+D	GENES	KO
#<h2><a href="/kegg/brite.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a> &nbsp; KEGG Orthology (KO) - Natronobacterium gregoryi </h2>
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A09100 Metabolism
B
B  09101 Carbohydrate metabolism
C    00010 Glycolysis / Gluconeogenesis [PATH:nge00010]
D      Natgr_0459 transcriptional regulator/sugar kinase	K25026 glk; glucokinase [EC:2.7.1.2]
D      Natgr_1014 glucose-6-phosphate isomerase	K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]
D      Natgr_2898 archaeal ADP-dependent phosphofructokinase/glucokinase	K00918 pfkC; ADP-dependent phosphofructokinase/glucokinase [EC:2.7.1.146 2.7.1.147]
D      Natgr_2901 fructose-1,6-bisphosphatase	K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]
D      Natgr_2902 DhnA-type fructose-1,6-bisphosphate aldolase-like enzyme	K11645 fbaB; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D      Natgr_0761 putative phospho-2-dehydro-3-deoxyheptonate aldolase	K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10]
D      Natgr_3595 triosephosphate isomerase	K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
D      Natgr_2895 glyceraldehyde-3-phosphate dehydrogenase, type I	K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D      Natgr_1663 glyceraldehyde-3-phosphate dehydrogenase, type I	K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D      Natgr_1664 glyceraldehyde-3-phosphate dehydrogenase, type II	K00150 gap2; glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) [EC:1.2.1.59]
D      Natgr_1662 3-phosphoglycerate kinase	K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]
D      Natgr_2688 2,3-bisphosphoglycerate-independent phosphoglycerate mutase	K15633 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]
D      Natgr_2561 phosphopyruvate hydratase	K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D      Natgr_0653 pyruvate kinase	K00873 PK; pyruvate kinase [EC:2.7.1.40]
D      Natgr_2899 phosphoenolpyruvate synthase	K01007 pps; pyruvate, water dikinase [EC:2.7.9.2]
D      Natgr_3052 phosphoenolpyruvate synthase	K01007 pps; pyruvate, water dikinase [EC:2.7.9.2]
D      Natgr_1353 pyruvate dehydrogenase E1 component, alpha subunit	K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
D      Natgr_1352 pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase component beta subunit	K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
D      Natgr_1351 pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase component	K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
D      Natgr_1350 dihydrolipoamide dehydrogenase	K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D      Natgr_3239 2-oxoacid:acceptor oxidoreductase, alpha subunit	K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D      Natgr_3238 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate family	K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D      Natgr_3122 2-oxoacid:acceptor oxidoreductase, alpha subunit	K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D      Natgr_3123 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate family	K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D      Natgr_2669 NAD-dependent aldehyde dehydrogenase	K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D      Natgr_2311 NAD-dependent aldehyde dehydrogenase	K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D      Natgr_0530 acetate--CoA ligase	K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D      Natgr_0528 acetate--CoA ligase	K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D      Natgr_1583 acyl-CoA synthetase/AMP-acid ligase	K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D      Natgr_3012 acyl-CoA synthetase/AMP-acid ligase	K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D      Natgr_3230 ADP-forming acetyl coenzyme A synthetase	K24012 acdAB; acetate---CoA ligase (ADP-forming) [EC:6.2.1.13]
D      Natgr_1689 phosphoglucosamine mutase	K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D      Natgr_2938 phosphoenolpyruvate carboxykinase (ATP)	K01610 pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49]
C    00020 Citrate cycle (TCA cycle) [PATH:nge00020]
D      Natgr_3706 2-methylcitrate synthase/citrate synthase II	K01647 CS; citrate synthase [EC:2.3.3.1]
D      Natgr_2365 aconitate hydratase, putative, Aquifex type	K01681 ACO; aconitate hydratase [EC:4.2.1.3]
D      Natgr_3359 aconitate hydratase 1	K01681 ACO; aconitate hydratase [EC:4.2.1.3]
D      Natgr_1115 isocitrate dehydrogenase, NADP-dependent, prokaryotic type	K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]
D      Natgr_1350 dihydrolipoamide dehydrogenase	K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D      Natgr_3122 2-oxoacid:acceptor oxidoreductase, alpha subunit	K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D      Natgr_3123 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate family	K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D      Natgr_3687 succinyl-CoA synthetase, alpha subunit	K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]
D      Natgr_3688 succinyl-CoA synthetase, beta subunit	K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]
D      Natgr_2180 acetyl-CoA hydrolase	K18118 aarC; succinyl-CoA:acetate CoA-transferase [EC:2.8.3.18]
D      Natgr_0478 succinate dehydrogenase/fumarate reductase flavoprotein subunit	K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
D      Natgr_0493 succinate dehydrogenase/fumarate reductase flavoprotein subunit	K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
D      Natgr_0492 succinate dehydrogenase and fumarate reductase iron-sulfur protein	K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
D      Natgr_0490 succinate dehydrogenase, cytochrome b556 subunit	K00241 sdhC; succinate dehydrogenase cytochrome b subunit
D      Natgr_0491 succinate dehydrogenase, hydrophobic anchor subunit	K00242 sdhD; succinate dehydrogenase membrane anchor subunit
D      Natgr_0014 fumarase	K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]
D      Natgr_1710 malate/lactate dehydrogenase	K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D      Natgr_2938 phosphoenolpyruvate carboxykinase (ATP)	K01610 pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49]
D      Natgr_1353 pyruvate dehydrogenase E1 component, alpha subunit	K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
D      Natgr_1352 pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase component beta subunit	K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
D      Natgr_1351 pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase component	K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
D      Natgr_3239 2-oxoacid:acceptor oxidoreductase, alpha subunit	K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D      Natgr_3238 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate family	K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
C    00030 Pentose phosphate pathway [PATH:nge00030]
D      Natgr_1014 glucose-6-phosphate isomerase	K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]
D      Natgr_1320 NAD dependent epimerase/dehydratase family protein	K19243 azf; NAD+ dependent glucose-6-phosphate dehydrogenase [EC:1.1.1.388]
D      Natgr_2304 6-phosphogluconate dehydrogenase, decarboxylating	K00033 PGD; 6-phosphogluconate dehydrogenase [EC:1.1.1.44 1.1.1.343]
D      Natgr_1572 ribose 5-phosphate isomerase	K01807 rpiA; ribose 5-phosphate isomerase A [EC:5.3.1.6]
D      Natgr_1132 deoxyribose-phosphate aldolase	K01619 deoC; deoxyribose-phosphate aldolase [EC:4.1.2.4]
D      Natgr_0366 phosphomannomutase	K22199 ppm; phosphopentomutase [EC:5.4.2.7]
D      Natgr_1689 phosphoglucosamine mutase	K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D      Natgr_1135 sugar kinase, ribokinase	K26208 E2.7.1.239; alpha-D-ribose-1-phosphate 5-kinase (ATP) [EC:2.7.1.239]
D      Natgr_1133 ribose-1,5-bisphosphate isomerase, e2b2 family	K18237 K18237; ribose 1,5-bisphosphate isomerase [EC:5.3.1.29]
D      Natgr_2288 translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family	K18237 K18237; ribose 1,5-bisphosphate isomerase [EC:5.3.1.29]
D      Natgr_1686 ribose-phosphate pyrophosphokinase	K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
D      Natgr_2482 Entner-Doudoroff aldolase	K01625 eda; 2-dehydro-3-deoxyphosphogluconate aldolase / (4S)-4-hydroxy-2-oxoglutarate aldolase [EC:4.1.2.14 4.1.3.42]
D      Natgr_0069 theronine dehydrogenase-like Zn-dependent dehydrogenase	K22969 gdh; glucose 1-dehydrogenase [EC:1.1.1.47]
D      Natgr_0070 enolase superfamily enzyme related to L-alanine-DL-glutamate epimerase	K05308 gnaD; gluconate/galactonate dehydratase [EC:4.2.1.140]
D      Natgr_2179 enolase superfamily enzyme related to L-alanine-DL-glutamate epimerase	K05308 gnaD; gluconate/galactonate dehydratase [EC:4.2.1.140]
D      Natgr_2727 sugar kinase, ribokinase	K00874 kdgK; 2-dehydro-3-deoxygluconokinase [EC:2.7.1.45]
D      Natgr_0016 aldehyde:ferredoxin oxidoreductase	K03738 aor; aldehyde:ferredoxin oxidoreductase [EC:1.2.7.5]
D      Natgr_1073 aldehyde:ferredoxin oxidoreductase	K03738 aor; aldehyde:ferredoxin oxidoreductase [EC:1.2.7.5]
D      Natgr_0412 aldehyde:ferredoxin oxidoreductase	K03738 aor; aldehyde:ferredoxin oxidoreductase [EC:1.2.7.5]
D      Natgr_1265 aldehyde:ferredoxin oxidoreductase	K03738 aor; aldehyde:ferredoxin oxidoreductase [EC:1.2.7.5]
D      Natgr_2925 aldehyde:ferredoxin oxidoreductase	K03738 aor; aldehyde:ferredoxin oxidoreductase [EC:1.2.7.5]
D      Natgr_3276 aldehyde:ferredoxin oxidoreductase	K03738 aor; aldehyde:ferredoxin oxidoreductase [EC:1.2.7.5]
D      Natgr_3160 putative glycerate kinase	K11529 gck; glycerate 2-kinase [EC:2.7.1.165]
D      Natgr_2902 DhnA-type fructose-1,6-bisphosphate aldolase-like enzyme	K11645 fbaB; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D      Natgr_0761 putative phospho-2-dehydro-3-deoxyheptonate aldolase	K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10]
D      Natgr_2901 fructose-1,6-bisphosphatase	K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]
D      Natgr_2898 archaeal ADP-dependent phosphofructokinase/glucokinase	K00918 pfkC; ADP-dependent phosphofructokinase/glucokinase [EC:2.7.1.146 2.7.1.147]
C    00040 Pentose and glucuronate interconversions [PATH:nge00040]
D      Natgr_2229 nucleotide sugar dehydrogenase	K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D      Natgr_2683 hypothetical protein	K03079 ulaE; L-ribulose-5-phosphate 3-epimerase [EC:5.1.3.22]
C    00051 Fructose and mannose metabolism [PATH:nge00051]
D      Natgr_1689 phosphoglucosamine mutase	K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D      Natgr_2901 fructose-1,6-bisphosphatase	K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]
D      Natgr_2902 DhnA-type fructose-1,6-bisphosphate aldolase-like enzyme	K11645 fbaB; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D      Natgr_0761 putative phospho-2-dehydro-3-deoxyheptonate aldolase	K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10]
D      Natgr_3595 triosephosphate isomerase	K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
C    00052 Galactose metabolism [PATH:nge00052]
D      Natgr_1294 nucleoside-diphosphate-sugar epimerase	K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]
D      Natgr_2994 nucleoside-diphosphate-sugar epimerase	K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]
D      Natgr_1249 nucleoside-diphosphate-sugar epimerase	K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]
D      Natgr_1689 phosphoglucosamine mutase	K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D      Natgr_0459 transcriptional regulator/sugar kinase	K25026 glk; glucokinase [EC:2.7.1.2]
D      Natgr_0070 enolase superfamily enzyme related to L-alanine-DL-glutamate epimerase	K05308 gnaD; gluconate/galactonate dehydratase [EC:4.2.1.140]
D      Natgr_2179 enolase superfamily enzyme related to L-alanine-DL-glutamate epimerase	K05308 gnaD; gluconate/galactonate dehydratase [EC:4.2.1.140]
C    00053 Ascorbate and aldarate metabolism [PATH:nge00053]
D      Natgr_2229 nucleotide sugar dehydrogenase	K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D      Natgr_2683 hypothetical protein	K03079 ulaE; L-ribulose-5-phosphate 3-epimerase [EC:5.1.3.22]
D      Natgr_2669 NAD-dependent aldehyde dehydrogenase	K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D      Natgr_2311 NAD-dependent aldehyde dehydrogenase	K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D      Natgr_2452 NAD dependent epimerase/dehydratase family protein	K19660 araDH; L-arabinose 1-dehydrogenase [NAD(P)+] [EC:1.1.1.376]
C    00500 Starch and sucrose metabolism [PATH:nge00500]
D      Natgr_2896 glycosyltransferase	K13057 treT; trehalose synthase [EC:2.4.1.245]
D      Natgr_3347 trehalose-phosphatase	K01087 otsB; trehalose 6-phosphate phosphatase [EC:3.1.3.12]
D      Natgr_3346 Trehalose-6-phosphate synthase	K16055 TPS; trehalose 6-phosphate synthase/phosphatase [EC:2.4.1.15 3.1.3.12]
D      Natgr_2221 glycosyl hydrolase, glucoamylase	K22934 E3.2.1.28; alpha,alpha-trehalase [EC:3.2.1.28]
D      Natgr_1689 phosphoglucosamine mutase	K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D      Natgr_0459 transcriptional regulator/sugar kinase	K25026 glk; glucokinase [EC:2.7.1.2]
D      Natgr_1014 glucose-6-phosphate isomerase	K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]
C    00520 Amino sugar and nucleotide sugar metabolism [PATH:nge00520]
D      Natgr_3336 glucosamine--fructose-6-phosphate aminotransferase, isomerizing	K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
D      Natgr_3333 phosphoglucosamine mutase	K03431 glmM; phosphoglucosamine mutase [EC:5.4.2.10]
D      Natgr_3335 UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase	K23144 K23144; UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.7.7.24 2.7.7.83 2.3.1.157 2.3.1.276]
D      Natgr_2787 haloacid dehalogenase superfamily enzyme, subfamily IA	K22292 mupP; N-acetyl-D-muramate 6-phosphate phosphatase [EC:3.1.3.105]
D      Natgr_2974 nucleotide sugar dehydrogenase	K02472 wecC; UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase [EC:1.1.1.336]
D      Natgr_0273 UDP-N-acetylglucosamine 2-epimerase	K13019 wbpI; UDP-GlcNAc3NAcA epimerase [EC:5.1.3.23]
D      Natgr_0459 transcriptional regulator/sugar kinase	K25026 glk; glucokinase [EC:2.7.1.2]
D      Natgr_1689 phosphoglucosamine mutase	K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D      Natgr_2229 nucleotide sugar dehydrogenase	K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D      Natgr_1294 nucleoside-diphosphate-sugar epimerase	K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]
D      Natgr_2994 nucleoside-diphosphate-sugar epimerase	K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]
D      Natgr_1249 nucleoside-diphosphate-sugar epimerase	K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]
D      Natgr_1014 glucose-6-phosphate isomerase	K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]
D      Natgr_2976 putative PLP-dependent enzyme possibly involved in cell wall biogenesis	K13010 per; perosamine synthetase [EC:2.6.1.102]
C    00620 Pyruvate metabolism [PATH:nge00620]
D      Natgr_0530 acetate--CoA ligase	K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D      Natgr_0528 acetate--CoA ligase	K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D      Natgr_1583 acyl-CoA synthetase/AMP-acid ligase	K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D      Natgr_3012 acyl-CoA synthetase/AMP-acid ligase	K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D      Natgr_3239 2-oxoacid:acceptor oxidoreductase, alpha subunit	K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D      Natgr_3238 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate family	K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D      Natgr_3122 2-oxoacid:acceptor oxidoreductase, alpha subunit	K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D      Natgr_3123 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate family	K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D      Natgr_1353 pyruvate dehydrogenase E1 component, alpha subunit	K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
D      Natgr_1352 pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase component beta subunit	K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
D      Natgr_1351 pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase component	K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
D      Natgr_1350 dihydrolipoamide dehydrogenase	K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D      Natgr_0653 pyruvate kinase	K00873 PK; pyruvate kinase [EC:2.7.1.40]
D      Natgr_0598 acetyl/propionyl-CoA carboxylase, alpha subunit	K11263 bccA; acetyl-CoA/propionyl-CoA carboxylase, biotin carboxylase, biotin carboxyl carrier protein [EC:6.4.1.2 6.4.1.3 6.3.4.14]
D      Natgr_0377 acylphosphatase	K01512 acyP; acylphosphatase [EC:3.6.1.7]
D      Natgr_2669 NAD-dependent aldehyde dehydrogenase	K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D      Natgr_2311 NAD-dependent aldehyde dehydrogenase	K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D      Natgr_2180 acetyl-CoA hydrolase	K18118 aarC; succinyl-CoA:acetate CoA-transferase [EC:2.8.3.18]
D      Natgr_3230 ADP-forming acetyl coenzyme A synthetase	K24012 acdAB; acetate---CoA ligase (ADP-forming) [EC:6.2.1.13]
D      Natgr_2745 lactoylglutathione lyase-like lyase	K01759 GLO1; lactoylglutathione lyase [EC:4.4.1.5]
D      Natgr_2012 Zn-dependent hydrolase, glyoxylase	K01069 gloB; hydroxyacylglutathione hydrolase [EC:3.1.2.6]
D      Natgr_2587 Zn-dependent hydrolase, glyoxylase	K01069 gloB; hydroxyacylglutathione hydrolase [EC:3.1.2.6]
D      Natgr_0356 malic enzyme	K00029 maeB; malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) [EC:1.1.1.40]
D      Natgr_1710 malate/lactate dehydrogenase	K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D      Natgr_0014 fumarase	K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]
D      Natgr_0444 phosphoenolpyruvate carboxylase	K01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]
D      Natgr_2938 phosphoenolpyruvate carboxykinase (ATP)	K01610 pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49]
D      Natgr_2899 phosphoenolpyruvate synthase	K01007 pps; pyruvate, water dikinase [EC:2.7.9.2]
D      Natgr_3052 phosphoenolpyruvate synthase	K01007 pps; pyruvate, water dikinase [EC:2.7.9.2]
D      Natgr_0823 acetyl-CoA acetyltransferase	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      Natgr_0426 acetyl-CoA acetyltransferase	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      Natgr_1255 acetyl-CoA acetyltransferase	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      Natgr_3067 acetyl-CoA acetyltransferase	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      Natgr_3496 acetyl-CoA acetyltransferase	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      Natgr_0078 isopropylmalate/homocitrate/citramalate synthase	K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13]
C    00630 Glyoxylate and dicarboxylate metabolism [PATH:nge00630]
D      Natgr_0530 acetate--CoA ligase	K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D      Natgr_0528 acetate--CoA ligase	K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D      Natgr_1583 acyl-CoA synthetase/AMP-acid ligase	K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D      Natgr_3012 acyl-CoA synthetase/AMP-acid ligase	K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D      Natgr_1710 malate/lactate dehydrogenase	K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D      Natgr_3706 2-methylcitrate synthase/citrate synthase II	K01647 CS; citrate synthase [EC:2.3.3.1]
D      Natgr_2365 aconitate hydratase, putative, Aquifex type	K01681 ACO; aconitate hydratase [EC:4.2.1.3]
D      Natgr_3359 aconitate hydratase 1	K01681 ACO; aconitate hydratase [EC:4.2.1.3]
D      Natgr_0823 acetyl-CoA acetyltransferase	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      Natgr_0426 acetyl-CoA acetyltransferase	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      Natgr_1255 acetyl-CoA acetyltransferase	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      Natgr_3067 acetyl-CoA acetyltransferase	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      Natgr_3496 acetyl-CoA acetyltransferase	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      Natgr_0541 acyl dehydratase	K17865 croR; 3-hydroxybutyryl-CoA dehydratase [EC:4.2.1.55]
D      Natgr_0367 acyl dehydratase	K17865 croR; 3-hydroxybutyryl-CoA dehydratase [EC:4.2.1.55]
D      Natgr_3119 methylmalonyl-CoA epimerase	K05606 MCEE; methylmalonyl-CoA/ethylmalonyl-CoA epimerase [EC:5.1.99.1]
D      Natgr_3385 acyl dehydratase	K14449 mch; 2-methylfumaryl-CoA hydratase [EC:4.2.1.148]
D      Natgr_0598 acetyl/propionyl-CoA carboxylase, alpha subunit	K11263 bccA; acetyl-CoA/propionyl-CoA carboxylase, biotin carboxylase, biotin carboxyl carrier protein [EC:6.4.1.2 6.4.1.3 6.3.4.14]
D      Natgr_0600 acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	K19312 pccB; acetyl-CoA/propionyl-CoA carboxylase carboxyl transferase subunit [EC:6.4.1.2 6.4.1.3 2.1.3.15]
D      Natgr_0599 hypothetical protein	K22568 pccX; acetyl-CoA/propionyl-CoA carboxylase, PccX subunit [EC:6.4.1.2 6.4.1.3]
D      Natgr_0827 methylmalonyl-CoA mutase family protein	K01849 E5.4.99.2B; methylmalonyl-CoA mutase, C-terminal domain [EC:5.4.99.2]
D      Natgr_1584 methylmalonyl-CoA mutase family protein	K01848 E5.4.99.2A; methylmalonyl-CoA mutase, N-terminal domain [EC:5.4.99.2]
D      Natgr_3115 methylmalonyl-CoA mutase family protein	K01848 E5.4.99.2A; methylmalonyl-CoA mutase, N-terminal domain [EC:5.4.99.2]
D      Natgr_2183 methylaspartate mutase, E subunit	K19268 glmE; methylaspartate mutase epsilon subunit [EC:5.4.99.1]
D      Natgr_3387 methylaspartate mutase, E subunit	K19268 glmE; methylaspartate mutase epsilon subunit [EC:5.4.99.1]
D      Natgr_2479 methylaspartate mutase, S subunit	K01846 glmS; methylaspartate mutase sigma subunit [EC:5.4.99.1]
D      Natgr_2184 methylaspartate mutase, S subunit	K01846 glmS; methylaspartate mutase sigma subunit [EC:5.4.99.1]
D      Natgr_3388 methylaspartate mutase, S subunit	K01846 glmS; methylaspartate mutase sigma subunit [EC:5.4.99.1]
D      Natgr_2182 methylaspartate ammonia-lyase	K04835 mal; methylaspartate ammonia-lyase [EC:4.3.1.2]
D      Natgr_3386 methylaspartate ammonia-lyase	K04835 mal; methylaspartate ammonia-lyase [EC:4.3.1.2]
D      Natgr_3389 putative acyl-CoA transferase/carnitine dehydratase	K19280 mct; succinyl-CoA:mesaconate CoA transferase [EC:2.8.3.26]
D      Natgr_3384 citrate lyase beta subunit	K19281 mcl; beta-methylmalyl-CoA/(S)-malyl-CoA lyase [EC:4.1.3.24]
D      Natgr_3029 putative phosphatase	K01091 gph; phosphoglycolate phosphatase [EC:3.1.3.18]
D      Natgr_3197 putative phosphatase	K01091 gph; phosphoglycolate phosphatase [EC:3.1.3.18]
D      Natgr_2104 haloacid dehalogenase superfamily enzyme, subfamily IA	K01091 gph; phosphoglycolate phosphatase [EC:3.1.3.18]
D      Natgr_2252 sucrose-phosphate phosphatase-like hydrolase, Archaeal	K22223 pgp; phosphoglycolate phosphatase [EC:3.1.3.18]
D      Natgr_3802 serine-pyruvate aminotransferase/archaeal aspartate aminotransferase	K00830 AGXT; alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase [EC:2.6.1.44 2.6.1.45 2.6.1.51]
D      Natgr_3664 glutamate synthase family protein	K00284 GLU; glutamate synthase (ferredoxin) [EC:1.4.7.1]
D      Natgr_2338 glutamine synthetase	K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D      Natgr_3111 glutamine synthetase, type I	K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D      Natgr_3637 glycine/serine hydroxymethyltransferase	K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D      Natgr_2870 glycine cleavage system protein P	K00282 gcvPA; glycine cleavage system P protein (glycine dehydrogenase) subunit 1 [EC:1.4.4.2]
D      Natgr_2871 glycine cleavage system protein P	K00283 gcvPB; glycine cleavage system P protein (glycine dehydrogenase) subunit 2 [EC:1.4.4.2]
D      Natgr_3023 glycine cleavage system T protein	K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]
D      Natgr_2446 folate-binding protein YgfZ	K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]
D      Natgr_1350 dihydrolipoamide dehydrogenase	K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D      Natgr_3022 glycine cleavage system H protein	K02437 gcvH; glycine cleavage system H protein
D      Natgr_3160 putative glycerate kinase	K11529 gck; glycerate 2-kinase [EC:2.7.1.165]
D      Natgr_0733 haloacid dehalogenase superfamily enzyme, subfamily IA	K26210 E3.1.3.109; ribulose-1,5-bisphosphate 5-phosphatase [EC:3.1.3.109]
D      Natgr_0734 ribulose-5-phosphate 4-epimerase-like epimerase or aldolase	K01636 K01636; ribulose 1-phosphate aldolase [EC:4.1.2.-]
D      Natgr_2482 Entner-Doudoroff aldolase	K01625 eda; 2-dehydro-3-deoxyphosphogluconate aldolase / (4S)-4-hydroxy-2-oxoglutarate aldolase [EC:4.1.2.14 4.1.3.42]
D      Natgr_0407 Fe-S-cluster-containing hydrogenase subunit	K00124 fdoH; formate dehydrogenase iron-sulfur subunit
D      Natgr_0409 cytochrome b subunit of formate dehydrogenase	K00127 fdoI; formate dehydrogenase subunit gamma
C    00640 Propanoate metabolism [PATH:nge00640]
D      Natgr_0530 acetate--CoA ligase	K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D      Natgr_0528 acetate--CoA ligase	K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D      Natgr_1583 acyl-CoA synthetase/AMP-acid ligase	K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D      Natgr_3012 acyl-CoA synthetase/AMP-acid ligase	K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D      Natgr_3230 ADP-forming acetyl coenzyme A synthetase	K24012 acdAB; acetate---CoA ligase (ADP-forming) [EC:6.2.1.13]
D      Natgr_1350 dihydrolipoamide dehydrogenase	K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D      Natgr_3239 2-oxoacid:acceptor oxidoreductase, alpha subunit	K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D      Natgr_3238 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate family	K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D      Natgr_0598 acetyl/propionyl-CoA carboxylase, alpha subunit	K11263 bccA; acetyl-CoA/propionyl-CoA carboxylase, biotin carboxylase, biotin carboxyl carrier protein [EC:6.4.1.2 6.4.1.3 6.3.4.14]
D      Natgr_0600 acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	K19312 pccB; acetyl-CoA/propionyl-CoA carboxylase carboxyl transferase subunit [EC:6.4.1.2 6.4.1.3 2.1.3.15]
D      Natgr_0599 hypothetical protein	K22568 pccX; acetyl-CoA/propionyl-CoA carboxylase, PccX subunit [EC:6.4.1.2 6.4.1.3]
D      Natgr_3371 4-aminobutyrate aminotransferase family protein	K00823 puuE; 4-aminobutyrate aminotransferase [EC:2.6.1.19]
D      Natgr_3119 methylmalonyl-CoA epimerase	K05606 MCEE; methylmalonyl-CoA/ethylmalonyl-CoA epimerase [EC:5.1.99.1]
D      Natgr_0827 methylmalonyl-CoA mutase family protein	K01849 E5.4.99.2B; methylmalonyl-CoA mutase, C-terminal domain [EC:5.4.99.2]
D      Natgr_1584 methylmalonyl-CoA mutase family protein	K01848 E5.4.99.2A; methylmalonyl-CoA mutase, N-terminal domain [EC:5.4.99.2]
D      Natgr_3115 methylmalonyl-CoA mutase family protein	K01848 E5.4.99.2A; methylmalonyl-CoA mutase, N-terminal domain [EC:5.4.99.2]
D      Natgr_3688 succinyl-CoA synthetase, beta subunit	K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]
D      Natgr_3687 succinyl-CoA synthetase, alpha subunit	K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]
D      Natgr_2948 methylglyoxal synthase	K01734 mgsA; methylglyoxal synthase [EC:4.2.3.3]
C    00650 Butanoate metabolism [PATH:nge00650]
D      Natgr_0823 acetyl-CoA acetyltransferase	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      Natgr_0426 acetyl-CoA acetyltransferase	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      Natgr_1255 acetyl-CoA acetyltransferase	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      Natgr_3067 acetyl-CoA acetyltransferase	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      Natgr_3496 acetyl-CoA acetyltransferase	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      Natgr_1257 3-hydroxyacyl-CoA dehydrogenase	K00074 paaH; 3-hydroxybutyryl-CoA dehydrogenase [EC:1.1.1.157]
D      Natgr_1582 3-hydroxyacyl-CoA dehydrogenase	K00074 paaH; 3-hydroxybutyryl-CoA dehydrogenase [EC:1.1.1.157]
D      Natgr_1258 enoyl-CoA hydratase/carnithine racemase	K01715 crt; enoyl-CoA hydratase [EC:4.2.1.17]
D      Natgr_0541 acyl dehydratase	K17865 croR; 3-hydroxybutyryl-CoA dehydratase [EC:4.2.1.55]
D      Natgr_0367 acyl dehydratase	K17865 croR; 3-hydroxybutyryl-CoA dehydratase [EC:4.2.1.55]
D      Natgr_0371 poly(R)-hydroxyalkanoic acid synthase, class III, PhaC subunit	K03821 phaC; poly[(R)-3-hydroxyalkanoate] polymerase subunit PhaC [EC:2.3.1.304]
D      Natgr_0370 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E)	K22881 phaE; poly[(R)-3-hydroxyalkanoate] polymerase subunit PhaE
D      Natgr_2292 maleate cis-trans isomerase	K01799 nicE; maleate isomerase [EC:5.2.1.1]
D      Natgr_0478 succinate dehydrogenase/fumarate reductase flavoprotein subunit	K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
D      Natgr_0493 succinate dehydrogenase/fumarate reductase flavoprotein subunit	K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
D      Natgr_0492 succinate dehydrogenase and fumarate reductase iron-sulfur protein	K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
D      Natgr_0490 succinate dehydrogenase, cytochrome b556 subunit	K00241 sdhC; succinate dehydrogenase cytochrome b subunit
D      Natgr_0491 succinate dehydrogenase, hydrophobic anchor subunit	K00242 sdhD; succinate dehydrogenase membrane anchor subunit
D      Natgr_3371 4-aminobutyrate aminotransferase family protein	K00823 puuE; 4-aminobutyrate aminotransferase [EC:2.6.1.19]
D      Natgr_0438 NAD-dependent aldehyde dehydrogenase	K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
D      Natgr_2180 acetyl-CoA hydrolase	K18118 aarC; succinyl-CoA:acetate CoA-transferase [EC:2.8.3.18]
D      Natgr_3239 2-oxoacid:acceptor oxidoreductase, alpha subunit	K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D      Natgr_3238 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate family	K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D      Natgr_3122 2-oxoacid:acceptor oxidoreductase, alpha subunit	K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D      Natgr_3123 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate family	K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D      Natgr_1254 3-hydroxy-3-methylglutaryl CoA synthase	K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10]
D      Natgr_2866 3-hydroxy-3-methylglutaryl CoA synthase	K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10]
D      Natgr_0896 thiamine pyrophosphate-dependent enzyme, possible carboligase or decarboxylase	K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D      Natgr_0079 acetolactate synthase, large subunit, biosynthetic type	K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D      Natgr_1250 thiamine pyrophosphate-dependent enzyme, possible carboligase or decarboxylase	K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D      Natgr_0080 acetolactate synthase, small subunit	K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6]
C    00660 C5-Branched dibasic acid metabolism [PATH:nge00660]
D      Natgr_0896 thiamine pyrophosphate-dependent enzyme, possible carboligase or decarboxylase	K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D      Natgr_0079 acetolactate synthase, large subunit, biosynthetic type	K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D      Natgr_1250 thiamine pyrophosphate-dependent enzyme, possible carboligase or decarboxylase	K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D      Natgr_0080 acetolactate synthase, small subunit	K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6]
D      Natgr_3688 succinyl-CoA synthetase, beta subunit	K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]
D      Natgr_3687 succinyl-CoA synthetase, alpha subunit	K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]
D      Natgr_2181 acyl dehydratase	K18290 ich-Y; itaconyl-CoA hydratase [EC:4.2.1.56]
D      Natgr_2182 methylaspartate ammonia-lyase	K04835 mal; methylaspartate ammonia-lyase [EC:4.3.1.2]
D      Natgr_3386 methylaspartate ammonia-lyase	K04835 mal; methylaspartate ammonia-lyase [EC:4.3.1.2]
D      Natgr_2183 methylaspartate mutase, E subunit	K19268 glmE; methylaspartate mutase epsilon subunit [EC:5.4.99.1]
D      Natgr_3387 methylaspartate mutase, E subunit	K19268 glmE; methylaspartate mutase epsilon subunit [EC:5.4.99.1]
D      Natgr_2479 methylaspartate mutase, S subunit	K01846 glmS; methylaspartate mutase sigma subunit [EC:5.4.99.1]
D      Natgr_2184 methylaspartate mutase, S subunit	K01846 glmS; methylaspartate mutase sigma subunit [EC:5.4.99.1]
D      Natgr_3388 methylaspartate mutase, S subunit	K01846 glmS; methylaspartate mutase sigma subunit [EC:5.4.99.1]
D      Natgr_3384 citrate lyase beta subunit	K19281 mcl; beta-methylmalyl-CoA/(S)-malyl-CoA lyase [EC:4.1.3.24]
D      Natgr_3385 acyl dehydratase	K14449 mch; 2-methylfumaryl-CoA hydratase [EC:4.2.1.148]
D      Natgr_0336 isopropylmalate/homocitrate/citramalate synthase	K09011 cimA; (R)-citramalate synthase [EC:2.3.3.21]
D      Natgr_0083 3-isopropylmalate dehydratase, large subunit	K01703 leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]
D      Natgr_0084 3-isopropylmalate dehydratase, small subunit	K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35]
D      Natgr_0087 isocitrate/isopropylmalate dehydrogenase	K00052 leuB; 3-isopropylmalate dehydrogenase [EC:1.1.1.85]
C    00562 Inositol phosphate metabolism [PATH:nge00562]
D      Natgr_0330 inositol monophosphatase/fructose-1,6-bisphosphatase family protein	K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25]
D      Natgr_0202 inositol monophosphatase/fructose-1,6-bisphosphatase family protein	K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25]
D      Natgr_1371 inositol monophosphatase/fructose-1,6-bisphosphatase family protein	K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25]
D      Natgr_3595 triosephosphate isomerase	K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
B
B  09102 Energy metabolism
C    00190 Oxidative phosphorylation [PATH:nge00190]
D      Natgr_0867 NADH:ubiquinone oxidoreductase subunit 3 (chain A)	K00330 nuoA; NADH-quinone oxidoreductase subunit A [EC:7.1.1.2]
D      Natgr_0866 NADH-quinone oxidoreductase, B subunit	K00331 nuoB; NADH-quinone oxidoreductase subunit B [EC:7.1.1.2]
D      Natgr_0759 NADH:ubiquinone oxidoreductase 49 kD subunit 7	K13378 nuoCD; NADH-quinone oxidoreductase subunit C/D [EC:7.1.1.2]
D      Natgr_0865 NADH:ubiquinone oxidoreductase 49 kD subunit 7	K13378 nuoCD; NADH-quinone oxidoreductase subunit C/D [EC:7.1.1.2]
D      Natgr_0864 NADH:ubiquinone oxidoreductase subunit 1 (chain H)	K00337 nuoH; NADH-quinone oxidoreductase subunit H [EC:7.1.1.2]
D      Natgr_0863 NADH:ubiquinone oxidoreductase chain I-like protein	K00338 nuoI; NADH-quinone oxidoreductase subunit I [EC:7.1.1.2]
D      Natgr_0861 hypothetical protein	K00339 nuoJ; NADH-quinone oxidoreductase subunit J [EC:7.1.1.2]
D      Natgr_0860 NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K)	K00340 nuoK; NADH-quinone oxidoreductase subunit K [EC:7.1.1.2]
D      Natgr_0859 proton-translocating NADH-quinone oxidoreductase, chain L	K00341 nuoL; NADH-quinone oxidoreductase subunit L [EC:7.1.1.2]
D      Natgr_0857 proton-translocating NADH-quinone oxidoreductase, chain N	K00343 nuoN; NADH-quinone oxidoreductase subunit N [EC:7.1.1.2]
D      Natgr_0719 NADH dehydrogenase, FAD-containing subunit	K03885 ndh; NADH:quinone reductase (non-electrogenic) [EC:1.6.5.9]
D      Natgr_0179 NADH dehydrogenase, FAD-containing subunit	K03885 ndh; NADH:quinone reductase (non-electrogenic) [EC:1.6.5.9]
D      Natgr_0478 succinate dehydrogenase/fumarate reductase flavoprotein subunit	K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
D      Natgr_0493 succinate dehydrogenase/fumarate reductase flavoprotein subunit	K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
D      Natgr_0492 succinate dehydrogenase and fumarate reductase iron-sulfur protein	K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
D      Natgr_0490 succinate dehydrogenase, cytochrome b556 subunit	K00241 sdhC; succinate dehydrogenase cytochrome b subunit
D      Natgr_0491 succinate dehydrogenase, hydrophobic anchor subunit	K00242 sdhD; succinate dehydrogenase membrane anchor subunit
D      Natgr_0675 protoheme IX farnesyltransferase	K02257 COX10; heme o synthase [EC:2.5.1.141]
D      Natgr_1827 heme/copper-type cytochrome/quinol oxidase, subunit 1	K02274 coxA; cytochrome c oxidase subunit I [EC:7.1.1.9]
D      Natgr_0137 heme/copper-type cytochrome/quinol oxidase, subunit 1	K15408 coxAC; cytochrome c oxidase subunit I+III [EC:7.1.1.9]
D      Natgr_0138 cytochrome c oxidase, subunit II	K02275 coxB; cytochrome c oxidase subunit II [EC:7.1.1.9]
D      Natgr_1826 heme/copper-type cytochrome/quinol oxidases, subunit 2	K02275 coxB; cytochrome c oxidase subunit II [EC:7.1.1.9]
D      Natgr_0042 heme/copper-type cytochrome/quinol oxidases, subunit 2	K02275 coxB; cytochrome c oxidase subunit II [EC:7.1.1.9]
D      Natgr_0392 uncharacterized protein required for cytochrome oxidase assembly	K02259 COX15; heme a synthase [EC:1.17.99.9]
D      Natgr_0317 cytochrome bd-type quinol oxidase, subunit 1	K00425 cydA; cytochrome bd ubiquinol oxidase subunit I [EC:7.1.1.7]
D      Natgr_3146 cytochrome bd-type quinol oxidase, subunit 1	K00425 cydA; cytochrome bd ubiquinol oxidase subunit I [EC:7.1.1.7]
D      Natgr_0318 cytochrome bd-type quinol oxidase, subunit 2	K00426 cydB; cytochrome bd ubiquinol oxidase subunit II [EC:7.1.1.7]
D      Natgr_3145 cytochrome d oxidase cyd, subunit II	K00426 cydB; cytochrome bd ubiquinol oxidase subunit II [EC:7.1.1.7]
D      Natgr_1976 ATP synthase, A subunit	K02117 ATPVA; V/A-type H+/Na+-transporting ATPase subunit A [EC:7.1.2.2 7.2.2.1]
D      Natgr_1975 ATP synthase, B subunit	K02118 ATPVB; V/A-type H+/Na+-transporting ATPase subunit B
D      Natgr_1978 ATP synthase A1, C subunit	K02119 ATPVC; V/A-type H+/Na+-transporting ATPase subunit C
D      Natgr_1974 H(+)-transporting ATP synthase, vacuolar type, subunit D	K02120 ATPVD; V/A-type H+/Na+-transporting ATPase subunit D
D      Natgr_1979 archaeal/vacuolar-type H+-ATPase subunit E	K02121 ATPVE; V/A-type H+/Na+-transporting ATPase subunit E
D      Natgr_1977 archaeal/vacuolar-type H+-ATPase subunit F	K02122 ATPVF; V/A-type H+/Na+-transporting ATPase subunit F
D      Natgr_1982 ATP synthase, H subunit	K02107 ATPVG; V/A-type H+/Na+-transporting ATPase subunit G/H
D      Natgr_1981 archaeal/vacuolar-type H+-ATPase subunit I	K02123 ATPVI; V/A-type H+/Na+-transporting ATPase subunit I
D      Natgr_1980 ATP synthase subunit C	K02124 ATPVK; V/A-type H+/Na+-transporting ATPase subunit K
D      Natgr_2540 inorganic pyrophosphatase	K01507 ppa; inorganic pyrophosphatase [EC:3.6.1.1]
C    00195 Photosynthesis
C    00196 Photosynthesis - antenna proteins
C    00710 Carbon fixation in photosynthetic organisms
C    00720 Carbon fixation pathways in prokaryotes [PATH:nge00720]
D      Natgr_3239 2-oxoacid:acceptor oxidoreductase, alpha subunit	K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D      Natgr_3238 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate family	K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D      Natgr_2899 phosphoenolpyruvate synthase	K01007 pps; pyruvate, water dikinase [EC:2.7.9.2]
D      Natgr_3052 phosphoenolpyruvate synthase	K01007 pps; pyruvate, water dikinase [EC:2.7.9.2]
D      Natgr_0444 phosphoenolpyruvate carboxylase	K01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]
D      Natgr_1710 malate/lactate dehydrogenase	K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D      Natgr_0014 fumarase	K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]
D      Natgr_0478 succinate dehydrogenase/fumarate reductase flavoprotein subunit	K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
D      Natgr_0493 succinate dehydrogenase/fumarate reductase flavoprotein subunit	K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
D      Natgr_0492 succinate dehydrogenase and fumarate reductase iron-sulfur protein	K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
D      Natgr_0490 succinate dehydrogenase, cytochrome b556 subunit	K00241 sdhC; succinate dehydrogenase cytochrome b subunit
D      Natgr_0491 succinate dehydrogenase, hydrophobic anchor subunit	K00242 sdhD; succinate dehydrogenase membrane anchor subunit
D      Natgr_3687 succinyl-CoA synthetase, alpha subunit	K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]
D      Natgr_3688 succinyl-CoA synthetase, beta subunit	K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]
D      Natgr_0470 3-hydroxyacyl-CoA dehydrogenase	K15016 K15016; enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase [EC:4.2.1.17 1.1.1.35]
D      Natgr_0823 acetyl-CoA acetyltransferase	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      Natgr_0426 acetyl-CoA acetyltransferase	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      Natgr_1255 acetyl-CoA acetyltransferase	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      Natgr_3067 acetyl-CoA acetyltransferase	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      Natgr_3496 acetyl-CoA acetyltransferase	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      Natgr_3122 2-oxoacid:acceptor oxidoreductase, alpha subunit	K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D      Natgr_3123 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate family	K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D      Natgr_1115 isocitrate dehydrogenase, NADP-dependent, prokaryotic type	K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]
D      Natgr_2365 aconitate hydratase, putative, Aquifex type	K01681 ACO; aconitate hydratase [EC:4.2.1.3]
D      Natgr_3359 aconitate hydratase 1	K01681 ACO; aconitate hydratase [EC:4.2.1.3]
D      Natgr_3385 acyl dehydratase	K14449 mch; 2-methylfumaryl-CoA hydratase [EC:4.2.1.148]
D      Natgr_3119 methylmalonyl-CoA epimerase	K05606 MCEE; methylmalonyl-CoA/ethylmalonyl-CoA epimerase [EC:5.1.99.1]
D      Natgr_1584 methylmalonyl-CoA mutase family protein	K01848 E5.4.99.2A; methylmalonyl-CoA mutase, N-terminal domain [EC:5.4.99.2]
D      Natgr_3115 methylmalonyl-CoA mutase family protein	K01848 E5.4.99.2A; methylmalonyl-CoA mutase, N-terminal domain [EC:5.4.99.2]
D      Natgr_0827 methylmalonyl-CoA mutase family protein	K01849 E5.4.99.2B; methylmalonyl-CoA mutase, C-terminal domain [EC:5.4.99.2]
D      Natgr_0650 formyltetrahydrofolate synthetase	K01938 fhs; formate--tetrahydrofolate ligase [EC:6.3.4.3]
D      Natgr_2920 formyltetrahydrofolate synthetase	K01938 fhs; formate--tetrahydrofolate ligase [EC:6.3.4.3]
D      Natgr_3636 5,10-methylene-tetrahydrofolate dehydrogenase/methenyl tetrahydrofolate cyclohydrolase	K01491 folD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9]
D      Natgr_2906 5,10-methylenetetrahydrofolate reductase	K00297 metF; methylenetetrahydrofolate reductase (NADH) [EC:1.5.1.54]
D      Natgr_0530 acetate--CoA ligase	K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D      Natgr_0528 acetate--CoA ligase	K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D      Natgr_1583 acyl-CoA synthetase/AMP-acid ligase	K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D      Natgr_3012 acyl-CoA synthetase/AMP-acid ligase	K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
C    00680 Methane metabolism [PATH:nge00680]
D      Natgr_0407 Fe-S-cluster-containing hydrogenase subunit	K00124 fdoH; formate dehydrogenase iron-sulfur subunit
D      Natgr_0409 cytochrome b subunit of formate dehydrogenase	K00127 fdoI; formate dehydrogenase subunit gamma
D      Natgr_0651 putative anaerobic dehydrogenase	K22516 fdhA; formate dehydrogenase (coenzyme F420) alpha subunit [EC:1.17.98.3 1.8.98.6]
D      Natgr_2918 formate dehydrogenase, alpha subunit, archaeal-type	K22516 fdhA; formate dehydrogenase (coenzyme F420) alpha subunit [EC:1.17.98.3 1.8.98.6]
