+E Replication protein KO
#
DNA Replication Proteins - Pangasianodon hypophthalmus (striped catfish)
%
!
AEukaryotic type
B DNA Replication Initiation Factors
C pre-RC (pre-replication complex)
D 113538196 orc1; origin recognition complex subunit 1 isoform X1 K02603 ORC1; origin recognition complex subunit 1
D 113536713 orc2; origin recognition complex subunit 2 K02604 ORC2; origin recognition complex subunit 2
D 113539004 orc3; origin recognition complex subunit 3 isoform X1 K02605 ORC3; origin recognition complex subunit 3
D 113538181 orc4; origin recognition complex subunit 4 K02606 ORC4; origin recognition complex subunit 4
D 113523881 orc5; LOW QUALITY PROTEIN: origin recognition complex subunit 5 K02607 ORC5; origin recognition complex subunit 5
D 113540975 orc6; origin recognition complex subunit 6 K02608 ORC6; origin recognition complex subunit 6
D 113546741 cdt1; DNA replication factor Cdt1 isoform X1 K10727 CDT1; chromatin licensing and DNA replication factor 1
D 113523649 cdc6; cell division control protein 6 homolog K02213 CDC6; cell division control protein 6
D 113538074 mcm2; DNA replication licensing factor MCM2 K02540 MCM2; DNA replication licensing factor MCM2 [EC:5.6.2.3]
D 113545359 maternal DNA replication licensing factor mcm3-like K02541 MCM3; DNA replication licensing factor MCM3 [EC:5.6.2.3]
D 113546781 zygotic DNA replication licensing factor mcm3-like K02541 MCM3; DNA replication licensing factor MCM3 [EC:5.6.2.3]
D 113533801 mcm4; DNA replication licensing factor MCM4 K02212 MCM4; DNA replication licensing factor MCM4 [EC:5.6.2.3]
D 113528247 mcm5; DNA replication licensing factor MCM5 K02209 MCM5; DNA replication licensing factor MCM5 [EC:5.6.2.3]
D 113546349 maternal DNA replication licensing factor mcm6-like K02542 MCM6; DNA replication licensing factor MCM6 [EC:5.6.2.3]
D 113538152 DNA replication licensing factor MCM6-like K02542 MCM6; DNA replication licensing factor MCM6 [EC:5.6.2.3]
D 113528420 mcm7; DNA replication licensing factor MCM7 K02210 MCM7; DNA replication licensing factor MCM7 [EC:5.6.2.3]
C CDK (cyclin dependent kinase)
D 113542701 ccna2; cyclin-A2 K06627 CCNA; cyclin-A
D 113543585 ccna1; cyclin-A1 K06627 CCNA; cyclin-A
D 113536206 G1/S-specific cyclin-E2-like isoform X1 K06626 CCNE; G1/S-specific cyclin-E1
D 113525127 ccne1; G1/S-specific cyclin-E1 K06626 CCNE; G1/S-specific cyclin-E1
D 113526749 G1/S-specific cyclin-E2-like K06626 CCNE; G1/S-specific cyclin-E1
D 113537787 cdk2; cyclin-dependent kinase 2 K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
C DDK (Dbf-4 dependent kinase)
D 113546440 cdc7; cell division cycle 7-related protein kinase K02214 CDC7; cell division control protein 7 [EC:2.7.11.1]
D 113532997 dbf4; protein DBF4 homolog A isoform X1 K06629 DBF4; protein DBF4
D 113535266 protein DBF4 homolog A-like K06629 DBF4; protein DBF4
C GINS complex
D 113542537 gins1; DNA replication complex GINS protein PSF1 isoform X1 K10732 GINS1; GINS complex subunit 1
D 113526917 gins2; DNA replication complex GINS protein PSF2 isoform X1 K10733 GINS2; GINS complex subunit 2
D 113546566 gins3; DNA replication complex GINS protein PSF3 K10734 GINS3; GINS complex subunit 3
D 113546046 gins4; DNA replication complex GINS protein SLD5 K10735 GINS4; GINS complex subunit 4
C Other initiation factors
D 113541131 topbp1; DNA topoisomerase 2-binding protein 1 isoform X1 K10728 TOPBP1; topoisomerase (DNA) II binding protein 1
D 113535887 recql4; ATP-dependent DNA helicase Q4 K10730 RECQL4; ATP-dependent DNA helicase Q4 [EC:5.6.2.4]
D 113524471 cdc45; cell division control protein 45 homolog K06628 CDC45; cell division control protein 45
