+E	Messenger RNA Biogenesis	KO
#<h2><a href="/kegg/brite.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; Messenger RNA Biogenesis - Purpureocillium lilacinum</h2>
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A<b>Eukaryotic type</b>
B  mRNA processing factors
C    5' end processing
D      Capping factors
E        VFPFJ_02716 mRNA cap guanine-N7 methyltransferase	K00565 RNMT; mRNA (guanine-N7-)-methyltransferase [EC:2.1.1.56] 
E        VFPFJ_07754 serine/threonine-protein kinase	K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23] 
D      Cap binding complex
E        VFPFJ_07930 cap binding protein	K12882 NCBP1; nuclear cap-binding protein subunit 1 
E        VFPFJ_01229 nuclear cap binding protein subunit 2	K12883 NCBP2; nuclear cap-binding protein subunit 2 
C    3' end processing
D      Pre-mRNA cleavage factor Im (CFIm)
E        VFPFJ_05430 cleavage and polyadenylation specific factor 5	K14397 NUDT21; cleavage and polyadenylation specificity factor subunit 5 
D      Pre-mRNA cleavage factor IIm (CFIIm)
E        VFPFJ_01533 mRNA cleavage and polyadenylation factor IA/II complex	K14399 CLP1; polyribonucleotide 5'-hydroxyl-kinase [EC:2.7.1.78] 
E        VFPFJ_03777 mRNA cleavage factor complex component Pcf11	K14400 PCF11; pre-mRNA cleavage complex 2 protein Pcf11 
D      Cleavage and polyadenylation specificity factor (CPSF) complex
E        VFPFJ_10123 protein CFT1	K14401 CPSF1; cleavage and polyadenylation specificity factor subunit 1 
E        VFPFJ_01879 cleavage and polyadenylylation specificity factor	K14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2 
E        VFPFJ_07044 endoribonuclease ysh1	K14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-] 
E        VFPFJ_09015 mRNA 3'-end-processing protein yth-1	K14404 CPSF4; cleavage and polyadenylation specificity factor subunit 4 
E        VFPFJ_08859 Fip1 like protein	K14405 FIP1L1; pre-mRNA 3'-end-processing factor FIP1 
E        VFPFJ_09460 MPE1-like protein	K15541 MPE1; protein MPE1 
E        VFPFJ_05774 polyadenylation factor subunit 2	K15542 PFS2; polyadenylation factor subunit 2 
E        VFPFJ_06247 histone H3 methyltransferase complex and RNA cleavage factor II complex, subunit SWD2	K14962 WDR82; COMPASS component SWD2 
E        VFPFJ_05690 serine/threonine-protein phosphatase PP1	K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16] 
E        VFPFJ_09133 serine/threonine-protein phosphatase PP-Z	K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16] 
E        VFPFJ_09036 RNA polymerase II subunit A	K15544 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16] 
D      Cleavage stimulation factor (CSTF) complex
E        VFPFJ_05214 RNA recognition motif containing protein	K14407 CSTF2; cleavage stimulation factor subunit 2 
E        VFPFJ_01916 CFIA complex component Rna14	K14408 CSTF3; cleavage stimulation factor subunit 3 
E        VFPFJ_05177 mRNA cleavage and polyadenylation specificity factor complex subunit	K06100 SYMPK; symplekin 
D      U7-dependent histone pre-mRNA processing factors
E        VFPFJ_03564 small nuclear ribonucleoprotein	K11086 SNRPB; small nuclear ribonucleoprotein B and B' 
E        VFPFJ_08235 LSM domain-containing protein	K11088 SNRPD3; small nuclear ribonucleoprotein D3 
E        VFPFJ_04634 LSM domain-containing protein	K11097 SNRPE; small nuclear ribonucleoprotein E 
E        VFPFJ_08578 LSM domain-containing protein	K11098 SNRPF; small nuclear ribonucleoprotein F 
E        VFPFJ_09869 LSM domain-containing protein	K11099 SNRPG; small nuclear ribonucleoprotein G 
E        VFPFJ_01879 cleavage and polyadenylylation specificity factor	K14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2 
