+D Protein KO
#
Membrane Trafficking - Leishmania donovani
%
!
AExocytosis
B Calcium ion-dependent exocytosis
C Synaptotagmins
C Septins
C DOC-2 proteins
C Acrosomal exocytosis proteins
C Phospholipases
D LDBPK_302970 phospholipase C-like protein K05857 PLCD; phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]
D LDBPK_221530 phosphoinositide-specific phospholipase C, putative K05857 PLCD; phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]
C Kinases and associated proteins
D LDBPK_044320 hypothetical protein K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
D LDBPK_353910 nucleoside diphosphate kinase, putative K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
D LDBPK_323110 nucleoside diphosphate kinase B K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
C Others
B Small GTPases and associated proteins
C Rab GTPases
C Rab associated proteins
D LDBPK_090970 calmodulin, putative K02183 CALM; calmodulin
D LDBPK_090980 calmodulin, putative K02183 CALM; calmodulin
D LDBPK_210280 calmodulin-like protein K02183 CALM; calmodulin
D LDBPK_280860 calmodulin-like protein K02183 CALM; calmodulin
D LDBPK_353930 calmodulin-like protein K02183 CALM; calmodulin
D LDBPK_131060 calmodulin, putative K02183 CALM; calmodulin
D LDBPK_262270 syntaxin binding protein 1, putative K15292 STXBP1; syntaxin-binding protein 1
D LDBPK_351800 trypanin-like protein K19942 GAS8; dynein regulatory complex subunit 4
D LDBPK_151210 inositol/phosphatidylinositol phosphatase, putative K01099 INPP5B_F; inositol polyphosphate 5-phosphatase INPP5B/F [EC:3.1.3.36]
D LDBPK_351430 peroxisome targeting signal 1 receptor, putative K13342 PEX5; peroxin-5
D LDBPK_343860 geranylgeranyltransferase, putative K05956 RABGGTB; geranylgeranyl transferase type-2 subunit beta [EC:2.5.1.60]
C Rho GTPases
C Other small GTPases and associated proteins
B Tethering complex
C Exocyst complex
C Exocyst complex assembly proteins
B Others
C Exomer complex
C Others
D LDBPK_354850 hypothetical protein K19995 SCAMP; secretory carrier-associated membrane protein
#
ASNARE
B Syntaxin (Qa)
C Stx-PM
D LDBPK_281600 Qa-SNARE protein K08486 STX1B_2_3; syntaxin 1B/2/3
D LDBPK_364840 hypothetical protein K08486 STX1B_2_3; syntaxin 1B/2/3
C Stx-Endo
C Stx-TGN / EE
D LDBPK_331420 QA-SNARE protein putative K08489 STX16; syntaxin 16
D LDBPK_352760 QA-SNARE protein putative K08489 STX16; syntaxin 16
C Stx-cisGolgi
D LDBPK_320070 Qa-SNARE protein K08490 STX5; syntaxin 5
C Stx-sER
C Stx-rER
B SNAP-25[N] (Qb)
C Vti1
D LDBPK_231790 hypothetical protein K08493 VTI1; vesicle transport through interaction with t-SNAREs 1
D LDBPK_231800 hypothetical protein K08493 VTI1; vesicle transport through interaction with t-SNAREs 1
C NPSN
C Gos1 (Gos28)
D LDBPK_364220 golgi SNARE protein-like protein K08495 GOSR1; golgi SNAP receptor complex member 1
C Bos1 / Membrin
D LDBPK_190770 SNARE protein, putative K08496 GOSR2; golgi SNAP receptor complex member 2
C Sec20
B SNAP-25[C] (Qc)
C STX6
D LDBPK_210620 hypothetical protein K08499 TLG1; member of the syntaxin family of t-SNAREs
C STX8
C STX10
C Bet1
D LDBPK_250090 hypothetical protein K08504 BET1; blocked early in transport 1
D LDBPK_290660 BET1-like protein, putative K08504 BET1; blocked early in transport 1
C Sft1
C Syp7
D LDBPK_210080 syntaxin, putative K08506 SYP7; syntaxin of plants SYP7
D LDBPK_190010 hypothetical protein K08506 SYP7; syntaxin of plants SYP7
D LDBPK_060850 hypothetical protein K08506 SYP7; syntaxin of plants SYP7
C Use1
B SNAP-25 (Qb,c)
C SNAP-23
C SNAP-25
C SNAP-29
C SNAP-47
B VAMP, Ykt6, Sec22 (R)
C VAMP
D LDBPK_211530 vesicule-associated membrane protein, putative K08515 VAMP7; vesicle-associated membrane protein 7
D LDBPK_080030 vesicle-associated membrane protein, putative K08515 VAMP7; vesicle-associated membrane protein 7
D LDBPK_272300 vesicle-associated membrane protein (vamp), putative K08515 VAMP7; vesicle-associated membrane protein 7
C Ykt6
D LDBPK_352150 vesicle-associated membrane protein, putative K08516 YKT6; synaptobrevin homolog YKT6
C Sec22
D LDBPK_190400 synaptobrevin-type transport protein, putative K08517 SEC22; vesicle transport protein SEC22
C Tomosyn
C Putative SNAREs
B SNARE associated proteins
C Syntaxin-binding proteins
D LDBPK_262270 syntaxin binding protein 1, putative K15292 STXBP1; syntaxin-binding protein 1
