+E Messenger RNA Biogenesis KO
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Messenger RNA Biogenesis - Myotis brandtii (Brandt's bat)
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AEukaryotic type
B mRNA processing factors
C 5' end processing
D Capping factors
E 102243455 RNMT; RNA guanine-7 methyltransferase K00565 RNMT; mRNA (guanine-N7-)-methyltransferase [EC:2.1.1.56]
E 102249374 RNGTT; RNA guanylyltransferase and 5'-phosphatase K13917 RNGTT; mRNA-capping enzyme [EC:2.7.7.50 3.6.1.74]
E 102244078 CDK7; cyclin dependent kinase 7 K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
E 102261455 UBAC2; UBA domain containing 2 K14589 CMTR1; cap1 methyltransferase [EC:2.1.1.57]
E 102239315 CMTR1; cap methyltransferase 1 K14589 CMTR1; cap1 methyltransferase [EC:2.1.1.57]
E 102252269 CMTR2; cap methyltransferase 2 K14590 CMTR2; cap2 methyltransferase [EC:2.1.1.296]
E 102249675 FAM103A1; family with sequence similarity 103 member A1 K18708 FAM103A1; RNMT-activating mini protein
D Cap binding complex
E 102240142 NCBP1; nuclear cap binding protein subunit 1 K12882 NCBP1; nuclear cap-binding protein subunit 1
E 102250745 NCBP2; nuclear cap binding protein subunit 2 K12883 NCBP2; nuclear cap-binding protein subunit 2
C 3' end processing
D Pre-mRNA cleavage factor Im (CFIm)
E 102240360 cleavage and polyadenylation specificity factor subunit 5 K14397 NUDT21; cleavage and polyadenylation specificity factor subunit 5
E 102246151 cleavage and polyadenylation specificity factor subunit 5 K14397 NUDT21; cleavage and polyadenylation specificity factor subunit 5
E 102241518 NUDT21; nudix hydrolase 21 K14397 NUDT21; cleavage and polyadenylation specificity factor subunit 5
E 102257629 CPSF7; cleavage and polyadenylation specific factor 7 K14398 CPSF6_7; cleavage and polyadenylation specificity factor subunit 6/7
E 102258940 CPSF6; cleavage and polyadenylation specific factor 6 K14398 CPSF6_7; cleavage and polyadenylation specificity factor subunit 6/7
E 102241108 cleavage and polyadenylation specificity factor subunit 6 K14398 CPSF6_7; cleavage and polyadenylation specificity factor subunit 6/7
D Pre-mRNA cleavage factor IIm (CFIIm)
E 102247153 CLP1; cleavage and polyadenylation factor I subunit 1 K14399 CLP1; polyribonucleotide 5'-hydroxyl-kinase [EC:2.7.1.78]
E 102240760 polyribonucleotide 5'-hydroxyl-kinase Clp1 K14399 CLP1; polyribonucleotide 5'-hydroxyl-kinase [EC:2.7.1.78]
E 102263490 PCF11; PCF11 cleavage and polyadenylation factor subunit K14400 PCF11; pre-mRNA cleavage complex 2 protein Pcf11
E 102259861 pre-mRNA cleavage complex 2 protein Pcf11-like K14400 PCF11; pre-mRNA cleavage complex 2 protein Pcf11
D Cleavage and polyadenylation specificity factor (CPSF) complex
E 102239185 CPSF1; cleavage and polyadenylation specific factor 1 K14401 CPSF1; cleavage and polyadenylation specificity factor subunit 1
E 102256303 CPSF2; cleavage and polyadenylation specific factor 2 K14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2
E 102247452 CPSF3; cleavage and polyadenylation specific factor 3 K14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]
E 102242119 CPSF4L; cleavage and polyadenylation specific factor 4 like K14404 CPSF4; cleavage and polyadenylation specificity factor subunit 4
E 102239941 CPSF4; cleavage and polyadenylation specific factor 4 K14404 CPSF4; cleavage and polyadenylation specificity factor subunit 4
E 102263042 FIP1L1; factor interacting with PAPOLA and CPSF1 K14405 FIP1L1; pre-mRNA 3'-end-processing factor FIP1
E 102247893 WDR33; WD repeat domain 33 K15542 PFS2; polyadenylation factor subunit 2
E 102249598 WDR82; WD repeat domain 82 K14962 WDR82; COMPASS component SWD2
E 102244214 PPP1CA; protein phosphatase 1 catalytic subunit alpha K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E 102253559 serine/threonine-protein phosphatase PP1-gamma catalytic subunit K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E 102248545 PPP1CB; protein phosphatase 1 catalytic subunit beta K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E 102239740 PPP1CC; protein phosphatase 1 catalytic subunit gamma K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E 102240937 SSU72; SSU72 homolog, RNA polymerase II CTD phosphatase K15544 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16]
E 102261904 RNA polymerase II subunit A C-terminal domain phosphatase SSU72 K15544 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16]
E 102248276 RNA polymerase II subunit A C-terminal domain phosphatase SSU72 K15544 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16]
E 102261660 RNA polymerase II subunit A C-terminal domain phosphatase SSU72 K15544 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16]
E 102254690 RNA polymerase II subunit A C-terminal domain phosphatase SSU72 K15544 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16]
D Cleavage stimulation factor (CSTF) complex
E 102240289 CSTF1; cleavage stimulation factor subunit 1 K14406 CSTF1; cleavage stimulation factor subunit 1
E 102248774 cleavage stimulation factor subunit 1 K14406 CSTF1; cleavage stimulation factor subunit 1
E 102252322 CSTF2; cleavage stimulation factor subunit 2 K14407 CSTF2; cleavage stimulation factor subunit 2
E 102254131 CSTF2T; cleavage stimulation factor subunit 2 tau variant K14407 CSTF2; cleavage stimulation factor subunit 2
E 102262249 cleavage stimulation factor subunit 2 tau variant-like K14407 CSTF2; cleavage stimulation factor subunit 2
E 102251398 CSTF3; cleavage stimulation factor subunit 3 K14408 CSTF3; cleavage stimulation factor subunit 3
E 102248403 SYMPK; symplekin K06100 SYMPK; symplekin
D U7-dependent histone pre-mRNA processing factors
E 102260822 SNRPB; small nuclear ribonucleoprotein polypeptides B and B1 K11086 SNRPB; small nuclear ribonucleoprotein B and B'
E 102239915 small nuclear ribonucleoprotein Sm D3 K11088 SNRPD3; small nuclear ribonucleoprotein D3
E 102240227 small nuclear ribonucleoprotein Sm D3 K11088 SNRPD3; small nuclear ribonucleoprotein D3
E 102261622 SNRPE; small nuclear ribonucleoprotein polypeptide E K11097 SNRPE; small nuclear ribonucleoprotein E
E 102256920 small nuclear ribonucleoprotein E K11097 SNRPE; small nuclear ribonucleoprotein E
E 102247222 SNRPF; small nuclear ribonucleoprotein polypeptide F K11098 SNRPF; small nuclear ribonucleoprotein F
E 102243246 small nuclear ribonucleoprotein F K11098 SNRPF; small nuclear ribonucleoprotein F
E 102248904 small nuclear ribonucleoprotein F-like K11098 SNRPF; small nuclear ribonucleoprotein F
E 102249731 SNRPG; small nuclear ribonucleoprotein polypeptide G K11099 SNRPG; small nuclear ribonucleoprotein G
E 102248195 small nuclear ribonucleoprotein G K11099 SNRPG; small nuclear ribonucleoprotein G
E 102239601 LSM10; LSM10, U7 small nuclear RNA associated K25591 LSM10; U7 snRNA-associated Sm-like protein LSm10
E 102246855 LSM11; LSM11, U7 small nuclear RNA associated K25592 LSM11; U7 snRNA-associated Sm-like protein LSm11
E 102256303 CPSF2; cleavage and polyadenylation specific factor 2 K14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2
E 102247452 CPSF3; cleavage and polyadenylation specific factor 3 K14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]
E 102252322 CSTF2; cleavage stimulation factor subunit 2 K14407 CSTF2; cleavage stimulation factor subunit 2
E 102254131 CSTF2T; cleavage stimulation factor subunit 2 tau variant K14407 CSTF2; cleavage stimulation factor subunit 2
E 102262249 cleavage stimulation factor subunit 2 tau variant-like K14407 CSTF2; cleavage stimulation factor subunit 2
E 102248403 SYMPK; symplekin K06100 SYMPK; symplekin
E 102253298 CASP8AP2; caspase 8 associated protein 2 K25593 CASP8AP2; CASP8-associated protein 2
D DRB sensitivity inducing factor (DSIF) complex
E 102241277 SUPT4H1; SPT4 homolog, DSIF elongation factor subunit K15171 SUPT4H1; transcription elongation factor SPT4
E 102258365 transcription elongation factor SPT4-A K15171 SUPT4H1; transcription elongation factor SPT4
E 102257379 transcription elongation factor SPT4-A-like K15171 SUPT4H1; transcription elongation factor SPT4
E 102249428 transcription elongation factor SPT4-A K15171 SUPT4H1; transcription elongation factor SPT4
E 102257813 SUPT5H; SPT5 homolog, DSIF elongation factor subunit K15172 SUPT5H; transcription elongation factor SPT5
D N6-methyltransferase complex
E 102257958 METTL3; methyltransferase like 3 K05925 METTL3; mRNA m6A methyltransferase catalytic subunit [EC:2.1.1.348]
E 102248922 METTL14; methyltransferase like 14 K23960 METTL14; mRNA m6A methyltransferase non-catalytic subunit
E 102259015 METTL4; methyltransferase like 4 K24174 METTL4; N(6)-adenine-specific DNA methyltransferase [EC:2.1.1.72]
E 102245762 METTL16; methyltransferase like 16 K11393 METTL16; U6 snRNA m6A methyltransferase [EC:2.1.1.346]
E 102261504 WTAP; Wilms tumor 1 associated protein K22824 WTAP; pre-mRNA-splicing regulator WTAP