E        VFPFJ_07044 endoribonuclease ysh1	K14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-] 
E        VFPFJ_05214 RNA recognition motif containing protein	K14407 CSTF2; cleavage stimulation factor subunit 2 
E        VFPFJ_05177 mRNA cleavage and polyadenylation specificity factor complex subunit	K06100 SYMPK; symplekin 
D      DRB sensitivity inducing factor (DSIF) complex
E        VFPFJ_07776 transcriptional elongation protein Spt4	K15171 SUPT4H1; transcription elongation factor SPT4 
E        VFPFJ_07696 transcription initiation protein spt5	K15172 SUPT5H; transcription elongation factor SPT5 
D      N6-methyltransferase complex
E        VFPFJ_08810 S-adenosyl-L-methionine dependent methyltransferase, predicted	K11393 METTL16; U6 snRNA m6A methyltransferase [EC:2.1.1.346] 
D      Poly(A) addition factors
E        VFPFJ_06614 Poly(A) polymerase	K14376 PAP; poly(A) polymerase [EC:2.7.7.19] 
D      Negative regulators of mRNA 3' end processing
C    Other processing factors
D      VFPFJ_07775 zinc finger protein RTS2	K13102 KIN; DNA/RNA-binding protein KIN17 
D      VFPFJ_03538 arsenite resistance protein Ars2	K27103 SRRT; serrate RNA effector molecule 
D      VFPFJ_03309 nuclear polyadenylated rna-binding protein	K23039 NAB2; nuclear polyadenylated RNA-binding protein NAB2 
B  mRNA surveillance and transport factors
C    Transport factors
D      EJC complex
E        VFPFJ_10109 RNA recognition motif domain-containingprotein	K12876 RBM8A; RNA-binding protein 8A 
E        VFPFJ_03182 mago nashi protein	K12877 MAGOH; protein mago nashi 
E        VFPFJ_05362 RNA binding protein	K12881 THOC4; THO complex subunit 4 
E        VFPFJ_06763 RNA recognition domain-containing protein	K12881 THOC4; THO complex subunit 4 
E        VFPFJ_00506 ATP-dependent RNA helicase SUB2	K12812 DDX39B; ATP-dependent RNA helicase UAP56/SUB2 [EC:5.6.2.7] 
E        VFPFJ_08304 eukaryotic initiation factor 4A	K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7] 
E        VFPFJ_04066 hypothetical protein	K25178 CCDC174; coiled-coil domain-containing protein 174 
E        VFPFJ_03549 pwi domain mrna processing protein	K13171 SRRM1; serine/arginine repetitive matrix protein 1 
D      TREX complex
E        VFPFJ_01151 nuclear matrix protein	K12878 THOC1; THO complex subunit 1 
E        VFPFJ_01461 tho2 protein	K12879 THOC2; THO complex subunit 2 
E        VFPFJ_03301 tho complex subunit 3	K12880 THOC3; THO complex subunit 3 
E        VFPFJ_05362 RNA binding protein	K12881 THOC4; THO complex subunit 4 
E        VFPFJ_06763 RNA recognition domain-containing protein	K12881 THOC4; THO complex subunit 4 
E        VFPFJ_03583 THO complex, subunit 5	K13174 THOC5; THO complex subunit 5 
D      TREX-2 complex
E        VFPFJ_01005 PCI domain-containing protein	K23801 PCID2; nuclear mRNA export protein PCID2/THP1 
E        VFPFJ_02671 ef-hand 2	K16466 CETN3; centrin-3 
E        VFPFJ_07906 GANP/Nin1/mts3/eIF-3 p25 family protein	K23719 SAC3; nuclear mRNA export protein SAC3 
D      Nuclear pore complex
E        VFPFJ_04227 TPR/MLP1/MLP2-like protein	K09291 TPR; nucleoprotein TPR 
E        VFPFJ_04550 Poly(A)+ RNA export protein	K14298 RAE1; mRNA export factor 
E        VFPFJ_04088 protein transporter sec-13	K14004 SEC13; protein transport protein SEC13 
E        VFPFJ_06060 nuclear pore protein NUP57	K14308 NUP54; nuclear pore complex protein Nup54 
E        VFPFJ_05355 nucleoporin, NSP1-lik	K14306 NUP62; nuclear pore complex protein Nup62 
E        VFPFJ_07205 nuclear pore protein (Nic96)	K14309 NUP93; nuclear pore complex protein Nup93 
E        VFPFJ_02670 nucleoporin SONB	K14297 NUP98; nuclear pore complex protein Nup98-Nup96 
E        VFPFJ_03260 nuclear pore complex protein	K14301 NUP107; nuclear pore complex protein Nup107 