D LDBPK_262380 sec1 family transport protein, putative K19998 SCFD1; sec1 family domain-containing protein 1
C Palmitoyltransferases
D LDBPK_231690 hypothetical protein K20028 ZDHHC2_15_20; palmitoyltransferase ZDHHC2/15/20 [EC:2.3.1.225]
D LDBPK_231700 DHHC zinc finger domain-like protein K20028 ZDHHC2_15_20; palmitoyltransferase ZDHHC2/15/20 [EC:2.3.1.225]
C Others
D LDBPK_200820 vesicle-fusing ATPase, putative K06027 NSF; vesicle-fusing ATPase [EC:3.6.4.6]
D LDBPK_201660 soluble N-ethylmaleimide sensitive factor, putative K15296 NAPA; alpha-soluble NSF attachment protein
D LDBPK_323040 hypothetical protein K15296 NAPA; alpha-soluble NSF attachment protein
D LDBPK_361420 Transitional endoplasmic reticulum ATPase, putative K13525 VCP; transitional endoplasmic reticulum ATPase
#
AEndocytosis
B Clathrin-mediated endocytosis
C Clathrin
D LDBPK_361700 clathrin heavy chain, putative K04646 CLTC; clathrin heavy chain
C Dynamin
D LDBPK_292310 GTP-binding protein, putative K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
C AP-2 complex
D LDBPK_070060 alpha-adaptin-like protein K11824 AP2A; AP-2 complex subunit alpha
D LDBPK_363180 clathrin coat assembly protein-like protein K11826 AP2M1; AP-2 complex subunit mu-1
D LDBPK_342100 clathrin coat assembly protein AP17, putative K11827 AP2S1; AP-2 complex subunit sigma-1
C Other core components
D LDBPK_250680 epsin, putative K12471 EPN; epsin
D LDBPK_283000 heat-shock protein hsp70, putative K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D LDBPK_283040 heat shock protein 70, putative K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D LDBPK_261220 heat shock protein 70-related protein K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
C Low-density lipoprotein receptor (LDLR) family proteins
C LDLR adaptor proteins
D LDBPK_044320 hypothetical protein K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
C GPCR adaptor proteins
C Receptor tyrosine kinase (RTK) adaptor proteins
C Inositol 5-phosphatases
D LDBPK_151210 inositol/phosphatidylinositol phosphatase, putative K01099 INPP5B_F; inositol polyphosphate 5-phosphatase INPP5B/F [EC:3.1.3.36]
C Kinases
D LDBPK_150180 serine/threonine-protein kinase, putative K08825 DYRK1; dual specificity tyrosine-phosphorylation-regulated kinase 1 [EC:2.7.12.1]
D LDBPK_140890 protein kinase, putative K08825 DYRK1; dual specificity tyrosine-phosphorylation-regulated kinase 1 [EC:2.7.12.1]
C Ubiquitin E3 ligases
C Others
B Lipid raft mediated endocytosis
C Caveolin-mediated endocytosis
D LDBPK_292310 GTP-binding protein, putative K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
C Flotillin-dependent endocytosis
C GRAF1-dependent endocytosis
D LDBPK_312350 ADP-ribosylation factor, putative K07937 ARF1_2; ADP-ribosylation factor 1/2
D LDBPK_040470 ADP-ribosylation factor, putative K07937 ARF1_2; ADP-ribosylation factor 1/2
D LDBPK_312890 ADP-ribosylation factor, putative K07937 ARF1_2; ADP-ribosylation factor 1/2
C Arf6-dependent endocytosis
C RhoA-dependent endocytosis
D LDBPK_292310 GTP-binding protein, putative K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
B Phagocytosis
C Fc receptors
C Integrins (complement receptors)
C Opsonins
C Toll-like receptors
C C-lectin receptors
C Scavenger receptors
C Coronins
C Others
D LDBPK_341070 myosin IB heavy chain, putative K10356 MYO1; myosin I
B Macropinocytosis
C Ras GTPases
C Kinases
D LDBPK_201140 phosphatidylinositol 3-kinase, putative K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]
D LDBPK_242090 phosphatidylinositol 3-kinase, putative K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]
C Phospholipase C
D LDBPK_302970 phospholipase C-like protein K05857 PLCD; phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]
D LDBPK_221530 phosphoinositide-specific phospholipase C, putative K05857 PLCD; phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]
C Sorting nexins
C Others
B Bin/Amphiphysin/Rvs (BAR) family proteins
C N-BAR proteins
C F-BAR proteins
C I-BAR proteins
B Rab GTPases and associated proteins
C Rab GTPases
C Rab associated proteins
D LDBPK_151210 inositol/phosphatidylinositol phosphatase, putative K01099 INPP5B_F; inositol polyphosphate 5-phosphatase INPP5B/F [EC:3.1.3.36]