D      Natgr_3637 glycine/serine hydroxymethyltransferase	K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D      Natgr_3802 serine-pyruvate aminotransferase/archaeal aspartate aminotransferase	K00830 AGXT; alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase [EC:2.6.1.44 2.6.1.45 2.6.1.51]
D      Natgr_3160 putative glycerate kinase	K11529 gck; glycerate 2-kinase [EC:2.7.1.165]
D      Natgr_2561 phosphopyruvate hydratase	K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D      Natgr_0444 phosphoenolpyruvate carboxylase	K01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]
D      Natgr_1710 malate/lactate dehydrogenase	K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D      Natgr_2902 DhnA-type fructose-1,6-bisphosphate aldolase-like enzyme	K11645 fbaB; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D      Natgr_0761 putative phospho-2-dehydro-3-deoxyheptonate aldolase	K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10]
D      Natgr_2901 fructose-1,6-bisphosphatase	K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]
D      Natgr_2898 archaeal ADP-dependent phosphofructokinase/glucokinase	K00918 pfkC; ADP-dependent phosphofructokinase/glucokinase [EC:2.7.1.146 2.7.1.147]
D      Natgr_2851 methenyltetrahydromethanopterin cyclohydrolase	K01499 mch; methenyltetrahydromethanopterin cyclohydrolase [EC:3.5.4.27]
D      Natgr_2297 flavin-dependent oxidoreductase, F420-dependent methylene-tetrahydromethanopterin reductase	K00320 mer; 5,10-methylenetetrahydromethanopterin reductase [EC:1.5.98.2]
D      Natgr_2860 polyferredoxin, heterodixulfide reductase subunit A	K03388 hdrA2; heterodisulfide reductase subunit A2 [EC:1.8.7.3 1.8.98.4 1.8.98.5 1.8.98.6]
D      Natgr_2861 coenzyme F420-reducing hydrogenase, delta subunit	K14127 mvhD; F420-non-reducing hydrogenase iron-sulfur subunit [EC:1.12.99.- 1.8.98.5 1.8.98.6]
D      Natgr_2863 coenzyme F420-reducing hydrogenase, alpha subunit	K14126 mvhA; F420-non-reducing hydrogenase large subunit [EC:1.12.99.- 1.8.98.5]
D      Natgr_2862 coenzyme F420-reducing hydrogenase, gamma subunit	K14128 mvhG; F420-non-reducing hydrogenase small subunit [EC:1.12.99.- 1.8.98.5]
D      Natgr_0530 acetate--CoA ligase	K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D      Natgr_0528 acetate--CoA ligase	K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D      Natgr_1583 acyl-CoA synthetase/AMP-acid ligase	K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D      Natgr_3012 acyl-CoA synthetase/AMP-acid ligase	K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D      Natgr_3239 2-oxoacid:acceptor oxidoreductase, alpha subunit	K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D      Natgr_3238 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate family	K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D      Natgr_2899 phosphoenolpyruvate synthase	K01007 pps; pyruvate, water dikinase [EC:2.7.9.2]
D      Natgr_3052 phosphoenolpyruvate synthase	K01007 pps; pyruvate, water dikinase [EC:2.7.9.2]
D      Natgr_2688 2,3-bisphosphoglycerate-independent phosphoglycerate mutase	K15633 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]
D      Natgr_1696 D-3-phosphoglycerate dehydrogenase	K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
D      Natgr_3368 lactate dehydrogenase-like oxidoreductase	K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
D      Natgr_1427 phosphoserine phosphatase SerB	K01079 serB; phosphoserine phosphatase [EC:3.1.3.3]
D      Natgr_1100 radical SAM domain protein, CofH subfamily	K11781 cofH; 5-amino-6-(D-ribitylamino)uracil---L-tyrosine 4-hydroxyphenyl transferase [EC:2.5.1.147]
D      Natgr_1125 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofG subunit	K11780 cofG; 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase [EC:4.3.1.32]
D      Natgr_1126 2-phospho-L-lactate guanylyltransferase	K14941 cofC; 2-phospho-L-lactate/phosphoenolpyruvate guanylyltransferase [EC:2.7.7.68 2.7.7.105]
D      Natgr_0322 LPPG:FO 2-phospho-L-lactate transferase	K11212 cofD; LPPG:FO 2-phospho-L-lactate transferase [EC:2.7.8.28]
D      Natgr_2296 F420-0:gamma-glutamyl ligase	K12234 cofE; coenzyme F420-0:L-glutamate ligase / coenzyme F420-1:gamma-L-glutamate ligase [EC:6.3.2.31 6.3.2.34]
D      Natgr_3048 tyrosine decarboxylase MnfA	K18933 mfnA; tyrosine decarboxylase / aspartate 1-decarboxylase [EC:4.1.1.25 4.1.1.11]
C    00910 Nitrogen metabolism [PATH:nge00910]
D      Natgr_3303 hydroxylamine reductase	K05601 hcp; hydroxylamine reductase [EC:1.7.99.1]
D      Natgr_0577 glutamate dehydrogenase/leucine dehydrogenase	K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]
D      Natgr_2884 glutamate dehydrogenase/leucine dehydrogenase	K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]
D      Natgr_2338 glutamine synthetase	K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D      Natgr_3111 glutamine synthetase, type I	K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D      Natgr_3664 glutamate synthase family protein	K00284 GLU; glutamate synthase (ferredoxin) [EC:1.4.7.1]
D      Natgr_0688 carbamate kinase	K00926 arcC; carbamate kinase [EC:2.7.2.2]
D      Natgr_1672 carbonic anhydrase	K01673 cynT; carbonic anhydrase [EC:4.2.1.1]
C    00920 Sulfur metabolism [PATH:nge00920]
D      Natgr_0272 PAPS reductase/FAD synthetase family protein	K00390 cysH; phosphoadenosine phosphosulfate reductase [EC:1.8.4.8 1.8.4.10]
D      Natgr_3158 NAD(FAD)-dependent dehydrogenase	K17218 sqr; sulfide:quinone oxidoreductase [EC:1.8.5.4]
D      Natgr_1156 DoxX protein	K16937 doxD; thiosulfate dehydrogenase (quinone) large subunit [EC:1.8.5.2]
D      Natgr_0551 anaerobic dehydrogenase, typically selenocysteine-containing	K08352 phsA; thiosulfate reductase / polysulfide reductase chain A [EC:1.8.5.5]
D      Natgr_2276 anaerobic dehydrogenase, typically selenocysteine-containing	K08352 phsA; thiosulfate reductase / polysulfide reductase chain A [EC:1.8.5.5]
D      Natgr_2191 rhodanese-related sulfurtransferase	K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]
D      Natgr_3159 rhodanese-related sulfurtransferase	K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]
D      Natgr_3655 rhodanese-related sulfurtransferase	K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]
D      Natgr_1764 serine O-acetyltransferase	K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30]
D      Natgr_2905 serine acetyltransferase	K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30]
D      Natgr_0995 cysteine synthase A	K01738 cysK; cysteine synthase [EC:2.5.1.47]
D      Natgr_3352 cysteine synthase	K01738 cysK; cysteine synthase [EC:2.5.1.47]
D      Natgr_1425 homoserine O-acetyltransferase	K00641 metX; homoserine O-acetyltransferase/O-succinyltransferase [EC:2.3.1.31 2.3.1.46]
D      Natgr_2518 anaerobic dehydrogenase, typically selenocysteine-containing	K07306 dmsA; anaerobic dimethyl sulfoxide reductase subunit A [EC:1.8.5.3]
D      Natgr_2519 Fe-S-cluster-containing hydrogenase subunit	K00184 dmsB; dimethyl sulfoxide reductase iron-sulfur subunit
D      Natgr_2520 polysulfide reductase	K00185 dmsC; dimethyl sulfoxide reductase membrane subunit
B
B  09103 Lipid metabolism
C    00061 Fatty acid biosynthesis [PATH:nge00061]
D      Natgr_0598 acetyl/propionyl-CoA carboxylase, alpha subunit	K11263 bccA; acetyl-CoA/propionyl-CoA carboxylase, biotin carboxylase, biotin carboxyl carrier protein [EC:6.4.1.2 6.4.1.3 6.3.4.14]
D      Natgr_0372 dehydrogenase of unknown specificity, short-chain alcohol dehydrogenase like protein	K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D      Natgr_0427 dehydrogenase of unknown specificity, short-chain alcohol dehydrogenase like protein	K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D      Natgr_3259 dehydrogenase of unknown specificity, short-chain alcohol dehydrogenase like protein	K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D      Natgr_0594 dehydrogenase of unknown specificity, short-chain alcohol dehydrogenase like protein	K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D      Natgr_2199 short-chain alcohol dehydrogenase	K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D      Natgr_1229 AMP-forming long-chain acyl-CoA synthetase	K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D      Natgr_1230 AMP-forming long-chain acyl-CoA synthetase	K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
C    00062 Fatty acid elongation
C    00071 Fatty acid degradation [PATH:nge00071]
D      Natgr_0823 acetyl-CoA acetyltransferase	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      Natgr_0426 acetyl-CoA acetyltransferase	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      Natgr_1255 acetyl-CoA acetyltransferase	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      Natgr_3067 acetyl-CoA acetyltransferase	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      Natgr_3496 acetyl-CoA acetyltransferase	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      Natgr_1273 acetyl-CoA acetyltransferase	K00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16]
D      Natgr_0502 acyl-CoA dehydrogenase	K00249 ACADM; acyl-CoA dehydrogenase [EC:1.3.8.7]
D      Natgr_1167 acyl-CoA dehydrogenase	K00252 GCDH; glutaryl-CoA dehydrogenase [EC:1.3.8.6]
D      Natgr_1229 AMP-forming long-chain acyl-CoA synthetase	K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D      Natgr_1230 AMP-forming long-chain acyl-CoA synthetase	K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D      Natgr_2669 NAD-dependent aldehyde dehydrogenase	K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D      Natgr_2311 NAD-dependent aldehyde dehydrogenase	K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
C    00073 Cutin, suberine and wax biosynthesis
C    00100 Steroid biosynthesis [PATH:nge00100]
D      Natgr_0050 phytoene/squalene synthetase	K00801 FDFT1; farnesyl-diphosphate farnesyltransferase [EC:2.5.1.21]
C    00120 Primary bile acid biosynthesis
C    00121 Secondary bile acid biosynthesis
C    00140 Steroid hormone biosynthesis
C    00561 Glycerolipid metabolism [PATH:nge00561]
D      Natgr_3160 putative glycerate kinase	K11529 gck; glycerate 2-kinase [EC:2.7.1.165]
D      Natgr_2669 NAD-dependent aldehyde dehydrogenase	K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D      Natgr_2311 NAD-dependent aldehyde dehydrogenase	K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
C    00564 Glycerophospholipid metabolism [PATH:nge00564]
D      Natgr_2828 glycerophosphoryl diester phosphodiesterase	K01126 E3.1.4.46; glycerophosphoryl diester phosphodiesterase [EC:3.1.4.46]
D      Natgr_2347 glycerophosphoryl diester phosphodiesterase	K01126 E3.1.4.46; glycerophosphoryl diester phosphodiesterase [EC:3.1.4.46]
D      Natgr_0932 methylase involved in ubiquinone/menaquinone biosynthesis	K00570 pmtA; phosphatidylethanolamine/phosphatidyl-N-methylethanolamine N-methyltransferase [EC:2.1.1.17 2.1.1.71]
D      Natgr_3287 phosphatidylserine decarboxylase	K01613 psd; phosphatidylserine decarboxylase [EC:4.1.1.65]
D      Natgr_3298 phosphatidylglycerophosphate synthase	K00995 pgsA; CDP-diacylglycerol---glycerol-3-phosphate 3-phosphatidyltransferase [EC:2.7.8.5]
D      Natgr_3656 glycerol dehydrogenase-like oxidoreductase	K00096 araM; glycerol-1-phosphate dehydrogenase [NAD(P)+] [EC:1.1.1.261]
D      Natgr_1269 phosphoglycerol geranylgeranyltransferase, putative	K17104 E2.5.1.41; phosphoglycerol geranylgeranyltransferase [EC:2.5.1.41]
D      Natgr_2083 phosphoglycerol geranylgeranyltransferase, putative	K17104 E2.5.1.41; phosphoglycerol geranylgeranyltransferase [EC:2.5.1.41]
D      Natgr_0591 geranylgeranylglyceryl phosphate synthase family protein	K17104 E2.5.1.41; phosphoglycerol geranylgeranyltransferase [EC:2.5.1.41]
D      Natgr_0626 4-hydroxybenzoate polyprenyltransferase-like prenyltransferase	K17105 E2.5.1.42; geranylgeranylglycerol-phosphate geranylgeranyltransferase [EC:2.5.1.42]
D      Natgr_2464 CDP-diglyceride synthetase	K19664 carS; CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase [EC:2.7.7.67]
D      Natgr_0924 phosphatidylserine synthase	K19665 pssA; archaetidylserine synthase [EC:2.7.8.38]
D      Natgr_0786 flavin-dependent dehydrogenase	K17830 GGR; digeranylgeranylglycerophospholipid reductase [EC:1.3.1.101 1.3.7.11]
D      Natgr_1266 geranylgeranyl reductase family protein	K17830 GGR; digeranylgeranylglycerophospholipid reductase [EC:1.3.1.101 1.3.7.11]
D      Natgr_3103 geranylgeranyl reductase family protein	K17830 GGR; digeranylgeranylglycerophospholipid reductase [EC:1.3.1.101 1.3.7.11]
C    00565 Ether lipid metabolism
C    00600 Sphingolipid metabolism
C    00590 Arachidonic acid metabolism
C    00591 Linoleic acid metabolism
C    00592 alpha-Linolenic acid metabolism [PATH:nge00592]
D      Natgr_1273 acetyl-CoA acetyltransferase	K00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16]
C    01040 Biosynthesis of unsaturated fatty acids
B
B  09104 Nucleotide metabolism
C    00230 Purine metabolism [PATH:nge00230]
D      Natgr_1058 NTP pyrophosphohydrolase	K01515 nudF; ADP-ribose diphosphatase [EC:3.6.1.13 3.6.1.-]
D      Natgr_1905 ADP-ribose pyrophosphatase	K01515 nudF; ADP-ribose diphosphatase [EC:3.6.1.13 3.6.1.-]
D      Natgr_0366 phosphomannomutase	K22199 ppm; phosphopentomutase [EC:5.4.2.7]
D      Natgr_1689 phosphoglucosamine mutase	K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D      Natgr_1686 ribose-phosphate pyrophosphokinase	K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
D      Natgr_2174 amidophosphoribosyltransferase	K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
D      Natgr_3369 phosphoribosylamine--glycine ligase	K01945 purD; phosphoribosylamine---glycine ligase [EC:6.3.4.13]
D      Natgr_0994 AICAR transformylase/IMP cyclohydrolase PurH	K01492 purNH; phosphoribosylglycinamide/phosphoribosylaminoimidazolecarboxamide formyltransferase [EC:2.1.2.2 2.1.2.3]
D      Natgr_3237 phosphoribosylformylglycinamidine synthase II	K23269 purL; phosphoribosylformylglycinamidine synthase subunit PurL [EC:6.3.5.3]
D      Natgr_1086 phosphoribosylformylglycinamidine synthase, purS protein	K23264 purS; phosphoribosylformylglycinamidine synthase subunit PurS [EC:6.3.5.3]
D      Natgr_1085 phosphoribosylformylglycinamidine synthase I	K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2]
D      Natgr_3219 phosphoribosylaminoimidazole synthetase	K01933 purM; phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.3.1]
D      Natgr_0869 phosphoribosylaminoimidazole carboxylase, PurK protein	K01589 purK; 5-(carboxyamino)imidazole ribonucleotide synthase [EC:6.3.4.18]
D      Natgr_0868 phosphoribosylcarboxyaminoimidazole (NCAIR) mutase	K01588 purE; 5-(carboxyamino)imidazole ribonucleotide mutase [EC:5.4.99.18]
D      Natgr_1098 phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase	K01923 purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:6.3.2.6]
D      Natgr_0993 adenylosuccinate lyase	K01756 purB; adenylosuccinate lyase [EC:4.3.2.2]
D      Natgr_1767 IMP cyclohydrolase	K11176 purO; IMP cyclohydrolase [EC:3.5.4.10]
D      Natgr_0812 PRPP-binding protein, adenine/guanine phosphoribosyltransferase	K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7]
D      Natgr_2478 PRPP-binding protein, adenine/guanine phosphoribosyltransferase	K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7]
D      Natgr_0839 5'/3'-nucleotidase SurE	K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6]
D      Natgr_0229 5'/3'-nucleotidase SurE	K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6]
D      Natgr_2810 IMP dehydrogenase/GMP reductase	K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]
D      Natgr_3267 inosine-5''-monophosphate dehydrogenase	K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]
D      Natgr_2582 nucleoside diphosphate kinase	K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
D      Natgr_1037 inosine/xanthosine triphosphatase	K01529 yjjX; inosine/xanthosine triphosphatase [EC:3.6.1.73]
D      Natgr_2378 non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family	K01519 rdgB; XTP/dITP diphosphohydrolase [EC:3.6.1.66]
D      Natgr_0737 GMP synthase, glutamine-hydrolyzing, N-terminal domain or A subunit	K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D      Natgr_1007 GMP synthase, glutamine-hydrolyzing, C-terminal domain or B subunit	K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D      Natgr_1629 GMP synthase family protein	K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D      Natgr_1137 uridine phosphorylase	K26212 K26212; guanosine phosphorylase [EC:2.4.2.15]
D      Natgr_3765 ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent	K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D      Natgr_2172 hypothetical protein	K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D      Natgr_0134 adenylyl cyclase CyaB, putative	K05873 cyaB; adenylate cyclase, class 2 [EC:4.6.1.1]
D      Natgr_0850 adenylosuccinate synthase	K01939 purA; adenylosuccinate synthase [EC:6.3.4.4]
D      Natgr_0140 adenylate kinase family protein	K00939 adk; adenylate kinase [EC:2.7.4.3]
D      Natgr_3599 putative nucleoside kinase, CMP and AMP kinase	K18532 AK6; adenylate kinase [EC:2.7.4.3]
D      Natgr_1122 HIT family hydrolase, diadenosine tetraphosphate hydrolase	K19710 E2.7.7.53; ATP adenylyltransferase [EC:2.7.7.53]
D      Natgr_2995 allantoinase	K01466 allB; allantoinase [EC:3.5.2.5]
D      Natgr_0688 carbamate kinase	K00926 arcC; carbamate kinase [EC:2.7.2.2]
C    00240 Pyrimidine metabolism [PATH:nge00240]
D      Natgr_3603 carbamoyl-phosphate synthase, large subunit	K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]
D      Natgr_0998 carbamoyl-phosphate synthase, small subunit	K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]
D      Natgr_0696 aspartate carbamoyltransferase	K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2]
D      Natgr_0695 aspartate carbamoyltransferase, regulatory subunit	K00610 pyrI; aspartate carbamoyltransferase regulatory subunit
D      Natgr_2997 dihydroorotate dehydrogenase, subfamily 2	K00254 DHODH; dihydroorotate dehydrogenase [EC:1.3.5.2]
D      Natgr_2466 orotate phosphoribosyltransferase	K00762 pyrE; orotate phosphoribosyltransferase [EC:2.4.2.10]
D      Natgr_2844 orotidine 5''-phosphate decarboxylase, subfamily 2	K01591 pyrF; orotidine-5'-phosphate decarboxylase [EC:4.1.1.23]
D      Natgr_2417 uridylate kinase, putative	K09903 pyrH; uridylate kinase [EC:2.7.4.22]
D      Natgr_2582 nucleoside diphosphate kinase	K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
D      Natgr_1008 CTP synthase	K01937 pyrG; CTP synthase [EC:6.3.4.2]
D      Natgr_0144 cytidylate kinase, putative	K00945 cmk; CMP/dCMP kinase [EC:2.7.4.25]
D      Natgr_3266 cytidylate kinase, putative	K00945 cmk; CMP/dCMP kinase [EC:2.7.4.25]
D      Natgr_2806 uridine kinase	K00876 udk; uridine kinase [EC:2.7.1.48]
D      Natgr_0839 5'/3'-nucleotidase SurE	K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6]
D      Natgr_0229 5'/3'-nucleotidase SurE	K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6]
D      Natgr_0363 uridine phosphorylase	K00757 udp; uridine phosphorylase [EC:2.4.2.3]
D      Natgr_1413 uracil phosphoribosyltransferase	K00761 upp; uracil phosphoribosyltransferase [EC:2.4.2.9]
D      Natgr_0365 cytidine deaminase, homotetrameric	K01489 cdd; cytidine deaminase [EC:3.5.4.5]
D      Natgr_0935 deoxycytidine triphosphate deaminase	K01494 dcd; dCTP deaminase [EC:3.5.4.13]
D      Natgr_3765 ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent	K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D      Natgr_2172 hypothetical protein	K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D      Natgr_2678 thymidylate kinase	K00943 tmk; dTMP kinase [EC:2.7.4.9]
D      Natgr_2366 deoxycytidine deaminase	K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D      Natgr_3361 thymidylate synthase	K00560 thyA; thymidylate synthase [EC:2.1.1.45]
D      Natgr_0462 amidase, hydantoinase/carbamoylase family	K06016 pydC; beta-ureidopropionase / N-carbamoyl-L-amino-acid hydrolase [EC:3.5.1.6 3.5.1.87]
B
B  09105 Amino acid metabolism
C    00250 Alanine, aspartate and glutamate metabolism [PATH:nge00250]
D      Natgr_0871 aspartate/tyrosine/aromatic aminotransferase	K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D      Natgr_2941 aspartate/tyrosine/aromatic aminotransferase	K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D      Natgr_2037 aspartate/tyrosine/aromatic aminotransferase	K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D      Natgr_1145 aspartate oxidase	K00278 nadB; L-aspartate oxidase [EC:1.4.3.16]
D      Natgr_1117 asparaginase	K13051 ASRGL1; L-asparaginase / beta-aspartyl-peptidase [EC:3.5.1.1 3.4.19.5]
D      Natgr_2372 asparagine synthase (glutamine-hydrolyzing)	K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]
D      Natgr_2237 asparagine synthase (glutamine-hydrolyzing)	K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]
D      Natgr_3612 asparagine synthase (glutamine-hydrolyzing)	K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]
D      Natgr_3802 serine-pyruvate aminotransferase/archaeal aspartate aminotransferase	K00830 AGXT; alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase [EC:2.6.1.44 2.6.1.45 2.6.1.51]
D      Natgr_1735 putative ornithine cyclodeaminase, mu-crystallin	K19244 ala; alanine dehydrogenase [EC:1.4.1.1]
D      Natgr_1609 argininosuccinate synthase	K01940 argG; argininosuccinate synthase [EC:6.3.4.5]
D      Natgr_1610 argininosuccinate lyase	K01755 argH; argininosuccinate lyase [EC:4.3.2.1]
D      Natgr_0850 adenylosuccinate synthase	K01939 purA; adenylosuccinate synthase [EC:6.3.4.4]
D      Natgr_0993 adenylosuccinate lyase	K01756 purB; adenylosuccinate lyase [EC:4.3.2.2]
D      Natgr_0696 aspartate carbamoyltransferase	K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2]
D      Natgr_0695 aspartate carbamoyltransferase, regulatory subunit	K00610 pyrI; aspartate carbamoyltransferase regulatory subunit
D      Natgr_3371 4-aminobutyrate aminotransferase family protein	K00823 puuE; 4-aminobutyrate aminotransferase [EC:2.6.1.19]
D      Natgr_0438 NAD-dependent aldehyde dehydrogenase	K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
D      Natgr_0577 glutamate dehydrogenase/leucine dehydrogenase	K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]
D      Natgr_2884 glutamate dehydrogenase/leucine dehydrogenase	K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]
D      Natgr_2338 glutamine synthetase	K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D      Natgr_3111 glutamine synthetase, type I	K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D      Natgr_3603 carbamoyl-phosphate synthase, large subunit	K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]
D      Natgr_0998 carbamoyl-phosphate synthase, small subunit	K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]
D      Natgr_1085 phosphoribosylformylglycinamidine synthase I	K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2]
D      Natgr_3336 glucosamine--fructose-6-phosphate aminotransferase, isomerizing	K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
D      Natgr_2174 amidophosphoribosyltransferase	K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
C    00260 Glycine, serine and threonine metabolism [PATH:nge00260]
D      Natgr_1590 aspartate kinase	K00928 lysC; aspartate kinase [EC:2.7.2.4]
D      Natgr_3787 aspartate-semialdehyde dehydrogenase	K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D      Natgr_0888 homoserine dehydrogenase	K00003 hom; homoserine dehydrogenase [EC:1.1.1.3]
D      Natgr_2127 homoserine kinase	K00872 thrB; homoserine kinase [EC:2.7.1.39]
D      Natgr_1620 threonine synthase	K01733 thrC; threonine synthase [EC:4.2.3.1]
D      Natgr_2082 threonine synthase	K01733 thrC; threonine synthase [EC:4.2.3.1]
D      Natgr_1998 threonine synthase	K01733 thrC; threonine synthase [EC:4.2.3.1]
D      Natgr_2336 threonine synthase	K01733 thrC; threonine synthase [EC:4.2.3.1]
D      Natgr_1817 threonine aldolase	K01620 ltaE; threonine aldolase [EC:4.1.2.48]
D      Natgr_3637 glycine/serine hydroxymethyltransferase	K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D      Natgr_3802 serine-pyruvate aminotransferase/archaeal aspartate aminotransferase	K00830 AGXT; alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase [EC:2.6.1.44 2.6.1.45 2.6.1.51]
D      Natgr_3160 putative glycerate kinase	K11529 gck; glycerate 2-kinase [EC:2.7.1.165]
D      Natgr_2688 2,3-bisphosphoglycerate-independent phosphoglycerate mutase	K15633 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]
D      Natgr_1696 D-3-phosphoglycerate dehydrogenase	K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
D      Natgr_3368 lactate dehydrogenase-like oxidoreductase	K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
D      Natgr_1427 phosphoserine phosphatase SerB	K01079 serB; phosphoserine phosphatase [EC:3.1.3.3]
D      Natgr_0788 monoamine oxidase	K00274 MAO; monoamine oxidase [EC:1.4.3.4]
D      Natgr_2870 glycine cleavage system protein P	K00282 gcvPA; glycine cleavage system P protein (glycine dehydrogenase) subunit 1 [EC:1.4.4.2]
D      Natgr_2871 glycine cleavage system protein P	K00283 gcvPB; glycine cleavage system P protein (glycine dehydrogenase) subunit 2 [EC:1.4.4.2]
D      Natgr_3023 glycine cleavage system T protein	K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]
D      Natgr_2446 folate-binding protein YgfZ	K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]
D      Natgr_1350 dihydrolipoamide dehydrogenase	K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D      Natgr_3022 glycine cleavage system H protein	K02437 gcvH; glycine cleavage system H protein
D      Natgr_1962 glycine/D-amino acid oxidase, deaminating	K00301 E1.5.3.1; sarcosine oxidase [EC:1.5.3.1]
D      Natgr_3575 cystathionine beta-lyase/cystathionine gamma-synthase	K01758 CTH; cystathionine gamma-lyase [EC:4.4.1.1]
D      Natgr_2150 cystathionine beta-lyase/cystathionine gamma-synthase	K01758 CTH; cystathionine gamma-lyase [EC:4.4.1.1]
D      Natgr_1639 threonine dehydratase, medium form	K01754 E4.3.1.19; threonine dehydratase [EC:4.3.1.19]
D      Natgr_2749 threonine dehydratase, medium form	K01754 E4.3.1.19; threonine dehydratase [EC:4.3.1.19]
D      Natgr_0762 tryptophan synthase, alpha subunit	K01695 trpA; tryptophan synthase alpha chain [EC:4.2.1.20]
D      Natgr_0763 tryptophan synthase, beta subunit	K01696 trpB; tryptophan synthase beta chain [EC:4.2.1.20]
D      Natgr_2704 tryptophan synthase, beta subunit	K01696 trpB; tryptophan synthase beta chain [EC:4.2.1.20]
C    00270 Cysteine and methionine metabolism [PATH:nge00270]
D      Natgr_1764 serine O-acetyltransferase	K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30]
D      Natgr_2905 serine acetyltransferase	K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30]
D      Natgr_0995 cysteine synthase A	K01738 cysK; cysteine synthase [EC:2.5.1.47]
D      Natgr_3352 cysteine synthase	K01738 cysK; cysteine synthase [EC:2.5.1.47]
D      Natgr_3575 cystathionine beta-lyase/cystathionine gamma-synthase	K01758 CTH; cystathionine gamma-lyase [EC:4.4.1.1]
D      Natgr_2150 cystathionine beta-lyase/cystathionine gamma-synthase	K01758 CTH; cystathionine gamma-lyase [EC:4.4.1.1]
D      Natgr_0629 cysteine synthase	K17216 mccA; cystathionine beta-synthase (O-acetyl-L-serine) [EC:2.5.1.134]
D      Natgr_2139 methionine synthase II (cobalamin-independent)	K00549 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14]
D      Natgr_2140 methionine synthase II (cobalamin-independent)	K00549 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14]
D      Natgr_0133 archaeal S-adenosylmethionine synthetase	K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]
D      Natgr_1782 cytosine deaminase-like metal-dependent hydrolase	K12960 mtaD; 5-methylthioadenosine/S-adenosylhomocysteine deaminase [EC:3.5.4.31 3.5.4.28]
D      Natgr_0495 cytosine deaminase-like metal-dependent hydrolase	K12960 mtaD; 5-methylthioadenosine/S-adenosylhomocysteine deaminase [EC:3.5.4.31 3.5.4.28]
D      Natgr_1501 cytosine deaminase-like metal-dependent hydrolase	K12960 mtaD; 5-methylthioadenosine/S-adenosylhomocysteine deaminase [EC:3.5.4.31 3.5.4.28]
D      Natgr_0166 DNA-methyltransferase Dcm	K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D      Natgr_2595 DNA-methyltransferase Dcm	K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D      Natgr_1780 adenosylhomocysteinase	K01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1]
D      Natgr_1590 aspartate kinase	K00928 lysC; aspartate kinase [EC:2.7.2.4]
D      Natgr_3787 aspartate-semialdehyde dehydrogenase	K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D      Natgr_0888 homoserine dehydrogenase	K00003 hom; homoserine dehydrogenase [EC:1.1.1.3]
D      Natgr_1425 homoserine O-acetyltransferase	K00641 metX; homoserine O-acetyltransferase/O-succinyltransferase [EC:2.3.1.31 2.3.1.46]
D      Natgr_1424 OAH/OAS sulfhydrylase	K01740 metY; O-acetylhomoserine (thiol)-lyase [EC:2.5.1.49]
D      Natgr_2686 OAH/OAS sulfhydrylase	K01740 metY; O-acetylhomoserine (thiol)-lyase [EC:2.5.1.49]
D      Natgr_0922 branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D      Natgr_2260 branched-chain amino acid aminotransferase, group I	K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D      Natgr_0871 aspartate/tyrosine/aromatic aminotransferase	K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D      Natgr_2941 aspartate/tyrosine/aromatic aminotransferase	K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D      Natgr_2037 aspartate/tyrosine/aromatic aminotransferase	K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D      Natgr_2191 rhodanese-related sulfurtransferase	K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]
D      Natgr_3159 rhodanese-related sulfurtransferase	K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]
D      Natgr_3655 rhodanese-related sulfurtransferase	K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]
D      Natgr_1710 malate/lactate dehydrogenase	K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D      Natgr_1696 D-3-phosphoglycerate dehydrogenase	K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
D      Natgr_3368 lactate dehydrogenase-like oxidoreductase	K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
C    00280 Valine, leucine and isoleucine degradation [PATH:nge00280]
D      Natgr_0922 branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D      Natgr_2260 branched-chain amino acid aminotransferase, group I	K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D      Natgr_3353 glutamate dehydrogenase/leucine dehydrogenase	K00263 E1.4.1.9; leucine dehydrogenase [EC:1.4.1.9]
D      Natgr_1350 dihydrolipoamide dehydrogenase	K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D      Natgr_0502 acyl-CoA dehydrogenase	K00249 ACADM; acyl-CoA dehydrogenase [EC:1.3.8.7]
D      Natgr_1273 acetyl-CoA acetyltransferase	K00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16]
D      Natgr_0598 acetyl/propionyl-CoA carboxylase, alpha subunit	K11263 bccA; acetyl-CoA/propionyl-CoA carboxylase, biotin carboxylase, biotin carboxyl carrier protein [EC:6.4.1.2 6.4.1.3 6.3.4.14]
D      Natgr_0600 acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	K19312 pccB; acetyl-CoA/propionyl-CoA carboxylase carboxyl transferase subunit [EC:6.4.1.2 6.4.1.3 2.1.3.15]
D      Natgr_0599 hypothetical protein	K22568 pccX; acetyl-CoA/propionyl-CoA carboxylase, PccX subunit [EC:6.4.1.2 6.4.1.3]
D      Natgr_3119 methylmalonyl-CoA epimerase	K05606 MCEE; methylmalonyl-CoA/ethylmalonyl-CoA epimerase [EC:5.1.99.1]
D      Natgr_0827 methylmalonyl-CoA mutase family protein	K01849 E5.4.99.2B; methylmalonyl-CoA mutase, C-terminal domain [EC:5.4.99.2]
D      Natgr_1584 methylmalonyl-CoA mutase family protein	K01848 E5.4.99.2A; methylmalonyl-CoA mutase, N-terminal domain [EC:5.4.99.2]
D      Natgr_3115 methylmalonyl-CoA mutase family protein	K01848 E5.4.99.2A; methylmalonyl-CoA mutase, N-terminal domain [EC:5.4.99.2]
D      Natgr_2669 NAD-dependent aldehyde dehydrogenase	K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D      Natgr_2311 NAD-dependent aldehyde dehydrogenase	K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D      Natgr_0823 acetyl-CoA acetyltransferase	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      Natgr_0426 acetyl-CoA acetyltransferase	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      Natgr_1255 acetyl-CoA acetyltransferase	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      Natgr_3067 acetyl-CoA acetyltransferase	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      Natgr_3496 acetyl-CoA acetyltransferase	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      Natgr_1254 3-hydroxy-3-methylglutaryl CoA synthase	K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10]
D      Natgr_2866 3-hydroxy-3-methylglutaryl CoA synthase	K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10]
C    00290 Valine, leucine and isoleucine biosynthesis [PATH:nge00290]
D      Natgr_1639 threonine dehydratase, medium form	K01754 E4.3.1.19; threonine dehydratase [EC:4.3.1.19]
D      Natgr_2749 threonine dehydratase, medium form	K01754 E4.3.1.19; threonine dehydratase [EC:4.3.1.19]
D      Natgr_0336 isopropylmalate/homocitrate/citramalate synthase	K09011 cimA; (R)-citramalate synthase [EC:2.3.3.21]
D      Natgr_0083 3-isopropylmalate dehydratase, large subunit	K01703 leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]
D      Natgr_0084 3-isopropylmalate dehydratase, small subunit	K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35]
D      Natgr_0087 isocitrate/isopropylmalate dehydrogenase	K00052 leuB; 3-isopropylmalate dehydrogenase [EC:1.1.1.85]
D      Natgr_0896 thiamine pyrophosphate-dependent enzyme, possible carboligase or decarboxylase	K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D      Natgr_0079 acetolactate synthase, large subunit, biosynthetic type	K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D      Natgr_1250 thiamine pyrophosphate-dependent enzyme, possible carboligase or decarboxylase	K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D      Natgr_0080 acetolactate synthase, small subunit	K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6]
D      Natgr_0081 ketol-acid reductoisomerase	K00053 ilvC; ketol-acid reductoisomerase [EC:1.1.1.86]
D      Natgr_0414 dihydroxy-acid dehydratase	K01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9]
D      Natgr_0922 branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D      Natgr_2260 branched-chain amino acid aminotransferase, group I	K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D      Natgr_3353 glutamate dehydrogenase/leucine dehydrogenase	K00263 E1.4.1.9; leucine dehydrogenase [EC:1.4.1.9]
D      Natgr_0078 isopropylmalate/homocitrate/citramalate synthase	K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13]
C    00300 Lysine biosynthesis [PATH:nge00300]
D      Natgr_0888 homoserine dehydrogenase	K00003 hom; homoserine dehydrogenase [EC:1.1.1.3]
D      Natgr_1590 aspartate kinase	K00928 lysC; aspartate kinase [EC:2.7.2.4]
D      Natgr_3787 aspartate-semialdehyde dehydrogenase	K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D      Natgr_0979 dihydrodipicolinate synthase	K01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7]
D      Natgr_2722 dihydrodipicolinate synthase/N-acetylneuraminate lyase	K01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7]
D      Natgr_0980 dihydrodipicolinate reductase	K00215 dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8]
D      Natgr_0981 tetrahydrodipicolinate N-succinyltransferase	K00674 dapD; 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [EC:2.3.1.117]
D      Natgr_3041 acetylornithine deacetylase/succinyldiaminopimelate desuccinylase-like deacylase	K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18]
D      Natgr_0988 acetylornithine deacetylase/succinyldiaminopimelate desuccinylase-like deacylase	K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18]
D      Natgr_0986 diaminopimelate decarboxylase	K01586 lysA; diaminopimelate decarboxylase [EC:4.1.1.20]
D      Natgr_1611 lysine biosynthesis protein LysW	K05826 lysW; alpha-aminoadipate/glutamate carrier protein LysW
D      Natgr_1614 acetylglutamate kinase	K05828 lysZ; [amino group carrier protein]-L-2-aminoadipate/L-glutamate 6-kinase [EC:2.7.2.17 2.7.2.19]
D      Natgr_1613 N-acetyl-gamma-glutamyl-phosphate reductase, common form	K05829 lysY; [amino group carrier protein]-6-phospho-L-2-aminoadipate/5-phospho-L-glutamate reductase [EC:1.2.1.103 1.2.1.106]
D      Natgr_1615 ornithine/acetylornithine aminotransferase	K05830 lysJ; [amino-group carrier protein]-gamma-(L-lysyl/L-ornithyl)-L-glutamate aminotransferase [EC:2.6.1.118 2.6.1.124]
D      Natgr_1616 N-acetyl-ornithine/N-acetyl-lysine deacetylase	K05831 lysK; [amino group carrier protein]-lysine/ornithine hydrolase [EC:3.5.1.130 3.5.1.132]
C    00310 Lysine degradation [PATH:nge00310]
D      Natgr_1350 dihydrolipoamide dehydrogenase	K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D      Natgr_1167 acyl-CoA dehydrogenase	K00252 GCDH; glutaryl-CoA dehydrogenase [EC:1.3.8.6]
D      Natgr_0823 acetyl-CoA acetyltransferase	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      Natgr_0426 acetyl-CoA acetyltransferase	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      Natgr_1255 acetyl-CoA acetyltransferase	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      Natgr_3067 acetyl-CoA acetyltransferase	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      Natgr_3496 acetyl-CoA acetyltransferase	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      Natgr_0438 NAD-dependent aldehyde dehydrogenase	K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
D      Natgr_2669 NAD-dependent aldehyde dehydrogenase	K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D      Natgr_2311 NAD-dependent aldehyde dehydrogenase	K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
C    00220 Arginine biosynthesis [PATH:nge00220]
D      Natgr_0689 ornithine carbamoyltransferase	K00611 OTC; ornithine carbamoyltransferase [EC:2.1.3.3]
D      Natgr_1609 argininosuccinate synthase	K01940 argG; argininosuccinate synthase [EC:6.3.4.5]
D      Natgr_1610 argininosuccinate lyase	K01755 argH; argininosuccinate lyase [EC:4.3.2.1]
D      Natgr_0687 arginine deiminase	K01478 arcA; arginine deiminase [EC:3.5.3.6]
D      Natgr_2846 nitric oxide synthase, oxygenase domain protein	K00491 nos; nitric-oxide synthase, bacterial [EC:1.14.14.47]
D      Natgr_1085 phosphoribosylformylglycinamidine synthase I	K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2]
D      Natgr_2338 glutamine synthetase	K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D      Natgr_3111 glutamine synthetase, type I	K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D      Natgr_0577 glutamate dehydrogenase/leucine dehydrogenase	K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]
D      Natgr_2884 glutamate dehydrogenase/leucine dehydrogenase	K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]
D      Natgr_0688 carbamate kinase	K00926 arcC; carbamate kinase [EC:2.7.2.2]
D      Natgr_0871 aspartate/tyrosine/aromatic aminotransferase	K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D      Natgr_2941 aspartate/tyrosine/aromatic aminotransferase	K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D      Natgr_2037 aspartate/tyrosine/aromatic aminotransferase	K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D      Natgr_0717 acetylornithine deacetylase/succinyldiaminopimelate desuccinylase-like deacylase	K01438 argE; acetylornithine deacetylase [EC:3.5.1.16]
D      Natgr_2321 acetylornithine deacetylase/succinyldiaminopimelate desuccinylase-like deacylase	K01438 argE; acetylornithine deacetylase [EC:3.5.1.16]
D      Natgr_1611 lysine biosynthesis protein LysW	K05826 lysW; alpha-aminoadipate/glutamate carrier protein LysW
D      Natgr_1612 Lysine biosynthesis enzyme LysX	K19412 argX; glutamate---[amino group carrier protein] ligase [EC:6.3.2.60]
D      Natgr_1614 acetylglutamate kinase	K05828 lysZ; [amino group carrier protein]-L-2-aminoadipate/L-glutamate 6-kinase [EC:2.7.2.17 2.7.2.19]
D      Natgr_1613 N-acetyl-gamma-glutamyl-phosphate reductase, common form	K05829 lysY; [amino group carrier protein]-6-phospho-L-2-aminoadipate/5-phospho-L-glutamate reductase [EC:1.2.1.103 1.2.1.106]
D      Natgr_1615 ornithine/acetylornithine aminotransferase	K05830 lysJ; [amino-group carrier protein]-gamma-(L-lysyl/L-ornithyl)-L-glutamate aminotransferase [EC:2.6.1.118 2.6.1.124]
D      Natgr_1616 N-acetyl-ornithine/N-acetyl-lysine deacetylase	K05831 lysK; [amino group carrier protein]-lysine/ornithine hydrolase [EC:3.5.1.130 3.5.1.132]
C    00330 Arginine and proline metabolism [PATH:nge00330]
D      Natgr_0585 uncharacterized protein, putative amidase	K01470 E3.5.2.10; creatinine amidohydrolase [EC:3.5.2.10]
D      Natgr_1315 uncharacterized protein, putative amidase	K01470 E3.5.2.10; creatinine amidohydrolase [EC:3.5.2.10]
D      Natgr_2290 N-methylhydantoinase A/acetone carboxylase, beta subunit	K01473 hyuA; N-methylhydantoinase A [EC:3.5.2.14]
D      Natgr_2291 N-methylhydantoinase B/acetone carboxylase, alpha subunit	K01474 hyuB; N-methylhydantoinase B [EC:3.5.2.14]
D      Natgr_1971 hypothetical protein	K02626 pdaD; arginine decarboxylase [EC:4.1.1.19]
D      Natgr_3213 agmatinase	K01480 speB; agmatinase [EC:3.5.3.11]
D      Natgr_2669 NAD-dependent aldehyde dehydrogenase	K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D      Natgr_2311 NAD-dependent aldehyde dehydrogenase	K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D      Natgr_0788 monoamine oxidase	K00274 MAO; monoamine oxidase [EC:1.4.3.4]
D      Natgr_3164 putative acetamidase/formamidase	K01426 E3.5.1.4; amidase [EC:3.5.1.4]
D      Natgr_3616 amidase, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit	K01426 E3.5.1.4; amidase [EC:3.5.1.4]
D      Natgr_2846 nitric oxide synthase, oxygenase domain protein	K00491 nos; nitric-oxide synthase, bacterial [EC:1.14.14.47]
D      Natgr_2467 pyrroline-5-carboxylate reductase	K00286 proC; pyrroline-5-carboxylate reductase [EC:1.5.1.2]
D      Natgr_1218 proline dehydrogenase	K00318 PRODH; proline dehydrogenase [EC:1.5.5.2]
D      Natgr_2462 proline dehydrogenase	K00318 PRODH; proline dehydrogenase [EC:1.5.5.2]
D      Natgr_2468 glutamate 5-kinase	K00931 proB; glutamate 5-kinase [EC:2.7.2.11]
D      Natgr_2469 gamma-glutamyl phosphate reductase	K00147 proA; glutamate-5-semialdehyde dehydrogenase [EC:1.2.1.41]
D      Natgr_0871 aspartate/tyrosine/aromatic aminotransferase	K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D      Natgr_2941 aspartate/tyrosine/aromatic aminotransferase	K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D      Natgr_2037 aspartate/tyrosine/aromatic aminotransferase	K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
C    00340 Histidine metabolism [PATH:nge00340]
D      Natgr_1795 ATP phosphoribosyltransferase	K00765 hisG; ATP phosphoribosyltransferase [EC:2.4.2.17]
D      Natgr_2024 phosphoribosyl-ATP pyrophosphohydrolase	K01523 hisE; phosphoribosyl-ATP pyrophosphohydrolase [EC:3.6.1.31]
D      Natgr_1692 phosphoribosyl-AMP cyclohydrolase	K01496 hisI; phosphoribosyl-AMP cyclohydrolase [EC:3.5.4.19]
D      Natgr_1752 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase	K01814 hisA; phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase [EC:5.3.1.16]
D      Natgr_2346 imidazole glycerol phosphate synthase, glutamine amidotransferase subunit	K02501 hisH; imidazole glycerol-phosphate synthase subunit HisH [EC:4.3.2.10]
D      Natgr_0052 imidazoleglycerol phosphate synthase, cyclase subunit	K02500 hisF; imidazole glycerol-phosphate synthase subunit HisF [EC:4.3.2.10]
D      Natgr_1422 imidazoleglycerol-phosphate dehydratase	K01693 hisB; imidazoleglycerol-phosphate dehydratase [EC:4.2.1.19]
D      Natgr_3600 histidinol-phosphate aminotransferase	K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D      Natgr_3716 PHP family phosphohydrolase, histidinol phosphatase	K04486 E3.1.3.15B; histidinol-phosphatase (PHP family) [EC:3.1.3.15]
D      Natgr_3798 histidinol dehydrogenase	K00013 hisD; histidinol dehydrogenase [EC:1.1.1.23]
D      Natgr_0126 histidine ammonia-lyase	K01745 hutH; histidine ammonia-lyase [EC:4.3.1.3]
D      Natgr_0129 urocanate hydratase	K01712 hutU; urocanate hydratase [EC:4.2.1.49]