E        VFPFJ_08620 nuclear pore complex subunit	K14300 NUP133; nuclear pore complex protein Nup133 
E        VFPFJ_01289 nucleoporin	K14311 NUP188; nuclear pore complex protein Nup188 
E        VFPFJ_01475 non-repetitive nucleoporin	K14312 NUP155; nuclear pore complex protein Nup155 
E        VFPFJ_01261 nuclear pore complex subunit	K14310 NUP205; nuclear pore complex protein Nup205 
E        VFPFJ_08858 nucleoporin NUP49/NSP49	K14307 NUPL1; nucleoporin p58/p45 
E        VFPFJ_06716 nuclear envelope protein	K14315 NDC1; nucleoporin NDC1 
E        VFPFJ_06277 nuclear pore complex subunit	K14299 SEH1; nucleoporin SEH1 
E        VFPFJ_05218 nuclear pore complex subunit	K18715 NUP159; nucleoporin NUP159 
E        VFPFJ_02147 CCCH zinc finger domain-containingprotein	K18716 NUP42; nucleoporin NUP42 
E        VFPFJ_01228 nuclear pore complex protein An-Nup82	K18719 NUP82; nucleoporin NUP82 
E        VFPFJ_02671 ef-hand 2	K16466 CETN3; centrin-3 
E        VFPFJ_08041 RNA export mediator Gle1	K18723 GLE1; nucleoporin GLE1 
E        VFPFJ_05000 mRNA export factor mex67	K14284 NXF; nuclear RNA export factor 
E        VFPFJ_10821 nuclear transport factor 2, Eukaryote	K14285 NXT1_2; NTF2-related export protein 1/2 
E        VFPFJ_07920 nuclear pore complex component	K18724 POM34; nucleoporin POM34 
E        VFPFJ_02244 nuclear envelope pore membrane protein	K18725 POM152; nucleoporin POM152 
D      Ran-mediated transport factors
E        VFPFJ_03551 Ran GTPase	K07936 RAN; GTP-binding nuclear protein Ran 
E        VFPFJ_02937 UBX domain-containing protein	K18726 FAF2; FAS-associated factor 2 
E        VFPFJ_01272 cell division cycle protein 48	K13525 VCP; transitional endoplasmic reticulum ATPase 
E        VFPFJ_06804 exportin-1	K14290 XPO1; exportin-1 
E        VFPFJ_04978 ran GTPase-activating protein 1	K14319 RANGAP1; Ran GTPase-activating protein 1 
D      eIF4F and regulatory proteins
E        VFPFJ_07997 eukaryotic translation initiation factor 4E-4	K03259 EIF4E; translation initiation factor 4E 
E        VFPFJ_09994 translation Initiation Factor Eif4e	K03259 EIF4E; translation initiation factor 4E 
E        VFPFJ_05350 eukaryotic initiation factor 4A	K03257 EIF4A; translation initiation factor 4A 
E        VFPFJ_01149 eukaryotic translation initiation factor subunit eIF-4F	K03260 EIF4G; translation initiation factor 4G 
E        VFPFJ_04740 RNA recognition motif containing protein	K03258 EIF4B; translation initiation factor 4B 
E        VFPFJ_07982 ATP-dependent RNA helicase ded1	K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7] 
E        VFPFJ_00332 DEAD/DEAH box RNA helicase	K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7] 
E        VFPFJ_08833 GYF domain-containingprotein	K18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein 
E        VFPFJ_02737 polyadenylate-binding protein	K13126 PABPC; polyadenylate-binding protein 
E        VFPFJ_03008 antiviral helicase SKI2	K12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6] 
E        VFPFJ_00861 activating signal cointegrator 1 complex subunit 3	K18664 SLH1; antiviral helicase SLH1 [EC:5.6.2.6] 
E        VFPFJ_03115 PUA RNA binding domain-containingprotein	K07575 MCTS; malignant T-cell-amplified sequence 
E        VFPFJ_03516 density-regulated protein DRP1	K24272 DENR; density-regulated protein 
D      APOBEC1-ACF complex
D      Other transport factors
E        VFPFJ_03419 RNA binding protein Pym	K14294 WIBG; partner of Y14 and mago 
E        VFPFJ_09505 heterogeneous nuclear ribonucleoprotein HRP1	K14411 MSI; RNA-binding protein Musashi 
E        VFPFJ_09252 elongation factor Tu GTP binding domain-containingprotein	K14416 HBS1; elongation factor 1 alpha-like protein 
E        VFPFJ_02474 translation factor pelota	K06965 PELO; protein pelota 