D 113538879 mcm8; DNA helicase MCM8 isoform X1 K10737 MCM8; DNA helicase MCM8 [EC:5.6.2.4]
D 113531743 mcm9; DNA helicase MCM9 K10738 MCM9; DNA helicase MCM9 [EC:5.6.2.4]
D 113532424 mcm10; protein MCM10 homolog isoform X1 K10736 MCM10; minichromosome maintenance protein 10
D 113532329 helb; DNA helicase B K15254 HELB; DNA helicase B [EC:5.6.2.3]
D 113525542 protein FAM111A-like K24274 FAM111A; protein FAM111A
D 113538867 cinp; cyclin-dependent kinase 2-interacting protein isoform X1 K26052 CINP; cyclin-dependent kinase 2-interacting protein
D 113542236 mtbp; mdm2-binding protein isoform X1 K26116 MTBP; Mdm2-binding protein
D 113530131 ticrr; treslin K26117 TICRR; Treslin
B DNA Replication Elongation Factors
C DNA polymerase alpha / primase complex
D 113541094 pola1; DNA polymerase alpha catalytic subunit K02320 POLA1; DNA polymerase alpha subunit A [EC:2.7.7.7]
D 113535070 pola2; DNA polymerase alpha subunit B K02321 POLA2; DNA polymerase alpha subunit B
D 113530667 prim1; DNA primase small subunit K02684 PRI1; DNA primase small subunit [EC:2.7.7.102]
D 113545703 DNA primase large subunit-like K02685 PRI2; DNA primase large subunit
C DNA polymerase epsilon complex
D 113537200 pole; DNA polymerase epsilon catalytic subunit A K02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
D 113529713 pole2; DNA polymerase epsilon subunit 2 K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
D 113531087 pole3; DNA polymerase epsilon subunit 3 K02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
D 113533420 pole4; DNA polymerase epsilon subunit 4 K03506 POLE4; DNA polymerase epsilon subunit 4 [EC:2.7.7.7]
C DNA polymerase delta complex
D 113527875 pold1; DNA polymerase delta catalytic subunit K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
D 113546077 pold2; DNA polymerase delta subunit 2 K02328 POLD2; DNA polymerase delta subunit 2
D 113541476 pold3; DNA polymerase delta subunit 3 isoform X1 K03504 POLD3; DNA polymerase delta subunit 3
D 113539511 pold4; DNA polymerase delta subunit 4 K03505 POLD4; DNA polymerase delta subunit 4
C DNA polymerase gamma complex (mitochondrial)
D 113529834 polg; DNA polymerase subunit gamma-1 K02332 POLG; DNA polymerase gamma 1 [EC:2.7.7.7]
D 113538155 polg2; DNA polymerase subunit gamma-2, mitochondrial K02333 POLG2; DNA polymerase gamma 2
C RPA (replication protein A)
D 113532904 rpa1; replication protein A 70 kDa DNA-binding subunit K07466 RFA1; replication factor A1
D 113534072 rpa2; replication protein A 32 kDa subunit K10739 RFA2; replication factor A2
D 113543857 replication protein A 32 kDa subunit-A-like isoform X1 K10739 RFA2; replication factor A2
D 113543840 rpa3; replication protein A 14 kDa subunit K10740 RPA3; replication factor A3
C RFC (replication factor C)
D 113544373 rfc1; replication factor C subunit 1 K10754 RFC1; replication factor C subunit 1
D 113541724 rfc2; replication factor C subunit 2 K10755 RFC2_4; replication factor C subunit 2/4
D 113536617 rfc4; replication factor C subunit 4 K10755 RFC2_4; replication factor C subunit 2/4
D 113543591 rfc3; replication factor C subunit 3 K10756 RFC3_5; replication factor C subunit 3/5
D 113536817 rfc5; replication factor C subunit 5 K10756 RFC3_5; replication factor C subunit 3/5
C RNase H
D 113532414 rnaseh1; ribonuclease H1 K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D 113537269 rnaseh2a; ribonuclease H2 subunit A isoform X1 K10743 RNASEH2A; ribonuclease H2 subunit A [EC:3.1.26.4]
D 113546988 rnaseh2b; ribonuclease H2 subunit B K10744 RNASEH2B; ribonuclease H2 subunit B
D 113529184 rnaseh2c; ribonuclease H2 subunit C isoform X1 K10745 RNASEH2C; ribonuclease H2 subunit C
C Other elongation factors
