+E Replication protein KO
#
DNA Replication Proteins - Oncorhynchus mykiss (rainbow trout)
%
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AEukaryotic type
B DNA Replication Initiation Factors
C pre-RC (pre-replication complex)
D 110524757 orc1; origin recognition complex subunit 1 isoform X1 K02603 ORC1; origin recognition complex subunit 1
D 110530863 orc2; origin recognition complex subunit 2 isoform X1 K02604 ORC2; origin recognition complex subunit 2
D 110498130 orc3; origin recognition complex subunit 3 isoform X1 K02605 ORC3; origin recognition complex subunit 3
D 110495382 origin recognition complex subunit 4 K02606 ORC4; origin recognition complex subunit 4
D 110491192 origin recognition complex subunit 4-like K02606 ORC4; origin recognition complex subunit 4
D 110490475 orc5; origin recognition complex subunit 5 K02607 ORC5; origin recognition complex subunit 5
D 110499992 origin recognition complex subunit 5 K02607 ORC5; origin recognition complex subunit 5
D 110506365 orc6; origin recognition complex subunit 6 isoform X1 K02608 ORC6; origin recognition complex subunit 6
D 110506411 DNA replication factor Cdt1 isoform X1 K10727 CDT1; chromatin licensing and DNA replication factor 1
D 110526297 DNA replication factor Cdt1 K10727 CDT1; chromatin licensing and DNA replication factor 1
D 110485889 cdc6; cell division control protein 6 homolog isoform X1 K02213 CDC6; cell division control protein 6
D 110493611 cell division control protein 6 homolog K02213 CDC6; cell division control protein 6
D 110528595 DNA replication licensing factor mcm2 K02540 MCM2; DNA replication licensing factor MCM2 [EC:5.6.2.3]
D 110493296 DNA replication licensing factor mcm2 K02540 MCM2; DNA replication licensing factor MCM2 [EC:5.6.2.3]
D 110529168 mcm3; DNA replication licensing factor MCM3 isoform X1 K02541 MCM3; DNA replication licensing factor MCM3 [EC:5.6.2.3]
D 110524650 mcm3l; MCM3 minichromosome maintenance deficient 3 (S. cerevisiae), like K02541 MCM3; DNA replication licensing factor MCM3 [EC:5.6.2.3]
D 110508600 DNA replication licensing factor mcm4-A K02212 MCM4; DNA replication licensing factor MCM4 [EC:5.6.2.3]
D 110530465 DNA replication licensing factor mcm4 K02212 MCM4; DNA replication licensing factor MCM4 [EC:5.6.2.3]
D 110538499 mcm5; DNA replication licensing factor mcm5 K02209 MCM5; DNA replication licensing factor MCM5 [EC:5.6.2.3]
D 110486535 DNA replication licensing factor mcm5 K02209 MCM5; DNA replication licensing factor MCM5 [EC:5.6.2.3]
D 110508155 DNA replication licensing factor MCM6 K02542 MCM6; DNA replication licensing factor MCM6 [EC:5.6.2.3]
D 110530373 mcm6l; MCM6 minichromosome maintenance deficient 6, like isoform X2 K02542 MCM6; DNA replication licensing factor MCM6 [EC:5.6.2.3]
D 110530628 zygotic DNA replication licensing factor mcm6-B K02542 MCM6; DNA replication licensing factor MCM6 [EC:5.6.2.3]
D 110489022 mcm7; DNA replication licensing factor MCM7 K02210 MCM7; DNA replication licensing factor MCM7 [EC:5.6.2.3]
C CDK (cyclin dependent kinase)
D 110488948 cyclin-A2 K06627 CCNA; cyclin-A
D 110510255 ccna1; cyclin-A1 K06627 CCNA; cyclin-A
D 110505148 cyclin-A2 K06627 CCNA; cyclin-A
D 110513832 G1/S-specific cyclin-E2 K06626 CCNE; G1/S-specific cyclin-E1
D 110506376 G1/S-specific cyclin-E1 isoform X1 K06626 CCNE; G1/S-specific cyclin-E1
