+E Messenger RNA Biogenesis KO #

  Messenger RNA Biogenesis - Plasmodium falciparum 3D7

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AEukaryotic type B mRNA processing factors C 5' end processing D Capping factors E PF3D7_1356900 protein kinase 5 K04563 CDC28; cyclin-dependent kinase [EC:2.7.11.22] E PF3D7_1014400 MO15-related protein kinase K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23] E PF3D7_1414600 mRNA-capping enzyme subunit alpha K00987 CEG1; mRNA guanylyltransferase [EC:2.7.7.50] D Cap binding complex E PF3D7_0415500 nuclear cap-binding protein subunit 2, putative K12883 NCBP2; nuclear cap-binding protein subunit 2 C 3' end processing D Pre-mRNA cleavage factor Im (CFIm) E PF3D7_0109200 cleavage and polyadenylation specificity factor subunit 5, putative K14397 NUDT21; cleavage and polyadenylation specificity factor subunit 5 D Pre-mRNA cleavage factor IIm (CFIIm) E PF3D7_0821600 polyribonucleotide 5'-hydroxyl-kinase Clp1, putative K14399 CLP1; polyribonucleotide 5'-hydroxyl-kinase [EC:2.7.1.78] D Cleavage and polyadenylation specificity factor (CPSF) complex E PF3D7_1438500 cleavage and polyadenylation specificity factor subunit 3, putative K14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-] E PF3D7_1243800 uncharacterized protein K14962 WDR82; COMPASS component SWD2 E PF3D7_1414400 serine/threonine protein phosphatase PP1 K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16] D Cleavage stimulation factor (CSTF) complex E PF3D7_0620500 cleavage stimulation factor subunit 1, putative K14406 CSTF1; cleavage stimulation factor subunit 1 D U7-dependent histone pre-mRNA processing factors E PF3D7_1414800 small nuclear ribonucleoprotein-associated protein B, putative K11086 SNRPB; small nuclear ribonucleoprotein B and B' E PF3D7_0909800 small nuclear ribonucleoprotein Sm D3, putative K11088 SNRPD3; small nuclear ribonucleoprotein D3 E PF3D7_1350200 small nuclear ribonucleoprotein E, putative K11097 SNRPE; small nuclear ribonucleoprotein E E PF3D7_1126900 small nuclear ribonucleoprotein F, putative K11098 SNRPF; small nuclear ribonucleoprotein F E PF3D7_0822300 small nuclear ribonucleoprotein G, putative K11099 SNRPG; small nuclear ribonucleoprotein G E PF3D7_1438500 cleavage and polyadenylation specificity factor subunit 3, putative K14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-] E PF3D7_0519000 histone RNA hairpin-binding protein, putative K18710 SLBP; histone RNA hairpin-binding protein D DRB sensitivity inducing factor (DSIF) complex E PF3D7_1030000 transcription elongation factor SPT4, putative K15171 SUPT4H1; transcription elongation factor SPT4 E PF3D7_0610900 transcription elongation factor SPT5, putative K15172 SUPT5H; transcription elongation factor SPT5 D N6-methyltransferase complex E PF3D7_0729500 mRNA (N6-adenosine)-methyltransferase, putative K05925 METTL3; mRNA m6A methyltransferase catalytic subunit [EC:2.1.1.348] E PF3D7_1235500 mRNA methyltransferase, putative K23960 METTL14; mRNA m6A methyltransferase non-catalytic subunit E PF3D7_1230800 pre-mRNA-splicing regulator, putative K22824 WTAP; pre-mRNA-splicing regulator WTAP D Poly(A) addition factors E PF3D7_0625600 poly(A) polymerase PAP, putative K14376 PAP; poly(A) polymerase [EC:2.7.7.19] D Negative regulators of mRNA 3' end processing C Other processing factors D PF3D7_1467500 DNA/RNA-binding protein KIN17, putative K13102 KIN; DNA/RNA-binding protein KIN17 D PF3D7_0623100 nuclear polyadenylated RNA-binding protein NAB2, putative K23038 ZC3H14; zinc finger CCCH domain-containing protein 14 B mRNA surveillance and transport factors C Transport factors D EJC complex E PF3D7_1406000 RNA-binding protein 8A, putative K12876 RBM8A; RNA-binding protein 8A E PF3D7_0725200 mago nashi protein homologue, putative K12877 MAGOH; protein mago nashi E PF3D7_0615700 RNA and export factor binding protein, putative K12881 THOC4; THO complex subunit 4 E PF3D7_0209800 ATP-dependent RNA helicase UAP56 K12812 DDX39B; ATP-dependent RNA helicase UAP56/SUB2 [EC:5.6.2.7] E PF3D7_0422700 eukaryotic initiation factor 4A-III, putative K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7] D TREX complex E PF3D7_0615700 RNA