D 113543926 pcna; proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
D 113540250 dna2; DNA replication ATP-dependent helicase/nuclease DNA2 isoform X1 K10742 DNA2; DNA replication ATP-dependent helicase/nuclease Dna2 [EC:5.6.2.3 3.1.-.-]
D 113533754 fen1; flap endonuclease 1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D 113546351 probable flap endonuclease 1 homolog K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D 113547451 zranb3; DNA annealing helicase and endonuclease ZRANB3 K25861 ZRANB3; DNA annealing helicase and endonuclease ZRANB3 [EC:5.6.2.- 3.1.-.-]
D 113533395 lig1; DNA ligase 1 K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
D 113535973 ATPase family AAA domain-containing protein 5-like K26118 ATAD5; ATPase family AAA domain-containing protein 5
B DNA Replication Termination Factors
C DNA methylation enzymes
D 113536050 dnmt1; DNA (cytosine-5)-methyltransferase 1 K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D 113539015 DNA (cytosine-5)-methyltransferase 3A-like isoform X1 K17398 DNMT3A; DNA (cytosine-5)-methyltransferase 3A [EC:2.1.1.37]
D 113528792 dnmt3a; DNA (cytosine-5)-methyltransferase 3A K17398 DNMT3A; DNA (cytosine-5)-methyltransferase 3A [EC:2.1.1.37]
D 113530535 DNA (cytosine-5)-methyltransferase 3B-like isoform X1 K17399 DNMT3B; DNA (cytosine-5)-methyltransferase 3B [EC:2.1.1.37]
D 113530266 uncharacterized protein LOC113530266 isoform X1 K17399 DNMT3B; DNA (cytosine-5)-methyltransferase 3B [EC:2.1.1.37]
D 113530725 uncharacterized protein LOC113530725 isoform X1 K17399 DNMT3B; DNA (cytosine-5)-methyltransferase 3B [EC:2.1.1.37]
C Prevention of re-replication factors
D 113535926 gmnn; geminin K10749 GMNN; geminin
D 113544165 mcidas; multicilin K26119 MCIDAS; multicilin
D 113531034 ccnb1; G2/mitotic-specific cyclin-B1 isoform X1 K05868 CCNB1; G2/mitotic-specific cyclin-B1
D 113540823 ccnb2; G2/mitotic-specific cyclin-B2 isoform X1 K21770 CCNB2; G2/mitotic-specific cyclin-B2
D 113540442 G2/mitotic-specific cyclin-B3-like K21771 CCNB3; G2/mitotic-specific cyclin-B3
D 113541596 G2/mitotic-specific cyclin-B3-like K21771 CCNB3; G2/mitotic-specific cyclin-B3
D 113534242 cdk1; cyclin-dependent kinase 1 K02087 CDK1; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
C Telomere proteins
D Shelterin complex
E 113529813 pot1; protection of telomeres protein 1 isoform X1 K11109 POT1; protection of telomeres protein 1
E 113541046 terf1; telomeric repeat-binding factor 1 K11110 TERF1; telomeric repeat-binding factor 1
E 113531976 terf2; telomeric repeat-binding factor 2 K11111 TERF2; telomeric repeat-binding factor 2
E 113540323 uncharacterized protein LOC113540323 isoform X1 K11112 TINF2; TERF1-interacting nuclear factor 2
E 113537818 terf2ip; telomeric repeat-binding factor 2-interacting protein 1 K11113 TERF2IP; telomeric repeat-binding factor 2-interacting protein 1
E 113536471 acd; adrenocortical dysplasia protein homolog K11114 ACD; adrenocortical dysplasia protein
D TERB1-TERB2-MAJIN complex
E 113526342 terb1; telomere repeats-binding bouquet formation protein 1 K25749 TERB1; telomere repeats-binding bouquet formation protein 1
E 113540985 terb2; telomere repeats-binding bouquet formation protein 2 isoform X1 K25750 TERB2; telomere repeats-binding bouquet formation protein 2
E 113539980 majin; membrane-anchored junction protein K25751 MAJIN; membrane-anchored junction protein
D CST complex (animals)
E 113525830 ctc1; CST complex subunit CTC1 K23311 CTC1; CST complex subunit CTC1
E 113537297 stn1; CST complex subunit STN1 K23312 STN1; CST complex subunit STN1
E 113538348 ten1; CST complex subunit TEN1 K23313 TEN1; CST complex subunit TEN1