D 110486705 G1/S-specific cyclin-E2 isoform X1 K06626 CCNE; G1/S-specific cyclin-E1
D 110526255 ccne1; G1/S-specific cyclin-E1 K06626 CCNE; G1/S-specific cyclin-E1
D 110528231 cdk2; cyclin-dependent kinase 2 K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
D 110494209 cyclin-dependent kinase 2 isoform X1 K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
C DDK (Dbf-4 dependent kinase)
D 110508951 cdc7; cell division cycle 7-related protein kinase isoform X1 K02214 CDC7; cell division control protein 7 [EC:2.7.11.1]
D 110535823 protein DBF4 homolog A K06629 DBF4; protein DBF4
D 110507732 protein DBF4 homolog A isoform X1 K06629 DBF4; protein DBF4
D 110491667 dbf4b; uncharacterized protein dbf4b K06629 DBF4; protein DBF4
C GINS complex
D 110527577 gins1; DNA replication complex GINS protein PSF1 K10732 GINS1; GINS complex subunit 1
D 110525047 DNA replication complex GINS protein PSF2-like K10733 GINS2; GINS complex subunit 2
D 110506613 DNA replication complex GINS protein PSF2 K10733 GINS2; GINS complex subunit 2
D 110494044 gins3; DNA replication complex GINS protein PSF3 K10734 GINS3; GINS complex subunit 3
D 110536039 DNA replication complex GINS protein SLD5 K10735 GINS4; GINS complex subunit 4
D 110525671 DNA replication complex GINS protein SLD5 K10735 GINS4; GINS complex subunit 4
C Other initiation factors
D 110489895 topbp1; DNA topoisomerase 2-binding protein 1 K10728 TOPBP1; topoisomerase (DNA) II binding protein 1
D 110496667 recql4; ATP-dependent DNA helicase Q4 isoform X1 K10730 RECQL4; ATP-dependent DNA helicase Q4 [EC:5.6.2.4]
D 110536195 cdc45; cell division control protein 45 homolog K06628 CDC45; cell division control protein 45
D 110497801 mcm8; DNA helicase MCM8 isoform X1 K10737 MCM8; DNA helicase MCM8 [EC:5.6.2.4]
D 110529584 mcm9; DNA helicase MCM9 K10738 MCM9; DNA helicase MCM9 [EC:5.6.2.4]
D 110500141 mcm10; protein MCM10 homolog K10736 MCM10; minichromosome maintenance protein 10
D 110513781 DNA helicase B isoform X1 K15254 HELB; DNA helicase B [EC:5.6.2.3]
D 110499740 helb; DNA helicase B K15254 HELB; DNA helicase B [EC:5.6.2.3]
D 110530884 protein FAM111A isoform X1 K24274 FAM111A; protein FAM111A
D 110514977 protein FAM111A K24274 FAM111A; protein FAM111A
D 118938855 protein FAM111A-like K24274 FAM111A; protein FAM111A
D 118938856 protein FAM111B-like K24274 FAM111A; protein FAM111A
D 118942835 protein FAM111A-like K24274 FAM111A; protein FAM111A
D 118942836 protein FAM111A-like K24274 FAM111A; protein FAM111A
D 110505757 cyclin-dependent kinase 2-interacting protein isoform X4 K26052 CINP; cyclin-dependent kinase 2-interacting protein
D 110520696 mdm2-binding protein isoform X1 K26116 MTBP; Mdm2-binding protein
D 110522723 treslin isoform X1 K26117 TICRR; Treslin
B DNA Replication Elongation Factors
C DNA polymerase alpha / primase complex
D 110535443 pola1; DNA polymerase alpha catalytic subunit K02320 POLA1; DNA polymerase alpha subunit A [EC:2.7.7.7]
D 110489044 pola2; DNA polymerase alpha subunit B K02321 POLA2; DNA polymerase alpha subunit B
D 110492372 prim1; DNA primase small subunit K02684 PRI1; DNA primase small subunit [EC:2.7.7.102]
D 110502683 prim2; DNA primase large subunit K02685 PRI2; DNA primase large subunit
C DNA polymerase epsilon complex
D 110535757 pole; DNA polymerase epsilon catalytic subunit A K02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