D      Natgr_0127 imidazolonepropionase	K01468 hutI; imidazolonepropionase [EC:3.5.2.7]
D      Natgr_2669 NAD-dependent aldehyde dehydrogenase	K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D      Natgr_2311 NAD-dependent aldehyde dehydrogenase	K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D      Natgr_0788 monoamine oxidase	K00274 MAO; monoamine oxidase [EC:1.4.3.4]
C    00350 Tyrosine metabolism [PATH:nge00350]
D      Natgr_0871 aspartate/tyrosine/aromatic aminotransferase	K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D      Natgr_2941 aspartate/tyrosine/aromatic aminotransferase	K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D      Natgr_2037 aspartate/tyrosine/aromatic aminotransferase	K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D      Natgr_3600 histidinol-phosphate aminotransferase	K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D      Natgr_3048 tyrosine decarboxylase MnfA	K18933 mfnA; tyrosine decarboxylase / aspartate 1-decarboxylase [EC:4.1.1.25 4.1.1.11]
D      Natgr_0788 monoamine oxidase	K00274 MAO; monoamine oxidase [EC:1.4.3.4]
D      Natgr_0438 NAD-dependent aldehyde dehydrogenase	K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
C    00360 Phenylalanine metabolism [PATH:nge00360]
D      Natgr_0788 monoamine oxidase	K00274 MAO; monoamine oxidase [EC:1.4.3.4]
D      Natgr_1236 coenzyme F390 synthetase	K01912 paaK; phenylacetate-CoA ligase [EC:6.2.1.30]
D      Natgr_1242 phenylacetic acid degradation protein PaaD	K02614 paaI; acyl-CoA thioesterase [EC:3.1.2.-]
D      Natgr_1244 hypothetical protein	K02609 paaA; ring-1,2-phenylacetyl-CoA epoxidase subunit PaaA [EC:1.14.13.149]
D      Natgr_1245 putative enzyme of phenylacetate metabolism	K02610 paaB; ring-1,2-phenylacetyl-CoA epoxidase subunit PaaB
D      Natgr_1246 phenylacetate-CoA oxygenase, PaaI subunit	K02611 paaC; ring-1,2-phenylacetyl-CoA epoxidase subunit PaaC [EC:1.14.13.149]
D      Natgr_1580 enoyl-CoA hydratase/carnithine racemase	K15866 paaG; 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA isomerase [EC:5.3.3.18]
D      Natgr_1257 3-hydroxyacyl-CoA dehydrogenase	K00074 paaH; 3-hydroxybutyryl-CoA dehydrogenase [EC:1.1.1.157]
D      Natgr_1582 3-hydroxyacyl-CoA dehydrogenase	K00074 paaH; 3-hydroxybutyryl-CoA dehydrogenase [EC:1.1.1.157]
D      Natgr_0871 aspartate/tyrosine/aromatic aminotransferase	K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D      Natgr_2941 aspartate/tyrosine/aromatic aminotransferase	K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D      Natgr_2037 aspartate/tyrosine/aromatic aminotransferase	K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D      Natgr_3600 histidinol-phosphate aminotransferase	K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D      Natgr_0484 catalase/peroxidase HPI	K03782 katG; catalase-peroxidase [EC:1.11.1.21]
D      Natgr_3164 putative acetamidase/formamidase	K01426 E3.5.1.4; amidase [EC:3.5.1.4]
D      Natgr_3616 amidase, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit	K01426 E3.5.1.4; amidase [EC:3.5.1.4]
C    00380 Tryptophan metabolism [PATH:nge00380]
D      Natgr_1350 dihydrolipoamide dehydrogenase	K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D      Natgr_1167 acyl-CoA dehydrogenase	K00252 GCDH; glutaryl-CoA dehydrogenase [EC:1.3.8.6]
D      Natgr_0823 acetyl-CoA acetyltransferase	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      Natgr_0426 acetyl-CoA acetyltransferase	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      Natgr_1255 acetyl-CoA acetyltransferase	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      Natgr_3067 acetyl-CoA acetyltransferase	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      Natgr_3496 acetyl-CoA acetyltransferase	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      Natgr_1589 tryptophanase	K01667 tnaA; tryptophanase [EC:4.1.99.1]
D      Natgr_0788 monoamine oxidase	K00274 MAO; monoamine oxidase [EC:1.4.3.4]
D      Natgr_2669 NAD-dependent aldehyde dehydrogenase	K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D      Natgr_2311 NAD-dependent aldehyde dehydrogenase	K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D      Natgr_3164 putative acetamidase/formamidase	K01426 E3.5.1.4; amidase [EC:3.5.1.4]
D      Natgr_3616 amidase, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit	K01426 E3.5.1.4; amidase [EC:3.5.1.4]
D      Natgr_0484 catalase/peroxidase HPI	K03782 katG; catalase-peroxidase [EC:1.11.1.21]
C    00400 Phenylalanine, tyrosine and tryptophan biosynthesis [PATH:nge00400]
D      Natgr_0761 putative phospho-2-dehydro-3-deoxyheptonate aldolase	K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10]
D      Natgr_1033 putative alternative 3-dehydroquinate synthase	K11646 K11646; 3-dehydroquinate synthase II [EC:1.4.1.24]
D      Natgr_1039 3-dehydroquinate dehydratase	K03785 aroD; 3-dehydroquinate dehydratase I [EC:4.2.1.10]
D      Natgr_0948 shikimate 5-dehydrogenase	K00014 aroE; shikimate dehydrogenase [EC:1.1.1.25]
D      Natgr_3564 shikimate kinase	K00891 aroK; shikimate kinase [EC:2.7.1.71]
D      Natgr_3721 3-phosphoshikimate 1-carboxyvinyltransferase	K00800 aroA; 3-phosphoshikimate 1-carboxyvinyltransferase [EC:2.5.1.19]
D      Natgr_3719 chorismate synthase	K01736 aroC; chorismate synthase [EC:4.2.3.5]
D      Natgr_0946 aminodeoxychorismate synthase, component I, clade 2	K01657 trpE; anthranilate synthase component I [EC:4.1.3.27]
D      Natgr_3762 anthranilate synthase component I, archaeal clade	K01657 trpE; anthranilate synthase component I [EC:4.1.3.27]
D      Natgr_0945 glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase	K01658 trpG; anthranilate synthase component II [EC:4.1.3.27]
D      Natgr_3763 glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase	K01658 trpG; anthranilate synthase component II [EC:4.1.3.27]
D      Natgr_3760 anthranilate phosphoribosyltransferase	K00766 trpD; anthranilate phosphoribosyltransferase [EC:2.4.2.18]
D      Natgr_3761 phosphoribosylanthranilate isomerase	K01817 trpF; phosphoribosylanthranilate isomerase [EC:5.3.1.24]
D      Natgr_0764 Indole-3-glycerol phosphate synthase	K01609 trpC; indole-3-glycerol phosphate synthase [EC:4.1.1.48]
D      Natgr_0762 tryptophan synthase, alpha subunit	K01695 trpA; tryptophan synthase alpha chain [EC:4.2.1.20]
D      Natgr_0763 tryptophan synthase, beta subunit	K01696 trpB; tryptophan synthase beta chain [EC:4.2.1.20]
D      Natgr_2704 tryptophan synthase, beta subunit	K01696 trpB; tryptophan synthase beta chain [EC:4.2.1.20]
D      Natgr_3563 chorismate mutase	K04093 pheA1; chorismate mutase [EC:5.4.99.5]
D      Natgr_0227 prephenate dehydrogenase	K04517 tyrA2; prephenate dehydrogenase [EC:1.3.1.12]
D      Natgr_1390 prephenate dehydratase	K04518 pheA2; prephenate dehydratase [EC:4.2.1.51]
D      Natgr_0871 aspartate/tyrosine/aromatic aminotransferase	K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D      Natgr_2941 aspartate/tyrosine/aromatic aminotransferase	K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D      Natgr_2037 aspartate/tyrosine/aromatic aminotransferase	K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D      Natgr_3600 histidinol-phosphate aminotransferase	K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
B
B  09106 Metabolism of other amino acids
C    00410 beta-Alanine metabolism [PATH:nge00410]
D      Natgr_3048 tyrosine decarboxylase MnfA	K18933 mfnA; tyrosine decarboxylase / aspartate 1-decarboxylase [EC:4.1.1.25 4.1.1.11]
D      Natgr_3371 4-aminobutyrate aminotransferase family protein	K00823 puuE; 4-aminobutyrate aminotransferase [EC:2.6.1.19]
D      Natgr_2669 NAD-dependent aldehyde dehydrogenase	K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D      Natgr_2311 NAD-dependent aldehyde dehydrogenase	K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D      Natgr_2091 hypothetical protein	K09722 K09722; 4-phosphopantoate---beta-alanine ligase [EC:6.3.2.36]
D      Natgr_0462 amidase, hydantoinase/carbamoylase family	K06016 pydC; beta-ureidopropionase / N-carbamoyl-L-amino-acid hydrolase [EC:3.5.1.6 3.5.1.87]
C    00430 Taurine and hypotaurine metabolism [PATH:nge00430]
D      Natgr_3671 gamma-glutamyltransferase	K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
D      Natgr_3775 gamma-glutamyltransferase	K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
D      Natgr_1735 putative ornithine cyclodeaminase, mu-crystallin	K19244 ala; alanine dehydrogenase [EC:1.4.1.1]
C    00440 Phosphonate and phosphinate metabolism
D      Natgr_2310 metal-dependent hydrolase, beta-lactamase superfamily I	K06167 phnP; phosphoribosyl 1,2-cyclic phosphate phosphodiesterase [EC:3.1.4.55]
C    00450 Selenocompound metabolism [PATH:nge00450]
D      Natgr_2139 methionine synthase II (cobalamin-independent)	K00549 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14]
D      Natgr_2140 methionine synthase II (cobalamin-independent)	K00549 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14]
D      Natgr_3575 cystathionine beta-lyase/cystathionine gamma-synthase	K01758 CTH; cystathionine gamma-lyase [EC:4.4.1.1]
D      Natgr_2150 cystathionine beta-lyase/cystathionine gamma-synthase	K01758 CTH; cystathionine gamma-lyase [EC:4.4.1.1]
D      Natgr_1522 cysteine desulfurase-like protein, SufS subfamily	K11717 sufS; cysteine desulfurase / selenocysteine lyase [EC:2.8.1.7 4.4.1.16]
D      Natgr_0643 thioredoxin reductase	K00384 trxB; thioredoxin reductase (NADPH) [EC:1.8.1.9]
D      Natgr_3154 thioredoxin reductase	K00384 trxB; thioredoxin reductase (NADPH) [EC:1.8.1.9]
D      Natgr_3698 Glutaredoxin, GrxC family	K00384 trxB; thioredoxin reductase (NADPH) [EC:1.8.1.9]
D      Natgr_0816 thioredoxin reductase	K00384 trxB; thioredoxin reductase (NADPH) [EC:1.8.1.9]
D      Natgr_1560 thioredoxin reductase	K00384 trxB; thioredoxin reductase (NADPH) [EC:1.8.1.9]
D      Natgr_0647 methionyl-tRNA synthetase	K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
C    00460 Cyanoamino acid metabolism [PATH:nge00460]
D      Natgr_3671 gamma-glutamyltransferase	K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
D      Natgr_3775 gamma-glutamyltransferase	K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
D      Natgr_1117 asparaginase	K13051 ASRGL1; L-asparaginase / beta-aspartyl-peptidase [EC:3.5.1.1 3.4.19.5]
D      Natgr_3637 glycine/serine hydroxymethyltransferase	K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
C    00470 D-Amino acid metabolism [PATH:nge00470]
D      Natgr_1085 phosphoribosylformylglycinamidine synthase I	K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2]
D      Natgr_0747 hypothetical protein	K26272 dgcN; D-glutamate N-acetyltransferase [EC:2.3.1.312]
D      Natgr_0748 enolase superfamily enzyme related to L-alanine-DL-glutamate epimerase	K19802 ycjG; L-Ala-D/L-Glu epimerase / N-acetyl-D-glutamate racemase [EC:5.1.1.20 5.1.1.25]
D      Natgr_0986 diaminopimelate decarboxylase	K01586 lysA; diaminopimelate decarboxylase [EC:4.1.1.20]
C    00480 Glutathione metabolism [PATH:nge00480]
D      Natgr_3671 gamma-glutamyltransferase	K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
D      Natgr_3775 gamma-glutamyltransferase	K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
D      Natgr_0185 carboxylate-amine ligase, YbdK family	K06048 gshA; glutamate---cysteine ligase / carboxylate-amine ligase [EC:6.3.2.2 6.3.-.-]
D      Natgr_1115 isocitrate dehydrogenase, NADP-dependent, prokaryotic type	K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]
D      Natgr_2304 6-phosphogluconate dehydrogenase, decarboxylating	K00033 PGD; 6-phosphogluconate dehydrogenase [EC:1.1.1.44 1.1.1.343]
B
B  09107 Glycan biosynthesis and metabolism
C    00510 N-Glycan biosynthesis
C    00513 Various types of N-glycan biosynthesis
C    00512 Mucin type O-glycan biosynthesis
C    00515 Mannose type O-glycan biosynthesis
C    00514 Other types of O-glycan biosynthesis
C    00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate
C    00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin
C    00533 Glycosaminoglycan biosynthesis - keratan sulfate
C    00531 Glycosaminoglycan degradation
C    00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
C    00601 Glycosphingolipid biosynthesis - lacto and neolacto series
C    00603 Glycosphingolipid biosynthesis - globo and isoglobo series
C    00604 Glycosphingolipid biosynthesis - ganglio series
C    00511 Other glycan degradation
C    00540 Lipopolysaccharide biosynthesis
C    00542 O-Antigen repeat unit biosynthesis
C    00541 O-Antigen nucleotide sugar biosynthesis
C    00550 Peptidoglycan biosynthesis
C    00552 Teichoic acid biosynthesis
C    00571 Lipoarabinomannan (LAM) biosynthesis
C    00572 Arabinogalactan biosynthesis - Mycobacterium
C    00543 Exopolysaccharide biosynthesis [PATH:nge00543]
D      Natgr_1764 serine O-acetyltransferase	K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30]
D      Natgr_2905 serine acetyltransferase	K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30]
B
B  09108 Metabolism of cofactors and vitamins
C    00730 Thiamine metabolism [PATH:nge00730]
D      Natgr_3056 thiamine biosynthesis protein ThiC	K03147 thiC; phosphomethylpyrimidine synthase [EC:4.1.99.17]
D      Natgr_2394 phosphomethylpyrimidine kinase	K21219 thiDN; hydroxymethylpyrimidine kinase / phosphomethylpyrimidine kinase / thiamine-phosphate diphosphorylase [EC:2.7.1.49 2.7.4.7 2.5.1.3]
D      Natgr_0131 thiamine biosynthesis ATP pyrophosphatase	K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]
D      Natgr_0926 thiazole biosynthesis enzyme	K22699 thi4; sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59]
D      Natgr_1545 hydroxyethylthiazole kinase, sugar kinase family	K00878 thiM; hydroxyethylthiazole kinase [EC:2.7.1.50]
D      Natgr_1544 thiamine-phosphate pyrophosphorylase	K00788 thiE; thiamine-phosphate pyrophosphorylase [EC:2.5.1.3]
D      Natgr_2423 thiamine-monophosphate kinase	K00946 thiL; thiamine-monophosphate kinase [EC:2.7.4.16]
D      Natgr_0140 adenylate kinase family protein	K00939 adk; adenylate kinase [EC:2.7.4.3]
D      Natgr_2811 putative transcription activator	K03707 tenA; thiaminase (transcriptional activator TenA) [EC:3.5.99.2]
C    00740 Riboflavin metabolism [PATH:nge00740]
D      Natgr_3410 hypothetical protein	K08096 gch3; GTP cyclohydrolase IIa [EC:3.5.4.29]
D      Natgr_2807 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 1'-reductase	K14654 RIB7; 2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase [EC:1.1.1.302]
D      Natgr_3244 haloacid dehalogenase superfamily enzyme, subfamily IA	K20862 yigB; FMN hydrolase / 5-amino-6-(5-phospho-D-ribitylamino)uracil phosphatase [EC:3.1.3.102 3.1.3.104]
D      Natgr_2257 3,4-dihydroxy-2-butanone 4-phosphate synthase	K02858 ribB; 3,4-dihydroxy 2-butanone 4-phosphate synthase [EC:4.1.99.12]
D      Natgr_0870 6,7-dimethyl-8-ribityllumazine synthase	K00794 ribH; 6,7-dimethyl-8-ribityllumazine synthase [EC:2.5.1.78]
D      Natgr_1159 riboflavin synthase, alpha subunit	K00793 ribE; riboflavin synthase [EC:2.5.1.9]
D      Natgr_2256 transcriptional regulator of a riboflavin/FAD biosynthetic operon	K07732 rfk; riboflavin kinase, archaea type [EC:2.7.1.161]
D      Natgr_0418 cytidyltransferase-related enzyme	K14656 ribL; FAD synthetase [EC:2.7.7.2]
D      Natgr_1545 hydroxyethylthiazole kinase, sugar kinase family	K00878 thiM; hydroxyethylthiazole kinase [EC:2.7.1.50]
D      Natgr_1058 NTP pyrophosphohydrolase	K01515 nudF; ADP-ribose diphosphatase [EC:3.6.1.13 3.6.1.-]
D      Natgr_1905 ADP-ribose pyrophosphatase	K01515 nudF; ADP-ribose diphosphatase [EC:3.6.1.13 3.6.1.-]
C    00750 Vitamin B6 metabolism [PATH:nge00750]
D      Natgr_1620 threonine synthase	K01733 thrC; threonine synthase [EC:4.2.3.1]
D      Natgr_2082 threonine synthase	K01733 thrC; threonine synthase [EC:4.2.3.1]
D      Natgr_1998 threonine synthase	K01733 thrC; threonine synthase [EC:4.2.3.1]
D      Natgr_2336 threonine synthase	K01733 thrC; threonine synthase [EC:4.2.3.1]
D      Natgr_2130 pyridoxal 5'-phosphate synthase, synthase subunit Pdx1	K06215 pdxS; pyridoxal 5'-phosphate synthase pdxS subunit [EC:4.3.3.6]
D      Natgr_2022 pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2	K08681 pdxT; pyridoxal 5'-phosphate synthase pdxT subunit [EC:4.3.3.6]
C    00760 Nicotinate and nicotinamide metabolism [PATH:nge00760]
D      Natgr_1145 aspartate oxidase	K00278 nadB; L-aspartate oxidase [EC:1.4.3.16]
D      Natgr_1144 quinolinate synthetase complex, A subunit	K03517 nadA; quinolinate synthase [EC:2.5.1.72]
D      Natgr_1146 nicotinate-nucleotide pyrophosphorylase	K00767 nadC; nicotinate-nucleotide pyrophosphorylase (carboxylating) [EC:2.4.2.19]
D      Natgr_1283 nicotinic acid phosphoribosyltransferase	K00763 pncB; nicotinate phosphoribosyltransferase [EC:6.3.4.21]
D      Natgr_0839 5'/3'-nucleotidase SurE	K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6]
D      Natgr_0229 5'/3'-nucleotidase SurE	K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6]
D      Natgr_0769 nicotinamide-nucleotide adenylyltransferase	K00952 nadM; nicotinamide-nucleotide adenylyltransferase [EC:2.7.7.1]
D      Natgr_1651 NAD+ synthetase	K01916 nadE; NAD+ synthase [EC:6.3.1.5]
D      Natgr_2036 competence/damage-inducible protein CinA-like protein	K03743 pncC; nicotinamide-nucleotide amidase [EC:3.5.1.42]
D      Natgr_2085 NAD-dependent protein deacetylase, SIR2 family	K12410 cobB; NAD-dependent protein deacetylase/lipoamidase [EC:2.3.1.286 2.3.1.313]
D      Natgr_0451 putative sugar kinase	K00858 ppnK; NAD+ kinase [EC:2.7.1.23]
D      Natgr_1194 putative sugar kinase	K00858 ppnK; NAD+ kinase [EC:2.7.1.23]
D      Natgr_2292 maleate cis-trans isomerase	K01799 nicE; maleate isomerase [EC:5.2.1.1]
D      Natgr_0438 NAD-dependent aldehyde dehydrogenase	K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
C    00770 Pantothenate and CoA biosynthesis [PATH:nge00770]
D      Natgr_0896 thiamine pyrophosphate-dependent enzyme, possible carboligase or decarboxylase	K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D      Natgr_0079 acetolactate synthase, large subunit, biosynthetic type	K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D      Natgr_1250 thiamine pyrophosphate-dependent enzyme, possible carboligase or decarboxylase	K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D      Natgr_0080 acetolactate synthase, small subunit	K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6]
D      Natgr_0081 ketol-acid reductoisomerase	K00053 ilvC; ketol-acid reductoisomerase [EC:1.1.1.86]
D      Natgr_0414 dihydroxy-acid dehydratase	K01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9]
D      Natgr_3027 3-methyl-2-oxobutanoate hydroxymethyltransferase	K00606 panB; 3-methyl-2-oxobutanoate hydroxymethyltransferase [EC:2.1.2.11]
D      Natgr_1450 2-dehydropantoate 2-reductase	K00077 panE; 2-dehydropantoate 2-reductase [EC:1.1.1.169]
D      Natgr_2089 putative kinase, sugar kinase superfamily	K06982 pok; pantoate kinase [EC:2.7.1.169]
D      Natgr_2091 hypothetical protein	K09722 K09722; 4-phosphopantoate---beta-alanine ligase [EC:6.3.2.36]
D      Natgr_0814 phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase	K13038 coaBC; phosphopantothenoylcysteine decarboxylase / phosphopantothenate---cysteine ligase [EC:4.1.1.36 6.3.2.5]
D      Natgr_0697 cytidyltransferase-related enzyme	K02201 E2.7.7.3B; pantetheine-phosphate adenylyltransferase [EC:2.7.7.3]
D      Natgr_0357 cytidyltransferase-related enzyme	K02201 E2.7.7.3B; pantetheine-phosphate adenylyltransferase [EC:2.7.7.3]
D      Natgr_2317 hypothetical protein	K09735 dpck; GTP-dependent dephospho-CoA kinase [EC:2.7.1.237]
D      Natgr_0922 branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D      Natgr_2260 branched-chain amino acid aminotransferase, group I	K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D      Natgr_0462 amidase, hydantoinase/carbamoylase family	K06016 pydC; beta-ureidopropionase / N-carbamoyl-L-amino-acid hydrolase [EC:3.5.1.6 3.5.1.87]
D      Natgr_3048 tyrosine decarboxylase MnfA	K18933 mfnA; tyrosine decarboxylase / aspartate 1-decarboxylase [EC:4.1.1.25 4.1.1.11]
D      Natgr_2669 NAD-dependent aldehyde dehydrogenase	K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D      Natgr_2311 NAD-dependent aldehyde dehydrogenase	K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
C    00780 Biotin metabolism [PATH:nge00780]
D      Natgr_0372 dehydrogenase of unknown specificity, short-chain alcohol dehydrogenase like protein	K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D      Natgr_0427 dehydrogenase of unknown specificity, short-chain alcohol dehydrogenase like protein	K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D      Natgr_3259 dehydrogenase of unknown specificity, short-chain alcohol dehydrogenase like protein	K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D      Natgr_0594 dehydrogenase of unknown specificity, short-chain alcohol dehydrogenase like protein	K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D      Natgr_2199 short-chain alcohol dehydrogenase	K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D      Natgr_2205 7-keto-8-aminopelargonate synthetase-like enzyme	K00652 bioF; 8-amino-7-oxononanoate synthase [EC:2.3.1.47]
D      Natgr_3684 7-keto-8-aminopelargonate synthetase-like enzyme	K00652 bioF; 8-amino-7-oxononanoate synthase [EC:2.3.1.47]
D      Natgr_2206 dethiobiotin synthase	K01935 bioD; dethiobiotin synthetase [EC:6.3.3.3]
D      Natgr_2204 hypothetical protein	K25570 bioU; 8-amino-7-oxononanoate carboxylating dehydrogenase [EC:2.6.1.121]
D      Natgr_2203 biotin synthase	K01012 bioB; biotin synthase [EC:2.8.1.6]
D      Natgr_2213 birA, biotin-(acetyl-CoA-carboxylase) ligase	K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]
C    00785 Lipoic acid metabolism [PATH:nge00785]
D      Natgr_1354 lipoate synthase	K03644 lipA; lipoyl synthase [EC:2.8.1.8]
D      Natgr_1275 lipoate-protein ligase A	K16869 lipL; octanoyl-[GcvH]:protein N-octanoyltransferase [EC:2.3.1.204]
D      Natgr_2496 lipoate-protein ligase A	K03800 lplA; lipoate---protein ligase [EC:6.3.1.20]
D      Natgr_1350 dihydrolipoamide dehydrogenase	K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D      Natgr_1353 pyruvate dehydrogenase E1 component, alpha subunit	K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
D      Natgr_1352 pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase component beta subunit	K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
D      Natgr_1351 pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase component	K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
D      Natgr_2870 glycine cleavage system protein P	K00282 gcvPA; glycine cleavage system P protein (glycine dehydrogenase) subunit 1 [EC:1.4.4.2]
D      Natgr_2871 glycine cleavage system protein P	K00283 gcvPB; glycine cleavage system P protein (glycine dehydrogenase) subunit 2 [EC:1.4.4.2]
D      Natgr_3023 glycine cleavage system T protein	K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]
D      Natgr_2446 folate-binding protein YgfZ	K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]
D      Natgr_3022 glycine cleavage system H protein	K02437 gcvH; glycine cleavage system H protein
C    00790 Folate biosynthesis [PATH:nge00790]
D      Natgr_0004 dihydropteroate synthase	K00796 folP; dihydropteroate synthase [EC:2.5.1.15]
D      Natgr_3609 dihydropteroate synthase	K24102 folCP; dihydrofolate synthase / dihydropteroate synthase [EC:6.3.2.12 2.5.1.15]
D      Natgr_3360 dihydrofolate reductase	K00287 DHFR; dihydrofolate reductase [EC:1.5.1.3]
D      Natgr_0609 6-pyruvoyl-tetrahydropterin synthase	K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]
D      Natgr_3299 6-pyruvoyl-tetrahydropterin synthase	K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]
D      Natgr_3195 pterin-4a-carbinolamine dehydratase	K01724 PCBD; 4a-hydroxytetrahydrobiopterin dehydratase [EC:4.2.1.96]
D      Natgr_0608 organic radical activating enzyme	K10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3]
D      Natgr_0607 queuosine biosynthesis protein QueC	K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20]
D      Natgr_1192 TIGR00294 family protein	K17488 mptA; GTP cyclohydrolase IV [EC:3.5.4.39]
D      Natgr_1319 hypothetical protein	K09739 mptD; dihydroneopterin aldolase [EC:4.1.2.25]
D      Natgr_0005 uncharacterized Rossmann fold enzyme	K07142 mptE; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase [EC:2.7.6.3]
D      Natgr_0402 beta-RFAP synthase	K06984 K06984; beta-ribofuranosylaminobenzene 5'-phosphate synthase [EC:2.4.2.54]
D      Natgr_2706 putative molybdenum cofactor biosynthesis protein A, archaeal	K03639 moaA; GTP 3',8-cyclase [EC:4.1.99.22]
D      Natgr_0373 molybdenum cofactor biosynthesis protein MoaC	K03637 moaC; cyclic pyranopterin monophosphate synthase [EC:4.6.1.17]
D      Natgr_2420 molybdopterin converting factor, large subunit	K03635 MOCS2B; molybdopterin synthase catalytic subunit [EC:2.8.1.12]
D      Natgr_1004 molybdopterin biosynthesis enzyme	K03638 moaB; molybdopterin adenylyltransferase [EC:2.7.7.75]
D      Natgr_1300 molybdenum cofactor synthesis domain protein	K03638 moaB; molybdopterin adenylyltransferase [EC:2.7.7.75]
D      Natgr_3199 molybdenum cofactor synthesis domain protein	K03750 moeA; molybdopterin molybdotransferase [EC:2.10.1.1]
D      Natgr_3207 molybdenum cofactor synthesis domain protein	K03750 moeA; molybdopterin molybdotransferase [EC:2.10.1.1]
D      Natgr_0404 molybdopterin-guanine dinucleotide biosynthesis protein A	K03752 mobA; molybdenum cofactor guanylyltransferase [EC:2.7.7.77]
C    00670 One carbon pool by folate [PATH:nge00670]
D      Natgr_3360 dihydrofolate reductase	K00287 DHFR; dihydrofolate reductase [EC:1.5.1.3]
D      Natgr_0650 formyltetrahydrofolate synthetase	K01938 fhs; formate--tetrahydrofolate ligase [EC:6.3.4.3]
D      Natgr_2920 formyltetrahydrofolate synthetase	K01938 fhs; formate--tetrahydrofolate ligase [EC:6.3.4.3]
D      Natgr_3636 5,10-methylene-tetrahydrofolate dehydrogenase/methenyl tetrahydrofolate cyclohydrolase	K01491 folD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9]
D      Natgr_3637 glycine/serine hydroxymethyltransferase	K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D      Natgr_0994 AICAR transformylase/IMP cyclohydrolase PurH	K01492 purNH; phosphoribosylglycinamide/phosphoribosylaminoimidazolecarboxamide formyltransferase [EC:2.1.2.2 2.1.2.3]
D      Natgr_2414 methionyl-tRNA formyltransferase	K00604 MTFMT; methionyl-tRNA formyltransferase [EC:2.1.2.9]
D      Natgr_3023 glycine cleavage system T protein	K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]
D      Natgr_2446 folate-binding protein YgfZ	K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]
D      Natgr_3361 thymidylate synthase	K00560 thyA; thymidylate synthase [EC:2.1.1.45]
D      Natgr_2906 5,10-methylenetetrahydrofolate reductase	K00297 metF; methylenetetrahydrofolate reductase (NADH) [EC:1.5.1.54]
D      Natgr_1005 5-formyltetrahydrofolate cyclo-ligase	K01934 MTHFS; 5-formyltetrahydrofolate cyclo-ligase [EC:6.3.3.2]
C    00830 Retinol metabolism
C    00860 Porphyrin metabolism [PATH:nge00860]
D      Natgr_2571 glutamyl-tRNA synthetase, archaeal and eukaryotic family	K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D      Natgr_3194 glutamyl-tRNA reductase	K02492 hemA; glutamyl-tRNA reductase [EC:1.2.1.70]
D      Natgr_1461 glutamate-1-semialdehyde aminotransferase	K01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8]
D      Natgr_1463 delta-aminolevulinic acid dehydratase	K01698 hemB; porphobilinogen synthase [EC:4.2.1.24]
D      Natgr_1458 porphobilinogen deaminase	K01749 hemC; hydroxymethylbilane synthase [EC:2.5.1.61]
D      Natgr_1457 uroporphyrinogen-III synthase	K01719 hemD; uroporphyrinogen-III synthase [EC:4.2.1.75]
D      Natgr_3137 uroporphyrinogen decarboxylase	K01599 hemE; uroporphyrinogen decarboxylase [EC:4.1.1.37]
D      Natgr_0465 protoporphyrinogen oxidase	K00231 PPOX; protoporphyrinogen/coproporphyrinogen III oxidase [EC:1.3.3.4 1.3.3.15]
D      Natgr_3138 ferrochelatase	K01772 hemH; protoporphyrin/coproporphyrin ferrochelatase [EC:4.98.1.1 4.99.1.9]
D      Natgr_2412 hypothetical protein	K25033 chdC; hydrogen peroxide-dependent heme synthase [EC:1.3.98.5]
D      Natgr_0101 uroporphyrin-III C-methyltransferase	K02303 cobA; uroporphyrin-III C-methyltransferase [EC:2.1.1.107]
D      Natgr_0102 siroheme synthase, N-terminal domain protein	K24866 sirC; precorrin-2 dehydrogenase [EC:1.3.1.76]
D      Natgr_2129 putative Fe-S oxidoreductase	K22227 ahbD; AdoMet-dependent heme synthase [EC:1.3.98.6]
D      Natgr_0675 protoheme IX farnesyltransferase	K02257 COX10; heme o synthase [EC:2.5.1.141]
D      Natgr_0392 uncharacterized protein required for cytochrome oxidase assembly	K02259 COX15; heme a synthase [EC:1.17.99.9]
D      Natgr_0111 hypothetical protein	K03795 cbiX; sirohydrochlorin cobaltochelatase [EC:4.99.1.3]
D      Natgr_0104 precorrin-2 methylase	K03394 cobI-cbiL; precorrin-2/cobalt-factor-2 C20-methyltransferase [EC:2.1.1.130 2.1.1.151]
D      Natgr_0107 precorrin-3B methylase	K05934 cobJ; precorrin-3B C17-methyltransferase / cobalt-factor III methyltransferase [EC:2.1.1.131 2.1.1.272]
D      Natgr_0105 precorrin-4 methylase	K05936 cobM; precorrin-4/cobalt-precorrin-4 C11-methyltransferase [EC:2.1.1.133 2.1.1.271]
D      Natgr_0106 cobalamin biosynthesis protein CbiG	K02189 cbiG; cobalt-precorrin 5A hydrolase [EC:3.7.1.12]
D      Natgr_0103 precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit	K02191 cbiT; cobalt-precorrin-6B (C15)-methyltransferase [EC:2.1.1.196]
D      Natgr_0118 precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit	K03399 cbiE; cobalt-precorrin-7 (C5)-methyltransferase [EC:2.1.1.289]
D      Natgr_0117 precorrin isomerase	K06042 cobH-cbiC; precorrin-8X/cobalt-precorrin-8 methylmutase [EC:5.4.99.61 5.4.99.60]
D      Natgr_0537 cobyrinic acid a,c-diamide synthase	K02224 cobB-cbiA; cobyrinic acid a,c-diamide synthase [EC:6.3.5.9 6.3.5.11]
D      Natgr_0116 cobaltochelatase, CobN subunit	K02230 cobN; cobaltochelatase CobN [EC:6.6.1.2]
D      Natgr_2873 ATP:cob(I)alamin adenosyltransferase	K00798 MMAB; cob(I)alamin adenosyltransferase [EC:2.5.1.17]
D      Natgr_0120 ATP:corrinoid adenosyltransferase	K19221 cobA; cob(I)alamin adenosyltransferase [EC:2.5.1.17]
D      Natgr_0122 cobyric acid synthase CobQ	K02232 cobQ; adenosylcobyric acid synthase [EC:6.3.5.10]
D      Natgr_2761 cobalamin biosynthesis protein CobD	K02227 cbiB; adenosylcobinamide-phosphate synthase [EC:6.3.1.10]
D      Natgr_2766 hypothetical protein	K08260 cbiZ; adenosylcobinamide hydrolase [EC:3.5.1.90]
D      Natgr_2763 GTP:adenosylcobinamide-phosphate guanylyltransferase	K19712 cobY; adenosylcobinamide-phosphate guanylyltransferase [EC:2.7.7.62]
D      Natgr_2762 cobalamin 5''-phosphate synthase/cobalamin synthase	K02233 E2.7.8.26; adenosylcobinamide-GDP ribazoletransferase [EC:2.7.8.26]
D      Natgr_2765 L-threonine-O-3-phosphate decarboxylase	K04720 cobD; threonine-phosphate decarboxylase [EC:4.1.1.81]
D      Natgr_0115 Mg-chelatase subunit ChlI	K03404 chlD; magnesium chelatase subunit D [EC:6.6.1.1]
C    00130 Ubiquinone and other terpenoid-quinone biosynthesis [PATH:nge00130]
D      Natgr_0062 isochorismate synthase family protein	K02552 menF; menaquinone-specific isochorismate synthase [EC:5.4.4.2]
D      Natgr_0063 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase	K02551 menD; 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase [EC:2.2.1.9]
D      Natgr_0211 enolase superfamily enzyme related to L-alanine-DL-glutamate epimerase	K02549 menC; o-succinylbenzoate synthase [EC:4.2.1.113]
D      Natgr_0212 acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	K01911 menE; o-succinylbenzoate---CoA ligase [EC:6.2.1.26]
D      Natgr_0067 dihydroxynaphthoate synthase	K01661 menB; naphthoate synthase [EC:4.1.3.36]
D      Natgr_0210 1,4-dihydroxy-2-naphthoate octaprenyltransferase	K02548 menA; 1,4-dihydroxy-2-naphthoate polyprenyltransferase [EC:2.5.1.74]
B
B  09109 Metabolism of terpenoids and polyketides
C    00900 Terpenoid backbone biosynthesis [PATH:nge00900]
D      Natgr_0823 acetyl-CoA acetyltransferase	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      Natgr_0426 acetyl-CoA acetyltransferase	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      Natgr_1255 acetyl-CoA acetyltransferase	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      Natgr_3067 acetyl-CoA acetyltransferase	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      Natgr_3496 acetyl-CoA acetyltransferase	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      Natgr_1254 3-hydroxy-3-methylglutaryl CoA synthase	K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10]
D      Natgr_2866 3-hydroxy-3-methylglutaryl CoA synthase	K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10]
D      Natgr_1105 NADP-dependent hydroxymethylglutaryl-CoA reductase	K00021 HMGCR; hydroxymethylglutaryl-CoA reductase (NADPH) [EC:1.1.1.34]
D      Natgr_2565 mevalonate kinase	K00869 MVK; mevalonate kinase [EC:2.7.1.36]
D      Natgr_0456 mevalonate pyrophosphate decarboxylase	K17942 pmd; phosphomevalonate decarboxylase [EC:4.1.1.99]
D      Natgr_2566 putative archaeal kinase	K06981 ipk; isopentenyl phosphate kinase [EC:2.7.4.26]
D      Natgr_1000 isopentenyldiphosphate isomerase	K01823 idi; isopentenyl-diphosphate Delta-isomerase [EC:5.3.3.2]
D      Natgr_1571 isopentenyl-diphosphate delta-isomerase, type 2	K01823 idi; isopentenyl-diphosphate Delta-isomerase [EC:5.3.3.2]
D      Natgr_0449 geranylgeranyl pyrophosphate synthase	K13787 idsA; geranylgeranyl diphosphate synthase, type I [EC:2.5.1.1 2.5.1.10 2.5.1.29]
D      Natgr_1989 geranylgeranyl pyrophosphate synthase	K13787 idsA; geranylgeranyl diphosphate synthase, type I [EC:2.5.1.1 2.5.1.10 2.5.1.29]
D      Natgr_2570 geranylgeranyl pyrophosphate synthase	K13787 idsA; geranylgeranyl diphosphate synthase, type I [EC:2.5.1.1 2.5.1.10 2.5.1.29]
D      Natgr_3190 undecaprenyl pyrophosphate synthase	K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31]
D      Natgr_3192 undecaprenyl diphosphate synthase	K15888 uppS; tritrans,polycis-undecaprenyl-diphosphate synthase [geranylgeranyl-diphosphate specific] [EC:2.5.1.89]
C    00902 Monoterpenoid biosynthesis
C    00909 Sesquiterpenoid and triterpenoid biosynthesis [PATH:nge00909]
D      Natgr_0050 phytoene/squalene synthetase	K00801 FDFT1; farnesyl-diphosphate farnesyltransferase [EC:2.5.1.21]
C    00904 Diterpenoid biosynthesis
C    00906 Carotenoid biosynthesis [PATH:nge00906]
D      Natgr_2207 phytoene/squalene synthetase	K02291 crtB; 15-cis-phytoene synthase [EC:2.5.1.32]
D      Natgr_2201 4-hydroxybenzoate polyprenyltransferase-like prenyltransferase	K20616 lyeJ; lycopene elongase/hydratase (dihydrobisanhydrobacterioruberin-forming) [EC:2.5.1.150]
D      Natgr_2200 phytoene desaturase	K20611 crtD; 1-hydroxy-2-isopentenylcarotenoid 3,4-desaturase [EC:1.3.99.37]
D      Natgr_2202 carotene biosynthesis associated membrane protein	K08977 cruF; bisanhydrobacterioruberin hydratase [EC:4.2.1.161]
D      Natgr_0245 lycopene cyclase domain protein	K22502 crtY; lycopene beta-cyclase [EC:5.5.1.19]
D      Natgr_3013 lycopene cyclase domain protein	K22502 crtY; lycopene beta-cyclase [EC:5.5.1.19]
C    00905 Brassinosteroid biosynthesis
C    00981 Insect hormone biosynthesis
C    00908 Zeatin biosynthesis
C    00903 Limonene degradation
C    00907 Pinene, camphor and geraniol degradation [PATH:nge00907]
D      Natgr_1273 acetyl-CoA acetyltransferase	K00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16]
C    01052 Type I polyketide structures
C    00522 Biosynthesis of 12-, 14- and 16-membered macrolides
C    01051 Biosynthesis of ansamycins
C    01059 Biosynthesis of enediyne antibiotics
C    01056 Biosynthesis of type II polyketide backbone
C    01057 Biosynthesis of type II polyketide products
C    00253 Tetracycline biosynthesis
C    00523 Polyketide sugar unit biosynthesis
D      Natgr_0914 Nucleoside-diphosphate-sugar pyrophosphorylase family protein	K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D      Natgr_2894 Nucleoside-diphosphate-sugar pyrophosphorylase family protein	K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D      Natgr_2230 dTDP-glucose pyrophosphorylase	K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D      Natgr_3335 UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase	K23144 K23144; UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.7.7.24 2.7.7.83 2.3.1.157 2.3.1.276]
C    01054 Nonribosomal peptide structures
C    01053 Biosynthesis of siderophore group nonribosomal peptides
D      Natgr_0062 isochorismate synthase family protein	K02552 menF; menaquinone-specific isochorismate synthase [EC:5.4.4.2]
C    01055 Biosynthesis of vancomycin group antibiotics
B
B  09110 Biosynthesis of other secondary metabolites
C    00940 Phenylpropanoid biosynthesis
C    00945 Stilbenoid, diarylheptanoid and gingerol biosynthesis
C    00941 Flavonoid biosynthesis
C    00944 Flavone and flavonol biosynthesis
C    00942 Anthocyanin biosynthesis
C    00943 Isoflavonoid biosynthesis
C    00946 Degradation of flavonoids
C    00901 Indole alkaloid biosynthesis
C    00403 Indole diterpene alkaloid biosynthesis
C    00950 Isoquinoline alkaloid biosynthesis
C    00960 Tropane, piperidine and pyridine alkaloid biosynthesis
C    00996 Biosynthesis of various alkaloids
C    00232 Caffeine metabolism
C    00965 Betalain biosynthesis
C    00966 Glucosinolate biosynthesis
C    00402 Benzoxazinoid biosynthesis
C    00311 Penicillin and cephalosporin biosynthesis
D      Natgr_2814 penicilin amidase	K01434 pac; penicillin G amidase [EC:3.5.1.11]
C    00332 Carbapenem biosynthesis [PATH:nge00332]
D      Natgr_2468 glutamate 5-kinase	K00931 proB; glutamate 5-kinase [EC:2.7.2.11]
D      Natgr_2469 gamma-glutamyl phosphate reductase	K00147 proA; glutamate-5-semialdehyde dehydrogenase [EC:1.2.1.41]
C    00261 Monobactam biosynthesis [PATH:nge00261]
D      Natgr_1590 aspartate kinase	K00928 lysC; aspartate kinase [EC:2.7.2.4]
D      Natgr_3787 aspartate-semialdehyde dehydrogenase	K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D      Natgr_0979 dihydrodipicolinate synthase	K01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7]
D      Natgr_2722 dihydrodipicolinate synthase/N-acetylneuraminate lyase	K01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7]
D      Natgr_0980 dihydrodipicolinate reductase	K00215 dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8]
C    00331 Clavulanic acid biosynthesis
C    00521 Streptomycin biosynthesis [PATH:nge00521]
D      Natgr_0459 transcriptional regulator/sugar kinase	K25026 glk; glucokinase [EC:2.7.1.2]
D      Natgr_1689 phosphoglucosamine mutase	K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D      Natgr_0330 inositol monophosphatase/fructose-1,6-bisphosphatase family protein	K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25]
D      Natgr_0202 inositol monophosphatase/fructose-1,6-bisphosphatase family protein	K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25]
D      Natgr_1371 inositol monophosphatase/fructose-1,6-bisphosphatase family protein	K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25]
D      Natgr_0914 Nucleoside-diphosphate-sugar pyrophosphorylase family protein	K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D      Natgr_2894 Nucleoside-diphosphate-sugar pyrophosphorylase family protein	K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D      Natgr_2230 dTDP-glucose pyrophosphorylase	K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D      Natgr_3335 UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase	K23144 K23144; UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.7.7.24 2.7.7.83 2.3.1.157 2.3.1.276]
C    00524 Neomycin, kanamycin and gentamicin biosynthesis
D      Natgr_0459 transcriptional regulator/sugar kinase	K25026 glk; glucokinase [EC:2.7.1.2]
C    00525 Acarbose and validamycin biosynthesis
D      Natgr_0914 Nucleoside-diphosphate-sugar pyrophosphorylase family protein	K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D      Natgr_2894 Nucleoside-diphosphate-sugar pyrophosphorylase family protein	K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D      Natgr_2230 dTDP-glucose pyrophosphorylase	K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D      Natgr_3335 UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase	K23144 K23144; UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.7.7.24 2.7.7.83 2.3.1.157 2.3.1.276]
C    00401 Novobiocin biosynthesis [PATH:nge00401]
D      Natgr_0227 prephenate dehydrogenase	K04517 tyrA2; prephenate dehydrogenase [EC:1.3.1.12]
D      Natgr_0871 aspartate/tyrosine/aromatic aminotransferase	K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D      Natgr_2941 aspartate/tyrosine/aromatic aminotransferase	K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D      Natgr_2037 aspartate/tyrosine/aromatic aminotransferase	K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D      Natgr_3600 histidinol-phosphate aminotransferase	K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
C    00404 Staurosporine biosynthesis
C    00405 Phenazine biosynthesis
D      Natgr_0946 aminodeoxychorismate synthase, component I, clade 2	K01657 trpE; anthranilate synthase component I [EC:4.1.3.27]
D      Natgr_3762 anthranilate synthase component I, archaeal clade	K01657 trpE; anthranilate synthase component I [EC:4.1.3.27]
D      Natgr_0945 glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase	K01658 trpG; anthranilate synthase component II [EC:4.1.3.27]
D      Natgr_3763 glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase	K01658 trpG; anthranilate synthase component II [EC:4.1.3.27]
C    00333 Prodigiosin biosynthesis
D      Natgr_0372 dehydrogenase of unknown specificity, short-chain alcohol dehydrogenase like protein	K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D      Natgr_0427 dehydrogenase of unknown specificity, short-chain alcohol dehydrogenase like protein	K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D      Natgr_3259 dehydrogenase of unknown specificity, short-chain alcohol dehydrogenase like protein	K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D      Natgr_0594 dehydrogenase of unknown specificity, short-chain alcohol dehydrogenase like protein	K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D      Natgr_2199 short-chain alcohol dehydrogenase	K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
C    00254 Aflatoxin biosynthesis
C    00998 Biosynthesis of various antibiotics
C    00999 Biosynthesis of various plant secondary metabolites [PATH:nge00999]
D      Natgr_0133 archaeal S-adenosylmethionine synthetase	K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]
D      Natgr_0948 shikimate 5-dehydrogenase	K00014 aroE; shikimate dehydrogenase [EC:1.1.1.25]
C    00997 Biosynthesis of various other secondary metabolites
B
B  09111 Xenobiotics biodegradation and metabolism
C    00362 Benzoate degradation [PATH:nge00362]
D      Natgr_1630 putative hydrolase or acyltransferase of alpha/beta superfamily	K01055 pcaD; 3-oxoadipate enol-lactonase [EC:3.1.1.24]
D      Natgr_1273 acetyl-CoA acetyltransferase	K00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16]
D      Natgr_1167 acyl-CoA dehydrogenase	K00252 GCDH; glutaryl-CoA dehydrogenase [EC:1.3.8.6]
D      Natgr_1257 3-hydroxyacyl-CoA dehydrogenase	K00074 paaH; 3-hydroxybutyryl-CoA dehydrogenase [EC:1.1.1.157]
D      Natgr_1582 3-hydroxyacyl-CoA dehydrogenase	K00074 paaH; 3-hydroxybutyryl-CoA dehydrogenase [EC:1.1.1.157]
D      Natgr_0823 acetyl-CoA acetyltransferase	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      Natgr_0426 acetyl-CoA acetyltransferase	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      Natgr_1255 acetyl-CoA acetyltransferase	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      Natgr_3067 acetyl-CoA acetyltransferase	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      Natgr_3496 acetyl-CoA acetyltransferase	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
C    00627 Aminobenzoate degradation [PATH:nge00627]
D      Natgr_3164 putative acetamidase/formamidase	K01426 E3.5.1.4; amidase [EC:3.5.1.4]
D      Natgr_3616 amidase, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit	K01426 E3.5.1.4; amidase [EC:3.5.1.4]
D      Natgr_0377 acylphosphatase	K01512 acyP; acylphosphatase [EC:3.6.1.7]
