+F Repair protein KO
#
DNA Repair and Recombination Proteins - Pseudomonas aeruginosa UCBPP-PA14
%
!
AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D PA14_51440 ogt; methylated-DNA-protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D PA14_61640 phr; deoxyribodipyrimidine photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E PA14_54590 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E PA14_11970 methylpurine-DNA glycosylase family protein K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E PA14_67990 mutY; A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E PA14_18880 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
E PA14_40350 putative DNA helicase K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D PA14_57190 mutT; putative pyrophosphohydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D PA14_23100 mutT; putative 7,8-dihydro-8-oxoguanine-triphosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D PA14_28290 putative pyrophosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D PA14_19205 hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D PA14_64930 putative ADP-ribose pyrophosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D PA14_70260 dut; deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
#
AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D PA14_51440 ogt; methylated-DNA-protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D PA14_17760 ada; putative methylated-DNA--protein-cysteine methyltransferase K10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response / methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]
D PA14_37190 ada; O6-methylguanine-DNA methyltransferase K10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response / methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]
D PA14_61640 phr; deoxyribodipyrimidine photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E PA14_54590 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E PA14_42700 alkA; DNA-3-methyladenine glycosidase II K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E PA14_11970 methylpurine-DNA glycosylase family protein K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E PA14_67990 mutY; A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E PA14_00110 tag; DNA-3-methyladenine glycosidase I K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E PA14_04670 mutM; formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E PA14_18880 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E PA14_70390 crc; catabolite repression control protein K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E PA14_31650 xthA; exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E PA14_09930 putative exonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D RecJ
E PA14_16220 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E PA14_44660 lig; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E PA14_72490 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E PA14_09180 uvrA; excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
E PA14_23510 uvrB; excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
E PA14_30660 uvrC; excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C
E PA14_71870 uvrD; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E PA14_60080 conserved hypothetical protein K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E PA14_72490 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E PA14_44660 lig; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F PA14_08760 rpoB; DNA-directed RNA polymerase beta chain K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F PA14_08780 rpoC; DNA-directed RNA polymerase beta* chain K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F PA14_09115 rpoA; DNA-directed RNA polymerase alpha chain K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F PA14_70450 rpoZ; RNA polymerase omega subunit K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F PA14_25230 mfd; transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E PA14_17500 mutS; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
D Molecular matchmaker
E PA14_65350 mutL; DNA mismatch repair protein MutL K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
D DNA exonucleases
E PA14_56080 sbcB; exodeoxyribonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
E PA14_15230 xseA; exodeoxyribonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E PA14_55080 hypothetical protein K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E PA14_11570 xseB; exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E PA14_17260 dnaE; DNA polymerase III, alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E PA14_00020 dnaN; DNA polymerase III, beta chain K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E PA14_14460 holC; DNA polymerase holoenzyme chi subunit K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
E PA14_12200 holA; DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E PA14_25760 holB; DNA polymerase III, delta prime subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E PA14_41050 dnaQ; DNA polymerase III, epsilon chain K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E PA14_22380 putative nuclease K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E PA14_44630 dnaX; DNA polymerase subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E PA14_44660 lig; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E PA14_71870 uvrD; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E PA14_60080 conserved hypothetical protein K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E PA14_09200 ssb; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E PA14_59150 putative single-stranded DNA binding protein K03111 ssb; single-strand DNA-binding protein
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E PA14_55670 recB; exodeoxyribonuclease V beta chain K03582 recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5]
E PA14_55690 recC; exodeoxyribonuclease V gamma chain K03583 recC; exodeoxyribonuclease V gamma subunit [EC:3.1.11.5]
E PA14_55660 recD; exodeoxyribonuclease V alpha chain K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E PA14_17530 recA; RecA protein K03553 recA; recombination protein RecA