D 110498188 pole2; DNA polymerase epsilon subunit 2 K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
D 110523234 pole3; DNA polymerase epsilon subunit 3 K02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
D 110502819 DNA polymerase epsilon subunit 4 K03506 POLE4; DNA polymerase epsilon subunit 4 [EC:2.7.7.7]
D 110524218 DNA polymerase epsilon subunit 4 isoform X1 K03506 POLE4; DNA polymerase epsilon subunit 4 [EC:2.7.7.7]
C DNA polymerase delta complex
D 110534257 DNA polymerase delta catalytic subunit-like K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
D 110487419 DNA polymerase delta catalytic subunit K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
D 110535104 pold2; DNA polymerase delta subunit 2 isoform X1 K02328 POLD2; DNA polymerase delta subunit 2
D 110534039 pold3; DNA polymerase delta subunit 3 isoform X1 K03504 POLD3; DNA polymerase delta subunit 3
D 100301737 pold4; DNA polymerase delta subunit 4 K03505 POLD4; DNA polymerase delta subunit 4
C DNA polymerase gamma complex (mitochondrial)
D 110522581 polg; DNA polymerase subunit gamma-1 K02332 POLG; DNA polymerase gamma 1 [EC:2.7.7.7]
D 110493679 polg2; DNA polymerase subunit gamma-2, mitochondrial K02333 POLG2; DNA polymerase gamma 2
C RPA (replication protein A)
D 110503940 rpa1; replication protein A 70 kDa DNA-binding subunit isoform X1 K07466 RFA1; replication factor A1
D 110507776 replication protein A 70 kDa DNA-binding subunit isoform X1 K07466 RFA1; replication factor A1
D 110489231 replication protein A 32 kDa subunit isoform X1 K10739 RFA2; replication factor A2
D 110496416 replication protein A 32 kDa subunit-A K10739 RFA2; replication factor A2
D 110517694 rpa2; replication protein A 32 kDa subunit K10739 RFA2; replication factor A2
D 100305185 rfa3; Replication protein A 14 kDa subunit K10740 RPA3; replication factor A3
D 110488133 replication protein A 14 kDa subunit K10740 RPA3; replication factor A3
C RFC (replication factor C)
D 110511546 replication factor C subunit 1 K10754 RFC1; replication factor C subunit 1
D 110515655 replication factor C subunit 1 K10754 RFC1; replication factor C subunit 1
D 110521582 replication factor C subunit 4 isoform X1 K10755 RFC2_4; replication factor C subunit 2/4
D 110524454 replication factor C subunit 4 isoform X1 K10755 RFC2_4; replication factor C subunit 2/4
D 110533538 rfc2; replication factor C subunit 2 isoform X1 K10755 RFC2_4; replication factor C subunit 2/4
D 118966692 rfc3; replication factor C subunit 3 K10756 RFC3_5; replication factor C subunit 3/5
D 110536382 rfc5; replication factor C subunit 5 K10756 RFC3_5; replication factor C subunit 3/5
C RNase H
D 110529818 ribonuclease H1 isoform X1 K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D 100305327 rnh1; Ribonuclease H1 K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D 110486088 ribonuclease H2 subunit A K10743 RNASEH2A; ribonuclease H2 subunit A [EC:3.1.26.4]
D 118938208 ribonuclease H2 subunit A-like K10743 RNASEH2A; ribonuclease H2 subunit A [EC:3.1.26.4]
D 110520519 rnaseh2b; ribonuclease H2 subunit B isoform X1 K10744 RNASEH2B; ribonuclease H2 subunit B
D 100301719 rnaseh2c; ribonuclease H2 subunit C K10745 RNASEH2C; ribonuclease H2 subunit C
C Other elongation factors
D 110536211 proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
