+E Replication protein KO
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DNA Replication Proteins - Methylobacterium sp. 4-46
%
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AEukaryotic type
B DNA Replication Initiation Factors
C pre-RC (pre-replication complex)
C CDK (cyclin dependent kinase)
C DDK (Dbf-4 dependent kinase)
C GINS complex
C Other initiation factors
B DNA Replication Elongation Factors
C DNA polymerase alpha / primase complex
C DNA polymerase epsilon complex
C DNA polymerase delta complex
C DNA polymerase gamma complex (mitochondrial)
C RPA (replication protein A)
C RFC (replication factor C)
C RNase H
D M446_5247 ribonuclease H K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
C Other elongation factors
B DNA Replication Termination Factors
C DNA methylation enzymes
D M446_1494 DNA-cytosine methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D M446_1487 DNA-cytosine methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
C Prevention of re-replication factors
C Telomere proteins
D Shelterin complex
D TERB1-TERB2-MAJIN complex
D CST complex (animals)
D CST complex (yeast)
D RIF proteins
D SIR proteins
C Telomerase complex (animals)
D Dyskerin complex
C Telomerase complex (fungi)
D Sm core complex
C ELG1-RFC complex
C MRN complex
C Other termination factors
B DNA Topoisomerases
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AProkaryotic type
B DNA Replication Initiation Factors
C Initiation factors (bacterial)
D M446_6231 integration host factor, alpha subunit K04764 ihfA; integration host factor subunit alpha
D M446_2501 integration host factor, beta subunit K05788 ihfB; integration host factor subunit beta
D M446_1007 histone family protein DNA-binding protein K05788 ihfB; integration host factor subunit beta
D M446_3362 histone family protein DNA-binding protein K05788 ihfB; integration host factor subunit beta
D M446_6976 hypothetical protein K05788 ihfB; integration host factor subunit beta
D M446_0001 chromosomal replication initiator protein DnaA K02313 dnaA; chromosomal replication initiator protein
D M446_2594 replicative DNA helicase K02314 dnaB; replicative DNA helicase [EC:5.6.2.3]
D M446_4095 DnaB domain protein helicase domain protein K02314 dnaB; replicative DNA helicase [EC:5.6.2.3]
D M446_6776 DNA primase K02316 dnaG; DNA primase [EC:2.7.7.101]
D M446_4448 single-strand binding protein K03111 ssb; single-strand DNA-binding protein
C Initiation factors (archaeal)
B DNA Replication Elongation Factors
C Elongation factors (bacterial)
D DNA polymerase III holoenzyme
E M446_5992 DNA polymerase III, alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E M446_0002 DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E M446_5406 DNA polymerase III chi subunit HolC K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
E M446_1406 DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E M446_6279 DNA-directed DNA polymerase K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E M446_1400 Exonuclease RNase T and DNA polymerase III K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E M446_1033 DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E M446_0045 Exonuclease RNase T and DNA polymerase III K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E M446_6601 Exonuclease RNase T and DNA polymerase III K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E M446_1688 Exonuclease RNase T and DNA polymerase III K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E M446_1507 DNA-directed DNA polymerase K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
E M446_4243 DNA polymerase III, subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D RNase H
E M446_5247 ribonuclease H K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
E M446_5363 Ribonuclease H K03470 rnhB; ribonuclease HII [EC:3.1.26.4]
D Other elongation factors
E M446_0678 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E M446_1689 DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
C Elongation factors (archaeal)
D B-family DNA polymerases
D D-family DNA polymerases
D RNase H
E M446_5247 ribonuclease H K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
E M446_5363 Ribonuclease H K03470 rnhB; ribonuclease HII [EC:3.1.26.4]
D RFC (replication factor C)
D Other elongation factors
B DNA Replication Termination Factors
C Terminus site-binding protein
C DNA methylation enzymes
C Prevention of re-replication factors
B DNA Topoisomerases
C M446_4447 DNA gyrase, A subunit K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
C M446_5333 DNA gyrase, B subunit K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
C M446_4317 DNA topoisomerase IV, A subunit K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2]
C M446_4352 DNA topoisomerase IV, B subunit K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2]
C M446_4350 DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
C M446_5045 putative DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
C M446_4204 DNA topoisomerase type IA central domain protein K03169 topB; DNA topoisomerase III [EC:5.6.2.1]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: November 2, 2022