+D GENES KO
#
KEGG Orthology (KO) - Rickettsia felis
%
!
A09100 Metabolism
B
B 09101 Carbohydrate metabolism
C 00010 Glycolysis / Gluconeogenesis [PATH:rfe00010]
D RF_0735 ppdK; Pyruvate,phosphate dikinase precursor K01006 ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1]
D RF_1020 pdhA; Pyruvate dehydrogenase e1 component, alpha subunit precursor K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
D RF_1019 pdhB; Pyruvate dehydrogenase E1 component, beta subunit precursor K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
D RF_0761 pdhC; Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
D RF_0807 lpdA2; Dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D RF_1270 lpdA1; Dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
C 00020 Citrate cycle (TCA cycle) [PATH:rfe00020]
D RF_1338 gltA; Citrate synthase I K01647 CS; citrate synthase [EC:2.3.3.1]
D RF_1264 acnA; Aconitate hydratase K01681 ACO; aconitate hydratase [EC:4.2.1.3]
D RF_1015 icd; Isocitrate dehydrogenase, NADP-dependent K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]
D RF_1092 sucA; 2-oxoglutarate dehydrogenase E1 component K00164 OGDH; 2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2]
D RF_1093 sucB; Dihydrolipoamide acetyltransferase component K00658 DLST; 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61]
D RF_0807 lpdA2; Dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D RF_1270 lpdA1; Dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D RF_0664 sucD; Succinyl-CoA synthetase alpha chain K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]
D RF_0665 sucC; Succinyl-CoA synthetase beta chain K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]
D RF_1159 sdhA; Succinate dehydrogenase flavoprotein subunit K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
D RF_0136 sdhB; Succinate dehydrogenase iron-sulfur protein K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
D RF_1163 sdhC; Succinate dehydrogenase cytochrome b-556 subunit K00241 sdhC; succinate dehydrogenase cytochrome b subunit
D RF_1161 sdhD; Succinate dehydrogenase hydrophobic membrane anchor protein K00242 sdhD; succinate dehydrogenase membrane anchor subunit
D RF_0273 fumC; Fumarate hydratase K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]
D RF_0590 mdh; Malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D RF_1020 pdhA; Pyruvate dehydrogenase e1 component, alpha subunit precursor K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
D RF_1019 pdhB; Pyruvate dehydrogenase E1 component, beta subunit precursor K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
D RF_0761 pdhC; Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
C 00030 Pentose phosphate pathway [PATH:rfe00030]
D RF_0486 lacA; Ribose-5-phosphate isomerase K01808 rpiB; ribose 5-phosphate isomerase B [EC:5.3.1.6]
D RF_0078 prs; Ribose-phosphate pyrophosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
C 00040 Pentose and glucuronate interconversions
D RF_1245 udg; UDP-glucose 6-dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
C 00051 Fructose and mannose metabolism [PATH:rfe00051]
D RF_0716 exoC; Phosphomannomutase K01840 manB; phosphomannomutase [EC:5.4.2.8]
D RF_0241 manC; Mannose-1-phosphate guanylyltransferase K00971 manC; mannose-1-phosphate guanylyltransferase [EC:2.7.7.13]
D RF_0486 lacA; Ribose-5-phosphate isomerase K01808 rpiB; ribose 5-phosphate isomerase B [EC:5.3.1.6]
C 00052 Galactose metabolism
D RF_0539 capD; CapD protein K17716 capD; UDP-glucose 4-epimerase [EC:5.1.3.2]
C 00053 Ascorbate and aldarate metabolism
D RF_1245 udg; UDP-glucose 6-dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
C 00500 Starch and sucrose metabolism [PATH:rfe00500]
D RF_0203 Beta-glucosidase K05349 bglX; beta-glucosidase [EC:3.2.1.21]
C 00520 Amino sugar and nucleotide sugar metabolism [PATH:rfe00520]
D RF_0798 glmU; UDP-N-acetylglucosamine pyrophosphorylase K11528 glmU; UDP-N-acetylglucosamine pyrophosphorylase [EC:2.7.7.23]
D RF_0945 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]
D RF_1036 murB; UDP-N-acetylenolpyruvoylglucosamine reductase K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98]
D RF_0540 rffE; UDP-N-acetylglucosamine 2-epimerase K01791 wecB; UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing) [EC:5.1.3.14]