E 102248190 KIAA1429 ortholog K22910 VIRMA; protein virilizer
E 102240502 RBM15B; RNA binding motif protein 15B K13190 RBM15; RNA-binding protein 15
E 102243118 RBM15; RNA binding motif protein 15 K13190 RBM15; RNA-binding protein 15
E 102251280 ZC3H13; zinc finger CCCH-type containing 13 K22909 ZC3H13; zinc finger CCCH domain-containing protein 13
E 102249676 CBLL1; Cbl proto-oncogene like 1 K15685 CBLL1; E3 ubiquitin-protein ligase Hakai [EC:2.3.2.27]
E 106726866 ZNF645; zinc finger protein 645 K15685 CBLL1; E3 ubiquitin-protein ligase Hakai [EC:2.3.2.27]
D Poly(A) addition factors
E 102247943 PAPOLA; poly(A) polymerase alpha K14376 PAP; poly(A) polymerase [EC:2.7.7.19]
E 102260295 PAPOLG; poly(A) polymerase gamma K14376 PAP; poly(A) polymerase [EC:2.7.7.19]
E 102255131 PAPOLB; poly(A) polymerase beta K14376 PAP; poly(A) polymerase [EC:2.7.7.19]
E 102247687 PAPD4; poly(A) RNA polymerase D4, non-canonical K14079 PAPD4; poly(A) RNA polymerase GLD2 [EC:2.7.7.19]
E 102252524 TUT1; terminal uridylyl transferase 1, U6 snRNA-specific K18709 TUT1; speckle targeted PIP5K1A-regulated poly(A) polymerase [EC:2.7.7.19 2.7.7.52]
D Negative regulators of mRNA 3' end processing
E 102247141 BARD1; BRCA1 associated RING domain 1 K10683 BARD1; BRCA1-associated RING domain protein 1
E 102244758 RBM26; RNA binding motif protein 26 K13192 RBM26; RNA-binding protein 26
E 102242623 FTO; FTO, alpha-ketoglutarate dependent dioxygenase K19469 FTO; mRNA N6-methyladenine demethylase [EC:1.14.11.53]
E 102257315 ALKBH5; alkB homolog 5, RNA demethylase K10767 ALKBH5; mRNA N6-methyladenine demethylase [EC:1.14.11.53]
E 102240030 TARDBP; TAR DNA binding protein K23600 TARDBP; TAR DNA-binding protein 43
C Other processing factors
D 102257249 DHX40; DEAH-box helicase 40 K18711 DHX40; ATP-dependent RNA helicase DHX40 [EC:5.6.2.6]
D 102244019 KIN; Kin17 DNA and RNA binding protein K13102 KIN; DNA/RNA-binding protein KIN17
D 102256536 METTL8; methyltransferase like 8 K24975 METTL8; mRNA N(3)-methylcytidine methyltransferase METTL8 [EC:2.1.1.-]
D 102246352 METTL22; methyltransferase like 22 K23040 METTL22; methyltransferase-like protein 22 [EC:2.1.1.-]
D 102243204 FAM46B; family with sequence similarity 46 member B K23033 TENT5A_B; terminal nucleotidyltransferase 5A/B [EC:2.7.7.-]
D 102262950 FAM46C; family with sequence similarity 46 member C K23034 TENT5C; terminal nucleotidyltransferase 5C [EC:2.7.7.19]
D 102253602 protein FAM46D K23035 TENT5D; terminal nucleotidyltransferase 5D [EC:2.7.7.19]
D 102245236 ZC3H14; zinc finger CCCH-type containing 14 K23038 ZC3H14; zinc finger CCCH domain-containing protein 14
D 102260255 SRRT; serrate, RNA effector molecule K27103 SRRT; serrate RNA effector molecule
B mRNA surveillance and transport factors
C Transport factors
D EJC complex
E 102259389 RBM8A; RNA binding motif protein 8A K12876 RBM8A; RNA-binding protein 8A
E 102249642 RNA-binding protein 8A-like K12876 RBM8A; RNA-binding protein 8A
E 102262492 RNA-binding protein 8A-like K12876 RBM8A; RNA-binding protein 8A
E 102258528 MAGOHB; mago homolog B, exon junction complex core component K12877 MAGOH; protein mago nashi
E 102259745 MAGOH; mago homolog, exon junction complex core component K12877 MAGOH; protein mago nashi
E 102263097 THO complex subunit 4 K12881 THOC4; THO complex subunit 4
E 102263396 THO complex subunit 4 K12881 THOC4; THO complex subunit 4
E 102247725 ALYREF; Aly/REF export factor K12881 THOC4; THO complex subunit 4
E 102253817 THO complex subunit 4 K12881 THOC4; THO complex subunit 4
E 102239713 THO complex subunit 4 K12881 THOC4; THO complex subunit 4
E 102249384 DDX39B; DExD-box helicase 39B K12812 DDX39B; ATP-dependent RNA helicase UAP56/SUB2 [EC:5.6.2.7]
E 102261425 EIF4A3; eukaryotic translation initiation factor 4A3 K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]
E 102248439 CCDC174; coiled-coil domain containing 174 K25178 CCDC174; coiled-coil domain-containing protein 174
E 102247907 CASC3; cancer susceptibility candidate 3 K14323 CASC3; protein CASC3
E 102263062 SAP18; Sin3A associated protein 18 K14324 SAP18; histone deacetylase complex subunit SAP18
E 102260368 histone deacetylase complex subunit SAP18-like K14324 SAP18; histone deacetylase complex subunit SAP18
E 102261107 PNN; pinin, desmosome associated protein K13114 PNN; pinin
E 102254655 ACIN1; apoptotic chromatin condensation inducer 1 K12875 ACIN1; apoptotic chromatin condensation inducer in the nucleus
E 102258718 RNPS1; RNA binding protein with serine rich domain 1 K14325 RNPS1; RNA-binding protein with serine-rich domain 1
E 102246871 SRRM1; serine and arginine repetitive matrix 1 K13171 SRRM1; serine/arginine repetitive matrix protein 1
D TREX complex
E 102239888 THOC1; THO complex 1 K12878 THOC1; THO complex subunit 1
E 102246100 THO complex subunit 1 K12878 THOC1; THO complex subunit 1
E 102246661 THOC2; THO complex 2 K12879 THOC2; THO complex subunit 2
E 102243933 THO complex subunit 2-like K12879 THOC2; THO complex subunit 2
E 102263604 THO complex subunit 3 K12880 THOC3; THO complex subunit 3
E 102239968 THOC3; THO complex 3 K12880 THOC3; THO complex subunit 3
E 102263097 THO complex subunit 4 K12881 THOC4; THO complex subunit 4
E 102263396 THO complex subunit 4 K12881 THOC4; THO complex subunit 4
E 102247725 ALYREF; Aly/REF export factor K12881 THOC4; THO complex subunit 4
E 102253817 THO complex subunit 4 K12881 THOC4; THO complex subunit 4
E 102239713 THO complex subunit 4 K12881 THOC4; THO complex subunit 4
E 102255297 THOC5; THO complex 5 K13174 THOC5; THO complex subunit 5
E 102242038 THOC6; THO complex 6 K13175 THOC6; THO complex subunit 6
E 102243374 THOC7; THO complex 7 K13176 THOC7; THO complex subunit 7
D TREX-2 complex
E 102259382 PCID2; PCI domain containing 2 K23801 PCID2; nuclear mRNA export protein PCID2/THP1
E 102247806 SEM1; SEM1, 26S proteasome complex subunit K10881 SHFM1; 26 proteasome complex subunit DSS1
E 102244633 ENY2; ENY2, transcription and export complex 2 subunit K11368 ENY2; enhancer of yellow 2 transcription factor
E 102258421 CETN2; centrin 2 K10840 CETN2; centrin-2
E 102259149 centrin-2 K10840 CETN2; centrin-2
E 102245029 centrin-2-like K10840 CETN2; centrin-2
E 102250336 CETN3; centrin 3 K16466 CETN3; centrin-3
E 102244465 MCM3AP; minichromosome maintenance complex component 3 associated protein K24317 MCM3AP; germinal-center associated nuclear protein [EC:2.3.1.48]
D Nuclear pore complex
E 102261375 TPR; translocated promoter region, nuclear basket protein K09291 TPR; nucleoprotein TPR
E 102263463 RAE1; ribonucleic acid export 1 K14298 RAE1; mRNA export factor
E 102261589 SEC13; SEC13 homolog, nuclear pore and COPII coat complex component K14004 SEC13; protein transport protein SEC13
E 102253756 NUP37; nucleoporin 37 K14302 NUP37; nuclear pore complex protein Nup37
E 102243251 NUP85; nucleoporin 85 K14304 NUP85; nuclear pore complex protein Nup85
E 102250713 NUP43; nucleoporin 43 K14305 NUP43; nuclear pore complex protein Nup43
E 102253574 NUP50; nucleoporin 50 K14295 NUP50; nuclear pore complex protein Nup50
E 102242679 NUP54; nucleoporin 54 K14308 NUP54; nuclear pore complex protein Nup54
E 102264059 nuclear pore glycoprotein p62 K14306 NUP62; nuclear pore complex protein Nup62
E 102243609 NUP88; nucleoporin 88 K14318 NUP88; nuclear pore complex protein Nup88
E 102245241 NUP93; nucleoporin 93 K14309 NUP93; nuclear pore complex protein Nup93
E 102259809 NUP98; nucleoporin 98 K14297 NUP98; nuclear pore complex protein Nup98-Nup96
E 102255208 NUP107; nucleoporin 107 K14301 NUP107; nuclear pore complex protein Nup107
E 102239628 NUP133; nucleoporin 133 K14300 NUP133; nuclear pore complex protein Nup133
E 102246199 NUP188; nucleoporin 188 K14311 NUP188; nuclear pore complex protein Nup188
E 102257949 NUP153; nucleoporin 153 K14296 NUP153; nuclear pore complex protein Nup153
E 102259521 NUP155; nucleoporin 155 K14312 NUP155; nuclear pore complex protein Nup155
E 102247272 NUP160; nucleoporin 160 K14303 NUP160; nuclear pore complex protein Nup160
E 102259638 NUP35; nucleoporin 35 K14313 NUP35; nuclear pore complex protein Nup53
E 102249285 NUP205; nucleoporin 205 K14310 NUP205; nuclear pore complex protein Nup205
E 102250728 NUP210L; nucleoporin 210 like K14314 NUP210; nuclear pore complex protein Nup210
E 102247256 NUP210; nucleoporin 210 K14314 NUP210; nuclear pore complex protein Nup210
E 102251677 NUP214; nucleoporin 214 K14317 NUP214; nuclear pore complex protein Nup214
E 102249141 POM121L2; POM121 transmembrane nucleoporin like 2 K14316 POM121; nuclear pore complex protein Nup121
E 102242909 POM121C; nuclear envelope pore membrane protein POM 121C K14316 POM121; nuclear pore complex protein Nup121
E 102264026 NUP58; nucleoporin 58 K14307 NUPL1; nucleoporin p58/p45
E 102240845 NUPL2; nucleoporin like 2 K14321 NUPL2; nucleoporin-like protein 2
E 102260556 NDC1; NDC1 transmembrane nucleoporin K14315 NDC1; nucleoporin NDC1