D 110523712 proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
D 110523713 proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
D 110525832 proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
D 110502736 dna2; DNA replication ATP-dependent helicase/nuclease DNA2 K10742 DNA2; DNA replication ATP-dependent helicase/nuclease Dna2 [EC:5.6.2.3 3.1.-.-]
D 110535235 flap endonuclease 1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D 110530008 zgc:110269; probable flap endonuclease 1 homolog isoform X1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D 110528185 exo1; exonuclease 1 K10746 EXO1; exonuclease 1 [EC:3.1.-.-]
D 110528847 DNA annealing helicase and endonuclease ZRANB3-like K25861 ZRANB3; DNA annealing helicase and endonuclease ZRANB3 [EC:5.6.2.- 3.1.-.-]
D 110496980 DNA annealing helicase and endonuclease ZRANB3 K25861 ZRANB3; DNA annealing helicase and endonuclease ZRANB3 [EC:5.6.2.- 3.1.-.-]
D 110531014 lig1; LOW QUALITY PROTEIN: DNA ligase 1 K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
D 110538914 ATPase family AAA domain-containing protein 5 K26118 ATAD5; ATPase family AAA domain-containing protein 5
D 110493570 ATPase family AAA domain-containing protein 5 isoform X1 K26118 ATAD5; ATPase family AAA domain-containing protein 5
D 110486913 ATPase family AAA domain-containing protein 5 K26118 ATAD5; ATPase family AAA domain-containing protein 5
B DNA Replication Termination Factors
C DNA methylation enzymes
D 110538418 DNA (cytosine-5)-methyltransferase 1 isoform X1 K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D 110486372 DNA (cytosine-5)-methyltransferase 1 isoform X1 K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D 110497603 DNA (cytosine-5)-methyltransferase 3A isoform X1 K17398 DNMT3A; DNA (cytosine-5)-methyltransferase 3A [EC:2.1.1.37]
D 110531067 DNA (cytosine-5)-methyltransferase 3A isoform X1 K17398 DNMT3A; DNA (cytosine-5)-methyltransferase 3A [EC:2.1.1.37]
D 110505844 DNA (cytosine-5)-methyltransferase 3A isoform X1 K17398 DNMT3A; DNA (cytosine-5)-methyltransferase 3A [EC:2.1.1.37]
D 110492301 dnmt3bb.1; DNA (cytosine-5)-methyltransferase 3B isoform X9 K17399 DNMT3B; DNA (cytosine-5)-methyltransferase 3B [EC:2.1.1.37]
D 110492303 uncharacterized protein LOC110492303 K17399 DNMT3B; DNA (cytosine-5)-methyltransferase 3B [EC:2.1.1.37]
D 110492746 uncharacterized protein LOC110492746 isoform X1 K17399 DNMT3B; DNA (cytosine-5)-methyltransferase 3B [EC:2.1.1.37]
D 110532104 DNA (cytosine-5)-methyltransferase 3B isoform X1 K17399 DNMT3B; DNA (cytosine-5)-methyltransferase 3B [EC:2.1.1.37]
D 110532515 DNA (cytosine-5)-methyltransferase 3A isoform X2 K17399 DNMT3B; DNA (cytosine-5)-methyltransferase 3B [EC:2.1.1.37]
C Prevention of re-replication factors
D 110496552 geminin K10749 GMNN; geminin
D 110487922 geminin K10749 GMNN; geminin
D 110525074 multicilin K26119 MCIDAS; multicilin
D 100136690 cyclin B1 K05868 CCNB1; G2/mitotic-specific cyclin-B1
D 110523559 G2/mitotic-specific cyclin-B1 K05868 CCNB1; G2/mitotic-specific cyclin-B1
D 110506456 G2/mitotic-specific cyclin-B1 K05868 CCNB1; G2/mitotic-specific cyclin-B1
D 100136691 cyclin B2 K21770 CCNB2; G2/mitotic-specific cyclin-B2
D 110506532 G2/mitotic-specific cyclin-B2 isoform X1 K21770 CCNB2; G2/mitotic-specific cyclin-B2
D 110507995 ccnp; cyclin N-terminal domain-containing protein 2 K21770 CCNB2; G2/mitotic-specific cyclin-B2