E        VFPFJ_09500 RNA recognition motif domain-containingprotein	K14396 PABPN1; polyadenylate-binding protein 2 
E        VFPFJ_08512 ATP-dependent RNA helicase DBP5	K18655 DDX19; ATP-dependent RNA helicase DDX19/DBP5 [EC:5.6.2.7] 
E        VFPFJ_08913 pre-mRNA splicing factor syf-1	K12867 SYF1; pre-mRNA-splicing factor SYF1 
E        VFPFJ_02984 DNA-binding SAP	K18732 SARNP; SAP domain-containing ribonucleoprotein 
E        VFPFJ_02547 Ran exchange factor Prp20/Pim1	K11493 RCC1; regulator of chromosome condensation 
E        VFPFJ_02879 regulator of chromosome condensation	K11493 RCC1; regulator of chromosome condensation 
E        VFPFJ_03807 regulator of chromosome condensation (RCC1)-like protein	K11493 RCC1; regulator of chromosome condensation 
E        VFPFJ_06461 SAC3/GANP domain-containingprotein	K23802 LENG8; SAC3 family protein LENG8/THP3 
C    Surveillance factors
D      Surveillance complex
E        VFPFJ_05449 eukaryotic peptide chain release factor subunit 1	K03265 ETF1; peptide chain release factor subunit 1 
E        VFPFJ_02658 eukaryotic peptide chain release factor GTP-binding subunit	K03267 ERF3; peptide chain release factor subunit 3 
E        VFPFJ_00649 nonsense-mediated mRNA decay factor (Upf2)	K14327 UPF2; regulator of nonsense transcripts 2 
E        VFPFJ_07122 nonsense-mediated mRNA decay protein Upf3	K14328 UPF3; regulator of nonsense transcripts 3 
D      Protein phosphatase 2A
E        VFPFJ_00881 serine/threonine-protein phosphatase PP2A catalytic subunit	K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16] 
E        VFPFJ_01159 protein phosphatase PP2A regulatory subunit A	K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A 
E        VFPFJ_03210 protein phosphatase PP2A regulatory subunit B	K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B 
E        VFPFJ_06589 serine/threonine-protein phosphatase 2A regulatory subunit delta 1 isoform	K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B' 
D      Other surveillance factors
E        VFPFJ_05454 telomerase activating protein Est1	K14409 SMG7; protein SMG7 
E        VFPFJ_08833 GYF domain-containingprotein	K18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein 
E        VFPFJ_02423 GTP-binding protein 1	K24887 GTPBP1; GTP-binding protein 1 
C    Factors involved in mRNA localization
D      Cargo complex
E        VFPFJ_03509 protein PUF6	K14844 PUF6; pumilio homology domain family member 6 
E        VFPFJ_03590 KH domain RNA binding protein	K18738 HEK; heterogeneous nuclear rnp K-like protein 
E        VFPFJ_05506 KH domain-containingRNA-binding protein	K18738 HEK; heterogeneous nuclear rnp K-like protein 
E        VFPFJ_07707 class V myosin	K10357 MYO5; myosin V 
D      Factors that have mRNA localization signals
D      Trans-acting binding proteins
E        VFPFJ_03735 far upstream element-binding protein 2	K13210 FUBP; far upstream element-binding protein 
E        VFPFJ_00453 elongation factor 1-alpha	K03231 EEF1A; elongation factor 1-alpha 
E        VFPFJ_07785 elongation factor 1 gamma domain-containing protein	K03233 EEF1G; elongation factor 1-gamma 
D      Other mRNA localization factors
E        VFPFJ_08040 cell wall biogenesis protein phosphatase Ssd1	K18748 SSD1; protein SSD1 
C    mRNA cycle factors
D      Common to processing body (P body) and stress granule
E        VFPFJ_07987 exonuclease Kem1	K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-] 
E        VFPFJ_01915 eukaryotic translation initiation factor 2c	K11593 ELF2C; eukaryotic translation initiation factor 2C 
E        VFPFJ_10316 RNA interference and silencing protein	K11593 ELF2C; eukaryotic translation initiation factor 2C 
