+C Peptidases and inhibitors KO
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Peptidases and Inhibitors - Pseudomonas aeruginosa M18
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AAspartic peptidases
B Family A1: pepsin family
B Family A2: retropepsin family
B Family A5: thermopsin family
B Family A8: signal peptidase II family
C PAM18_4652 lspA; lipoprotein signal peptidase K03101 lspA; signal peptidase II [EC:3.4.23.36]
B Family A22: presenilin family
B Family A24: type IV prepilin peptidase family
C PAM18_4620 pilD; type 4 prepilin peptidase PilD K02654 pilD; leader peptidase (prepilin peptidase) / N-methyltransferase [EC:3.4.23.43 2.1.1.-]
C PAM18_4384 fppA; Flp prepilin peptidase A, FppA K02278 cpaA; prepilin peptidase CpaA [EC:3.4.23.43]
B Family A25: gpr protease family
B Family A26: omptin family
B Family A28
B Family A31: HybD endopeptidase family
B Family A36
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ACysteine peptidases
B Family C1: papain family
B Family C2: calpain family
B Family C3: picornain family
B Family C4: NIa protease family
B Family C5
B Family C9
B Family C10: streptopain family
B Family C11: clostripain family
B Family C12: ubiquitin C-terminal hydrolase family
B Family C13: legumain family
B Family C14: caspase family
B Family C15: pyroglutamyl peptidase I family
B Family C16
B Family C19: ubiquitin-specific protease family
B Family C25: gingipain family
B Family C26: gamma-glutamyl hydrolase family
C PAM18_1170 guaA; GMP synthase K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
C PAM18_0292 spuA; putative glutamine amidotransferase K07010 K07010; putative glutamine amidotransferase
B Family C27
B Family C30
B Family C37
B Family C39
C PAM18_0794 putative toxin transporter K13409 cvaB; ATP-binding cassette, subfamily B, bacterial CvaB/MchF/RaxB
B Family C40
C PAM18_1493 putative lipoprotein K19303 mepH; murein DD-endopeptidase [EC:3.4.-.-]
B Family C44
C PAM18_1855 purF; amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
C PAM18_5151 gltB; glutamate synthase subunit alpha K00265 gltB; glutamate synthase (NADPH) large chain [EC:1.4.1.13]
C PAM18_1186 putative aminotransferase K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
C PAM18_5677 glmS; glucosamine--fructose-6-phosphate aminotransferase K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
C PAM18_1506 putative glutamine amidotransferase K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]
C PAM18_0053 phzH; putative phenazine-modifying enzyme K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]
C PAM18_2959 putative asparagine synthetase K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]
C PAM18_5109 asparagine synthetase (glutamine-hydrolyzing) K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]
B Family C45
B Family C46: hedgehog family
B Family C47: staphopain family
B Family C48: Ulp1 endopeptidase family
B Family C50: separase family
B Family C54: Aut2 peptidase family
B Family C55: YopJ protease family
B Family C56: PfpI endopeptidase family
C PAM18_3897 chaperone protein HchA K05523 hchA; D-lactate dehydratase / protein deglycase [EC:4.2.1.130 3.5.1.124]
C PAM18_0353 pfpI; protease PfpI K05520 yhbO; deglycase [EC:3.5.1.124]
C PAM18_0766 putative protease K05520 yhbO; deglycase [EC:3.5.1.124]
C PAM18_4426 putative amidase/protease K05520 yhbO; deglycase [EC:3.5.1.124]
B Family C57: vaccinia virus I7 peptidase family
B Family C58