D RF_1245 udg; UDP-glucose 6-dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D RF_0539 capD; CapD protein K17716 capD; UDP-glucose 4-epimerase [EC:5.1.3.2]
D RF_0716 exoC; Phosphomannomutase K01840 manB; phosphomannomutase [EC:5.4.2.8]
D RF_0241 manC; Mannose-1-phosphate guanylyltransferase K00971 manC; mannose-1-phosphate guanylyltransferase [EC:2.7.7.13]
C 00620 Pyruvate metabolism [PATH:rfe00620]
D RF_1020 pdhA; Pyruvate dehydrogenase e1 component, alpha subunit precursor K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
D RF_1019 pdhB; Pyruvate dehydrogenase E1 component, beta subunit precursor K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
D RF_0761 pdhC; Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
D RF_0807 lpdA2; Dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D RF_1270 lpdA1; Dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D RF_0097 ackA; Acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1]
D RF_0096 pta; Phosphate acetyltransferase Pta K00625 pta; phosphate acetyltransferase [EC:2.3.1.8]
D RF_0584 tme; Malate oxidoreductase and phosphate acetyltransferase K00029 maeB; malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) [EC:1.1.1.40]
D RF_0590 mdh; Malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D RF_0273 fumC; Fumarate hydratase K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]
D RF_0735 ppdK; Pyruvate,phosphate dikinase precursor K01006 ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1]
D RF_0163 paaJ; Acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
C 00630 Glyoxylate and dicarboxylate metabolism [PATH:rfe00630]
D RF_0590 mdh; Malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D RF_1338 gltA; Citrate synthase I K01647 CS; citrate synthase [EC:2.3.3.1]
D RF_1264 acnA; Aconitate hydratase K01681 ACO; aconitate hydratase [EC:4.2.1.3]
D RF_0163 paaJ; Acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D RF_0153 phbB; Acetoacetyl-CoA reductase K00023 phbB; acetoacetyl-CoA reductase [EC:1.1.1.36]
D RF_0419 accC; Acetyl-CoA carboxylase, biotin carboxylase K01965 PCCA; propionyl-CoA carboxylase alpha chain [EC:6.4.1.3]
D RF_0418 pccB; Propionyl-CoA carboxylase beta chain precursor K01966 PCCB; propionyl-CoA carboxylase beta chain [EC:6.4.1.3 2.1.3.15]
D RF_0728 glnA; Glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D RF_1188 glyA; Glycine/serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D RF_0807 lpdA2; Dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D RF_1270 lpdA1; Dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
C 00640 Propanoate metabolism [PATH:rfe00640]
D RF_0097 ackA; Acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1]
D RF_0096 pta; Phosphate acetyltransferase Pta K00625 pta; phosphate acetyltransferase [EC:2.3.1.8]
D RF_0807 lpdA2; Dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D RF_1270 lpdA1; Dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D RF_0890 fadB; 3-hydroxyacyl-CoA dehydrogenase FadB K01782 fadJ; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3]
D RF_0419 accC; Acetyl-CoA carboxylase, biotin carboxylase K01965 PCCA; propionyl-CoA carboxylase alpha chain [EC:6.4.1.3]
D RF_0418 pccB; Propionyl-CoA carboxylase beta chain precursor K01966 PCCB; propionyl-CoA carboxylase beta chain [EC:6.4.1.3 2.1.3.15]
D RF_0665 sucC; Succinyl-CoA synthetase beta chain K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]
D RF_0664 sucD; Succinyl-CoA synthetase alpha chain K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]
C 00650 Butanoate metabolism [PATH:rfe00650]
D RF_0163 paaJ; Acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D RF_0890 fadB; 3-hydroxyacyl-CoA dehydrogenase FadB K01782 fadJ; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3]
D RF_0162 phbC; Poly-beta-hydroxybutyrate polymerase K03821 phaC; poly[(R)-3-hydroxyalkanoate] polymerase subunit PhaC [EC:2.3.1.304]
D RF_1298 phaC; Poly(3-hydroxyalkanoate) synthetase K03821 phaC; poly[(R)-3-hydroxyalkanoate] polymerase subunit PhaC [EC:2.3.1.304]
D RF_0238 Poly-beta-hydroxyalkanoate depolymerase K05973 phaZ; poly(3-hydroxybutyrate) depolymerase [EC:3.1.1.75]
D RF_0153 phbB; Acetoacetyl-CoA reductase K00023 phbB; acetoacetyl-CoA reductase [EC:1.1.1.36]