C    00364 Fluorobenzoate degradation
C    00625 Chloroalkane and chloroalkene degradation [PATH:nge00625]
D      Natgr_2669 NAD-dependent aldehyde dehydrogenase	K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D      Natgr_2311 NAD-dependent aldehyde dehydrogenase	K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
C    00361 Chlorocyclohexane and chlorobenzene degradation
C    00623 Toluene degradation
C    00622 Xylene degradation
C    00633 Nitrotoluene degradation [PATH:nge00633]
D      Natgr_2158 Ni,Fe-hydrogenase I small subunit	K06282 hyaA; hydrogenase small subunit [EC:1.12.99.6]
D      Natgr_2159 Ni,Fe-hydrogenase I large subunit	K23549 hupV; uptake hydrogenase large subunit [EC:1.12.99.6]
D      Natgr_3239 2-oxoacid:acceptor oxidoreductase, alpha subunit	K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D      Natgr_3238 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate family	K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
C    00642 Ethylbenzene degradation
D      Natgr_1273 acetyl-CoA acetyltransferase	K00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16]
C    00643 Styrene degradation [PATH:nge00643]
D      Natgr_3164 putative acetamidase/formamidase	K01426 E3.5.1.4; amidase [EC:3.5.1.4]
D      Natgr_3616 amidase, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit	K01426 E3.5.1.4; amidase [EC:3.5.1.4]
C    00791 Atrazine degradation
C    00930 Caprolactam degradation
C    00363 Bisphenol degradation
C    00621 Dioxin degradation
C    00626 Naphthalene degradation
C    00624 Polycyclic aromatic hydrocarbon degradation
C    00365 Furfural degradation
C    00984 Steroid degradation
C    00980 Metabolism of xenobiotics by cytochrome P450
C    00982 Drug metabolism - cytochrome P450
C    00983 Drug metabolism - other enzymes
B
B  09112 Not included in regular maps
C    09113 Global maps only
#
A09120 Genetic Information Processing
B
B  09121 Transcription
C    03020 RNA polymerase [PATH:nge03020]
D      Natgr_1200 DNA-directed RNA polymerase subunit B	K03044 rpoB1; DNA-directed RNA polymerase subunit B' [EC:2.7.7.6]
D      Natgr_1199 DNA-directed RNA polymerase, beta subunit/140 kD subunit	K03045 rpoB2; DNA-directed RNA polymerase subunit B" [EC:2.7.7.6]
D      Natgr_1201 DNA-directed RNA polymerase subunit A''	K03041 rpoA1; DNA-directed RNA polymerase subunit A' [EC:2.7.7.6]
D      Natgr_1202 DNA-directed RNA polymerase, subunit A''''	K03042 rpoA2; DNA-directed RNA polymerase subunit A" [EC:2.7.7.6]
D      Natgr_2554 DNA-directed RNA polymerase, alpha subunit/40 kD subunit	K03047 rpoD; DNA-directed RNA polymerase subunit D [EC:2.7.7.6]
D      Natgr_0049 DNA-directed RNA polymerase, subunit L	K03056 rpoL; DNA-directed RNA polymerase subunit L [EC:2.7.7.6]
D      Natgr_2315 DNA-directed RNA polymerase subunit E'	K03049 rpoE1; DNA-directed RNA polymerase subunit E' [EC:2.7.7.6]
D      Natgr_2148 hypothetical protein	K03051 rpoF; DNA-directed RNA polymerase subunit F [EC:2.7.7.6]
D      Natgr_1198 DNA-directed RNA polymerase, subunit H, RpoH/RPB5	K03053 rpoH; DNA-directed RNA polymerase subunit H [EC:2.7.7.6]
D      Natgr_2560 DNA-directed RNA polymerase, subunit K/omega	K03055 rpoK; DNA-directed RNA polymerase subunit K [EC:2.7.7.6]
D      Natgr_2559 DNA-directed RNA polymerase, subunit N (RpoN/RPB10)	K03058 rpoN; DNA-directed RNA polymerase subunit N [EC:2.7.7.6]
D      Natgr_0844 DNA-directed RNA polymerase, subunit RPC10 (contains C4-type Zn-finger)	K03059 rpoP; DNA-directed RNA polymerase subunit P [EC:2.7.7.6]
C    03022 Basal transcription factors [PATH:nge03022]
D      Natgr_0435 transcription initiation factor TFIIIB, Brf1 subunit/transcription initiation factor TFIIB	K03124 TFIIB; transcription initiation factor TFIIB
D      Natgr_1038 transcription initiation factor TFIIIB, Brf1 subunit/transcription initiation factor TFIIB	K03124 TFIIB; transcription initiation factor TFIIB
D      Natgr_0385 transcription initiation factor TFIIIB, Brf1 subunit/transcription initiation factor TFIIB	K03124 TFIIB; transcription initiation factor TFIIB
D      Natgr_0220 transcription initiation factor TFIIIB, Brf1 subunit/transcription initiation factor TFIIB	K03124 TFIIB; transcription initiation factor TFIIB
D      Natgr_1737 transcription initiation factor TFIIIB, Brf1 subunit/transcription initiation factor TFIIB	K03124 TFIIB; transcription initiation factor TFIIB
D      Natgr_2650 hypothetical protein	K03124 TFIIB; transcription initiation factor TFIIB
D      Natgr_2544 transcription initiation factor TFIIIB, Brf1 subunit/transcription initiation factor TFIIB	K03124 TFIIB; transcription initiation factor TFIIB
D      Natgr_3557 transcription initiation factor TFIIIB, Brf1 subunit/transcription initiation factor TFIIB	K03124 TFIIB; transcription initiation factor TFIIB
D      Natgr_1799 TATA-box binding protein (TBP), component of TFIID and TFIIIB	K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
D      Natgr_1810 TATA-box binding protein (TBP), component of TFIID and TFIIIB	K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
D      Natgr_3245 TATA-box binding protein (TBP), component of TFIID and TFIIIB	K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
D      Natgr_0521 TIGR00373 family protein	K03136 TFIIE1; transcription initiation factor TFIIE subunit alpha
D      Natgr_3560 DNA/RNA helicase, superfamily II	K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
D      Natgr_1604 DNA helicase, Rad3	K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
D      Natgr_1641 DNA helicase, Rad3	K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
C    03040 Spliceosome
B
B  09122 Translation
C    03010 Ribosome [PATH:nge03010]
D      Natgr_2562 ribosomal protein Sa/S2	K02967 RP-S2; small subunit ribosomal protein S2
D      Natgr_0309 ribosomal protein S3, eukaryotic/archaeal type	K02982 RP-S3; small subunit ribosomal protein S3
D      Natgr_2552 ribosomal protein S4/S9	K02986 RP-S4; small subunit ribosomal protein S4
D      Natgr_0295 ribosomal protein S5/S2	K02988 RP-S5; small subunit ribosomal protein S5
D      Natgr_1207 ribosomal protein S7/S5	K02992 RP-S7; small subunit ribosomal protein S7
D      Natgr_0300 ribosomal protein S8	K02994 RP-S8; small subunit ribosomal protein S8
D      Natgr_2558 archaeal ribosomal protein S9P	K02996 RP-S9; small subunit ribosomal protein S9
D      Natgr_0890 ribosomal protein S10/S20	K02946 RP-S10; small subunit ribosomal protein S10
D      Natgr_2553 archaeal ribosomal protein S11P	K02948 RP-S11; small subunit ribosomal protein S11
D      Natgr_1206 ribosomal protein S23	K02950 RP-S12; small subunit ribosomal protein S12
D      Natgr_2551 archaeal ribosomal protein S13P	K02952 RP-S13; small subunit ribosomal protein S13
D      Natgr_0301 ribosomal protein S14	K02954 RP-S14; small subunit ribosomal protein S14
D      Natgr_2115 ribosomal protein S14	K02954 RP-S14; small subunit ribosomal protein S14
D      Natgr_0943 ribosomal protein S15P/S13E	K02956 RP-S15; small subunit ribosomal protein S15
D      Natgr_0306 archaeal ribosomal protein S17P	K02961 RP-S17; small subunit ribosomal protein S17
D      Natgr_0311 ribosomal protein S19/S15	K02965 RP-S19; small subunit ribosomal protein S19
D      Natgr_0940 ribosomal protein S3AE	K02984 RP-S3Ae; small subunit ribosomal protein S3Ae
D      Natgr_0303 ribosomal protein S4E	K02987 RP-S4e; small subunit ribosomal protein S4e
D      Natgr_1925 ribosomal protein S6E (S10)	K02991 RP-S6e; small subunit ribosomal protein S6e
D      Natgr_0355 ribosomal protein S8.e	K02995 RP-S8e; small subunit ribosomal protein S8e
D      Natgr_3785 ribosomal protein S17E	K02962 RP-S17e; small subunit ribosomal protein S17e
D      Natgr_2424 ribosomal protein S19E (S16A)	K02966 RP-S19e; small subunit ribosomal protein S19e
D      Natgr_2110 ribosomal protein S24E	K02974 RP-S24e; small subunit ribosomal protein S24e
D      Natgr_0792 ribosomal protein S27E	K02978 RP-S27e; small subunit ribosomal protein S27e
D      Natgr_2109 ribosomal protein S27AE	K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae
D      Natgr_2580 ribosomal protein S28E/S33	K02979 RP-S28e; small subunit ribosomal protein S28e
D      Natgr_0239 ribosomal protein L1	K02863 RP-L1; large subunit ribosomal protein L1
D      Natgr_0312 ribosomal protein L2	K02886 RP-L2; large subunit ribosomal protein L2
D      Natgr_0315 archaeal ribosomal protein L3	K02906 RP-L3; large subunit ribosomal protein L3
D      Natgr_0302 ribosomal protein L5	K02931 RP-L5; large subunit ribosomal protein L5
D      Natgr_0299 archaeal ribosomal protein L6P	K02933 RP-L6; large subunit ribosomal protein L6
D      Natgr_0240 ribosomal protein L10	K02864 RP-L10; large subunit ribosomal protein L10
D      Natgr_2935 ribosomal protein L11	K02867 RP-L11; large subunit ribosomal protein L11
D      Natgr_0241 50S ribosomal protein L12P	K02869 RP-L12; large subunit ribosomal protein L12
D      Natgr_2557 ribosomal protein L13, archaeal/eukaryotic	K02871 RP-L13; large subunit ribosomal protein L13
D      Natgr_0305 50S ribosomal protein L14P	K02874 RP-L14; large subunit ribosomal protein L14
D      Natgr_0293 ribosomal protein L15	K02876 RP-L15; large subunit ribosomal protein L15
D      Natgr_0296 ribosomal protein L18	K02881 RP-L18; large subunit ribosomal protein L18
D      Natgr_0310 ribosomal protein L22/L17	K02890 RP-L22; large subunit ribosomal protein L22
D      Natgr_0313 archaeal ribosomal protein L23	K02892 RP-L23; large subunit ribosomal protein L23
D      Natgr_0304 ribosomal protein L24p/L26e, archaeal/eukaryotic	K02895 RP-L24; large subunit ribosomal protein L24
D      Natgr_0308 ribosomal protein L29	K02904 RP-L29; large subunit ribosomal protein L29
D      Natgr_0294 50S ribosomal protein L30P, archaeal	K02907 RP-L30; large subunit ribosomal protein L30
D      Natgr_0314 50S ribosomal protein L4P	K02930 RP-L4e; large subunit ribosomal protein L4e
D      Natgr_2579 50S ribosomal protein L7Ae	K02936 RP-L7Ae; large subunit ribosomal protein L7Ae
D      Natgr_1667 ribosomal protein L16/L10E	K02866 RP-L10e; large subunit ribosomal protein L10e
D      Natgr_2481 ribosomal protein L15E	K02877 RP-L15e; large subunit ribosomal protein L15e
D      Natgr_2556 ribosomal protein L18E	K02883 RP-L18e; large subunit ribosomal protein L18e
D      Natgr_0297 ribosomal protein L19E	K02885 RP-L19e; large subunit ribosomal protein L19e
D      Natgr_2149 ribosomal protein L21E	K02889 RP-L21e; large subunit ribosomal protein L21e
D      Natgr_1535 ribosomal protein L31E	K02910 RP-L31e; large subunit ribosomal protein L31e
D      Natgr_0298 ribosomal protein L32E	K02912 RP-L32e; large subunit ribosomal protein L32e
D      Natgr_2078 ribosomal protein L37E	K02922 RP-L37e; large subunit ribosomal protein L37e
D      Natgr_0843 ribosomal protein L37AE/L43A	K02921 RP-L37Ae; large subunit ribosomal protein L37Ae
D      Natgr_1534 ribosomal protein L39E	K02924 RP-L39e; large subunit ribosomal protein L39e
D      Natgr_1147 ribosomal protein L40E	K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e
D      Natgr_0793 ribosomal protein L44E	K02929 RP-L44e; large subunit ribosomal protein L44e
D      Natgr_1541 ribosomal protein L20A (L18A)	K02944 RP-LX; large subunit ribosomal protein LX
D      Natgr_1833 16S ribosomal RNA	K01977 16SrRNA; 16S ribosomal RNA
D      Natgr_1346 16S ribosomal RNA	K01977 16SrRNA; 16S ribosomal RNA
D      Natgr_3796 16S ribosomal RNA	K01977 16SrRNA; 16S ribosomal RNA
D      Natgr_3794 23S ribosomal RNA	K01980 23SrRNA; 23S ribosomal RNA
D      Natgr_1835 23S ribosomal RNA	K01980 23SrRNA; 23S ribosomal RNA
D      Natgr_1344 23S ribosomal RNA	K01980 23SrRNA; 23S ribosomal RNA
D      Natgr_1343 5S ribosomal RNA	K01985 5SrRNA; 5S ribosomal RNA
D      Natgr_3793 5S ribosomal RNA	K01985 5SrRNA; 5S ribosomal RNA
D      Natgr_1836 5S ribosomal RNA	K01985 5SrRNA; 5S ribosomal RNA
C    00970 Aminoacyl-tRNA biosynthesis [PATH:nge00970]
D      Natgr_1345 tRNA-Ala	K14218 tRNA-Ala; tRNA Ala
D      Natgr_3795 tRNA-Ala	K14218 tRNA-Ala; tRNA Ala
D      Natgr_1834 tRNA-Ala	K14218 tRNA-Ala; tRNA Ala
D      Natgr_0944 tRNA-Ala	K14218 tRNA-Ala; tRNA Ala
D      Natgr_0892 tRNA-Ala	K14218 tRNA-Ala; tRNA Ala
D      Natgr_0624 tRNA-Arg	K14219 tRNA-Arg; tRNA Arg
D      Natgr_0501 tRNA-Arg	K14219 tRNA-Arg; tRNA Arg
D      Natgr_1550 tRNA-Arg	K14219 tRNA-Arg; tRNA Arg
D      Natgr_1288 tRNA-Arg	K14219 tRNA-Arg; tRNA Arg
D      Natgr_1293 tRNA-Asn	K14220 tRNA-Asn; tRNA Asn
D      Natgr_1653 tRNA-Asp	K14221 tRNA-Asp; tRNA Asp
D      Natgr_1655 tRNA-Asp	K14221 tRNA-Asp; tRNA Asp
D      Natgr_1837 tRNA-Cys	K14222 tRNA-Cys; tRNA Cys
D      Natgr_0879 tRNA-Gln	K14223 tRNA-Gln; tRNA Gln
D      Natgr_1518 tRNA-Gln	K14223 tRNA-Gln; tRNA Gln
D      Natgr_2589 tRNA-Glu	K14224 tRNA-Glu; tRNA Glu
D      Natgr_3694 tRNA-Glu	K14224 tRNA-Glu; tRNA Glu
D      Natgr_1652 tRNA-Gly	K14225 tRNA-Gly; tRNA Gly
D      Natgr_3601 tRNA-Gly	K14225 tRNA-Gly; tRNA Gly
D      Natgr_0727 tRNA-Gly	K14225 tRNA-Gly; tRNA Gly
D      Natgr_1305 tRNA-His	K14226 tRNA-His; tRNA His
D      Natgr_1165 tRNA-Ile	K14227 tRNA-Ile; tRNA Ile
D      Natgr_0360 tRNA-Leu	K14228 tRNA-Leu; tRNA Leu
D      Natgr_2555 tRNA-Leu	K14228 tRNA-Leu; tRNA Leu
D      Natgr_0204 tRNA-Leu	K14228 tRNA-Leu; tRNA Leu
D      Natgr_2176 tRNA-Leu	K14228 tRNA-Leu; tRNA Leu
D      Natgr_1177 tRNA-Leu	K14228 tRNA-Leu; tRNA Leu
D      Natgr_1899 tRNA-Lys	K14229 tRNA-Lys; tRNA Lys
D      Natgr_3234 tRNA-Lys	K14229 tRNA-Lys; tRNA Lys
D      Natgr_1830 tRNA-Met	K14230 tRNA-Met; tRNA Met
D      Natgr_3772 tRNA-Met	K14230 tRNA-Met; tRNA Met
D      Natgr_0796 tRNA-Met	K14230 tRNA-Met; tRNA Met
D      Natgr_1309 tRNA-Phe	K14231 tRNA-Phe; tRNA Phe
D      Natgr_1029 tRNA-Pro	K14232 tRNA-Pro; tRNA Pro
D      Natgr_0147 tRNA-Pro	K14232 tRNA-Pro; tRNA Pro
D      Natgr_1741 tRNA-Pro	K14232 tRNA-Pro; tRNA Pro
D      Natgr_2550 tRNA-Ser	K14233 tRNA-Ser; tRNA Ser
D      Natgr_2331 tRNA-Ser	K14233 tRNA-Ser; tRNA Ser
D      Natgr_3382 tRNA-Ser	K14233 tRNA-Ser; tRNA Ser
D      Natgr_0715 tRNA-Ser	K14233 tRNA-Ser; tRNA Ser
D      Natgr_1646 tRNA-Thr	K14234 tRNA-Thr; tRNA Thr
D      Natgr_0099 tRNA-Thr	K14234 tRNA-Thr; tRNA Thr
D      Natgr_3269 tRNA-Trp	K14235 tRNA-Trp; tRNA Trp
D      Natgr_2509 tRNA-Tyr	K14236 tRNA-Tyr; tRNA Tyr
D      Natgr_3759 tRNA-Val	K14237 tRNA-Val; tRNA Val
D      Natgr_1311 tRNA-Val	K14237 tRNA-Val; tRNA Val
D      Natgr_2999 tRNA-Val	K14237 tRNA-Val; tRNA Val
D      Natgr_2571 glutamyl-tRNA synthetase, archaeal and eukaryotic family	K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D      Natgr_0218 glutamyl-tRNA(Gln) and/or aspartyl-tRNA(Asn) amidotransferase, A subunit	K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7]
D      Natgr_3674 glutamyl-tRNA(Gln) and/or aspartyl-tRNA(Asn) amidotransferase, B subunit	K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7]
D      Natgr_0219 glutamyl-tRNA(Gln) and/or aspartyl-tRNA(Asn) amidotransferase, C subunit	K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7]
D      Natgr_0739 glutamyl-tRNA(Gln) amidotransferase, subunit D	K09482 gatD; glutamyl-tRNA(Gln) amidotransferase subunit D [EC:6.3.5.7]
D      Natgr_3830 archaeal Glu-tRNAGln amidotransferase subunit E (contains GAD domain)	K03330 gatE; glutamyl-tRNA(Gln) amidotransferase subunit E [EC:6.3.5.7]
D      Natgr_2178 putative metal-dependent hydrolase related to alanyl-tRNA synthetase HxxxH domain protein	K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D      Natgr_1631 alanine--tRNA ligase/alanyl-tRNA synthetase	K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D      Natgr_2924 alanyl-tRNA synthetase	K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D      Natgr_2086 aspartyl-tRNA synthetase, archaeal type	K09759 aspC; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23]
D      Natgr_1431 glycyl-tRNA synthetase, dimeric type	K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D      Natgr_2477 threonyl-tRNA synthetase	K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D      Natgr_1213 seryl-tRNA synthetase	K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D      Natgr_3816 cysteinyl-tRNA synthetase	K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D      Natgr_0647 methionyl-tRNA synthetase	K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D      Natgr_2414 methionyl-tRNA formyltransferase	K00604 MTFMT; methionyl-tRNA formyltransferase [EC:2.1.2.9]
D      Natgr_0234 valyl-tRNA synthetase	K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D      Natgr_1393 leucyl-tRNA synthetase	K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D      Natgr_1682 isoleucyl-tRNA synthetase	K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D      Natgr_3390 lysyl-tRNA synthetase (class II)	K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D      Natgr_2416 lysyl-tRNA synthetase, archaeal and spirochete	K04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6]
D      Natgr_0694 arginyl-tRNA synthetase	K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D      Natgr_0967 prolyl-tRNA synthetase	K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D      Natgr_3663 prolyl-tRNA synthetase, family I	K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D      Natgr_2429 histidyl-tRNA synthetase	K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D      Natgr_1384 phenylalanyl-tRNA synthetase, alpha subunit	K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D      Natgr_1385 phenylalanyl-tRNA synthetase, beta subunit	K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D      Natgr_2215 tyrosyl-tRNA synthetase	K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D      Natgr_1376 tryptophanyl-tRNA synthetase	K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D      Natgr_1730 tryptophanyl-tRNA synthetase	K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
C    03013 Nucleocytoplasmic transport
C    03015 mRNA surveillance pathway
C    03008 Ribosome biogenesis in eukaryotes
B
B  09123 Folding, sorting and degradation
C    03060 Protein export [PATH:nge03060]
D      Natgr_0292 preprotein translocase, SecY subunit	K03076 secY; preprotein translocase subunit SecY
D      Natgr_1019 preprotein translocase subunit SecD	K03072 secD; preprotein translocase subunit SecD
D      Natgr_1018 preprotein translocase subunit SecF	K03074 secF; preprotein translocase subunit SecF
D      Natgr_1557 signal recognition particle GTPase	K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
D      Natgr_1543 signal recognition particle-docking protein FtsY	K03110 ftsY; fused signal recognition particle receptor
D      Natgr_2218 protein translocase SEC61 complex gamma subunit, archaeal and eukaryotic	K07342 SEC61G; protein transport protein SEC61 subunit gamma and related proteins
D      Natgr_3822 signal recognition particle 19 kDa protein	K03105 SRP19; signal recognition particle subunit SRP19
D      Natgr_2038 arsenite-activated ATPase ArsA	K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-]
D      Natgr_0819 arsenite-activated ATPase ArsA	K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-]
D      Natgr_1722 arsenite-activated ATPase ArsA	K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-]
D      Natgr_3580 arsenite-activated ATPase ArsA	K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-]
D      Natgr_0500 twin arginine-targeting protein translocase, TatA/E family	K03116 tatA; sec-independent protein translocase protein TatA
D      Natgr_1488 Sec-independent protein secretion pathway component TatC	K03118 tatC; sec-independent protein translocase protein TatC
D      Natgr_1489 Sec-independent protein secretion pathway component TatC	K03118 tatC; sec-independent protein translocase protein TatC
D      Natgr_1593 signal peptidase I	K13280 SEC11; signal peptidase I [EC:3.4.21.89]
D      Natgr_1574 signal peptidase I	K13280 SEC11; signal peptidase I [EC:3.4.21.89]
D      Natgr_1964 signal peptidase I	K13280 SEC11; signal peptidase I [EC:3.4.21.89]
D      Natgr_3395 signal peptidase I	K13280 SEC11; signal peptidase I [EC:3.4.21.89]
C    04141 Protein processing in endoplasmic reticulum
C    04130 SNARE interactions in vesicular transport
C    04120 Ubiquitin mediated proteolysis
C    04122 Sulfur relay system [PATH:nge04122]
D      Natgr_2191 rhodanese-related sulfurtransferase	K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]
D      Natgr_3159 rhodanese-related sulfurtransferase	K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]
D      Natgr_3655 rhodanese-related sulfurtransferase	K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]
D      Natgr_2859 putative redox protein, regulator of disulfide bond formation	K04085 tusA; tRNA 2-thiouridine synthesizing protein A [EC:2.8.1.-]
D      Natgr_0546 putative redox protein, regulator of disulfide bond formation	K04085 tusA; tRNA 2-thiouridine synthesizing protein A [EC:2.8.1.-]
D      Natgr_2420 molybdopterin converting factor, large subunit	K03635 MOCS2B; molybdopterin synthase catalytic subunit [EC:2.8.1.12]
D      Natgr_2706 putative molybdenum cofactor biosynthesis protein A, archaeal	K03639 moaA; GTP 3',8-cyclase [EC:4.1.99.22]
D      Natgr_1063 MoaD family protein	K03636 moaD; sulfur-carrier protein
D      Natgr_1128 MoaD family protein	K03636 moaD; sulfur-carrier protein
D      Natgr_3105 molybdopterin converting factor, small subunit	K03636 moaD; sulfur-carrier protein
D      Natgr_0373 molybdenum cofactor biosynthesis protein MoaC	K03637 moaC; cyclic pyranopterin monophosphate synthase [EC:4.6.1.17]
D      Natgr_1004 molybdopterin biosynthesis enzyme	K03638 moaB; molybdopterin adenylyltransferase [EC:2.7.7.75]
D      Natgr_1300 molybdenum cofactor synthesis domain protein	K03638 moaB; molybdopterin adenylyltransferase [EC:2.7.7.75]
D      Natgr_0131 thiamine biosynthesis ATP pyrophosphatase	K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]
D      Natgr_1638 sulfur transfer protein involved in thiamine biosynthesis	K03154 thiS; sulfur carrier protein
C    03050 Proteasome [PATH:nge03050]
D      Natgr_0854 26S proteasome subunit P45 family	K03420 psmR; proteasome regulatory subunit
D      Natgr_1970 26S proteasome subunit P45 family	K03420 psmR; proteasome regulatory subunit
D      Natgr_3644 proteasome endopeptidase complex, archaeal, alpha subunit	K03432 psmA; proteasome alpha subunit [EC:3.4.25.1]
D      Natgr_3623 proteasome endopeptidase complex, archaeal, beta subunit	K03433 psmB; proteasome beta subunit [EC:3.4.25.1]
C    03018 RNA degradation [PATH:nge03018]
D      Natgr_2561 phosphopyruvate hydratase	K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D      Natgr_2730 exoribonuclease R	K12573 rnr; ribonuclease R [EC:3.1.13.1]
D      Natgr_2569 putative hydrolase of the metallo-beta-lactamase superfamily	K12574 rnj; ribonuclease J [EC:3.1.-.-]
D      Natgr_3218 chaperone protein DnaK	K04043 dnaK; molecular chaperone DnaK
B
B  09124 Replication and repair
C    03030 DNA replication [PATH:nge03030]
D      Natgr_3187 DNA primase	K02316 dnaG; DNA primase [EC:2.7.7.101]
D      Natgr_1811 ribonuclease HI	K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D      Natgr_2543 ribonuclease HI	K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D      Natgr_1020 ribonuclease H, mammalian HI/archaeal HII subfamily	K03470 rnhB; ribonuclease HII [EC:3.1.26.4]
D      Natgr_1725 DNA ligase, NAD-dependent	K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D      Natgr_0568 DNA polymerase elongation subunit (family B)	K02319 pol; DNA polymerase, archaea type [EC:2.7.7.7]
D      Natgr_1592 archaeal DNA polymerase II, small subunit/DNA polymerase delta, subunit B	K02323 polB; DNA polymerase II small subunit [EC:2.7.7.7]
D      Natgr_1449 DNA polymerase type II, large subunit	K02322 polC; DNA polymerase II large subunit [EC:2.7.7.7]
D      Natgr_1738 putative ATPase involved in replication control, Cdc46/Mcm family	K10726 mcm; replicative DNA helicase Mcm [EC:5.6.2.3]
D      Natgr_3416 putative ATPase involved in replication control, Cdc46/Mcm family	K10726 mcm; replicative DNA helicase Mcm [EC:5.6.2.3]
D      Natgr_3532 putative ATPase involved in replication control, Cdc46/Mcm family	K10726 mcm; replicative DNA helicase Mcm [EC:5.6.2.3]
D      Natgr_3709 DNA primase, eukaryotic-type, small subunit, putative	K02683 priS; DNA primase small subunit [EC:2.7.7.102]
D      Natgr_1479 DNA primase, large subunit	K18882 priL; DNA primase large subunit
D      Natgr_1289 single-stranded DNA-binding protein	K07466 RFA1; replication factor A1
D      Natgr_1476 DNA polymerase sliding clamp subunit	K04802 PCNA; proliferating cell nuclear antigen
D      Natgr_2659 Proliferating cell nuclear antigen, N-terminal domain protein	K04802 PCNA; proliferating cell nuclear antigen
D      Natgr_1805 DNA polymerase III, gamma/tau subunit	K04801 rfcS; replication factor C small subunit
D      Natgr_1637 DNA polymerase III, gamma/tau subunit	K04801 rfcS; replication factor C small subunit
D      Natgr_3497 AAA ATPase	K04800 rfcL; replication factor C large subunit
D      Natgr_2069 DNA/RNA helicase, superfamily I	K10742 DNA2; DNA replication ATP-dependent helicase/nuclease Dna2 [EC:5.6.2.3 3.1.-.-]
D      Natgr_0722 flap structure-specific endonuclease	K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D      Natgr_0319 ATP-dependent DNA ligase I	K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
C    03410 Base excision repair [PATH:nge03410]
D      Natgr_0381 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase	K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18]
D      Natgr_0453 endonuclease III	K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D      Natgr_2535 putative endoIII-related endonuclease	K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D      Natgr_3781 A/G-specific DNA glycosylase	K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
D      Natgr_1476 DNA polymerase sliding clamp subunit	K04802 PCNA; proliferating cell nuclear antigen
D      Natgr_2659 Proliferating cell nuclear antigen, N-terminal domain protein	K04802 PCNA; proliferating cell nuclear antigen
D      Natgr_0722 flap structure-specific endonuclease	K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D      Natgr_0319 ATP-dependent DNA ligase I	K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
D      Natgr_0479 HhH-GPD superfamily base excision DNA repair protein	K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
D      Natgr_2015 uracil-DNA glycosylase, family 4	K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
D      Natgr_3379 uracil-DNA glycosylase	K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
D      Natgr_0395 uracil-DNA glycosylase	K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
D      Natgr_2497 apurinic endonuclease APN1	K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
D      Natgr_1455 single-stranded DNA-specific exonuclease	K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D      Natgr_1725 DNA ligase, NAD-dependent	K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
C    03420 Nucleotide excision repair [PATH:nge03420]
D      Natgr_2117 excinuclease ABC, A subunit	K03701 uvrA; excinuclease ABC subunit A
D      Natgr_1510 excinuclease ABC, B subunit	K03702 uvrB; excinuclease ABC subunit B
D      Natgr_1717 excinuclease ABC, C subunit	K03703 uvrC; excinuclease ABC subunit C
D      Natgr_1189 DNA/RNA helicase, superfamily I	K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D      Natgr_1725 DNA ligase, NAD-dependent	K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D      Natgr_3560 DNA/RNA helicase, superfamily II	K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
D      Natgr_1604 DNA helicase, Rad3	K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
D      Natgr_1641 DNA helicase, Rad3	K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
D      Natgr_1289 single-stranded DNA-binding protein	K07466 RFA1; replication factor A1
D      Natgr_1476 DNA polymerase sliding clamp subunit	K04802 PCNA; proliferating cell nuclear antigen
D      Natgr_2659 Proliferating cell nuclear antigen, N-terminal domain protein	K04802 PCNA; proliferating cell nuclear antigen
D      Natgr_0319 ATP-dependent DNA ligase I	K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
C    03430 Mismatch repair [PATH:nge03430]
D      Natgr_2401 DNA mismatch repair protein MutS	K03555 mutS; DNA mismatch repair protein MutS
D      Natgr_3084 DNA mismatch repair protein MutS	K03555 mutS; DNA mismatch repair protein MutS
D      Natgr_2102 MutS domain V	K07456 mutS2; DNA mismatch repair protein MutS2
D      Natgr_1505 mismatch repair ATPase (MutS family)	K07456 mutS2; DNA mismatch repair protein MutS2
D      Natgr_2724 DNA mismatch repair protein MutL	K03572 mutL; DNA mismatch repair protein MutL
D      Natgr_1189 DNA/RNA helicase, superfamily I	K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D      Natgr_1455 single-stranded DNA-specific exonuclease	K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D      Natgr_1725 DNA ligase, NAD-dependent	K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D      Natgr_0150 site-specific DNA methylase	K06223 dam; DNA adenine methylase [EC:2.1.1.72]
D      Natgr_1476 DNA polymerase sliding clamp subunit	K04802 PCNA; proliferating cell nuclear antigen
D      Natgr_2659 Proliferating cell nuclear antigen, N-terminal domain protein	K04802 PCNA; proliferating cell nuclear antigen
D      Natgr_1289 single-stranded DNA-binding protein	K07466 RFA1; replication factor A1
D      Natgr_0319 ATP-dependent DNA ligase I	K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
C    03440 Homologous recombination [PATH:nge03440]
D      Natgr_1455 single-stranded DNA-specific exonuclease	K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D      Natgr_1289 single-stranded DNA-binding protein	K07466 RFA1; replication factor A1
C    03450 Non-homologous end-joining
D      Natgr_0722 flap structure-specific endonuclease	K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
C    03460 Fanconi anemia pathway
B
B  09126 Chromosome
C    03082 ATP-dependent chromatin remodeling
C    03083 Polycomb repressive complex
B
B  09125 Information processing in viruses
C    03230 Viral genome structure
C    03240 Viral replication
C    03250 Viral life cycle - HIV-1 [PATH:nge03250]
D      Natgr_1173 peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	K03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8]
D      Natgr_1174 peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	K03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8]
D      Natgr_2316 DNA-directed RNA polymerase, subunit E''	K15171 SUPT4H1; transcription elongation factor SPT4
D      Natgr_2217 ribosomal protein L24p/L26e, archaeal	K15172 SUPT5H; transcription elongation factor SPT5
C    03260 Virion - Human immunodeficiency virus
C    03271 Virion - Rotavirus
C    03262 Virion - Coronavirus
C    03261 Virion - Influenza virus
C    03263 Virion - Enterovirus
C    03264 Virion - Flavivirus
C    03265 Virion - Ebolavirus and Lyssavirus
C    03266 Virion - Herpesvirus
C    03268 Virion - Orthopoxvirus
C    03267 Virion - Adenovirus
C    03259 Virion - Bacteriophages T4 and T7
C    03258 Virion - Bacteriophage lambda
#
A09130 Environmental Information Processing
B
B  09131 Membrane transport
C    02010 ABC transporters [PATH:nge02010]
D      Natgr_3201 ABC-type tungstate transport system, permease component	K05772 tupA; tungstate transport system substrate-binding protein
D      Natgr_3202 ABC-type tungstate transport system, periplasmic component	K05773 tupB; tungstate transport system permease protein
D      Natgr_3203 ABC-type polar amino acid transport system, ATPase component	K06857 tupC; tungstate transport system ATP-binding protein [EC:7.3.2.6]
D      Natgr_2390 ABC-type molybdate transport system, periplasmic component	K15495 wtpA; molybdate/tungstate transport system substrate-binding protein
D      Natgr_2389 NifC-like ABC-type porter	K15496 wtpB; molybdate/tungstate transport system permease protein
D      Natgr_2388 ABC-type spermidine/putrescine transport system, ATPase component	K15497 wtpC; molybdate/tungstate transport system ATP-binding protein [EC:7.3.2.5 7.3.2.6]
D      Natgr_1602 ABC-type Fe3+ transport system, periplasmic component	K02012 afuA; iron(III) transport system substrate-binding protein
D      Natgr_1601 ABC-type Fe3+ transport system, permease component	K02011 afuB; iron(III) transport system permease protein
D      Natgr_0730 ABC-type spermidine/putrescine transport system, ATPase component	K02010 afuC; iron(III) transport system ATP-binding protein [EC:7.2.2.7]
D      Natgr_1587 ABC transporter periplasmic binding protein, thiB subfamily	K02064 thiB; thiamine transport system substrate-binding protein
D      Natgr_2373 ABC transporter periplasmic binding protein, thiB subfamily	K02064 thiB; thiamine transport system substrate-binding protein
D      Natgr_2375 ABC-type Fe3+ transport system, permease component	K02063 thiP; thiamine transport system permease protein
D      Natgr_2376 ABC-type spermidine/putrescine transport system, ATPase component	K02062 thiQ; thiamine transport system ATP-binding protein [EC:7.6.2.15]
D      Natgr_2534 spermidine/putrescine-binding periplasmic protein	K11069 potD; spermidine/putrescine transport system substrate-binding protein
D      Natgr_2531 ABC-type spermidine/putrescine transport system, permease component II	K11070 potC; spermidine/putrescine transport system permease protein
D      Natgr_2532 ABC-type spermidine/putrescine transport system, permease component I	K11071 potB; spermidine/putrescine transport system permease protein
D      Natgr_2533 ABC-type spermidine/putrescine transport system, ATPase component	K11072 potA; spermidine/putrescine transport system ATP-binding protein [EC:7.6.2.11]
D      Natgr_1628 ATPase component of ABC-type sugar transporter	K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
D      Natgr_3625 ATPase component of ABC-type sugar transporter	K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
D      Natgr_3628 ABC-type sugar transport system, periplasmic component	K17315 gtsA; glucose/mannose transport system substrate-binding protein
D      Natgr_3627 permease component of ABC-type sugar transporter	K17316 gtsB; glucose/mannose transport system permease protein
D      Natgr_3626 ABC-type sugar transport system, permease component	K17317 gtsC; glucose/mannose transport system permease protein
D      Natgr_0756 ABC-type phosphate transport system, periplasmic component	K02040 pstS; phosphate transport system substrate-binding protein
D      Natgr_0352 ABC-type phosphate transport system, periplasmic component	K02040 pstS; phosphate transport system substrate-binding protein
D      Natgr_2800 ABC-type phosphate transport system, periplasmic component	K02040 pstS; phosphate transport system substrate-binding protein
D      Natgr_0755 phosphate ABC transporter, permease protein PstC	K02037 pstC; phosphate transport system permease protein
D      Natgr_0351 phosphate ABC transporter, permease protein PstC	K02037 pstC; phosphate transport system permease protein
D      Natgr_2799 phosphate ABC transporter, permease protein PstC	K02037 pstC; phosphate transport system permease protein
D      Natgr_0754 ABC-type phosphate transport system, permease component	K02038 pstA; phosphate transport system permease protein
D      Natgr_0350 phosphate ABC transporter, permease protein PstA	K02038 pstA; phosphate transport system permease protein
D      Natgr_2798 phosphate ABC transporter, permease protein PstA	K02038 pstA; phosphate transport system permease protein
D      Natgr_0349 phosphate ABC transporter, ATP-binding protein	K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]
D      Natgr_2797 phosphate ABC transporter, ATP-binding protein	K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]
D      Natgr_0753 ABC-type phosphate transport system, ATPase component	K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]
D      Natgr_1367 ABC-type phosphate/phosphonate transport system, periplasmic component	K02044 phnD; phosphonate transport system substrate-binding protein
D      Natgr_2792 phosphate/phosphite/phosphonate ABC transporters, periplasmic binding protein	K02044 phnD; phosphonate transport system substrate-binding protein
D      Natgr_1365 phosphonate ABC transporter, permease protein PhnE	K02042 phnE; phosphonate transport system permease protein
D      Natgr_2789 phosphonate ABC transporter, permease protein PhnE	K02042 phnE; phosphonate transport system permease protein
D      Natgr_2790 phosphonate ABC transporter, permease protein PhnE	K02042 phnE; phosphonate transport system permease protein
D      Natgr_1366 phosphonate ABC transporter, ATP-binding protein	K02041 phnC; phosphonate transport system ATP-binding protein [EC:7.3.2.2]
D      Natgr_2791 phosphonate ABC transporter, ATP-binding protein	K02041 phnC; phosphonate transport system ATP-binding protein [EC:7.3.2.2]
D      Natgr_1238 ABC-type branched-chain amino acid transport system, periplasmic component	K01999 livK; branched-chain amino acid transport system substrate-binding protein
D      Natgr_2125 ABC-type branched-chain amino acid transport system, periplasmic component	K01999 livK; branched-chain amino acid transport system substrate-binding protein
D      Natgr_1204 ABC-type branched-chain amino acid transport system, periplasmic component	K01999 livK; branched-chain amino acid transport system substrate-binding protein
D      Natgr_0884 ABC-type branched-chain amino acid transport system, periplasmic component	K01999 livK; branched-chain amino acid transport system substrate-binding protein
D      Natgr_1991 ABC-type branched-chain amino acid transport system, periplasmic component	K01999 livK; branched-chain amino acid transport system substrate-binding protein
D      Natgr_0880 branched-chain amino acid ABC-type transport system, permease component	K01997 livH; branched-chain amino acid transport system permease protein
D      Natgr_1239 branched-chain amino acid ABC-type transport system, permease component	K01997 livH; branched-chain amino acid transport system permease protein
D      Natgr_0881 ABC-type branched-chain amino acid transport system, permease component	K01998 livM; branched-chain amino acid transport system permease protein
D      Natgr_1240 ABC-type branched-chain amino acid transport systems, ATPase component	K01995 livG; branched-chain amino acid transport system ATP-binding protein
D      Natgr_0882 ABC-type branched-chain amino acid transport systems, ATPase component	K01995 livG; branched-chain amino acid transport system ATP-binding protein
D      Natgr_0883 ABC-type branched-chain amino acid transport systems, ATPase component	K01996 livF; branched-chain amino acid transport system ATP-binding protein
D      Natgr_1241 ABC-type branched-chain amino acid transport systems, ATPase component	K01996 livF; branched-chain amino acid transport system ATP-binding protein
D      Natgr_0092 ABC-type metal ion transport system, periplasmic component/surface adhesin	K09815 znuA; zinc transport system substrate-binding protein
D      Natgr_3227 ABC-type metal ion transport system, periplasmic component/surface adhesin	K09815 znuA; zinc transport system substrate-binding protein
D      Natgr_0094 ABC-type Mn2+/Zn2+ transport system, permease component	K09816 znuB; zinc transport system permease protein
D      Natgr_3229 ABC-type Mn2+/Zn2+ transport system, permease component	K09816 znuB; zinc transport system permease protein
D      Natgr_0093 ATPase component of Mn/Zn ABC-type transporter	K09817 znuC; zinc transport system ATP-binding protein [EC:7.2.2.20]
D      Natgr_3228 ATPase component of Mn/Zn ABC-type transporter	K09817 znuC; zinc transport system ATP-binding protein [EC:7.2.2.20]
D      Natgr_2772 hypothetical protein	K03523 bioY; biotin transport system substrate-specific component
D      Natgr_2770 ABC-type cobalt transport system, permease component CbiQ	K16783 bioN; biotin transport system permease protein
D      Natgr_2771 ABC-type cobalt transport system, ATPase component	K16784 bioM; biotin transport system ATP-binding protein [EC:7.6.2.-]
D      Natgr_3136 ABC-type transport system involved in cytochrome c biogenesis, permease component	K02195 ccmC; heme exporter protein C
D      Natgr_3129 ABC-type transport system involved in cytochrome c biogenesis, permease component	K02194 ccmB; heme exporter protein B
D      Natgr_3130 ABC-type multidrug transport system, ATPase component	K02193 ccmA; heme exporter protein A [EC:7.6.2.5]
D      Natgr_2391 hypothetical protein	K19341 nosY; Cu-processing system permease protein
D      Natgr_2392 ABC-type multidrug transport system, ATPase component	K19340 nosF; Cu-processing system ATP-binding protein
D      Natgr_2393 nitrous oxidase accessory protein	K07218 nosD; nitrous oxidase accessory protein
C    02060 Phosphotransferase system (PTS)
C    03070 Bacterial secretion system [PATH:nge03070]
D      Natgr_1019 preprotein translocase subunit SecD	K03072 secD; preprotein translocase subunit SecD
D      Natgr_1018 preprotein translocase subunit SecF	K03074 secF; preprotein translocase subunit SecF
D      Natgr_0292 preprotein translocase, SecY subunit	K03076 secY; preprotein translocase subunit SecY
D      Natgr_1543 signal recognition particle-docking protein FtsY	K03110 ftsY; fused signal recognition particle receptor
D      Natgr_1557 signal recognition particle GTPase	K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
D      Natgr_0500 twin arginine-targeting protein translocase, TatA/E family	K03116 tatA; sec-independent protein translocase protein TatA
D      Natgr_1488 Sec-independent protein secretion pathway component TatC	K03118 tatC; sec-independent protein translocase protein TatC
D      Natgr_1489 Sec-independent protein secretion pathway component TatC	K03118 tatC; sec-independent protein translocase protein TatC
B
B  09132 Signal transduction
C    02020 Two-component system [PATH:nge02020]
D      Natgr_0756 ABC-type phosphate transport system, periplasmic component	K02040 pstS; phosphate transport system substrate-binding protein
D      Natgr_0352 ABC-type phosphate transport system, periplasmic component	K02040 pstS; phosphate transport system substrate-binding protein
D      Natgr_2800 ABC-type phosphate transport system, periplasmic component	K02040 pstS; phosphate transport system substrate-binding protein
D      Natgr_1023 trypsin-like serine protease with C-terminal PDZ domain	K04771 degP; serine protease Do [EC:3.4.21.107]
D      Natgr_2220 trypsin-like serine protease with C-terminal PDZ domain	K04771 degP; serine protease Do [EC:3.4.21.107]
D      Natgr_0392 uncharacterized protein required for cytochrome oxidase assembly	K02259 COX15; heme a synthase [EC:1.17.99.9]
D      Natgr_0576 citrate lyase beta subunit	K01644 citE; citrate lyase subunit beta / citryl-CoA lyase [EC:4.1.3.34]
D      Natgr_3782 Triphosphoribosyl-dephospho-CoA synthetase	K05966 citG; triphosphoribosyl-dephospho-CoA synthase [EC:2.4.2.52]
D      Natgr_2338 glutamine synthetase	K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D      Natgr_3111 glutamine synthetase, type I	K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D      Natgr_1318 short chain fatty acids transporter	K02106 atoE; short-chain fatty acids transporter
D      Natgr_0823 acetyl-CoA acetyltransferase	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      Natgr_0426 acetyl-CoA acetyltransferase	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      Natgr_1255 acetyl-CoA acetyltransferase	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      Natgr_3067 acetyl-CoA acetyltransferase	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      Natgr_3496 acetyl-CoA acetyltransferase	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      Natgr_2159 Ni,Fe-hydrogenase I large subunit	K23549 hupV; uptake hydrogenase large subunit [EC:1.12.99.6]
D      Natgr_2158 Ni,Fe-hydrogenase I small subunit	K06282 hyaA; hydrogenase small subunit [EC:1.12.99.6]
D      Natgr_2160 Prokaryotic cytochrome b561	K03620 hyaC; Ni/Fe-hydrogenase 1 B-type cytochrome subunit
D      Natgr_0511 methylase of chemotaxis methyl-accepting protein	K00575 cheR; chemotaxis protein methyltransferase CheR [EC:2.1.1.80]
D      Natgr_0256 PAS domain S-box	K03406 mcp; methyl-accepting chemotaxis protein
D      Natgr_0873 methyl-accepting chemotaxis protein	K03406 mcp; methyl-accepting chemotaxis protein