B Family C59
B Family C60
B Family C63
B Family C64
B Family C65
B Family C67
B Family C69
B Family C70
B Family C75
B Family C76
B Family C78
B Family C79
B Family C82
C PAM18_2109 putative ErfK/YbiS/YcfS/YnhG family protein K16291 erfK; L,D-transpeptidase ErfK/SrfK
B Family C83
B Family C85
B Family C86
B Family C88
B Family C89
B Family C97
B Family C98
B Family C110
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AGlutamic peptidases
B Family G1
B Family G4
B Family G5: prenyl protease 2 family
C PAM18_2079 putative protease K07052 K07052; CAAX protease family protein
C PAM18_5246 hypothetical protein K07052 K07052; CAAX protease family protein
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AMetallo peptidases
B Family M1
C PAM18_1880 pepN; aminopeptidase N K01256 pepN; aminopeptidase N [EC:3.4.11.2]
B Family M2
B Family M3
C PAM18_0068 prlC; oligopeptidase A K01414 prlC; oligopeptidase A [EC:3.4.24.70]
B Family M4: thermolysin family
C PAM18_1222 lasB; elastase LasB K01399 lasB; pseudolysin [EC:3.4.24.26]
B Family M5: mycolysin family
B Family M6: immune inhibitor A family
B Family M7: snapalysin family
B Family M8: leishmanolysin family
B Family M9
B Family M10
C PAM18_3782 aprA; alkaline metalloproteinase precursor K01406 prtC; serralysin [EC:3.4.24.40]
B Family M12: astacin/adamalysin family
B Family M13: neprilysin family
B Family M14: carboxypeptidase A family
B Family M15: zinc D-Ala-D-Ala carboxypeptidase family
C PAM18_1157 hypothetical protein K08641 vanX; zinc D-Ala-D-Ala dipeptidase [EC:3.4.13.22]
B Family M16: pitrilysin family
C PAM18_0371 putative zinc protease K07263 pqqL; zinc protease [EC:3.4.24.-]
C PAM18_0370 putative peptidase K07263 pqqL; zinc protease [EC:3.4.24.-]
B Family M17: leucyl aminopeptidase family
C PAM18_1107 pepA; leucyl aminopeptidase K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1]
B Family M18
B Family M19: membrane dipeptidase family
C PAM18_5515 putative dipeptidase K01273 DPEP; membrane dipeptidase [EC:3.4.13.19]
B Family M20
C PAM18_2176 cpg2; glutamate carboxypeptidase K01295 cpg; glutamate carboxypeptidase [EC:3.4.17.11]
C PAM18_3871 dapE; succinyl-diaminopimelate desuccinylase K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18]
C PAM18_2040 putative hydrolase K01451 hipO; hippurate hydrolase [EC:3.5.1.32]
C PAM18_4434 putative hydrolase K01451 hipO; hippurate hydrolase [EC:3.5.1.32]
B Family M23
C PAM18_3170 lasA; LasA protease precursor K08642 lasA; LasA protease [EC:3.4.24.-]
C PAM18_5679 hypothetical protein K21472 lytH; peptidoglycan LD-endopeptidase LytH [EC:3.4.-.-]
B Family M24
C PAM18_2223 putative methionine aminopeptidase K01265 map; methionyl aminopeptidase [EC:3.4.11.18]
C PAM18_1289 map; methionine aminopeptidase K01265 map; methionyl aminopeptidase [EC:3.4.11.18]
C PAM18_4589 putative metallopeptidase K01271 pepQ; Xaa-Pro dipeptidase [EC:3.4.13.9]
C PAM18_5342 pepP; aminopeptidase P K01262 pepP; Xaa-Pro aminopeptidase [EC:3.4.11.9]
B Family M26
B Family M27
B Family M28: aminopeptidase Y family
B Family M29: aminopeptidase T family
B Family M32: carboxypeptidase Taq family
B Family M34: anthrax lethal factor family
B Family M35: deuterolysin family
B Family M36: fungalysin family
B Family M38: beta-aspartyl dipeptidase family
B Family M41: FtsH endopeptidase family
C PAM18_4859 ftsH; cell division protein FtsH K03798 ftsH; cell division protease FtsH [EC:3.4.24.-]