D 110510157 G2/mitotic-specific cyclin-B3 K21771 CCNB3; G2/mitotic-specific cyclin-B3
D 110531416 ccnb3; G2/mitotic-specific cyclin-B3 K21771 CCNB3; G2/mitotic-specific cyclin-B3
D 110502539 cyclin-dependent kinase 1 isoform X1 K02087 CDK1; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
D 100136692 Cdc2 kinase K02087 CDK1; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
C Telomere proteins
D Shelterin complex
E 110521332 pot1; protection of telomeres protein 1 isoform X1 K11109 POT1; protection of telomeres protein 1
E 110535179 terf1; telomeric repeat-binding factor 1 K11110 TERF1; telomeric repeat-binding factor 1
E 110504960 terfa; telomeric repeat binding factor a isoform X1 K11111 TERF2; telomeric repeat-binding factor 2
E 110503123 uncharacterized protein LOC110503123 K11112 TINF2; TERF1-interacting nuclear factor 2
E 110531630 uncharacterized protein LOC110531630 isoform X1 K11112 TINF2; TERF1-interacting nuclear factor 2
E 110500487 tinf2; TERF1-interacting nuclear factor 2 isoform X1 K11112 TINF2; TERF1-interacting nuclear factor 2
E 110528641 telomeric repeat-binding factor 2-interacting protein 1 isoform X1 K11113 TERF2IP; telomeric repeat-binding factor 2-interacting protein 1
E 110506564 acd; adrenocortical dysplasia protein homolog isoform X1 K11114 ACD; adrenocortical dysplasia protein
D TERB1-TERB2-MAJIN complex
E 110521298 terb1; telomere repeats-binding bouquet formation protein 1 isoform X1 K25749 TERB1; telomere repeats-binding bouquet formation protein 1
E 110496029 uncharacterized protein LOC110496029 isoform X1 K25749 TERB1; telomere repeats-binding bouquet formation protein 1
E 110525043 terb2; telomere repeats-binding bouquet formation protein 2 K25750 TERB2; telomere repeats-binding bouquet formation protein 2
E 110532903 uncharacterized protein LOC110532903 K25751 MAJIN; membrane-anchored junction protein
D CST complex (animals)
E 110498368 ctc1; CST complex subunit CTC1 K23311 CTC1; CST complex subunit CTC1
E 110493535 stn1; CST complex subunit STN1 isoform X1 K23312 STN1; CST complex subunit STN1
E 110487299 LOW QUALITY PROTEIN: CST complex subunit STN1 K23312 STN1; CST complex subunit STN1
E 110495138 CST complex subunit TEN1 K23313 TEN1; CST complex subunit TEN1
E 110485954 CST complex subunit TEN1 K23313 TEN1; CST complex subunit TEN1
D CST complex (yeast)
D RIF proteins
D SIR proteins
C Telomerase complex (animals)
D 110510236 telomerase-binding protein EST1A isoform X1 K11124 SMG6; protein SMG6 [EC:3.1.-.-]
D 110492806 smg6; telomerase-binding protein EST1A isoform X1 K11124 SMG6; protein SMG6 [EC:3.1.-.-]
D 110515194 protein SMG5 K11125 SMG5; protein SMG5
D 110487742 smg5; protein SMG5 K11125 SMG5; protein SMG5
D 110487844 tert; telomerase reverse transcriptase isoform X1 K11126 TERT; telomerase reverse transcriptase [EC:2.7.7.49]
D 110530561 tep1; telomerase protein component 1 K11127 TEP1; telomerase protein component 1
D Dyskerin complex
E 110488920 H/ACA ribonucleoprotein complex subunit 1 K11128 GAR1; H/ACA ribonucleoprotein complex subunit 1
E 110505115 H/ACA ribonucleoprotein complex subunit 1 K11128 GAR1; H/ACA ribonucleoprotein complex subunit 1
E 110537797 H/ACA ribonucleoprotein complex subunit 2-like protein K11129 NHP2; H/ACA ribonucleoprotein complex subunit 2
