+D Messenger RNA Biogenesis KO
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Prokaryotic Defense System - Candidatus Hamiltonella defensa (Acyrthosiphon pisum)
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ACRISPR-Cas system
B Universal Cas proteins
B Type I CRISPR-Cas system
C Type I signiture cas proteins
C Subtype I-A factors
C Subtype I-B factors
C Subtype I-C factors
C Subtype I-D factors
C Subtype I-E factors
C Subtype I-F factors
C Subtype I-U factors
B Type II CRISPR-Cas system
C Type II signiture cas proteins
C Subtype II-A factors
C Subtype II-B factors
B Type III CRISPR-Cas system
C Type III signiture cas proteins
C Subtype III-A factors
C Subtype III-B factors
C Subtype III-U factors
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ARestriction and modification system (R-M system)
B Type I R-M system
C HDEF_1592 putative restriction endonuclease, N6_Mtase domain protein K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72]
B Type II R-M system
C Restriction endonucleases
C DNA methyltransferases
D HDEF_1639 dam; DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
D HDEF_1005 DNA methylase, N6_N4_Mtase domain protein K07319 yhdJ; adenine-specific DNA-methyltransferase [EC:2.1.1.72]
D HDEF_0909 dcm_1; DNA cytosine methylase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
B Type III R-M system
B Type IV R-M system
C HDEF_2022 group II intron encoded reverse transcriptase K07451 mcrA; 5-methylcytosine-specific restriction enzyme A [EC:3.1.21.-]
C HDEF_2002 group II intron encoded reverse transcriptase K07451 mcrA; 5-methylcytosine-specific restriction enzyme A [EC:3.1.21.-]
C HDEF_1451 conserved hypothetical phage protein K07451 mcrA; 5-methylcytosine-specific restriction enzyme A [EC:3.1.21.-]
C HDEF_1112 phage HNH endonuclease K07451 mcrA; 5-methylcytosine-specific restriction enzyme A [EC:3.1.21.-]
C HDEF_1011 phage HNH endonuclease K07451 mcrA; 5-methylcytosine-specific restriction enzyme A [EC:3.1.21.-]
C HDEF_0981 group II intron encoded reverse transcriptase K07451 mcrA; 5-methylcytosine-specific restriction enzyme A [EC:3.1.21.-]
C HDEF_0745 restriction endonuclease, Mrr_cat domain protein K07448 mrr; restriction system protein
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AToxin-antitoxin system (TA system)
B Type I TA system
C Hok-Sok
C SymE-SymR
C Ldr-Rdl
C TisB-IstR
C Ibs-Sib
C ShoB-OhsC
C RalR-RalA
B Type II TA system
C MazF-MazE
D HDEF_0256 addiction module toxin K07171 mazF; mRNA interferase MazF [EC:3.1.-.-]
C ChpB-ChpS
D HDEF_1393 chpB; addiction module, toxin ChpB K18841 chpB; mRNA interferase ChpB [EC:3.1.-.-]
D HDEF_1394 chpS; addiction module, antitoxin ChpS K18842 chpS; antitoxin ChpS
C YhaV-PrlF
C RelE/StbE-RelB/StbD
D HDEF_1077 addiction module antitoxin K06218 relE; mRNA interferase RelE/StbE
D HDEF_1076 addiction module antitoxin K18918 relB; RHH-type transcriptional regulator, rel operon repressor / antitoxin RelB
C YafQ-dinJ
D HDEF_1448 addiction module toxin K19157 yafQ; mRNA interferase YafQ [EC:3.1.-.-]
D HDEF_1232 addiction module toxin K19157 yafQ; mRNA interferase YafQ [EC:3.1.-.-]
D HDEF_1125 addiction module antitoxin K07473 dinJ; DNA-damage-inducible protein J
D HDEF_1447 addiction module antitoxin K07473 dinJ; DNA-damage-inducible protein J
D HDEF_1233 addiction module antitoxin K07473 dinJ; DNA-damage-inducible protein J