D RF_1159 sdhA; Succinate dehydrogenase flavoprotein subunit K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
D RF_0136 sdhB; Succinate dehydrogenase iron-sulfur protein K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
D RF_1163 sdhC; Succinate dehydrogenase cytochrome b-556 subunit K00241 sdhC; succinate dehydrogenase cytochrome b subunit
D RF_1161 sdhD; Succinate dehydrogenase hydrophobic membrane anchor protein K00242 sdhD; succinate dehydrogenase membrane anchor subunit
D RF_0684 gabD; Succinate semialdehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
D RF_0374 scoA; Succinyl-CoA:3-ketoacid-coenzyme A transferase K01028 scoA; 3-oxoacid CoA-transferase subunit A [EC:2.8.3.5]
D RF_0373 scoB; Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit B K01029 scoB; 3-oxoacid CoA-transferase subunit B [EC:2.8.3.5]
D RF_1389 Oxidoreductase K00019 BDH1; 3-hydroxybutyrate dehydrogenase [EC:1.1.1.30]
C 00660 C5-Branched dibasic acid metabolism
D RF_0665 sucC; Succinyl-CoA synthetase beta chain K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]
D RF_0664 sucD; Succinyl-CoA synthetase alpha chain K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]
C 00562 Inositol phosphate metabolism [PATH:rfe00562]
D RF_1048 suhB; Extragenic suppressor protein SuhB K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25]
B
B 09102 Energy metabolism
C 00190 Oxidative phosphorylation [PATH:rfe00190]
D RF_0567 nuoA; NADH dehydrogenase I chain A K00330 nuoA; NADH-quinone oxidoreductase subunit A [EC:7.1.1.2]
D RF_0566 nuoB; NADH dehydrogenase I chain B K00331 nuoB; NADH-quinone oxidoreductase subunit B [EC:7.1.1.2]
D RF_0565 nuoC; NADH dehydrogenase I chain C K00332 nuoC; NADH-quinone oxidoreductase subunit C [EC:7.1.1.2]
D RF_0564 nuoD; NADH dehydrogenase I chain D K00333 nuoD; NADH-quinone oxidoreductase subunit D [EC:7.1.1.2]
D RF_0563 nuoE; NADH dehydrogenase I chain E K00334 nuoE; NADH-quinone oxidoreductase subunit E [EC:7.1.1.2]
D RF_1178 nuoF; NADH dehydrogenase I chain F K00335 nuoF; NADH-quinone oxidoreductase subunit F [EC:7.1.1.2]
D RF_1262 nuoG; NADH dehydrogenase I chain G K00336 nuoG; NADH-quinone oxidoreductase subunit G [EC:7.1.1.2]
D RF_1261 nuoH; NADH dehydrogenase I chain H K00337 nuoH; NADH-quinone oxidoreductase subunit H [EC:7.1.1.2]
D RF_1260 nuoI; NADH dehydrogenase I chain I K00338 nuoI; NADH-quinone oxidoreductase subunit I [EC:7.1.1.2]
D RF_1255 nuoJ; NADH dehydrogenase I chain J K00339 nuoJ; NADH-quinone oxidoreductase subunit J [EC:7.1.1.2]
D RF_1256 nuoK; NADH dehydrogenase I chain K K00340 nuoK; NADH-quinone oxidoreductase subunit K [EC:7.1.1.2]
D RF_1257 nuoL1; NADH dehydrogenase I chain L K00341 nuoL; NADH-quinone oxidoreductase subunit L [EC:7.1.1.2]
D RF_1258 nuoM; NADH dehydrogenase I chain M K00342 nuoM; NADH-quinone oxidoreductase subunit M [EC:7.1.1.2]
D RF_0854 nuoN1; NADH:ubiquinone oxidoreductase subunit 2 (chain N) K00343 nuoN; NADH-quinone oxidoreductase subunit N [EC:7.1.1.2]
D RF_1159 sdhA; Succinate dehydrogenase flavoprotein subunit K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
D RF_0136 sdhB; Succinate dehydrogenase iron-sulfur protein K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
D RF_1163 sdhC; Succinate dehydrogenase cytochrome b-556 subunit K00241 sdhC; succinate dehydrogenase cytochrome b subunit
D RF_1161 sdhD; Succinate dehydrogenase hydrophobic membrane anchor protein K00242 sdhD; succinate dehydrogenase membrane anchor subunit
D RF_1010 petA; Ubiquinol-cytochrome c reductase, iron-sulfur subunit K00411 UQCRFS1; ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:7.1.1.8]
D RF_1009 petB; Cytochrome b K00412 CYTB; ubiquinol-cytochrome c reductase cytochrome b subunit
D RF_1007 fbcH; Cytochrome c1, heme protein precursor K00413 CYC1; ubiquinol-cytochrome c reductase cytochrome c1 subunit
D RF_0550 cyoB; Protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141]
D RF_1076 coxC; Cytochrome c oxidase subunit III K02276 coxC; cytochrome c oxidase subunit III [EC:7.1.1.9]
D RF_0627 coxA; Cytochrome c oxidase polypeptide I K02274 coxA; cytochrome c oxidase subunit I [EC:7.1.1.9]
D RF_0629 coxB; Cytochrome c oxidase polypeptide II K02275 coxB; cytochrome c oxidase subunit II [EC:7.1.1.9]
D RF_0494 cox11; Cytochrome c oxidase assembly protein cox11 K02258 COX11; cytochrome c oxidase assembly protein subunit 11