E        VFPFJ_02797 stem cell self-renewal protein Piwi	K11593 ELF2C; eukaryotic translation initiation factor 2C 
E        VFPFJ_07997 eukaryotic translation initiation factor 4E-4	K03259 EIF4E; translation initiation factor 4E 
E        VFPFJ_09994 translation Initiation Factor Eif4e	K03259 EIF4E; translation initiation factor 4E 
E        VFPFJ_07982 ATP-dependent RNA helicase ded1	K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7] 
E        VFPFJ_00332 DEAD/DEAH box RNA helicase	K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7] 
E        VFPFJ_01816 ATP-dependent RNA helicase DHH1	K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7] 
E        VFPFJ_06743 Like-Sm ribonucleoprotein (LSM)-related domain-containingprotein	K18749 LSM14; protein LSM14 
E        VFPFJ_02968 importin beta-2 subunit	K18752 TNPO1; transportin-1 
E        VFPFJ_05454 telomerase activating protein Est1	K14409 SMG7; protein SMG7 
E        VFPFJ_00264 protein kinase DC2	K04345 PKA; protein kinase A [EC:2.7.11.11] 
E        VFPFJ_05669 cAMP-dependent protein kinase type 2	K04345 PKA; protein kinase A [EC:2.7.11.11] 
E        VFPFJ_03285 La domain-containingfamily	K18757 LARP1; la-related protein 1 
D      P-body specific factors
E        VFPFJ_06243 mRNA-decapping enzyme 2	K12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62] 
E        VFPFJ_06704 small nuclear ribonucleoprotein (LSM1)	K12620 LSM1; U6 snRNA-associated Sm-like protein LSm1 
E        VFPFJ_02424 U6 snRNA-associated Sm-like protein LSm3	K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3 
E        VFPFJ_00705 U6 snRNA-associated Sm-like protein LSM4	K12623 LSM4; U6 snRNA-associated Sm-like protein LSm4 
E        VFPFJ_05114 U6 snRNA-associated Sm-like protein LSm6	K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6 
E        VFPFJ_02935 LSM domain-containing protein	K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7 
E        VFPFJ_07707 class V myosin	K10357 MYO5; myosin V 
E        VFPFJ_07101 tubulin alpha-1 chain	K07374 TUBA; tubulin alpha 
E        VFPFJ_05180 tubulin alpha-1 chain	K07374 TUBA; tubulin alpha 
E        VFPFJ_02676 Ccr4-Not transcription complex subunit (NOT1)	K12604 CNOT1; CCR4-NOT transcription complex subunit 1 
E        VFPFJ_00984 peptidase cysteine/serine, trypsin-like protein	K12605 CNOT2; CCR4-NOT transcription complex subunit 2 
E        VFPFJ_04438 CCR4-NOT transcription complex	K12580 CNOT3; CCR4-NOT transcription complex subunit 3 
E        VFPFJ_04140 RNA recognition domain-containing protein	K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27] 
E        VFPFJ_09209 transcription factor	K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4] 
E        VFPFJ_01320 CCR4-NOT transcription complex subunit 7	K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8 
E        VFPFJ_02654 PAB-dependent poly(A)-specific ribonuclease subunit PAN2	K12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4] 
E        VFPFJ_02936 PABP-dependent poly(A) nuclease 3	K12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3 
E        VFPFJ_06538 topisomerase II associated protein	K12617 PATL1; DNA topoisomerase 2-associated protein PAT1 
E        VFPFJ_01265 hypothetical protein	K12615 EDC3; enhancer of mRNA-decapping protein 3 
E        VFPFJ_00649 nonsense-mediated mRNA decay factor (Upf2)	K14327 UPF2; regulator of nonsense transcripts 2 
E        VFPFJ_07122 nonsense-mediated mRNA decay protein Upf3	K14328 UPF3; regulator of nonsense transcripts 3 
E        VFPFJ_03393 RNA polymerase Rpb7-like domain-containing protein	K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7 
D      Stress granule specific factors
E        VFPFJ_01144 nuclear and cytoplasmic polyadenylated RNA-binding protein pub1	K13201 TIA1; nucleolysin TIA-1/TIAR 
