 K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
C 101088389 PRKDC; DNA-dependent protein kinase catalytic subunit isoform X1 K06642 PRKDC; DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1]
C 101096436 SMG1; serine/threonine-protein kinase SMG1 isoform X1 K08873 SMG1; serine/threonine-protein kinase SMG1 [EC:2.7.11.1]
C 101083988 TRRAP; transformation/transcription domain-associated protein isoform X1 K08874 TRRAP; transformation/transcription domain-associated protein
B RIO family [OT]
C 101094944 RIOK1; serine/threonine-protein kinase RIO1 isoform X2 K07178 RIOK1; RIO kinase 1 [EC:2.7.11.1]
C 101083569 RIOK2; serine/threonine-protein kinase RIO2 isoform X1 K07179 RIOK2; RIO kinase 2 [EC:2.7.11.1]
C 101099174 serine/threonine-protein kinase RIO2-like K07179 RIOK2; RIO kinase 2 [EC:2.7.11.1]
C 101096925 RIOK3; serine/threonine-protein kinase RIO3 isoform X2 K08872 RIOK3; RIO kinase 3 [EC:2.7.11.1]
B TAF1 family
C 101093583 TAF1; transcription initiation factor TFIID subunit 1 isoform X8 K03125 TAF1; transcription initiation factor TFIID subunit 1 [EC:2.3.1.48 2.7.11.1]
C 101087372 CIITA; MHC class II transactivator isoform X1 K08060 CIITA; MHC class II transactivator [EC:2.7.11.1]
B TIF1 family [OT]
C 101089090 TRIM24; transcription intermediary factor 1-alpha isoform X1 K08881 TRIM24; tripartite motif-containing protein 24 [EC:2.3.2.27]
C 101086190 TRIM28; transcription intermediary factor 1-beta K08882 TRIM28; tripartite motif-containing protein 28 [EC:2.3.2.27]
C 101099107 TRIM33; E3 ubiquitin-protein ligase TRIM33 isoform X1 K08883 TRIM33; tripartite motif-containing protein 33 [EC:2.3.2.27]
B Other
C 101085524 UHMK1; serine/threonine-protein kinase Kist isoform X1 K08877 UHMK1; serine/threonine-protein kinase Kist [EC:2.7.11.1]
C 101097051 DCAF1; DDB1- and CUL4-associated factor 1 isoform X2 K11789 DCAF1; DDB1- and CUL4-associated factor 1 [EC:2.7.11.1]
C 101092014 STK31; serine/threonine-protein kinase 31 isoform X1 K16316 STK31; serine/threonine-protein kinase 31 [EC:2.7.11.1]
C 102902090 POMK; protein O-mannose kinase isoform X2 K17547 SGK196; glycoprotein-mannosyl O6-kinase [EC:2.7.1.183]
C 101085430 DSTYK; dual serine/threonine and tyrosine protein kinase isoform X1 K16288 DSTYK; dual serine/threonine and tyrosine protein kinase [EC:2.7.12.1]
C 101087277 STKLD1; serine/threonine kinase-like domain-containing protein STKLD1 isoform X2 K17546 STKLD1; serine/threonine kinase-like domain-containing protein STKLD1
B Bacterial family
#
AReceptor serine/threonine kinases (RSTK): TKL group
B TGFBR1 family [OT]
C 101091298 ACVR1; activin receptor type-1 K04675 ACVR1; activin receptor type-1 [EC:2.7.11.30]
C 101097406 ACVRL1; serine/threonine-protein kinase receptor R3 isoform X1 K13594 ACVRL1; activin receptor-like kinase 1 [EC:2.7.11.30]
C 101097654 ACVR1B; activin receptor type-1B isoform X1 K13567 ACVR1B; activin receptor type-1B [EC:2.7.11.30]
C 101091037 ACVR1C; activin receptor type-1C K13568 ACVR1C; activin receptor type-1C [EC:2.7.11.30]
C 101089548 BMPR1A; bone morphogenetic protein receptor type-1A K04673 BMPR1A; bone morphogenetic protein receptor type-1A [EC:2.7.11.30]