D LDBPK_140020 phosphatidylinositol 3-kinase 2, putative K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
D LDBPK_201140 phosphatidylinositol 3-kinase, putative K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]
D LDBPK_242090 phosphatidylinositol 3-kinase, putative K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]
D LDBPK_281880 protein kinase, putative K08333 PIK3R4; phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1]
D LDBPK_362360 vacuolar protein sorting-associated protein 45-like protein K12479 VPS45; vacuolar protein sorting-associated protein 45
D LDBPK_221200 hypothetical protein K20027 ZDHHC1_11; palmitoyltransferase ZDHHC1/11 [EC:2.3.1.225]
B Arf GTPases and associated proteins
C Arf GTPases
D LDBPK_312350 ADP-ribosylation factor, putative K07937 ARF1_2; ADP-ribosylation factor 1/2
D LDBPK_040470 ADP-ribosylation factor, putative K07937 ARF1_2; ADP-ribosylation factor 1/2
D LDBPK_312890 ADP-ribosylation factor, putative K07937 ARF1_2; ADP-ribosylation factor 1/2
C Arf associated proteins
D LDBPK_321650 hypothetical protein K12486 SMAP; stromal membrane-associated protein
D LDBPK_261850 hypothetical protein K23538 ELMOD; ELMO domain-containing protein
B Others
C Fucosyltransferase
C EFR3-PI4KIII alpha complex and associated proteins
D LDBPK_291550 phosphatidylinositol-kinase domain protein, putative K00888 PI4KA; phosphatidylinositol 4-kinase A [EC:2.7.1.67]
D LDBPK_201540 hypothetical protein K21842 EFR3; protein EFR3
C Insulin-like growth factor-binding proteins
C Others
#
AEndosome - Lysosome transport
B Rab GTPases and associated proteins
C Rab GTPases
D LDBPK_180890 rab7 GTP binding protein, putative K07897 RAB7A; Ras-related protein Rab-7A
C Retromer subcomplex
D LDBPK_210530 vacuolar sorting-associated-like protein K18468 VPS35; vacuolar protein sorting-associated protein 35
D LDBPK_321110 vacuolar sorting-like protein K18467 VPS29; vacuolar protein sorting-associated protein 29
D LDBPK_363580 vacuolar protein sorting-associated protein-like protein K18466 VPS26A_B; vacuolar protein sorting-associated protein 26A/B
C FTS/Hook/FHIP (FHF) complex
C Rab associated proteins
D LDBPK_201140 phosphatidylinositol 3-kinase, putative K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]
D LDBPK_242090 phosphatidylinositol 3-kinase, putative K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]
D LDBPK_110240 proteasome alpha 7 subunit, putative K02731 PSMA7; 20S proteasome subunit alpha 4 [EC:3.4.25.1]
D LDBPK_171570 hypothetical protein K18469 TBC1D5; TBC1 domain family member 5
D LDBPK_343860 geranylgeranyltransferase, putative K05956 RABGGTB; geranylgeranyl transferase type-2 subunit beta [EC:2.5.1.60]
B Arf GTPases and associated proteins
C Arf GTPases
C BLOC-one-related complex (BORC)
C N-acetyl transferase complex C (NatC)
D LDBPK_171080 hypothetical protein K20823 NAA35; N-alpha-acetyltransferase 35, NatC auxiliary subunit
D LDBPK_161440 hypothetical protein K20824 NAA38; N-alpha-acetyltransferase 38, NatC auxiliary subunit
C Other Arf associated proteins
B Endosomal sorting complexes required for transport (ESCRT)
C ESCRT-0 complex
C ESCRT-I complex
D LDBPK_365400 vacuolar protein sorting-associated protein-like protein K12184 VPS28; ESCRT-I complex subunit VPS28
C ESCRT-II complex
D LDBPK_341570 hypothetical protein K12188 SNF8; ESCRT-II complex subunit VPS22
D LDBPK_360330 hypothetical protein K12189 VPS25; ESCRT-II complex subunit VPS25
D LDBPK_190740 hypothetical protein K12190 VPS36; ESCRT-II complex subunit VPS36
C ESCRT-III complex
D LDBPK_332010 vesicular protein trafficking mediator, putative K12197 CHMP1; charged multivesicular body protein 1
D LDBPK_354470 hypothetical protein K12197 CHMP1; charged multivesicular body protein 1
D LDBPK_271350 hypothetical protein K12191 CHMP2A; charged multivesicular body protein 2A
D LDBPK_363600 SNF7-like protein K12193 VPS24; charged multivesicular body protein 3
D LDBPK_364040 hypothetical protein K12194 CHMP4A_B; charged multivesicular body protein 4A/B
D LDBPK_350580 SNF-7-like protein, conserved K12198 CHMP5; charged multivesicular body protein 5
D LDBPK_160940 hypothetical protein K12195 CHMP6; charged multivesicular body protein 6
D LDBPK_292610 vacuolar protein sorting-associated protein 4 K12196 VPS4; vacuolar protein-sorting-associated protein 4