E 102245284 nucleoporin NDC1 K14315 NDC1; nucleoporin NDC1
E 102260107 SEH1L; SEH1 like nucleoporin K14299 SEH1; nucleoporin SEH1
E 102261459 RANBP2; RAN binding protein 2 K12172 RANBP2; E3 SUMO-protein ligase RanBP2 [EC:2.3.2.-]
E 102264070 SENP2; SUMO1/sentrin/SMT3 specific peptidase 2 K03345 SENP2; sentrin-specific protease 2 (axin associating molecule) [EC:3.4.22.68]
E 102257309 AAAS; aladin WD repeat nucleoporin K14320 AAAS; aladin
E 102250336 CETN3; centrin 3 K16466 CETN3; centrin-3
E 102245509 nucleoporin GLE1 K18723 GLE1; nucleoporin GLE1
E 102251471 GLE1; GLE1, RNA export mediator K18723 GLE1; nucleoporin GLE1
E 102258513 nuclear RNA export factor 2 K14284 NXF; nuclear RNA export factor
E 102239377 NXF3; nuclear RNA export factor 3 K14284 NXF; nuclear RNA export factor
E 102256432 NXF1; nuclear RNA export factor 1 K14284 NXF; nuclear RNA export factor
E 102259387 nuclear RNA export factor 2 K14284 NXF; nuclear RNA export factor
E 102239683 nuclear RNA export factor 2 K14284 NXF; nuclear RNA export factor
E 102263795 nuclear RNA export factor 2-like K14284 NXF; nuclear RNA export factor
E 102240824 NXT2; nuclear transport factor 2 like export factor 2 K14285 NXT1_2; NTF2-related export protein 1/2
E 102240474 NXT1; nuclear transport factor 2 like export factor 1 K14285 NXT1_2; NTF2-related export protein 1/2
D Ran-mediated transport factors
E 102239412 RAN; RAN, member RAS oncogene family K07936 RAN; GTP-binding nuclear protein Ran
E 102262340 ANP32A; acidic nuclear phosphoprotein 32 family member A K18646 ANP32A_C_D; acidic leucine-rich nuclear phosphoprotein 32 family member A/C/D
E 102254993 ANP32B; acidic nuclear phosphoprotein 32 family member B K18647 ANP32B; acidic leucine-rich nuclear phosphoprotein 32 family member B
E 102240486 TNFSF13; tumor necrosis factor superfamily member 13 K05475 TNFSF13; tumor necrosis factor ligand superfamily member 13
E 102249146 ELAVL1; ELAV like RNA binding protein 1 K13088 ELAVL1; ELAV-like protein 1
E 102238690 ELAVL2; ELAV like RNA binding protein 2 K13208 ELAVL2_3_4; ELAV like protein 2/3/4
E 102258924 ELAVL4; ELAV like RNA binding protein 4 K13208 ELAVL2_3_4; ELAV like protein 2/3/4
E 102239151 ELAVL3; ELAV like RNA binding protein 3 K13208 ELAVL2_3_4; ELAV like protein 2/3/4
E 102261469 FAF2; Fas associated factor family member 2 K18726 FAF2; FAS-associated factor 2
E 102250205 VCP; valosin containing protein K13525 VCP; transitional endoplasmic reticulum ATPase
E 102239505 VCPKMT; valosin containing protein lysine methyltransferase K21806 VCPKMT; protein N-lysine methyltransferase METTL21D [EC:2.1.1.-]
E 102241604 TNPO2; transportin 2 K18727 TNPO2; transportin-2
E 102258313 XPO1; exportin 1 K14290 XPO1; exportin-1
E 102260598 XPO7; exportin 7 K18460 XPO7; exportin-7
E 102261923 RANBP17; RAN binding protein 17 K24115 RANBP17; Ran-binding protein 17
E 102260019 RANGAP1; Ran GTPase activating protein 1 K14319 RANGAP1; Ran GTPase-activating protein 1
E 102245073 TAF15; TATA-box binding protein associated factor 15 K14651 TAF15; transcription initiation factor TFIID subunit 15
D eIF4F and regulatory proteins
E 102242528 EIF4E2; eukaryotic translation initiation factor 4E family member 2 K03259 EIF4E; translation initiation factor 4E
E 102239076 EIF4E1B; eukaryotic translation initiation factor 4E family member 1B K03259 EIF4E; translation initiation factor 4E
E 102256842 EIF4E; eukaryotic translation initiation factor 4E K03259 EIF4E; translation initiation factor 4E
E 102258517 eukaryotic initiation factor 4A-I-like K03257 EIF4A; translation initiation factor 4A
E 102245343 EIF4A2; eukaryotic translation initiation factor 4A2 K03257 EIF4A; translation initiation factor 4A
E 102241699 EIF4A1; eukaryotic translation initiation factor 4A1 K03257 EIF4A; translation initiation factor 4A
E 102245259 eukaryotic initiation factor 4A-I K03257 EIF4A; translation initiation factor 4A
E 102243195 EIF4G1; eukaryotic translation initiation factor 4 gamma 1 K03260 EIF4G; translation initiation factor 4G
E 102258732 EIF4G2; eukaryotic translation initiation factor 4 gamma 2 K03260 EIF4G; translation initiation factor 4G
E 102260058 EIF4G3; eukaryotic translation initiation factor 4 gamma 3 K03260 EIF4G; translation initiation factor 4G
E 102263110 EIF4B; eukaryotic translation initiation factor 4B K03258 EIF4B; translation initiation factor 4B
E 102247110 EIF4H; eukaryotic translation initiation factor 4H K24086 EIF4H; translation initiation factor 4H
E 102250463 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1 K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
E 102247719 EIF4EBP2; eukaryotic translation initiation factor 4E binding protein 2 K18644 EIF4EBP2; eukaryotic translation initiation factor 4E binding protein 2
E 102243441 eukaryotic translation initiation factor 4E-binding protein 2 K18644 EIF4EBP2; eukaryotic translation initiation factor 4E binding protein 2
E 102245082 EIF4EBP3; eukaryotic translation initiation factor 4E binding protein 3 K18645 EIF4EBP3; eukaryotic translation initiation factor 4E binding protein 3
E 102240932 EIF4ENIF1; eukaryotic translation initiation factor 4E nuclear import factor 1 K18728 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter
E 102238870 ANGEL2; angel homolog 2 K18729 ANGEL; protein angel
E 102257356 ANGEL1; angel homolog 1 K18729 ANGEL; protein angel
E 102243313 FXR2; FMR1 autosomal homolog 2 K15516 FMR; fragile X mental retardation protein
E 102247461 FMR1; fragile X mental retardation 1 K15516 FMR; fragile X mental retardation protein
E 102247604 FXR1; FMR1 autosomal homolog 1 K15516 FMR; fragile X mental retardation protein
E 102243192 cytoplasmic FMR1-interacting protein 1 K05749 CYFIP; cytoplasmic FMR1 interacting protein
E 102245924 CYFIP2; cytoplasmic FMR1 interacting protein 2 K05749 CYFIP; cytoplasmic FMR1 interacting protein
E 102246551 GEMIN5; gem nuclear organelle associated protein 5 K13133 GEMIN5; gem associated protein 5
E 102242145 TACC3; transforming acidic coiled-coil containing protein 3 K14283 TACC3; transforming acidic coiled-coil-containing protein 3
E 102251454 CPEB1; cytoplasmic polyadenylation element binding protein 1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 102246573 cytoplasmic polyadenylation element-binding protein 4 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 102244209 CPEB3; cytoplasmic polyadenylation element binding protein 3 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 102247011 CPEB4; cytoplasmic polyadenylation element binding protein 4 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 102254039 CPEB2; cytoplasmic polyadenylation element binding protein 2 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 102260761 DDX3X; DEAD-box helicase 3, X-linked K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]
E 102260935 ATP-dependent RNA helicase DDX3X K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]
E 102260502 ATP-dependent RNA helicase DDX3X K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]
E 102242222 GIGYF2; GRB10 interacting GYF protein 2 K18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein
E 102258074 GIGYF1; GRB10 interacting GYF protein 1 K18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein
E 102243430 polyadenylate-binding protein 1-like 2 K13126 PABPC; polyadenylate-binding protein
E 102242822 PABPC5; poly(A) binding protein cytoplasmic 5 K13126 PABPC; polyadenylate-binding protein
E 102251716 PABPC4; poly(A) binding protein cytoplasmic 4 K13126 PABPC; polyadenylate-binding protein
E 102254736 PABPC1; poly(A) binding protein cytoplasmic 1 K13126 PABPC; polyadenylate-binding protein
E 102261382 PABPC1L; poly(A) binding protein cytoplasmic 1 like K13126 PABPC; polyadenylate-binding protein
E 102251163 PABPC4L; poly(A) binding protein cytoplasmic 4 like K13126 PABPC; polyadenylate-binding protein
E 102247709 polyadenylate-binding protein 1 K13126 PABPC; polyadenylate-binding protein
E 102249240 PAIP1; poly(A) binding protein interacting protein 1 K14322 PAIP1; polyadenylate-binding protein-interacting protein 1
E 102256874 polyadenylate-binding protein-interacting protein 1 K14322 PAIP1; polyadenylate-binding protein-interacting protein 1
E 102263865 PAIP2; poly(A) binding protein interacting protein 2 K27470 PAIP2; polyadenylate-binding protein-interacting protein 2
E 102247455 PAIP2B; poly(A) binding protein interacting protein 2B K27470 PAIP2; polyadenylate-binding protein-interacting protein 2
E 102262440 SKIV2L; Ski2 like RNA helicase K12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6]
E 102244467 DEAF1; DEAF1, transcription factor K23041 DEAF1; deformed epidermal autoregulatory factor 1
E 102257097 malignant T-cell-amplified sequence 1 K07575 MCTS; malignant T-cell-amplified sequence
E 102246584 malignant T-cell-amplified sequence 1 K07575 MCTS; malignant T-cell-amplified sequence