D      Natgr_1099 methyl-accepting chemotaxis protein	K03406 mcp; methyl-accepting chemotaxis protein
D      Natgr_0338 methyl-accepting chemotaxis protein	K03406 mcp; methyl-accepting chemotaxis protein
D      Natgr_1205 methyl-accepting chemotaxis protein	K03406 mcp; methyl-accepting chemotaxis protein
D      Natgr_1208 methyl-accepting chemotaxis protein	K03406 mcp; methyl-accepting chemotaxis protein
D      Natgr_2126 methyl-accepting chemotaxis protein	K03406 mcp; methyl-accepting chemotaxis protein
D      Natgr_1990 methyl-accepting chemotaxis protein	K03406 mcp; methyl-accepting chemotaxis protein
D      Natgr_1906 methyl-accepting chemotaxis protein	K03406 mcp; methyl-accepting chemotaxis protein
D      Natgr_1801 methyl-accepting chemotaxis protein	K03406 mcp; methyl-accepting chemotaxis protein
D      Natgr_1804 methyl-accepting chemotaxis protein	K03406 mcp; methyl-accepting chemotaxis protein
D      Natgr_1654 methyl-accepting chemotaxis protein	K03406 mcp; methyl-accepting chemotaxis protein
D      Natgr_2826 methyl-accepting chemotaxis protein	K03406 mcp; methyl-accepting chemotaxis protein
D      Natgr_3116 methyl-accepting chemotaxis protein	K03406 mcp; methyl-accepting chemotaxis protein
D      Natgr_3162 methyl-accepting chemotaxis protein	K03406 mcp; methyl-accepting chemotaxis protein
D      Natgr_3559 methyl-accepting chemotaxis protein	K03406 mcp; methyl-accepting chemotaxis protein
D      Natgr_3799 PAS domain S-box	K03406 mcp; methyl-accepting chemotaxis protein
D      Natgr_0518 chemotaxis signal transduction protein	K03408 cheW; purine-binding chemotaxis protein CheW
D      Natgr_1959 chemotaxis signal transduction protein	K03408 cheW; purine-binding chemotaxis protein CheW
D      Natgr_0515 chemotaxis protein histidine kinase-like protein	K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
D      Natgr_1954 chemotaxis protein histidine kinase-like protein	K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
D      Natgr_0517 response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain	K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
D      Natgr_1953 response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
D      Natgr_0516 chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain	K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
D      Natgr_1955 chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain	K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
D      Natgr_0317 cytochrome bd-type quinol oxidase, subunit 1	K00425 cydA; cytochrome bd ubiquinol oxidase subunit I [EC:7.1.1.7]
D      Natgr_3146 cytochrome bd-type quinol oxidase, subunit 1	K00425 cydA; cytochrome bd ubiquinol oxidase subunit I [EC:7.1.1.7]
D      Natgr_0318 cytochrome bd-type quinol oxidase, subunit 2	K00426 cydB; cytochrome bd ubiquinol oxidase subunit II [EC:7.1.1.7]
D      Natgr_3145 cytochrome d oxidase cyd, subunit II	K00426 cydB; cytochrome bd ubiquinol oxidase subunit II [EC:7.1.1.7]
D      Natgr_2974 nucleotide sugar dehydrogenase	K02472 wecC; UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase [EC:1.1.1.336]
C    04010 MAPK signaling pathway
C    04013 MAPK signaling pathway - fly
C    04016 MAPK signaling pathway - plant
C    04011 MAPK signaling pathway - yeast
C    04012 ErbB signaling pathway
C    04014 Ras signaling pathway
C    04015 Rap1 signaling pathway
C    04310 Wnt signaling pathway
C    04330 Notch signaling pathway
C    04340 Hedgehog signaling pathway
C    04341 Hedgehog signaling pathway - fly
C    04350 TGF-beta signaling pathway
C    04390 Hippo signaling pathway
C    04391 Hippo signaling pathway - fly
C    04392 Hippo signaling pathway - multiple species
C    04370 VEGF signaling pathway
C    04371 Apelin signaling pathway
C    04630 JAK-STAT signaling pathway
C    04064 NF-kappa B signaling pathway
C    04668 TNF signaling pathway
C    04066 HIF-1 signaling pathway
C    04068 FoxO signaling pathway
C    04020 Calcium signaling pathway
C    04070 Phosphatidylinositol signaling system
C    04072 Phospholipase D signaling pathway
C    04071 Sphingolipid signaling pathway
C    04024 cAMP signaling pathway
C    04022 cGMP-PKG signaling pathway
C    04151 PI3K-Akt signaling pathway
C    04152 AMPK signaling pathway
C    04150 mTOR signaling pathway
C    04075 Plant hormone signal transduction
B
B  09133 Signaling molecules and interaction
C    04080 Neuroactive ligand-receptor interaction
C    04060 Cytokine-cytokine receptor interaction
C    04061 Viral protein interaction with cytokine and cytokine receptor
C    04512 ECM-receptor interaction
C    04514 Cell adhesion molecules
#
A09140 Cellular Processes
B
B  09141 Transport and catabolism
C    04144 Endocytosis
C    04145 Phagosome
C    04142 Lysosome
C    04146 Peroxisome
C    04140 Autophagy - animal
C    04138 Autophagy - yeast
C    04136 Autophagy - other
C    04137 Mitophagy - animal
C    04139 Mitophagy - yeast
C    04148 Efferocytosis
B
B  09143 Cell growth and death
C    04110 Cell cycle
C    04111 Cell cycle - yeast
C    04112 Cell cycle - Caulobacter
C    04113 Meiosis - yeast
C    04114 Oocyte meiosis
C    04210 Apoptosis
C    04214 Apoptosis - fly
C    04215 Apoptosis - multiple species
C    04216 Ferroptosis
C    04217 Necroptosis
C    04115 p53 signaling pathway
C    04218 Cellular senescence
B
B  09144 Cellular community - eukaryotes
C    04510 Focal adhesion
C    04520 Adherens junction
C    04530 Tight junction
C    04540 Gap junction
C    04550 Signaling pathways regulating pluripotency of stem cells
B
B  09145 Cellular community - prokaryotes
C    02024 Quorum sensing [PATH:nge02024]
D      Natgr_0946 aminodeoxychorismate synthase, component I, clade 2	K01657 trpE; anthranilate synthase component I [EC:4.1.3.27]
D      Natgr_3762 anthranilate synthase component I, archaeal clade	K01657 trpE; anthranilate synthase component I [EC:4.1.3.27]
D      Natgr_0945 glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase	K01658 trpG; anthranilate synthase component II [EC:4.1.3.27]
D      Natgr_3763 glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase	K01658 trpG; anthranilate synthase component II [EC:4.1.3.27]
D      Natgr_1238 ABC-type branched-chain amino acid transport system, periplasmic component	K01999 livK; branched-chain amino acid transport system substrate-binding protein
D      Natgr_2125 ABC-type branched-chain amino acid transport system, periplasmic component	K01999 livK; branched-chain amino acid transport system substrate-binding protein
D      Natgr_1204 ABC-type branched-chain amino acid transport system, periplasmic component	K01999 livK; branched-chain amino acid transport system substrate-binding protein
D      Natgr_0884 ABC-type branched-chain amino acid transport system, periplasmic component	K01999 livK; branched-chain amino acid transport system substrate-binding protein
D      Natgr_1991 ABC-type branched-chain amino acid transport system, periplasmic component	K01999 livK; branched-chain amino acid transport system substrate-binding protein
D      Natgr_0880 branched-chain amino acid ABC-type transport system, permease component	K01997 livH; branched-chain amino acid transport system permease protein
D      Natgr_1239 branched-chain amino acid ABC-type transport system, permease component	K01997 livH; branched-chain amino acid transport system permease protein
D      Natgr_0881 ABC-type branched-chain amino acid transport system, permease component	K01998 livM; branched-chain amino acid transport system permease protein
D      Natgr_1240 ABC-type branched-chain amino acid transport systems, ATPase component	K01995 livG; branched-chain amino acid transport system ATP-binding protein
D      Natgr_0882 ABC-type branched-chain amino acid transport systems, ATPase component	K01995 livG; branched-chain amino acid transport system ATP-binding protein
D      Natgr_0883 ABC-type branched-chain amino acid transport systems, ATPase component	K01996 livF; branched-chain amino acid transport system ATP-binding protein
D      Natgr_1241 ABC-type branched-chain amino acid transport systems, ATPase component	K01996 livF; branched-chain amino acid transport system ATP-binding protein
D      Natgr_1231 Zn-dependent hydrolase, glyoxylase	K13075 ahlD; N-acyl homoserine lactone hydrolase [EC:3.1.1.81]
D      Natgr_1229 AMP-forming long-chain acyl-CoA synthetase	K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D      Natgr_1230 AMP-forming long-chain acyl-CoA synthetase	K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D      Natgr_0618 extracellular solute-binding protein, family 5	K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D      Natgr_0620 extracellular solute-binding protein, family 5	K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D      Natgr_1149 extracellular solute-binding protein, family 5	K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D      Natgr_1440 ABC-type dipeptide transport system, periplasmic component	K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D      Natgr_1700 ABC-type dipeptide transport system, periplasmic component	K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D      Natgr_3314 ABC-type dipeptide transport system, periplasmic component	K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D      Natgr_3734 ABC-type dipeptide transport system, periplasmic component	K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D      Natgr_3739 ABC-type dipeptide transport system, periplasmic component	K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D      Natgr_0009 extracellular solute-binding protein, family 5	K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D      Natgr_1447 ABC-type dipeptide transport system, periplasmic component	K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D      Natgr_0807 ABC-type dipeptide/oligopeptide/nickel transport system, permease component	K02033 ABC.PE.P; peptide/nickel transport system permease protein
D      Natgr_0798 ABC-type dipeptide/oligopeptide/nickel transport system, permease component	K02033 ABC.PE.P; peptide/nickel transport system permease protein
D      Natgr_1150 ABC-type dipeptide/oligopeptide/nickel transport system, permease component	K02033 ABC.PE.P; peptide/nickel transport system permease protein
D      Natgr_1439 ABC-type dipeptide/oligopeptide/nickel transport system, permease component	K02033 ABC.PE.P; peptide/nickel transport system permease protein
D      Natgr_1446 ABC-type dipeptide/oligopeptide/nickel transport system, permease component	K02033 ABC.PE.P; peptide/nickel transport system permease protein
D      Natgr_1699 ABC-type dipeptide/oligopeptide/nickel transport system, permease component	K02033 ABC.PE.P; peptide/nickel transport system permease protein
D      Natgr_3311 ABC-type dipeptide/oligopeptide/nickel transport system, permease component	K02033 ABC.PE.P; peptide/nickel transport system permease protein
D      Natgr_3735 ABC-type dipeptide/oligopeptide/nickel transport system, permease component	K02033 ABC.PE.P; peptide/nickel transport system permease protein
D      Natgr_3740 ABC-type dipeptide/oligopeptide/nickel transport system, permease component	K02033 ABC.PE.P; peptide/nickel transport system permease protein
D      Natgr_0808 ABC-type dipeptide/oligopeptide/nickel transport system, permease component	K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D      Natgr_0799 ABC-type dipeptide/oligopeptide/nickel transport system, permease component	K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D      Natgr_1151 ABC-type dipeptide/oligopeptide/nickel transport system, permease component	K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D      Natgr_1438 ABC-type dipeptide/oligopeptide/nickel transport system, permease component	K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D      Natgr_1445 ABC-type dipeptide/oligopeptide/nickel transport system, permease component	K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D      Natgr_1698 ABC-type dipeptide/oligopeptide/nickel transport system, permease component	K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D      Natgr_3312 ABC-type dipeptide/oligopeptide/nickel transport system, permease component	K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D      Natgr_3741 ABC-type dipeptide/oligopeptide/nickel transport system, permease component	K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D      Natgr_3736 ABC-type dipeptide/oligopeptide/nickel transport system, permease component	K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D      Natgr_3737 oligopeptide/dipeptide ABC transporter, ATP-binding protein	K02031 ddpD; peptide/nickel transport system ATP-binding protein
D      Natgr_3313 oligopeptide/dipeptide ABC transporter, ATP-binding protein	K02031 ddpD; peptide/nickel transport system ATP-binding protein
D      Natgr_3742 oligopeptide/dipeptide ABC transporter, ATP-binding protein	K02031 ddpD; peptide/nickel transport system ATP-binding protein
D      Natgr_1444 oligopeptide/dipeptide ABC transporter, ATP-binding protein	K02031 ddpD; peptide/nickel transport system ATP-binding protein
D      Natgr_1697 oligopeptide/dipeptide ABC transporter, ATP-binding protein	K02031 ddpD; peptide/nickel transport system ATP-binding protein
D      Natgr_1152 oligopeptide/dipeptide ABC transporter, ATP-binding protein	K02031 ddpD; peptide/nickel transport system ATP-binding protein
D      Natgr_1437 oligopeptide/dipeptide ABC transporter, ATP-binding protein	K02031 ddpD; peptide/nickel transport system ATP-binding protein
D      Natgr_0800 oligopeptide/dipeptide ABC transporter, ATP-binding protein	K02031 ddpD; peptide/nickel transport system ATP-binding protein
D      Natgr_0809 oligopeptide/dipeptide ABC transporter, ATP-binding protein	K02031 ddpD; peptide/nickel transport system ATP-binding protein
D      Natgr_1443 oligopeptide/dipeptide ABC transporter, ATP-binding protein	K02032 ddpF; peptide/nickel transport system ATP-binding protein
D      Natgr_1153 oligopeptide/dipeptide ABC transporter, ATP-binding protein	K02032 ddpF; peptide/nickel transport system ATP-binding protein
D      Natgr_3738 oligopeptide/dipeptide ABC transporter, ATP-binding protein	K02032 ddpF; peptide/nickel transport system ATP-binding protein
D      Natgr_3743 oligopeptide/dipeptide ABC transporter, ATP-binding protein	K02032 ddpF; peptide/nickel transport system ATP-binding protein
D      Natgr_0810 oligopeptide/dipeptide ABC transporter, ATP-binding protein	K02032 ddpF; peptide/nickel transport system ATP-binding protein
D      Natgr_0801 oligopeptide/dipeptide ABC transporter, ATP-binding protein	K02032 ddpF; peptide/nickel transport system ATP-binding protein
D      Natgr_3024 subtilisin-like serine protease	K14645 K14645; serine protease [EC:3.4.21.-]
D      Natgr_0292 preprotein translocase, SecY subunit	K03076 secY; preprotein translocase subunit SecY
D      Natgr_1543 signal recognition particle-docking protein FtsY	K03110 ftsY; fused signal recognition particle receptor
D      Natgr_1557 signal recognition particle GTPase	K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
C    05111 Biofilm formation - Vibrio cholerae
C    02025 Biofilm formation - Pseudomonas aeruginosa
C    02026 Biofilm formation - Escherichia coli
B
B  09142 Cell motility
C    02030 Bacterial chemotaxis [PATH:nge02030]
D      Natgr_0256 PAS domain S-box	K03406 mcp; methyl-accepting chemotaxis protein
D      Natgr_0873 methyl-accepting chemotaxis protein	K03406 mcp; methyl-accepting chemotaxis protein
D      Natgr_1099 methyl-accepting chemotaxis protein	K03406 mcp; methyl-accepting chemotaxis protein
D      Natgr_0338 methyl-accepting chemotaxis protein	K03406 mcp; methyl-accepting chemotaxis protein
D      Natgr_1205 methyl-accepting chemotaxis protein	K03406 mcp; methyl-accepting chemotaxis protein
D      Natgr_1208 methyl-accepting chemotaxis protein	K03406 mcp; methyl-accepting chemotaxis protein
D      Natgr_2126 methyl-accepting chemotaxis protein	K03406 mcp; methyl-accepting chemotaxis protein
D      Natgr_1990 methyl-accepting chemotaxis protein	K03406 mcp; methyl-accepting chemotaxis protein
D      Natgr_1906 methyl-accepting chemotaxis protein	K03406 mcp; methyl-accepting chemotaxis protein
D      Natgr_1801 methyl-accepting chemotaxis protein	K03406 mcp; methyl-accepting chemotaxis protein
D      Natgr_1804 methyl-accepting chemotaxis protein	K03406 mcp; methyl-accepting chemotaxis protein
D      Natgr_1654 methyl-accepting chemotaxis protein	K03406 mcp; methyl-accepting chemotaxis protein
D      Natgr_2826 methyl-accepting chemotaxis protein	K03406 mcp; methyl-accepting chemotaxis protein
D      Natgr_3116 methyl-accepting chemotaxis protein	K03406 mcp; methyl-accepting chemotaxis protein
D      Natgr_3162 methyl-accepting chemotaxis protein	K03406 mcp; methyl-accepting chemotaxis protein
D      Natgr_3559 methyl-accepting chemotaxis protein	K03406 mcp; methyl-accepting chemotaxis protein
D      Natgr_3799 PAS domain S-box	K03406 mcp; methyl-accepting chemotaxis protein
D      Natgr_0515 chemotaxis protein histidine kinase-like protein	K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
D      Natgr_1954 chemotaxis protein histidine kinase-like protein	K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
D      Natgr_0518 chemotaxis signal transduction protein	K03408 cheW; purine-binding chemotaxis protein CheW
D      Natgr_1959 chemotaxis signal transduction protein	K03408 cheW; purine-binding chemotaxis protein CheW
D      Natgr_0517 response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain	K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
D      Natgr_1953 response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
D      Natgr_0513 chemotaxis protein CheC, inhibitor of MCP methylation	K03410 cheC; chemotaxis protein CheC
D      Natgr_0514 chemotaxis protein CheC, inhibitor of MCP methylation	K03410 cheC; chemotaxis protein CheC
D      Natgr_1473 chemotaxis protein CheC, inhibitor of MCP methylation	K03410 cheC; chemotaxis protein CheC
D      Natgr_1952 chemotaxis protein CheC, inhibitor of MCP methylation	K03410 cheC; chemotaxis protein CheC
D      Natgr_0516 chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain	K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
D      Natgr_1955 chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain	K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
D      Natgr_0512 chemotaxis protein	K03411 cheD; chemotaxis protein CheD [EC:3.5.1.44]
D      Natgr_1472 chemotaxis protein	K03411 cheD; chemotaxis protein CheD [EC:3.5.1.44]
D      Natgr_0511 methylase of chemotaxis methyl-accepting protein	K00575 cheR; chemotaxis protein methyltransferase CheR [EC:2.1.1.80]
C    02040 Flagellar assembly
C    04814 Motor proteins
C    04820 Cytoskeleton in muscle cells
D      Natgr_2561 phosphopyruvate hydratase	K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
C    04810 Regulation of actin cytoskeleton
#
A09150 Organismal Systems
B
B  09151 Immune system
C    04640 Hematopoietic cell lineage
C    04610 Complement and coagulation cascades
C    04611 Platelet activation
C    04613 Neutrophil extracellular trap formation
C    04620 Toll-like receptor signaling pathway
C    04624 Toll and Imd signaling pathway
C    04621 NOD-like receptor signaling pathway
C    04622 RIG-I-like receptor signaling pathway
C    04623 Cytosolic DNA-sensing pathway
C    04625 C-type lectin receptor signaling pathway
C    04650 Natural killer cell mediated cytotoxicity
C    04612 Antigen processing and presentation
C    04660 T cell receptor signaling pathway
C    04658 Th1 and Th2 cell differentiation
C    04659 Th17 cell differentiation
C    04657 IL-17 signaling pathway
C    04662 B cell receptor signaling pathway
C    04664 Fc epsilon RI signaling pathway
C    04666 Fc gamma R-mediated phagocytosis
C    04670 Leukocyte transendothelial migration
C    04672 Intestinal immune network for IgA production
C    04062 Chemokine signaling pathway
B
B  09152 Endocrine system
C    04911 Insulin secretion
C    04910 Insulin signaling pathway
C    04922 Glucagon signaling pathway
C    04923 Regulation of lipolysis in adipocytes
C    04920 Adipocytokine signaling pathway
C    03320 PPAR signaling pathway
C    04929 GnRH secretion
C    04912 GnRH signaling pathway
C    04913 Ovarian steroidogenesis
C    04915 Estrogen signaling pathway
C    04914 Progesterone-mediated oocyte maturation
C    04917 Prolactin signaling pathway
C    04921 Oxytocin signaling pathway
C    04926 Relaxin signaling pathway
C    04935 Growth hormone synthesis, secretion and action
C    04918 Thyroid hormone synthesis
C    04919 Thyroid hormone signaling pathway
C    04928 Parathyroid hormone synthesis, secretion and action
C    04916 Melanogenesis
C    04924 Renin secretion
C    04614 Renin-angiotensin system
C    04925 Aldosterone synthesis and secretion
C    04927 Cortisol synthesis and secretion
B
B  09153 Circulatory system
C    04260 Cardiac muscle contraction
C    04261 Adrenergic signaling in cardiomyocytes
C    04270 Vascular smooth muscle contraction
B
B  09154 Digestive system
C    04970 Salivary secretion
C    04971 Gastric acid secretion
C    04972 Pancreatic secretion
C    04976 Bile secretion
C    04973 Carbohydrate digestion and absorption
C    04974 Protein digestion and absorption
C    04975 Fat digestion and absorption
C    04979 Cholesterol metabolism
C    04977 Vitamin digestion and absorption
C    04980 Cobalamin transport and metabolism [PATH:nge04980]
D      Natgr_2873 ATP:cob(I)alamin adenosyltransferase	K00798 MMAB; cob(I)alamin adenosyltransferase [EC:2.5.1.17]
D      Natgr_0826 LAO/AO transport system ATPase	K07588 MMAA; GTPase [EC:3.6.5.-]
C    04978 Mineral absorption
B
B  09155 Excretory system
C    04962 Vasopressin-regulated water reabsorption
C    04960 Aldosterone-regulated sodium reabsorption
C    04961 Endocrine and other factor-regulated calcium reabsorption
C    04964 Proximal tubule bicarbonate reclamation
C    04966 Collecting duct acid secretion
B
B  09156 Nervous system
C    04724 Glutamatergic synapse
C    04727 GABAergic synapse
C    04725 Cholinergic synapse
C    04728 Dopaminergic synapse
C    04726 Serotonergic synapse
C    04720 Long-term potentiation
C    04730 Long-term depression
C    04723 Retrograde endocannabinoid signaling
C    04721 Synaptic vesicle cycle
C    04722 Neurotrophin signaling pathway
B
B  09157 Sensory system
C    04744 Phototransduction
C    04745 Phototransduction - fly
C    04740 Olfactory transduction
C    04742 Taste transduction
C    04750 Inflammatory mediator regulation of TRP channels
B
B  09158 Development and regeneration
C    04320 Dorso-ventral axis formation
C    04360 Axon guidance
C    04361 Axon regeneration
C    04380 Osteoclast differentiation
B
B  09149 Aging
C    04211 Longevity regulating pathway
C    04212 Longevity regulating pathway - worm
C    04213 Longevity regulating pathway - multiple species
B
B  09159 Environmental adaptation
C    04710 Circadian rhythm
C    04713 Circadian entrainment
C    04711 Circadian rhythm - fly
C    04712 Circadian rhythm - plant
C    04714 Thermogenesis
C    04626 Plant-pathogen interaction
#
A09160 Human Diseases
B
B  09161 Cancer: overview
C    05200 Pathways in cancer
C    05202 Transcriptional misregulation in cancer
C    05206 MicroRNAs in cancer
C    05205 Proteoglycans in cancer
C    05204 Chemical carcinogenesis - DNA adducts
C    05207 Chemical carcinogenesis - receptor activation
C    05208 Chemical carcinogenesis - reactive oxygen species
C    05203 Viral carcinogenesis
C    05230 Central carbon metabolism in cancer
C    05231 Choline metabolism in cancer
C    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
B
B  09162 Cancer: specific types
C    05210 Colorectal cancer
C    05212 Pancreatic cancer
C    05225 Hepatocellular carcinoma
C    05226 Gastric cancer
C    05214 Glioma
C    05216 Thyroid cancer
C    05221 Acute myeloid leukemia
C    05220 Chronic myeloid leukemia
C    05217 Basal cell carcinoma
C    05218 Melanoma
C    05211 Renal cell carcinoma
C    05219 Bladder cancer
C    05215 Prostate cancer
C    05213 Endometrial cancer
C    05224 Breast cancer
C    05222 Small cell lung cancer
C    05223 Non-small cell lung cancer
B
B  09172 Infectious disease: viral
C    05166 Human T-cell leukemia virus 1 infection
C    05170 Human immunodeficiency virus 1 infection
C    05161 Hepatitis B
C    05160 Hepatitis C
C    05171 Coronavirus disease - COVID-19
C    05164 Influenza A
C    05162 Measles
C    05168 Herpes simplex virus 1 infection
C    05163 Human cytomegalovirus infection
C    05167 Kaposi sarcoma-associated herpesvirus infection
C    05169 Epstein-Barr virus infection
C    05165 Human papillomavirus infection
B
B  09171 Infectious disease: bacterial
C    05110 Vibrio cholerae infection
C    05120 Epithelial cell signaling in Helicobacter pylori infection
C    05130 Pathogenic Escherichia coli infection
C    05132 Salmonella infection
C    05131 Shigellosis
C    05135 Yersinia infection
C    05133 Pertussis
C    05134 Legionellosis
C    05150 Staphylococcus aureus infection
C    05152 Tuberculosis
C    05100 Bacterial invasion of epithelial cells
B
B  09174 Infectious disease: parasitic
C    05146 Amoebiasis
C    05144 Malaria
C    05145 Toxoplasmosis
C    05140 Leishmaniasis
C    05142 Chagas disease
C    05143 African trypanosomiasis
B
B  09163 Immune disease
C    05310 Asthma
C    05322 Systemic lupus erythematosus
C    05323 Rheumatoid arthritis
C    05320 Autoimmune thyroid disease
C    05321 Inflammatory bowel disease
C    05330 Allograft rejection
C    05332 Graft-versus-host disease
C    05340 Primary immunodeficiency
B
B  09164 Neurodegenerative disease
C    05010 Alzheimer disease
C    05012 Parkinson disease
C    05014 Amyotrophic lateral sclerosis
C    05016 Huntington disease
C    05017 Spinocerebellar ataxia
C    05020 Prion disease
C    05022 Pathways of neurodegeneration - multiple diseases
B
B  09165 Substance dependence
C    05030 Cocaine addiction
C    05031 Amphetamine addiction
C    05032 Morphine addiction
C    05033 Nicotine addiction
C    05034 Alcoholism
B
B  09166 Cardiovascular disease
C    05417 Lipid and atherosclerosis
C    05418 Fluid shear stress and atherosclerosis
C    05410 Hypertrophic cardiomyopathy
C    05412 Arrhythmogenic right ventricular cardiomyopathy
C    05414 Dilated cardiomyopathy
C    05415 Diabetic cardiomyopathy
C    05416 Viral myocarditis
B
B  09167 Endocrine and metabolic disease
C    04930 Type II diabetes mellitus
C    04940 Type I diabetes mellitus
C    04950 Maturity onset diabetes of the young
C    04936 Alcoholic liver disease
C    04932 Non-alcoholic fatty liver disease
C    04931 Insulin resistance
C    04933 AGE-RAGE signaling pathway in diabetic complications
C    04934 Cushing syndrome
B
B  09175 Drug resistance: antimicrobial
C    01501 beta-Lactam resistance
C    01502 Vancomycin resistance
C    01503 Cationic antimicrobial peptide (CAMP) resistance [PATH:nge01503]
D      Natgr_1023 trypsin-like serine protease with C-terminal PDZ domain	K04771 degP; serine protease Do [EC:3.4.21.107]
D      Natgr_2220 trypsin-like serine protease with C-terminal PDZ domain	K04771 degP; serine protease Do [EC:3.4.21.107]
D      Natgr_1173 peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	K03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8]
D      Natgr_1174 peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	K03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8]
B
B  09176 Drug resistance: antineoplastic
C    01521 EGFR tyrosine kinase inhibitor resistance
C    01524 Platinum drug resistance
C    01523 Antifolate resistance
C    01522 Endocrine resistance
#
A09180 Brite Hierarchies
B
B  09181 Protein families: metabolism
C    01000 Enzymes [BR:nge01000]
C    01001 Protein kinases [BR:nge01001]
D      Natgr_2108 metallohydrolase, glycoprotease/Kae1 family	K15904 kae1-bud32; bifunctional N6-L-threonylcarbamoyladenine synthase / protein kinase Bud32 [EC:2.3.1.234 2.7.11.1]
D      Natgr_1728 serine/threonine protein kinase involved in cell cycle control	K07178 RIOK1; RIO kinase 1 [EC:2.7.11.1]
D      Natgr_2483 RIO-like serine/threonine protein kinase fused to N-terminal HTH domain protein	K07179 RIOK2; RIO kinase 2 [EC:2.7.11.1]
D      Natgr_3725 PGF-CTERM archaeal protein-sorting signal	K12132 prkC; eukaryotic-like serine/threonine-protein kinase [EC:2.7.11.1]
D      Natgr_2094 protein kinase domain with FHA domain	K12132 prkC; eukaryotic-like serine/threonine-protein kinase [EC:2.7.11.1]
D      Natgr_0515 chemotaxis protein histidine kinase-like protein	K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
D      Natgr_1954 chemotaxis protein histidine kinase-like protein	K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
C    01009 Protein phosphatases and associated proteins [BR:nge01009]
D      Natgr_2755 translation initiation factor 2, beta subunit (eIF-2beta)/eIF-5 N-terminal domain protein	K03238 EIF2S2; translation initiation factor 2 subunit 2
D      Natgr_1780 adenosylhomocysteinase	K01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1]
D      Natgr_2095 serine/threonine protein phosphatase	K20074 prpC; PPM family protein phosphatase [EC:3.1.3.16]
D      Natgr_1427 phosphoserine phosphatase SerB	K01079 serB; phosphoserine phosphatase [EC:3.1.3.3]
C    01002 Peptidases and inhibitors [BR:nge01002]
D      Natgr_1743 leader peptidase family protein	K07991 flaK; archaeal preflagellin peptidase FlaK [EC:3.4.23.52]
D      Natgr_2161 hydrogenase maturation protease	K03605 hyaD; hydrogenase maturation protease [EC:3.4.23.-]
D      Natgr_2864 Ni,Fe-hydrogenase maturation factor	K03605 hyaD; hydrogenase maturation protease [EC:3.4.23.-]
D      Natgr_2107 pyroglutamyl peptidase I	K01304 pcp; pyroglutamyl-peptidase [EC:3.4.19.3]
D      Natgr_0737 GMP synthase, glutamine-hydrolyzing, N-terminal domain or A subunit	K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D      Natgr_1007 GMP synthase, glutamine-hydrolyzing, C-terminal domain or B subunit	K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D      Natgr_1629 GMP synthase family protein	K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D      Natgr_2174 amidophosphoribosyltransferase	K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
D      Natgr_3664 glutamate synthase family protein	K00284 GLU; glutamate synthase (ferredoxin) [EC:1.4.7.1]
D      Natgr_3336 glucosamine--fructose-6-phosphate aminotransferase, isomerizing	K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
D      Natgr_2372 asparagine synthase (glutamine-hydrolyzing)	K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]
D      Natgr_2237 asparagine synthase (glutamine-hydrolyzing)	K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]
D      Natgr_3612 asparagine synthase (glutamine-hydrolyzing)	K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]
D      Natgr_3108 intracellular protease, PfpI family	K05520 yhbO; deglycase [EC:3.5.1.124]
D      Natgr_0902 archaeosortase A, PGF-CTERM-specific	K24447 artA; archaeosortase A [EC:3.4.22.-]
D      Natgr_3328 dipeptidase	K08659 pepDA; dipeptidase [EC:3.4.-.-]
D      Natgr_0900 CAAX amino terminal protease family	K07052 K07052; CAAX protease family protein
D      Natgr_1013 putative metal-dependent membrane protease	K07052 K07052; CAAX protease family protein
D      Natgr_1776 putative metal-dependent membrane protease	K07052 K07052; CAAX protease family protein
D      Natgr_0767 putative metal-dependent membrane protease	K07052 K07052; CAAX protease family protein
D      Natgr_2262 oligoendopeptidase F	K08602 pepF; oligoendopeptidase F [EC:3.4.24.-]
D      Natgr_3041 acetylornithine deacetylase/succinyldiaminopimelate desuccinylase-like deacylase	K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18]
D      Natgr_0988 acetylornithine deacetylase/succinyldiaminopimelate desuccinylase-like deacylase	K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18]
D      Natgr_0961 amidohydrolase	K12940 abgA; aminobenzoyl-glutamate utilization protein A
D      Natgr_1119 methionine aminopeptidase, type II	K01265 map; methionyl aminopeptidase [EC:3.4.11.18]
D      Natgr_2756 Xaa-Pro aminopeptidase	K01271 pepQ; Xaa-Pro dipeptidase [EC:3.4.13.9]
D      Natgr_3322 Xaa-Pro aminopeptidase	K01262 pepP; Xaa-Pro aminopeptidase [EC:3.4.11.9]
D      Natgr_1813 leucyl aminopeptidase (aminopeptidase T)	K19689 ampS; aminopeptidase [EC:3.4.11.-]
D      Natgr_1322 leucyl aminopeptidase (aminopeptidase T)	K19689 ampS; aminopeptidase [EC:3.4.11.-]
D      Natgr_2319 Zn-dependent carboxypeptidase	K01299 E3.4.17.19; carboxypeptidase Taq [EC:3.4.17.19]
D      Natgr_2444 Zn-dependent carboxypeptidase	K01299 E3.4.17.19; carboxypeptidase Taq [EC:3.4.17.19]
D      Natgr_0960 Zn-dependent protease with chaperone function	K03799 htpX; heat shock protein HtpX [EC:3.4.24.-]
D      Natgr_0978 Zn-dependent protease with chaperone function	K03799 htpX; heat shock protein HtpX [EC:3.4.24.-]
D      Natgr_1482 Zn-dependent protease with chaperone function	K03799 htpX; heat shock protein HtpX [EC:3.4.24.-]
D      Natgr_2141 Zn-dependent protease with chaperone function	K03799 htpX; heat shock protein HtpX [EC:3.4.24.-]
D      Natgr_2721 Zn-dependent protease with chaperone function	K03799 htpX; heat shock protein HtpX [EC:3.4.24.-]
D      Natgr_3606 Zn-dependent protease with chaperone function	K03799 htpX; heat shock protein HtpX [EC:3.4.24.-]
D      Natgr_0959 Zn-dependent protease with chaperone function	K03799 htpX; heat shock protein HtpX [EC:3.4.24.-]
D      Natgr_2356 putative Zn-dependent protease	K06974 amzA; archaemetzincin [EC:3.4.-.-]
D      Natgr_2171 putative metal-dependent protease of the PAD1/JAB1 superfamily	K20110 JAMM1; desampylase [EC:3.4.19.15]
D      Natgr_1183 putative membrane protein	K24131 prsW; protease PrsW [EC:3.4.-.-]
D      Natgr_1023 trypsin-like serine protease with C-terminal PDZ domain	K04771 degP; serine protease Do [EC:3.4.21.107]
D      Natgr_2220 trypsin-like serine protease with C-terminal PDZ domain	K04771 degP; serine protease Do [EC:3.4.21.107]
D      Natgr_3003 subtilisin-like serine protease	K01342 aprE; subtilisin [EC:3.4.21.62]
D      Natgr_3703 subtilisin-like serine protease	K01342 aprE; subtilisin [EC:3.4.21.62]
D      Natgr_3024 subtilisin-like serine protease	K14645 K14645; serine protease [EC:3.4.21.-]
D      Natgr_0086 PGF-CTERM archaeal protein-sorting signal	K17734 aprX; serine protease AprX [EC:3.4.21.-]
D      Natgr_0768 lon-related putative ATP-dependent protease	K04076 lonB; ATP-dependent Lon protease [EC:3.4.21.53]
D      Natgr_1593 signal peptidase I	K13280 SEC11; signal peptidase I [EC:3.4.21.89]
D      Natgr_1574 signal peptidase I	K13280 SEC11; signal peptidase I [EC:3.4.21.89]
D      Natgr_1964 signal peptidase I	K13280 SEC11; signal peptidase I [EC:3.4.21.89]
D      Natgr_3395 signal peptidase I	K13280 SEC11; signal peptidase I [EC:3.4.21.89]
D      Natgr_0221 putative hydrolase or acyltransferase of alpha/beta superfamily	K22369 EPHX4; epoxide hydrolase 4 [EC:3.3.-.-]
D      Natgr_2814 penicilin amidase	K01434 pac; penicillin G amidase [EC:3.5.1.11]
D      Natgr_0660 signal peptide peptidase SppA, 36K type	K04773 sppA; protease IV [EC:3.4.21.-]
D      Natgr_2427 ClpP class periplasmic serine protease	K04773 sppA; protease IV [EC:3.4.21.-]
D      Natgr_2046 putative membrane protein	K07059 K07059; rhomboid family protein
D      Natgr_3644 proteasome endopeptidase complex, archaeal, alpha subunit	K03432 psmA; proteasome alpha subunit [EC:3.4.25.1]
D      Natgr_3623 proteasome endopeptidase complex, archaeal, beta subunit	K03433 psmB; proteasome beta subunit [EC:3.4.25.1]
D      Natgr_1117 asparaginase	K13051 ASRGL1; L-asparaginase / beta-aspartyl-peptidase [EC:3.5.1.1 3.4.19.5]
D      Natgr_3671 gamma-glutamyltransferase	K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
D      Natgr_3775 gamma-glutamyltransferase	K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
C    01003 Glycosyltransferases [BR:nge01003]
D      Natgr_2226 glycosyltransferase, TIGR04182 family	K23684 aglJ; dolichol-phosphate hexosyltransferase [EC:2.4.1.-]
D      Natgr_2244 glycosyl transferase	K22844 aglG; glucosyl-dolichyl phosphate glucuronosyltransferase [EC:2.4.1.356]
D      Natgr_2243 glycosyl transferase	K23685 aglI; glycosyltransferase AglI [EC:2.4.1.-]
D      Natgr_2242 glycosyl transferase	K23685 aglI; glycosyltransferase AglI [EC:2.4.1.-]
D      Natgr_2245 oligosaccharyl transferase, archaeosortase system-associated	K21306 aglB; dolichyl-phosphooligosaccharide-protein glycotransferase [EC:2.4.99.21]
D      Natgr_3346 Trehalose-6-phosphate synthase	K16055 TPS; trehalose 6-phosphate synthase/phosphatase [EC:2.4.1.15 3.1.3.12]
D      Natgr_0581 hypothetical protein	K13693 gpgS; glucosyl-3-phosphoglycerate synthase [EC:2.4.1.266]
C    01005 Lipopolysaccharide biosynthesis proteins [BR:nge01005]
C    01011 Peptidoglycan biosynthesis and degradation proteins [BR:nge01011]
D      Natgr_0902 archaeosortase A, PGF-CTERM-specific	K24447 artA; archaeosortase A [EC:3.4.22.-]
C    01004 Lipid biosynthesis proteins [BR:nge01004]
D      Natgr_0372 dehydrogenase of unknown specificity, short-chain alcohol dehydrogenase like protein	K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D      Natgr_0427 dehydrogenase of unknown specificity, short-chain alcohol dehydrogenase like protein	K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D      Natgr_3259 dehydrogenase of unknown specificity, short-chain alcohol dehydrogenase like protein	K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D      Natgr_0594 dehydrogenase of unknown specificity, short-chain alcohol dehydrogenase like protein	K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D      Natgr_2199 short-chain alcohol dehydrogenase	K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D      Natgr_0530 acetate--CoA ligase	K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D      Natgr_0528 acetate--CoA ligase	K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D      Natgr_1583 acyl-CoA synthetase/AMP-acid ligase	K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D      Natgr_3012 acyl-CoA synthetase/AMP-acid ligase	K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D      Natgr_3230 ADP-forming acetyl coenzyme A synthetase	K24012 acdAB; acetate---CoA ligase (ADP-forming) [EC:6.2.1.13]
D      Natgr_1229 AMP-forming long-chain acyl-CoA synthetase	K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D      Natgr_1230 AMP-forming long-chain acyl-CoA synthetase	K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D      Natgr_0146 acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	K00666 K00666; fatty-acyl-CoA synthase [EC:6.2.1.-]
C    01008 Polyketide biosynthesis proteins
C    01006 Prenyltransferases [BR:nge01006]
D      Natgr_0449 geranylgeranyl pyrophosphate synthase	K13787 idsA; geranylgeranyl diphosphate synthase, type I [EC:2.5.1.1 2.5.1.10 2.5.1.29]
D      Natgr_1989 geranylgeranyl pyrophosphate synthase	K13787 idsA; geranylgeranyl diphosphate synthase, type I [EC:2.5.1.1 2.5.1.10 2.5.1.29]
D      Natgr_2570 geranylgeranyl pyrophosphate synthase	K13787 idsA; geranylgeranyl diphosphate synthase, type I [EC:2.5.1.1 2.5.1.10 2.5.1.29]
D      Natgr_3190 undecaprenyl pyrophosphate synthase	K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31]
D      Natgr_0050 phytoene/squalene synthetase	K00801 FDFT1; farnesyl-diphosphate farnesyltransferase [EC:2.5.1.21]
D      Natgr_2207 phytoene/squalene synthetase	K02291 crtB; 15-cis-phytoene synthase [EC:2.5.1.32]
D      Natgr_0210 1,4-dihydroxy-2-naphthoate octaprenyltransferase	K02548 menA; 1,4-dihydroxy-2-naphthoate polyprenyltransferase [EC:2.5.1.74]
D      Natgr_0675 protoheme IX farnesyltransferase	K02257 COX10; heme o synthase [EC:2.5.1.141]
C    01007 Amino acid related enzymes [BR:nge01007]
D      Natgr_2416 lysyl-tRNA synthetase, archaeal and spirochete	K04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6]
D      Natgr_2571 glutamyl-tRNA synthetase, archaeal and eukaryotic family	K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D      Natgr_2215 tyrosyl-tRNA synthetase	K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D      Natgr_1376 tryptophanyl-tRNA synthetase	K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D      Natgr_1730 tryptophanyl-tRNA synthetase	K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D      Natgr_3816 cysteinyl-tRNA synthetase	K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D      Natgr_0694 arginyl-tRNA synthetase	K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D      Natgr_0647 methionyl-tRNA synthetase	K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D      Natgr_1682 isoleucyl-tRNA synthetase	K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D      Natgr_0234 valyl-tRNA synthetase	K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D      Natgr_1393 leucyl-tRNA synthetase	K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D      Natgr_3390 lysyl-tRNA synthetase (class II)	K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D      Natgr_2086 aspartyl-tRNA synthetase, archaeal type	K09759 aspC; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23]
D      Natgr_2429 histidyl-tRNA synthetase	K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D      Natgr_1431 glycyl-tRNA synthetase, dimeric type	K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D      Natgr_1213 seryl-tRNA synthetase	K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D      Natgr_0967 prolyl-tRNA synthetase	K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D      Natgr_3663 prolyl-tRNA synthetase, family I	K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D      Natgr_2477 threonyl-tRNA synthetase	K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D      Natgr_2178 putative metal-dependent hydrolase related to alanyl-tRNA synthetase HxxxH domain protein	K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D      Natgr_1631 alanine--tRNA ligase/alanyl-tRNA synthetase	K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D      Natgr_2924 alanyl-tRNA synthetase	K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D      Natgr_1384 phenylalanyl-tRNA synthetase, alpha subunit	K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D      Natgr_1385 phenylalanyl-tRNA synthetase, beta subunit	K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D      Natgr_0871 aspartate/tyrosine/aromatic aminotransferase	K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D      Natgr_2941 aspartate/tyrosine/aromatic aminotransferase	K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D      Natgr_2037 aspartate/tyrosine/aromatic aminotransferase	K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D      Natgr_0253 aspartate/tyrosine/aromatic aminotransferase	K10907 K10907; aminotransferase [EC:2.6.1.-]
D      Natgr_3600 histidinol-phosphate aminotransferase	K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D      Natgr_2205 7-keto-8-aminopelargonate synthetase-like enzyme	K00652 bioF; 8-amino-7-oxononanoate synthase [EC:2.3.1.47]
D      Natgr_3684 7-keto-8-aminopelargonate synthetase-like enzyme	K00652 bioF; 8-amino-7-oxononanoate synthase [EC:2.3.1.47]
D      Natgr_1615 ornithine/acetylornithine aminotransferase	K05830 lysJ; [amino-group carrier protein]-gamma-(L-lysyl/L-ornithyl)-L-glutamate aminotransferase [EC:2.6.1.118 2.6.1.124]
D      Natgr_3371 4-aminobutyrate aminotransferase family protein	K00823 puuE; 4-aminobutyrate aminotransferase [EC:2.6.1.19]
D      Natgr_1461 glutamate-1-semialdehyde aminotransferase	K01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8]
D      Natgr_0922 branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D      Natgr_2260 branched-chain amino acid aminotransferase, group I	K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D      Natgr_3802 serine-pyruvate aminotransferase/archaeal aspartate aminotransferase	K00830 AGXT; alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase [EC:2.6.1.44 2.6.1.45 2.6.1.51]
D      Natgr_2976 putative PLP-dependent enzyme possibly involved in cell wall biogenesis	K13010 per; perosamine synthetase [EC:2.6.1.102]
C    00199 Cytochrome P450
C    00194 Photosynthesis proteins [BR:nge00194]
D      Natgr_2106 ferredoxin	K02639 petF; ferredoxin
D      Natgr_1726 ferredoxin	K02639 petF; ferredoxin
B
B  09182 Protein families: genetic information processing
C    03000 Transcription factors [BR:nge03000]