D RF_1024 coxW; Cytochrome c oxidase assembly protein K02259 COX15; heme a synthase [EC:1.17.99.9]
D RF_0333 cydA; Cytochrome d ubiquinol oxidase subunit I K00425 cydA; cytochrome bd ubiquinol oxidase subunit I [EC:7.1.1.7]
D RF_0336 cydB; Cytochrome d ubiquinol oxidase subunit II K00426 cydB; cytochrome bd ubiquinol oxidase subunit II [EC:7.1.1.7]
D RF_1030 cycM; Cytochrome c K08738 CYC; cytochrome c
D RF_1268 atpA; ATP synthase alpha chain K02111 ATPF1A; F-type H+/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1]
D RF_1266 atpD; ATP synthase beta chain K02112 ATPF1B; F-type H+/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1]
D RF_1267 atpG; ATP synthase gamma chain K02115 ATPF1G; F-type H+-transporting ATPase subunit gamma
D RF_1269 atpH; ATP synthase delta chain K02113 ATPF1D; F-type H+-transporting ATPase subunit delta
D RF_1265 atpC; ATP synthase epsilon chain K02114 ATPF1E; F-type H+-transporting ATPase subunit epsilon
D RF_0030 atpB; ATP synthase A chain K02108 ATPF0A; F-type H+-transporting ATPase subunit a
D RF_0027 atpF; ATP synthase B chain precursor K02109 ATPF0B; F-type H+-transporting ATPase subunit b
D RF_0028 atpX; ATP synthase B chain K02109 ATPF0B; F-type H+-transporting ATPase subunit b
D RF_0029 atpE; ATP synthase C chain K02110 ATPF0C; F-type H+-transporting ATPase subunit c
D RF_0962 ppa; Inorganic pyrophosphatase K01507 ppa; inorganic pyrophosphatase [EC:3.6.1.1]
C 00195 Photosynthesis
C 00196 Photosynthesis - antenna proteins
C 00710 Carbon fixation in photosynthetic organisms
C 00720 Carbon fixation pathways in prokaryotes
C 00680 Methane metabolism [PATH:rfe00680]
D RF_1188 glyA; Glycine/serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D RF_0590 mdh; Malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D RF_0097 ackA; Acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1]
D RF_0096 pta; Phosphate acetyltransferase Pta K00625 pta; phosphate acetyltransferase [EC:2.3.1.8]
C 00910 Nitrogen metabolism [PATH:rfe00910]
D RF_1213 NAD-specific glutamate dehydrogenase K15371 GDH2; glutamate dehydrogenase [EC:1.4.1.2]
D RF_0728 glnA; Glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
C 00920 Sulfur metabolism
D RF_0482 cysQ; 3'(2'),5'-bisphosphate nucleotidase K01082 cysQ; 3'(2'), 5'-bisphosphate nucleotidase [EC:3.1.3.7]
B
B 09103 Lipid metabolism
C 00061 Fatty acid biosynthesis [PATH:rfe00061]
D RF_1223 acpP; Acyl carrier protein K02078 acpP; acyl carrier protein
D RF_0171 fabD; Malonyl CoA-acyl carrier protein transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]
D RF_1235 fabH; 3-oxoacyl-[acyl carrier protein] synthase III K00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180]
D RF_1224 fabF; 3-oxoacyl-[acyl carrier protein] synthase II K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]
D RF_1222 fabG; 3-oxoacyl reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D RF_0007 fabZ; (3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase K02372 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59]
D RF_0575 fabI; Enoyl-[acyl carrier protein] reductase K00208 fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10]
C 00062 Fatty acid elongation
C 00071 Fatty acid degradation [PATH:rfe00071]
D RF_0163 paaJ; Acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D RF_0890 fadB; 3-hydroxyacyl-CoA dehydrogenase FadB K01782 fadJ; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3]
D RF_0417 aas; 2-acylglycerophosphoethanolamine acyltransferase K05939 aas; acyl-[acyl-carrier-protein]-phospholipid O-acyltransferase / long-chain-fatty-acid--[acyl-carrier-protein] ligase [EC:2.3.1.40 6.2.1.20]
C 00073 Cutin, suberine and wax biosynthesis
C 00100 Steroid biosynthesis
C 00120 Primary bile acid biosynthesis
C 00121 Secondary bile acid biosynthesis
C 00140 Steroid hormone biosynthesis
C 00561 Glycerolipid metabolism
D RF_0825 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]
C 00564 Glycerophospholipid metabolism [PATH:rfe00564]
D RF_0677 gpsA; Glycerol-3-phosphate dehydrogenase K00057 gpsA; glycerol-3-phosphate dehydrogenase (NAD(P)+) [EC:1.1.1.94]
D RF_0825 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]
D RF_1297 Phospholipase D (PLD) superfamily protein K17717 pld; phospholipase D [EC:3.1.4.4]