E 102248355 density-regulated protein-like K24272 DENR; density-regulated protein
D APOBEC1-ACF complex
E 102246260 APOBEC1; apolipoprotein B mRNA editing enzyme catalytic subunit 1 K16932 APOBEC1; C->U-editing enzyme APOBEC1 [EC:3.5.4.36]
E 102255318 A1CF; APOBEC1 complementation factor K24978 A1CF; APOBEC1 complementation factor
D Other transport factors
E 102253835 partner of Y14 and mago K14294 WIBG; partner of Y14 and mago
E 102253527 partner of Y14 and mago-like K14294 WIBG; partner of Y14 and mago
E 102243553 HNRNPA1; heterogeneous nuclear ribonucleoprotein A1 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 102246353 heterogeneous nuclear ribonucleoprotein A1 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 102258065 HNRNPA3; heterogeneous nuclear ribonucleoprotein A3 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 102249456 heterogeneous nuclear ribonucleoprotein A1-like K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 102239064 heterogeneous nuclear ribonucleoprotein A1-like K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 106728225 heterogeneous nuclear ribonucleoprotein A1-like K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 102263460 heterogeneous nuclear ribonucleoprotein A3-like K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 102243453 DAZAP1; DAZ associated protein 1 K14411 MSI; RNA-binding protein Musashi
E 102242368 MSI2; musashi RNA binding protein 2 K14411 MSI; RNA-binding protein Musashi
E 102241312 MSI1; musashi RNA binding protein 1 K14411 MSI; RNA-binding protein Musashi
E 102251855 HBS1L; HBS1 like translational GTPase K14416 HBS1; elongation factor 1 alpha-like protein
E 102247465 PELO; pelota homolog (Drosophila) K06965 PELO; protein pelota
E 102245535 polyadenylate-binding protein 2 K14396 PABPN1; polyadenylate-binding protein 2
E 102251980 PABPN1; polyadenylate-binding protein 2 K14396 PABPN1; polyadenylate-binding protein 2
E 102251681 DDX19B; DEAD-box helicase 19B K18655 DDX19; ATP-dependent RNA helicase DDX19/DBP5 [EC:5.6.2.7]
E 102252170 DDX19A; ATP-dependent RNA helicase DDX19A K18655 DDX19; ATP-dependent RNA helicase DDX19/DBP5 [EC:5.6.2.7]
E 102255727 ATP-dependent RNA helicase DDX19A K18655 DDX19; ATP-dependent RNA helicase DDX19/DBP5 [EC:5.6.2.7]
E 102253591 DDX25; DEAD-box helicase 25 K18656 DDX25; ATP-dependent RNA helicase DDX25 [EC:5.6.2.7]
E 102254282 XAB2; XPA binding protein 2 K12867 SYF1; pre-mRNA-splicing factor SYF1
E 102253187 pre-mRNA-splicing factor SYF1-like K12867 SYF1; pre-mRNA-splicing factor SYF1
E 102251537 SARNP; SAP domain containing ribonucleoprotein K18732 SARNP; SAP domain-containing ribonucleoprotein
E 102249752 RCC1; regulator of chromosome condensation 1 K11493 RCC1; regulator of chromosome condensation
E 102249638 LARP6; La ribonucleoprotein domain family member 6 K18733 LARP6; la-related protein 6
E 102238734 PURA; purine rich element binding protein A K21772 PURA; transcriptional activator protein Pur-alpha
E 106724176 PURB; purine rich element binding protein B K21799 PURB; transcriptional activator protein Pur-beta
E 102261044 POLDIP3; DNA polymerase delta interacting protein 3 K22414 POLDIP3; polymerase delta-interacting protein 3
E 102260360 ZC3H11A; zinc finger CCCH-type containing 11A K22415 ZC3H11; zinc finger CCCH domain-containing protein 11
E 102251368 LENG8; leukocyte receptor cluster member 8 K23802 LENG8; SAC3 family protein LENG8/THP3
E 102250588 leukocyte receptor cluster member 8 K23802 LENG8; SAC3 family protein LENG8/THP3
E 102244076 PATL2; PAT1 homolog 2 K24823 PATL2; protein PAT1 homolog 2
C Surveillance factors
D Surveillance complex
E 102259562 ETF1; eukaryotic translation termination factor 1 K03265 ETF1; peptide chain release factor subunit 1
E 102257473 GSPT2; G1 to S phase transition 2 K03267 ERF3; peptide chain release factor subunit 3
E 102264140 GSPT1; G1 to S phase transition 1 K03267 ERF3; peptide chain release factor subunit 3
E 102249803 eukaryotic peptide chain release factor GTP-binding subunit ERF3A-like K03267 ERF3; peptide chain release factor subunit 3
E 102256312 UPF1; UPF1, RNA helicase and ATPase K14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3]
E 102255117 UPF2; UPF2 regulator of nonsense transcripts homolog (yeast) K14327 UPF2; regulator of nonsense transcripts 2
E 102260941 UPF3A; UPF3 regulator of nonsense transcripts homolog A (yeast) K14328 UPF3; regulator of nonsense transcripts 3
E 102252944 UPF3B; UPF3 regulator of nonsense transcripts homolog B (yeast) K14328 UPF3; regulator of nonsense transcripts 3
D Protein phosphatase 2A
E 102246010 PPP2CA; protein phosphatase 2 catalytic subunit alpha K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
E 102255371 PPP2CB; protein phosphatase 2 catalytic subunit beta K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
E 102262643 PPP2R1A; protein phosphatase 2 scaffold subunit Aalpha K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
E 102254517 PPP2R1B; protein phosphatase 2 scaffold subunit Abeta K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
E 102243537 PPP2R2C; protein phosphatase 2 regulatory subunit Bgamma K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
E 102240425 PPP2R2B; protein phosphatase 2 regulatory subunit Bbeta K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
E 102238990 PPP2R2A; protein phosphatase 2 regulatory subunit Balpha K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
E 102254637 PPP2R2D; protein phosphatase 2 regulatory subunit Bdelta K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
E 102248512 PPP2R3C; protein phosphatase 2 regulatory subunit B''gamma K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
E 106725200 serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta-like K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
E 102240816 PPP2R3A; protein phosphatase 2 regulatory subunit B''alpha K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
E 102241218 PPP2R5A; protein phosphatase 2 regulatory subunit B'alpha K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
E 102242374 PPP2R5E; protein phosphatase 2 regulatory subunit B'epsilon K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
E 102239026 PPP2R5C; protein phosphatase 2 regulatory subunit B'gamma K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
E 102249194 PPP2R5D; protein phosphatase 2 regulatory subunit B'delta K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
E 102244211 PPP2R5B; protein phosphatase 2 regulatory subunit B'beta K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
D Other surveillance factors
E 102249244 SMG1; SMG1, nonsense mediated mRNA decay associated PI3K related kinase K08873 SMG1; serine/threonine-protein kinase SMG1 [EC:2.7.11.1]
E 102240128 SMG5; SMG5, nonsense mediated mRNA decay factor K11125 SMG5; protein SMG5
E 102247118 SMG6; SMG6, nonsense mediated mRNA decay factor K11124 SMG6; protein SMG6 [EC:3.1.-.-]
E 102253157 SMG7; SMG7, nonsense mediated mRNA decay factor K14409 SMG7; protein SMG7
E 102245655 SMG8; SMG8, nonsense mediated mRNA decay factor K18734 SMG8; protein SMG8
E 102261959 SMG9; SMG9, nonsense mediated mRNA decay factor K18735 SMG9; protein SMG9
E 102242222 GIGYF2; GRB10 interacting GYF protein 2 K18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein
E 102258074 GIGYF1; GRB10 interacting GYF protein 1 K18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein
E 102239789 SECISBP2; SECIS binding protein 2 K19539 SECISBP2; selenocysteine insertion sequence-binding protein 2
E 102263186 SECISBP2L; SECIS binding protein 2 like K19539 SECISBP2; selenocysteine insertion sequence-binding protein 2
E 102248269 DHX34; DExH-box helicase 34 K20101 DHX34; ATP-dependent RNA helicase DHX34 [EC:5.6.2.6]
E 102249404 GTPBP1; GTP binding protein 1 K24887 GTPBP1; GTP-binding protein 1
C Factors involved in mRNA localization
D Cargo complex
E 102250557 PUM3; pumilio RNA binding family member 3 K14844 PUF6; pumilio homology domain family member 6
E 102254879 MYO5B; myosin VB K10357 MYO5; myosin V
E 102242127 MYO5A; myosin VA K10357 MYO5; myosin V
E 102242423 MYO5C; myosin VC K10357 MYO5; myosin V
E 102251875 BICD2; BICD cargo adaptor 2 K18739 BICD; protein bicaudal D
E 102259490 BICD1; BICD cargo adaptor 1 K18739 BICD; protein bicaudal D
E 102258869 EXD1; exonuclease 3'-5' domain containing 1 K18740 EXD1; exonuclease 3'-5' domain-containing protein 1
D Factors that have mRNA localization signals
E 102263592 ACTG1; actin gamma 1 K05692 ACTB_G1; actin beta/gamma 1
E 102251030 actin, cytoplasmic 1 K05692 ACTB_G1; actin beta/gamma 1
E 102256245 ACTB; actin beta K05692 ACTB_G1; actin beta/gamma 1
E 102244283 MBP; myelin basic protein K17269 MBP; myelin basic protein
E 102242680 VIM; vimentin K07606 VIM; vimentin
E 102261648 metallothionein-2A K14739 MT1_2; metallothionein 1/2
E 102245932 metallothionein-2B-like K14739 MT1_2; metallothionein 1/2