D LDBPK_343130 ATPase-like protein K12196 VPS4; vacuolar protein-sorting-associated protein 4
C ESCRT associated proteins
D LDBPK_050740 hypothetical protein K12199 VTA1; vacuolar protein sorting-associated protein VTA1
D LDBPK_271540 hypothetical protein K12200 PDCD6IP; programmed cell death 6-interacting protein
B Tethering complex
C CORVET complex
D LDBPK_365130 hypothetical protein K20178 VPS8; vacuolar protein sorting-associated protein 8
D LDBPK_312990 hypothetical protein K20179 VPS11; vacuolar protein sorting-associated protein 11
D LDBPK_181080 vacuolar protein sorting complex subunit, putative K20180 VPS16; vacuolar protein sorting-associated protein 16
D LDBPK_270770 hypothetical protein K20181 VPS18; vacuolar protein sorting-associated protein 18
D LDBPK_252280 vacuolar protein sorting-like protein K20182 VPS33A; vacuolar protein sorting-associated protein 33A
C Hops complex
D LDBPK_312990 hypothetical protein K20179 VPS11; vacuolar protein sorting-associated protein 11
D LDBPK_181080 vacuolar protein sorting complex subunit, putative K20180 VPS16; vacuolar protein sorting-associated protein 16
D LDBPK_270770 hypothetical protein K20181 VPS18; vacuolar protein sorting-associated protein 18
D LDBPK_252280 vacuolar protein sorting-like protein K20182 VPS33A; vacuolar protein sorting-associated protein 33A
D LDBPK_120910 hypothetical protein K20183 VPS39; Vam6/Vps39-like protein vacuolar protein sorting-associated protein 39
D LDBPK_301350 vacuolar assembly protein vps41, putative K20184 VPS41; vacuolar protein sorting-associated protein 41
B Acidification regulators
C Rabconnectin-3 complex
C RAVE complex
D LDBPK_111200 S-phase kinase-associated protein, putative K03094 SKP1; S-phase kinase-associated protein 1
B Others
C AP-3 complex
D LDBPK_080090 adaptor complex protein (AP) 3 delta subunit 1, putative K12396 AP3D; AP-3 complex subunit delta
D LDBPK_365490 adaptin, putative K12397 AP3B; AP-3 complex subunit beta
D LDBPK_342420 adaptor complex subunit medium chain 3, putative K12398 AP3M; AP-3 complex subunit mu
D LDBPK_241610 adaptor complex AP-3 small subunit, putative K12399 AP3S; AP-3 complex subunit sigma
C BLOC-1 complex
C BLOC-1 complex (yeast)
C BLOC-2 complex
C BLOC-3 complex
C Ferlins
C Others
D LDBPK_340310 hypothetical protein K20195 MON1; vacuolar fusion protein MON1
D LDBPK_210500 ubiquitin-conjugating enzyme-like protein K20656 TMEM189; plasmanylethanolamine desaturase [EC:1.14.19.77]
D LDBPK_343590 hypothetical protein K24260 WDR11; WD repeat-containing protein 11
#
AProtein recycling
B Rab GTPases and associated proteins
C Rab GTPases
D LDBPK_100960 small GTP-binding protein Rab11, putative K07904 RAB11A; Ras-related protein Rab-11A
D LDBPK_070610 ras-related protein rab-14, putative K07881 RAB14; Ras-related protein Rab-14
C Rab4 associated proteins
C Rab11 associated proteins
D LDBPK_320050 protein transport protein Sec13, putative K14004 SEC13; protein transport protein SEC13
D LDBPK_271920 hypothetical protein K23539 UNC119; protein unc-119
C Other Rab GTPase associated proteins
D LDBPK_151210 inositol/phosphatidylinositol phosphatase, putative K01099 INPP5B_F; inositol polyphosphate 5-phosphatase INPP5B/F [EC:3.1.3.36]
D LDBPK_280580 RAD51 protein, putative K04482 RAD51; DNA repair protein RAD51
B Others
C Glutamate receptor-interacting proteins (GRIPs)
C GRIP associated proteins
C EARP complex
D LDBPK_210390 hypothetical protein K20296 ANG2; vacuolar protein sorting-associated protein 51
D LDBPK_260340 hypothetical protein K20298 VPS52; vacuolar protein sorting-associated protein 52
D LDBPK_190810 hypothetical protein K20299 VPS53; vacuolar protein sorting-associated protein 53
D LDBPK_242260 hypothetical protein K23288 VPS50; syndetin
C WASH complex
D LDBPK_271560 hypothetical protein K18464 RTSC; WASH complex subunit strumpellin
D LDBPK_241320 hypothetical protein K18465 MRT43; WASH complex subunit 7
C Retriever complex
D LDBPK_321110 vacuolar sorting-like protein K18467 VPS29; vacuolar protein sorting-associated protein 29
C Others
D LDBPK_150260 hypothetical protein K23289 EIPR1; EARP and GARP complex-interacting protein 1
#
AEndosome - Golgi transport
B Rab GTPases and associated proteins
C Rab GTPases
C Rab associated proteins