E 110533406 nhp2; H/ACA ribonucleoprotein complex subunit 2-like protein K11129 NHP2; H/ACA ribonucleoprotein complex subunit 2
E 100301851 nola3; H/ACA ribonucleoprotein complex subunit 3 K11130 NOP10; H/ACA ribonucleoprotein complex subunit 3
E 110500396 H/ACA ribonucleoprotein complex subunit 3 K11130 NOP10; H/ACA ribonucleoprotein complex subunit 3
E 110509933 H/ACA ribonucleoprotein complex subunit DKC1 isoform X1 K11131 DKC1; H/ACA ribonucleoprotein complex subunit 4 [EC:5.4.99.-]
E 110533950 H/ACA ribonucleoprotein complex subunit DKC1 isoform X1 K11131 DKC1; H/ACA ribonucleoprotein complex subunit 4 [EC:5.4.99.-]
C Telomerase complex (fungi)
D 110487844 tert; telomerase reverse transcriptase isoform X1 K11126 TERT; telomerase reverse transcriptase [EC:2.7.7.49]
D Sm core complex
E 110528556 snrpb; small nuclear ribonucleoprotein-associated proteins B and B' K11086 SNRPB; small nuclear ribonucleoprotein B and B'
E 110496512 snrpd1; small nuclear ribonucleoprotein Sm D1 K11087 SNRPD1; small nuclear ribonucleoprotein D1
E 110487904 small nuclear ribonucleoprotein Sm D1 isoform X1 K11087 SNRPD1; small nuclear ribonucleoprotein D1
E 110504020 snrpd2; small nuclear ribonucleoprotein Sm D2 K11096 SNRPD2; small nuclear ribonucleoprotein D2
E 110533417 small nuclear ribonucleoprotein Sm D2 isoform X2 K11096 SNRPD2; small nuclear ribonucleoprotein D2
E 110507846 small nuclear ribonucleoprotein Sm D2 K11096 SNRPD2; small nuclear ribonucleoprotein D2
E 110509725 small nuclear ribonucleoprotein Sm D3 K11088 SNRPD3; small nuclear ribonucleoprotein D3
E 100301801 smd3; Small nuclear ribonucleoprotein Sm D3 K11088 SNRPD3; small nuclear ribonucleoprotein D3
E 110525517 small nuclear ribonucleoprotein Sm D3 K11088 SNRPD3; small nuclear ribonucleoprotein D3
E 110528042 snrpe; small nuclear ribonucleoprotein E K11097 SNRPE; small nuclear ribonucleoprotein E
E 110494395 small nuclear ribonucleoprotein E K11097 SNRPE; small nuclear ribonucleoprotein E
E 100301729 ruxf; Small nuclear ribonucleoprotein F K11098 SNRPF; small nuclear ribonucleoprotein F
E 110490436 small nuclear ribonucleoprotein F K11098 SNRPF; small nuclear ribonucleoprotein F
E 110525078 small nuclear ribonucleoprotein F K11098 SNRPF; small nuclear ribonucleoprotein F
E 110500368 small nuclear ribonucleoprotein F K11098 SNRPF; small nuclear ribonucleoprotein F
E 110492664 snrpg; small nuclear ribonucleoprotein G K11099 SNRPG; small nuclear ribonucleoprotein G
E 110532786 small nuclear ribonucleoprotein G K11099 SNRPG; small nuclear ribonucleoprotein G
C ELG1-RFC complex
D 110521582 replication factor C subunit 4 isoform X1 K10755 RFC2_4; replication factor C subunit 2/4
D 110524454 replication factor C subunit 4 isoform X1 K10755 RFC2_4; replication factor C subunit 2/4
D 110533538 rfc2; replication factor C subunit 2 isoform X1 K10755 RFC2_4; replication factor C subunit 2/4
D 118966692 rfc3; replication factor C subunit 3 K10756 RFC3_5; replication factor C subunit 3/5
D 110536382 rfc5; replication factor C subunit 5 K10756 RFC3_5; replication factor C subunit 3/5
C MRN complex
D 110508026 mre11a; double-strand break repair protein MRE11 K10865 MRE11; double-strand break repair protein MRE11
D 110537777 rad50; DNA repair protein RAD50 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
D 110535897 nbn; nibrin isoform X1 K10867 NBN; nibrin
