+E Replication protein KO
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DNA Replication Proteins - Pseudogulbenkiania sp. NH8B
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AEukaryotic type
B DNA Replication Initiation Factors
C pre-RC (pre-replication complex)
C CDK (cyclin dependent kinase)
C DDK (Dbf-4 dependent kinase)
C GINS complex
C Other initiation factors
B DNA Replication Elongation Factors
C DNA polymerase alpha / primase complex
C DNA polymerase epsilon complex
C DNA polymerase delta complex
C DNA polymerase gamma complex (mitochondrial)
C RPA (replication protein A)
C RFC (replication factor C)
C RNase H
D NH8B_1079 rnhA; ribonuclease H K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
C Other elongation factors
B DNA Replication Termination Factors
C DNA methylation enzymes
D NH8B_1674 hypothetical protein K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D NH8B_0946 C-5 cytosine-specific DNA methylase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D NH8B_0011 DNA cytosine methylase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D NH8B_2105 cytosine-specific methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
C Prevention of re-replication factors
C Telomere proteins
D Shelterin complex
D TERB1-TERB2-MAJIN complex
D CST complex (animals)
D CST complex (yeast)
D RIF proteins
D SIR proteins
C Telomerase complex (animals)
D Dyskerin complex
C Telomerase complex (fungi)
D Sm core complex
C ELG1-RFC complex
C MRN complex
C Other termination factors
B DNA Topoisomerases
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AProkaryotic type
B DNA Replication Initiation Factors
C Initiation factors (bacterial)
D NH8B_1652 histone-like DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
D NH8B_2600 histone-like DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
D NH8B_2083 histone-like DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
D NH8B_1305 ihfA; integration host factor, alpha subunit K04764 ihfA; integration host factor subunit alpha
D NH8B_3225 ihfB; integration host factor, beta subunit K05788 ihfB; integration host factor subunit beta
D NH8B_0001 dnaA; chromosomal replication initiator protein DnaA K02313 dnaA; chromosomal replication initiator protein
D NH8B_2594 replicative DNA helicase K02314 dnaB; replicative DNA helicase [EC:5.6.2.3]
D NH8B_0973 dnaC; DNA replication protein DnaC K02315 dnaC; DNA replication protein DnaC
D NH8B_3470 dnaG; DNA primase K02316 dnaG; DNA primase [EC:2.7.7.101]
D NH8B_1268 single-strand binding protein K03111 ssb; single-strand DNA-binding protein
C Initiation factors (archaeal)
B DNA Replication Elongation Factors
C Elongation factors (bacterial)
D DNA polymerase III holoenzyme
E NH8B_3051 dnaE; DNA polymerase III, alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E NH8B_0002 dnaN; DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E NH8B_1726 holC; DNA polymerase III, chi subunit HolC K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
E NH8B_3904 pol_III; DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E NH8B_0742 holB; DNA polymerase III, delta prime subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E NH8B_1563 dnaQ; DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E NH8B_3093 dnaQ; DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E NH8B_1080 dnaQ; DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E NH8B_3989 dnaQ; DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E NH8B_3278 dnaQ; DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E NH8B_2862 dnaX; DNA polymerase III, subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D RNase H
E NH8B_1079 rnhA; ribonuclease H K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
E NH8B_2555 rnhB; ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4]
D Other elongation factors
E NH8B_3742 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E NH8B_0475 ligA; DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
C Elongation factors (archaeal)
D B-family DNA polymerases
D D-family DNA polymerases
D RNase H
E NH8B_1079 rnhA; ribonuclease H K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
E NH8B_2555 rnhB; ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4]
D RFC (replication factor C)
D Other elongation factors
B DNA Replication Termination Factors
C Terminus site-binding protein
C DNA methylation enzymes
C Prevention of re-replication factors
D NH8B_0783 DnaA regulatory inactivator Hda K10763 hda; DnaA-homolog protein
B DNA Topoisomerases
C NH8B_2228 gyrA; DNA gyrase, A subunit K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
C NH8B_0003 gyrB; DNA gyrase, B subunit K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
C NH8B_3981 DNA topoisomerase IV, A subunit K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2]
C NH8B_3405 DNA topoisomerase IV, B subunit K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2]
C NH8B_0280 topA; DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: November 2, 2022