D LDBPK_351740 dynein-associated roadblock protein-like protein K10419 DYNLRB; dynein light chain roadblock-type
D LDBPK_181010 dynein light chain 2B, cytoplasmic, putative K10419 DYNLRB; dynein light chain roadblock-type
D LDBPK_151210 inositol/phosphatidylinositol phosphatase, putative K01099 INPP5B_F; inositol polyphosphate 5-phosphatase INPP5B/F [EC:3.1.3.36]
D LDBPK_160780 hypothetical protein K19525 VPS13A_C; vacuolar protein sorting-associated protein 13A/C
B Arf GTPases and associated proteins
C Arf GTPases
D LDBPK_312350 ADP-ribosylation factor, putative K07937 ARF1_2; ADP-ribosylation factor 1/2
D LDBPK_040470 ADP-ribosylation factor, putative K07937 ARF1_2; ADP-ribosylation factor 1/2
D LDBPK_312890 ADP-ribosylation factor, putative K07937 ARF1_2; ADP-ribosylation factor 1/2
D LDBPK_170080 ADP-ribosylation factor, putative K07942 ARL1; ADP-ribosylation factor-like protein 1
C Arf GTPase associated proteins
D LDBPK_321290 ADP-ribosylation factor GTPase activating protein 1, putative K12492 ARFGAP1; ADP-ribosylation factor GTPase-activating protein 1
D LDBPK_130600 hypothetical protein K12493 ARFGAP2_3; ADP-ribosylation factor GTPase-activating protein 2/3
D LDBPK_321650 hypothetical protein K12486 SMAP; stromal membrane-associated protein
B Tethering complex
C Conserved oligomeric Golgi (COG) complex
D LDBPK_366300 hypothetical protein K20289 COG2; conserved oligomeric Golgi complex subunit 2
D LDBPK_361810 hypothetical protein K20290 COG3; conserved oligomeric Golgi complex subunit 3
D LDBPK_050600 hypothetical protein K20291 COG4; conserved oligomeric Golgi complex subunit 4
D LDBPK_323390 hypothetical protein K20292 COG5; conserved oligomeric Golgi complex subunit 5
D LDBPK_340390 hypothetical protein K20293 COG6; conserved oligomeric Golgi complex subunit 6
D LDBPK_283130 oligomeric golgi complex component 8, putative K20295 COG8; conserved oligomeric Golgi complex subunit 8
C GARP complex
D LDBPK_210390 hypothetical protein K20296 ANG2; vacuolar protein sorting-associated protein 51
D LDBPK_260340 hypothetical protein K20298 VPS52; vacuolar protein sorting-associated protein 52
D LDBPK_190810 hypothetical protein K20299 VPS53; vacuolar protein sorting-associated protein 53
D LDBPK_366470 hypothetical protein K17600 VPS54; vacuolar protein sorting-associated protein 54
C TRAPP complex II
D LDBPK_352930 hypothetical protein K20300 TRAPPC1; trafficking protein particle complex subunit 1
D LDBPK_161480 trafficking protein particle complex subunit-like protein K20302 TRAPPC3; trafficking protein particle complex subunit 3
D LDBPK_322860 hypothetical protein K20303 TRAPPC4; trafficking protein particle complex subunit 4
D LDBPK_353370 transport protein particle (TRAPP) subunit, putative K20280 TRAPPC5; trafficking protein particle complex subunit 5
D LDBPK_241360 hypothetical protein K20304 TRAPPC6; trafficking protein particle complex subunit 6
B Others
C AP-1 complex
D LDBPK_343800 adaptor gamma-1 chain, putative K12391 AP1G1; AP-1 complex subunit gamma-1
D LDBPK_367080 beta-adaptin, putative K12392 AP1B1; AP-1 complex subunit beta-1
D LDBPK_220960 adaptor complex AP-1 medium subunit, putative K12393 AP1M; AP-1 complex subunit mu
D LDBPK_291530 clathrin coat assembly protein ap19, putative K12394 AP1S1_2; AP-1 complex subunit sigma 1/2
C AP-3 complex
D LDBPK_080090 adaptor complex protein (AP) 3 delta subunit 1, putative K12396 AP3D; AP-3 complex subunit delta
D LDBPK_365490 adaptin, putative K12397 AP3B; AP-3 complex subunit beta
D LDBPK_342420 adaptor complex subunit medium chain 3, putative K12398 AP3M; AP-3 complex subunit mu
D LDBPK_241610 adaptor complex AP-3 small subunit, putative K12399 AP3S; AP-3 complex subunit sigma
C AP-4 complex
C GGA
C Aftiphilin/p200/gamma-synergin complex
C Others
D LDBPK_291550 phosphatidylinositol-kinase domain protein, putative K00888 PI4KA; phosphatidylinositol 4-kinase A [EC:2.7.1.67]
D LDBPK_044320 hypothetical protein K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
D LDBPK_291750 hypothetical protein K20318 SYS1; protein SYS1
D LDBPK_190310 hypothetical protein K23541 TMEM165; Ca2+/H+ antiporter, TMEM165/GDT1 family
D LDBPK_323610 hypothetical protein K26680 DOP1; protein dopey
D LDBPK_271810 hypothetical protein K26752 TVP23; golgi apparatus membrane protein TVP23