E 102251925 metallothionein-2-like K14739 MT1_2; metallothionein 1/2
E 102250329 metallothionein-1E K14739 MT1_2; metallothionein 1/2
E 102257498 MYC; v-myc avian myelocytomatosis viral oncogene homolog K04377 MYC; Myc proto-oncogene protein
E 102249545 GDF1; growth differentiation factor 1 K05495 GDF1; growth differentiation factor 1
E 102255858 TBX6; T-box 6 K10180 TBX6; T-box protein 6
D Trans-acting binding proteins
E 102241506 ZBP1; Z-DNA binding protein 1 K12965 ZBP1; Z-DNA binding protein 1
E 102256507 FUBP1; far upstream element binding protein 1 K13210 FUBP; far upstream element-binding protein
E 102257290 FUBP3; far upstream element binding protein 3 K13210 FUBP; far upstream element-binding protein
E 102257387 KHSRP; KH-type splicing regulatory protein K13210 FUBP; far upstream element-binding protein
E 102264216 elongation factor 1-alpha 1-like K03231 EEF1A; elongation factor 1-alpha
E 102246009 EEF1A2; eukaryotic translation elongation factor 1 alpha 2 K03231 EEF1A; elongation factor 1-alpha
E 102240077 EEF1A1; eukaryotic translation elongation factor 1 alpha 1 K03231 EEF1A; elongation factor 1-alpha
E 102247638 elongation factor 1-alpha 1-like K03231 EEF1A; elongation factor 1-alpha
E 102259604 elongation factor 1-alpha 1-like K03231 EEF1A; elongation factor 1-alpha
E 102252239 EEF1G; eukaryotic translation elongation factor 1 gamma K03233 EEF1G; elongation factor 1-gamma
E 102263405 heterogeneous nuclear ribonucleoproteins A2/B1 K13158 HNRNPA2B1; heterogeneous nuclear ribonucleoprotein A2/B1
E 102241247 heterogeneous nuclear ribonucleoproteins A2/B1 K13158 HNRNPA2B1; heterogeneous nuclear ribonucleoprotein A2/B1
E 102247146 HNRNPA2B1; heterogeneous nuclear ribonucleoprotein A2/B1 K13158 HNRNPA2B1; heterogeneous nuclear ribonucleoprotein A2/B1
E 102240230 HAX1; HCLS1 associated protein X-1 K16220 HAX1; HCLS1-associated protein X-1
E 102252086 AGFG1; ArfGAP with FG repeats 1 K15044 AGFG1; Arf-GAP domain and FG repeats-containing protein 1
E 102240120 STAU1; staufen double-stranded RNA binding protein 1 K17597 STAU; double-stranded RNA-binding protein Staufen
E 102243173 STAU2; staufen double-stranded RNA binding protein 2 K17597 STAU; double-stranded RNA-binding protein Staufen
E 102239843 IGF2BP3; insulin like growth factor 2 mRNA binding protein 3 K13197 IGF2BP3; insulin-like growth factor 2 mRNA-binding protein 3
E 102261188 PTBP1; polypyrimidine tract binding protein 1 K13218 PTBP1; polypyrimidine tract-binding protein 1
E 102260576 polypyrimidine tract-binding protein 1-like K13218 PTBP1; polypyrimidine tract-binding protein 1
E 102251454 CPEB1; cytoplasmic polyadenylation element binding protein 1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 102246573 cytoplasmic polyadenylation element-binding protein 4 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 102244209 CPEB3; cytoplasmic polyadenylation element binding protein 3 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 102247011 CPEB4; cytoplasmic polyadenylation element binding protein 4 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 102254039 CPEB2; cytoplasmic polyadenylation element binding protein 2 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
D Other mRNA localization factors
E 102243313 FXR2; FMR1 autosomal homolog 2 K15516 FMR; fragile X mental retardation protein
E 102247461 FMR1; fragile X mental retardation 1 K15516 FMR; fragile X mental retardation protein
E 102247604 FXR1; FMR1 autosomal homolog 1 K15516 FMR; fragile X mental retardation protein
E 102243192 cytoplasmic FMR1-interacting protein 1 K05749 CYFIP; cytoplasmic FMR1 interacting protein
E 102245924 CYFIP2; cytoplasmic FMR1 interacting protein 2 K05749 CYFIP; cytoplasmic FMR1 interacting protein
E 102253290 PCBP2; poly(rC) binding protein 2 K13162 PCBP2; poly(rC)-binding protein 2
E 102246181 PCBP3; poly(rC) binding protein 3 K21444 PCBP3_4; poly(rC)-binding protein 3/4
E 102256458 PCBP4; poly(rC) binding protein 4 K21444 PCBP3_4; poly(rC)-binding protein 3/4
E 102247730 CAPRIN1; cell cycle associated protein 1 K18743 CAPRIN1; caprin-1
E 102256081 CAPRIN2; caprin family member 2 K18744 CAPRIN2; caprin-2
E 102239196 YBX1; Y-box binding protein 1 K09276 YBX1; Y-box-binding protein 1
E 102253778 nuclease-sensitive element-binding protein 1 K09276 YBX1; Y-box-binding protein 1
C mRNA cycle factors
D Common to processing body (P body) and stress granule
E 102249234 XRN1; 5'-3' exoribonuclease 1 K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]
E 102263404 AGO4; argonaute 4, RISC catalytic component K11593 ELF2C; eukaryotic translation initiation factor 2C
E 102261195 AGO3; argonaute 3, RISC catalytic component K11593 ELF2C; eukaryotic translation initiation factor 2C
E 102260706 AGO1; argonaute 1, RISC catalytic component K11593 ELF2C; eukaryotic translation initiation factor 2C
E 102250474 AGO2; protein argonaute-2 K11593 ELF2C; eukaryotic translation initiation factor 2C
E 102242528 EIF4E2; eukaryotic translation initiation factor 4E family member 2 K03259 EIF4E; translation initiation factor 4E
E 102239076 EIF4E1B; eukaryotic translation initiation factor 4E family member 1B K03259 EIF4E; translation initiation factor 4E
E 102256842 EIF4E; eukaryotic translation initiation factor 4E K03259 EIF4E; translation initiation factor 4E
E 102256312 UPF1; UPF1, RNA helicase and ATPase K14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3]
E 102260761 DDX3X; DEAD-box helicase 3, X-linked K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]
E 102260935 ATP-dependent RNA helicase DDX3X K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]
E 102260502 ATP-dependent RNA helicase DDX3X K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]
E 102261407 DDX6; DEAD-box helicase 6 K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7]
E 102252592 MEX3C; mex-3 RNA binding family member C K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
E 102262178 MEX3A; mex-3 RNA binding family member A K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
E 102254535 FASTK; Fas activated serine/threonine kinase K08290 FASTK; Fas-activated serine/threonine kinase [EC:2.7.11.8]
E 102255478 LSM14B; LSM family member 14B K18749 LSM14; protein LSM14
E 102258504 LSM14A; LSM14A, mRNA processing body assembly factor K18749 LSM14; protein LSM14
E 102252317 PCBP1; poly(rC) binding protein 1 K12889 PCBP1; poly(rC)-binding protein 1
E 102253290 PCBP2; poly(rC) binding protein 2 K13162 PCBP2; poly(rC)-binding protein 2
E 102239196 YBX1; Y-box binding protein 1 K09276 YBX1; Y-box-binding protein 1
E 102253778 nuclease-sensitive element-binding protein 1 K09276 YBX1; Y-box-binding protein 1
E 102263582 WTIP; Wilms tumor 1 interacting protein K16682 AJUBA; LIM domain-containing protein
E 102250396 LIMD1; LIM domains containing 1 K16682 AJUBA; LIM domain-containing protein
E 102257887 LIM domain-containing protein ajuba K16682 AJUBA; LIM domain-containing protein
E 102247682 LIM domain-containing protein 1 K16682 AJUBA; LIM domain-containing protein
E 102246260 APOBEC1; apolipoprotein B mRNA editing enzyme catalytic subunit 1 K16932 APOBEC1; C->U-editing enzyme APOBEC1 [EC:3.5.4.36]
E 102240642 DNA dC->dU-editing enzyme APOBEC-3G-like K18750 APOBEC3; C->U-editing enzyme APOBEC3 [EC:3.5.4.-]
E 102253539 uncharacterized LOC102253539 K18750 APOBEC3; C->U-editing enzyme APOBEC3 [EC:3.5.4.-]
E 102258209 DNA dC->dU-editing enzyme APOBEC-3G-like K18750 APOBEC3; C->U-editing enzyme APOBEC3 [EC:3.5.4.-]
E 102260004 DNA dC->dU-editing enzyme APOBEC-3D-like K18750 APOBEC3; C->U-editing enzyme APOBEC3 [EC:3.5.4.-]
E 102260414 DNA dC->dU-editing enzyme APOBEC-3G-like K18750 APOBEC3; C->U-editing enzyme APOBEC3 [EC:3.5.4.-]
E 106728123 DNA dC->dU-editing enzyme APOBEC-3G-like K18750 APOBEC3; C->U-editing enzyme APOBEC3 [EC:3.5.4.-]
E 102254933 MOV10; Mov10 RISC complex RNA helicase K18422 MOV10; helicase MOV-10 [EC:5.6.2.5]
E 102253521 PNRC2; proline rich nuclear receptor coactivator 2 K18751 PNRC2; proline-rich nuclear receptor coactivator 2
E 102252932 TNPO1; transportin 1 K18752 TNPO1; transportin-1
E 102249244 SMG1; SMG1, nonsense mediated mRNA decay associated PI3K related kinase K08873 SMG1; serine/threonine-protein kinase SMG1 [EC:2.7.11.1]
E 102240128 SMG5; SMG5, nonsense mediated mRNA decay factor K11125 SMG5; protein SMG5
E 102247118 SMG6; SMG6, nonsense mediated mRNA decay factor K11124 SMG6; protein SMG6 [EC:3.1.-.-]
E 102253157 SMG7; SMG7, nonsense mediated mRNA decay factor K14409 SMG7; protein SMG7
E 102259308 ZFP36; ZFP36 ring finger protein K15308 TTP; tristetraprolin
E 102256184 ZFP36L2; ZFP36 ring finger protein like 2 K18753 ZFP36L; butyrate response factor
E 102261715 ZFP36L1; ZFP36 ring finger protein like 1 K18753 ZFP36L; butyrate response factor
E 102239320 LIN28A; lin-28 homolog A K18754 LIN28; protein lin-28
