+D Receptor KO
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G Protein-Coupled Receptors - Lottia gigantea (owl limpet)
%
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ARhodopsin family
B Biogenic amine
C Acetylcholine (muscarinic)
D LOTGIDRAFT_134322 hypothetical protein K04131 CHRM3; muscarinic acetylcholine receptor M3
D LOTGIDRAFT_132084 hypothetical protein K04131 CHRM3; muscarinic acetylcholine receptor M3
D LOTGIDRAFT_152120 hypothetical protein K04134 CHRMN; muscarinic acetylcholine receptor
D LOTGIDRAFT_111898 hypothetical protein K04134 CHRMN; muscarinic acetylcholine receptor
D LOTGIDRAFT_157546 hypothetical protein K04134 CHRMN; muscarinic acetylcholine receptor
D LOTGIDRAFT_157548 hypothetical protein K04134 CHRMN; muscarinic acetylcholine receptor
D LOTGIDRAFT_157549 hypothetical protein K04134 CHRMN; muscarinic acetylcholine receptor
D LOTGIDRAFT_159014 hypothetical protein K04134 CHRMN; muscarinic acetylcholine receptor
D LOTGIDRAFT_158431 hypothetical protein K04134 CHRMN; muscarinic acetylcholine receptor
D LOTGIDRAFT_131653 hypothetical protein K04134 CHRMN; muscarinic acetylcholine receptor
C Adrenaline
D LOTGIDRAFT_142302 hypothetical protein K04137 ADRA1D; adrenergic receptor alpha-1D
D LOTGIDRAFT_183801 hypothetical protein K04142 ADRB2; adrenergic receptor beta-2
C Dopamine
D LOTGIDRAFT_161905 hypothetical protein K04144 DRD1; dopamine receptor D1
D LOTGIDRAFT_94741 hypothetical protein K04144 DRD1; dopamine receptor D1
D LOTGIDRAFT_162560 hypothetical protein K04144 DRD1; dopamine receptor D1
D LOTGIDRAFT_229072 hypothetical protein K04145 DRD2; dopamine receptor D2
D LOTGIDRAFT_166315 hypothetical protein K04145 DRD2; dopamine receptor D2
D LOTGIDRAFT_209429 hypothetical protein K04145 DRD2; dopamine receptor D2
D LOTGIDRAFT_168534 hypothetical protein K04145 DRD2; dopamine receptor D2
D LOTGIDRAFT_144771 hypothetical protein K04148 DRD1N; dopamine receptor D1-like
C Dopamine and ecdysteroid
D LOTGIDRAFT_95891 hypothetical protein K22919 DopEcR; dopamine/ecdysteroid receptor
C Histamine
D LOTGIDRAFT_91892 hypothetical protein K04149 HRH1; histamine receptor H1
D LOTGIDRAFT_84168 hypothetical protein K04150 HRH2; histamine receptor H2
D LOTGIDRAFT_158544 hypothetical protein K04150 HRH2; histamine receptor H2
D LOTGIDRAFT_84413 hypothetical protein K04150 HRH2; histamine receptor H2
D LOTGIDRAFT_132263 hypothetical protein K04150 HRH2; histamine receptor H2
D LOTGIDRAFT_190505 hypothetical protein K04151 HRH3; histamine receptor H3
C Octopamine and tryamine
D LOTGIDRAFT_178787 hypothetical protein K04165 Oamb; octopamine receptor
D LOTGIDRAFT_64845 hypothetical protein K22814 Octalpha; octopamine receptor alpha
D LOTGIDRAFT_178224 hypothetical protein K22790 Octbeta; octopamine receptor beta
D LOTGIDRAFT_130962 hypothetical protein K22815 Oct-TyrR; octopamine/tyramine receptor
C Serotonin
D LOTGIDRAFT_134511 hypothetical protein K04153 HTR1; 5-hydroxytryptamine receptor 1
D LOTGIDRAFT_82265 hypothetical protein K04157 HTR2; 5-hydroxytryptamine receptor 2
D LOTGIDRAFT_155726 hypothetical protein K04160 HTR4; 5-hydroxytryptamine receptor 4
D LOTGIDRAFT_108926 hypothetical protein K04163 HTR7; 5-hydroxytryptamine receptor 7
