+E Proteasome KO
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Proteasome - Homo sapiens (human)
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AEukaryotic proteasome
B Core particles (20S proteasome)
C alpha type subunits
D 5687 PSMA6; proteasome 20S subunit alpha 6 K02730 PSMA6; 20S proteasome subunit alpha 1 [EC:3.4.25.1]
D 5683 PSMA2; proteasome 20S subunit alpha 2 K02726 PSMA2; 20S proteasome subunit alpha 2 [EC:3.4.25.1]
D 5685 PSMA4; proteasome 20S subunit alpha 4 K02728 PSMA4; 20S proteasome subunit alpha 3 [EC:3.4.25.1]
D 5688 PSMA7; proteasome 20S subunit alpha 7 K02731 PSMA7; 20S proteasome subunit alpha 4 [EC:3.4.25.1]
D 143471 PSMA8; proteasome 20S subunit alpha 8 K02731 PSMA7; 20S proteasome subunit alpha 4 [EC:3.4.25.1]
D 5686 PSMA5; proteasome 20S subunit alpha 5 K02729 PSMA5; 20S proteasome subunit alpha 5 [EC:3.4.25.1]
D 5682 PSMA1; proteasome 20S subunit alpha 1 K02725 PSMA1; 20S proteasome subunit alpha 6 [EC:3.4.25.1]
D 5684 PSMA3; proteasome 20S subunit alpha 3 K02727 PSMA3; 20S proteasome subunit alpha 7 [EC:3.4.25.1]
C beta type subunits
D 5694 PSMB6; proteasome 20S subunit beta 6 K02738 PSMB6; 20S proteasome subunit beta 1 [EC:3.4.25.1]
D 5695 PSMB7; proteasome 20S subunit beta 7 K02739 PSMB7; 20S proteasome subunit beta 2 [EC:3.4.25.1]
D 5691 PSMB3; proteasome 20S subunit beta 3 K02735 PSMB3; 20S proteasome subunit beta 3 [EC:3.4.25.1]
D 5690 PSMB2; proteasome 20S subunit beta 2 K02734 PSMB2; 20S proteasome subunit beta 4 [EC:3.4.25.1]
D 5693 PSMB5; proteasome 20S subunit beta 5 K02737 PSMB5; 20S proteasome subunit beta 5 [EC:3.4.25.1]
D 5689 PSMB1; proteasome 20S subunit beta 1 K02732 PSMB1; 20S proteasome subunit beta 6 [EC:3.4.25.1]
D 5692 PSMB4; proteasome 20S subunit beta 4 K02736 PSMB4; 20S proteasome subunit beta 7 [EC:3.4.25.1]
D 5696 PSMB8; proteasome 20S subunit beta 8 K02740 PSMB8; 20S proteasome subunit beta 8 [EC:3.4.25.1]
D 5698 PSMB9; proteasome 20S subunit beta 9 K02741 PSMB9; 20S proteasome subunit beta 9 [EC:3.4.25.1]
D 5699 PSMB10; proteasome 20S subunit beta 10 K02733 PSMB10; 20S proteasome subunit beta 10 [EC:3.4.25.1]
D 122706 PSMB11; proteasome subunit beta 11 K11598 PSMB11; 20S proteasome subunit beta 11 [EC:3.4.25.1]
B Regulatory particles
C PA700 (19S proteasome)
D ATPase subunits
E 5701 PSMC2; proteasome 26S subunit, ATPase 2 K03061 PSMC2; 26S proteasome regulatory subunit T1
E 5700 PSMC1; proteasome 26S subunit, ATPase 1 K03062 PSMC1; 26S proteasome regulatory subunit T2
E 5704 PSMC4; proteasome 26S subunit, ATPase 4 K03063 PSMC4; 26S proteasome regulatory subunit T3
E 5706 PSMC6; proteasome 26S subunit, ATPase 6 K03064 PSMC6; 26S proteasome regulatory subunit T4
E 5702 PSMC3; proteasome 26S subunit, ATPase 3 K03065 PSMC3; 26S proteasome regulatory subunit T5
E 5705 PSMC5; proteasome 26S subunit, ATPase 5 K03066 PSMC5; 26S proteasome regulatory subunit T6
D non-ATPase subunits
E 5708 PSMD2; proteasome 26S subunit ubiquitin receptor, non-ATPase 2 K03028 PSMD2; 26S proteasome regulatory subunit N1
E 5707 PSMD1; proteasome 26S subunit, non-ATPase 1 K03032 PSMD1; 26S proteasome regulatory subunit N2
E 5709 PSMD3; proteasome 26S subunit, non-ATPase 3 K03033 PSMD3; 26S proteasome regulatory subunit N3
E 5715 PSMD9; proteasome 26S subunit, non-ATPase 9 K06693 PSMD9; 26S proteasome regulatory subunit N4
E 5718 PSMD12; proteasome 26S subunit, non-ATPase 12 K03035 PSMD12; 26S proteasome regulatory subunit N5
E 5717 PSMD11; proteasome 26S subunit, non-ATPase 11 K03036 PSMD11; 26S proteasome regulatory subunit N6
E 9861 PSMD6; proteasome 26S subunit, non-ATPase 6 K03037 PSMD6; 26S proteasome regulatory subunit N7
E 5713 PSMD7; proteasome 26S subunit, non-ATPase 7 K03038 PSMD7; 26S proteasome regulatory subunit N8
E 5719 PSMD13; proteasome 26S subunit, non-ATPase 13 K03039 PSMD13; 26S proteasome regulatory subunit N9
E 5710 PSMD4; proteasome 26S subunit ubiquitin receptor, non-ATPase 4 K03029 PSMD4; 26S proteasome regulatory subunit N10
E 10213 PSMD14; proteasome 26S subunit, non-ATPase 14 K03030 PSMD14; 26S proteasome regulatory subunit N11