D RF_0417 aas; 2-acylglycerophosphoethanolamine acyltransferase K05939 aas; acyl-[acyl-carrier-protein]-phospholipid O-acyltransferase / long-chain-fatty-acid--[acyl-carrier-protein] ligase [EC:2.3.1.40 6.2.1.20]
D RF_0655 cdsA; Phosphatidate cytidylyltransferase K00981 E2.7.7.41; phosphatidate cytidylyltransferase [EC:2.7.7.41]
D RF_1045 pssA; CDP-diacylglycerol--serine O-phosphatidyltransferase K17103 CHO1; CDP-diacylglycerol---serine O-phosphatidyltransferase [EC:2.7.8.8]
D RF_1046 psd; Phosphatidylserine decarboxylase K01613 psd; phosphatidylserine decarboxylase [EC:4.1.1.65]
D RF_1197 pgpA; Phosphatidylglycerophosphatase A K01095 pgpA; phosphatidylglycerophosphatase A [EC:3.1.3.27]
D RF_0130 pgsA; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase K08744 CRLS; cardiolipin synthase (CMP-forming) [EC:2.7.8.41]
C 00565 Ether lipid metabolism
D RF_1297 Phospholipase D (PLD) superfamily protein K17717 pld; phospholipase D [EC:3.1.4.4]
C 00600 Sphingolipid metabolism
C 00590 Arachidonic acid metabolism
C 00591 Linoleic acid metabolism
C 00592 alpha-Linolenic acid metabolism
C 01040 Biosynthesis of unsaturated fatty acids [PATH:rfe01040]
D RF_0145 aco1; Acyl-CoA desaturase 1 K00507 SCD; stearoyl-CoA desaturase (Delta-9 desaturase) [EC:1.14.19.1]
B
B 09104 Nucleotide metabolism
C 00230 Purine metabolism [PATH:rfe00230]
D RF_0078 prs; Ribose-phosphate pyrophosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
D RF_0339 purC; Phosphoribosylaminoimidazole-succinocarboxamide synthase K01923 purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:6.3.2.6]
D RF_0729 Conserved hypothetical protein K05810 LACC1; purine-nucleoside/S-methyl-5'-thioadenosine phosphorylase / adenosine deaminase [EC:2.4.2.1 2.4.2.28 3.5.4.4]
D RF_0120 ndk; Nucleoside diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
D RF_1229 gmk; Guanylate kinase K00942 gmk; guanylate kinase [EC:2.7.4.8]
D RF_0709 nrdA; Ribonucleoside-diphosphate reductase alpha chain K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D RF_0710 nrdB; Ribonucleoside-diphosphate reductase beta chain K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D RF_0110 dgt; Deoxyguanosinetriphosphate triphosphohydrolase K01129 dgt; dGTPase [EC:3.1.5.1]
D RF_0384 spoT15; Guanosine polyphosphate pyrophosphohydrolases/synthetases homolog K21138 HDDC3; guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [EC:3.1.7.2]
D RF_0884 spoT9; Guanosine polyphosphate pyrophosphohydrolases/synthetases homolog K21138 HDDC3; guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [EC:3.1.7.2]
D RF_0438 spoT7; Guanosine polyphosphate pyrophosphohydrolases/synthetases homolog K21138 HDDC3; guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [EC:3.1.7.2]
D RF_0440 spoT8; Guanosine polyphosphate pyrophosphohydrolases/synthetases homolog K21138 HDDC3; guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [EC:3.1.7.2]
D RF_0450 spoT1; Guanosine polyphosphate pyrophosphohydrolases/synthetases homolog K21138 HDDC3; guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [EC:3.1.7.2]
D RF_0953 spoT3; Guanosine polyphosphate pyrophosphohydrolases/synthetases homolog K21138 HDDC3; guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [EC:3.1.7.2]
D RF_0470 gppA; Guanosine pentaphosphate phosphohydrolase K01524 ppx-gppA; exopolyphosphatase / guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase [EC:3.6.1.11 3.6.1.40]
D RF_0299 adk; Adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3]
C 00240 Pyrimidine metabolism [PATH:rfe00240]
D RF_1126 pyrH; Uridylate kinase K09903 pyrH; uridylate kinase [EC:2.7.4.22]
D RF_0120 ndk; Nucleoside diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
D RF_1293 maf; Nucleotide-binding protein implicated in inhibition of septum formation K06287 yhdE; nucleoside triphosphate pyrophosphatase [EC:3.6.1.-]
D RF_0593 pyrG; CTP synthase K01937 pyrG; CTP synthase [EC:6.3.4.2]
D RF_0770 cmk; Cytidylate kinase K00945 cmk; CMP/dCMP kinase [EC:2.7.4.25]
D RF_0054 dcd; Deoxycytidine triphosphate deaminase K01494 dcd; dCTP deaminase [EC:3.5.4.13]
D RF_0709 nrdA; Ribonucleoside-diphosphate reductase alpha chain K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D RF_0710 nrdB; Ribonucleoside-diphosphate reductase beta chain K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D RF_p13 tmk; Thymidylate kinase K00943 tmk; dTMP kinase [EC:2.7.4.9]