and export factor binding protein, putative K12881 THOC4; THO complex subunit 4 D TREX-2 complex E PF3D7_0721800 conserved Plasmodium protein, unknown function K10881 SHFM1; 26 proteasome complex subunit DSS1 E PF3D7_1027700.1 centrin-3 K16466 CETN3; centrin-3 D Nuclear pore complex E PF3D7_1230700 protein transport protein SEC13 K14004 SEC13; protein transport protein SEC13 E PF3D7_1027700.1 centrin-3 K16466 CETN3; centrin-3 D Ran-mediated transport factors E PF3D7_1117700 GTP-binding nuclear protein RAN/TC4 K07936 RAN; GTP-binding nuclear protein Ran E PF3D7_1427900 leucine-rich repeat protein K18647 ANP32B; acidic leucine-rich nuclear phosphoprotein 32 family member B E PF3D7_0934700 UBX domain-containing protein, putative K18726 FAF2; FAS-associated factor 2 E PF3D7_0619400 cell division cycle protein 48 homologue, putative K13525 VCP; transitional endoplasmic reticulum ATPase E PF3D7_0302900 exportin-1, putative K14290 XPO1; exportin-1 E PF3D7_0910100 exportin-7, putative K18460 XPO7; exportin-7 D eIF4F and regulatory proteins E PF3D7_0315100 eukaryotic translation initiation factor 4E K03259 EIF4E; translation initiation factor 4E E PF3D7_1468700 eukaryotic initiation factor 4A K03257 EIF4A; translation initiation factor 4A E PF3D7_0810600 ATP-dependent RNA helicase DBP1, putative K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7] E PF3D7_1031500 DEAD/DEAH box helicase, putative K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7] E PF3D7_1224300 polyadenylate-binding protein 1, putative K13126 PABPC; polyadenylate-binding protein E PF3D7_0529500 cell cycle regulator protein, putative K07575 MCTS; malignant T-cell-amplified sequence E PF3D7_0813600 translation initiation factor SUI1, putative K24272 DENR; density-regulated protein D APOBEC1-ACF complex D Other transport factors E PF3D7_1209000 mago-binding protein, putative K14294 WIBG; partner of Y14 and mago E PF3D7_0414500 RNA-binding protein, putative K14411 MSI; RNA-binding protein Musashi E PF3D7_0722100 protein pelota homolog, putative K06965 PELO; protein pelota E PF3D7_0923900 polyadenylate-binding protein 2, putative K14396 PABPN1; polyadenylate-binding protein 2 E PF3D7_1459000 ATP-dependent RNA helicase DBP5 K18655 DDX19; ATP-dependent RNA helicase DDX19/DBP5 [EC:5.6.2.7] E PF3D7_1235900 pre-mRNA-splicing factor SYF1, putative K12867 SYF1; pre-mRNA-splicing factor SYF1 E PF3D7_0912500 SAP domain-containing protein, putative K18732 SARNP; SAP domain-containing ribonucleoprotein E PF3D7_0711500 regulator of chromosome condensation, putative K11493 RCC1; regulator of chromosome condensation C Surveillance factors D Surveillance complex E PF3D7_0212300 peptide chain release factor subunit 1, putative K03265 ETF1; peptide chain release factor subunit 1 E PF3D7_1123400 translation elongation factor EF-1, subunit alpha, putative K03267 ERF3; peptide chain release factor subunit 3 E PF3D7_1005500 regulator of nonsense transcripts 1, putative K14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3] E PF3D7_0925800 armadillo repeat protein, putative K14327 UPF2; regulator of nonsense transcripts 2 D Protein phosphatase 2A E PF3D7_0925400 protein phosphatase-beta K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16] E PF3D7_1356400 phosphatase 2A regulatory subunit-related protein, putative K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B'' D Other surveillance factors E PF3D7_0309700 SECIS-binding protein 2, putative K19539 SECISBP2; selenocysteine insertion sequence-binding protein 2 C Factors involved in mRNA localization D Cargo complex E PF3D7_0621300 mRNA-binding protein PUF3 K14844 PUF6; pumilio homology domain family member 6 E PF3D7_0204800 3'-5' exonuclease, putative K18740 EXD1; exonuclease 3'-5' domain-containing protein 1 D Factors that have mRNA localization signals D Trans-acting binding proteins E PF3D7_1357000 elongation factor 1-alpha K03231 EEF1A; elongation factor 1-alpha E PF3D7_1357100 elongation factor 1-alpha K03231 EEF1A; elongation factor 1-alpha E PF3D7_1338300 elongation factor 1-gamma, putative K03233 EEF1G; elongation factor 1-gamma D Other mRNA localization factors C mRNA cycle factors D Common to processing