E        VFPFJ_02737 polyadenylate-binding protein	K13126 PABPC; polyadenylate-binding protein 
E        VFPFJ_05750 ntf2 and rrm domain-containing protein	K24983 G3BP2; Ras GTPase-activating protein-binding protein 2 
E        VFPFJ_02230 eukaryotic translation initiation factor 2A	K15026 EIF2A; translation initiation factor 2A 
E        VFPFJ_10246 eukaryotic translation initiation factor 3 subunit B	K03253 EIF3B; translation initiation factor 3 subunit B 
E        VFPFJ_05350 eukaryotic initiation factor 4A	K03257 EIF4A; translation initiation factor 4A 
E        VFPFJ_08304 eukaryotic initiation factor 4A	K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7] 
E        VFPFJ_04740 RNA recognition motif containing protein	K03258 EIF4B; translation initiation factor 4B 
E        VFPFJ_01149 eukaryotic translation initiation factor subunit eIF-4F	K03260 EIF4G; translation initiation factor 4G 
E        VFPFJ_09582 guanine nucleotide-binding protein beta subunit-like protein	K14753 RACK1; guanine nucleotide-binding protein subunit beta-2-like 1 protein 
E        VFPFJ_05000 mRNA export factor mex67	K14284 NXF; nuclear RNA export factor 
E        VFPFJ_04922 histone deacetylase clr3	K11407 HDAC6; histone deacetylase 6 [EC:3.5.1.98] 
B  mRNA degradation factors
C    5'-3' decay
D      Decapping complex
E        VFPFJ_06243 mRNA-decapping enzyme 2	K12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62] 
E        VFPFJ_01816 ATP-dependent RNA helicase DHH1	K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7] 
E        VFPFJ_01265 hypothetical protein	K12615 EDC3; enhancer of mRNA-decapping protein 3 
E        VFPFJ_06538 topisomerase II associated protein	K12617 PATL1; DNA topoisomerase 2-associated protein PAT1 
D      Lsm complex
E        VFPFJ_06704 small nuclear ribonucleoprotein (LSM1)	K12620 LSM1; U6 snRNA-associated Sm-like protein LSm1 
E        VFPFJ_02424 U6 snRNA-associated Sm-like protein LSm3	K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3 
E        VFPFJ_00705 U6 snRNA-associated Sm-like protein LSM4	K12623 LSM4; U6 snRNA-associated Sm-like protein LSm4 
E        VFPFJ_05114 U6 snRNA-associated Sm-like protein LSm6	K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6 
E        VFPFJ_02935 LSM domain-containing protein	K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7 
D      5' exonucleases
E        VFPFJ_07987 exonuclease Kem1	K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-] 
E        VFPFJ_06641 5'-3' exoribonuclease 2	K12619 XRN2; 5'-3' exoribonuclease 2 [EC:3.1.13.-] 
D      Other 5'-3' decay factors
E        VFPFJ_00886 mRNA decapping hydrolase	K12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59] 
C    3'-5' decay
D      Core exosome factors
E        VFPFJ_07926 exosomal core protein CSL4	K07573 CSL4; exosome complex component CSL4 
E        VFPFJ_08616 exoribonuclease	K03679 RRP4; exosome complex component RRP4 
E        VFPFJ_00483 exosome complex exonuclease RRP40	K03681 RRP40; exosome complex component RRP40 
E        VFPFJ_11013 exosome complex exonuclease RRP41	K11600 RRP41; exosome complex component RRP41 
E        VFPFJ_03554 ribosomal protein S5 domain-containing protein	K12590 RRP46; exosome complex component RRP46 
E        VFPFJ_05980 3' exoribonuclease family protein	K12586 RRP43; exosome complex component RRP43 
E        VFPFJ_01253 3' exoribonuclease	K03678 RRP45; exosome complex component RRP45 
D      Exosome cofactors
E        VFPFJ_03437 mitotic control protein dis3	K12585 DIS3; exosome complex exonuclease DIS3/RRP44 [EC:3.1.13.-] 
E        VFPFJ_02110 3'-5' exonuclease domain-containing protein	K12591 RRP6; exosome complex exonuclease RRP6 [EC:3.1.13.-] 