C Trace amine
B Peptide
C Adrenomedullin (G10D)
C Adropin
D LOTGIDRAFT_208014 hypothetical protein K04316 GPR19; G protein-coupled receptor 19
C Apelin
C Anaphylatoxin
C Angiotensin
C BigLEN
C Bombesin
D LOTGIDRAFT_95484 hypothetical protein K04170 BRS3; bombesin receptor subtype-3
D LOTGIDRAFT_108343 hypothetical protein K04170 BRS3; bombesin receptor subtype-3
C Bradykinin
C Cholecystokinin
D LOTGIDRAFT_152277 hypothetical protein K04194 CCKAR; cholecystokinin A receptor
D LOTGIDRAFT_158556 hypothetical protein K04194 CCKAR; cholecystokinin A receptor
D LOTGIDRAFT_239028 hypothetical protein K04194 CCKAR; cholecystokinin A receptor
D LOTGIDRAFT_158646 hypothetical protein K04194 CCKAR; cholecystokinin A receptor
D LOTGIDRAFT_236803 hypothetical protein K04194 CCKAR; cholecystokinin A receptor
D LOTGIDRAFT_171870 hypothetical protein K04194 CCKAR; cholecystokinin A receptor
D LOTGIDRAFT_111574 hypothetical protein K04194 CCKAR; cholecystokinin A receptor
D LOTGIDRAFT_111302 hypothetical protein K04194 CCKAR; cholecystokinin A receptor
D LOTGIDRAFT_171752 hypothetical protein K04194 CCKAR; cholecystokinin A receptor
D LOTGIDRAFT_153681 hypothetical protein K04194 CCKAR; cholecystokinin A receptor
D LOTGIDRAFT_153686 hypothetical protein K04194 CCKAR; cholecystokinin A receptor
D LOTGIDRAFT_125270 hypothetical protein K04194 CCKAR; cholecystokinin A receptor
D LOTGIDRAFT_155829 hypothetical protein K04194 CCKAR; cholecystokinin A receptor
C Endothelin
C fMet-Leu-Phe
C Follicle stimulating hormone (FSH)
C Galanin
D LOTGIDRAFT_91997 hypothetical protein K04230 GALR1; galanin receptor 1
D LOTGIDRAFT_108200 hypothetical protein K04233 ASTA-R; allatostatin A receptor
D LOTGIDRAFT_228058 hypothetical protein K04233 ASTA-R; allatostatin A receptor
C Ghrelin
D LOTGIDRAFT_135960 hypothetical protein K04284 GHSR; growth hormone secretagogue receptor
C Gonadotropin-releasing hormone (GnRH)
D LOTGIDRAFT_103088 hypothetical protein K04280 GNRHR; gonadotropin-releasing hormone receptor
D LOTGIDRAFT_173242 hypothetical protein K04280 GNRHR; gonadotropin-releasing hormone receptor
D LOTGIDRAFT_140886 hypothetical protein K04280 GNRHR; gonadotropin-releasing hormone receptor
C Lutropin-choriogonadotropic hormone
C Melanin-concentrating hormone (MCH)
C Melanocortin
C Motilin
C Neuromedin U
D LOTGIDRAFT_159754 hypothetical protein K05052 NMUR1; neuromedin U receptor 1
D LOTGIDRAFT_144597 hypothetical protein K05052 NMUR1; neuromedin U receptor 1
D LOTGIDRAFT_95525 hypothetical protein K05052 NMUR1; neuromedin U receptor 1
D LOTGIDRAFT_93568 hypothetical protein K05052 NMUR1; neuromedin U receptor 1
D LOTGIDRAFT_169131 hypothetical protein K05052 NMUR1; neuromedin U receptor 1
D LOTGIDRAFT_161360 hypothetical protein K05052 NMUR1; neuromedin U receptor 1
D LOTGIDRAFT_91538 hypothetical protein K05052 NMUR1; neuromedin U receptor 1
D LOTGIDRAFT_156959 hypothetical protein K05053 NMUR2; neuromedin U receptor 2
D LOTGIDRAFT_159415 hypothetical protein K05053 NMUR2; neuromedin U receptor 2
D LOTGIDRAFT_161976 hypothetical protein K05053 NMUR2; neuromedin U receptor 2
C Neuropeptide FF
D LOTGIDRAFT_71923 hypothetical protein K08375 NPFFR2; neuropeptide FF receptor 2