D      Natgr_1289 single-stranded DNA-binding protein	K07466 RFA1; replication factor A1
D      Natgr_0166 DNA-methyltransferase Dcm	K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D      Natgr_2595 DNA-methyltransferase Dcm	K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D      Natgr_1799 TATA-box binding protein (TBP), component of TFIID and TFIIIB	K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
D      Natgr_1810 TATA-box binding protein (TBP), component of TFIID and TFIIIB	K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
D      Natgr_3245 TATA-box binding protein (TBP), component of TFIID and TFIIIB	K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
D      Natgr_2740 transcriptional regulator	K21962 acnR; TetR/AcrR family transcriptional regulator, transcriptional repressor of aconitase
D      Natgr_2786 transcriptional regulator	K03718 asnC; Lrp/AsnC family transcriptional regulator, regulator for asnA, asnC and gidA
D      Natgr_0076 hypothetical protein	K03719 lrp; Lrp/AsnC family transcriptional regulator, leucine-responsive regulatory protein
D      Natgr_3832 transcriptional regulator	K03719 lrp; Lrp/AsnC family transcriptional regulator, leucine-responsive regulatory protein
D      Natgr_2234 hypothetical protein	K03711 fur; Fur family transcriptional regulator, ferric uptake regulator
D      Natgr_3143 transcriptional regulator	K13641 iclR; IclR family transcriptional regulator, acetate operon repressor
D      Natgr_0686 transcriptional regulator	K21827 arcR; IclR family transcriptional regulator, arginine deiminase pathway regulator
D      Natgr_2112 putative transcriptional regulator	K21903 cadC; ArsR family transcriptional regulator, lead/cadmium/zinc/bismuth-responsive transcriptional repressor
D      Natgr_0742 putative transcriptional regulator	K07721 K07721; ArsR family transcriptional regulator
D      Natgr_0933 hypothetical protein	K22206 thiR; XRE family transcriptional regulator, thiamine biosynthesis regulator
D      Natgr_2564 hypothetical protein	K22206 thiR; XRE family transcriptional regulator, thiamine biosynthesis regulator
D      Natgr_1927 Transcriptional regulator PadR-like family	K23305 gvpE; PadR family transcriptional regulator, activator of gas vesicle formation
D      Natgr_1059 putative transcriptional regulator	K10947 K10947; PadR family transcriptional regulator
D      Natgr_0090 Mn-dependent transcriptional regulator	K03709 troR; DtxR family transcriptional regulator, Mn-dependent transcriptional regulator
D      Natgr_0180 Mn-dependent transcriptional regulator	K03709 troR; DtxR family transcriptional regulator, Mn-dependent transcriptional regulator
D      Natgr_1287 Mn-dependent transcriptional regulator	K03709 troR; DtxR family transcriptional regulator, Mn-dependent transcriptional regulator
D      Natgr_0573 Mn-dependent transcriptional regulator	K03709 troR; DtxR family transcriptional regulator, Mn-dependent transcriptional regulator
D      Natgr_2213 birA, biotin-(acetyl-CoA-carboxylase) ligase	K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]
D      Natgr_3808 putative transcriptional regulator	K23356 trmB; HTH-type transcriptional regulator, sugar sensing transcriptional regulator
D      Natgr_1162 putative transcriptional regulator	K23356 trmB; HTH-type transcriptional regulator, sugar sensing transcriptional regulator
D      Natgr_0200 putative transcriptional regulator	K23356 trmB; HTH-type transcriptional regulator, sugar sensing transcriptional regulator
D      Natgr_2060 putative transcriptional regulator	K23356 trmB; HTH-type transcriptional regulator, sugar sensing transcriptional regulator
D      Natgr_2208 putative DNA binding protein	K06930 bat; HTH-type transcriptional regulator, bacterioopsin transcriptional activator and related proteins
D      Natgr_1657 response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains	K06930 bat; HTH-type transcriptional regulator, bacterioopsin transcriptional activator and related proteins
D      Natgr_3018 PAS domain S-box	K06930 bat; HTH-type transcriptional regulator, bacterioopsin transcriptional activator and related proteins
D      Natgr_1777 PAS domain S-box	K06930 bat; HTH-type transcriptional regulator, bacterioopsin transcriptional activator and related proteins
D      Natgr_0529 PAS domain S-box	K06930 bat; HTH-type transcriptional regulator, bacterioopsin transcriptional activator and related proteins
D      Natgr_1075 PAS domain S-box	K06930 bat; HTH-type transcriptional regulator, bacterioopsin transcriptional activator and related proteins
D      Natgr_0125 PAS domain S-box	K06930 bat; HTH-type transcriptional regulator, bacterioopsin transcriptional activator and related proteins
D      Natgr_0954 PAS domain S-box	K06930 bat; HTH-type transcriptional regulator, bacterioopsin transcriptional activator and related proteins
D      Natgr_1050 putative DNA binding protein	K06930 bat; HTH-type transcriptional regulator, bacterioopsin transcriptional activator and related proteins
D      Natgr_3339 PAS domain S-box	K06930 bat; HTH-type transcriptional regulator, bacterioopsin transcriptional activator and related proteins
D      Natgr_2280 putative DNA binding protein	K23348 dmsR; HTH-type transcriptional regulator, dimethyl sulfoxide reductase transcription regulator
D      Natgr_3141 putative DNA binding protein	K23348 dmsR; HTH-type transcriptional regulator, dimethyl sulfoxide reductase transcription regulator
D      Natgr_0550 putative DNA binding protein	K23348 dmsR; HTH-type transcriptional regulator, dimethyl sulfoxide reductase transcription regulator
D      Natgr_2275 putative DNA binding protein	K23348 dmsR; HTH-type transcriptional regulator, dimethyl sulfoxide reductase transcription regulator
D      Natgr_3140 putative DNA binding protein	K23348 dmsR; HTH-type transcriptional regulator, dimethyl sulfoxide reductase transcription regulator
D      Natgr_3310 putative DNA binding protein	K23348 dmsR; HTH-type transcriptional regulator, dimethyl sulfoxide reductase transcription regulator
D      Natgr_2516 putative DNA binding protein	K23348 dmsR; HTH-type transcriptional regulator, dimethyl sulfoxide reductase transcription regulator
D      Natgr_0555 putative DNA binding protein	K23348 dmsR; HTH-type transcriptional regulator, dimethyl sulfoxide reductase transcription regulator
D      Natgr_0616 putative DNA binding protein	K23348 dmsR; HTH-type transcriptional regulator, dimethyl sulfoxide reductase transcription regulator
D      Natgr_1158 DNA-binding protein, Tfx family	K09714 tfx; HTH-type transcriptional regulator, fmd operon transcriptional regulator
D      Natgr_3032 orotate phosphoribosyltransferase-like enzyme	K26599 gfcR; HTH-type transcriptional regulator, activator of D-glucose/D-fructose catabolism
D      Natgr_3204 molybdenum-binding protein	K02019 modE; molybdate transport system regulatory protein
D      Natgr_2459 putative transcriptional regulator	K07728 K07728; putative transcriptional regulator
D      Natgr_0787 putative transcriptional regulator	K07730 K07730; putative transcriptional regulator
D      Natgr_3542 putative transcriptional regulator	K07731 K07731; putative transcriptional regulator
D      Natgr_0466 putative transcriptional regulator with CopG/Arc/MetJ DNA-binding domain and metal-binding domain	K07722 nikR; CopG family transcriptional regulator, nickel-responsive regulator
D      Natgr_0394 putative transcriptional regulator with CopG/Arc/MetJ DNA-binding domain and metal-binding domain	K07722 nikR; CopG family transcriptional regulator, nickel-responsive regulator
D      Natgr_0985 putative transcriptional regulator with CopG/Arc/MetJ DNA-binding domain and metal-binding domain	K07722 nikR; CopG family transcriptional regulator, nickel-responsive regulator
D      Natgr_2811 putative transcription activator	K03707 tenA; thiaminase (transcriptional activator TenA) [EC:3.5.99.2]
C    03021 Transcription machinery [BR:nge03021]
D      Natgr_0435 transcription initiation factor TFIIIB, Brf1 subunit/transcription initiation factor TFIIB	K03124 TFIIB; transcription initiation factor TFIIB
D      Natgr_1038 transcription initiation factor TFIIIB, Brf1 subunit/transcription initiation factor TFIIB	K03124 TFIIB; transcription initiation factor TFIIB
D      Natgr_0385 transcription initiation factor TFIIIB, Brf1 subunit/transcription initiation factor TFIIB	K03124 TFIIB; transcription initiation factor TFIIB
D      Natgr_0220 transcription initiation factor TFIIIB, Brf1 subunit/transcription initiation factor TFIIB	K03124 TFIIB; transcription initiation factor TFIIB
D      Natgr_1737 transcription initiation factor TFIIIB, Brf1 subunit/transcription initiation factor TFIIB	K03124 TFIIB; transcription initiation factor TFIIB
D      Natgr_2650 hypothetical protein	K03124 TFIIB; transcription initiation factor TFIIB
D      Natgr_2544 transcription initiation factor TFIIIB, Brf1 subunit/transcription initiation factor TFIIB	K03124 TFIIB; transcription initiation factor TFIIB
D      Natgr_3557 transcription initiation factor TFIIIB, Brf1 subunit/transcription initiation factor TFIIB	K03124 TFIIB; transcription initiation factor TFIIB
D      Natgr_1799 TATA-box binding protein (TBP), component of TFIID and TFIIIB	K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
D      Natgr_1810 TATA-box binding protein (TBP), component of TFIID and TFIIIB	K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
D      Natgr_3245 TATA-box binding protein (TBP), component of TFIID and TFIIIB	K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
D      Natgr_0521 TIGR00373 family protein	K03136 TFIIE1; transcription initiation factor TFIIE subunit alpha
D      Natgr_3560 DNA/RNA helicase, superfamily II	K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
D      Natgr_1604 DNA helicase, Rad3	K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
D      Natgr_1641 DNA helicase, Rad3	K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
D      Natgr_2316 DNA-directed RNA polymerase, subunit E''	K15171 SUPT4H1; transcription elongation factor SPT4
D      Natgr_2217 ribosomal protein L24p/L26e, archaeal	K15172 SUPT5H; transcription elongation factor SPT5
D      Natgr_1203 NusA family KH domain protein	K02600 nusA; transcription termination/antitermination protein NusA
D      Natgr_1201 DNA-directed RNA polymerase subunit A''	K03041 rpoA1; DNA-directed RNA polymerase subunit A' [EC:2.7.7.6]
D      Natgr_1202 DNA-directed RNA polymerase, subunit A''''	K03042 rpoA2; DNA-directed RNA polymerase subunit A" [EC:2.7.7.6]
D      Natgr_1200 DNA-directed RNA polymerase subunit B	K03044 rpoB1; DNA-directed RNA polymerase subunit B' [EC:2.7.7.6]
D      Natgr_1199 DNA-directed RNA polymerase, beta subunit/140 kD subunit	K03045 rpoB2; DNA-directed RNA polymerase subunit B" [EC:2.7.7.6]
D      Natgr_2554 DNA-directed RNA polymerase, alpha subunit/40 kD subunit	K03047 rpoD; DNA-directed RNA polymerase subunit D [EC:2.7.7.6]
D      Natgr_2315 DNA-directed RNA polymerase subunit E'	K03049 rpoE1; DNA-directed RNA polymerase subunit E' [EC:2.7.7.6]
D      Natgr_2148 hypothetical protein	K03051 rpoF; DNA-directed RNA polymerase subunit F [EC:2.7.7.6]
D      Natgr_1198 DNA-directed RNA polymerase, subunit H, RpoH/RPB5	K03053 rpoH; DNA-directed RNA polymerase subunit H [EC:2.7.7.6]
D      Natgr_2560 DNA-directed RNA polymerase, subunit K/omega	K03055 rpoK; DNA-directed RNA polymerase subunit K [EC:2.7.7.6]
D      Natgr_0049 DNA-directed RNA polymerase, subunit L	K03056 rpoL; DNA-directed RNA polymerase subunit L [EC:2.7.7.6]
D      Natgr_2559 DNA-directed RNA polymerase, subunit N (RpoN/RPB10)	K03058 rpoN; DNA-directed RNA polymerase subunit N [EC:2.7.7.6]
D      Natgr_0844 DNA-directed RNA polymerase, subunit RPC10 (contains C4-type Zn-finger)	K03059 rpoP; DNA-directed RNA polymerase subunit P [EC:2.7.7.6]
D      Natgr_0972 transcription factor S, archaeal	K03057 tfs; transcription factor S
D      Natgr_0401 transcription factor S, archaeal	K03057 tfs; transcription factor S
C    03019 Messenger RNA biogenesis [BR:nge03019]
D      Natgr_2316 DNA-directed RNA polymerase, subunit E''	K15171 SUPT4H1; transcription elongation factor SPT4
D      Natgr_2217 ribosomal protein L24p/L26e, archaeal	K15172 SUPT5H; transcription elongation factor SPT5
D      Natgr_3747 AAA family ATPase, CDC48 subfamily	K13525 VCP; transitional endoplasmic reticulum ATPase
D      Natgr_3711 AAA family ATPase, CDC48 subfamily	K13525 VCP; transitional endoplasmic reticulum ATPase
D      Natgr_2057 putative translation factor pelota	K06965 PELO; protein pelota
D      Natgr_2004 peptide chain release factor 1	K03265 ETF1; peptide chain release factor subunit 1
D      Natgr_0889 translation elongation factor EF-1 alpha	K03231 EEF1A; elongation factor 1-alpha
D      Natgr_2849 GTPase	K03231 EEF1A; elongation factor 1-alpha
D      Natgr_2569 putative hydrolase of the metallo-beta-lactamase superfamily	K12574 rnj; ribonuclease J [EC:3.1.-.-]
D      Natgr_2730 exoribonuclease R	K12573 rnr; ribonuclease R [EC:3.1.13.1]
D      Natgr_2561 phosphopyruvate hydratase	K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D      Natgr_3218 chaperone protein DnaK	K04043 dnaK; molecular chaperone DnaK
D      Natgr_1677 DNA/RNA helicase, superfamily II	K03725 K03725; putative ATP-dependent RNA helicase [EC:5.6.2.-]
C    03041 Spliceosome
C    03011 Ribosome [BR:nge03011]
D      Natgr_0940 ribosomal protein S3AE	K02984 RP-S3Ae; small subunit ribosomal protein S3Ae
D      Natgr_0303 ribosomal protein S4E	K02987 RP-S4e; small subunit ribosomal protein S4e
D      Natgr_1925 ribosomal protein S6E (S10)	K02991 RP-S6e; small subunit ribosomal protein S6e
D      Natgr_0355 ribosomal protein S8.e	K02995 RP-S8e; small subunit ribosomal protein S8e
D      Natgr_3785 ribosomal protein S17E	K02962 RP-S17e; small subunit ribosomal protein S17e
D      Natgr_2424 ribosomal protein S19E (S16A)	K02966 RP-S19e; small subunit ribosomal protein S19e
D      Natgr_2110 ribosomal protein S24E	K02974 RP-S24e; small subunit ribosomal protein S24e
D      Natgr_0792 ribosomal protein S27E	K02978 RP-S27e; small subunit ribosomal protein S27e
D      Natgr_2109 ribosomal protein S27AE	K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae
D      Natgr_2580 ribosomal protein S28E/S33	K02979 RP-S28e; small subunit ribosomal protein S28e
D      Natgr_0314 50S ribosomal protein L4P	K02930 RP-L4e; large subunit ribosomal protein L4e
D      Natgr_2579 50S ribosomal protein L7Ae	K02936 RP-L7Ae; large subunit ribosomal protein L7Ae
D      Natgr_1667 ribosomal protein L16/L10E	K02866 RP-L10e; large subunit ribosomal protein L10e
D      Natgr_2481 ribosomal protein L15E	K02877 RP-L15e; large subunit ribosomal protein L15e
D      Natgr_2556 ribosomal protein L18E	K02883 RP-L18e; large subunit ribosomal protein L18e
D      Natgr_0297 ribosomal protein L19E	K02885 RP-L19e; large subunit ribosomal protein L19e
D      Natgr_2149 ribosomal protein L21E	K02889 RP-L21e; large subunit ribosomal protein L21e
D      Natgr_1535 ribosomal protein L31E	K02910 RP-L31e; large subunit ribosomal protein L31e
D      Natgr_0298 ribosomal protein L32E	K02912 RP-L32e; large subunit ribosomal protein L32e
D      Natgr_2078 ribosomal protein L37E	K02922 RP-L37e; large subunit ribosomal protein L37e
D      Natgr_0843 ribosomal protein L37AE/L43A	K02921 RP-L37Ae; large subunit ribosomal protein L37Ae
D      Natgr_1534 ribosomal protein L39E	K02924 RP-L39e; large subunit ribosomal protein L39e
D      Natgr_1147 ribosomal protein L40E	K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e
D      Natgr_0793 ribosomal protein L44E	K02929 RP-L44e; large subunit ribosomal protein L44e
D      Natgr_2562 ribosomal protein Sa/S2	K02967 RP-S2; small subunit ribosomal protein S2
D      Natgr_0309 ribosomal protein S3, eukaryotic/archaeal type	K02982 RP-S3; small subunit ribosomal protein S3
D      Natgr_2552 ribosomal protein S4/S9	K02986 RP-S4; small subunit ribosomal protein S4
D      Natgr_0295 ribosomal protein S5/S2	K02988 RP-S5; small subunit ribosomal protein S5
D      Natgr_1207 ribosomal protein S7/S5	K02992 RP-S7; small subunit ribosomal protein S7
D      Natgr_0300 ribosomal protein S8	K02994 RP-S8; small subunit ribosomal protein S8
D      Natgr_2558 archaeal ribosomal protein S9P	K02996 RP-S9; small subunit ribosomal protein S9
D      Natgr_0890 ribosomal protein S10/S20	K02946 RP-S10; small subunit ribosomal protein S10
D      Natgr_2553 archaeal ribosomal protein S11P	K02948 RP-S11; small subunit ribosomal protein S11
D      Natgr_1206 ribosomal protein S23	K02950 RP-S12; small subunit ribosomal protein S12
D      Natgr_2551 archaeal ribosomal protein S13P	K02952 RP-S13; small subunit ribosomal protein S13
D      Natgr_0301 ribosomal protein S14	K02954 RP-S14; small subunit ribosomal protein S14
D      Natgr_2115 ribosomal protein S14	K02954 RP-S14; small subunit ribosomal protein S14
D      Natgr_0943 ribosomal protein S15P/S13E	K02956 RP-S15; small subunit ribosomal protein S15
D      Natgr_0306 archaeal ribosomal protein S17P	K02961 RP-S17; small subunit ribosomal protein S17
D      Natgr_0311 ribosomal protein S19/S15	K02965 RP-S19; small subunit ribosomal protein S19
D      Natgr_0239 ribosomal protein L1	K02863 RP-L1; large subunit ribosomal protein L1
D      Natgr_0312 ribosomal protein L2	K02886 RP-L2; large subunit ribosomal protein L2
D      Natgr_0315 archaeal ribosomal protein L3	K02906 RP-L3; large subunit ribosomal protein L3
D      Natgr_0302 ribosomal protein L5	K02931 RP-L5; large subunit ribosomal protein L5
D      Natgr_0299 archaeal ribosomal protein L6P	K02933 RP-L6; large subunit ribosomal protein L6
D      Natgr_0240 ribosomal protein L10	K02864 RP-L10; large subunit ribosomal protein L10
D      Natgr_2935 ribosomal protein L11	K02867 RP-L11; large subunit ribosomal protein L11
D      Natgr_2557 ribosomal protein L13, archaeal/eukaryotic	K02871 RP-L13; large subunit ribosomal protein L13
D      Natgr_0305 50S ribosomal protein L14P	K02874 RP-L14; large subunit ribosomal protein L14
D      Natgr_0293 ribosomal protein L15	K02876 RP-L15; large subunit ribosomal protein L15
D      Natgr_0296 ribosomal protein L18	K02881 RP-L18; large subunit ribosomal protein L18
D      Natgr_0310 ribosomal protein L22/L17	K02890 RP-L22; large subunit ribosomal protein L22
D      Natgr_0313 archaeal ribosomal protein L23	K02892 RP-L23; large subunit ribosomal protein L23
D      Natgr_0304 ribosomal protein L24p/L26e, archaeal/eukaryotic	K02895 RP-L24; large subunit ribosomal protein L24
D      Natgr_0308 ribosomal protein L29	K02904 RP-L29; large subunit ribosomal protein L29
D      Natgr_0294 50S ribosomal protein L30P, archaeal	K02907 RP-L30; large subunit ribosomal protein L30
D      Natgr_0241 50S ribosomal protein L12P	K02869 RP-L12; large subunit ribosomal protein L12
D      Natgr_1541 ribosomal protein L20A (L18A)	K02944 RP-LX; large subunit ribosomal protein LX
D      Natgr_1343 5S ribosomal RNA	K01985 5SrRNA; 5S ribosomal RNA
D      Natgr_3793 5S ribosomal RNA	K01985 5SrRNA; 5S ribosomal RNA
D      Natgr_1836 5S ribosomal RNA	K01985 5SrRNA; 5S ribosomal RNA
D      Natgr_1833 16S ribosomal RNA	K01977 16SrRNA; 16S ribosomal RNA
D      Natgr_1346 16S ribosomal RNA	K01977 16SrRNA; 16S ribosomal RNA
D      Natgr_3796 16S ribosomal RNA	K01977 16SrRNA; 16S ribosomal RNA
D      Natgr_3794 23S ribosomal RNA	K01980 23SrRNA; 23S ribosomal RNA
D      Natgr_1835 23S ribosomal RNA	K01980 23SrRNA; 23S ribosomal RNA
D      Natgr_1344 23S ribosomal RNA	K01980 23SrRNA; 23S ribosomal RNA
C    03009 Ribosome biogenesis [BR:nge03009]
D      Natgr_0189 rRNA biogenesis protein	K14564 NOP56; nucleolar protein 56
D      Natgr_0145 rRNA pseudouridine synthase, putative	K11131 DKC1; H/ACA ribonucleoprotein complex subunit 4 [EC:5.4.99.-]
D      Natgr_0790 putative Zn-ribbon RNA-binding protein	K11130 NOP10; H/ACA ribonucleoprotein complex subunit 3
D      Natgr_1733 KH domain protein	K06961 KRR1; ribosomal RNA assembly protein
D      Natgr_1728 serine/threonine protein kinase involved in cell cycle control	K07178 RIOK1; RIO kinase 1 [EC:2.7.11.1]
D      Natgr_2483 RIO-like serine/threonine protein kinase fused to N-terminal HTH domain protein	K07179 RIOK2; RIO kinase 2 [EC:2.7.11.1]
D      Natgr_3599 putative nucleoside kinase, CMP and AMP kinase	K18532 AK6; adenylate kinase [EC:2.7.4.3]
D      Natgr_1148 hypothetical protein	K09140 TSR3; rRNA small subunit aminocarboxypropyltransferase [EC:2.5.1.157]
D      Natgr_2360 putative ATPase, Rnase L inhibitor (RLI) like protein	K06174 ABCE1; ATP-binding cassette, sub-family E, member 1
D      Natgr_2027 putative GTPase	K06943 NOG1; nucleolar GTP-binding protein
D      Natgr_0307 RNase P/RNase MRP subunit p29	K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5]
D      Natgr_3643 RNase P/RNase MRP subunit POP5	K03537 POP5; ribonuclease P/MRP protein subunit POP5 [EC:3.1.26.5]
D      Natgr_3641 RNase P/RNase MRP subunit p30	K03539 RPP1; ribonuclease P/MRP protein subunit RPP1 [EC:3.1.26.5]
D      Natgr_1536 translation initiation factor eIF-6, putative	K03264 EIF6; translation initiation factor 6
D      Natgr_1483 NMD protein affecting ribosome stability and mRNA decay	K07562 NMD3; 60S ribosomal export protein NMD3
D      Natgr_3648 rRNA metabolism protein, SBDS family	K14574 SDO1; ribosome maturation protein SDO1
D      Natgr_3747 AAA family ATPase, CDC48 subfamily	K13525 VCP; transitional endoplasmic reticulum ATPase
D      Natgr_3711 AAA family ATPase, CDC48 subfamily	K13525 VCP; transitional endoplasmic reticulum ATPase
D      Natgr_1595 small GTP-binding protein domain protein	K03595 era; GTPase
D      Natgr_0188 fibrillarin-like rRNA methylase	K04795 flpA; fibrillarin-like pre-rRNA processing protein
D      Natgr_2579 50S ribosomal protein L7Ae	K02936 RP-L7Ae; large subunit ribosomal protein L7Ae
D      Natgr_3821 RNA-binding protein involved in rRNA processing	K07569 gar1; RNA-binding protein
D      Natgr_1203 NusA family KH domain protein	K02600 nusA; transcription termination/antitermination protein NusA
D      Natgr_2145 dimethyladenosine transferase	K02528 ksgA; 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase [EC:2.1.1.182]
D      Natgr_1492 23S rRNA methylase	K02427 rlmE; 23S rRNA (uridine2552-2'-O)-methyltransferase [EC:2.1.1.166]
D      Natgr_1902 ribosomal-protein-alanine acetyltransferase	K03789 rimI; [ribosomal protein S18]-alanine N-acetyltransferase [EC:2.3.1.266]
D      Natgr_1666 glutathione synthase/ribosomal protein S6 modification enzyme (glutaminyl transferase)	K05844 rimK; ribosomal protein S6--L-glutamate ligase [EC:6.3.2.-]
D      Natgr_2831 bacteriocin biosynthesis docking scaffold, SagD family	K09136 ycaO; ribosomal protein S12 methylthiotransferase accessory factor
D      Natgr_0612 GTP-binding protein HflX	K03665 hflX; GTPase
D      Natgr_3650 GTP-binding protein HflX	K03665 hflX; GTPase
D      Natgr_1401 Sua5/YciO/YrdC/YwlC family protein	K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D      Natgr_0622 putative RNA-binding protein containing KH domain, possibly ribosomal protein	K07574 yhbY; RNA-binding protein
D      Natgr_2881 putative GTPase, probable translation factor	K06942 ychF; ribosome-binding ATPase
D      Natgr_3576 putative GTPase, probable translation factor	K06942 ychF; ribosome-binding ATPase
D      Natgr_1182 Protein of unknown function (DUF402)	K22469 fau-1; probable ribonuclease FAU-1 [EC:3.1.26.-]
C    03016 Transfer RNA biogenesis [BR:nge03016]
D      Natgr_0307 RNase P/RNase MRP subunit p29	K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5]
D      Natgr_3643 RNase P/RNase MRP subunit POP5	K03537 POP5; ribonuclease P/MRP protein subunit POP5 [EC:3.1.26.5]
D      Natgr_3641 RNase P/RNase MRP subunit p30	K03539 RPP1; ribonuclease P/MRP protein subunit RPP1 [EC:3.1.26.5]
D      Natgr_0621 RNase P subunit RPR2	K03540 RPR2; ribonuclease P protein subunit RPR2 [EC:3.1.26.5]
D      Natgr_1807 ribonuclease Z	K00784 rnz; ribonuclease Z [EC:3.1.26.11]
D      Natgr_2668 hypothetical protein	K14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]
D      Natgr_2667 hypothetical protein	K24956 ZBTB8OS; protein archease
D      Natgr_0889 translation elongation factor EF-1 alpha	K03231 EEF1A; elongation factor 1-alpha
D      Natgr_2849 GTPase	K03231 EEF1A; elongation factor 1-alpha
D      Natgr_2571 glutamyl-tRNA synthetase, archaeal and eukaryotic family	K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D      Natgr_0967 prolyl-tRNA synthetase	K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D      Natgr_3663 prolyl-tRNA synthetase, family I	K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D      Natgr_1682 isoleucyl-tRNA synthetase	K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D      Natgr_1393 leucyl-tRNA synthetase	K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D      Natgr_0647 methionyl-tRNA synthetase	K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D      Natgr_0694 arginyl-tRNA synthetase	K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D      Natgr_3390 lysyl-tRNA synthetase (class II)	K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D      Natgr_2178 putative metal-dependent hydrolase related to alanyl-tRNA synthetase HxxxH domain protein	K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D      Natgr_1631 alanine--tRNA ligase/alanyl-tRNA synthetase	K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D      Natgr_2924 alanyl-tRNA synthetase	K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D      Natgr_1431 glycyl-tRNA synthetase, dimeric type	K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D      Natgr_2477 threonyl-tRNA synthetase	K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D      Natgr_1213 seryl-tRNA synthetase	K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D      Natgr_3816 cysteinyl-tRNA synthetase	K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D      Natgr_0234 valyl-tRNA synthetase	K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D      Natgr_2429 histidyl-tRNA synthetase	K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D      Natgr_1384 phenylalanyl-tRNA synthetase, alpha subunit	K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D      Natgr_1385 phenylalanyl-tRNA synthetase, beta subunit	K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D      Natgr_2215 tyrosyl-tRNA synthetase	K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D      Natgr_1376 tryptophanyl-tRNA synthetase	K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D      Natgr_1730 tryptophanyl-tRNA synthetase	K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D      Natgr_0955 hypothetical protein	K09716 dtdA; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
D      Natgr_3358 putative metal-dependent hydrolase related to alanyl-tRNA synthetase HxxxH domain protein	K07050 AARSD1; misacylated tRNA(Ala) deacylase [EC:3.1.1.-]
D      Natgr_1680 HIT family hydrolase, diadenosine tetraphosphate hydrolase	K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
D      Natgr_2883 HIT family hydrolase, diadenosine tetraphosphate hydrolase	K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
D      Natgr_1124 MiaB-like tRNA modifying enzyme	K15865 CDKAL1; threonylcarbamoyladenosine tRNA methylthiotransferase CDKAL1 [EC:2.8.4.5]
D      Natgr_2341 N2,N2-dimethylguanosine tRNA methyltransferase	K00555 TRMT1; tRNA (guanine26-N2/guanine27-N2)-dimethyltransferase [EC:2.1.1.215 2.1.1.216]
D      Natgr_0098 putative methyltransferase	K15429 TRM5; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]
D      Natgr_0973 tRNA(1-methyladenosine) methyltransferase-like methyltransferase	K07442 TRM61; tRNA (adenine57-N1/adenine58-N1)-methyltransferase catalytic subunit [EC:2.1.1.219 2.1.1.220]
D      Natgr_0728 methylase involved in ubiquinone/menaquinone biosynthesis	K15444 TRM9; tRNA (uracil-5-)-methyltransferase TRM9 [EC:2.1.1.229]
D      Natgr_2059 putative methyltransferase, YaeB/AF_0241 family	K22900 TRMO; tRNA (adenine37-N6)-methyltransferase [EC:2.1.1.-]
D      Natgr_2254 wyosine biosynthesis protein TYW1	K15449 TYW1; tRNA wybutosine-synthesizing protein 1 [EC:4.1.3.44]
D      Natgr_1484 putative methyltransferase	K07055 TRM12; tRNA wybutosine-synthesizing protein 2 [EC:2.5.1.114]
D      Natgr_2266 pseudouridylate synthase	K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D      Natgr_0939 tRNA pseudouridine synthase, TruD family	K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
D      Natgr_1022 TIGR01213 family protein	K07583 PUS10; tRNA pseudouridine synthase 10 [EC:5.4.99.25]
D      Natgr_2713 histone acetyltransferase, ELP3 family	K07739 ELP3; elongator complex protein 3 (tRNA carboxymethyluridine synthase) [EC:2.3.1.311]
D      Natgr_1401 Sua5/YciO/YrdC/YwlC family protein	K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D      Natgr_1292 CCA-adding enzyme	K07558 K07558; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72]
D      Natgr_1362 tRNA intron endonuclease	K01170 endA; tRNA-intron endonuclease, archaea type [EC:4.6.1.16]
D      Natgr_1533 2'-5' RNA ligase	K01975 thpR; RNA 2',3'-cyclic 3'-phosphodiesterase [EC:3.1.4.58]
D      Natgr_2416 lysyl-tRNA synthetase, archaeal and spirochete	K04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6]
D      Natgr_2086 aspartyl-tRNA synthetase, archaeal type	K09759 aspC; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23]
D      Natgr_1028 hypothetical protein	K16317 trmY; tRNA (pseudouridine54-N1)-methyltransferase [EC:2.1.1.257]
D      Natgr_1800 putative DNA modification methylase	K07446 trm-G10; tRNA (guanine10-N2)-dimethyltransferase [EC:2.1.1.213]
D      Natgr_0523 hypothetical protein	K07254 atrm56; tRNA (cytidine56-2'-O)-methyltransferase [EC:2.1.1.206]
D      Natgr_3617 NOL1/NOP2/sun family putative RNA methylase	K22446 K22446; tRNA (cytosine49-C5)-methyltransferase [EC:2.1.1.-]
D      Natgr_2859 putative redox protein, regulator of disulfide bond formation	K04085 tusA; tRNA 2-thiouridine synthesizing protein A [EC:2.8.1.-]
D      Natgr_0546 putative redox protein, regulator of disulfide bond formation	K04085 tusA; tRNA 2-thiouridine synthesizing protein A [EC:2.8.1.-]
D      Natgr_3800 Iron-sulfur cluster assembly accessory protein	K13628 iscA; iron-sulfur cluster assembly protein
D      Natgr_2108 metallohydrolase, glycoprotease/Kae1 family	K15904 kae1-bud32; bifunctional N6-L-threonylcarbamoyladenine synthase / protein kinase Bud32 [EC:2.3.1.234 2.7.11.1]
D      Natgr_1514 hypothetical protein	K09119 cgi121; KEOPS complex subunit Cgi121
D      Natgr_0845 hypothetical protein	K09741 pcc1; KEOPS complex subunit Pcc1
D      Natgr_0607 queuosine biosynthesis protein QueC	K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20]
D      Natgr_0609 6-pyruvoyl-tetrahydropterin synthase	K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]
D      Natgr_3299 6-pyruvoyl-tetrahydropterin synthase	K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]
D      Natgr_0608 organic radical activating enzyme	K10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3]
D      Natgr_1056 tRNA-guanine transglycosylase	K18779 tgtA; 7-cyano-7-deazaguanine tRNA-ribosyltransferase [EC:2.4.2.48]
D      Natgr_0131 thiamine biosynthesis ATP pyrophosphatase	K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]
D      Natgr_2460 putative DNA-binding protein containing a Zn-ribbon domain	K06932 tiaS; tRNA(Ile2)-agmatinylcytidine synthase [EC:6.3.4.22]
D      Natgr_2578 putative P-loop ATPase fused to an acetyltransferase	K06957 tmcA; tRNA(Met) cytidine acetyltransferase [EC:2.3.1.193]
D      Natgr_2730 exoribonuclease R	K12573 rnr; ribonuclease R [EC:3.1.13.1]
C    03012 Translation factors [BR:nge03012]
D      Natgr_1757 eukaryotic/archaeal initiation factor 1A	K03236 EIF1A; translation initiation factor 1A
D      Natgr_2196 translation initiation factor 1 (IF-1)	K03236 EIF1A; translation initiation factor 1A
D      Natgr_2056 translation initiation factor SUI1, putative, prokaryotic	K03113 EIF1; translation initiation factor 1
D      Natgr_1715 translation initiation factor eIF-1/SUI1-like protein	K03113 EIF1; translation initiation factor 1
D      Natgr_0791 translation initiation factor 2, alpha subunit (eIF-2alpha)	K03237 EIF2S1; translation initiation factor 2 subunit 1
D      Natgr_2755 translation initiation factor 2, beta subunit (eIF-2beta)/eIF-5 N-terminal domain protein	K03238 EIF2S2; translation initiation factor 2 subunit 2
D      Natgr_2313 translation initiation factor 2 subunit gamma	K03242 EIF2S3; translation initiation factor 2 subunit 3
D      Natgr_3633 translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family	K03680 EIF2B4; translation initiation factor eIF-2B subunit delta
D      Natgr_3212 translation initiation factor eIF-5A	K03263 EIF5A; translation initiation factor 5A
D      Natgr_1010 translation initiation factor aIF-2/yIF-2	K03243 EIF5B; translation initiation factor 5B
D      Natgr_1536 translation initiation factor eIF-6, putative	K03264 EIF6; translation initiation factor 6
D      Natgr_0889 translation elongation factor EF-1 alpha	K03231 EEF1A; elongation factor 1-alpha
D      Natgr_2849 GTPase	K03231 EEF1A; elongation factor 1-alpha
D      Natgr_2101 translation elongation factor aEF-1 beta	K03232 EEF1B; elongation factor 1-beta
D      Natgr_1210 translation elongation factor aEF-2	K03234 EEF2; elongation factor 2
D      Natgr_0035 diphthamide biosynthesis enzyme Dph2	K07561 DPH1; 2-(3-amino-3-carboxypropyl)histidine synthase [EC:2.5.1.108]
D      Natgr_0658 metal-binding-domain/4Fe-4S-binding-domain containing ABC transporter, ATP-binding protein	K06927 DPH6; diphthine-ammonia ligase [EC:6.3.1.14]
D      Natgr_2004 peptide chain release factor 1	K03265 ETF1; peptide chain release factor subunit 1
D      Natgr_2143 HemK-related putative methylase	K02493 hemK; release factor glutamine methyltransferase [EC:2.1.1.297]
D      Natgr_0937 peptidyl-tRNA hydrolase	K04794 PTH2; peptidyl-tRNA hydrolase, PTH2 family [EC:3.1.1.29]
C    03110 Chaperones and folding catalysts [BR:nge03110]
D      Natgr_3218 chaperone protein DnaK	K04043 dnaK; molecular chaperone DnaK
D      Natgr_1734 thermosome subunit	K22447 cct; archaeal chaperonin
D      Natgr_2334 thermosome subunit	K22447 cct; archaeal chaperonin
D      Natgr_0774 chaperonin GroEL	K22447 cct; archaeal chaperonin
D      Natgr_3217 chaperone protein DnaJ	K03686 dnaJ; molecular chaperone DnaJ
D      Natgr_0262 molecular chaperone GrpE (heat shock protein)	K03687 GRPE; molecular chaperone GrpE
D      Natgr_0705 molecular chaperone (small heat shock protein)	K13993 HSP20; HSP20 family protein
D      Natgr_1392 molecular chaperone (small heat shock protein)	K13993 HSP20; HSP20 family protein
D      Natgr_1665 molecular chaperone (small heat shock protein)	K13993 HSP20; HSP20 family protein
D      Natgr_0587 molecular chaperone (small heat shock protein)	K13993 HSP20; HSP20 family protein
D      Natgr_3208 molecular chaperone (small heat shock protein)	K13993 HSP20; HSP20 family protein
D      Natgr_1542 prefoldin alpha subunit/subunit 5	K04797 pfdA; prefoldin alpha subunit
D      Natgr_0614 prefoldin, beta subunit, archaeal	K04798 pfdB; prefoldin beta subunit
D      Natgr_1023 trypsin-like serine protease with C-terminal PDZ domain	K04771 degP; serine protease Do [EC:3.4.21.107]
D      Natgr_2220 trypsin-like serine protease with C-terminal PDZ domain	K04771 degP; serine protease Do [EC:3.4.21.107]
D      Natgr_2166 Zn finger protein HypA/HybF (possibly regulating hydrogenase expression)	K04651 hypA; hydrogenase nickel incorporation protein HypA/HybF
D      Natgr_2167 hydrogenase accessory protein HypB	K04652 hypB; hydrogenase nickel incorporation protein HypB
D      Natgr_3307 putative component of anaerobic dehydrogenase	K23349 dmsD; putative dimethyl sulfoxide reductase chaperone
D      Natgr_0554 putative component of anaerobic dehydrogenase	K23349 dmsD; putative dimethyl sulfoxide reductase chaperone
D      Natgr_2279 putative component of anaerobic dehydrogenase	K23349 dmsD; putative dimethyl sulfoxide reductase chaperone
D      Natgr_0410 putative component of anaerobic dehydrogenase	K23349 dmsD; putative dimethyl sulfoxide reductase chaperone
D      Natgr_3003 subtilisin-like serine protease	K01342 aprE; subtilisin [EC:3.4.21.62]
D      Natgr_3703 subtilisin-like serine protease	K01342 aprE; subtilisin [EC:3.4.21.62]
D      Natgr_3024 subtilisin-like serine protease	K14645 K14645; serine protease [EC:3.4.21.-]
D      Natgr_1173 peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	K03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8]
D      Natgr_1174 peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	K03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8]
D      Natgr_0135 FKBP-type peptidyl-prolyl cis-trans isomerase	K03775 slyD; FKBP-type peptidyl-prolyl cis-trans isomerase SlyD [EC:5.2.1.8]
D      Natgr_0556 thioredoxin	K03671 TXN; thioredoxin
D      Natgr_0644 thioredoxin	K03671 TXN; thioredoxin
D      Natgr_2019 thioredoxin domain-containing protein	K03671 TXN; thioredoxin
D      Natgr_3355 Thioredoxin	K03671 TXN; thioredoxin
D      Natgr_3277 thioredoxin domain-containing protein	K03671 TXN; thioredoxin
D      Natgr_0276 glutaredoxin-related protein	K07390 grxD; monothiol glutaredoxin
C    04131 Membrane trafficking [BR:nge04131]
D      Natgr_2582 nucleoside diphosphate kinase	K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
D      Natgr_3747 AAA family ATPase, CDC48 subfamily	K13525 VCP; transitional endoplasmic reticulum ATPase
D      Natgr_3711 AAA family ATPase, CDC48 subfamily	K13525 VCP; transitional endoplasmic reticulum ATPase
D      Natgr_2038 arsenite-activated ATPase ArsA	K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-]
D      Natgr_0819 arsenite-activated ATPase ArsA	K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-]
D      Natgr_1722 arsenite-activated ATPase ArsA	K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-]
D      Natgr_3580 arsenite-activated ATPase ArsA	K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-]
D      Natgr_2218 protein translocase SEC61 complex gamma subunit, archaeal and eukaryotic	K07342 SEC61G; protein transport protein SEC61 subunit gamma and related proteins
D      Natgr_2895 glyceraldehyde-3-phosphate dehydrogenase, type I	K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D      Natgr_1663 glyceraldehyde-3-phosphate dehydrogenase, type I	K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D      Natgr_0653 pyruvate kinase	K00873 PK; pyruvate kinase [EC:2.7.1.40]
D      Natgr_0889 translation elongation factor EF-1 alpha	K03231 EEF1A; elongation factor 1-alpha
D      Natgr_2849 GTPase	K03231 EEF1A; elongation factor 1-alpha
C    04121 Ubiquitin system [BR:nge04121]
D      Natgr_1147 ribosomal protein L40E	K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e
D      Natgr_2109 ribosomal protein S27AE	K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae
C    03051 Proteasome [BR:nge03051]
D      Natgr_3644 proteasome endopeptidase complex, archaeal, alpha subunit	K03432 psmA; proteasome alpha subunit [EC:3.4.25.1]
D      Natgr_3623 proteasome endopeptidase complex, archaeal, beta subunit	K03433 psmB; proteasome beta subunit [EC:3.4.25.1]
D      Natgr_0854 26S proteasome subunit P45 family	K03420 psmR; proteasome regulatory subunit
D      Natgr_1970 26S proteasome subunit P45 family	K03420 psmR; proteasome regulatory subunit
C    03032 DNA replication proteins [BR:nge03032]
D      Natgr_1289 single-stranded DNA-binding protein	K07466 RFA1; replication factor A1
D      Natgr_1811 ribonuclease HI	K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D      Natgr_2543 ribonuclease HI	K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D      Natgr_1476 DNA polymerase sliding clamp subunit	K04802 PCNA; proliferating cell nuclear antigen
D      Natgr_2659 Proliferating cell nuclear antigen, N-terminal domain protein	K04802 PCNA; proliferating cell nuclear antigen
D      Natgr_2069 DNA/RNA helicase, superfamily I	K10742 DNA2; DNA replication ATP-dependent helicase/nuclease Dna2 [EC:5.6.2.3 3.1.-.-]
D      Natgr_0722 flap structure-specific endonuclease	K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D      Natgr_0319 ATP-dependent DNA ligase I	K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
D      Natgr_0166 DNA-methyltransferase Dcm	K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D      Natgr_2595 DNA-methyltransferase Dcm	K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D      Natgr_0790 putative Zn-ribbon RNA-binding protein	K11130 NOP10; H/ACA ribonucleoprotein complex subunit 3
D      Natgr_0145 rRNA pseudouridine synthase, putative	K11131 DKC1; H/ACA ribonucleoprotein complex subunit 4 [EC:5.4.99.-]
D      Natgr_3187 DNA primase	K02316 dnaG; DNA primase [EC:2.7.7.101]
D      Natgr_0001 orc1/cdc6 family replication initiation protein	K10725 cdc6A; archaeal cell division control protein 6
D      Natgr_1594 orc1/cdc6 family replication initiation protein	K10725 cdc6A; archaeal cell division control protein 6
D      Natgr_1500 orc1/cdc6 family replication initiation protein	K10725 cdc6A; archaeal cell division control protein 6
D      Natgr_3475 Cdc6-related protein, AAA superfamily ATPase	K10725 cdc6A; archaeal cell division control protein 6
D      Natgr_1885 Cdc6-related protein, AAA superfamily ATPase	K10725 cdc6A; archaeal cell division control protein 6
D      Natgr_1831 Cdc6-related protein, AAA superfamily ATPase	K10725 cdc6A; archaeal cell division control protein 6
D      Natgr_1738 putative ATPase involved in replication control, Cdc46/Mcm family	K10726 mcm; replicative DNA helicase Mcm [EC:5.6.2.3]
D      Natgr_3416 putative ATPase involved in replication control, Cdc46/Mcm family	K10726 mcm; replicative DNA helicase Mcm [EC:5.6.2.3]
D      Natgr_3532 putative ATPase involved in replication control, Cdc46/Mcm family	K10726 mcm; replicative DNA helicase Mcm [EC:5.6.2.3]
D      Natgr_3709 DNA primase, eukaryotic-type, small subunit, putative	K02683 priS; DNA primase small subunit [EC:2.7.7.102]
D      Natgr_1479 DNA primase, large subunit	K18882 priL; DNA primase large subunit
D      Natgr_3710 hypothetical protein	K09723 ginS; DNA replication factor GINS
D      Natgr_1020 ribonuclease H, mammalian HI/archaeal HII subfamily	K03470 rnhB; ribonuclease HII [EC:3.1.26.4]
D      Natgr_1725 DNA ligase, NAD-dependent	K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D      Natgr_0568 DNA polymerase elongation subunit (family B)	K02319 pol; DNA polymerase, archaea type [EC:2.7.7.7]
D      Natgr_1449 DNA polymerase type II, large subunit	K02322 polC; DNA polymerase II large subunit [EC:2.7.7.7]
D      Natgr_1592 archaeal DNA polymerase II, small subunit/DNA polymerase delta, subunit B	K02323 polB; DNA polymerase II small subunit [EC:2.7.7.7]
D      Natgr_3497 AAA ATPase	K04800 rfcL; replication factor C large subunit
D      Natgr_1805 DNA polymerase III, gamma/tau subunit	K04801 rfcS; replication factor C small subunit
D      Natgr_1637 DNA polymerase III, gamma/tau subunit	K04801 rfcS; replication factor C small subunit
D      Natgr_0150 site-specific DNA methylase	K06223 dam; DNA adenine methylase [EC:2.1.1.72]
D      Natgr_0183 DNA gyrase, A subunit	K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
D      Natgr_0184 DNA gyrase, B subunit	K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
D      Natgr_0388 DNA topoisomerase VI, subunit A	K03166 top6A; DNA topoisomerase VI subunit A [EC:5.6.2.2]
D      Natgr_0389 DNA topoisomerase VI, B subunit	K03167 top6B; DNA topoisomerase VI subunit B [EC:5.6.2.2]
D      Natgr_0834 topoisomerase IA	K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
D      Natgr_1363 hypothetical protein	K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
C    03036 Chromosome and associated proteins [BR:nge03036]
D      Natgr_0166 DNA-methyltransferase Dcm	K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D      Natgr_2595 DNA-methyltransferase Dcm	K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D      Natgr_0316 hypothetical protein	K09142 SPOUT1; methyltransferase [EC:2.1.1.-]
D      Natgr_1290 histones H3 and H4	K24450 hmf; DNA-binding protein
D      Natgr_3223 DNA-binding ferritin-like protein (oxidative damage protectant)	K04047 dps; starvation-inducible DNA-binding protein
D      Natgr_0076 hypothetical protein	K03719 lrp; Lrp/AsnC family transcriptional regulator, leucine-responsive regulatory protein