E 102262050 LIN28B; lin-28 homolog B K18754 LIN28; protein lin-28
E 102250928 HTT; huntingtin K04533 HD; huntingtin
E 102263711 IPO8; importin 8 K18755 IPO8; importin-8
E 102254677 BICC1; BicC family RNA binding protein 1 K18756 BICC1; protein bicaudal C
E 102243553 HNRNPA1; heterogeneous nuclear ribonucleoprotein A1 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 102246353 heterogeneous nuclear ribonucleoprotein A1 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 102258065 HNRNPA3; heterogeneous nuclear ribonucleoprotein A3 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 102249456 heterogeneous nuclear ribonucleoprotein A1-like K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 102239064 heterogeneous nuclear ribonucleoprotein A1-like K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 106728225 heterogeneous nuclear ribonucleoprotein A1-like K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 102263460 heterogeneous nuclear ribonucleoprotein A3-like K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 102244919 PRKACB; protein kinase cAMP-activated catalytic subunit beta K04345 PKA; protein kinase A [EC:2.7.11.11]
E 102252927 PRKACA; protein kinase cAMP-activated catalytic subunit alpha K04345 PKA; protein kinase A [EC:2.7.11.11]
E 102244832 LARP1; La ribonucleoprotein domain family member 1 K18757 LARP1; la-related protein 1
E 102255333 LARP1B; La ribonucleoprotein domain family member 1B K18757 LARP1; la-related protein 1
E 102257957 ATXN2; ataxin 2 K23625 ATXN2_2L; ataxin 2/2L
E 102260634 ATXN2L; ataxin 2 like K23625 ATXN2_2L; ataxin 2/2L
D P-body specific factors
E 102255386 DCP2; decapping mRNA 2 K12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]
E 102260995 DCP1A; decapping mRNA 1A K12610 DCP1A; mRNA-decapping enzyme 1A [EC:3.-.-.-]
E 102253988 DCP1B; decapping mRNA 1B K12611 DCP1B; mRNA-decapping enzyme 1B [EC:3.-.-.-]
E 102255949 LSM2; LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated K12621 LSM2; U6 snRNA-associated Sm-like protein LSm2
E 102246960 LSM3; LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3
E 102262722 LSM4; LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated K12623 LSM4; U6 snRNA-associated Sm-like protein LSm4
E 102261004 U6 snRNA-associated Sm-like protein LSm4 K12623 LSM4; U6 snRNA-associated Sm-like protein LSm4
E 102258795 LSM5; LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated K12624 LSM5; U6 snRNA-associated Sm-like protein LSm5
E 102238756 LSM6; LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6
E 102257586 U6 snRNA-associated Sm-like protein LSm6 K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6
E 102250366 LSM7; LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7
E 102254425 U6 snRNA-associated Sm-like protein LSm7 K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7
E 102258246 LSM8; LSM8 homolog, U6 small nuclear RNA associated K12627 LSM8; U6 snRNA-associated Sm-like protein LSm8
E 102247212 KLC4; kinesin light chain 4 K10407 KLC; kinesin light chain
E 102249559 KLC1; kinesin light chain 1 K10407 KLC; kinesin light chain
E 102262355 KLC3; kinesin light chain 3 K10407 KLC; kinesin light chain
E 102262676 KLC2; kinesin light chain 2 K10407 KLC; kinesin light chain
E 102254879 MYO5B; myosin VB K10357 MYO5; myosin V
E 102242127 MYO5A; myosin VA K10357 MYO5; myosin V
E 102242423 MYO5C; myosin VC K10357 MYO5; myosin V
E 102257777 tubulin alpha-8 chain-like K07374 TUBA; tubulin alpha
E 102249754 tubulin alpha-3 chain-like K07374 TUBA; tubulin alpha
E 102254409 TUBAL3; tubulin alpha like 3 K07374 TUBA; tubulin alpha
E 102255814 tubulin alpha-1C chain K07374 TUBA; tubulin alpha
E 102243100 TUBA1A; tubulin alpha-1A chain K07374 TUBA; tubulin alpha
E 102242793 tubulin alpha-1A chain K07374 TUBA; tubulin alpha
E 102262928 tubulin alpha chain K07374 TUBA; tubulin alpha
E 102257275 TUBA8; tubulin alpha 8 K07374 TUBA; tubulin alpha
E 102262047 tubulin alpha-1D chain K07374 TUBA; tubulin alpha
E 102261453 TUBA4A; tubulin alpha 4a K07374 TUBA; tubulin alpha
E 102257200 tubulin alpha-1B chain K07374 TUBA; tubulin alpha
E 102250856 tubulin alpha-3 chain K07374 TUBA; tubulin alpha
E 102251454 CPEB1; cytoplasmic polyadenylation element binding protein 1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 102246573 cytoplasmic polyadenylation element-binding protein 4 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 102244209 CPEB3; cytoplasmic polyadenylation element binding protein 3 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 102247011 CPEB4; cytoplasmic polyadenylation element binding protein 4 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 102254039 CPEB2; cytoplasmic polyadenylation element binding protein 2 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 102246551 GEMIN5; gem nuclear organelle associated protein 5 K13133 GEMIN5; gem associated protein 5
E 102242145 TACC3; transforming acidic coiled-coil containing protein 3 K14283 TACC3; transforming acidic coiled-coil-containing protein 3
E 102239781 TNRC6A; trinucleotide repeat containing 6A K18412 TNRC6; trinucleotide repeat-containing gene 6 protein
E 102263014 TNRC6B; trinucleotide repeat containing 6B K18412 TNRC6; trinucleotide repeat-containing gene 6 protein
E 102254670 TNRC6C; trinucleotide repeat containing 6C K18412 TNRC6; trinucleotide repeat-containing gene 6 protein
E 102260427 CNOT1; CCR4-NOT transcription complex subunit 1 K12604 CNOT1; CCR4-NOT transcription complex subunit 1
E 102253879 CNOT2; CCR4-NOT transcription complex subunit 2 K12605 CNOT2; CCR4-NOT transcription complex subunit 2
E 102258386 CNOT3; CCR4-NOT transcription complex subunit 3 K12580 CNOT3; CCR4-NOT transcription complex subunit 3
E 102249882 CNOT4; CCR4-NOT transcription complex subunit 4 K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]
E 102261756 CNOT6; CCR4-NOT transcription complex subunit 6 K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E 102263967 CNOT6L; CCR4-NOT transcription complex subunit 6 like K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E 102245135 CNOT8; CCR4-NOT transcription complex subunit 8 K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E 102249611 CNOT7; CCR4-NOT transcription complex subunit 7 K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E 102258195 KIAA0355 ortholog K26671 GARRE1; granule associated Rac and RHOG effector protein 1
E 102243611 DIS3L2; DIS3 like 3'-5' exoribonuclease 2 K18758 DIS3L2; DIS3-like exonuclease 2 [EC:3.1.13.-]
E 102239430 PAN2; PAN2 poly(A) specific ribonuclease subunit K12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4]
E 102260545 PAN3; PAN3 poly(A) specific ribonuclease subunit K12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3
E 102263921 TOB1; transducer of ERBB2, 1 K14443 TOB; protein Tob/BTG
E 102259223 TOB2; transducer of ERBB2, 2 K14443 TOB; protein Tob/BTG
E 102245347 BTG1; BTG anti-proliferation factor 1 K14443 TOB; protein Tob/BTG
E 102248369 BTG3; BTG anti-proliferation factor 3 K14443 TOB; protein Tob/BTG
E 102246373 BTG2; BTG anti-proliferation factor 2 K14443 TOB; protein Tob/BTG
E 102238930 BTG4; BTG anti-proliferation factor 4 K14443 TOB; protein Tob/BTG
E 102240932 EIF4ENIF1; eukaryotic translation initiation factor 4E nuclear import factor 1 K18728 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter
E 102240984 PATL1; PAT1 homolog 1, processing body mRNA decay factor K12617 PATL1; DNA topoisomerase 2-associated protein PAT1
E 102262663 EDC3; enhancer of mRNA decapping 3 K12615 EDC3; enhancer of mRNA-decapping protein 3
E 102260346 EDC4; enhancer of mRNA decapping 4 K12616 EDC4; enhancer of mRNA-decapping protein 4
E 102245686 NANOS2; nanos C2HC-type zinc finger 2 K18760 NANOS2; protein nanos 2
E 102251473 NANOS3; nanos C2HC-type zinc finger 3 K18761 NANOS3; protein nanos 3
E 102255117 UPF2; UPF2 regulator of nonsense transcripts homolog (yeast) K14327 UPF2; regulator of nonsense transcripts 2
E 102260941 UPF3A; UPF3 regulator of nonsense transcripts homolog A (yeast) K14328 UPF3; regulator of nonsense transcripts 3
E 102252944 UPF3B; UPF3 regulator of nonsense transcripts homolog B (yeast) K14328 UPF3; regulator of nonsense transcripts 3
E 102239193 TRIM21; tripartite motif containing 21 K10651 TRIM21; tripartite motif-containing protein 21 [EC:2.3.2.27]
E 102241783 TRIM71; tripartite motif containing 71 K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
E 102262423 POLR2G; RNA polymerase II subunit G K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7
E 102242739 EIF2AK2; interferon-induced, double-stranded RNA-activated protein kinase K16195 EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]
E 102249919 ZAR1-like protein K18762 ZAR1; zygote arrest protein 1
E 106723662 ZAR1L; zygote arrest 1-like K18762 ZAR1; zygote arrest protein 1
E 102240609 YTH domain-containing family protein 3 K20102 YTHDF; YTH domain-containing family protein
