+C Lipid biosynthesis protein KO #

  Lipid Biosynthesis Proteins - Mycobacterium tuberculosis variant bovis BCG Pasteur 1173P2

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AFatty acid synthase B Animal type B Yeast type B Bacteria type C BCG_2545c fas; Probable fatty acid synthase fas K11533 fas; fatty acid synthase, bacteria type [EC:2.3.1.-] B Component type C BCG_0698 fabD2; Putative malonyl coa-acyl carrier protein Transacylase fabD2 K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39] C BCG_2260 fabD; Malonyl CoA-acyl carrier protein transacylase fabD K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39] C BCG_0443 pks6a; Probable membrane bound polyketide synthase pks6a [first part] K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179] C BCG_0280c fabG4; Probable 3-oxoacyl-[acyl-carrier protein] reductase fabG4 K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] C BCG_1412 fabG2; Putative 3-oxoacyl-[acyl-carrier protein] reductase fabG2 K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] C BCG_3623c Putative oxidoreductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] C BCG_1656 tesB1; Probable acyl-CoA thioesterase II tesB1 K10805 tesB; acyl-CoA thioesterase II [EC:3.1.2.-] C BCG_2630c tesB2; Probable acyl-CoA thioesterase II tesB2 K10805 tesB; acyl-CoA thioesterase II [EC:3.1.2.-] C BCG_0577c fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III fabH K11608 mtfabH; mycobacterial beta-ketoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.301] C BCG_2262 kasA; 3-oxoacyl-[acyl-carrier protein] synthase 1 kasA K11609 kasA; meromycolic acid 3-oxoacyl-(acyl carrier protein) synthase I [EC:2.3.1.293] C BCG_2263 kasB; 3-oxoacyl-[acyl-carrier protein] synthase 2 kasB K27070 kasB; meromycolic acid 3-oxoacyl-(acyl carrier protein) synthase II [EC:2.3.1.294] C BCG_1545 fabG1; Probable 3-oxoacyl-[acyl-carrier protein] reductase fabG1 K11610 mabA; beta-ketoacyl ACP reductase [EC:1.1.1.100] C BCG_0684 Conserved hypothetical protein K27071 hadA; meromycolic acid (3R)-3-hydroxyacyl-[acyl carrier protein] dehydratase HadA [EC:4.2.1.-] C BCG_0685 Conserved hypothetical protein K27072 hadB; meromycolic acid (3R)-3-hydroxyacyl-[acyl carrier protein] dehydratase HadB [EC:4.2.1.-] C BCG_0686 Conserved hypothetical protein K27073 hadC; meromycolic acid (3R)-3-hydroxyacyl-[acyl carrier protein] dehydratase HadC [EC:4.2.1.-] C BCG_0547c Conserved hypothetical protein K27074 hadD; meromycolic acid (3R)-3-hydroxyacyl-[acyl carrier protein] dehydratase HadD [EC:4.2.1.-] C BCG_1546 inhA; NADH-dependent enoyl-[acyl-carrier-protein] reductase inhA K11611 inhA; meromycolic acid enoyl-[acyl-carrier-protein] reductase [EC:1.3.1.118] # ADesaturase B First C BCG_0877c desA1; Probable acyl-[acyl-carrier protein] desaturase desA1 K03921 FAB2; acyl-[acyl-carrier-protein] desaturase [EC:1.14.19.2 1.14.19.11 1.14.19.26] C BCG_1154 desA2; Possible acyl-[acyl-carrier protein] desaturase desA2 K03922 desA2; acyl-[acyl-carrier-protein] desaturase [EC:1.14.19.2] C BCG_3259c desA3_1; Possible linoleoyl-CoA desaturase K22769 desA3; NADPH-dependent stearoyl-CoA 9-desaturase [EC:1.14.19.-] C BCG_3352c desA3_2; Possible linoleoyl-CoA desaturase desA3 K22769 desA3; NADPH-dependent stearoyl-CoA 9-desaturase [EC:1.14.19.-] B Omega B Front-end B Sphingolipid B Other # AElongase B LCFA B PUFA B Unclassified # APolyketide synthase B Modular PKS C BCG_2962c mas; Probable multifunctional mycocerosic acid synthase membrane-associated mas K11628 mas; mycocerosic acid synthase [EC:2.3.1.111] C BCG_2968c pks1; Probable polyketide synthase pks1 K12430 pks1_15; 4-hydroxyphenylalkanoate synthase [EC:2.3.1.261] C BCG_3888c pks2; Polyketide synthase pks2 K12431 pks2; phthioceranic/hydroxyphthioceranic acid synthase [EC:2.3.1.287] C BCG_2067c pks12; Probable polyketide synthase pks12 K12436 pks12; mycoketide-CoA synthase [EC:2.3.1.295] C BCG_3862c pks13; Polyketide synthase pks13 K12437 pks13; polyketide synthase 13 C BCG_2953 ppsA; Phenolpthiocerol synthesis type-I polyketide synthase ppsA K12440 ppsA; phthiocerol/phenolphthiocerol synthesis type-I polyketide synthase A [EC:2.3.1.292] C BCG_2954 ppsB; Phenolpthiocerol synthesis type-I polyketide synthase ppsB K12441 ppsB; phthiocerol/phenolphthiocerol synthesis type-I polyketide synthase B [EC:2.3.1.292] C BCG_2955 ppsC; Phenolpthiocerol