D LOTGIDRAFT_108319 hypothetical protein K08375 NPFFR2; neuropeptide FF receptor 2
D LOTGIDRAFT_167044 hypothetical protein K08375 NPFFR2; neuropeptide FF receptor 2
D LOTGIDRAFT_106319 hypothetical protein K08375 NPFFR2; neuropeptide FF receptor 2
C Neuropeptide S
D LOTGIDRAFT_226790 hypothetical protein K08376 NPSR1; neuropeptide S receptor
D LOTGIDRAFT_126859 hypothetical protein K08376 NPSR1; neuropeptide S receptor
D LOTGIDRAFT_139356 hypothetical protein K08376 NPSR1; neuropeptide S receptor
D LOTGIDRAFT_94997 hypothetical protein K08376 NPSR1; neuropeptide S receptor
D LOTGIDRAFT_65275 hypothetical protein K08376 NPSR1; neuropeptide S receptor
C Neuropeptide W / neuropeptide B
C Neuropeptide Y
D LOTGIDRAFT_65232 hypothetical protein K04210 GPR83; G protein-coupled receptor 83
D LOTGIDRAFT_55047 hypothetical protein K04210 GPR83; G protein-coupled receptor 83
D LOTGIDRAFT_115283 hypothetical protein K04209 NPFR; neuropeptide F receptor
D LOTGIDRAFT_108855 hypothetical protein K04209 NPFR; neuropeptide F receptor
D LOTGIDRAFT_127250 hypothetical protein K04209 NPFR; neuropeptide F receptor
D LOTGIDRAFT_73358 hypothetical protein K04209 NPFR; neuropeptide F receptor
C Neurotensin
C Opioid
D LOTGIDRAFT_157036 hypothetical protein K04216 OPRL1; nociceptin receptor
D LOTGIDRAFT_159904 hypothetical protein K04216 OPRL1; nociceptin receptor
D LOTGIDRAFT_110771 hypothetical protein K04216 OPRL1; nociceptin receptor
C Orexigenic neuropeptide QRFP
D LOTGIDRAFT_157550 hypothetical protein K08378 QRFPR; pyroglutamylated RFamide peptide receptor
D LOTGIDRAFT_144441 hypothetical protein K08378 QRFPR; pyroglutamylated RFamide peptide receptor
C Orexin
D LOTGIDRAFT_166703 hypothetical protein K04238 HCRTR1; hypocretin (orexin) receptor 1
D LOTGIDRAFT_152502 hypothetical protein K04239 HCRTR2; hypocretin (orexin) receptor 2
D LOTGIDRAFT_162500 hypothetical protein K04239 HCRTR2; hypocretin (orexin) receptor 2
D LOTGIDRAFT_162749 hypothetical protein K04239 HCRTR2; hypocretin (orexin) receptor 2
D LOTGIDRAFT_120990 hypothetical protein K04239 HCRTR2; hypocretin (orexin) receptor 2
D LOTGIDRAFT_171849 hypothetical protein K04239 HCRTR2; hypocretin (orexin) receptor 2
D LOTGIDRAFT_156802 hypothetical protein K04239 HCRTR2; hypocretin (orexin) receptor 2
D LOTGIDRAFT_162575 hypothetical protein K04239 HCRTR2; hypocretin (orexin) receptor 2
D LOTGIDRAFT_126576 hypothetical protein K04239 HCRTR2; hypocretin (orexin) receptor 2
D LOTGIDRAFT_127723 hypothetical protein K04239 HCRTR2; hypocretin (orexin) receptor 2
D LOTGIDRAFT_171228 hypothetical protein K04239 HCRTR2; hypocretin (orexin) receptor 2
D LOTGIDRAFT_52425 hypothetical protein K04239 HCRTR2; hypocretin (orexin) receptor 2
D LOTGIDRAFT_231336 hypothetical protein K04239 HCRTR2; hypocretin (orexin) receptor 2
C Oxytocin
C Prokineticin
D LOTGIDRAFT_156580 hypothetical protein K08380 PROKR2; prokineticin receptor 2
C Prolactin-releasing peptide (PrRP)
C Prosaposin
C Relaxin
C Somatostatin
D LOTGIDRAFT_152311 hypothetical protein K04219 SSTR3; somatostatin receptor 3
D LOTGIDRAFT_108441 hypothetical protein K22872 ASTC-R; allatostatin C receptor
C Tachykinin
D LOTGIDRAFT_166607 hypothetical protein K04223 TACR2; tachykinin receptor 2