C 101082489 BMPR1B; bone morphogenetic protein receptor type-1B isoform X3 K13578 BMPR1B; bone morphogenetic protein receptor type-1B [EC:2.7.11.30]
C 101094057 TGFBR1; TGF-beta receptor type-1 isoform X1 K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
B TGFBR2 family [OT]
C 101097750 ACVR2A; activin receptor type-2A isoform X2 K04670 ACVR2A; activin receptor type-2A [EC:2.7.11.30]
C 101086087 ACVR2B; activin receptor type-2B isoform X1 K13596 ACVR2B; activin receptor type-2B [EC:2.7.11.30]
C 101085902 AMHR2; anti-Muellerian hormone type-2 receptor isoform X1 K04672 AMHR2; anti-mullerian hormone receptor type-2 [EC:2.7.11.30]
C 101096338 BMPR2; bone morphogenetic protein receptor type-2 K04671 BMPR2; bone morphogenetic protein receptor type-2 [EC:2.7.11.30]
C 101091725 TGFBR2; TGF-beta receptor type-2 isoform X2 K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
#
AReceptor tyrosine kinases (RTK)
B EGFR family [OT]
C 100510799 EGFR; epidermal growth factor receptor isoform X1 K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
C 751824 ERBB2; receptor tyrosine-protein kinase erbB-2 precursor K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
C 101085388 ERBB3; receptor tyrosine-protein kinase erbB-3 precursor K05084 ERBB3; receptor tyrosine-protein kinase erbB-3 [EC:2.7.10.1]
C 101100073 ERBB4; receptor tyrosine-protein kinase erbB-4 isoform X2 K05085 ERBB4; receptor tyrosine-protein kinase erbB-4 [EC:2.7.10.1]
B INSR family [OT]
C 101081861 INSRR; insulin receptor-related protein isoform X1 K05086 INSRR; insulin receptor-related receptor [EC:2.7.10.1]
C 100127108 INSR; insulin receptor isoform X1 K04527 INSR; insulin receptor [EC:2.7.10.1]
C 100500937 IGF1R; insulin-like growth factor 1 receptor isoform X1 K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
B PDGFR family [OT]
C 101090765 PDGFRA; platelet-derived growth factor receptor alpha K04363 PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
C 101084600 PDGFRB; platelet-derived growth factor receptor beta isoform X1 K05089 PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
C 493706 CSF1R; macrophage colony-stimulating factor 1 receptor precursor K05090 CSF1R; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
C 493766 KIT; mast/stem cell growth factor receptor Kit precursor K05091 KIT; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
C 101099264 FLT3; receptor-type tyrosine-protein kinase FLT3 K05092 FLT3; fms-related tyrosine kinase 3 [EC:2.7.10.1]
B FGFR family [OT]
C 101086055 FGFR1; fibroblast growth factor receptor 1 isoform X1 K04362 FGFR1; fibroblast growth factor receptor 1 [EC:2.7.10.1]
C 101095198 FGFR2; fibroblast growth factor receptor 2 isoform X1 K05093 FGFR2; fibroblast growth factor receptor 2 [EC:2.7.10.1]
C 100141386 FGFR3; fibroblast growth factor receptor 3 isoform X1 K05094 FGFR3; fibroblast growth factor receptor 3 [EC:2.7.10.1]
C 101100864 FGFR4; fibroblast growth factor receptor 4 isoform X5 K05095 FGFR4; fibroblast growth factor receptor 4 [EC:2.7.10.1]
B VEGFR family [OT]
C 101088292 FLT1; vascular endothelial growth factor receptor 1 isoform X2 K05096 FLT1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]