C YoeB-YefM
D HDEF_1085 addiction module toxin K19158 yoeB; toxin YoeB [EC:3.1.-.-]
D HDEF_0110 addiction module toxin K19158 yoeB; toxin YoeB [EC:3.1.-.-]
D HDEF_1086 addiction module antitoxin K19159 yefM; antitoxin YefM
C HipA-HipB
C HicA-HicB
C YafO-YafN
C Hha-TomB
D HDEF_1625 hha; hemolysin expression modulator K05839 hha; haemolysin expression modulating protein
C PspC-PspB
C CcdB-CcdA
C ParE-ParD
D HDEF_p0021 conserved hypothetical protein HDEF_p0021 K19092 parE1_3_4; toxin ParE1/3/4
D HDEF_1121 addiction module K19092 parE1_3_4; toxin ParE1/3/4
C Doc-Phd
C HigB-HigA
D HDEF_1037 hypothetical protein K19166 higB; mRNA interferase HigB [EC:3.1.-.-]
D HDEF_p0026 addiction module, toxin K07334 higB-1; toxin HigB-1
D HDEF_1036 putative transcriptional regulator, HTH_3 domain protein K18831 higA; HTH-type transcriptional regulator / antitoxin HigA
D HDEF_p0028 addiction module, antitoxin K21498 higA-1; antitoxin HigA-1
C MqsR-MqsA
C VapC-VapB
D HDEF_2149 addiction module, PIN domain protein K18828 mvpA; tRNA(fMet)-specific endonuclease VapC [EC:3.1.-.-]
D HDEF_0960 addiction module,PIN domain protein K18828 mvpA; tRNA(fMet)-specific endonuclease VapC [EC:3.1.-.-]
D HDEF_0430 vagD; addiction module, PIN domain protein K18828 mvpA; tRNA(fMet)-specific endonuclease VapC [EC:3.1.-.-]
D HDEF_p0008 putative addiction module, PIN domain protein K18828 mvpA; tRNA(fMet)-specific endonuclease VapC [EC:3.1.-.-]
D HDEF_0961 addiction module, SpoVT/AbrB domain protein K18829 mvpT; antitoxin VapB
D HDEF_0431 vagC; addiction module K18829 mvpT; antitoxin VapB
D HDEF_2150 addiction module, SpoVT/AbrB domain protein K18829 mvpT; antitoxin VapB
C PezT-PezA
C YobL-YobK
C YokI-YokJ
C YqcG-YqcF
C YxiD-YxxD
C FitB-FitA
D HDEF_0261 addiction module, PIN domain protein K07062 fitB; toxin FitB [EC:3.1.-.-]
D HDEF_0976 addiction module, PIN domain protein K07062 fitB; toxin FitB [EC:3.1.-.-]
D HDEF_0427 addiction module, PIN domain protein K07062 fitB; toxin FitB [EC:3.1.-.-]
D HDEF_0260 addiction module K21495 fitA; antitoxin FitA
D HDEF_2169 stbC_2; addiction module K21495 fitA; antitoxin FitA
C BC_0920-BC_0921
C Type II TA system related factors
D HDEF_1778 ftsZ; tubulin-like GTP-binding protein and GTPase, forms circumferential ring in cell division K03531 ftsZ; cell division protein FtsZ
D HDEF_1726 mreB; mecillinam resistance-associated protein K03569 mreB; rod shape-determining protein MreB and related proteins
D HDEF_0801 parC; DNA topoisomerase IV, subunit A K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2]
D HDEF_0799 parE; DNA topoisomerase IV, subunit B K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2]
D HDEF_0366 gltX; glutamate tRNA synthetase, catalytic subunit K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
B Type III TA system
C AbiQ system
B Type IV TA system
C YeeV-YeeU
C CptA-CptB
D HDEF_0559 hypothetical protein K19168 cptA; toxin CptA
D HDEF_0560 hypothetical protein K09159 cptB; antitoxin CptB
B Type V TA system
C GhoT-GhoS
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ADNA phosphothiolation system
B Sulfur modification proteins
C HDEF_0542 iscS; cysteine desulfurase (tRNA sulfurtransferase), PLP-dependent K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
B DNA phosphorothioation-dependent restriction proteins
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: November 7, 2023