D RF_pd13 tmk; Thymidylate kinase K00943 tmk; dTMP kinase [EC:2.7.4.9]
D RF_0234 tmk; Thymidylate kinase K00943 tmk; dTMP kinase [EC:2.7.4.9]
D RF_0620 dut; Deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D RF_0491 thyX; Thymidylate synthase ThyX K03465 thyX; thymidylate synthase (FAD) [EC:2.1.1.148]
B
B 09105 Amino acid metabolism
C 00250 Alanine, aspartate and glutamate metabolism [PATH:rfe00250]
D RF_0074 aatA; Aspartate aminotransferase A K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D RF_0684 gabD; Succinate semialdehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
D RF_1213 NAD-specific glutamate dehydrogenase K15371 GDH2; glutamate dehydrogenase [EC:1.4.1.2]
D RF_0728 glnA; Glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
C 00260 Glycine, serine and threonine metabolism [PATH:rfe00260]
D RF_1200 lysC; Aspartokinase K00928 lysC; aspartate kinase [EC:2.7.2.4]
D RF_0512 asd; Aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D RF_1188 glyA; Glycine/serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D RF_1334 hemA; 5-aminolevulinic acid synthase K00643 E2.3.1.37; 5-aminolevulinate synthase [EC:2.3.1.37]
D RF_0807 lpdA2; Dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D RF_1270 lpdA1; Dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D RF_1045 pssA; CDP-diacylglycerol--serine O-phosphatidyltransferase K17103 CHO1; CDP-diacylglycerol---serine O-phosphatidyltransferase [EC:2.7.8.8]
D RF_0691 tdcB; Threonine dehydratase K01754 E4.3.1.19; threonine dehydratase [EC:4.3.1.19]
C 00270 Cysteine and methionine metabolism [PATH:rfe00270]
D RF_0729 Conserved hypothetical protein K05810 LACC1; purine-nucleoside/S-methyl-5'-thioadenosine phosphorylase / adenosine deaminase [EC:2.4.2.1 2.4.2.28 3.5.4.4]
D RF_0138 Site-specific DNA methylase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D RF_0137 Site-specific DNA methylase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D RF_1200 lysC; Aspartokinase K00928 lysC; aspartate kinase [EC:2.7.2.4]
D RF_0512 asd; Aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D RF_0659 ilvE; Branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D RF_0074 aatA; Aspartate aminotransferase A K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D RF_0590 mdh; Malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
C 00280 Valine, leucine and isoleucine degradation [PATH:rfe00280]
D RF_0659 ilvE; Branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D RF_0807 lpdA2; Dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D RF_1270 lpdA1; Dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D RF_0890 fadB; 3-hydroxyacyl-CoA dehydrogenase FadB K01782 fadJ; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3]
D RF_0419 accC; Acetyl-CoA carboxylase, biotin carboxylase K01965 PCCA; propionyl-CoA carboxylase alpha chain [EC:6.4.1.3]
D RF_0418 pccB; Propionyl-CoA carboxylase beta chain precursor K01966 PCCB; propionyl-CoA carboxylase beta chain [EC:6.4.1.3 2.1.3.15]
D RF_0374 scoA; Succinyl-CoA:3-ketoacid-coenzyme A transferase K01028 scoA; 3-oxoacid CoA-transferase subunit A [EC:2.8.3.5]
D RF_0373 scoB; Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit B K01029 scoB; 3-oxoacid CoA-transferase subunit B [EC:2.8.3.5]
D RF_0163 paaJ; Acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
C 00290 Valine, leucine and isoleucine biosynthesis [PATH:rfe00290]
D RF_0691 tdcB; Threonine dehydratase K01754 E4.3.1.19; threonine dehydratase [EC:4.3.1.19]
D RF_0659 ilvE; Branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
C 00300 Lysine biosynthesis [PATH:rfe00300]
D RF_1200 lysC; Aspartokinase K00928 lysC; aspartate kinase [EC:2.7.2.4]
D RF_0512 asd; Aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D RF_0660 dapA; Dihydrodipicolinate synthase K01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7]
D RF_1133 dapB; Dihydrodipicolinate reductase K00215 dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8]
D RF_1073 dapD; 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase K00674 dapD; 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [EC:2.3.1.117]
D RF_1376 dapE; Succinyl-diaminopimelate desuccinylase K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18]
