+E	Replication protein	KO
#<h2><a href="/kegg/brite.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; DNA Replication Proteins - Haemophilus influenzae F3031 (nontypeable)</h2>
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A<b>Eukaryotic type</b>
B  DNA Replication Initiation Factors
C    pre-RC (pre-replication complex)
C    CDK (cyclin dependent kinase)
C    DDK (Dbf-4 dependent kinase)
C    GINS complex
C    Other initiation factors
B  DNA Replication Elongation Factors
C    DNA polymerase alpha / primase complex
C    DNA polymerase epsilon complex
C    DNA polymerase delta complex
C    DNA polymerase gamma complex (mitochondrial)
C    RPA (replication protein A)
C    RFC (replication factor C)
C    RNase H
D      HIBPF_19620 ribonuclease HI	K03469 rnhA; ribonuclease HI [EC:3.1.26.4] 
C    Other elongation factors
B  DNA Replication Termination Factors
C    DNA methylation enzymes
D      HIBPF_04320 Cytosine-specific methyltransferase	K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] 
D      HIBPF_07341 haeIIIM; Modification methylase HaeIII	K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] 
C    Prevention of re-replication factors
C    Telomere proteins
D      Shelterin complex
D      TERB1-TERB2-MAJIN complex
D      CST complex (animals)
D      CST complex (yeast)
D      RIF proteins
D      SIR proteins
C    Telomerase complex (animals)
D      Dyskerin complex
C    Telomerase complex (fungi)
D      Sm core complex
C    ELG1-RFC complex
C    MRN complex
C    Other termination factors
B  DNA Topoisomerases
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A<b>Prokaryotic type</b>
B  DNA Replication Initiation Factors
C    Initiation factors (bacterial)
D      HIBPF_19020 DNA-binding protein HU	K05787 hupA; DNA-binding protein HU-alpha 
D      HIBPF_08380 integration host factor (IHF), DNA-binding protein, alpha subunit	K04764 ihfA; integration host factor subunit alpha 
D      HIBPF_05970 Integration host factor beta-subunit	K05788 ihfB; integration host factor subunit beta 
D      HIBPF_12540 chromosomal replication initiator protein DnaA,DNA-binding transcriptional dual regulator	K02313 dnaA; chromosomal replication initiator protein 
D      HIBPF_09790 replicative DNA helicase	K02314 dnaB; replicative DNA helicase [EC:5.6.2.3] 
D      HIBPF_17970 DNA primase	K02316 dnaG; DNA primase [EC:2.7.7.101] 
D      HIBPF_04270 single-stranded DNA-binding protein	K03111 ssb; single-strand DNA-binding protein 
D      HIBPF_01940 ssb; Single-stranded DNA-binding protein	K03111 ssb; single-strand DNA-binding protein 
D      HIBPF_09750 ssb3; Single-strand binding protein	K03111 ssb; single-strand DNA-binding protein 
C    Initiation factors (archaeal)
B  DNA Replication Elongation Factors
C    Elongation factors (bacterial)
D      DNA polymerase III holoenzyme
E        HIBPF_15670 DNA polymerase III alpha subunit	K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] 
E        HIBPF_12550 DNA polymerase III, beta subunit	K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] 
E        HIBPF_07640 DNA polymerase III, chi subunit	K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7] 
E        HIBPF_13880 DNA polymerase III, delta subunit	K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] 
E        HIBPF_18750 DNA polymerase III, delta prime subunit	K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7] 
E        HIBPF_19610 DNA polymerase III epsilon subunit	K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] 
E        HIBPF_06050 DNA polymerase III/DNA elongation factor III, tau and gamma subunits	K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] 
E        HIBPF_00110 DNA polymerase III, psi subunit	K02344 holD; DNA polymerase III subunit psi [EC:2.7.7.7] 
D      RNase H
E        HIBPF_19620 ribonuclease HI	K03469 rnhA; ribonuclease HI [EC:3.1.26.4] 
E        HIBPF_12070 ribonuclease HII, degrades RNA of DNA-RNA hybrids	K03470 rnhB; ribonuclease HII [EC:3.1.26.4] 
D      Other elongation factors
E        HIBPF_14520 DNA polymerase I	K02335 polA; DNA polymerase I [EC:2.7.7.7] 
E        HIBPF_11680 ligA; DNA ligase, NAD(+)-dependent	K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] 
C    Elongation factors (archaeal)
D      B-family DNA polymerases
D      D-family DNA polymerases
D      RNase H
E        HIBPF_19620 ribonuclease HI	K03469 rnhA; ribonuclease HI [EC:3.1.26.4] 
E        HIBPF_12070 ribonuclease HII, degrades RNA of DNA-RNA hybrids	K03470 rnhB; ribonuclease HII [EC:3.1.26.4] 
D      RFC (replication factor C)
D      Other elongation factors
B  DNA Replication Termination Factors
C    Terminus site-binding protein
C    DNA methylation enzymes
D      HIBPF_20400 DNA adenine methylase	K06223 dam; DNA adenine methylase [EC:2.1.1.72] 
D      HIBPF_18010 putative adenine-specific DNA methylase	K06223 dam; DNA adenine methylase [EC:2.1.1.72] 
C    Prevention of re-replication factors
D      HIBPF_20240 SeqA regulatory protein for replication initiation	K03645 seqA; negative modulator of initiation of replication 
D      HIBPF_06020 ATPase regulatory factor involved in DnaA inactivation	K10763 hda; DnaA-homolog protein 
B  DNA Topoisomerases
C    HIBPF_06490 DNA gyrase (type II topoisomerase), subunit A	K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2] 
C    HIBPF_17610 DNA gyrase, subunit B	K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2] 
C    HIBPF_08760 DNA topoisomerase IV, subunit A	K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2] 
C    HIBPF_08750 DNA topoisomerase IV, subunit B	K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2] 
C    HIBPF_07230 DNA topoisomerase I, omega subunit	K03168 topA; DNA topoisomerase I [EC:5.6.2.1] 
C    HIBPF_18880 DNA topoisomerase III	K03169 topB; DNA topoisomerase III [EC:5.6.2.1] 
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#Last updated: November 2, 2022