C Other termination factors
D 110503994 atm; serine-protein kinase ATM isoform X1 K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
D 110523180 wrn; Werner syndrome ATP-dependent helicase homolog isoform X1 K10900 WRN; werner syndrome ATP-dependent helicase [EC:5.6.2.4]
D 110495880 blm; Bloom syndrome protein homolog isoform X1 K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
D 110535300 prkdc; DNA-dependent protein kinase catalytic subunit K06642 PRKDC; DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1]
D 110499162 ercc4; DNA repair endonuclease XPF K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
D 110522422 parp1; poly [ADP-ribose] polymerase 1 K24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]
D 110501657 parp4; protein mono-ADP-ribosyltransferase PARP4 isoform X1 K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
D 110495181 protein mono-ADP-ribosyltransferase PARP3 K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
D 110530575 parp2; poly [ADP-ribose] polymerase 2 K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
D 118936263 parp3; protein mono-ADP-ribosyltransferase PARP3 K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
D 110536219 poly [ADP-ribose] polymerase tankyrase-1 isoform X1 K10799 TNKS; tankyrase [EC:2.4.2.30]
D 110523807 poly [ADP-ribose] polymerase tankyrase-1 isoform X1 K10799 TNKS; tankyrase [EC:2.4.2.30]
D 110537115 tnksa; poly [ADP-ribose] polymerase tankyrase-1 isoform X1 K10799 TNKS; tankyrase [EC:2.4.2.30]
D 110499002 poly [ADP-ribose] polymerase tankyrase-2 isoform X1 K10799 TNKS; tankyrase [EC:2.4.2.30]
D 110525835 poly [ADP-ribose] polymerase tankyrase-1 isoform X1 K10799 TNKS; tankyrase [EC:2.4.2.30]
D 110522658 pinx1; PIN2/TERF1-interacting telomerase inhibitor 1 isoform X2 K11135 PINX1; Pin2-interacting protein X1
D 110532187 rtel1; regulator of telomere elongation helicase 1 K11136 RTEL1; regulator of telomere elongation helicase 1 [EC:5.6.2.3]
D 110499074 telo2; telomere length regulation protein TEL2 homolog isoform X1 K11137 TELO2; telomere length regulation protein
D 110538477 telomerase RNA component interacting RNase K01149 TRIR; telomerase RNA component interacting RNase [EC:3.1.13.-]
D 110486518 telomerase RNA component interacting RNase K01149 TRIR; telomerase RNA component interacting RNase [EC:3.1.13.-]
D 110501816 telomere-associated protein RIF1 K11138 RIF1; telomere-associated protein RIF1
D 110520261 rif1; telomere-associated protein RIF1 isoform X1 K11138 RIF1; telomere-associated protein RIF1
D 110508935 pif1; ATP-dependent DNA helicase PIF1 isoform X2 K15255 PIF1; ATP-dependent DNA helicase PIF1 [EC:5.6.2.3]
D 110489085 transcriptional activator protein Pur-alpha K21772 PURA; transcriptional activator protein Pur-alpha
D 110510116 puraa; purine-rich element binding protein Aa K21772 PURA; transcriptional activator protein Pur-alpha
D 110504671 transcriptional activator protein Pur-alpha K21772 PURA; transcriptional activator protein Pur-alpha
D 110534119 transcriptional activator protein Pur-alpha K21772 PURA; transcriptional activator protein Pur-alpha
D 110509535 purine-rich element-binding protein gamma-like K21800 PURG; purine-rich element-binding protein gamma
D 110523182 purg; purine-rich element-binding protein gamma K21800 PURG; purine-rich element-binding protein gamma