body (P body) and stress granule E PF3D7_1106300 exonuclease, putative K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-] E PF3D7_0315100 eukaryotic translation initiation factor 4E K03259 EIF4E; translation initiation factor 4E E PF3D7_1005500 regulator of nonsense transcripts 1, putative K14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3] E PF3D7_0810600 ATP-dependent RNA helicase DBP1, putative K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7] E PF3D7_1031500 DEAD/DEAH box helicase, putative K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7] E PF3D7_0320800 ATP-dependent RNA helicase DDX6 K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7] E PF3D7_1474900 trailer hitch homolog, putative K18749 LSM14; protein LSM14 E PF3D7_0627700 transportin K18752 TNPO1; transportin-1 E PF3D7_0934800 cAMP-dependent protein kinase catalytic subunit K04345 PKA; protein kinase A [EC:2.7.11.11] D P-body specific factors E PF3D7_1308900 mRNA-decapping enzyme 2, putative K12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62] E PF3D7_1124400 U6 snRNA-associated Sm-like protein LSm1, putative K12620 LSM1; U6 snRNA-associated Sm-like protein LSm1 E PF3D7_0520300 U6 snRNA-associated Sm-like protein LSm2, putative K12621 LSM2; U6 snRNA-associated Sm-like protein LSm2 E PF3D7_0819900 U6 snRNA-associated Sm-like protein LSm3, putative K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3 E PF3D7_1107000 U6 snRNA-associated Sm-like protein LSm4, putative K12623 LSM4; U6 snRNA-associated Sm-like protein LSm4 E PF3D7_1443300 U6 snRNA-associated Sm-like protein LSm5, putative K12624 LSM5; U6 snRNA-associated Sm-like protein LSm5 E PF3D7_1325000 U6 snRNA-associated Sm-like protein LSm6, putative K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6 E PF3D7_1209200 U6 snRNA-associated Sm-like protein LSm7, putative K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7 E PF3D7_0829300 U6 snRNA-associated Sm-like protein LSm8, putative K12627 LSM8; U6 snRNA-associated Sm-like protein LSm8 E PF3D7_0422300 alpha tubulin 2 K07374 TUBA; tubulin alpha E PF3D7_0903700 alpha tubulin 1 K07374 TUBA; tubulin alpha E PF3D7_1103800 CCR4-NOT transcription complex subunit 1, putative K12604 CNOT1; CCR4-NOT transcription complex subunit 1 E PF3D7_1128600 CCR4-NOT transcription complex subunit 2, putative K12605 CNOT2; CCR4-NOT transcription complex subunit 2 E PF3D7_0519500 CCR4 domain-containing protein 1, putative K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4] E PF3D7_0811300 CCR4-associated factor 1 K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8 E PF3D7_0925800 armadillo repeat protein, putative K14327 UPF2; regulator of nonsense transcripts 2 E PF3D7_1027400 DNA-directed RNA polymerase II subunit RPB7, putative K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7 D Stress granule specific factors E PF3D7_1224300 polyadenylate-binding protein 1, putative K13126 PABPC; polyadenylate-binding protein E PF3D7_1438000 eukaryotic translation initiation factor eIF2A, putative K15026 EIF2A; translation initiation factor 2A E PF3D7_0517700 eukaryotic translation initiation factor 3 subunit B, putative K03253 EIF3B; translation initiation factor 3 subunit B E PF3D7_1468700 eukaryotic initiation factor 4A K03257 EIF4A; translation initiation factor 4A E PF3D7_0422700 eukaryotic initiation factor 4A-III, putative K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7] E PF3D7_0826700 receptor for activated c kinase K14753 RACK1; guanine nucleotide-binding protein subunit beta-2-like 1 protein B mRNA degradation factors C 5'-3' decay D Decapping complex E PF3D7_1308900 mRNA-decapping enzyme 2, putative K12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62] E PF3D7_0320800 ATP-dependent RNA helicase DDX6 K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7] D Lsm complex E PF3D7_1124400 U6 snRNA-associated Sm-like protein LSm1, putative K12620 LSM1; U6 snRNA-associated Sm-like protein LSm1 E PF3D7_0520300 U6 snRNA-associated Sm-like protein LSm2, putative K12621 LSM2; U6 snRNA-associated Sm-like protein LSm2 E PF3D7_0819900 U6 snRNA-associated Sm-like protein LSm3, putative