#
AEndoplasmic reticulum (ER) - Golgi transport
B Forward pathways
C Coat protein complex II (COP-II)
D LDBPK_050030 ras-like small GTPases, putative K07953 SAR1; GTP-binding protein SAR1 [EC:3.6.5.-]
D LDBPK_320050 protein transport protein Sec13, putative K14004 SEC13; protein transport protein SEC13
D LDBPK_111140 protein transport protein Sec31, putative K14005 SEC31; protein transport protein SEC31
D LDBPK_111150 protein transport protein Sec31, putative K14005 SEC31; protein transport protein SEC31
D LDBPK_366710 protein transport protein Sec23-like protein K14006 SEC23; protein transport protein SEC23
D LDBPK_251380 protein transport protein Sec24C, putative K14007 SEC24; protein transport protein SEC24
C TRAPP complex I
D LDBPK_352930 hypothetical protein K20300 TRAPPC1; trafficking protein particle complex subunit 1
D LDBPK_161480 trafficking protein particle complex subunit-like protein K20302 TRAPPC3; trafficking protein particle complex subunit 3
D LDBPK_322860 hypothetical protein K20303 TRAPPC4; trafficking protein particle complex subunit 4
D LDBPK_353370 transport protein particle (TRAPP) subunit, putative K20280 TRAPPC5; trafficking protein particle complex subunit 5
D LDBPK_241360 hypothetical protein K20304 TRAPPC6; trafficking protein particle complex subunit 6
C p24 family proteins
D LDBPK_322150 cop-coated vesicle membrane protein p24 precursor, putative K20347 TMED2; p24 family protein beta-1
D LDBPK_311120 hypothetical protein K20347 TMED2; p24 family protein beta-1
D LDBPK_351840 COP-coated vesicle membrane protein gp25L precursor, putative K20352 TMED10; p24 family protein delta-1
C PDI family proteins
D LDBPK_260630 protein disulfide isomerase, putative K09584 PDIA6; protein disulfide-isomerase A6 [EC:5.3.4.1]
D LDBPK_341960 hypothetical protein K09584 PDIA6; protein disulfide-isomerase A6 [EC:5.3.4.1]
C Rab GTPases
D LDBPK_270620 small GTP-binding protein Rab1, putative K07874 RAB1A; Ras-related protein Rab-1A
D LDBPK_322160 ras-related protein rab-2a, putative K07877 RAB2A; Ras-related protein Rab-2A
C Rab associated proteins
D LDBPK_331600 hypothetical protein K20359 RABAC1; PRA1 family protein 1
D LDBPK_201600 hypothetical protein K20372 TBC1D20; TBC1 domain family member 20
D LDBPK_301410 GTPase activating protein, putative K20360 TBC1D22; TBC1 domain family member 2
D LDBPK_201160 hypothetical protein K20362 YIF1; protein transport protein YIF1
D LDBPK_352550 hypothetical protein K22939 IER3IP1; immediate early response 3-interacting protein 1
C ER-Golgi intermediate compartment (ERGIC) proteins
D LDBPK_130560 lectin, putative K10080 LMAN1; lectin, mannose-binding 1
D LDBPK_324060 hypothetical protein, unknown function K20365 ERGIC1; endoplasmic reticulum-Golgi intermediate compartment protein 1
D LDBPK_312830 hypothetical protein K20367 ERGIC3; endoplasmic reticulum-Golgi intermediate compartment protein 3
D LDBPK_323990 hypothetical protein K20368 CNIH; protein cornichon
D LDBPK_323980 hypothetical protein K20368 CNIH; protein cornichon
D LDBPK_281310 glucose-regulated protein 78, putative K09490 HSPA5; endoplasmic reticulum chaperone BiP [EC:3.6.4.10]
B Retrieval pathways
C Coat protein complex I (COP-I)
D LDBPK_344140 coatomer alpha subunit, putative K05236 COPA; coatomer subunit alpha
D LDBPK_201390 coatomer beta subunit, putative K17301 COPB1; coatomer subunit beta
D LDBPK_333360 beta prime cop protein, putative K17302 COPB2; coatomer subunit beta'
D LDBPK_282820 coatomer gamma subunit, putative K17267 COPG; coatomer subunit gamma
D LDBPK_161230 coatomer delta subunit-like protein K20471 COPD; coatomer subunit delta
D LDBPK_321810 coatomer epsilon subunit, putative K17268 COPE; coatomer subunit epsilon
D LDBPK_350110 coatomer zeta subunit, putative K20472 COPZ; coatomer subunit zeta
C NRZ (DSL1) complex
C Golgi to ER traffic proteins (GET)
D LDBPK_110710 anion-transporting ATPase-like protein K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-]
C Rab GTPases
C Rab associated proteins
D LDBPK_320810 hypothetical protein K20476 RIC1; RAB6A-GEF complex partner protein 1
D LDBPK_280670 ER lumen retaining receptor-like protein K10949 KDELR; ER lumen protein retaining receptor
D LDBPK_301410 GTPase activating protein, putative K20360 TBC1D22; TBC1 domain family member 2