D      Natgr_3832 transcriptional regulator	K03719 lrp; Lrp/AsnC family transcriptional regulator, leucine-responsive regulatory protein
D      Natgr_3009 chromosome segregation protein SMC	K03529 smc; chromosome segregation protein
D      Natgr_3008 hypothetical protein	K05896 scpA; segregation and condensation protein A
D      Natgr_0956 cell division protein FtsZ	K03531 ftsZ; cell division protein FtsZ
D      Natgr_2506 cell division protein FtsZ	K03531 ftsZ; cell division protein FtsZ
D      Natgr_1339 ATPase involved in chromosome partitioning	K03609 minD; septum site-determining protein MinD
D      Natgr_2003 cell division ATPase MinD, archaeal	K03609 minD; septum site-determining protein MinD
D      Natgr_1957 ATPase involved in chromosome partitioning	K03496 parA; chromosome partitioning protein
D      Natgr_2769 ATPase involved in chromosome partitioning	K03496 parA; chromosome partitioning protein
D      Natgr_3499 site-specific recombinase XerD	K04763 xerD; integrase/recombinase XerD
D      Natgr_0270 ATPase involved in chromosome partitioning	K03593 mrp; ATP-binding protein involved in chromosome partitioning
D      Natgr_3142 putative metal-sulfur cluster biosynthetic enzyme	K03593 mrp; ATP-binding protein involved in chromosome partitioning
D      Natgr_3377 ATPase involved in chromosome partitioning	K03593 mrp; ATP-binding protein involved in chromosome partitioning
D      Natgr_3308 ATPase involved in chromosome partitioning	K03593 mrp; ATP-binding protein involved in chromosome partitioning
C    03400 DNA repair and recombination proteins [BR:nge03400]
D      Natgr_0765 methylated DNA-protein cysteine methyltransferase	K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D      Natgr_0011 deoxyribodipyrimidine photolyase	K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D      Natgr_3781 A/G-specific DNA glycosylase	K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
D      Natgr_0381 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase	K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18]
D      Natgr_0453 endonuclease III	K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D      Natgr_2535 putative endoIII-related endonuclease	K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D      Natgr_1476 DNA polymerase sliding clamp subunit	K04802 PCNA; proliferating cell nuclear antigen
D      Natgr_2659 Proliferating cell nuclear antigen, N-terminal domain protein	K04802 PCNA; proliferating cell nuclear antigen
D      Natgr_0722 flap structure-specific endonuclease	K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D      Natgr_0319 ATP-dependent DNA ligase I	K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
D      Natgr_3560 DNA/RNA helicase, superfamily II	K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
D      Natgr_1604 DNA helicase, Rad3	K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
D      Natgr_1641 DNA helicase, Rad3	K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
D      Natgr_1289 single-stranded DNA-binding protein	K07466 RFA1; replication factor A1
D      Natgr_3661 ADP-ribose pyrophosphatase	K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D      Natgr_0735 ADP-ribose pyrophosphatase	K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D      Natgr_1999 ADP-ribose pyrophosphatase	K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D      Natgr_2366 deoxycytidine deaminase	K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D      Natgr_2666 deoxyribodipyrimidine photolyase-related protein	K06876 phrB; (6-4)DNA photolyase [EC:4.1.99.13]
D      Natgr_2015 uracil-DNA glycosylase, family 4	K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
D      Natgr_3379 uracil-DNA glycosylase	K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
D      Natgr_0395 uracil-DNA glycosylase	K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
D      Natgr_0479 HhH-GPD superfamily base excision DNA repair protein	K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
D      Natgr_2497 apurinic endonuclease APN1	K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
D      Natgr_2045 deoxyinosine 3'endonuclease (endonuclease V)	K05982 E3.1.21.7; deoxyribonuclease V [EC:3.1.21.7]
D      Natgr_1455 single-stranded DNA-specific exonuclease	K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D      Natgr_1725 DNA ligase, NAD-dependent	K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D      Natgr_2117 excinuclease ABC, A subunit	K03701 uvrA; excinuclease ABC subunit A
D      Natgr_1510 excinuclease ABC, B subunit	K03702 uvrB; excinuclease ABC subunit B
D      Natgr_1717 excinuclease ABC, C subunit	K03703 uvrC; excinuclease ABC subunit C
D      Natgr_1189 DNA/RNA helicase, superfamily I	K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D      Natgr_2401 DNA mismatch repair protein MutS	K03555 mutS; DNA mismatch repair protein MutS
D      Natgr_3084 DNA mismatch repair protein MutS	K03555 mutS; DNA mismatch repair protein MutS
D      Natgr_2102 MutS domain V	K07456 mutS2; DNA mismatch repair protein MutS2
D      Natgr_1505 mismatch repair ATPase (MutS family)	K07456 mutS2; DNA mismatch repair protein MutS2
D      Natgr_2724 DNA mismatch repair protein MutL	K03572 mutL; DNA mismatch repair protein MutL
D      Natgr_0150 site-specific DNA methylase	K06223 dam; DNA adenine methylase [EC:2.1.1.72]
D      Natgr_0564 ATPase involved in DNA repair	K03546 sbcC; DNA repair protein SbcC/Rad50
D      Natgr_2626 ATPase involved in DNA repair	K03546 sbcC; DNA repair protein SbcC/Rad50
D      Natgr_2625 DNA repair exonuclease	K03547 sbcD; DNA repair protein SbcD/Mre11
D      Natgr_0563 DNA repair exonuclease	K03547 sbcD; DNA repair protein SbcD/Mre11
D      Natgr_3461 CRISPR-associated endonuclease Cas1	K15342 cas1; CRISP-associated protein Cas1
D      Natgr_1768 DNA repair and recombination protein RadA	K04483 radA; DNA repair protein RadA
D      Natgr_3753 RecA/RadA recombinase	K04484 radB; DNA repair protein RadB
D      Natgr_1775 Holliday junction resolvase	K03552 hjr; holliday junction resolvase [EC:3.1.21.10]
D      Natgr_1513 superfamily II helicase	K03726 helS; ATP-dependent DNA helicase [EC:5.6.2.4]
D      Natgr_0183 DNA gyrase, A subunit	K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
D      Natgr_0184 DNA gyrase, B subunit	K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
D      Natgr_0834 topoisomerase IA	K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
D      Natgr_1363 hypothetical protein	K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
D      Natgr_0397 nucleotidyltransferase/DNA polymerase involved in DNA repair	K04479 dbh; DNA polymerase IV (archaeal DinB-like DNA polymerase) [EC:2.7.7.7]
D      Natgr_2049 DNA polymerase IV (family X)	K02347 polX; DNA polymerase (family X)
D      Natgr_2927 Lhr-like helicase	K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
D      Natgr_3284 Lhr-like helicase	K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
D      Natgr_3765 ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent	K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D      Natgr_2172 hypothetical protein	K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D      Natgr_2098 hypothetical protein	K22585 nreA; DNA repair protein NreA
C    03029 Mitochondrial biogenesis [BR:nge03029]
D      Natgr_0307 RNase P/RNase MRP subunit p29	K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5]
D      Natgr_3643 RNase P/RNase MRP subunit POP5	K03537 POP5; ribonuclease P/MRP protein subunit POP5 [EC:3.1.26.5]
D      Natgr_3641 RNase P/RNase MRP subunit p30	K03539 RPP1; ribonuclease P/MRP protein subunit RPP1 [EC:3.1.26.5]
D      Natgr_1595 small GTP-binding protein domain protein	K03595 era; GTPase
D      Natgr_2215 tyrosyl-tRNA synthetase	K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D      Natgr_1393 leucyl-tRNA synthetase	K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D      Natgr_1431 glycyl-tRNA synthetase, dimeric type	K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D      Natgr_0694 arginyl-tRNA synthetase	K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D      Natgr_0218 glutamyl-tRNA(Gln) and/or aspartyl-tRNA(Asn) amidotransferase, A subunit	K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7]
D      Natgr_3674 glutamyl-tRNA(Gln) and/or aspartyl-tRNA(Asn) amidotransferase, B subunit	K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7]
D      Natgr_0219 glutamyl-tRNA(Gln) and/or aspartyl-tRNA(Asn) amidotransferase, C subunit	K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7]
D      Natgr_3218 chaperone protein DnaK	K04043 dnaK; molecular chaperone DnaK
D      Natgr_0262 molecular chaperone GrpE (heat shock protein)	K03687 GRPE; molecular chaperone GrpE
D      Natgr_3217 chaperone protein DnaJ	K03686 dnaJ; molecular chaperone DnaJ
D      Natgr_0276 glutaredoxin-related protein	K07390 grxD; monothiol glutaredoxin
D      Natgr_0270 ATPase involved in chromosome partitioning	K03593 mrp; ATP-binding protein involved in chromosome partitioning
D      Natgr_3142 putative metal-sulfur cluster biosynthetic enzyme	K03593 mrp; ATP-binding protein involved in chromosome partitioning
D      Natgr_3377 ATPase involved in chromosome partitioning	K03593 mrp; ATP-binding protein involved in chromosome partitioning
D      Natgr_3308 ATPase involved in chromosome partitioning	K03593 mrp; ATP-binding protein involved in chromosome partitioning
D      Natgr_0675 protoheme IX farnesyltransferase	K02257 COX10; heme o synthase [EC:2.5.1.141]
D      Natgr_0392 uncharacterized protein required for cytochrome oxidase assembly	K02259 COX15; heme a synthase [EC:1.17.99.9]
D      Natgr_2386 uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems	K07152 SCO1; protein SCO1
D      Natgr_3344 uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems	K07152 SCO1; protein SCO1
B
B  09183 Protein families: signaling and cellular processes
C    02000 Transporters [BR:nge02000]
D      Natgr_1313 ABC-type multidrug transport system, ATPase and permease component	K06147 ABCB-BAC; ATP-binding cassette, subfamily B, bacterial
D      Natgr_2390 ABC-type molybdate transport system, periplasmic component	K15495 wtpA; molybdate/tungstate transport system substrate-binding protein
D      Natgr_2389 NifC-like ABC-type porter	K15496 wtpB; molybdate/tungstate transport system permease protein
D      Natgr_2388 ABC-type spermidine/putrescine transport system, ATPase component	K15497 wtpC; molybdate/tungstate transport system ATP-binding protein [EC:7.3.2.5 7.3.2.6]
D      Natgr_3201 ABC-type tungstate transport system, permease component	K05772 tupA; tungstate transport system substrate-binding protein
D      Natgr_3202 ABC-type tungstate transport system, periplasmic component	K05773 tupB; tungstate transport system permease protein
D      Natgr_3203 ABC-type polar amino acid transport system, ATPase component	K06857 tupC; tungstate transport system ATP-binding protein [EC:7.3.2.6]
D      Natgr_1602 ABC-type Fe3+ transport system, periplasmic component	K02012 afuA; iron(III) transport system substrate-binding protein
D      Natgr_1601 ABC-type Fe3+ transport system, permease component	K02011 afuB; iron(III) transport system permease protein
D      Natgr_0730 ABC-type spermidine/putrescine transport system, ATPase component	K02010 afuC; iron(III) transport system ATP-binding protein [EC:7.2.2.7]
D      Natgr_1587 ABC transporter periplasmic binding protein, thiB subfamily	K02064 thiB; thiamine transport system substrate-binding protein
D      Natgr_2373 ABC transporter periplasmic binding protein, thiB subfamily	K02064 thiB; thiamine transport system substrate-binding protein
D      Natgr_2375 ABC-type Fe3+ transport system, permease component	K02063 thiP; thiamine transport system permease protein
D      Natgr_2376 ABC-type spermidine/putrescine transport system, ATPase component	K02062 thiQ; thiamine transport system ATP-binding protein [EC:7.6.2.15]
D      Natgr_2534 spermidine/putrescine-binding periplasmic protein	K11069 potD; spermidine/putrescine transport system substrate-binding protein
D      Natgr_2531 ABC-type spermidine/putrescine transport system, permease component II	K11070 potC; spermidine/putrescine transport system permease protein
D      Natgr_2532 ABC-type spermidine/putrescine transport system, permease component I	K11071 potB; spermidine/putrescine transport system permease protein
D      Natgr_2533 ABC-type spermidine/putrescine transport system, ATPase component	K11072 potA; spermidine/putrescine transport system ATP-binding protein [EC:7.6.2.11]
D      Natgr_1628 ATPase component of ABC-type sugar transporter	K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
D      Natgr_3625 ATPase component of ABC-type sugar transporter	K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
D      Natgr_3628 ABC-type sugar transport system, periplasmic component	K17315 gtsA; glucose/mannose transport system substrate-binding protein
D      Natgr_3627 permease component of ABC-type sugar transporter	K17316 gtsB; glucose/mannose transport system permease protein
D      Natgr_3626 ABC-type sugar transport system, permease component	K17317 gtsC; glucose/mannose transport system permease protein
D      Natgr_1622 ABC-type sugar transport system, periplasmic component	K02027 ABC.MS.S; multiple sugar transport system substrate-binding protein
D      Natgr_1627 permease component of ABC-type sugar transporter	K02025 ABC.MS.P; multiple sugar transport system permease protein
D      Natgr_1626 ABC-type sugar transport system, permease component	K02026 ABC.MS.P1; multiple sugar transport system permease protein
D      Natgr_0756 ABC-type phosphate transport system, periplasmic component	K02040 pstS; phosphate transport system substrate-binding protein
D      Natgr_0352 ABC-type phosphate transport system, periplasmic component	K02040 pstS; phosphate transport system substrate-binding protein
D      Natgr_2800 ABC-type phosphate transport system, periplasmic component	K02040 pstS; phosphate transport system substrate-binding protein
D      Natgr_0755 phosphate ABC transporter, permease protein PstC	K02037 pstC; phosphate transport system permease protein
D      Natgr_0351 phosphate ABC transporter, permease protein PstC	K02037 pstC; phosphate transport system permease protein
D      Natgr_2799 phosphate ABC transporter, permease protein PstC	K02037 pstC; phosphate transport system permease protein
D      Natgr_0754 ABC-type phosphate transport system, permease component	K02038 pstA; phosphate transport system permease protein
D      Natgr_0350 phosphate ABC transporter, permease protein PstA	K02038 pstA; phosphate transport system permease protein
D      Natgr_2798 phosphate ABC transporter, permease protein PstA	K02038 pstA; phosphate transport system permease protein
D      Natgr_0349 phosphate ABC transporter, ATP-binding protein	K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]
D      Natgr_2797 phosphate ABC transporter, ATP-binding protein	K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]
D      Natgr_0753 ABC-type phosphate transport system, ATPase component	K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]
D      Natgr_1367 ABC-type phosphate/phosphonate transport system, periplasmic component	K02044 phnD; phosphonate transport system substrate-binding protein
D      Natgr_2792 phosphate/phosphite/phosphonate ABC transporters, periplasmic binding protein	K02044 phnD; phosphonate transport system substrate-binding protein
D      Natgr_1365 phosphonate ABC transporter, permease protein PhnE	K02042 phnE; phosphonate transport system permease protein
D      Natgr_2789 phosphonate ABC transporter, permease protein PhnE	K02042 phnE; phosphonate transport system permease protein
D      Natgr_2790 phosphonate ABC transporter, permease protein PhnE	K02042 phnE; phosphonate transport system permease protein
D      Natgr_1366 phosphonate ABC transporter, ATP-binding protein	K02041 phnC; phosphonate transport system ATP-binding protein [EC:7.3.2.2]
D      Natgr_2791 phosphonate ABC transporter, ATP-binding protein	K02041 phnC; phosphonate transport system ATP-binding protein [EC:7.3.2.2]
D      Natgr_1238 ABC-type branched-chain amino acid transport system, periplasmic component	K01999 livK; branched-chain amino acid transport system substrate-binding protein
D      Natgr_2125 ABC-type branched-chain amino acid transport system, periplasmic component	K01999 livK; branched-chain amino acid transport system substrate-binding protein
D      Natgr_1204 ABC-type branched-chain amino acid transport system, periplasmic component	K01999 livK; branched-chain amino acid transport system substrate-binding protein
D      Natgr_0884 ABC-type branched-chain amino acid transport system, periplasmic component	K01999 livK; branched-chain amino acid transport system substrate-binding protein
D      Natgr_1991 ABC-type branched-chain amino acid transport system, periplasmic component	K01999 livK; branched-chain amino acid transport system substrate-binding protein
D      Natgr_0880 branched-chain amino acid ABC-type transport system, permease component	K01997 livH; branched-chain amino acid transport system permease protein
D      Natgr_1239 branched-chain amino acid ABC-type transport system, permease component	K01997 livH; branched-chain amino acid transport system permease protein
D      Natgr_0881 ABC-type branched-chain amino acid transport system, permease component	K01998 livM; branched-chain amino acid transport system permease protein
D      Natgr_1240 ABC-type branched-chain amino acid transport systems, ATPase component	K01995 livG; branched-chain amino acid transport system ATP-binding protein
D      Natgr_0882 ABC-type branched-chain amino acid transport systems, ATPase component	K01995 livG; branched-chain amino acid transport system ATP-binding protein
D      Natgr_0883 ABC-type branched-chain amino acid transport systems, ATPase component	K01996 livF; branched-chain amino acid transport system ATP-binding protein
D      Natgr_1241 ABC-type branched-chain amino acid transport systems, ATPase component	K01996 livF; branched-chain amino acid transport system ATP-binding protein
D      Natgr_0618 extracellular solute-binding protein, family 5	K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D      Natgr_0620 extracellular solute-binding protein, family 5	K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D      Natgr_1149 extracellular solute-binding protein, family 5	K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D      Natgr_1440 ABC-type dipeptide transport system, periplasmic component	K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D      Natgr_1700 ABC-type dipeptide transport system, periplasmic component	K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D      Natgr_3314 ABC-type dipeptide transport system, periplasmic component	K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D      Natgr_3734 ABC-type dipeptide transport system, periplasmic component	K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D      Natgr_3739 ABC-type dipeptide transport system, periplasmic component	K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D      Natgr_0009 extracellular solute-binding protein, family 5	K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D      Natgr_1447 ABC-type dipeptide transport system, periplasmic component	K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D      Natgr_0807 ABC-type dipeptide/oligopeptide/nickel transport system, permease component	K02033 ABC.PE.P; peptide/nickel transport system permease protein
D      Natgr_0798 ABC-type dipeptide/oligopeptide/nickel transport system, permease component	K02033 ABC.PE.P; peptide/nickel transport system permease protein
D      Natgr_1150 ABC-type dipeptide/oligopeptide/nickel transport system, permease component	K02033 ABC.PE.P; peptide/nickel transport system permease protein
D      Natgr_1439 ABC-type dipeptide/oligopeptide/nickel transport system, permease component	K02033 ABC.PE.P; peptide/nickel transport system permease protein
D      Natgr_1446 ABC-type dipeptide/oligopeptide/nickel transport system, permease component	K02033 ABC.PE.P; peptide/nickel transport system permease protein
D      Natgr_1699 ABC-type dipeptide/oligopeptide/nickel transport system, permease component	K02033 ABC.PE.P; peptide/nickel transport system permease protein
D      Natgr_3311 ABC-type dipeptide/oligopeptide/nickel transport system, permease component	K02033 ABC.PE.P; peptide/nickel transport system permease protein
D      Natgr_3735 ABC-type dipeptide/oligopeptide/nickel transport system, permease component	K02033 ABC.PE.P; peptide/nickel transport system permease protein
D      Natgr_3740 ABC-type dipeptide/oligopeptide/nickel transport system, permease component	K02033 ABC.PE.P; peptide/nickel transport system permease protein
D      Natgr_0808 ABC-type dipeptide/oligopeptide/nickel transport system, permease component	K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D      Natgr_0799 ABC-type dipeptide/oligopeptide/nickel transport system, permease component	K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D      Natgr_1151 ABC-type dipeptide/oligopeptide/nickel transport system, permease component	K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D      Natgr_1438 ABC-type dipeptide/oligopeptide/nickel transport system, permease component	K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D      Natgr_1445 ABC-type dipeptide/oligopeptide/nickel transport system, permease component	K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D      Natgr_1698 ABC-type dipeptide/oligopeptide/nickel transport system, permease component	K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D      Natgr_3312 ABC-type dipeptide/oligopeptide/nickel transport system, permease component	K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D      Natgr_3741 ABC-type dipeptide/oligopeptide/nickel transport system, permease component	K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D      Natgr_3736 ABC-type dipeptide/oligopeptide/nickel transport system, permease component	K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D      Natgr_3737 oligopeptide/dipeptide ABC transporter, ATP-binding protein	K02031 ddpD; peptide/nickel transport system ATP-binding protein
D      Natgr_3313 oligopeptide/dipeptide ABC transporter, ATP-binding protein	K02031 ddpD; peptide/nickel transport system ATP-binding protein
D      Natgr_3742 oligopeptide/dipeptide ABC transporter, ATP-binding protein	K02031 ddpD; peptide/nickel transport system ATP-binding protein
D      Natgr_1444 oligopeptide/dipeptide ABC transporter, ATP-binding protein	K02031 ddpD; peptide/nickel transport system ATP-binding protein
D      Natgr_1697 oligopeptide/dipeptide ABC transporter, ATP-binding protein	K02031 ddpD; peptide/nickel transport system ATP-binding protein
D      Natgr_1152 oligopeptide/dipeptide ABC transporter, ATP-binding protein	K02031 ddpD; peptide/nickel transport system ATP-binding protein
D      Natgr_1437 oligopeptide/dipeptide ABC transporter, ATP-binding protein	K02031 ddpD; peptide/nickel transport system ATP-binding protein
D      Natgr_0800 oligopeptide/dipeptide ABC transporter, ATP-binding protein	K02031 ddpD; peptide/nickel transport system ATP-binding protein
D      Natgr_0809 oligopeptide/dipeptide ABC transporter, ATP-binding protein	K02031 ddpD; peptide/nickel transport system ATP-binding protein
D      Natgr_1443 oligopeptide/dipeptide ABC transporter, ATP-binding protein	K02032 ddpF; peptide/nickel transport system ATP-binding protein
D      Natgr_1153 oligopeptide/dipeptide ABC transporter, ATP-binding protein	K02032 ddpF; peptide/nickel transport system ATP-binding protein
D      Natgr_3738 oligopeptide/dipeptide ABC transporter, ATP-binding protein	K02032 ddpF; peptide/nickel transport system ATP-binding protein
D      Natgr_3743 oligopeptide/dipeptide ABC transporter, ATP-binding protein	K02032 ddpF; peptide/nickel transport system ATP-binding protein
D      Natgr_0810 oligopeptide/dipeptide ABC transporter, ATP-binding protein	K02032 ddpF; peptide/nickel transport system ATP-binding protein
D      Natgr_0801 oligopeptide/dipeptide ABC transporter, ATP-binding protein	K02032 ddpF; peptide/nickel transport system ATP-binding protein
D      Natgr_2284 ABC-type Fe3+-hydroxamate transport system, periplasmic component	K02016 ABC.FEV.S; iron complex transport system substrate-binding protein
D      Natgr_2433 ABC-type Fe3+-hydroxamate transport system, periplasmic component	K02016 ABC.FEV.S; iron complex transport system substrate-binding protein
D      Natgr_0984 ABC-type Fe3+-hydroxamate transport system, periplasmic component	K02016 ABC.FEV.S; iron complex transport system substrate-binding protein
D      Natgr_1043 ABC-type Fe3+-hydroxamate transport system, periplasmic component	K02016 ABC.FEV.S; iron complex transport system substrate-binding protein
D      Natgr_2286 ABC-type Fe3+-siderophore transport system, permease component	K02015 ABC.FEV.P; iron complex transport system permease protein
D      Natgr_1045 ABC-type Fe3+-siderophore transport system, permease component	K02015 ABC.FEV.P; iron complex transport system permease protein
D      Natgr_0983 ABC-type Fe3+-siderophore transport system, permease component	K02015 ABC.FEV.P; iron complex transport system permease protein
D      Natgr_1047 ABC-type cobalamin/Fe3+-siderophore transport system, ATPase component	K02013 ABC.FEV.A; iron complex transport system ATP-binding protein [EC:7.2.2.-]
D      Natgr_0982 ABC-type cobalamin/Fe3+-siderophore transport system, ATPase component	K02013 ABC.FEV.A; iron complex transport system ATP-binding protein [EC:7.2.2.-]
D      Natgr_2285 ABC-type cobalamin/Fe3+-siderophore transport system, ATPase component	K02013 ABC.FEV.A; iron complex transport system ATP-binding protein [EC:7.2.2.-]
D      Natgr_3827 ABC-type Fe3+-hydroxamate transport system, periplasmic component	K25034 btuF; cobalamin transport system substrate-binding protein
D      Natgr_3828 ABC-type Fe3+-siderophore transport system, permease component	K25027 btuC; cobalamin transport system permease protein
D      Natgr_3829 ABC-type cobalamin/Fe3+-siderophore transport system, ATPase component	K25028 btuD; cobalamin transport system ATP-binding protein [EC:7.6.2.8]
D      Natgr_0092 ABC-type metal ion transport system, periplasmic component/surface adhesin	K09815 znuA; zinc transport system substrate-binding protein
D      Natgr_3227 ABC-type metal ion transport system, periplasmic component/surface adhesin	K09815 znuA; zinc transport system substrate-binding protein
D      Natgr_0094 ABC-type Mn2+/Zn2+ transport system, permease component	K09816 znuB; zinc transport system permease protein
D      Natgr_3229 ABC-type Mn2+/Zn2+ transport system, permease component	K09816 znuB; zinc transport system permease protein
D      Natgr_0093 ATPase component of Mn/Zn ABC-type transporter	K09817 znuC; zinc transport system ATP-binding protein [EC:7.2.2.20]
D      Natgr_3228 ATPase component of Mn/Zn ABC-type transporter	K09817 znuC; zinc transport system ATP-binding protein [EC:7.2.2.20]
D      Natgr_2772 hypothetical protein	K03523 bioY; biotin transport system substrate-specific component
D      Natgr_2770 ABC-type cobalt transport system, permease component CbiQ	K16783 bioN; biotin transport system permease protein
D      Natgr_2771 ABC-type cobalt transport system, ATPase component	K16784 bioM; biotin transport system ATP-binding protein [EC:7.6.2.-]
D      Natgr_2391 hypothetical protein	K19341 nosY; Cu-processing system permease protein
D      Natgr_2392 ABC-type multidrug transport system, ATPase component	K19340 nosF; Cu-processing system ATP-binding protein
D      Natgr_2393 nitrous oxidase accessory protein	K07218 nosD; nitrous oxidase accessory protein
D      Natgr_0669 hypothetical protein	K25147 berB; beta-exotoxin I transport system permease protein
D      Natgr_0668 hypothetical protein	K25147 berB; beta-exotoxin I transport system permease protein
D      Natgr_0667 ABC-type multidrug transport system, ATPase component	K25148 berA; beta-exotoxin I transport system ATP-binding protein
D      Natgr_3136 ABC-type transport system involved in cytochrome c biogenesis, permease component	K02195 ccmC; heme exporter protein C
D      Natgr_3129 ABC-type transport system involved in cytochrome c biogenesis, permease component	K02194 ccmB; heme exporter protein B
D      Natgr_3130 ABC-type multidrug transport system, ATPase component	K02193 ccmA; heme exporter protein A [EC:7.6.2.5]
D      Natgr_0455 hypothetical protein	K01992 ABC-2.P; ABC-2 type transport system permease protein
D      Natgr_0064 hypothetical protein	K01992 ABC-2.P; ABC-2 type transport system permease protein
D      Natgr_1720 ABC-type transport system involved in multi-copper enzyme maturation, permease component	K01992 ABC-2.P; ABC-2 type transport system permease protein
D      Natgr_0559 ABC-type multidrug transport system, permease component	K01992 ABC-2.P; ABC-2 type transport system permease protein
D      Natgr_1671 ABC-type polysaccharide/polyol phosphate export systems, permease component	K01992 ABC-2.P; ABC-2 type transport system permease protein
D      Natgr_3098 ABC-type multidrug transport system, permease component	K01992 ABC-2.P; ABC-2 type transport system permease protein
D      Natgr_2815 ABC-type Na+ efflux pump, permease component	K01992 ABC-2.P; ABC-2 type transport system permease protein
D      Natgr_1407 ABC-type transport system involved in multi-copper enzyme maturation, permease component	K01992 ABC-2.P; ABC-2 type transport system permease protein
D      Natgr_0065 ABC-type multidrug transport system, ATPase component	K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D      Natgr_1408 ABC-type multidrug transport system, ATPase component	K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D      Natgr_1719 ABC-type multidrug transport system, ATPase component	K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D      Natgr_2817 ABC-type multidrug transport system, ATPase component	K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D      Natgr_3607 ABC-type multidrug transport system, ATPase component	K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D      Natgr_0454 ABC-type multidrug transport system, ATPase component	K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D      Natgr_0558 ABC-type multidrug transport system, ATPase component	K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D      Natgr_1670 ABC-type multidrug transport system, ATPase component	K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D      Natgr_3099 daunorubicin resistance ABC transporter ATP-binding subunit	K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D      Natgr_2982 ABC-type multidrug transport system, ATPase component	K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D      Natgr_0045 ABC-type transport system, involved in lipoprotein release, permease component	K02004 ABC.CD.P; putative ABC transport system permease protein
D      Natgr_1576 ABC-type antimicrobial peptide transport system, permease component	K02004 ABC.CD.P; putative ABC transport system permease protein
D      Natgr_0046 ABC-type transport system, involved in lipoprotein release, permease component	K02004 ABC.CD.P; putative ABC transport system permease protein
D      Natgr_1575 ABC-type antimicrobial peptide transport system, ATPase component	K02003 ABC.CD.A; putative ABC transport system ATP-binding protein
D      Natgr_0047 ABC-type antimicrobial peptide transport system, ATPase component	K02003 ABC.CD.A; putative ABC transport system ATP-binding protein
D      Natgr_0569 ABC-type transport system involved in Fe-S cluster assembly, ATPase component	K09013 sufC; Fe-S cluster assembly ATP-binding protein
D      Natgr_3682 anion transporter	K14445 SLC13A2_3_5; solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2/3/5
D      Natgr_0920 putative efflux protein, MATE family	K26937 dinF; MATE family, multidrug efflux pump
D      Natgr_3054 putative efflux protein, MATE family	K26937 dinF; MATE family, multidrug efflux pump
D      Natgr_1586 putative efflux protein, MATE family	K26937 dinF; MATE family, multidrug efflux pump
D      Natgr_2522 putative efflux protein, MATE family	K26937 dinF; MATE family, multidrug efflux pump
D      Natgr_0836 putative efflux protein, MATE family	K26937 dinF; MATE family, multidrug efflux pump
D      Natgr_2041 putative efflux protein, MATE family	K26937 dinF; MATE family, multidrug efflux pump
D      Natgr_1129 Kef-type K+ ransport system, predicted NAD-binding component	K10716 kch; voltage-gated potassium channel
D      Natgr_2916 Kef-type K+ ransport system, predicted NAD-binding component	K10716 kch; voltage-gated potassium channel
D      Natgr_1462 ammonia permease	K03320 amt; ammonium transporter, Amt family
D      Natgr_2093 uncharacterized protein containing a von Willebrand factor type A (vWA) domain	K07114 yfbK; Ca-activated chloride channel homolog
D      Natgr_3807 small-conductance mechanosensitive channel	K03442 mscS; small conductance mechanosensitive channel
D      Natgr_1223 Mg2+ transporter MgtE	K06213 mgtE; magnesium transporter
D      Natgr_1220 cation transporter	K07244 K07244; mgtE-like transporter
D      Natgr_1221 cation transporter	K07244 K07244; mgtE-like transporter
D      Natgr_1225 protein CrcB	K06199 crcB; fluoride exporter
D      Natgr_1226 Integral membrane protein possibly involved in chromosome condensation	K06199 crcB; fluoride exporter
D      Natgr_1404 CBS domain-containing protein	K03699 tlyC; magnesium and cobalt exporter, CNNM family
D      Natgr_0433 putative divalent heavy-metal cations transporter	K07238 TC.ZIP; zinc transporter, ZIP family
D      Natgr_0091 putative divalent heavy-metal cations transporter	K07238 TC.ZIP; zinc transporter, ZIP family
D      Natgr_0181 putative divalent heavy-metal cations transporter	K07238 TC.ZIP; zinc transporter, ZIP family
D      Natgr_1430 putative membrane protein	K03298 TC.DME; drug/metabolite transporter, DME family
D      Natgr_3545 L-lactate permease	K03303 lutP; lactate permease
D      Natgr_0952 K+dependent Na+ exchanger related-protein	K07301 yrbG; cation:H+ antiporter
D      Natgr_0526 putative sodium:solute symporter, VC_2705 subfamily	K14393 actP; cation/acetate symporter
D      Natgr_1727 Na+ antiporter NhaC	K24446 arcD; arginine/ornithine antiporter
D      Natgr_0692 Na+ antiporter NhaC	K24446 arcD; arginine/ornithine antiporter
D      Natgr_2302 Na+ antiporter NhaC	K24446 arcD; arginine/ornithine antiporter
D      Natgr_2490 Kef-type K+ transport system, membrane component	K26735 KEA4_5_6; K+:H+ antiporter
D      Natgr_2954 Kef-type K+ transport system, membrane component	K26735 KEA4_5_6; K+:H+ antiporter
D      Natgr_2956 Kef-type K+ transport system, predicted NAD-binding component	K26735 KEA4_5_6; K+:H+ antiporter
D      Natgr_3191 Kef-type K+ transport system, membrane component	K26730 napA; Na+:H+ antiporter
D      Natgr_0197 Trk-type K+ transport system, membrane component	K03498 trkH; trk/ktr system potassium uptake protein
D      Natgr_0191 Trk-type K+ transport system, membrane component	K03498 trkH; trk/ktr system potassium uptake protein
D      Natgr_0196 K+ transport system, NAD-binding component	K03499 trkA; trk/ktr system potassium uptake protein
D      Natgr_2681 K+ transport system, NAD-binding component	K03499 trkA; trk/ktr system potassium uptake protein
D      Natgr_2456 K+ transport system, NAD-binding component	K03499 trkA; trk/ktr system potassium uptake protein
D      Natgr_2457 permease	K06901 pbuG; adenine/guanine/hypoxanthine permease
D      Natgr_1109 Mn2+/Fe2-transporter, NRAMP family	K03322 mntH; manganese transport protein
D      Natgr_2289 Mn2+/Fe2-transporter, NRAMP family	K03322 mntH; manganese transport protein
D      Natgr_2780 Mn2+/Fe2-transporter, NRAMP family	K03322 mntH; manganese transport protein
D      Natgr_2038 arsenite-activated ATPase ArsA	K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-]
D      Natgr_0819 arsenite-activated ATPase ArsA	K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-]
D      Natgr_1722 arsenite-activated ATPase ArsA	K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-]
D      Natgr_3580 arsenite-activated ATPase ArsA	K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-]
D      Natgr_2111 arsenical-resistance protein	K03325 ACR3; arsenite transporter
D      Natgr_3062 multisubunit Na+/H+ antiporter, MnhB subunit	K05566 mnhB; multicomponent Na+:H+ antiporter subunit B
D      Natgr_3063 putative subunit of the multisubunit Na+/H+ antiporter	K05566 mnhB; multicomponent Na+:H+ antiporter subunit B
D      Natgr_3061 multisubunit Na+/H+ antiporter, MnhC subunit	K05567 mnhC; multicomponent Na+:H+ antiporter subunit C
D      Natgr_3058 formate hydrogenlyase subunit 3/multisubunit Na+/H+ antiporter, MnhD subunit	K05568 mnhD; multicomponent Na+:H+ antiporter subunit D
D      Natgr_3059 formate hydrogenlyase subunit 3/multisubunit Na+/H+ antiporter, MnhD subunit	K05568 mnhD; multicomponent Na+:H+ antiporter subunit D
D      Natgr_3060 formate hydrogenlyase subunit 3/multisubunit Na+/H+ antiporter, MnhD subunit	K05568 mnhD; multicomponent Na+:H+ antiporter subunit D
D      Natgr_3066 multisubunit Na+/H+ antiporter, MnhE subunit	K05569 mnhE; multicomponent Na+:H+ antiporter subunit E
D      Natgr_3065 multisubunit Na+/H+ antiporter, MnhF subunit	K05570 mnhF; multicomponent Na+:H+ antiporter subunit F
D      Natgr_3064 monovalent cation/proton antiporter, MnhG/PhaG subunit	K05571 mnhG; multicomponent Na+:H+ antiporter subunit G
D      Natgr_1064 putative branched-chain amino acid permease (azaleucine resistance)	K26605 azlC; branched chain amino acid efflux pump
D      Natgr_1065 putative membrane protein	K26606 azlD; branched chain amino acid efflux pump
D      Natgr_1323 conserved hypothetical integral membrane protein	K09125 yhhQ; queuosine precursor transporter
D      Natgr_1485 ABC-type uncharacterized transport system, permease component	K08970 rcnA; nickel/cobalt transporter (NicO) family protein
D      Natgr_3342 cytochrome c biogenesis protein	K06196 ccdA; cytochrome c-type biogenesis protein
D      Natgr_2518 anaerobic dehydrogenase, typically selenocysteine-containing	K07306 dmsA; anaerobic dimethyl sulfoxide reductase subunit A [EC:1.8.5.3]
D      Natgr_2519 Fe-S-cluster-containing hydrogenase subunit	K00184 dmsB; dimethyl sulfoxide reductase iron-sulfur subunit
D      Natgr_2520 polysulfide reductase	K00185 dmsC; dimethyl sulfoxide reductase membrane subunit
D      Natgr_0551 anaerobic dehydrogenase, typically selenocysteine-containing	K08352 phsA; thiosulfate reductase / polysulfide reductase chain A [EC:1.8.5.5]
D      Natgr_2276 anaerobic dehydrogenase, typically selenocysteine-containing	K08352 phsA; thiosulfate reductase / polysulfide reductase chain A [EC:1.8.5.5]
D      Natgr_0334 small GTP-binding protein domain protein	K04759 feoB; ferrous iron transport protein B
D      Natgr_3700 tryptophan-rich sensory protein	K05770 TSPO; translocator protein
D      Natgr_3128 cytochrome c biogenesis factor	K02198 ccmF; cytochrome c-type biogenesis protein CcmF
C    02044 Secretion system [BR:nge02044]
D      Natgr_1935 archaeal flagellin-like protein	K07325 flaB; archaeal flagellin FlaB
D      Natgr_1937 archaeal flagellin-like protein	K07325 flaB; archaeal flagellin FlaB
D      Natgr_1938 archaeal flagellin-like protein	K07325 flaB; archaeal flagellin FlaB
D      Natgr_1939 archaeal flagellin-like protein	K07325 flaB; archaeal flagellin FlaB
D      Natgr_1934 archaeal flagellin-like protein	K07325 flaB; archaeal flagellin FlaB
D      Natgr_1936 archaeal flagellin-like protein	K07325 flaB; archaeal flagellin FlaB
D      Natgr_1942 archaeal flagella protein/flagella accessory protein C (FlaC)	K23986 flaCE; archaeal flagellar protein FlaCE
D      Natgr_1947 archaeal flagella protein/flagella accessory protein C (FlaC)	K23986 flaCE; archaeal flagellar protein FlaCE
D      Natgr_1940 putative archaeal flagellar protein F	K07329 flaF; archaeal flagellar protein FlaF
D      Natgr_1941 putative archaeal flagellar protein G	K07330 flaG; archaeal flagellar protein FlaG
D      Natgr_1949 putative ATPase involved in flagella biogenesis	K07331 flaH; archaeal flagellar protein FlaH
D      Natgr_1950 ATPase, type IV secretory pathway VirB11 component like protein	K07332 flaI; archaeal flagellar protein FlaI
D      Natgr_0503 ATPase, type IV secretory pathway VirB11 component like protein	K07332 flaI; archaeal flagellar protein FlaI
D      Natgr_1331 ATPase, type IV secretory pathway VirB11 component like protein	K07332 flaI; archaeal flagellar protein FlaI
D      Natgr_0504 archaeal flagella assembly protein J	K07333 flaJ; archaeal flagellar protein FlaJ
D      Natgr_1944 archaeal flagella assembly protein J	K07333 flaJ; archaeal flagellar protein FlaJ
D      Natgr_1743 leader peptidase family protein	K07991 flaK; archaeal preflagellin peptidase FlaK [EC:3.4.23.52]
D      Natgr_3292 putative hydrolase (metallo-beta-lactamase superfamily)	K02238 comEC; competence protein ComEC
D      Natgr_1019 preprotein translocase subunit SecD	K03072 secD; preprotein translocase subunit SecD
D      Natgr_1018 preprotein translocase subunit SecF	K03074 secF; preprotein translocase subunit SecF
D      Natgr_0292 preprotein translocase, SecY subunit	K03076 secY; preprotein translocase subunit SecY
D      Natgr_1557 signal recognition particle GTPase	K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
D      Natgr_1543 signal recognition particle-docking protein FtsY	K03110 ftsY; fused signal recognition particle receptor
D      Natgr_2218 protein translocase SEC61 complex gamma subunit, archaeal and eukaryotic	K07342 SEC61G; protein transport protein SEC61 subunit gamma and related proteins
D      Natgr_3822 signal recognition particle 19 kDa protein	K03105 SRP19; signal recognition particle subunit SRP19
D      Natgr_0500 twin arginine-targeting protein translocase, TatA/E family	K03116 tatA; sec-independent protein translocase protein TatA
D      Natgr_1488 Sec-independent protein secretion pathway component TatC	K03118 tatC; sec-independent protein translocase protein TatC
D      Natgr_1489 Sec-independent protein secretion pathway component TatC	K03118 tatC; sec-independent protein translocase protein TatC
C    02042 Bacterial toxins [BR:nge02042]
D      Natgr_1404 CBS domain-containing protein	K03699 tlyC; magnesium and cobalt exporter, CNNM family
C    02022 Two-component system [BR:nge02022]
D      Natgr_0515 chemotaxis protein histidine kinase-like protein	K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
D      Natgr_1954 chemotaxis protein histidine kinase-like protein	K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
D      Natgr_0517 response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain	K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
D      Natgr_1953 response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
D      Natgr_0516 chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain	K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
D      Natgr_1955 chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain	K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
C    02035 Bacterial motility proteins [BR:nge02035]
D      Natgr_0515 chemotaxis protein histidine kinase-like protein	K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
D      Natgr_1954 chemotaxis protein histidine kinase-like protein	K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
D      Natgr_0518 chemotaxis signal transduction protein	K03408 cheW; purine-binding chemotaxis protein CheW
D      Natgr_1959 chemotaxis signal transduction protein	K03408 cheW; purine-binding chemotaxis protein CheW
D      Natgr_0513 chemotaxis protein CheC, inhibitor of MCP methylation	K03410 cheC; chemotaxis protein CheC
D      Natgr_0514 chemotaxis protein CheC, inhibitor of MCP methylation	K03410 cheC; chemotaxis protein CheC
D      Natgr_1473 chemotaxis protein CheC, inhibitor of MCP methylation	K03410 cheC; chemotaxis protein CheC
D      Natgr_1952 chemotaxis protein CheC, inhibitor of MCP methylation	K03410 cheC; chemotaxis protein CheC
D      Natgr_0512 chemotaxis protein	K03411 cheD; chemotaxis protein CheD [EC:3.5.1.44]
D      Natgr_1472 chemotaxis protein	K03411 cheD; chemotaxis protein CheD [EC:3.5.1.44]