K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3 E PF3D7_1107000 U6 snRNA-associated Sm-like protein LSm4, putative K12623 LSM4; U6 snRNA-associated Sm-like protein LSm4 E PF3D7_1443300 U6 snRNA-associated Sm-like protein LSm5, putative K12624 LSM5; U6 snRNA-associated Sm-like protein LSm5 E PF3D7_1325000 U6 snRNA-associated Sm-like protein LSm6, putative K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6 E PF3D7_1209200 U6 snRNA-associated Sm-like protein LSm7, putative K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7 E PF3D7_0829300 U6 snRNA-associated Sm-like protein LSm8, putative K12627 LSM8; U6 snRNA-associated Sm-like protein LSm8 D 5' exonucleases E PF3D7_1106300 exonuclease, putative K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-] E PF3D7_0909400 exoribonuclease, putative K12619 XRN2; 5'-3' exoribonuclease 2 [EC:3.1.13.-] D Other 5'-3' decay factors C 3'-5' decay D Core exosome factors E PF3D7_0720000 exosome complex component CSL4, putative K07573 CSL4; exosome complex component CSL4 E PF3D7_0410400 exosome complex component RRP4 K03679 RRP4; exosome complex component RRP4 E PF3D7_1307000 exosome complex component RRP40, putative K03681 RRP40; exosome complex component RRP40 E PF3D7_1427800 exosome complex component RRP41 K11600 RRP41; exosome complex component RRP41 E PF3D7_1340100 exosome complex component RRP42, putative K12589 RRP42; exosome complex component RRP42 E PF3D7_1364500 exosome complex component RRP45, putative K03678 RRP45; exosome complex component RRP45 D Exosome cofactors E PF3D7_1359300 exosome complex exonuclease RRP44 K12585 DIS3; exosome complex exonuclease DIS3/RRP44 [EC:3.1.13.-] E PF3D7_1445500 conserved Plasmodium protein, unknown function K12592 C1D; exosome complex protein LRP1 E PF3D7_0903400 ATP-dependent RNA helicase DDX60, putative K20103 DDX60; ATP-dependent RNA helicase DDX60 [EC:5.6.2.7] D TRAMP complex E PF3D7_1332400 nucleotidyltransferase, putative K03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19] E PF3D7_0602100 ATP-dependent RNA helicase, putative K12598 MTR4; ATP-dependent RNA helicase DOB1 [EC:5.6.2.6] D Ski complex D Ccr4-NOT complex E PF3D7_0519500 CCR4 domain-containing protein 1, putative K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4] E PF3D7_1103800 CCR4-NOT transcription complex subunit 1, putative K12604 CNOT1; CCR4-NOT transcription complex subunit 1 E PF3D7_1128600 CCR4-NOT transcription complex subunit 2, putative K12605 CNOT2; CCR4-NOT transcription complex subunit 2 E PF3D7_0811300 CCR4-associated factor 1 K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8 E PF3D7_0507600 protein CAF40, putative K12606 RCD1; CCR4-NOT transcription complex subunit 9 E PF3D7_1434000 CCR4-associated factor 16, putative K12608 CAF16; CCR4-NOT complex subunit CAF16 D Pan complex D Other 3'-5' decay factors E PF3D7_1443500 poly(A)-specific ribonuclease PARN, putative K01148 PARN; poly(A)-specific ribonuclease [EC:3.1.13.4] E PF3D7_0821300 ATP-dependent RNA helicase DHX36, putative K14442 DHX36; ATP-dependent RNA helicase DHX36 [EC:5.6.2.6] C Other degradation factors D RNases # AProkaryotic type B Bacterial mRNA degradation factors C RNA degradosome components D Ribonucreases D Helicases D Other RNA degradosome components E PF3D7_1015900 enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] C Other RNA degradation factors D Chaperones E PF3D7_1134000 heat shock protein 70 K04043 dnaK; molecular chaperone DnaK E PF3D7_1015600 heat shock protein 60 K04077 groEL; chaperonin GroEL [EC:5.6.1.7] E PF3D7_1232100 60 kDa chaperonin K04077 groEL; chaperonin GroEL [EC:5.6.1.7] D Others D Bacterial Small RNA Regulators B Archeal mRNA degradation factors C Exosome components D Core exosome E PF3D7_0410400 exosome complex component RRP4 K03679 RRP4; exosome complex component RRP4 E PF3D7_0720000 exosome complex component CSL4, putative K07573 CSL4; exosome complex component CSL4 D Cofactors E PF3D7_1427800 exosome complex component RRP41 K11600 RRP41; exosome complex component RRP41 E PF3D7_1340100 exosome complex component RRP42, putative K12589 RRP42; exosome complex component RRP42 D Others ! #
#[ BRITE | KEGG2 | KEGG ]
#Last updated: April 25, 2024