B Others
C Oxysterol-binding proteins
C FXYD proteins
C YIPF proteins
D LDBPK_300140 hypothetical protein K22940 YIPF1_2; protein YIPF1/2
D LDBPK_262210 hypothetical protein K20363 YIPF5_7; protein YIPF5/7
D LDBPK_230280 terbinafine resistance locus protein (yip1) K22943 YIPF6; protein YIPF6
C ER membrane protein complex
D LDBPK_170230 hypothetical protein K23563 EMC2; ER membrane protein complex subunit 2
D LDBPK_360390 hypothetical protein K23564 EMC3; ER membrane protein complex subunit 3
D LDBPK_301660 hypothetical protein K23565 EMC4; ER membrane protein complex subunit 4
D LDBPK_342090 hypothetical protein K23566 MMGT1; membrane magnesium transporter 1
D LDBPK_323170 hypothetical protein K23567 EMC6; ER membrane protein complex subunit 6
D LDBPK_260650 hypothetical protein K23568 EMC7; ER membrane protein complex subunit 7
D LDBPK_070450 hypothetical protein K23569 EMC8_9; ER membrane protein complex subunit 8/9
C SEC61 complex
D LDBPK_111050 pretranslocation protein, alpha subunit, putative K10956 SEC61A; protein transport protein SEC61 subunit alpha
D LDBPK_251050 protein transport protein Sec61 gamma subunit, putative K07342 SEC61G; protein transport protein SEC61 subunit gamma and related proteins
C TRAP complex
D LDBPK_220130 hypothetical protein K13249 SSR1; translocon-associated protein subunit alpha
C Multi-pass translocon (MPT) complex
D LDBPK_261020 hypothetical protein K26499 NCLN; BOS complex subunit NCLN
C Post-GPI attachment to proteins factors (PGAP)
C Others
D LDBPK_262380 sec1 family transport protein, putative K19998 SCFD1; sec1 family domain-containing protein 1
D LDBPK_252510 hypothetical protein K21848 ARV1; lipid intermediate transporter
D LDBPK_341380 hypothetical protein K22128 PIEZO1_2; piezo-type mechanosensitive ion channel component 1/2
D LDBPK_320380 hypothetical protein K22698 SEY1; protein SEY1 [EC:3.6.5.-]
#
AAutophagy
B Autophagosome formation proteins
C ULK complex
C Atg1 complex
C PI3K complex
D LDBPK_201140 phosphatidylinositol 3-kinase, putative K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]
D LDBPK_242090 phosphatidylinositol 3-kinase, putative K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]
D LDBPK_281880 protein kinase, putative K08333 PIK3R4; phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1]
C ATG9 transmembrane protein
D LDBPK_270400 hypothetical protein K17907 ATG9; autophagy-related protein 9
C Atg18-Atg2 complex
C Atg12 conjugation proteins
D LDBPK_070010 ubiquitin activating E1 enzyme, putative K08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7
C Atg8 conjugation proteins
D LDBPK_191660 ATG8/AUT7/APG8/PAZ2, putative K08341 GABARAP; GABA(A) receptor-associated protein
D LDBPK_190840 ATG8/AUT7/APG8/PAZ2, putative K08341 GABARAP; GABA(A) receptor-associated protein
D LDBPK_324040 AUT2/APG4/ATG4 cysteine peptidase, putative K08342 ATG4; cysteine protease ATG4 [EC:3.4.22.-]
D LDBPK_070010 ubiquitin activating E1 enzyme, putative K08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7
D LDBPK_330320 autophagocytosis protein, putative K08343 ATG3; ubiquitin-like-conjugating enzyme ATG3
B Cytoplasm to vacuolar targeting (CVT) pathway
C Selective cargos
D LDBPK_292470 aspartyl aminopeptidase, putative K01267 DNPEP; aspartyl aminopeptidase [EC:3.4.11.21]
C Cargo receptors
C Scaffold protein
C Other Cvt associated proteins
B Mitophagy
C Cargo receptors
C Scaffold proteins
C PINK1-Parkin associated proteins
C Other mitophagy associated proteins
D LDBPK_210300 hexokinase, putative K00844 HK; hexokinase [EC:2.7.1.1]
B Pexophagy
C Selective cargos
D LDBPK_212210 peroxin 14, putative K13343 PEX14; peroxin-14
C Cargo receptors
C Other pexophagy associated proteins
B Aggrephagy
C Cargo receptors
C Scaffold proteins
C Other aggrephagy associated proteins
D LDBPK_361420 Transitional endoplasmic reticulum ATPase, putative K13525 VCP; transitional endoplasmic reticulum ATPase
B Xenophagy
C Cargo receptors
C Other xenophagy associated proteins
B Chaperone mediated autophagy (CMA)
C Selective cargos
D LDBPK_361320 fructose-1,6-bisphosphate aldolase K01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D LDBPK_350840 aspartate aminotransferase, putative K14454 GOT1; aspartate aminotransferase, cytoplasmic [EC:2.6.1.1]