D CST complex (yeast)
D RIF proteins
D SIR proteins
C Telomerase complex (animals)
D 113534882 smg6; telomerase-binding protein EST1A isoform X1 K11124 SMG6; protein SMG6 [EC:3.1.-.-]
D 113532861 smg5; LOW QUALITY PROTEIN: protein SMG5 K11125 SMG5; protein SMG5
D 113525259 tert; telomerase reverse transcriptase isoform X1 K11126 TERT; telomerase reverse transcriptase [EC:2.7.7.49]
D 113539125 tep1; telomerase protein component 1 K11127 TEP1; telomerase protein component 1
D Dyskerin complex
E 113547196 gar1; H/ACA ribonucleoprotein complex subunit 1 K11128 GAR1; H/ACA ribonucleoprotein complex subunit 1
E 113541640 nhp2; H/ACA ribonucleoprotein complex subunit 2 K11129 NHP2; H/ACA ribonucleoprotein complex subunit 2
E 113544395 nop10; H/ACA ribonucleoprotein complex subunit 3 K11130 NOP10; H/ACA ribonucleoprotein complex subunit 3
E 113541627 dkc1; H/ACA ribonucleoprotein complex subunit DKC1 isoform X1 K11131 DKC1; H/ACA ribonucleoprotein complex subunit 4 [EC:5.4.99.-]
C Telomerase complex (fungi)
D 113525259 tert; telomerase reverse transcriptase isoform X1 K11126 TERT; telomerase reverse transcriptase [EC:2.7.7.49]
D Sm core complex
E 113540458 snrpb; small nuclear ribonucleoprotein-associated proteins B and B' K11086 SNRPB; small nuclear ribonucleoprotein B and B'
E 113535923 snrpd1; small nuclear ribonucleoprotein Sm D1 K11087 SNRPD1; small nuclear ribonucleoprotein D1
E 113526387 snrpd2; small nuclear ribonucleoprotein Sm D2 K11096 SNRPD2; small nuclear ribonucleoprotein D2
E 113543198 snrpd3; small nuclear ribonucleoprotein Sm D3 K11088 SNRPD3; small nuclear ribonucleoprotein D3
E 113538002 snrpe; small nuclear ribonucleoprotein E K11097 SNRPE; small nuclear ribonucleoprotein E
E 113540432 snrpf; small nuclear ribonucleoprotein F K11098 SNRPF; small nuclear ribonucleoprotein F
E 113547096 snrpg; small nuclear ribonucleoprotein G K11099 SNRPG; small nuclear ribonucleoprotein G
C ELG1-RFC complex
D 113541724 rfc2; replication factor C subunit 2 K10755 RFC2_4; replication factor C subunit 2/4
D 113536617 rfc4; replication factor C subunit 4 K10755 RFC2_4; replication factor C subunit 2/4
D 113543591 rfc3; replication factor C subunit 3 K10756 RFC3_5; replication factor C subunit 3/5
D 113536817 rfc5; replication factor C subunit 5 K10756 RFC3_5; replication factor C subunit 3/5
C MRN complex
D 113543347 mre11; double-strand break repair protein MRE11 K10865 MRE11; double-strand break repair protein MRE11
D 113541563 rad50; DNA repair protein RAD50 isoform X1 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
D 113545466 nbn; nibrin K10867 NBN; nibrin
C Other termination factors
D 113543379 atm; serine-protein kinase ATM K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
D 113543536 wrn; Werner syndrome ATP-dependent helicase K10900 WRN; werner syndrome ATP-dependent helicase [EC:5.6.2.4]
D 113539553 blm; Bloom syndrome protein isoform X1 K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
D 113540485 prkdc; DNA-dependent protein kinase catalytic subunit isoform X1 K06642 PRKDC; DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1]
D 113527069 ercc4; DNA repair endonuclease XPF K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
D 113532176 parp1; poly [ADP-ribose] polymerase 1 K24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]
D 113535474 parp3; poly [ADP-ribose] polymerase 3 K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
D 113524149 parp4; poly [ADP-ribose] polymerase 4 isoform X1 K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
D 113539816 parp2; poly [ADP-ribose] polymerase 2 isoform X1 K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