B Family M42: glutamyl aminopeptidase family
B Family M43: cytophagalysin family
B Family M44
B Family M48: Ste24 endopeptidase family
C PAM18_2133 htpX; heat shock protein HtpX K03799 htpX; heat shock protein HtpX [EC:3.4.24.-]
C PAM18_0272 putative Zn-dependent protease with chaperone function K07387 K07387; metalloprotease [EC:3.4.24.-]
C PAM18_4043 Putative Zn-dependent protease K01423 bepA; beta-barrel assembly-enhancing protease [EC:3.4.-.-]
B Family M49: dipeptidyl-peptidase III family
B Family M50: S2P protease family
C PAM18_1297 putative membrane-associated zinc metalloprotease K11749 rseP; regulator of sigma E protease [EC:3.4.24.-]
B Family M54
B Family M55: DppA aminopeptidase family
B Family M56
B Family M67
B Family M72
B Family M73
B Family M74
B Family M80
B Family M82
B Family M85
B Family M88
C PAM18_0572 hypothetical protein K21429 impA; immunomodulating metalloprotease
B Family M90
C PAM18_0910 hypothetical protein K09933 mtfA; MtfA peptidase
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AAsparagine peptide lyases
B Family N1
B Family N8
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AMixed peptidases
B Family P1: DmpA aminopeptidase family
C PAM18_3645 putative D-aminopeptidase K01266 dmpA; D-aminopeptidase [EC:3.4.11.19]
B Family P2
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ASerine peptidases
B Family S1: chymotrypsin family
C PAM18_4272 mucD; serine protease MucD precursor K04771 degP; serine protease Do [EC:3.4.21.107]
C PAM18_4537 algW; AlgW protein K04691 hhoB; serine protease DegS [EC:3.4.21.-]
C PAM18_0762 piv; protease IV K01337 E3.4.21.50; lysyl endopeptidase [EC:3.4.21.50]
B Family S3: togavirin family
B Family S6
B Family S7: flavivirin family
B Family S8: subtilisin family
B Family S9: prolyl oligopeptidase family
C PAM18_3599 putative oligopeptidase K01354 ptrB; oligopeptidase B [EC:3.4.21.83]
B Family S10
B Family S11: D-Ala-D-Ala carboxypeptidase A family
C PAM18_0941 dacC; D-ala-D-ala-carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4]
C PAM18_4170 pbpG; D-alanyl-D-alanine endopeptidase K07262 pbpG; serine-type D-Ala-D-Ala endopeptidase (penicillin-binding protein 7) [EC:3.4.21.-]
B Family S12: D-Ala-D-Ala carboxypeptidase B family
B Family S13: D-Ala-D-Ala peptidase C family
C PAM18_1913 putative D-alanyl-D-alanine carboxypeptidase K07259 dacB; serine-type D-Ala-D-Ala carboxypeptidase/endopeptidase (penicillin-binding protein 4) [EC:3.4.16.4 3.4.21.-]
B Family S14: ClpP endopeptidase family
C PAM18_1639 ATP-dependent Clp protease proteolytic subunit K01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92]
C PAM18_3243 clpP; ATP-dependent Clp protease proteolytic subunit K01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92]
B Family S15
B Family S16: lon protease family
C PAM18_4259 putative ATP-dependent protease K01338 lon; ATP-dependent Lon protease [EC:3.4.21.53]
C PAM18_3241 lon; Lon protease K01338 lon; ATP-dependent Lon protease [EC:3.4.21.53]
B Family S21: assemblin family
B Family S24: LexA family
C PAM18_1953 lexA; LexA repressor K01356 lexA; repressor LexA [EC:3.4.21.88]
B Family S26: signal peptidase I family
C PAM18_4270 lepB; signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89]
C PAM18_3600 putative signal peptidase K03100 lepB; signal peptidase I [EC:3.4.21.89]
B Family S28
B Family S31
B Family S32
B Family S33
C PAM18_5195 prolyl aminopeptidase K01259 pip; proline iminopeptidase [EC:3.4.11.5]