C 101094727 FLT4; vascular endothelial growth factor receptor 3 isoform X3 K05097 FLT4; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
C 101090260 KDR; vascular endothelial growth factor receptor 2 K05098 KDR; kinase insert domain protein receptor [EC:2.7.10.1]
B MET family
C 493669 MET; hepatocyte growth factor receptor precursor K05099 MET; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
C 101089993 MST1R; macrophage-stimulating protein receptor isoform X5 K05100 MST1R; macrophage-stimulating 1 receptor [EC:2.7.10.1]
B TRK family [OT]
C 101081603 NTRK1; high affinity nerve growth factor receptor K03176 NTRK1; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
C 101101347 NTRK2; BDNF/NT-3 growth factors receptor isoform X1 K04360 NTRK2; neurotrophic tyrosine kinase receptor type 2 [EC:2.7.10.1]
C 101085548 NTRK3; NT-3 growth factor receptor isoform X4 K05101 NTRK3; neurotrophic tyrosine kinase, receptor type 3 [EC:2.7.10.1]
B EPH family [OT]
C 101100200 EPHA1; ephrin type-A receptor 1 isoform X1 K05102 EPHA1; Eph receptor A1 [EC:2.7.10.1]
C 101085481 EPHA2; ephrin type-A receptor 2 K05103 EPHA2; Eph receptor A2 [EC:2.7.10.1]
C 101085310 EPHA3; ephrin type-A receptor 3 isoform X1 K05104 EPHA3; Eph receptor A3 [EC:2.7.10.1]
C 101081155 EPHA4; ephrin type-A receptor 4 isoform X1 K05105 EPHA4; Eph receptor A4 [EC:2.7.10.1]
C 101080281 EPHA5; ephrin type-A receptor 5 isoform X1 K05106 EPHA5; Eph receptor A5 [EC:2.7.10.1]
C 101087597 EPHA6; ephrin type-A receptor 6 isoform X1 K05107 EPHA6; Eph receptor A6 [EC:2.7.10.1]
C 101100306 EPHA7; ephrin type-A receptor 7 isoform X1 K05108 EPHA7; EphA7 [EC:2.7.10.1]
C 101095669 EPHA8; ephrin type-A receptor 8 K05109 EPHA8; Eph receptor A8 [EC:2.7.10.1]
C 101091797 EPHA10; ephrin type-A receptor 10 K08897 EPHA10; Eph receptor A10 [EC:2.7.10.1]
C 101086086 EPHB1; ephrin type-B receptor 1 isoform X2 K05110 EPHB1; Eph receptor B1 [EC:2.7.10.1]
C 101095030 EPHB2; ephrin type-B receptor 2 isoform X3 K05111 EPHB2; Eph receptor B2 [EC:2.7.10.1]
C 101094200 EPHB3; ephrin type-B receptor 3 isoform X4 K05112 EPHB3; Eph receptor B3 [EC:2.7.10.1]
C 101094226 EPHB4; ephrin type-B receptor 4 isoform X1 K05113 EPHB4; Eph receptor B4 [EC:2.7.10.1]
C 101085965 EPHB6; ephrin type-B receptor 6 isoform X1 K05114 EPHB6; Eph receptor B6 [EC:2.7.10.1]
B AXL family
C 101086688 AXL; tyrosine-protein kinase receptor UFO isoform X1 K05115 AXL; AXL receptor tyrosine kinase [EC:2.7.10.1]
C 101083854 TYRO3; tyrosine-protein kinase receptor TYRO3 isoform X1 K05116 TYRO3; TYRO3 protein tyrosine kinase 3 [EC:2.7.10.1]
C 101084099 MERTK; tyrosine-protein kinase Mer isoform X1 K05117 MERTK; c-mer proto-oncogene tyrosine kinase [EC:2.7.10.1]
B ALK family
C 101091689 ALK; ALK tyrosine kinase receptor isoform X1 K05119 ALK; anaplastic lymphoma kinase [EC:2.7.10.1]
C 123386239 LTK; LOW QUALITY PROTEIN: leukocyte tyrosine kinase receptor K05118 LTK; leukocyte tyrosine kinase [EC:2.7.10.1]
B TIE family
C 101080986 TIE1; tyrosine-protein kinase receptor Tie-1 K05120 TIE1; tyrosine kinase receptor 1 [EC:2.7.10.1]