D 113527434 tankyrase-2-like isoform X1 K10799 TNKS; tankyrase [EC:2.4.2.30]
D 113543110 tankyrase-1 isoform X1 K10799 TNKS; tankyrase [EC:2.4.2.30]
D 113528162 tankyrase-1-like K10799 TNKS; tankyrase [EC:2.4.2.30]
D 113545335 pinx1; PIN2/TERF1-interacting telomerase inhibitor 1 K11135 PINX1; Pin2-interacting protein X1
D 113532425 rtel1; regulator of telomere elongation helicase 1 K11136 RTEL1; regulator of telomere elongation helicase 1 [EC:5.6.2.3]
D 113547544 telo2; telomere length regulation protein TEL2 homolog K11137 TELO2; telomere length regulation protein
D 113534678 trir; telomerase RNA component interacting RNase K01149 TRIR; telomerase RNA component interacting RNase [EC:3.1.13.-]
D 113525144 rif1; telomere-associated protein RIF1 K11138 RIF1; telomere-associated protein RIF1
D 113546338 pif1; ATP-dependent DNA helicase PIF1 isoform X1 K15255 PIF1; ATP-dependent DNA helicase PIF1 [EC:5.6.2.3]
D 113528748 transcriptional activator protein Pur-alpha-like K21772 PURA; transcriptional activator protein Pur-alpha
D 113541609 pura; transcriptional activator protein Pur-alpha K21772 PURA; transcriptional activator protein Pur-alpha
D 113543537 purg; purine-rich element-binding protein gamma K21800 PURG; purine-rich element-binding protein gamma
D 113540675 wrap53; telomerase Cajal body protein 1 K23314 WRAP53; telomerase Cajal body protein 1
D 113547586 sde2; replication stress response regulator SDE2 K25059 SDE2; replication stress response regulator SDE2
D 113528331 rtf2; protein RTF2 homolog K25186 RTF2; replication termination factor 2
B DNA Topoisomerases
C 113545569 DNA topoisomerase 1-like K03163 TOP1; DNA topoisomerase I [EC:5.6.2.1]
C 113526372 DNA topoisomerase I, mitochondrial-like isoform X1 K03163 TOP1; DNA topoisomerase I [EC:5.6.2.1]
C 113534643 DNA topoisomerase I, mitochondrial-like isoform X1 K03163 TOP1; DNA topoisomerase I [EC:5.6.2.1]
C 113547493 DNA topoisomerase 2-alpha-like K03164 TOP2; DNA topoisomerase II [EC:5.6.2.2]
C 113543764 top2b; DNA topoisomerase 2-beta K03164 TOP2; DNA topoisomerase II [EC:5.6.2.2]
C 113536896 top3b; DNA topoisomerase 3-beta-1 K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
C 113536002 top3a; DNA topoisomerase 3-alpha K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
#
AProkaryotic type
B DNA Replication Initiation Factors
C Initiation factors (bacterial)
D 113531830 ssbp1; single-stranded DNA-binding protein, mitochondrial K03111 ssb; single-strand DNA-binding protein
C Initiation factors (archaeal)
B DNA Replication Elongation Factors
C Elongation factors (bacterial)
D DNA polymerase III holoenzyme
D RNase H
E 113532414 rnaseh1; ribonuclease H1 K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D Other elongation factors
C Elongation factors (archaeal)
D B-family DNA polymerases
D D-family DNA polymerases
D RNase H
E 113532414 rnaseh1; ribonuclease H1 K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D RFC (replication factor C)
D Other elongation factors
E 113540250 dna2; DNA replication ATP-dependent helicase/nuclease DNA2 isoform X1 K10742 DNA2; DNA replication ATP-dependent helicase/nuclease Dna2 [EC:5.6.2.3 3.1.-.-]
E 113533754 fen1; flap endonuclease 1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
E 113546351 probable flap endonuclease 1 homolog K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
E 113533395 lig1; DNA ligase 1 K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
B DNA Replication Termination Factors
C Terminus site-binding protein
C DNA methylation enzymes
C Prevention of re-replication factors
B DNA Topoisomerases
!
#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: November 2, 2022