D LOTGIDRAFT_152934 hypothetical protein K04223 TACR2; tachykinin receptor 2
D LOTGIDRAFT_182876 hypothetical protein K04224 TACR3; tachykinin receptor 3
D LOTGIDRAFT_107384 hypothetical protein K04224 TACR3; tachykinin receptor 3
D LOTGIDRAFT_117895 hypothetical protein K14071 LKR; leucokinin receptor
D LOTGIDRAFT_93159 hypothetical protein K14072 Rya-R; RYamide receptor
D LOTGIDRAFT_105957 hypothetical protein K14072 Rya-R; RYamide receptor
D LOTGIDRAFT_53969 hypothetical protein K14072 Rya-R; RYamide receptor
D LOTGIDRAFT_127919 hypothetical protein K14072 Rya-R; RYamide receptor
D LOTGIDRAFT_72476 hypothetical protein K14072 Rya-R; RYamide receptor
C Thrombin
C Thyrotropin
D LOTGIDRAFT_92538 hypothetical protein K04249 TSHR; thyrotropin receptor
C Thyrotropin-releasing hormone (TRH)
D LOTGIDRAFT_165255 hypothetical protein K04282 TRHR; thyrotropin-releasing hormone receptor
D LOTGIDRAFT_122499 hypothetical protein K04282 TRHR; thyrotropin-releasing hormone receptor
D LOTGIDRAFT_153971 hypothetical protein K04282 TRHR; thyrotropin-releasing hormone receptor
C Urotensin II
C Vasopressin
D LOTGIDRAFT_140457 hypothetical protein K04226 AVPR1A; arginine vasopressin receptor 1A
D LOTGIDRAFT_52339 hypothetical protein K04226 AVPR1A; arginine vasopressin receptor 1A
C Neuropeptide receptors
D LOTGIDRAFT_94766 hypothetical protein K26200 SPR; sex peptide receptor
D LOTGIDRAFT_153588 hypothetical protein K26201 FMRFaR; FMRFamide receptor
D LOTGIDRAFT_94907 hypothetical protein K26201 FMRFaR; FMRFamide receptor
D LOTGIDRAFT_66365 hypothetical protein K26201 FMRFaR; FMRFamide receptor
D LOTGIDRAFT_172301 hypothetical protein K26202 Proc-R; proctolin receptor
D LOTGIDRAFT_159536 hypothetical protein K26202 Proc-R; proctolin receptor
D LOTGIDRAFT_105773 hypothetical protein K26203 MsR; myosuppressin receptor
D LOTGIDRAFT_95120 hypothetical protein K26203 MsR; myosuppressin receptor
D LOTGIDRAFT_160192 hypothetical protein K26203 MsR; myosuppressin receptor
D LOTGIDRAFT_114444 hypothetical protein K26203 MsR; myosuppressin receptor
B Chemokine
C CC Chemokine
D LOTGIDRAFT_238221 hypothetical protein K08417 GPR75; G protein-coupled receptor 75
C CXC Chemokine
C CX3C Chemokine
C C Chemokine
C Chemokine like
B Base and nucleoside
C Purine / pyrimidine
C Adenosine
B Lipid
C Arachidonylglycine
C Bile acid
C Cysteinyl leukotriene
C Free fatty acid
D LOTGIDRAFT_127041 hypothetical protein K08425 FFAR4; free fatty acid receptor 4
C HETE and oxoETE
C Leukotriene
C Lysophosphatidic acid
C Lysophosphatidylinositol
C Lysophosphatidylserine
C Oleoylethanolamide
C Prostaglandin
D LOTGIDRAFT_73186 hypothetical protein K04261 PTGER4; prostaglandin E receptor 4
D LOTGIDRAFT_73649 hypothetical protein K04261 PTGER4; prostaglandin E receptor 4
D LOTGIDRAFT_128640 hypothetical protein K04261 PTGER4; prostaglandin E receptor 4
D LOTGIDRAFT_194810 hypothetical protein K04261 PTGER4; prostaglandin E receptor 4
C Prostacyclin
C Sphingolipid
C Thromboxane
B Vision
C Opsin
D LOTGIDRAFT_64356 hypothetical protein K04256 OPN3; c-opsin
D LOTGIDRAFT_72363 hypothetical protein K04256 OPN3; c-opsin
D LOTGIDRAFT_156440 hypothetical protein K04255 OPN4; r-opsin
D LOTGIDRAFT_108602 hypothetical protein K04255 OPN4; r-opsin