E 5714 PSMD8; proteasome 26S subunit, non-ATPase 8 K03031 PSMD8; 26S proteasome regulatory subunit N12
E 11047 ADRM1; ADRM1 26S proteasome ubiquitin receptor K06691 RPN13; 26S proteasome regulatory subunit N13
E 7979 SEM1; SEM1 26S proteasome subunit K10881 SHFM1; 26 proteasome complex subunit DSS1
E 5711 PSMD5; proteasome 26S subunit, non-ATPase 5 K06692 PSMD5; 26S proteasome non-ATPase regulatory subunit 5
E 5716 PSMD10; proteasome 26S subunit, non-ATPase 10 K06694 PSMD10; 26S proteasome non-ATPase regulatory subunit 10
C PA28 (11S REG)
D 5720 PSME1; proteasome activator subunit 1 K06696 PSME1; proteasome activator subunit 1 (PA28 alpha)
D 5721 PSME2; proteasome activator subunit 2 K06697 PSME2; proteasome activator subunit 2 (PA28 beta)
D 10197 PSME3; proteasome activator subunit 3 K06698 PSME3; proteasome activator subunit 3 (PA28 gamma)
C PA200
D 23198 PSME4; proteasome activator subunit 4 K06699 PSME4; proteasome activator subunit 4
C PI31
D 9491 PSMF1; proteasome inhibitor subunit 1 K06700 PSMF1; proteasome inhibitor subunit 1 (PI31)
B Assembling factors
C Assembling chaperones
D 51371 POMP; proteasome maturation protein K11599 POMP; proteasome maturation protein
D 8624 PSMG1; proteasome assembly chaperone 1 K11875 PSMG1; proteasome assembly chaperone 1
D 56984 PSMG2; proteasome assembly chaperone 2 K11876 PSMG2; proteasome assembly chaperone 2
D 84262 PSMG3; proteasome assembly chaperone 3 K11877 PSMG3; proteasome assembly chaperone 3
D 389362 PSMG4; proteasome assembly chaperone 4 K11878 PSMG4; proteasome assembly chaperone 4
C Other assembling factors
D 3646 EIF3E; eukaryotic translation initiation factor 3 subunit E K03250 EIF3E; translation initiation factor 3 subunit E
D 3312 HSPA8; heat shock protein family A (Hsp70) member 8 K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D 3303 HSPA1A; heat shock protein family A (Hsp70) member 1A K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D 3305 HSPA1L; heat shock protein family A (Hsp70) member 1 like K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D 3304 HSPA1B; heat shock protein family A (Hsp70) member 1B K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D 3310 HSPA6; heat shock protein family A (Hsp70) member 6 K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D 3306 HSPA2; heat shock protein family A (Hsp70) member 2 K26598 HSPA2; heat shock 70kDa protein 2
D 3320 HSP90AA1; heat shock protein 90 alpha family class A member 1 K04079 HSP90A; molecular chaperone HtpG
D 3326 HSP90AB1; heat shock protein 90 alpha family class B member 1 K04079 HSP90A; molecular chaperone HtpG
D 3458 IFNG; interferon gamma K04687 IFNG; interferon gamma
D 28987 NOB1; NIN1 (RPN12) binding protein 1 homolog K11883 NOB1; RNA-binding protein NOB1
D 56902 PNO1; partner of NOB1 homolog K11884 PNO1; RNA-binding protein PNO1
B Proteasome interacting proteins (PIPs)
C UBL-UBA shuttle proteins
D 5887 RAD23B; RAD23 homolog B, nucleotide excision repair protein K10839 RAD23; UV excision repair protein RAD23
D 5886 RAD23A; RAD23 homolog A, nucleotide excision repair protein K10839 RAD23; UV excision repair protein RAD23
D 29979 UBQLN1; ubiquilin 1 K04523 UBQLN; ubiquilin
D 29978 UBQLN2; ubiquilin 2 K04523 UBQLN; ubiquilin
D 50613 UBQLN3; ubiquilin 3 K04523 UBQLN; ubiquilin
D 56893 UBQLN4; ubiquilin 4 K04523 UBQLN; ubiquilin
D 143630 UBQLNL; ubiquilin like K22254 UBQLNL; ubiquilin-like protein
D 414301 DDI1; DNA damage inducible 1 homolog 1 K11885 DDI1; DNA damage-inducible protein 1
D 84301 DDI2; DNA damage inducible 1 homolog 2 K11885 DDI1; DNA damage-inducible protein 1
C Other PIPs
D 23392 ECPAS; Ecm29 proteasome adaptor and scaffold K11886 ECM29; proteasome component ECM29
D 80227 PAAF1; proteasomal ATPase associated factor 1 K11887 PAAF1; proteasomal ATPase-associated factor 1
D 29893 PSMC3IP; PSMC3 interacting protein K06695 PSMC3IP; 26S proteasome regulatory subunit, ATPase 3, interacting protein
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AProkaryotic proteasome
B Core particles (20S proteasome)
B Bacterial regulatory particles
B Archaeal regulatory particles
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: June 26, 2023