D LDBPK_354810 glyceraldehyde-3-phosphate dehydrogenase-like protein K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D LDBPK_303000 glyceraldehyde 3-phosphate dehydrogenase, glycosomal K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D LDBPK_302990 glyceraldehyde 3-phosphate dehydrogenase, glycosomal K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D LDBPK_362480 glyceraldehyde 3-phosphate dehydrogenase, cytosolic K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D LDBPK_055450 hypothetical protein K00873 PK; pyruvate kinase [EC:2.7.1.40]
D LDBPK_360590 ubiquitin-like protein, putative K04523 UBQLN; ubiquilin
C Cargo receptors
C Chaperones
D LDBPK_283000 heat-shock protein hsp70, putative K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D LDBPK_283040 heat shock protein 70, putative K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D LDBPK_261220 heat shock protein 70-related protein K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D LDBPK_330360 heat shock protein 83-1 K04079 HSP90A; molecular chaperone HtpG
D LDBPK_330370 heat shock protein 83-1 K04079 HSP90A; molecular chaperone HtpG
D LDBPK_330350 heat shock protein 83-1 K04079 HSP90A; molecular chaperone HtpG
C Co-chaperones
D LDBPK_290330 hypothetical protein K09560 ST13; suppressor of tumorigenicity protein 13
C Other CMA associated proteins
D LDBPK_170170 elongation factor 1-alpha K03231 EEF1A; elongation factor 1-alpha
D LDBPK_180450 serine carboxypeptidase (CBP1), putative K13289 CTSA; cathepsin A (carboxypeptidase C) [EC:3.4.16.5]
B Other autophagy associated proteins
C RNautophagy/DNautophagy
C Micronucleophagy
C Midbophagy
C Glycophagy
C TRIM-directed selective autophagy
C ER-mitochondria tethering complex
C mTORC1 complex
D LDBPK_366580 phosphatidylinositol 3 kinase, putative K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
D LDBPK_343750 phosphatidylinositol 3-kinase-like protein K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
D LDBPK_344160 phosphatidylinositol 3-kinase (tor2)-like protein K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
D LDBPK_250620 hypothetical protein K07204 RAPTOR; regulatory associated protein of mTOR
C mTORC2 complex
D LDBPK_366580 phosphatidylinositol 3 kinase, putative K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
D LDBPK_343750 phosphatidylinositol 3-kinase-like protein K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
D LDBPK_344160 phosphatidylinositol 3-kinase (tor2)-like protein K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
D LDBPK_231500 hypothetical protein K08267 RICTOR; rapamycin-insensitive companion of mTOR
C SEACIT/GATOR1 complex
C SEACAT/GATOR2 complex
D LDBPK_320050 protein transport protein Sec13, putative K14004 SEC13; protein transport protein SEC13
C KICSTOR complex
C Rab GTPases
D LDBPK_270620 small GTP-binding protein Rab1, putative K07874 RAB1A; Ras-related protein Rab-1A
C Rab associated proteins
C Others
D LDBPK_292140 serine/threonine protein kinase, putative K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
D LDBPK_251360 serine/threonine protein phosphatase, putative K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
D LDBPK_303510 hypothetical protein K24928 TTC5; tetratricopeptide repeat protein 5
#
AOthers
B NADPH oxidases (Nox) and associated proteins
C NADPH oxidases
C Nox associated proteins
B Actin-binding proteins
C Myosins
D LDBPK_341070 myosin IB heavy chain, putative K10356 MYO1; myosin I
C Arp2/3 complex
D LDBPK_020570 ARP2/3 complex subunit, putative K05755 ARPC4; actin related protein 2/3 complex, subunit 4
D LDBPK_191190 actin-related protein 2, putative K17260 ACTR2; actin-related protein 2
D LDBPK_151410 actin-related protein 3, putative arp3 K18584 ACTR3; actin-related protein 3
C Nucleation-promoting factors (NPFs)
C Others
D LDBPK_320550 profilin, putative K05759 PFN; profilin
D LDBPK_290520 cofilin-like protein K05765 CFL; cofilin
B Mucins
C Membrane bound mucins
C Secretory mucins
B Rab GTPases of specific organelles
C Melanosome
C Auto phagosome
C Lipid droplets
C Mitochondrion
B Rho GTPase associated proteins
C Rho GTPase-activating proteins
C Rho guanine nucleotide exchange factors (GEFs)
!
#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: April 10, 2024