+F Repair protein KO
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DNA Repair and Recombination Proteins - Leptospira interrogans serovar Copenhageni
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D LIC_11339 phr; deoxyribodipyrimidine photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E LIC_13102 uracil DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E LIC_11614 mutY; A/G specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E LIC_11759 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
E LIC_11791 recG; ATP-dependent DNA helicase K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
D LIC_11687 endonuclease K05986 NUCS; nuclease S1 [EC:3.1.30.1]
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D LIC_12191 mutT; mutator protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D LIC_20067 MutT-like protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D LIC_12560 dut; deoxyuridine 5'triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D LIC_13402 ada; methylated-DNA--protein-cysteine methyltransferase transcription regulator K10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response / methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]
D LIC_11339 phr; deoxyribodipyrimidine photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E LIC_13102 uracil DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E LIC_10548 uracil-DNA glycosylase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E LIC_10238 3-methyladenine DNA glycosylase K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E LIC_12362 alkA; 3-methyladenine DNA glycosylase K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E LIC_11614 mutY; A/G specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E LIC_13064 tag; 3-methyl-adenine DNA glycosylase I K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E LIC_11759 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E LIC_11452 exodeoxyribonuclease K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D RecJ
E LIC_11066 recJ; single-stranded DNA exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E LIC_13282 lig; NAD dependent DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E LIC_10586 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E LIC_11717 uvrA; nucleotide excision repair subunit A UVRABC K03701 uvrA; excinuclease ABC subunit A
E LIC_12941 uvrB; nucleotide excision repair subunit B K03702 uvrB; excinuclease ABC subunit B
E LIC_11756 uvrC; nucleotide excision repair subunit C K03703 uvrC; excinuclease ABC subunit C
E LIC_11624 uvrD; ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E LIC_11732 uvrD2; atp-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E LIC_10420 DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E LIC_12588 ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E LIC_10586 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E LIC_13282 lig; NAD dependent DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F LIC_10753 rpoB; RNA polymerase beta subunit K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F LIC_10754 rpoC; DNA-directed RNA polymerase beta' chain protein K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F LIC_12846 rpoA; DNA-directed RNA polymerase alpha chain K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F LIC_11455 mfd; transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E LIC_11774 mutS; DNA mismatch repair protein K03555 mutS; DNA mismatch repair protein MutS
D Molecular matchmaker
E LIC_12514 mutL; DNA mismatch repair protein K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
D DNA exonucleases
E LIC_11591 xseA; exodeoxyribonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E LIC_11590 exodeoxyribonuclease small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E LIC_10222 dnaE; DNA polymerase III alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E LIC_10002 dnaN; DNA polymerase III beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E LIC_10014 conserved hypothetical protein K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E LIC_13474 dnaX; DNA polymerase III gamma subunit K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
E LIC_13497 DNA polymerase III subunit-related protein K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E LIC_13282 lig; NAD dependent DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E LIC_11624 uvrD; ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E LIC_11732 uvrD2; atp-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E LIC_10420 DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E LIC_12588 ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E LIC_10564 single-strand DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E LIC_12112 ssb; single-stranded DNA binding protein K03111 ssb; single-strand DNA-binding protein
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E LIC_12686 recB; exodeoxyribonuclease V beta chain K03582 recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5]
E LIC_12688 recC; exodeoxyribonuclease v gamma chain K03583 recC; exodeoxyribonuclease V gamma subunit [EC:3.1.11.5]
E LIC_12685 recD; exodeoxyribonuclease v alpha chain K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E LIC_11745 recA; recombinase A K03553 recA; recombination protein RecA
E LIC_11148 ruvA; DNA helicase subunit A K03550 ruvA; holliday junction DNA helicase RuvA
E LIC_12811 ruvB; holliday junction DNA helicase protein K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E LIC_12885 ruvC; putative holliday junction endodeoxyribonuclease protein K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E LIC_11551 priA; primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
D RecFOR pathway proteins
E LIC_11745 recA; recombinase A K03553 recA; recombination protein RecA
E LIC_11142 radA; RadA K04485 radA; DNA repair protein RadA/Sms
E LIC_10003 recF; DNA repair and genetic recombination protein K03629 recF; DNA replication and repair protein RecF
E LIC_13150 ATP-dependent DNA helicase protein K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E LIC_11066 recJ; single-stranded DNA exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E LIC_12104 recO; RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E LIC_13476 recR; RecR K06187 recR; recombination protein RecR
E LIC_11620 recN; DNA repair protein K03631 recN; DNA repair protein RecN (Recombination protein N)
E LIC_11148 ruvA; DNA helicase subunit A K03550 ruvA; holliday junction DNA helicase RuvA
E LIC_12811 ruvB; holliday junction DNA helicase protein K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E LIC_12885 ruvC; putative holliday junction endodeoxyribonuclease protein K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
D Other HR factor
E LIC_10942 conserved hypothetical protein K15342 cas1; CRISP-associated protein Cas1
D Archaeal homologous recombinant proteins
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
E LIC_12677 ATP-dependent DNA ligase K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1]
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F LIC_10006 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F LIC_13347 DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F LIC_10005 DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F LIC_13348 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F LIC_12080 topA; DNA topoisomerase I protein K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F LIC_11066 recJ; single-stranded DNA exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F LIC_12104 recO; RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F LIC_13476 recR; RecR K06187 recR; recombination protein RecR
F LIC_13282 lig; NAD dependent DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
E Supressor
F LIC_12961 recQ; ATP-dependent DNA helicase K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F LIC_12689 ATP-dependent DNA helicase K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F LIC_11717 uvrA; nucleotide excision repair subunit A UVRABC K03701 uvrA; excinuclease ABC subunit A
F LIC_12941 uvrB; nucleotide excision repair subunit B K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D LIC_13052 dinP; DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
C Other SOS response factors
D LIC_11745 recA; recombinase A K03553 recA; recombination protein RecA
D LIC_12305 lexA; transcriptional repressor (LexA family) K01356 lexA; repressor LexA [EC:3.4.21.88]
D LIC_12654 transcriptional repressor (LexA family) K01356 lexA; repressor LexA [EC:3.4.21.88]
D LIC_11620 recN; DNA repair protein K03631 recN; DNA repair protein RecN (Recombination protein N)
D LIC_10564 single-strand DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D LIC_12112 ssb; single-stranded DNA binding protein K03111 ssb; single-strand DNA-binding protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D LIC_12019 yoaA; ATP-dependent helicase K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
C Modulation of nucleotide pools
D LIC_12191 mutT; mutator protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D LIC_20067 MutT-like protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D LIC_12560 dut; deoxyuridine 5'triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D LIC_11587 nrdA; ribonucleotide reductase protein K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024