D RF_0645 dapF; Diaminopimelate epimerase K01778 dapF; diaminopimelate epimerase [EC:5.1.1.7]
D RF_0368 murE; UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase K01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13]
D RF_0369 murF; UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]
C 00310 Lysine degradation [PATH:rfe00310]
D RF_1093 sucB; Dihydrolipoamide acetyltransferase component K00658 DLST; 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61]
D RF_0807 lpdA2; Dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D RF_1270 lpdA1; Dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D RF_0890 fadB; 3-hydroxyacyl-CoA dehydrogenase FadB K01782 fadJ; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3]
D RF_0163 paaJ; Acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D RF_0684 gabD; Succinate semialdehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
C 00220 Arginine biosynthesis [PATH:rfe00220]
D RF_0728 glnA; Glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D RF_1213 NAD-specific glutamate dehydrogenase K15371 GDH2; glutamate dehydrogenase [EC:1.4.1.2]
D RF_0074 aatA; Aspartate aminotransferase A K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D RF_0086 argB; Acetylglutamate kinase K00930 argB; acetylglutamate kinase [EC:2.7.2.8]
C 00330 Arginine and proline metabolism
D RF_0074 aatA; Aspartate aminotransferase A K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
C 00340 Histidine metabolism
C 00350 Tyrosine metabolism [PATH:rfe00350]
D RF_0074 aatA; Aspartate aminotransferase A K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D RF_0684 gabD; Succinate semialdehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
C 00360 Phenylalanine metabolism
D RF_0074 aatA; Aspartate aminotransferase A K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
C 00380 Tryptophan metabolism [PATH:rfe00380]
D RF_1093 sucB; Dihydrolipoamide acetyltransferase component K00658 DLST; 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61]
D RF_0807 lpdA2; Dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D RF_1270 lpdA1; Dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D RF_0890 fadB; 3-hydroxyacyl-CoA dehydrogenase FadB K01782 fadJ; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3]
D RF_0163 paaJ; Acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
C 00400 Phenylalanine, tyrosine and tryptophan biosynthesis [PATH:rfe00400]
D RF_0074 aatA; Aspartate aminotransferase A K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
B
B 09106 Metabolism of other amino acids
C 00410 beta-Alanine metabolism
D RF_0890 fadB; 3-hydroxyacyl-CoA dehydrogenase FadB K01782 fadJ; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3]
C 00430 Taurine and hypotaurine metabolism [PATH:rfe00430]
D RF_1213 NAD-specific glutamate dehydrogenase K15371 GDH2; glutamate dehydrogenase [EC:1.4.1.2]
D RF_0096 pta; Phosphate acetyltransferase Pta K00625 pta; phosphate acetyltransferase [EC:2.3.1.8]
D RF_0097 ackA; Acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1]
C 00440 Phosphonate and phosphinate metabolism
D RF_1371 phnP; Metal-dependent hydrolases of the beta-lactamase superfamily I K06167 phnP; phosphoribosyl 1,2-cyclic phosphate phosphodiesterase [EC:3.1.4.55]
C 00450 Selenocompound metabolism [PATH:rfe00450]
D RF_0681 trxB1; Thioredoxin reductase K00384 trxB; thioredoxin reductase (NADPH) [EC:1.8.1.9]
D RF_0700 trxB2; Thioredoxin reductase K00384 trxB; thioredoxin reductase (NADPH) [EC:1.8.1.9]
D RF_0235 metG; Methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
C 00460 Cyanoamino acid metabolism [PATH:rfe00460]
D RF_0203 Beta-glucosidase K05349 bglX; beta-glucosidase [EC:3.2.1.21]
D RF_1188 glyA; Glycine/serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
C 00470 D-Amino acid metabolism [PATH:rfe00470]
D RF_0079 alr; Alanine racemase K01775 alr; alanine racemase [EC:5.1.1.1]
D RF_1035 ddlB; D-alanine--D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]
D RF_0634 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]
D RF_0645 dapF; Diaminopimelate epimerase K01778 dapF; diaminopimelate epimerase [EC:5.1.1.7]
C 00480 Glutathione metabolism [PATH:rfe00480]
D RF_1143 pepA; Aminopeptidase A K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1]