D      Natgr_0511 methylase of chemotaxis methyl-accepting protein	K00575 cheR; chemotaxis protein methyltransferase CheR [EC:2.1.1.80]
D      Natgr_0516 chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain	K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
D      Natgr_1955 chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain	K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
D      Natgr_0517 response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain	K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
D      Natgr_1953 response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
D      Natgr_0256 PAS domain S-box	K03406 mcp; methyl-accepting chemotaxis protein
D      Natgr_0873 methyl-accepting chemotaxis protein	K03406 mcp; methyl-accepting chemotaxis protein
D      Natgr_1099 methyl-accepting chemotaxis protein	K03406 mcp; methyl-accepting chemotaxis protein
D      Natgr_0338 methyl-accepting chemotaxis protein	K03406 mcp; methyl-accepting chemotaxis protein
D      Natgr_1205 methyl-accepting chemotaxis protein	K03406 mcp; methyl-accepting chemotaxis protein
D      Natgr_1208 methyl-accepting chemotaxis protein	K03406 mcp; methyl-accepting chemotaxis protein
D      Natgr_2126 methyl-accepting chemotaxis protein	K03406 mcp; methyl-accepting chemotaxis protein
D      Natgr_1990 methyl-accepting chemotaxis protein	K03406 mcp; methyl-accepting chemotaxis protein
D      Natgr_1906 methyl-accepting chemotaxis protein	K03406 mcp; methyl-accepting chemotaxis protein
D      Natgr_1801 methyl-accepting chemotaxis protein	K03406 mcp; methyl-accepting chemotaxis protein
D      Natgr_1804 methyl-accepting chemotaxis protein	K03406 mcp; methyl-accepting chemotaxis protein
D      Natgr_1654 methyl-accepting chemotaxis protein	K03406 mcp; methyl-accepting chemotaxis protein
D      Natgr_2826 methyl-accepting chemotaxis protein	K03406 mcp; methyl-accepting chemotaxis protein
D      Natgr_3116 methyl-accepting chemotaxis protein	K03406 mcp; methyl-accepting chemotaxis protein
D      Natgr_3162 methyl-accepting chemotaxis protein	K03406 mcp; methyl-accepting chemotaxis protein
D      Natgr_3559 methyl-accepting chemotaxis protein	K03406 mcp; methyl-accepting chemotaxis protein
D      Natgr_3799 PAS domain S-box	K03406 mcp; methyl-accepting chemotaxis protein
D      Natgr_3205 methyl-accepting chemotaxis protein	K06595 hemAT; heam-based aerotactic trancducer
D      Natgr_1161 methyl-accepting chemotaxis protein	K06595 hemAT; heam-based aerotactic trancducer
D      Natgr_2322 methyl-accepting chemotaxis protein	K06595 hemAT; heam-based aerotactic trancducer
D      Natgr_1935 archaeal flagellin-like protein	K07325 flaB; archaeal flagellin FlaB
D      Natgr_1937 archaeal flagellin-like protein	K07325 flaB; archaeal flagellin FlaB
D      Natgr_1938 archaeal flagellin-like protein	K07325 flaB; archaeal flagellin FlaB
D      Natgr_1939 archaeal flagellin-like protein	K07325 flaB; archaeal flagellin FlaB
D      Natgr_1934 archaeal flagellin-like protein	K07325 flaB; archaeal flagellin FlaB
D      Natgr_1936 archaeal flagellin-like protein	K07325 flaB; archaeal flagellin FlaB
D      Natgr_1942 archaeal flagella protein/flagella accessory protein C (FlaC)	K23986 flaCE; archaeal flagellar protein FlaCE
D      Natgr_1947 archaeal flagella protein/flagella accessory protein C (FlaC)	K23986 flaCE; archaeal flagellar protein FlaCE
D      Natgr_1940 putative archaeal flagellar protein F	K07329 flaF; archaeal flagellar protein FlaF
D      Natgr_1941 putative archaeal flagellar protein G	K07330 flaG; archaeal flagellar protein FlaG
D      Natgr_1949 putative ATPase involved in flagella biogenesis	K07331 flaH; archaeal flagellar protein FlaH
D      Natgr_1950 ATPase, type IV secretory pathway VirB11 component like protein	K07332 flaI; archaeal flagellar protein FlaI
D      Natgr_0503 ATPase, type IV secretory pathway VirB11 component like protein	K07332 flaI; archaeal flagellar protein FlaI
D      Natgr_1331 ATPase, type IV secretory pathway VirB11 component like protein	K07332 flaI; archaeal flagellar protein FlaI
D      Natgr_0504 archaeal flagella assembly protein J	K07333 flaJ; archaeal flagellar protein FlaJ
D      Natgr_1944 archaeal flagella assembly protein J	K07333 flaJ; archaeal flagellar protein FlaJ
D      Natgr_1743 leader peptidase family protein	K07991 flaK; archaeal preflagellin peptidase FlaK [EC:3.4.23.52]
C    03037 Cilium and associated proteins
C    04812 Cytoskeleton proteins [BR:nge04812]
D      Natgr_0956 cell division protein FtsZ	K03531 ftsZ; cell division protein FtsZ
D      Natgr_2506 cell division protein FtsZ	K03531 ftsZ; cell division protein FtsZ
D      Natgr_1361 cell division GTPase	K22222 cetZ; tubulin-like protein CetZ
D      Natgr_1127 cell division GTPase	K22222 cetZ; tubulin-like protein CetZ
D      Natgr_0008 cell division GTPase	K22222 cetZ; tubulin-like protein CetZ
D      Natgr_2351 cell division GTPase	K22222 cetZ; tubulin-like protein CetZ
D      Natgr_0663 cell division GTPase	K22222 cetZ; tubulin-like protein CetZ
D      Natgr_2350 cell division GTPase	K22222 cetZ; tubulin-like protein CetZ
D      Natgr_1339 ATPase involved in chromosome partitioning	K03609 minD; septum site-determining protein MinD
D      Natgr_2003 cell division ATPase MinD, archaeal	K03609 minD; septum site-determining protein MinD
D      Natgr_1957 ATPase involved in chromosome partitioning	K03496 parA; chromosome partitioning protein
D      Natgr_2769 ATPase involved in chromosome partitioning	K03496 parA; chromosome partitioning protein
C    04147 Exosome [BR:nge04147]
D      Natgr_2561 phosphopyruvate hydratase	K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D      Natgr_2895 glyceraldehyde-3-phosphate dehydrogenase, type I	K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D      Natgr_1663 glyceraldehyde-3-phosphate dehydrogenase, type I	K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D      Natgr_1662 3-phosphoglycerate kinase	K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]
D      Natgr_0653 pyruvate kinase	K00873 PK; pyruvate kinase [EC:2.7.1.40]
D      Natgr_1173 peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	K03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8]
D      Natgr_1174 peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	K03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8]
D      Natgr_3156 peroxiredoxin	K03386 PRDX2_4; peroxiredoxin 2/4 [EC:1.11.1.24]
D      Natgr_0889 translation elongation factor EF-1 alpha	K03231 EEF1A; elongation factor 1-alpha
D      Natgr_2849 GTPase	K03231 EEF1A; elongation factor 1-alpha
D      Natgr_1210 translation elongation factor aEF-2	K03234 EEF2; elongation factor 2
D      Natgr_3218 chaperone protein DnaK	K04043 dnaK; molecular chaperone DnaK
D      Natgr_1014 glucose-6-phosphate isomerase	K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]
D      Natgr_0722 flap structure-specific endonuclease	K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D      Natgr_2810 IMP dehydrogenase/GMP reductase	K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]
D      Natgr_3267 inosine-5''-monophosphate dehydrogenase	K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]
D      Natgr_2109 ribosomal protein S27AE	K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae
D      Natgr_3747 AAA family ATPase, CDC48 subfamily	K13525 VCP; transitional endoplasmic reticulum ATPase
D      Natgr_3711 AAA family ATPase, CDC48 subfamily	K13525 VCP; transitional endoplasmic reticulum ATPase
D      Natgr_1680 HIT family hydrolase, diadenosine tetraphosphate hydrolase	K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
D      Natgr_2883 HIT family hydrolase, diadenosine tetraphosphate hydrolase	K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
D      Natgr_1229 AMP-forming long-chain acyl-CoA synthetase	K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D      Natgr_1230 AMP-forming long-chain acyl-CoA synthetase	K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D      Natgr_0823 acetyl-CoA acetyltransferase	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      Natgr_0426 acetyl-CoA acetyltransferase	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      Natgr_1255 acetyl-CoA acetyltransferase	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      Natgr_3067 acetyl-CoA acetyltransferase	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      Natgr_3496 acetyl-CoA acetyltransferase	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      Natgr_1780 adenosylhomocysteinase	K01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1]
D      Natgr_0140 adenylate kinase family protein	K00939 adk; adenylate kinase [EC:2.7.4.3]
D      Natgr_0812 PRPP-binding protein, adenine/guanine phosphoribosyltransferase	K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7]
D      Natgr_2478 PRPP-binding protein, adenine/guanine phosphoribosyltransferase	K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7]
D      Natgr_1610 argininosuccinate lyase	K01755 argH; argininosuccinate lyase [EC:4.3.2.1]
D      Natgr_1609 argininosuccinate synthase	K01940 argG; argininosuccinate synthase [EC:6.3.4.5]
D      Natgr_3575 cystathionine beta-lyase/cystathionine gamma-synthase	K01758 CTH; cystathionine gamma-lyase [EC:4.4.1.1]
D      Natgr_2150 cystathionine beta-lyase/cystathionine gamma-synthase	K01758 CTH; cystathionine gamma-lyase [EC:4.4.1.1]
D      Natgr_2901 fructose-1,6-bisphosphatase	K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]
D      Natgr_2338 glutamine synthetase	K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D      Natgr_3111 glutamine synthetase, type I	K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D      Natgr_1463 delta-aminolevulinic acid dehydratase	K01698 hemB; porphobilinogen synthase [EC:4.2.1.24]
D      Natgr_3195 pterin-4a-carbinolamine dehydratase	K01724 PCBD; 4a-hydroxytetrahydrobiopterin dehydratase [EC:4.2.1.96]
D      Natgr_1696 D-3-phosphoglycerate dehydrogenase	K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
D      Natgr_3368 lactate dehydrogenase-like oxidoreductase	K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
D      Natgr_1350 dihydrolipoamide dehydrogenase	K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D      Natgr_1993 electron transfer flavoprotein, alpha subunit	K03522 fixB; electron transfer flavoprotein alpha subunit
D      Natgr_2923 electron transfer flavoprotein, alpha subunit	K03522 fixB; electron transfer flavoprotein alpha subunit
D      Natgr_0343 electron transfer flavoprotein, alpha subunit	K03522 fixB; electron transfer flavoprotein alpha subunit
D      Natgr_0577 glutamate dehydrogenase/leucine dehydrogenase	K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]
D      Natgr_2884 glutamate dehydrogenase/leucine dehydrogenase	K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]
D      Natgr_3595 triosephosphate isomerase	K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
C    02048 Prokaryotic defense system [BR:nge02048]
D      Natgr_3461 CRISPR-associated endonuclease Cas1	K15342 cas1; CRISP-associated protein Cas1
D      Natgr_3462 CRISPR-associated endoribonuclease Cas2	K09951 cas2; CRISPR-associated protein Cas2
D      Natgr_3459 CRISPR-associated endonuclease Cas3-HD	K07475 cas3; CRISPR-associated endonuclease Cas3-HD [EC:3.1.-.-]
D      Natgr_3460 CRISPR-associated protein Cas4	K07464 cas4; CRISPR-associated exonuclease Cas4 [EC:3.1.12.1]
D      Natgr_3455 CRISPR-associated endoribonuclease Cas6	K19091 cas6; CRISPR-associated endoribonuclease Cas6 [EC:3.1.-.-]
D      Natgr_3457 CRISPR-associated protein Cas7/Csh2, subtype I-B/HMARI	K19115 csh2; CRISPR-associated protein Csh2
D      Natgr_3458 CRISPR-associated protein Cas5, subtype I-B/HMARI	K19116 cas5h; CRISPR-associated protein Cas5h
D      Natgr_3510 type I restriction-modification system methyltransferase subunit	K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72]
D      Natgr_0150 site-specific DNA methylase	K06223 dam; DNA adenine methylase [EC:2.1.1.72]
D      Natgr_1531 DNA modification methylase	K00571 E2.1.1.72; site-specific DNA-methyltransferase (adenine-specific) [EC:2.1.1.72]
D      Natgr_0166 DNA-methyltransferase Dcm	K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D      Natgr_2595 DNA-methyltransferase Dcm	K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D      Natgr_3776 DNA modification methylase	K24451 zim; modification methylase
D      Natgr_2624 Restriction endonuclease	K07448 mrr; restriction system protein
D      Natgr_0224 growth inhibitor	K07171 mazF; mRNA interferase MazF [EC:3.1.-.-]
D      Natgr_1625 looped-hinge helix DNA binding domain, AbrB family	K19156 prlF; antitoxin PrlF
D      Natgr_0263 cytotoxic translational repressor of toxin-antitoxin stability system	K06218 relE; mRNA interferase RelE/StbE
D      Natgr_0956 cell division protein FtsZ	K03531 ftsZ; cell division protein FtsZ
D      Natgr_2506 cell division protein FtsZ	K03531 ftsZ; cell division protein FtsZ
D      Natgr_2571 glutamyl-tRNA synthetase, archaeal and eukaryotic family	K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D      Natgr_1012 putative nucleic acid-binding protein with PIN domain and Zn ribbon	K07060 nob1; endoribonuclease Nob1 [EC:3.1.-.-]
C    04030 G protein-coupled receptors [BR:nge04030]
D      Natgr_3014 bacteriorhodopsin	K04642 hop; halorhodopsin
D      Natgr_1803 bacteriorhodopsin	K04643 sop; sensory rhodopsin
D      Natgr_2495 hypothetical protein	K04643 sop; sensory rhodopsin
D      Natgr_0872 bacteriorhodopsin	K04643 sop; sensory rhodopsin
D      Natgr_3585 Bacteriorhodopsin-like protein	K04643 sop; sensory rhodopsin
D      Natgr_2494 bacteriorhodopsin	K04643 sop; sensory rhodopsin
C    04050 Cytokine receptors
C    04054 Pattern recognition receptors
C    03310 Nuclear receptors
C    04040 Ion channels
C    04031 GTP-binding proteins
C    04052 Cytokines and neuropeptides
C    04515 Cell adhesion molecules
C    04090 CD molecules [BR:nge04090]
C    01504 Antimicrobial resistance genes [BR:nge01504]
D      Natgr_1372 acetyltransferase (isoleucine patch superfamily)	K18234 vat; virginiamycin A acetyltransferase [EC:2.3.1.-]
C    00535 Proteoglycans
C    00536 Glycosaminoglycan binding proteins
C    00537 Glycosylphosphatidylinositol (GPI)-anchored proteins
C    04091 Lectins
C    04990 Domain-containing proteins not elsewhere classified
B
B  09185 Viral protein families
C    03200 Viral proteins
C    03210 Viral fusion proteins
B
B  09184 RNA family
C    03100 Non-coding RNAs [BR:nge03100]
D      Natgr_1345 tRNA-Ala	K14218 tRNA-Ala; tRNA Ala
D      Natgr_3795 tRNA-Ala	K14218 tRNA-Ala; tRNA Ala
D      Natgr_1834 tRNA-Ala	K14218 tRNA-Ala; tRNA Ala
D      Natgr_0944 tRNA-Ala	K14218 tRNA-Ala; tRNA Ala
D      Natgr_0892 tRNA-Ala	K14218 tRNA-Ala; tRNA Ala
D      Natgr_0624 tRNA-Arg	K14219 tRNA-Arg; tRNA Arg
D      Natgr_0501 tRNA-Arg	K14219 tRNA-Arg; tRNA Arg
D      Natgr_1550 tRNA-Arg	K14219 tRNA-Arg; tRNA Arg
D      Natgr_1288 tRNA-Arg	K14219 tRNA-Arg; tRNA Arg
D      Natgr_1293 tRNA-Asn	K14220 tRNA-Asn; tRNA Asn
D      Natgr_1653 tRNA-Asp	K14221 tRNA-Asp; tRNA Asp
D      Natgr_1655 tRNA-Asp	K14221 tRNA-Asp; tRNA Asp
D      Natgr_1837 tRNA-Cys	K14222 tRNA-Cys; tRNA Cys
D      Natgr_0879 tRNA-Gln	K14223 tRNA-Gln; tRNA Gln
D      Natgr_1518 tRNA-Gln	K14223 tRNA-Gln; tRNA Gln
D      Natgr_2589 tRNA-Glu	K14224 tRNA-Glu; tRNA Glu
D      Natgr_3694 tRNA-Glu	K14224 tRNA-Glu; tRNA Glu
D      Natgr_1652 tRNA-Gly	K14225 tRNA-Gly; tRNA Gly
D      Natgr_3601 tRNA-Gly	K14225 tRNA-Gly; tRNA Gly
D      Natgr_0727 tRNA-Gly	K14225 tRNA-Gly; tRNA Gly
D      Natgr_1305 tRNA-His	K14226 tRNA-His; tRNA His
D      Natgr_1165 tRNA-Ile	K14227 tRNA-Ile; tRNA Ile
D      Natgr_0360 tRNA-Leu	K14228 tRNA-Leu; tRNA Leu
D      Natgr_2555 tRNA-Leu	K14228 tRNA-Leu; tRNA Leu
D      Natgr_0204 tRNA-Leu	K14228 tRNA-Leu; tRNA Leu
D      Natgr_2176 tRNA-Leu	K14228 tRNA-Leu; tRNA Leu
D      Natgr_1177 tRNA-Leu	K14228 tRNA-Leu; tRNA Leu
D      Natgr_1899 tRNA-Lys	K14229 tRNA-Lys; tRNA Lys
D      Natgr_3234 tRNA-Lys	K14229 tRNA-Lys; tRNA Lys
D      Natgr_1830 tRNA-Met	K14230 tRNA-Met; tRNA Met
D      Natgr_3772 tRNA-Met	K14230 tRNA-Met; tRNA Met
D      Natgr_0796 tRNA-Met	K14230 tRNA-Met; tRNA Met
D      Natgr_1309 tRNA-Phe	K14231 tRNA-Phe; tRNA Phe
D      Natgr_1029 tRNA-Pro	K14232 tRNA-Pro; tRNA Pro
D      Natgr_0147 tRNA-Pro	K14232 tRNA-Pro; tRNA Pro
D      Natgr_1741 tRNA-Pro	K14232 tRNA-Pro; tRNA Pro
D      Natgr_2550 tRNA-Ser	K14233 tRNA-Ser; tRNA Ser
D      Natgr_2331 tRNA-Ser	K14233 tRNA-Ser; tRNA Ser
D      Natgr_3382 tRNA-Ser	K14233 tRNA-Ser; tRNA Ser
D      Natgr_0715 tRNA-Ser	K14233 tRNA-Ser; tRNA Ser
D      Natgr_1646 tRNA-Thr	K14234 tRNA-Thr; tRNA Thr
D      Natgr_0099 tRNA-Thr	K14234 tRNA-Thr; tRNA Thr
D      Natgr_3269 tRNA-Trp	K14235 tRNA-Trp; tRNA Trp
D      Natgr_2509 tRNA-Tyr	K14236 tRNA-Tyr; tRNA Tyr
D      Natgr_3759 tRNA-Val	K14237 tRNA-Val; tRNA Val
D      Natgr_1311 tRNA-Val	K14237 tRNA-Val; tRNA Val
D      Natgr_2999 tRNA-Val	K14237 tRNA-Val; tRNA Val
D      Natgr_1833 16S ribosomal RNA	K01977 16SrRNA; 16S ribosomal RNA
D      Natgr_1346 16S ribosomal RNA	K01977 16SrRNA; 16S ribosomal RNA
D      Natgr_3796 16S ribosomal RNA	K01977 16SrRNA; 16S ribosomal RNA
D      Natgr_3794 23S ribosomal RNA	K01980 23SrRNA; 23S ribosomal RNA
D      Natgr_1835 23S ribosomal RNA	K01980 23SrRNA; 23S ribosomal RNA
D      Natgr_1344 23S ribosomal RNA	K01980 23SrRNA; 23S ribosomal RNA
D      Natgr_1343 5S ribosomal RNA	K01985 5SrRNA; 5S ribosomal RNA
D      Natgr_3793 5S ribosomal RNA	K01985 5SrRNA; 5S ribosomal RNA
D      Natgr_1836 5S ribosomal RNA	K01985 5SrRNA; 5S ribosomal RNA
#
A09190 Not Included in Pathway or Brite
B
B  09191 Unclassified: metabolism
C    99980 Enzymes with EC numbers
D      Natgr_0321 aldo/keto reductase, diketogulonate reductase	K06222 dkgB; 2,5-diketo-D-gluconate reductase B [EC:1.1.1.346]
D      Natgr_3615 aldo/keto reductase, diketogulonate reductase	K06222 dkgB; 2,5-diketo-D-gluconate reductase B [EC:1.1.1.346]
D      Natgr_3243 pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase component alpha subunit	K21416 acoA; acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit alpha [EC:1.1.1.-]
D      Natgr_3242 pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase component beta subunit	K21417 acoB; acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit beta [EC:1.1.1.-]
D      Natgr_3262 putative non-F420 flavinoid oxidoreductase	K15510 fgd1; coenzyme F420-dependent glucose-6-phosphate dehydrogenase [EC:1.1.98.2]
D      Natgr_0672 putative oxidoreductase, aryl-alcohol dehydrogenase like protein	K23107 yajO; 1-deoxyxylulose-5-phosphate synthase [EC:1.1.-.-]
D      Natgr_2812 putative oxidoreductase, aryl-alcohol dehydrogenase like protein	K23107 yajO; 1-deoxyxylulose-5-phosphate synthase [EC:1.1.-.-]
D      Natgr_2708 hypothetical protein	K25950 amdH; secondary-alkyl amine dehydrogenase [NAD(P)+] [EC:1.4.1.28]
D      Natgr_2018 NADPH-dependent F420 reductase	K06988 fno; 8-hydroxy-5-deazaflavin:NADPH oxidoreductase [EC:1.5.1.40]
D      Natgr_3791 flavin-dependent dehydrogenase	K00311 ETFDH; electron-transferring-flavoprotein dehydrogenase [EC:1.5.5.1]
D      Natgr_0344 flavin-dependent dehydrogenase	K00313 fixC; electron transfer flavoprotein-quinone oxidoreductase [EC:1.5.5.-]
D      Natgr_3324 putative NAD/FAD-dependent oxidoreductase	K18208 RNLS; renalase [EC:1.6.3.5]
D      Natgr_3662 putative NAD(P)H quinone oxidoreductase, PIG3 family	K00344 qor; NADPH:quinone reductase [EC:1.6.5.5]
D      Natgr_1559 pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase component	K17883 mtr; mycothione reductase [EC:1.8.1.15]
D      Natgr_2808 methionine-S-sulfoxide reductase	K07304 msrA; peptide-methionine (S)-S-oxide reductase [EC:1.8.4.11]
D      Natgr_2211 methionine-R-sulfoxide reductase	K07305 msrB; peptide-methionine (R)-S-oxide reductase [EC:1.8.4.12]
D      Natgr_2454 putative glutathione S-transferase	K07393 ECM4; glutathionyl-hydroquinone reductase [EC:1.8.5.7]
D      Natgr_3126 cytochrome c peroxidase	K00428 E1.11.1.5; cytochrome c peroxidase [EC:1.11.1.5]
D      Natgr_0540 putative hydrolase or acyltransferase of alpha/beta superfamily	K00433 cpo; non-heme chloroperoxidase [EC:1.11.1.10]
D      Natgr_1391 Peroxiredoxin	K03564 BCP; thioredoxin-dependent peroxiredoxin [EC:1.11.1.24]
D      Natgr_0499 Peroxiredoxin	K24129 K24129; glutaredoxin-dependent peroxiredoxin [EC:1.11.1.25]
D      Natgr_1402 Peroxiredoxin	K24129 K24129; glutaredoxin-dependent peroxiredoxin [EC:1.11.1.25]
D      Natgr_0246 beta-carotene 15,15''-monooxygenase, Brp/Blh family	K21817 blh; beta-carotene 15,15'-dioxygenase [EC:1.13.11.63]
D      Natgr_2794 protein-tyrosine-phosphatase	K03741 arsC; arsenate reductase (thioredoxin) [EC:1.20.4.4]
D      Natgr_0645 putative Fe-S oxidoreductase	K06937 E1.21.98.5; tetraether lipid synthase [EC:1.21.98.5]
D      Natgr_1658 protein-L-isoaspartate carboxylmethyltransferase	K00573 E2.1.1.77; protein-L-isoaspartate(D-aspartate) O-methyltransferase [EC:2.1.1.77]
D      Natgr_1659 protein-L-isoaspartate and D-aspartate O-methyltransferase	K00573 E2.1.1.77; protein-L-isoaspartate(D-aspartate) O-methyltransferase [EC:2.1.1.77]
D      Natgr_0089 diphthine synthase	K20215 dph5; diphthine synthase [EC:2.1.1.98]
D      Natgr_1909 acetyltransferase	K22441 paiA; diamine N-acetyltransferase [EC:2.3.1.57]
D      Natgr_3253 glycosyltransferase	K15521 mshA; D-inositol-3-phosphate glycosyltransferase [EC:2.4.1.250]
D      Natgr_0279 deoxyhypusine synthase	K00809 DHPS; deoxyhypusine synthase [EC:2.5.1.46]
D      Natgr_1052 queuine tRNA-ribosyltransferase	K07557 tgtA2; archaeosine synthase alpha-subunit [EC:2.6.1.97 2.6.1.-]
D      Natgr_1078 TIGR01210 family protein	K06936 raSEA; archaeosine synthase beta-subunit [EC:2.6.1.-]
D      Natgr_0361 hypothetical protein	K18672 dacA; diadenylate cyclase [EC:2.7.7.85]
D      Natgr_1185 dinucleotide-utilizing enzyme possibly involved in molybdopterin or thiamin biosynthesis	K22837 ubaA; SAMP-activating enzyme [EC:2.7.7.100]
D      Natgr_3598 phosphatidylglycerophosphate synthase	K17884 E2.7.8.39; archaetidylinositol phosphate synthase [EC:2.7.8.39]
D      Natgr_3221 putative phosphatase, C-terminal domain of histone macro H2A1 like protein	K23518 MACROD; O-acetyl-ADP-ribose deacetylase [EC:3.1.1.106]
D      Natgr_0931 acyl-CoA thioester hydrolase, YbgC/YbaW family	K07107 ybgC; acyl-CoA thioester hydrolase [EC:3.1.2.-]
D      Natgr_3491 putative thioesterase	K07107 ybgC; acyl-CoA thioester hydrolase [EC:3.1.2.-]
D      Natgr_1030 putative nuclease of the RecB family	K07503 nucS; endonuclease [EC:3.1.-.-]
D      Natgr_2524 putative nuclease of the RecB family	K07503 nucS; endonuclease [EC:3.1.-.-]
D      Natgr_2945 nucleoside 2-deoxyribosyltransferase	K22928 DNPH1; 2'-deoxynucleoside 5'-phosphate N-hydrolase [EC:3.2.2.-]
D      Natgr_0716 MoxR-like ATPase	K03924 moxR; MoxR-like ATPase [EC:3.6.3.-]
D      Natgr_1356 MoxR-like ATPase	K03924 moxR; MoxR-like ATPase [EC:3.6.3.-]
D      Natgr_2053 MoxR-like ATPase	K03924 moxR; MoxR-like ATPase [EC:3.6.3.-]
D      Natgr_0770 hypothetical protein	K22205 E3.13.2.3; S-adenosyl-L-methionine hydrolase (adenosine-forming) [EC:3.13.2.3]
D      Natgr_3571 yjeF-like protein, hydroxyethylthiazole kinase-related protein	K17758 nnrD; ADP-dependent NAD(P)H-hydrate dehydratase [EC:4.2.1.136]
D      Natgr_0374 yjeF-like protein, hydroxyethylthiazole kinase-related protein	K23997 nnr; ADP-dependent NAD(P)H-hydrate dehydratase / NAD(P)H-hydrate epimerase [EC:4.2.1.136 5.1.99.6]
D      Natgr_3708 putative ATP-grasp enzyme	K17810 asl; D-aspartate ligase [EC:6.3.1.12]
D      Natgr_2725 RNA 3'-phosphate cyclase	K01974 RTCA; RNA 3'-terminal phosphate cyclase (ATP) [EC:6.5.1.4]
D      Natgr_1823 copper/silver-translocating P-type ATPase	K01533 copB; P-type Cu2+ transporter [EC:7.2.2.9]
D      Natgr_2868 heavy metal translocating P-type ATPase	K01533 copB; P-type Cu2+ transporter [EC:7.2.2.9]
D      Natgr_0424 P-type ATPase, translocating	K01537 ATP2C; P-type Ca2+ transporter type 2C [EC:7.2.2.10]
D      Natgr_0475 heavy metal-translocating P-type ATPase, Cd/Co/Hg/Pb/Zn-transporting	K01534 zntA; Zn2+/Cd2+-exporting ATPase [EC:7.2.2.12 7.2.2.21]
D      Natgr_0096 heavy metal-translocating P-type ATPase, Cd/Co/Hg/Pb/Zn-transporting	K01534 zntA; Zn2+/Cd2+-exporting ATPase [EC:7.2.2.12 7.2.2.21]
C    99981 Carbohydrate metabolism
D      Natgr_3020 hypothetical protein	K00782 lldG; L-lactate dehydrogenase complex protein LldG
C    99982 Energy metabolism
D      Natgr_1709 ferredoxin	K05337 fer; ferredoxin
D      Natgr_0109 ferredoxin	K05337 fer; ferredoxin
D      Natgr_1520 SUF system FeS assembly protein, NifU family	K04488 iscU; nitrogen fixation protein NifU and related proteins
D      Natgr_0342 electron transfer flavoprotein, beta subunit	K03521 fixA; electron transfer flavoprotein beta subunit
D      Natgr_1994 electron transfer flavoprotein, beta subunit	K03521 fixA; electron transfer flavoprotein beta subunit
D      Natgr_2922 electron transfer flavoprotein, beta subunit	K03521 fixA; electron transfer flavoprotein beta subunit
D      Natgr_3801 hypothetical protein	K09165 K09165; dodecin
C    99983 Lipid metabolism
C    99984 Nucleotide metabolism
C    99985 Amino acid metabolism
C    99986 Glycan metabolism
D      Natgr_0332 hypothetical protein	K07027 K07027; glycosyltransferase 2 family protein
D      Natgr_2000 hypothetical protein	K07027 K07027; glycosyltransferase 2 family protein
C    99987 Cofactor metabolism
D      Natgr_3235 molybdopterin-guanine dinucleotide biosynthesis protein	K03753 mobB; molybdopterin-guanine dinucleotide biosynthesis adapter protein
C    99988 Secondary metabolism
C    99999 Others
D      Natgr_1562 putative esterase	K06999 K06999; phospholipase/carboxylesterase
B
B  09192 Unclassified: genetic information processing
C    99973 Transcription
D      Natgr_3596 TIGR00270 family protein	K03627 MBF1; putative transcription factor
D      Natgr_0673 cold shock protein	K03704 cspA; cold shock protein
D      Natgr_1675 cold shock protein	K03704 cspA; cold shock protein
D      Natgr_2932 cold shock protein	K03704 cspA; cold shock protein
D      Natgr_2300 cold shock protein	K03704 cspA; cold shock protein
D      Natgr_2077 small nuclear ribonucleoprotein	K04796 RUXX; small nuclear ribonucleoprotein
D      Natgr_0915 putative transcriptional regulator containing an HTH domain fused to a Zn-ribbon	K07743 K07743; transcriptional regulator
D      Natgr_0182 putative transcriptional regulator, contains C-terminal CBS domains	K07744 K07744; transcriptional regulator
C    99974 Translation
D      Natgr_2147 putative RNA-binding protein	K07572 K07572; putative nucleotide binding protein
D      Natgr_1918 putative exonuclease of the beta-lactamase fold involved in RNA processing	K07577 K07577; putative mRNA 3-end processing factor
D      Natgr_0040 putative RNA methylase	K07579 K07579; putative methylase
D      Natgr_2100 putative Zn-ribbon RNA-binding protein with a function in translation	K07580 K07580; Zn-ribbon RNA-binding protein
D      Natgr_2836 putative exosome subunit	K07581 K07581; RNA-binding protein
D      Natgr_2426 putative subunit of tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain	K07585 K07585; tRNA methyltransferase
C    99975 Protein processing
D      Natgr_0423 hypothetical protein	K17247 msrQ; methionine sulfoxide reductase heme-binding subunit
D      Natgr_2163 hydrogenase assembly chaperone HypC/HupF	K04653 hypC; hydrogenase expression/formation protein HypC
D      Natgr_2164 hydrogenase expression/formation protein HypD	K04654 hypD; hydrogenase expression/formation protein HypD
D      Natgr_2165 hydrogenase expression/formation protein HypE	K04655 hypE; hydrogenase expression/formation protein HypE
D      Natgr_2067 hydrogenase maturation factor	K04655 hypE; hydrogenase expression/formation protein HypE
D      Natgr_2382 hydrogenase maturation factor	K04655 hypE; hydrogenase expression/formation protein HypE
D      Natgr_2168 (NiFe) hydrogenase maturation protein HypF	K04656 hypF; hydrogenase maturation protein HypF
D      Natgr_0975 prefoldin alpha subunit	K07398 K07398; conserved protein with predicted RNA binding PUA domain
D      Natgr_0886 thioredoxin-like protein	K07400 nfuA; Fe/S biogenesis protein NfuA
D      Natgr_0230 selT/selW/selH selenoprotein domain protein	K07401 K07401; selenoprotein W-related protein
C    99976 Replication and repair
D      Natgr_2635 hypothetical protein	K07454 K07454; putative restriction endonuclease
D      Natgr_1568 putative endonuclease containing a URI domain	K07461 K07461; putative endonuclease
D      Natgr_1845 phage terminase large subunit	K06909 xtmB; phage terminase large subunit
D      Natgr_2473 transposase	K07486 K07486; transposase
D      Natgr_2328 transposase	K07491 rayT; REP-associated tyrosine transposase
D      Natgr_3096 transposase	K07491 rayT; REP-associated tyrosine transposase
D      Natgr_1381 transposase, IS605 OrfB family, central region	K07496 K07496; putative transposase
D      Natgr_3365 transposase, IS605 OrfB family, central region	K07496 K07496; putative transposase
D      Natgr_1548 transposase, IS605 OrfB family, central region	K07496 K07496; putative transposase
D      Natgr_2224 transposase	K07496 K07496; putative transposase
D      Natgr_3102 transposase, IS605 OrfB family, central region	K07496 K07496; putative transposase
D      Natgr_1634 transposase, IS605 OrfB family, central region	K07496 K07496; putative transposase
D      Natgr_0875 transposase, IS605 OrfB family, central region	K07496 K07496; putative transposase
D      Natgr_3809 transposase	K07496 K07496; putative transposase
D      Natgr_2332 transposase, IS605 OrfB family, central region	K07496 K07496; putative transposase
D      Natgr_1844 Transposase	K07497 K07497; putative transposase
D      Natgr_2486 transposase	K07498 K07498; putative transposase
C    99979 Viral proteins
C    99998 Others
D      Natgr_2697 phage shock protein A (IM30), suppresses sigma54-dependent transcription	K03969 pspA; phage shock protein A
D      Natgr_2653 hypothetical protein	K07504 K07504; predicted type IV restriction endonuclease
B
B  09193 Unclassified: signaling and cellular processes
C    99977 Transport
D      Natgr_3043 formate/nitrite transporter family protein	K21990 yfdC; formate-nitrite transporter family protein
D      Natgr_2397 amino acid transporter	K03294 TC.APA; basic amino acid/polyamine antiporter, APA family
D      Natgr_1080 phosphate/sulfate permease	K03306 TC.PIT; inorganic phosphate transporter, PiT family
D      Natgr_1406 phosphate/sulfate permease	K03306 TC.PIT; inorganic phosphate transporter, PiT family
D      Natgr_1745 phosphate/sulfate permease	K03306 TC.PIT; inorganic phosphate transporter, PiT family
D      Natgr_1750 phosphate/sulfate permease	K03306 TC.PIT; inorganic phosphate transporter, PiT family
D      Natgr_1748 phosphate/sulfate permease	K03306 TC.PIT; inorganic phosphate transporter, PiT family
D      Natgr_1711 phosphate/sulfate permease	K03306 TC.PIT; inorganic phosphate transporter, PiT family
D      Natgr_0876 Na+/proline symporter	K03307 TC.SSS; solute:Na+ symporter, SSS family
D      Natgr_3184 Na+/proline symporter	K03307 TC.SSS; solute:Na+ symporter, SSS family
D      Natgr_0601 SNF family Na+-dependent transporter	K03308 TC.NSS; neurotransmitter:Na+ symporter, NSS family
D      Natgr_3044 SNF family Na+-dependent transporter	K03308 TC.NSS; neurotransmitter:Na+ symporter, NSS family
D      Natgr_1180 putative Na+-dependent transporter	K03453 TC.BASS; bile acid:Na+ symporter, BASS family
C    99978 Cell growth
D      Natgr_2824 hypothetical protein	K06415 spoVR; stage V sporulation protein R
C    99993 Cell motility
D      Natgr_1932 hypothetical protein	K09156 cheF; taxis protein CheF
D      Natgr_1951 hypothetical protein	K09156 cheF; taxis protein CheF
D      Natgr_3774 hypothetical protein	K09156 cheF; taxis protein CheF
D      Natgr_1931 HEAT repeat-containing protein	K22221 K22221; HEAT repeat-containing taxis protein
D      Natgr_0157 archaeal flagellin-like protein	K23255 pilA; archaeal type IV pilus assembly protein PilA
D      Natgr_0636 archaeal flagellin-like protein	K23255 pilA; archaeal type IV pilus assembly protein PilA
D      Natgr_2512 archaeal flagellin-like protein	K23255 pilA; archaeal type IV pilus assembly protein PilA
D      Natgr_1031 Protein of unknown function (DUF1628)	K23255 pilA; archaeal type IV pilus assembly protein PilA
D      Natgr_1984 archaeal flagellin-like protein	K23255 pilA; archaeal type IV pilus assembly protein PilA
D      Natgr_3117 periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)	K23316 cosB; chemotactic signal transduction system substrate-binding protein CosB
C    99995 Signaling proteins
D      Natgr_3579 carbon starvation protein, predicted membrane protein	K06200 cstA; carbon starvation protein
D      Natgr_2821 putative Ser protein kinase	K07180 prkA; serine protein kinase
D      Natgr_2425 DNA-binding protein	K06875 PDCD5; programmed cell death protein 5
C    99992 Structural proteins
D      Natgr_3173 hypothetical protein	K04062 osmB; osmotically inducible lipoprotein OsmB
D      Natgr_3133 cytochrome c-type biogenesis protein CcmE	K02197 ccmE; cytochrome c-type biogenesis protein CcmE
D      Natgr_3079 Gas vesicle protein	K23262 gvpA; gas vesicle structural protein
D      Natgr_0893 PGF-CTERM archaeal protein-sorting signal	K26284 csg; S-layer glycoprotein
D      Natgr_2249 PGF-CTERM archaeal protein-sorting signal	K26284 csg; S-layer glycoprotein
D      Natgr_2248 PGF-CTERM archaeal protein-sorting signal	K26284 csg; S-layer glycoprotein
C    99994 Others
D      Natgr_0346 phosphate transport system regulatory protein PhoU	K02039 phoU; phosphate transport system protein
D      Natgr_2796 phosphate transport system regulatory protein PhoU	K02039 phoU; phosphate transport system protein
D      Natgr_2436 phosphate transport system regulatory protein PhoU	K02039 phoU; phosphate transport system protein
D      Natgr_2936 uncharacterized protein involved in tolerance to divalent cations	K03926 cutA; periplasmic divalent cation tolerance protein
D      Natgr_2393 nitrous oxidase accessory protein	K07218 nosD; nitrous oxidase accessory protein
D      Natgr_3199 molybdenum cofactor synthesis domain protein	K03750 moeA; molybdopterin molybdotransferase [EC:2.10.1.1]
D      Natgr_2387 putative lipoprotein involved in nitrous oxide reduction	K19342 nosL; copper chaperone NosL
B
B  09194 Poorly characterized
C    99996 General function prediction only
D      Natgr_2323 ATPase (PilT family)	K06865 K06865; ATPase
D      Natgr_3363 helicase family protein with metal-binding cysteine cluster	K06877 K06877; DEAD/DEAH box helicase domain-containing protein
D      Natgr_2396 EMAP domain-containing protein	K06878 K06878; tRNA-binding protein
D      Natgr_1035 haloacid dehalogenase superfamily enzyme, subfamily IA	K07025 K07025; putative hydrolase of the HAD superfamily
D      Natgr_0570 FeS assembly protein SufB	K09014 sufB; Fe-S cluster assembly protein SufB
D      Natgr_2080 FeS assembly protein SufB	K09014 sufB; Fe-S cluster assembly protein SufB
D      Natgr_0571 FeS assembly protein SufD	K09015 sufD; Fe-S cluster assembly protein SufD
D      Natgr_0393 putative membrane-bound metal-dependent hydrolase	K07038 K07038; inner membrane protein
D      Natgr_3713 putative metal-dependent hydrolase (urease superfamily)	K07049 K07049; TatD-related deoxyribonuclease
D      Natgr_3224 putative membrane protein	K07058 K07058; membrane protein
D      Natgr_3757 putative membrane protein	K07058 K07058; membrane protein
D      Natgr_2340 putative membrane protein	K07058 K07058; membrane protein
D      Natgr_3570 putative phosphoribosyltransferase	K07100 K07100; putative phosphoribosyl transferase
D      Natgr_1164 protein affecting phage T7 exclusion by the F plasmid	K07113 fxsA; UPF0716 protein FxsA
D      Natgr_0247 putative membrane protein	K08971 K08971; putative membrane protein
D      Natgr_0777 putative membrane protein	K08974 K08974; putative membrane protein
D      Natgr_0659 putative membrane protein	K08975 K08975; putative membrane protein
D      Natgr_1988 putative membrane protein	K08975 K08975; putative membrane protein
D      Natgr_0446 putative membrane protein	K08976 K08976; putative membrane protein
D      Natgr_2175 putative membrane protein	K08976 K08976; putative membrane protein
D      Natgr_0013 putative membrane protein	K08981 K08981; putative membrane protein
C    99997 Function unknown
D      Natgr_0335 ATP-grasp superfamily enzyme	K06869 K06869; uncharacterized protein
D      Natgr_3231 protein with phosphotransacetylase BioD-like N-terminal domain	K06873 K06873; uncharacterized protein
D      Natgr_1369 HD superfamily phosphohydrolase	K06885 K06885; uncharacterized protein
D      Natgr_3290 HD superfamily phosphohydrolase	K06885 K06885; uncharacterized protein
D      Natgr_1163 thioredoxin domain protein	K06888 K06888; uncharacterized protein
D      Natgr_3356 thioredoxin domain protein	K06888 K06888; uncharacterized protein
D      Natgr_0627 hypothetical protein	K06929 K06929; uncharacterized protein
D      Natgr_1448 putative DNA-binding protein with PD1-like DNA-binding motif	K06934 K06934; uncharacterized protein
D      Natgr_0785 putative Fe-S oxidoreductase	K06940 K06940; uncharacterized protein
D      Natgr_2195 Uncharacterized protein family (UPF0153)	K06940 K06940; uncharacterized protein
D      Natgr_0828 putative domain HDIG-containing protein	K06950 K06950; uncharacterized protein
D      Natgr_1521 putative domain HDIG-containing protein	K06950 K06950; uncharacterized protein
D      Natgr_0901 putative phosphoesterase, ICC	K06953 K06953; uncharacterized protein
D      Natgr_0603 putative phosphoesterase, ICC	K06953 K06953; uncharacterized protein
D      Natgr_0248 membrane complex biogenesis protein, BtpA family	K06971 K06971; uncharacterized protein
D      Natgr_1997 putative deacylase	K06987 K06987; uncharacterized protein
D      Natgr_1172 putative deacylase	K06987 K06987; uncharacterized protein
D      Natgr_0236 putative RND superfamily exporter	K07003 K07003; uncharacterized protein
D      Natgr_0481 putative RND superfamily exporter	K07003 K07003; uncharacterized protein
D      Natgr_2742 putative RND superfamily exporter	K07003 K07003; uncharacterized protein
D      Natgr_2061 putative RND superfamily exporter	K07003 K07003; uncharacterized protein
D      Natgr_3327 putative flavin-nucleotide-binding protein	K07005 K07005; uncharacterized protein
D      Natgr_1068 putative flavin-nucleotide-binding protein	K07005 K07005; uncharacterized protein
D      Natgr_0640 putative flavin-nucleotide-binding protein	K07005 K07005; uncharacterized protein
D      Natgr_2696 putative hydrolase of the alpha/beta superfamily	K07018 K07018; uncharacterized protein
D      Natgr_2527 KH-domain/beta-lactamase-domain protein	K07041 K07041; uncharacterized protein
D      Natgr_0775 putative TIM-barrel fold metal-dependent hydrolase	K07045 K07045; uncharacterized protein
D      Natgr_1264 putative TIM-barrel fold metal-dependent hydrolase	K07045 K07045; uncharacterized protein
D      Natgr_2188 putative TIM-barrel fold metal-dependent hydrolase	K07045 K07045; uncharacterized protein
D      Natgr_0425 putative nucleic-acid-binding protein containing a Zn-ribbon	K07068 K07068; uncharacterized protein
D      Natgr_3495 putative nucleic-acid-binding protein containing a Zn-ribbon	K07068 K07068; uncharacterized protein
D      Natgr_0824 putative nucleic-acid-binding protein containing a Zn-ribbon	K07068 K07068; uncharacterized protein
D      Natgr_1191 putative nucleotidyltransferase	K07074 K07074; uncharacterized protein
D      Natgr_3051 putative permease	K07089 K07089; uncharacterized protein
D      Natgr_3035 putative permease	K07090 K07090; uncharacterized protein
D      Natgr_3151 putative permease	K07090 K07090; uncharacterized protein
D      Natgr_1819 phosphoesterase, MJ0936 family	K07095 K07095; uncharacterized protein
D      Natgr_1732 phosphoesterase, MJ0936 family	K07095 K07095; uncharacterized protein
D      Natgr_1912 putative DHD superfamily phosphohydrolase	K07097 K07097; uncharacterized protein
D      Natgr_2961 putative phosphoribosyltransferase	K07101 K07101; uncharacterized protein
D      Natgr_1420 putative regulator of amino acid metabolism, contains ACT domain	K07103 K07103; uncharacterized protein
D      Natgr_0548 putative transporter component	K07112 K07112; uncharacterized protein
D      Natgr_0549 putative transporter component	K07112 K07112; uncharacterized protein
D      Natgr_0280 putative transporter component	K07112 K07112; uncharacterized protein
D      Natgr_0281 putative transporter component	K07112 K07112; uncharacterized protein
D      Natgr_1987 hypothetical protein	K07129 K07129; uncharacterized protein
D      Natgr_2169 putative Fe-S protein	K07140 K07140; MOSC domain-containing protein
D      Natgr_1131 putative membrane protein	K07148 K07148; uncharacterized protein
D      Natgr_2314 PilT domain protein	K07158 K07158; uncharacterized protein
D      Natgr_0789 TIGR00162 family protein	K07159 K07159; uncharacterized protein
D      Natgr_1597 Zn-ribbon containing protein (DUF2072)	K07163 K07163; uncharacterized protein
D      Natgr_2023 hypothetical protein	K08999 K08999; uncharacterized protein
D      Natgr_0337 hypothetical protein	K09005 K09005; uncharacterized protein
D      Natgr_1312 hypothetical protein	K09005 K09005; uncharacterized protein
D      Natgr_2014 hypothetical protein	K09120 K09120; uncharacterized protein
D      Natgr_2050 hypothetical protein	K09122 K09122; uncharacterized protein
D      Natgr_1285 uncharacterized protein, PH0010 family	K09141 K09141; uncharacterized protein
D      Natgr_2281 hypothetical protein	K09141 K09141; uncharacterized protein
D      Natgr_1525 hypothetical protein	K09148 K09148; uncharacterized protein
D      Natgr_1759 hypothetical protein	K09150 K09150; uncharacterized protein
D      Natgr_3704 hypothetical protein	K09152 K09152; uncharacterized protein
D      Natgr_3783 hypothetical protein	K09154 K09154; uncharacterized protein
D      Natgr_0498 hypothetical protein	K09163 K09163; uncharacterized protein
D      Natgr_1645 hypothetical protein	K09164 K09164; uncharacterized protein
D      Natgr_0012 hypothetical protein	K09167 K09167; uncharacterized protein
D      Natgr_2355 hypothetical protein	K09713 K09713; uncharacterized protein
D      Natgr_2972 hypothetical protein	K09726 K09726; uncharacterized protein
D      Natgr_3091 hypothetical protein	K09726 K09726; uncharacterized protein
D      Natgr_3696 hypothetical protein	K09728 K09728; uncharacterized protein
D      Natgr_2819 hypothetical protein	K09730 K09730; uncharacterized protein
D      Natgr_3621 hypothetical protein	K09731 K09731; uncharacterized protein
D      Natgr_0382 hypothetical protein	K09731 K09731; uncharacterized protein
D      Natgr_1516 hypothetical protein	K09732 K09732; uncharacterized protein
D      Natgr_1554 hypothetical protein	K09736 K09736; uncharacterized protein
D      Natgr_2537 hypothetical protein	K09738 K09738; uncharacterized protein
D      Natgr_1596 hypothetical protein	K09743 K09743; uncharacterized protein
D      Natgr_3620 hypothetical protein	K09744 K09744; uncharacterized protein
D      Natgr_0604 hypothetical protein	K09746 K09746; uncharacterized protein
D      Natgr_1302 hypothetical protein	K09746 K09746; uncharacterized protein
D      Natgr_0283 hypothetical protein	K09763 K09763; uncharacterized protein
D      Natgr_1321 hypothetical protein	K09763 K09763; uncharacterized protein
D      Natgr_2823 hypothetical protein	K09786 K09786; uncharacterized protein
D      Natgr_0849 hypothetical protein	K09791 K09791; uncharacterized protein
D      Natgr_2385 hypothetical protein	K09792 K09792; uncharacterized protein
D      Natgr_2867 hypothetical protein	K09792 K09792; uncharacterized protein
D      Natgr_2574 hypothetical protein	K09793 K09793; uncharacterized protein
D      Natgr_0997 hypothetical protein	K09807 K09807; uncharacterized protein
D      Natgr_0578 hypothetical protein	K09928 K09928; uncharacterized protein
D      Natgr_1846 hypothetical protein	K09961 K09961; uncharacterized protein
D      Natgr_2307 hypothetical protein	K09966 K09966; uncharacterized protein
D      Natgr_3492 putative exonuclease	K07502 yprB; uncharacterized protein
!
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#Last updated: May 10, 2024