D LOTGIDRAFT_154846 hypothetical protein K04255 OPN4; r-opsin
D LOTGIDRAFT_173452 hypothetical protein K04255 OPN4; r-opsin
D LOTGIDRAFT_140119 hypothetical protein K08385 OPN5; G0-opsin
D LOTGIDRAFT_152675 hypothetical protein K04253 RRH; visual pigment-like receptor peropsin
D LOTGIDRAFT_155231 hypothetical protein K04253 RRH; visual pigment-like receptor peropsin
D LOTGIDRAFT_122769 hypothetical protein K04253 RRH; visual pigment-like receptor peropsin
D LOTGIDRAFT_154374 hypothetical protein K04253 RRH; visual pigment-like receptor peropsin
D LOTGIDRAFT_116468 hypothetical protein K04253 RRH; visual pigment-like receptor peropsin
B Others
C Alpha-ketoglutarate
C Cannabinoid
D LOTGIDRAFT_116779 hypothetical protein K04277 CNR1; cannabinoid receptor 1
C Estrogen
C Hydroxy-carboxylic acid
C L-Tryptophan and L-Phenylalanine
D LOTGIDRAFT_84528 hypothetical protein K08428 GPR139; G protein-coupled receptor 139
D LOTGIDRAFT_159064 hypothetical protein K08428 GPR139; G protein-coupled receptor 139
C Mas proto-oncogene and Mas-related (MRGs)
C Melatonin
C Oxysterol
C Platelet activating factor
C Proton-sensing GPCRs
C R-spondin
D LOTGIDRAFT_115178 hypothetical protein K08399 LGR6; leucine-rich repeat-containing G protein-coupled receptor 6
C Super conserved receptor expressed in brain (SREB)
D LOTGIDRAFT_105214 hypothetical protein K04302 SREB2; super conserved receptor expressed in brain 2
C Trissin
D LOTGIDRAFT_103326 hypothetical protein K22792 TrissinR; trissin receptor
C Orphan GPCRs / unclassified GPCRs
D LOTGIDRAFT_154412 hypothetical protein K04319 GPR22; G protein-coupled receptor 22
D LOTGIDRAFT_105958 hypothetical protein K08409 GPR45; G protein-coupled receptor 45
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ASecretin receptor family
B Calcium-regulating peptide
C Calcitonin
D LOTGIDRAFT_109332 hypothetical protein K04576 CALCR; calcitonin receptor
D LOTGIDRAFT_170937 hypothetical protein K04576 CALCR; calcitonin receptor
D LOTGIDRAFT_234777 hypothetical protein K04576 CALCR; calcitonin receptor
D LOTGIDRAFT_172709 hypothetical protein K04576 CALCR; calcitonin receptor
C Parathyroid hormone
D LOTGIDRAFT_238709 hypothetical protein K04585 PTH1R; parathyroid hormone receptor 1
D LOTGIDRAFT_62404 hypothetical protein K04585 PTH1R; parathyroid hormone receptor 1
D LOTGIDRAFT_132034 hypothetical protein K04585 PTH1R; parathyroid hormone receptor 1
D LOTGIDRAFT_129435 hypothetical protein K04585 PTH1R; parathyroid hormone receptor 1
B Hypothalamic hormone
C Corticotropin-releasing hormone (CRH)
D LOTGIDRAFT_141716 hypothetical protein K04579 CRHR2; corticotropin releasing hormone receptor 2
C Growth hormone-releasing hormone (GHRH)
B Pancreatic peptide
C Glucagon
B Gut peptide
C Gastric inhibitory peptide (GIP)
C Vasoactive intestinal polypeptide (VIP) and pituitary adenyl cyclase-activating peptide (PACAP)
C Secretin
D LOTGIDRAFT_53326 hypothetical protein K04588 SCTR; secretin receptor
D LOTGIDRAFT_141719 hypothetical protein K04588 SCTR; secretin receptor
B Others
C Receptor activity modifying protein
C Methuselah-like proteins (MTH)
D LOTGIDRAFT_108512 hypothetical protein K04599 MTH; G protein-coupled receptor Mth (Methuselah protein)