C 101091977 TEK; angiopoietin-1 receptor isoform X1 K05121 TEK; endothelial-specific receptor tyrosine kinase [EC:2.7.10.1]
B ROR family
C 101100987 ROR1; inactive tyrosine-protein kinase transmembrane receptor ROR1 isoform X1 K05122 ROR1; receptor tyrosine kinase-like orphan receptor 1 [EC:2.7.10.1]
C 101087689 ROR2; tyrosine-protein kinase transmembrane receptor ROR2 isoform X2 K05123 ROR2; receptor tyrosine kinase-like orphan receptor 2 [EC:2.7.10.1]
B DDR family
C 101096728 DDR1; epithelial discoidin domain-containing receptor 1 isoform X1 K05124 DDR1; discoidin domain receptor family member 1 [EC:2.7.10.1]
C 101085267 DDR2; discoidin domain-containing receptor 2 isoform X1 K05125 DDR2; discoidin domain receptor family member 2 [EC:2.7.10.1]
B RET family
C 101101086 RET; proto-oncogene tyrosine-protein kinase receptor Ret K05126 RET; proto-oncogene tyrosine-protein kinase Ret [EC:2.7.10.1]
B ROS family
C 101093437 ROS1; proto-oncogene tyrosine-protein kinase ROS isoform X1 K05088 ROS1; proto-oncogene tyrosine-protein kinase ROS [EC:2.7.10.1]
B CCK family
C 101093606 PTK7; inactive tyrosine-protein kinase 7 isoform X1 K05127 PTK7; PTK7 protein tyrosine kinase 7 [EC:2.7.10.1]
B RYK family
C 101086838 RYK; tyrosine-protein kinase RYK isoform X1 K05128 RYK; RYK receptor-like tyrosine kinase [EC:2.7.10.1]
B MUSK family
C 101092154 MUSK; muscle, skeletal receptor tyrosine-protein kinase isoform X2 K05129 MUSK; muscle, skeletal, receptor tyrosine kinase [EC:2.7.10.1]
B LMR family [OT]
C 101095933 AATK; serine/threonine-protein kinase LMTK1 isoform X6 K17480 AATK; lemur tyrosine kinase 1 [EC:2.7.10.1]
C 101097774 LMTK2; serine/threonine-protein kinase LMTK2 isoform X1 K08898 LMTK2; lemur tyrosine kinase 2 [EC:2.7.10.1]
C 101087117 LMTK3; LOW QUALITY PROTEIN: serine/threonine-protein kinase LMTK3 K08899 LMTK3; lemur tyrosine kinase 3 [EC:2.7.10.1]
#
ANon-receptor tyrosine kinases
B ABL family
C 101087622 ABL1; tyrosine-protein kinase ABL1 isoform X1 K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
C 101080757 ABL2; tyrosine-protein kinase ABL2 isoform X1 K08887 ABL2; abelson tyrosine-protein kinase 2 [EC:2.7.10.2]
B ACK family
C 101096181 TNK1; non-receptor tyrosine-protein kinase TNK1 K08885 TNK1; non-receptor tyrosine-protein kinase TNK1 [EC:2.7.10.2]
C 101098817 TNK2; activated CDC42 kinase 1 isoform X16 K08886 TNK2; activated CDC42 kinase 1 [EC:2.7.10.2 2.7.11.1]
B CSK family
C 101083340 CSK; tyrosine-protein kinase CSK K05728 CSK; c-src tyrosine kinase [EC:2.7.10.2]
C 101099024 MATK; megakaryocyte-associated tyrosine-protein kinase isoform X1 K08888 MATK; megakaryocyte-associated tyrosine kinase [EC:2.7.10.2]
B FAK family
C 101095952 PTK2; focal adhesion kinase 1 isoform X1 K05725 PTK2; focal adhesion kinase 1 [EC:2.7.10.2]
C 101091691 PTK2B; protein-tyrosine kinase 2-beta isoform X2 K05871 PTK2B; focal adhesion kinase 2 [EC:2.7.10.2]
B FES family
C 101100568 FES; tyrosine-protein kinase Fes/Fps isoform X1 K07527 FES; tyrosine-protein kinase Fes/Fps [EC:2.7.10.2]
C 101094235 FER; tyrosine-protein kinase Fer isoform X1 K08889 FER; tyrosine-protein kinase Fer [EC:2.7.10.2]
B JAK family [OT]