E 102248162 YTHDF2; YTH N6-methyladenosine RNA binding protein 2 K20102 YTHDF; YTH domain-containing family protein
E 102248717 YTHDF1; YTH N6-methyladenosine RNA binding protein 1 K20102 YTHDF; YTH domain-containing family protein
E 102263437 YTHDF3; YTH N6-methyladenosine RNA binding protein 3 K20102 YTHDF; YTH domain-containing family protein
D Stress granule specific factors
E 102250327 TIA1; TIA1 cytotoxic granule associated RNA binding protein K13201 TIA1; nucleolysin TIA-1/TIAR
E 102260857 TIAL1; TIA1 cytotoxic granule associated RNA binding protein like 1 K13201 TIA1; nucleolysin TIA-1/TIAR
E 102243430 polyadenylate-binding protein 1-like 2 K13126 PABPC; polyadenylate-binding protein
E 102242822 PABPC5; poly(A) binding protein cytoplasmic 5 K13126 PABPC; polyadenylate-binding protein
E 102251716 PABPC4; poly(A) binding protein cytoplasmic 4 K13126 PABPC; polyadenylate-binding protein
E 102254736 PABPC1; poly(A) binding protein cytoplasmic 1 K13126 PABPC; polyadenylate-binding protein
E 102261382 PABPC1L; poly(A) binding protein cytoplasmic 1 like K13126 PABPC; polyadenylate-binding protein
E 102251163 PABPC4L; poly(A) binding protein cytoplasmic 4 like K13126 PABPC; polyadenylate-binding protein
E 102247709 polyadenylate-binding protein 1 K13126 PABPC; polyadenylate-binding protein
E 102240120 STAU1; staufen double-stranded RNA binding protein 1 K17597 STAU; double-stranded RNA-binding protein Staufen
E 102243173 STAU2; staufen double-stranded RNA binding protein 2 K17597 STAU; double-stranded RNA-binding protein Staufen
E 102243313 FXR2; FMR1 autosomal homolog 2 K15516 FMR; fragile X mental retardation protein
E 102247461 FMR1; fragile X mental retardation 1 K15516 FMR; fragile X mental retardation protein
E 102247604 FXR1; FMR1 autosomal homolog 1 K15516 FMR; fragile X mental retardation protein
E 102241506 ZBP1; Z-DNA binding protein 1 K12965 ZBP1; Z-DNA binding protein 1
E 102249146 ELAVL1; ELAV like RNA binding protein 1 K13088 ELAVL1; ELAV-like protein 1
E 102241352 G3BP1; G3BP stress granule assembly factor 1 K17265 G3BP1; Ras GTPase-activating protein-binding protein 1 [EC:5.6.2.5 5.6.2.3]
E 102263036 G3BP2; G3BP stress granule assembly factor 2 K24983 G3BP2; Ras GTPase-activating protein-binding protein 2
E 102264207 EIF2A; eukaryotic translation initiation factor 2A K15026 EIF2A; translation initiation factor 2A
E 102257788 EIF3B; eukaryotic translation initiation factor 3 subunit B K03253 EIF3B; translation initiation factor 3 subunit B
E 102258517 eukaryotic initiation factor 4A-I-like K03257 EIF4A; translation initiation factor 4A
E 102245343 EIF4A2; eukaryotic translation initiation factor 4A2 K03257 EIF4A; translation initiation factor 4A
E 102241699 EIF4A1; eukaryotic translation initiation factor 4A1 K03257 EIF4A; translation initiation factor 4A
E 102245259 eukaryotic initiation factor 4A-I K03257 EIF4A; translation initiation factor 4A
E 102261425 EIF4A3; eukaryotic translation initiation factor 4A3 K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]
E 102263110 EIF4B; eukaryotic translation initiation factor 4B K03258 EIF4B; translation initiation factor 4B
E 102243195 EIF4G1; eukaryotic translation initiation factor 4 gamma 1 K03260 EIF4G; translation initiation factor 4G
E 102258732 EIF4G2; eukaryotic translation initiation factor 4 gamma 2 K03260 EIF4G; translation initiation factor 4G
E 102260058 EIF4G3; eukaryotic translation initiation factor 4 gamma 3 K03260 EIF4G; translation initiation factor 4G
E 102245651 RPS6KA2; ribosomal protein S6 kinase A2 K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E 102263950 RPS6KA1; ribosomal protein S6 kinase A1 K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E 102247755 RPS6KA3; ribosomal protein S6 kinase A3 K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E 102248542 RPS6KA6; ribosomal protein S6 kinase A6 K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E 102242524 RACK1; receptor for activated C kinase 1 K14753 RACK1; guanine nucleotide-binding protein subunit beta-2-like 1 protein
E 102263277 TRAF2; TNF receptor associated factor 2 K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
E 102258513 nuclear RNA export factor 2 K14284 NXF; nuclear RNA export factor
E 102239377 NXF3; nuclear RNA export factor 3 K14284 NXF; nuclear RNA export factor
E 102256432 NXF1; nuclear RNA export factor 1 K14284 NXF; nuclear RNA export factor
E 102259387 nuclear RNA export factor 2 K14284 NXF; nuclear RNA export factor
E 102239683 nuclear RNA export factor 2 K14284 NXF; nuclear RNA export factor
E 102263795 nuclear RNA export factor 2-like K14284 NXF; nuclear RNA export factor
E 102261327 HDAC6; histone deacetylase 6 K11407 HDAC6; histone deacetylase 6 [EC:3.5.1.98]
E 102260724 TDRD3; tudor domain containing 3 K18404 TDRD3; tudor domain-containing protein 3
E 102239266 LARP4B; La ribonucleoprotein domain family member 4B K18763 LARP4; la-related protein 4
E 102254694 LARP4; La ribonucleoprotein domain family member 4 K18763 LARP4; la-related protein 4
B mRNA degradation factors
C 5'-3' decay
D Decapping complex
E 102260995 DCP1A; decapping mRNA 1A K12610 DCP1A; mRNA-decapping enzyme 1A [EC:3.-.-.-]
E 102253988 DCP1B; decapping mRNA 1B K12611 DCP1B; mRNA-decapping enzyme 1B [EC:3.-.-.-]
E 102255386 DCP2; decapping mRNA 2 K12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]
E 102261407 DDX6; DEAD-box helicase 6 K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7]
E 102262663 EDC3; enhancer of mRNA decapping 3 K12615 EDC3; enhancer of mRNA-decapping protein 3
E 102260346 EDC4; enhancer of mRNA decapping 4 K12616 EDC4; enhancer of mRNA-decapping protein 4
E 102240984 PATL1; PAT1 homolog 1, processing body mRNA decay factor K12617 PATL1; DNA topoisomerase 2-associated protein PAT1
D Lsm complex
E 102255949 LSM2; LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated K12621 LSM2; U6 snRNA-associated Sm-like protein LSm2
E 102246960 LSM3; LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3
E 102262722 LSM4; LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated K12623 LSM4; U6 snRNA-associated Sm-like protein LSm4
E 102261004 U6 snRNA-associated Sm-like protein LSm4 K12623 LSM4; U6 snRNA-associated Sm-like protein LSm4
E 102258795 LSM5; LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated K12624 LSM5; U6 snRNA-associated Sm-like protein LSm5
E 102238756 LSM6; LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6
E 102257586 U6 snRNA-associated Sm-like protein LSm6 K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6
E 102250366 LSM7; LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7
E 102254425 U6 snRNA-associated Sm-like protein LSm7 K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7
E 102258246 LSM8; LSM8 homolog, U6 small nuclear RNA associated K12627 LSM8; U6 snRNA-associated Sm-like protein LSm8
D 5' exonucleases
E 102249234 XRN1; 5'-3' exoribonuclease 1 K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]
E 102263305 XRN2; 5'-3' exoribonuclease 2 K12619 XRN2; 5'-3' exoribonuclease 2 [EC:3.1.13.-]
E 102252289 NUDT16; nudix hydrolase 16 K16855 NUDT16; U8 snoRNA-decapping enzyme [EC:3.6.1.62 3.6.1.64]
D Other 5'-3' decay factors
E 102251721 DCPS; decapping enzyme, scavenger K12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]
E 102259255 HELZ; helicase with zinc finger K25168 HELZ; helicase with zinc finger domain [EC:5.6.2.-]
C 3'-5' decay
D Core exosome factors
E 102249716 EXOSC1; exosome component 1 K07573 CSL4; exosome complex component CSL4
E 102255775 EXOSC2; exosome component 2 K03679 RRP4; exosome complex component RRP4
E 102254667 EXOSC3; exosome component 3 K03681 RRP40; exosome complex component RRP40
E 106725898 EXOSC4; exosome component 4 K11600 RRP41; exosome complex component RRP41
E 102240837 EXOSC5; exosome component 5 K12590 RRP46; exosome complex component RRP46
E 102249499 EXOSC7; exosome component 7 K12589 RRP42; exosome complex component RRP42
E 102241781 EXOSC8; exosome complex component RRP43 K12586 RRP43; exosome complex component RRP43
E 102245044 exosome complex component RRP43 K12586 RRP43; exosome complex component RRP43
E 102252284 EXOSC9; exosome component 9 K03678 RRP45; exosome complex component RRP45
D Exosome cofactors
E 102252677 DIS3; DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease K12585 DIS3; exosome complex exonuclease DIS3/RRP44 [EC:3.1.13.-]
E 102256967 DIS3L; DIS3 like exosome 3'-5' exoribonuclease K18681 DIS3L; DIS3-like exonuclease 1 [EC:3.1.13.-]
E 102240459 EXOSC10; exosome component 10 K12591 RRP6; exosome complex exonuclease RRP6 [EC:3.1.13.-]
E 102246314 C1D; C1D nuclear receptor corepressor K12592 C1D; exosome complex protein LRP1
E 102243481 nuclear nucleic acid-binding protein C1D K12592 C1D; exosome complex protein LRP1
E 102241527 nuclear nucleic acid-binding protein C1D K12592 C1D; exosome complex protein LRP1