E PA14_51790 ruvA; Holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E PA14_51780 ruvB; Holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E PA14_51800 ruvC; Holliday junction resolvase RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E PA14_66720 priA; primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E PA14_28895 hypothetical protein K04067 priC; primosomal replication protein N''
E PA14_56080 sbcB; exodeoxyribonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
E PA14_55650 sbcC; putative exonuclease K03546 sbcC; DNA repair protein SbcC/Rad50
E PA14_55640 sbcD; exonuclease SbcD K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E PA14_17530 recA; RecA protein K03553 recA; recombination protein RecA
E PA14_60990 radA; DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
E PA14_00030 recF; DNA replication and repair protein RecF K03629 recF; DNA replication and repair protein RecF
E PA14_70570 recG; ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E PA14_16220 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E PA14_54300 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E PA14_44610 recR; recombination protein RecR K06187 recR; recombination protein RecR
E PA14_63010 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
E PA14_21790 rdgC; putative recombination associated protein RdgC K03554 rdgC; recombination associated protein RdgC
E PA14_51790 ruvA; Holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E PA14_51780 ruvB; Holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E PA14_51800 ruvC; Holliday junction resolvase RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
D Other HR factor
E PA14_33350 hypothetical protein K15342 cas1; CRISP-associated protein Cas1
D Archaeal homologous recombinant proteins
E PA14_55650 sbcC; putative exonuclease K03546 sbcC; DNA repair protein SbcC/Rad50
E PA14_55640 sbcD; exonuclease SbcD K03547 sbcD; DNA repair protein SbcD/Mre11
E PA14_55980 yjgR; conserved hypothetical protein K06915 herA; DNA double-strand break repair helicase HerA and related ATPase
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
E PA14_36760 putative KU domain protein K10979 ku; DNA end-binding protein Ku
E PA14_36910 putative ATP-dependent DNA ligase K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1]
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F PA14_23260 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F PA14_00050 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F PA14_59180 topoisomerase I - like protein K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
F PA14_25110 topA; DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
F PA14_35570 pslN; putative DNA topoisomerase K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F PA14_70600 hupA; putative DNA-binding protein HU family K05787 hupA; DNA-binding protein HU-alpha
F PA14_41210 hupB; DNA-binding protein HU K03530 hupB; DNA-binding protein HU-beta
F PA14_12900 histone-like protein HU form N K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F PA14_16220 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F PA14_54300 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F PA14_44610 recR; recombination protein RecR K06187 recR; recombination protein RecR
F PA14_44660 lig; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
F PA14_64190 fis; DNA-binding protein Fis K03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein
F PA14_28720 himA; integration host factor, alpha subunit K04764 ihfA; integration host factor subunit alpha
F PA14_23340 himD; integration host factor beta subunit K05788 ihfB; integration host factor subunit beta
E Supressor
F PA14_56080 sbcB; exodeoxyribonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
F PA14_20810 recQ; ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F PA14_28810 putative DNA helicase K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F PA14_09180 uvrA; excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
F PA14_23510 uvrB; excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D PA14_52310 dinP; DNA damage inducible protein P K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
C Other SOS response factors
D PA14_17530 recA; RecA protein K03553 recA; recombination protein RecA
D PA14_25160 lexA; repressor protein LexA K01356 lexA; repressor LexA [EC:3.4.21.88]
D PA14_63010 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D PA14_40120 polB; DNA polymerase II K02336 polB; DNA polymerase II [EC:2.7.7.7]
D PA14_55590 hypothetical protein K14160 imuA; protein ImuA
D PA14_55600 hypothetical protein K14161 imuB; protein ImuB
D PA14_55610 conserved hypothetical protein K14162 dnaE2; error-prone DNA polymerase [EC:2.7.7.7]
D PA14_09200 ssb; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D PA14_59150 putative single-stranded DNA binding protein K03111 ssb; single-strand DNA-binding protein
D PA14_17540 recX; putative recX protein K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D PA14_69910 rep; ATP-dependent DNA helicase Rep K03656 rep; ATP-dependent DNA helicase Rep [EC:5.6.2.4]
D PA14_50840 Putative DNA helicase K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
D PA14_21690 lhr1; putative ATP-dependent DNA helicase K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
D PA14_28840 putative helicase K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
C Modulation of nucleotide pools
D PA14_57190 mutT; putative pyrophosphohydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D PA14_23100 mutT; putative 7,8-dihydro-8-oxoguanine-triphosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D PA14_28290 putative pyrophosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D PA14_19205 hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D PA14_64930 putative ADP-ribose pyrophosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D PA14_70260 dut; deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D PA14_72540 putative ribonucleotide reductase K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D PA14_49460 nrdA; ribonucleoside reductase, large chain K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D PA14_49470 nrdB; ribonucleoside reductase, small chain K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
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#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024