D 110500516 wrap53; telomerase Cajal body protein 1 K23314 WRAP53; telomerase Cajal body protein 1
D 110493822 replication stress response regulator SDE2 K25059 SDE2; replication stress response regulator SDE2
D 110493823 replication stress response regulator SDE2 K25059 SDE2; replication stress response regulator SDE2
D 110528549 rtf2; replication termination factor 2 isoform X1 K25186 RTF2; replication termination factor 2
D 110493896 replication termination factor 2 isoform X1 K25186 RTF2; replication termination factor 2
B DNA Topoisomerases
C 110527908 DNA topoisomerase 1 K03163 TOP1; DNA topoisomerase I [EC:5.6.2.1]
C 110535255 top1mt; DNA topoisomerase I, mitochondrial isoform X1 K03163 TOP1; DNA topoisomerase I [EC:5.6.2.1]
C 110492527 DNA topoisomerase 1-like K03163 TOP1; DNA topoisomerase I [EC:5.6.2.1]
C 110494549 zgc:173742; DNA topoisomerase I, mitochondrial K03163 TOP1; DNA topoisomerase I [EC:5.6.2.1]
C 110494561 DNA topoisomerase 1 isoform X1 K03163 TOP1; DNA topoisomerase I [EC:5.6.2.1]
C 110496426 DNA topoisomerase 2-beta isoform X1 K03164 TOP2; DNA topoisomerase II [EC:5.6.2.2]
C 110491559 top2a; DNA topoisomerase 2-alpha K03164 TOP2; DNA topoisomerase II [EC:5.6.2.2]
C 110488151 DNA topoisomerase 2-beta isoform X1 K03164 TOP2; DNA topoisomerase II [EC:5.6.2.2]
C 110512919 DNA topoisomerase 3-alpha K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
C 110516858 DNA topoisomerase 3-alpha-like isoform X1 K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
C 110525187 top3b; DNA topoisomerase 3-beta-1 K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
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AProkaryotic type
B DNA Replication Initiation Factors
C Initiation factors (bacterial)
D 110490261 single-stranded DNA-binding protein, mitochondrial isoform X1 K03111 ssb; single-strand DNA-binding protein
D 110500213 single-stranded DNA-binding protein, mitochondrial K03111 ssb; single-strand DNA-binding protein
C Initiation factors (archaeal)
B DNA Replication Elongation Factors
C Elongation factors (bacterial)
D DNA polymerase III holoenzyme
D RNase H
E 110529818 ribonuclease H1 isoform X1 K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
E 100305327 rnh1; Ribonuclease H1 K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D Other elongation factors
C Elongation factors (archaeal)
D B-family DNA polymerases
D D-family DNA polymerases
D RNase H
E 110529818 ribonuclease H1 isoform X1 K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
E 100305327 rnh1; Ribonuclease H1 K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D RFC (replication factor C)
D Other elongation factors
E 110502736 dna2; DNA replication ATP-dependent helicase/nuclease DNA2 K10742 DNA2; DNA replication ATP-dependent helicase/nuclease Dna2 [EC:5.6.2.3 3.1.-.-]
E 110535235 flap endonuclease 1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
E 110530008 zgc:110269; probable flap endonuclease 1 homolog isoform X1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
E 110531014 lig1; LOW QUALITY PROTEIN: DNA ligase 1 K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
B DNA Replication Termination Factors
C Terminus site-binding protein
C DNA methylation enzymes
C Prevention of re-replication factors
B DNA Topoisomerases
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: November 2, 2022