E 102260285 MPHOSPH6; M-phase phosphoprotein 6 K12593 MPHOSPH6; M-phase phosphoprotein 6, animal type
E 102257669 probable ATP-dependent RNA helicase DDX60 K20103 DDX60; ATP-dependent RNA helicase DDX60 [EC:5.6.2.7]
E 102257980 probable ATP-dependent RNA helicase DDX60 K20103 DDX60; ATP-dependent RNA helicase DDX60 [EC:5.6.2.7]
D TRAMP complex
E 102242396 PAPD7; poly(A) RNA polymerase D7, non-canonical K03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19]
E 102247320 PAPD5; poly(A) RNA polymerase D5, non-canonical K03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19]
E 102256470 ZCCHC7; zinc finger CCHC-type containing 7 K12597 AIR1_2; protein AIR1/2
E 102252808 SKIV2L2; Ski2 like RNA helicase 2 K12598 MTR4; ATP-dependent RNA helicase DOB1 [EC:5.6.2.6]
D Ski complex
E 102262440 SKIV2L; Ski2 like RNA helicase K12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6]
E 102257417 TTC37; tetratricopeptide repeat domain 37 K12600 SKI3; superkiller protein 3
E 102242777 WDR61; WD repeat domain 61 K12602 WDR61; WD repeat-containing protein 61
D Ccr4-NOT complex
E 102261756 CNOT6; CCR4-NOT transcription complex subunit 6 K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E 102263967 CNOT6L; CCR4-NOT transcription complex subunit 6 like K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E 102260427 CNOT1; CCR4-NOT transcription complex subunit 1 K12604 CNOT1; CCR4-NOT transcription complex subunit 1
E 102253879 CNOT2; CCR4-NOT transcription complex subunit 2 K12605 CNOT2; CCR4-NOT transcription complex subunit 2
E 102258386 CNOT3; CCR4-NOT transcription complex subunit 3 K12580 CNOT3; CCR4-NOT transcription complex subunit 3
E 102249882 CNOT4; CCR4-NOT transcription complex subunit 4 K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]
E 102245135 CNOT8; CCR4-NOT transcription complex subunit 8 K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E 102249611 CNOT7; CCR4-NOT transcription complex subunit 7 K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E 102252176 CNOT9; CCR4-NOT transcription complex subunit 9 K12606 RCD1; CCR4-NOT transcription complex subunit 9
E 102262002 CNOT10; CCR4-NOT transcription complex subunit 10 K12607 CNOT10; CCR4-NOT transcription complex subunit 10
D Pan complex
E 102239430 PAN2; PAN2 poly(A) specific ribonuclease subunit K12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4]
E 102260545 PAN3; PAN3 poly(A) specific ribonuclease subunit K12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3
D Other 3'-5' decay factors
E 102243649 PARN; poly(A)-specific ribonuclease K01148 PARN; poly(A)-specific ribonuclease [EC:3.1.13.4]
E 102262108 PNLDC1; PARN like, ribonuclease domain containing 1 K01148 PARN; poly(A)-specific ribonuclease [EC:3.1.13.4]
E 102257831 DHX36; DEAH-box helicase 36 K14442 DHX36; ATP-dependent RNA helicase DHX36 [EC:5.6.2.6]
E 102263921 TOB1; transducer of ERBB2, 1 K14443 TOB; protein Tob/BTG
E 102259223 TOB2; transducer of ERBB2, 2 K14443 TOB; protein Tob/BTG
E 102245347 BTG1; BTG anti-proliferation factor 1 K14443 TOB; protein Tob/BTG
E 102248369 BTG3; BTG anti-proliferation factor 3 K14443 TOB; protein Tob/BTG
E 102246373 BTG2; BTG anti-proliferation factor 2 K14443 TOB; protein Tob/BTG
E 102238930 BTG4; BTG anti-proliferation factor 4 K14443 TOB; protein Tob/BTG
E 106726621 granulocyte-macrophage colony-stimulating factor-like K05427 CSF2; granulocyte-macrophage colony-stimulating factor
E 102242138 CSF2; colony stimulating factor 2 K05427 CSF2; granulocyte-macrophage colony-stimulating factor
E 102260842 NOCT; nocturnin K18764 NOCT; nocturnin [EC:3.1.3.108]
E 102257179 ERI1; exoribonuclease 1 K18416 THEX1; 3'-5' exoribonuclease 1 [EC:3.1.-.-]
E 102241603 ERI2; ERI1 exoribonuclease family member 2 K18417 ERI2; ERI1 exoribonuclease 2 [EC:3.1.-.-]
E 102251721 DCPS; decapping enzyme, scavenger K12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]
E 102241344 PDE12; phosphodiesterase 12 K19612 PDE12; 2',5'-phosphodiesterase [EC:3.1.13.4 3.1.4.-]
E 102246041 IREB2; iron responsive element binding protein 2 K22416 IREB2; iron-responsive element-binding protein 2
E 102259255 HELZ; helicase with zinc finger K25168 HELZ; helicase with zinc finger domain [EC:5.6.2.-]
E 102260979 HELZ2; helicase with zinc finger 2 K25165 HELZ2; 3'-5' exoribonuclease HELZ2 [EC:3.1.13.1 5.6.2.6]
E 102250439 NRDE2; NRDE-2, necessary for RNA interference, domain containing K26109 NRDE2; nuclear exosome regulator NRDE2
E 102239314 SAMD4A; sterile alpha motif domain containing 4A K27396 SMG; protein Smaug
E 102260709 SAMD4B; sterile alpha motif domain containing 4B K27396 SMG; protein Smaug
E 102245280 FOCAD; focadhesin K27498 FOCAD; focadhesin
C Other degradation factors
D RNases
E 102255887 ribonuclease pancreatic K01168 RNASE1_2; pancreatic ribonuclease [EC:4.6.1.18]
E 102258486 ribonuclease pancreatic K01168 RNASE1_2; pancreatic ribonuclease [EC:4.6.1.18]
E 102246159 RNASE2; non-secretory ribonuclease K01168 RNASE1_2; pancreatic ribonuclease [EC:4.6.1.18]
E 102242292 RNASE1; ribonuclease A family member 1, pancreatic K01168 RNASE1_2; pancreatic ribonuclease [EC:4.6.1.18]
E 102254467 ribonuclease pancreatic K01168 RNASE1_2; pancreatic ribonuclease [EC:4.6.1.18]
E 102246040 ribonuclease pancreatic K01168 RNASE1_2; pancreatic ribonuclease [EC:4.6.1.18]
E 102253380 RNASE4; ribonuclease A family member 4 K16632 RNASE4; ribonuclease 4 [EC:3.1.27.-]
E 102257224 ribonuclease 4-like K16632 RNASE4; ribonuclease 4 [EC:3.1.27.-]
E 102243492 ribonuclease 4 K16632 RNASE4; ribonuclease 4 [EC:3.1.27.-]
E 102244300 ribonuclease 4-like K16632 RNASE4; ribonuclease 4 [EC:3.1.27.-]
E 102248960 ribonuclease 4 K16632 RNASE4; ribonuclease 4 [EC:3.1.27.-]
E 102249749 ribonuclease 4 K16632 RNASE4; ribonuclease 4 [EC:3.1.27.-]
E 102254750 ribonuclease 4 K16632 RNASE4; ribonuclease 4 [EC:3.1.27.-]
E 102255358 ribonuclease 4-like K16632 RNASE4; ribonuclease 4 [EC:3.1.27.-]
E 102255964 ribonuclease 4 K16632 RNASE4; ribonuclease 4 [EC:3.1.27.-]
E 102261378 ribonuclease 4 K16632 RNASE4; ribonuclease 4 [EC:3.1.27.-]
E 102238697 RNASE7; ribonuclease 7 K01172 RNASE6_7_8; ribonuclease 6/7/8 [EC:3.1.27.-]
E 102242904 RNASE6; ribonuclease A family member k6 K01172 RNASE6_7_8; ribonuclease 6/7/8 [EC:3.1.27.-]
E 102255664 ribonuclease K3 K01172 RNASE6_7_8; ribonuclease 6/7/8 [EC:3.1.27.-]
E 102252779 RNASE11; ribonuclease A family member 11 (inactive) K16633 RNASE11; ribonuclease 11 [EC:3.1.27.-]
E 102243457 ZC3H12A; zinc finger CCCH-type containing 12A K18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]
E 102248807 ZC3H12C; zinc finger CCCH-type containing 12C K18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]
E 102261608 ZC3H12B; zinc finger CCCH-type containing 12B K18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]
E 102256579 ZC3H12D; zinc finger CCCH-type containing 12D K18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]
#
AProkaryotic type
B Bacterial mRNA degradation factors
C RNA degradosome components
D Ribonucreases
E 102259153 DROSHA; drosha ribonuclease III K03685 rnc; ribonuclease III [EC:3.1.26.3]
E 102252234 REXO2; RNA exonuclease 2 K13288 orn; oligoribonuclease [EC:3.1.-.-]
D Helicases
D Other RNA degradosome components
E 102258349 ENO2; enolase 2 K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
E 102263948 ENO1; enolase 1 K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
E 102240806 ENO3; enolase 3 K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
E 102264180 alpha-enolase-like K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
E 102238659 PNPT1; polyribonucleotide nucleotidyltransferase 1 K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
E 102253839 PFKM; phosphofructokinase, muscle K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
E 102260571 PFKL; phosphofructokinase, liver type K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
E 102259510 PFKP; phosphofructokinase, platelet K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
C Other RNA degradation factors
D Chaperones
E 102259869 HSPA9; heat shock protein family A (Hsp70) member 9 K04043 dnaK; molecular chaperone DnaK
E 102253603 HSPD1; heat shock protein family D (Hsp60) member 1 K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
E 102255440 60 kDa heat shock protein, mitochondrial-like K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D Others
D Bacterial Small RNA Regulators
B Archeal mRNA degradation factors
C Exosome components
D Core exosome
E 102255775 EXOSC2; exosome component 2 K03679 RRP4; exosome complex component RRP4
E 102249716 EXOSC1; exosome component 1 K07573 CSL4; exosome complex component CSL4
D Cofactors
E 106725898 EXOSC4; exosome component 4 K11600 RRP41; exosome complex component RRP41
E 102249499 EXOSC7; exosome component 7 K12589 RRP42; exosome complex component RRP42
D Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: April 25, 2024