+E Replication protein KO
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DNA Replication Proteins - Neisseria lactamica
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AEukaryotic type
B DNA Replication Initiation Factors
C pre-RC (pre-replication complex)
C CDK (cyclin dependent kinase)
C DDK (Dbf-4 dependent kinase)
C GINS complex
C Other initiation factors
B DNA Replication Elongation Factors
C DNA polymerase alpha / primase complex
C DNA polymerase epsilon complex
C DNA polymerase delta complex
C DNA polymerase gamma complex (mitochondrial)
C RPA (replication protein A)
C RFC (replication factor C)
C RNase H
D NLA_6530 rnhA; ribonuclease HI K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
C Other elongation factors
B DNA Replication Termination Factors
C DNA methylation enzymes
D NLA_6870 C-5 cytosine-specific DNA methylase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D NLA_1720 nlaXM; cytosine-specific methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D NLA_10840 DNA modification methylase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D NLA_12990 DNA cytosine methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D NLA_19510 putative DNA modification methylase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D NLA_15070 C-5 cytosine-specific DNA-methylase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D NLA_14100 nmgII; putative modification methylase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
C Prevention of re-replication factors
C Telomere proteins
D Shelterin complex
D TERB1-TERB2-MAJIN complex
D CST complex (animals)
D CST complex (yeast)
D RIF proteins
D SIR proteins
C Telomerase complex (animals)
D Dyskerin complex
C Telomerase complex (fungi)
D Sm core complex
C ELG1-RFC complex
C MRN complex
C Other termination factors
B DNA Topoisomerases
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AProkaryotic type
B DNA Replication Initiation Factors
C Initiation factors (bacterial)
D NLA_10360 hupB; putative DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
D NLA_3100 hupB2; dna-binding protein HU-beta 2 K03530 hupB; DNA-binding protein HU-beta
D NLA_15050 himA; putative integration host factor alpha-subunit K04764 ihfA; integration host factor subunit alpha
D NLA_11370 hip; integration host factor beta-subunit K05788 ihfB; integration host factor subunit beta
D NLA_18460 dnaA; putative chromosomal replication initiator protein K02313 dnaA; chromosomal replication initiator protein
D NLA_13540 dnaB; putative replicative DNA helicase K02314 dnaB; replicative DNA helicase [EC:5.6.2.3]
D NLA_7400 dnaG; DNA primase K02316 dnaG; DNA primase [EC:2.7.7.101]
D NLA_8130 ssb; single-stranded binding protein K03111 ssb; single-strand DNA-binding protein
C Initiation factors (archaeal)
B DNA Replication Elongation Factors
C Elongation factors (bacterial)
D DNA polymerase III holoenzyme
E NLA_17650 dnaE; putative DNA polymerase III, alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E NLA_18450 dnaN; putative DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E NLA_7150 holC; DNA polymerase III chi subunit K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
E NLA_15260 holA; putative DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E NLA_14610 holB; putative DNA polymerase III, delta' subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E NLA_8760 putative DNA polymerase III subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E NLA_7650 dnaQ; DNA polymerase III, epsilon chain K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E NLA_12580 dnaZX; DNA polymerase III tau and gamma chains K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D RNase H
E NLA_6530 rnhA; ribonuclease HI K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
E NLA_1520 rnhB; ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4]
D Other elongation factors
E NLA_19210 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E NLA_15760 ligA; putative DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
C Elongation factors (archaeal)
D B-family DNA polymerases
D D-family DNA polymerases
D RNase H
E NLA_6530 rnhA; ribonuclease HI K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
E NLA_1520 rnhB; ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4]
D RFC (replication factor C)
D Other elongation factors
B DNA Replication Termination Factors
C Terminus site-binding protein
C DNA methylation enzymes
D NLA_3400 putative adenine specific dna methyltransferase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
C Prevention of re-replication factors
D NLA_9620 hypothetical protein K10763 hda; DnaA-homolog protein
B DNA Topoisomerases
C NLA_12290 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
C NLA_1740 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
C NLA_6830 parC; DNA topoisomerase IV subunit A K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2]
C NLA_6000 parE; topoisomerase IV subunit B K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2]
C NLA_0580 topA; DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: November 2, 2022