E        VFPFJ_00399 Sas10/Utp3/C1D family protein	K12592 C1D; exosome complex protein LRP1 
D      TRAMP complex
E        VFPFJ_02538 PAP/25A-associated	K03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19] 
E        VFPFJ_08752 zinc knuckle domain-containingprotein	K12597 AIR1_2; protein AIR1/2 
E        VFPFJ_07358 ATP-dependent RNA helicase DOB1	K12598 MTR4; ATP-dependent RNA helicase DOB1 [EC:5.6.2.6] 
D      Ski complex
E        VFPFJ_03008 antiviral helicase SKI2	K12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6] 
E        VFPFJ_02181 translation repressor/antiviral protein Ski3	K12600 SKI3; superkiller protein 3 
E        VFPFJ_06823 meiotic recombination protein Ski8/Rec14	K12601 SKI8; superkiller protein 8 
D      Ccr4-NOT complex
E        VFPFJ_09209 transcription factor	K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4] 
E        VFPFJ_02676 Ccr4-Not transcription complex subunit (NOT1)	K12604 CNOT1; CCR4-NOT transcription complex subunit 1 
E        VFPFJ_00984 peptidase cysteine/serine, trypsin-like protein	K12605 CNOT2; CCR4-NOT transcription complex subunit 2 
E        VFPFJ_04438 CCR4-NOT transcription complex	K12580 CNOT3; CCR4-NOT transcription complex subunit 3 
E        VFPFJ_04140 RNA recognition domain-containing protein	K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27] 
E        VFPFJ_01320 CCR4-NOT transcription complex subunit 7	K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8 
E        VFPFJ_07870 ABC transporter	K12608 CAF16; CCR4-NOT complex subunit CAF16 
D      Pan complex
E        VFPFJ_02654 PAB-dependent poly(A)-specific ribonuclease subunit PAN2	K12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4] 
E        VFPFJ_02936 PABP-dependent poly(A) nuclease 3	K12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3 
D      Other 3'-5' decay factors
E        VFPFJ_05547 CAF1 family ribonuclease domain-containing protein	K01148 PARN; poly(A)-specific ribonuclease [EC:3.1.13.4] 
E        VFPFJ_00886 mRNA decapping hydrolase	K12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59] 
E        VFPFJ_05765 hypothetical protein	K26109 NRDE2; nuclear exosome regulator NRDE2 
E        VFPFJ_06626 protein VTS1	K27407 VTS1; RNA-binding protein VTS1 
C    Other degradation factors
D      RNases
#
A<b>Prokaryotic type</b>
B  Bacterial mRNA degradation factors
C    RNA degradosome components
D      Ribonucreases
E        VFPFJ_06929 nucleolar RNAse III	K03685 rnc; ribonuclease III [EC:3.1.26.3] 
E        VFPFJ_05189 exonuclease family protein	K13288 orn; oligoribonuclease [EC:3.1.-.-] 
D      Helicases
D      Other RNA degradosome components
E        VFPFJ_03236 enolase	K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] 
E        VFPFJ_11730 6-phosphofructokinase	K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] 
E        VFPFJ_06004 6-phosphofructokinase alpha subunit	K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] 
C    Other RNA degradation factors
D      Chaperones
E        VFPFJ_00955 heat shock protein SSC1, mitochondrial precursor	K04043 dnaK; molecular chaperone DnaK 
E        VFPFJ_06940 heat shock protein 60, mitochondrial precursor	K04077 groEL; chaperonin GroEL [EC:5.6.1.7] 
D      Others
D      Bacterial Small RNA Regulators
B  Archeal mRNA degradation factors
C    Exosome components
D      Core exosome
E        VFPFJ_08616 exoribonuclease	K03679 RRP4; exosome complex component RRP4 
E        VFPFJ_07926 exosomal core protein CSL4	K07573 CSL4; exosome complex component CSL4 
D      Cofactors
E        VFPFJ_11013 exosome complex exonuclease RRP41	K11600 RRP41; exosome complex component RRP41 
D      Others
!
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#Last updated: April 25, 2024