C Pigment dispersing factor (PDF)
D LOTGIDRAFT_134519 hypothetical protein K22738 PDFR; PDF receptor
D LOTGIDRAFT_173381 hypothetical protein K22738 PDFR; PDF receptor
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AAdhesion receptor family
B Cadherin EGF LAG (CELSR)
B EGF-like module-containing mucin-like hormone receptor-like (EMR)
B Latrophilin
B Brain-specific angiogenesis inhibitor (BAI)
B Others
C LOTGIDRAFT_140702 hypothetical protein K08462 ADGRA3; adhesion G protein-coupled receptor A3
C LOTGIDRAFT_154761 hypothetical protein K08465 ADGRD1; adhesion G-protein coupled receptor D1
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AMetabotropic glutamate receptor family
B Glutamate (metabotropic)
C LOTGIDRAFT_130830 hypothetical protein K04606 GRM3; metabotropic glutamate receptor 3
C LOTGIDRAFT_108603 hypothetical protein K04606 GRM3; metabotropic glutamate receptor 3
B GABA
C LOTGIDRAFT_160603 hypothetical protein K04615 GABBR; gamma-aminobutyric acid type B receptor
C LOTGIDRAFT_133032 hypothetical protein K04615 GABBR; gamma-aminobutyric acid type B receptor
C LOTGIDRAFT_141127 hypothetical protein K04615 GABBR; gamma-aminobutyric acid type B receptor
C LOTGIDRAFT_122938 hypothetical protein K04615 GABBR; gamma-aminobutyric acid type B receptor
C LOTGIDRAFT_165568 hypothetical protein K04615 GABBR; gamma-aminobutyric acid type B receptor
B Calcium-sensing
B Orphan GPRC5
B Unclassified GPCRs
C LOTGIDRAFT_127003 hypothetical protein K08469 GPR158; G protein-coupled receptor 158
C LOTGIDRAFT_161509 hypothetical protein K08469 GPR158; G protein-coupled receptor 158
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AFrizzled / Smoothened family
B LOTGIDRAFT_139359 hypothetical protein K02432 FZD1_7; frizzled 1/7
B LOTGIDRAFT_201339 hypothetical protein K02354 FZD4; frizzled 4
B LOTGIDRAFT_200873 hypothetical protein K02375 FZD5_8; frizzled 5/8
B LOTGIDRAFT_228923 hypothetical protein K02842 FZD9_10; frizzled 9/10
B LOTGIDRAFT_195892 hypothetical protein K06226 SMO; smoothened
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AOthers
B Chemoreception
C Olfactory
C Taste
C Vomeronasal pheromone
C Insect odorant and taste
D LOTGIDRAFT_152656 hypothetical protein K08471 GR; gustatory receptor
D LOTGIDRAFT_168741 hypothetical protein K08471 GR; gustatory receptor
C Nematode chemoreception
C Fungal mating pheromone
B Others
C Ocular albinism proteins
D LOTGIDRAFT_205062 hypothetical protein K08470 OA1; ocular albinism type 1 protein
D LOTGIDRAFT_163315 hypothetical protein K08470 OA1; ocular albinism type 1 protein
C Neuronostatin
D LOTGIDRAFT_200945 hypothetical protein K22985 GPR107; G protein-coupled receptor 107
C Plant Mlo receptors
C cAMP signaling
D LOTGIDRAFT_158835 hypothetical protein K22987 GCR1; cAMP receptor-like G-protein coupled receptor
C Bacterial rhodopsin
C Orphan GPCRs
D LOTGIDRAFT_124095 hypothetical protein K22988 TPRA1; transmembrane protein adipocyte-associated 1
D LOTGIDRAFT_192257 hypothetical protein K22989 GPR137; integral membrane protein GPR137
!
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: December 8, 2022
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Classification taken and modified from GPCRDB