synthesis type-I polyketide synthase ppsC K12442 ppsC; phthiocerol/phenolphthiocerol synthesis type-I polyketide synthase C [EC:2.3.1.292] C BCG_2956 ppsD; Phenolpthiocerol synthesis type-I polyketide synthase ppsD K12443 ppsD; phthiocerol/phenolphthiocerol synthesis type-I polyketide synthase D [EC:2.3.1.292] C BCG_2957 ppsE; Phenolpthiocerol synthesis type-I polyketide synthase ppsE K12444 ppsE; phthiocerol/phenolphthiocerol synthesis type-I polyketide synthase E [EC:2.3.1.292] B Component type C BCG_2396c mbtC; Polyketide synthetase mbtC K04790 mbtC; mycobactin polyketide synthetase MbtC C BCG_2395c mbtD; Polyketide synthetase mbtD K04791 mbtD; mycobactin polyketide synthetase MbtD # AAcyl-CoA synthetase B Short/medium chain acyl-CoA synthetase C BCG_3725 acs; acetyl-coenzyme A synthetase acs K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] B Long/very long chain acyl-CoA synthetase C BCG_2203 fadD15; Probable long-chain-fatty-acid-CoA ligase fadD15 K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] C BCG_1721 Possible long-chain acyl-CoA synthase K03822 K03822; putative long chain acyl-CoA synthase [EC:6.2.1.-] C BCG_0132 fadD10; Possible fatty-acid-CoA ligase fadD10 K12422 fadD10; long chain fatty acid CoA ligase FadD10 [EC:6.2.1.-] C BCG_3889 fadD23; Probable fatty-acid-CoA ligase fadD23 K12425 fadD23; long-chain fatty acid adenylase/transferase FadD23 [EC:6.2.1.57] C BCG_2952 fadD26; Fatty-acid-CoA ligase fadD26 K12426 fadD26; long-chain fatty acid adenylase/transferase FadD26 [EC:6.2.1.59] C BCG_2963 fadD28; fatty-acid-CoA ligase fadD28 K12427 fadD28; long-chain fatty acid adenylyltransferase FadD28 [EC:6.2.1.49] C BCG_2971c fadD29; Probable fatty-acid-CoA ligase fadD29 K21059 fadD29; 4-hydroxyphenylalkanoate adenylyltransferase [EC:6.2.1.51] C BCG_1253 fadD36; Probable fatty-acid-CoA ligase fadD36 K12429 fadD36; fatty acid CoA ligase FadD36 B Unknown C BCG_2613 fadD9; Probable fatty-acid-CoA ligase fadD9 K12421 fadD9; fatty acid CoA ligase FadD9 C BCG_1247c fadD21; Probable fatty-acid--CoA ligase fadD21 K12423 fadD21; fatty acid CoA ligase FadD21 C BCG_2969c fadD22; Probable fatty-acid-CoA ligase fadD22 K12424 fadD22; 4-hydroxybenzoate adenylyltransferase [EC:6.2.1.50] C BCG_3863c fadD32; Probable fatty-acid-CoA ligase fadD32 K12428 fadD32; fatty acid CoA ligase FadD32 C BCG_2525c fadD35; Probable fatty-acid-CoA ligase fadD35 K00666 K00666; fatty-acyl-CoA synthase [EC:6.2.1.-] C BCG_1070 pks16; Putative polyketide synthase pks16 K00666 K00666; fatty-acyl-CoA synthase [EC:6.2.1.-] C BCG_0203 fadD5; Probable fatty-acid-CoA ligase fadD5 K00666 K00666; fatty-acyl-CoA synthase [EC:6.2.1.-] C BCG_1964 fadD31; Probable acyl-CoA ligase fadD31 K00666 K00666; fatty-acyl-CoA synthase [EC:6.2.1.-] C BCG_0596c fadD8; Probable fatty-acid-CoA ligase fadD8 K00666 K00666; fatty-acyl-CoA synthase [EC:6.2.1.-] C BCG_1266 fadD6; Probable fatty-acid-CoA ligase fadD6 K00666 K00666; fatty-acyl-CoA synthase [EC:6.2.1.-] C BCG_3570 fadD17; Possible fatty-acid-CoA synthetase fadD17 K00666 K00666; fatty-acyl-CoA synthase [EC:6.2.1.-] C BCG_1789c fadD1; Possible fatty-acid-CoA ligase fadD1 K00666 K00666; fatty-acyl-CoA synthase [EC:6.2.1.-] # APhospholipid acyltransferase B GPAT C BCG_2500c plsB2; Probable glycerol-3-phosphate acyltransferase plsB2 (GPAT) K00631 plsB; glycerol-3-phosphate O-acyltransferase [EC:2.3.1.15] C BCG_1603 plsB1; Possible acyltransferase plsB1 K00631 plsB; glycerol-3-phosphate O-acyltransferase [EC:2.3.1.15] B LPAAT/LPLAT C BCG_2197c 1-acylglycerol-3-phosphate O-acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51] # AOthers B Multifunctional type C BCG_1243 pks3; Probable polyketide beta-ketoacyl synthase pks3 K12432 pks3_4; mycolipanoate synthase [EC:2.3.1.252] C BCG_1579c pks5; Probable polyketide synthase pks5 K12433 pks5; polyketide synthase 5 C BCG_1700 pks7; Probable polyketide synthase pks7 K12434 pks7; polyketide synthase 7 C BCG_1701 pks8; Probable polyketide synthase pks8 K12435 pks8; polyketide synthase 8 C BCG_1702 pks17; Probable polyketide synthase pks17 K12439 pks17; polyketide synthase 17 B Component type C BCG_2974 Conserved hypothetical protein K12445 K12445; trans enoyl reductase [EC:1.3.1.-] ! #
#[ COMPOUND | BRITE | KEGG2 | KEGG ]
#Last updated: November 27, 2023 #
Desaturase/elongase family classification based on Hashimoto et al. (2008)