B Family S41: C-terminal processing peptidase family
C PAM18_1714 prc; periplasmic tail-specific protease K03797 E3.4.21.102; carboxyl-terminal processing protease [EC:3.4.21.102]
C PAM18_5248 putative carboxyl-terminal protease K03797 E3.4.21.102; carboxyl-terminal processing protease [EC:3.4.21.102]
B Family S45
C PAM18_3149 putative penicillin acylase K01434 pac; penicillin G amidase [EC:3.5.1.11]
C PAM18_0300 putative penicillin amidase K01434 pac; penicillin G amidase [EC:3.5.1.11]
B Family S49: protease IV family
C PAM18_1988 putative peptidase K04773 sppA; protease IV [EC:3.4.21.-]
C PAM18_3212 putative periplasmic protease K04774 sohB; serine protease SohB [EC:3.4.21.-]
B Family S50
B Family S51
B Family S53
B Family S54: Rhomboid family
C PAM18_1877 hypothetical protein K02441 glpG; rhomboid protease GlpG [EC:3.4.21.105]
B Family S55: SpoIVB peptidase family
B Family S62
B Family S66
C PAM18_5317 LD-carboxypeptidase K01297 ldcA; muramoyltetrapeptide carboxypeptidase [EC:3.4.17.13]
B Family S77: phage prohead processing peptidase family
B Family S78
C PAM18_1349 Phage head maturation protease K06904 GP4; Escherichia/Staphylococcus phage prohead protease
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AThreonine peptidases
B Family T1: proteasome family
C PAM18_5168 hslV; ATP-dependent protease peptidase subunit K01419 hslV; ATP-dependent HslUV protease, peptidase subunit HslV [EC:3.4.25.2]
B Family T2
B Family T3: gamma-glutamyltransferase family
C PAM18_0164 putative gamma-glutamyltranspeptidase K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
C PAM18_0359 putative gamma-glutamyltranspeptidase precursor K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
C PAM18_3564 ggt; gamma-glutamyltranspeptidase precursor K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
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APeptidases of unknown catalytic type
B Family U32
C PAM18_5561 putative peptidase K08303 prtC; U32 family peptidase [EC:3.4.-.-]
C PAM18_1028 putative peptidase K24845 ubiV; O2-independent ubiquinone biosynthesis protein UbiV
C PAM18_1027 putative protease K24844 ubiU; O2-independent ubiquinone biosynthesis protein UbiU
B Family U62
C PAM18_4563 pmbA; PmbA protein K03592 pmbA; PmbA protein
C PAM18_4565 putative tldD protein K03568 tldD; TldD protein
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APeptidase inhibitors
B Family I1: Kazal family
B Family I2: Kunitz - BPTI family
B Family I4: serpin family
B Family I11: ecotin family
C PAM18_2210 eco; ecotin K08276 eco; ecotin
B Family I17: WAP-type family
B Family I25: cystatin family
B Family I27: calpastatin family
B Family I32: IAP family
B Family I34: IA3 family
B Family I35: timp family
B Family I39: alpha2M family
C PAM18_4580 hypothetical protein K06894 yfhM; alpha-2-macroglobulin
B Family I47: latexin family
B Family I49: proSAAS family
B Family I51: IC family
B Family I57: staphostatin B family
B Family I63
B Family I80
B Family I87
C PAM18_2595 hypothetical protein K04087 hflC; modulator of FtsH protease HflC
C PAM18_5052 hflC; protease subunit HflC K04087 hflC; modulator of FtsH protease HflC
C PAM18_5053 hflK; protease subunit HflK K04088 hflK; modulator of FtsH protease HflK
B Family I93
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: December 13, 2023
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Classification taken and modified from MEROPS