C 101084377 JAK1; tyrosine-protein kinase JAK1 K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
C 101088959 JAK2; tyrosine-protein kinase JAK2 isoform X3 K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
C 101092339 JAK3; tyrosine-protein kinase JAK3 K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
C 101090171 TYK2; non-receptor tyrosine-protein kinase TYK2 isoform X1 K11219 TYK2; non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]
B SRC family
C 101084104 BLK; tyrosine-protein kinase Blk K08890 BLK; B lymphoid tyrosine kinase [EC:2.7.10.2]
C 101083781 FGR; tyrosine-protein kinase Fgr K08891 FGR; tyrosine-protein kinase Fgr [EC:2.7.10.2]
C 101088668 FRK; tyrosine-protein kinase FRK K08892 FRK; fyn-related kinase [EC:2.7.10.2]
C 101085720 FYN; LOW QUALITY PROTEIN: tyrosine-protein kinase Fyn K05703 FYN; tyrosine-protein kinase Fyn [EC:2.7.10.2]
C 101101207 HCK; tyrosine-protein kinase HCK K08893 HCK; hemopoietic cell kinase [EC:2.7.10.2]
C 101096633 LYN; tyrosine-protein kinase Lyn isoform X3 K05854 LYN; tyrosine-protein kinase Lyn [EC:2.7.10.2]
C 101098805 LCK; tyrosine-protein kinase Lck isoform X2 K05856 LCK; lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2]
C 101100294 PTK6; protein-tyrosine kinase 6 isoform X6 K08894 PTK6; protein tyrosine kinase 6 [EC:2.7.10.2]
C 101100378 SRC; proto-oncogene tyrosine-protein kinase Src isoform X3 K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
C 101100042 SRMS; tyrosine-protein kinase Srms isoform X2 K08895 SRMS; tyrosine-protein kinase Srms [EC:2.7.10.2]
C 101090724 YES1; tyrosine-protein kinase Yes K05705 YES1; tyrosine-protein kinase Yes [EC:2.7.10.2]
B TEC family
C 101095795 BMX; cytoplasmic tyrosine-protein kinase BMX isoform X4 K08896 BMX; cytoplasmic tyrosine-protein kinase BMX [EC:2.7.10.2]
C 101088062 BTK; tyrosine-protein kinase BTK K07370 BTK; Bruton agammaglobulinemia tyrosine kinase [EC:2.7.10.2]
C 101100785 ITK; tyrosine-protein kinase ITK/TSK K07363 ITK; IL2-inducible T-cell kinase [EC:2.7.10.2]
C 101095493 TEC; tyrosine-protein kinase Tec isoform X1 K07364 TEC; tyrosine-protein kinase Tec [EC:2.7.10.2]
C 101095739 TXK; tyrosine-protein kinase TXK isoform X2 K08016 TXK; tyrosine-protein kinase TXK [EC:2.7.10.2]
B SYK family
C 101087013 SYK; tyrosine-protein kinase SYK isoform X1 K05855 SYK; spleen tyrosine kinase [EC:2.7.10.2]
C 101097059 ZAP70; tyrosine-protein kinase ZAP-70 isoform X2 K07360 ZAP70; tyrosine-protein kinase ZAP-70 [EC:2.7.10.2]
B Other
C 101088762 STYK1; tyrosine-protein kinase STYK1 K17510 STYK1; tyrosine-protein kinase STYK1 [EC:2.7.10.2]
C 101094841 PKDCC; extracellular tyrosine-protein kinase PKDCC isoform X1 K17548 PKDCC; extracellular tyrosine-protein kinase PKDCC [EC:2.7.10.2]
B Bacterial
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AHistidine kinases
B OmpR family
B NarL family
B Spo family [OT]
B CitB family [OT]
B LytTR family [OT]
B NtrC family
B CheA family [OT]
B Cell cycle family [OT]
B Lux family [OT]
B LuxR family [OT]
B Other
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: April 2, 2024
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Classification taken and modified from Hanks (2003)