D RF_0736 Glutathione S-transferase K00799 GST; glutathione S-transferase [EC:2.5.1.18]
D RF_1015 icd; Isocitrate dehydrogenase, NADP-dependent K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]
B
B 09107 Glycan biosynthesis and metabolism
C 00510 N-Glycan biosynthesis
C 00513 Various types of N-glycan biosynthesis
C 00512 Mucin type O-glycan biosynthesis
C 00515 Mannose type O-glycan biosynthesis
C 00514 Other types of O-glycan biosynthesis
C 00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate
C 00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin
C 00533 Glycosaminoglycan biosynthesis - keratan sulfate
C 00531 Glycosaminoglycan degradation
C 00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
C 00601 Glycosphingolipid biosynthesis - lacto and neolacto series
C 00603 Glycosphingolipid biosynthesis - globo and isoglobo series
C 00604 Glycosphingolipid biosynthesis - ganglio series
C 00511 Other glycan degradation
C 00540 Lipopolysaccharide biosynthesis [PATH:rfe00540]
D RF_0006 lpxA; Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase K00677 lpxA; UDP-N-acetylglucosamine acyltransferase [EC:2.3.1.129]
D RF_1028 lpxC; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase K02535 lpxC; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [EC:3.5.1.108]
D RF_0008 lpxD; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase K02536 lpxD; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase [EC:2.3.1.191]
D RF_0178 unknown K09949 lpxI; UDP-2,3-diacylglucosamine hydrolase [EC:3.6.1.54]
D RF_0519 lpxB; Lipid-A-disaccharide synthase K00748 lpxB; lipid-A-disaccharide synthase [EC:2.4.1.182]
D RF_0196 lpxK; Tetraacyldisaccharide 4'-kinase K00912 lpxK; tetraacyldisaccharide 4'-kinase [EC:2.7.1.130]
D RF_0720 kpsF; KpsF protein K06041 kdsD; arabinose-5-phosphate isomerase [EC:5.3.1.13]
D RF_0113 kdsA; 3-deoxy-8-phosphooctulonate synthase K01627 kdsA; 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase) [EC:2.5.1.55]
D RF_0594 kdsB; 3-deoxy-manno-octulosonate cytidylyltransferase K00979 kdsB; 3-deoxy-manno-octulosonate cytidylyltransferase (CMP-KDO synthetase) [EC:2.7.7.38]
D RF_0072 kdtA; 3-deoxy-D-manno-octulosonic-acid transferase K02527 kdtA; 3-deoxy-D-manno-octulosonic-acid transferase [EC:2.4.99.12 2.4.99.13 2.4.99.14 2.4.99.15]
D RF_0197 htrB; Lipid A biosynthesis lauroyl acyltransferase K02517 lpxL; Kdo2-lipid IVA lauroyltransferase/acyltransferase [EC:2.3.1.241 2.3.1.-]
C 00542 O-Antigen repeat unit biosynthesis
C 00541 O-Antigen nucleotide sugar biosynthesis [PATH:rfe00541]
D RF_0539 capD; CapD protein K17716 capD; UDP-glucose 4-epimerase [EC:5.1.3.2]
D RF_1245 udg; UDP-glucose 6-dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D RF_0538 dTDP-4-dehydrorhamnose reductase K00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133]
D RF_0716 exoC; Phosphomannomutase K01840 manB; phosphomannomutase [EC:5.4.2.8]
D RF_0241 manC; Mannose-1-phosphate guanylyltransferase K00971 manC; mannose-1-phosphate guanylyltransferase [EC:2.7.7.13]
D RF_0540 rffE; UDP-N-acetylglucosamine 2-epimerase K01791 wecB; UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing) [EC:5.1.3.14]
C 00550 Peptidoglycan biosynthesis [PATH:rfe00550]
D RF_0945 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]
D RF_1036 murB; UDP-N-acetylenolpyruvoylglucosamine reductase K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98]
D RF_1037 murC; UDP-N-acetylmuramate--alanine ligase K01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8]
D RF_0634 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]
D RF_0368 murE; UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase K01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13]
D RF_1035 ddlB; D-alanine--D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]
D RF_0369 murF; UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]
D RF_0656 uppS; Undecaprenyl pyrophosphate synthetase K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31]
D RF_0370 mraY1; Phospho-N-acetylmuramoyl-pentapeptide-transferase K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13]
D RF_0636 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]
D RF_1276 mrcA; Penicillin-binding protein 1A family K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]
D RF_1069 pbpC; Bifunctional penicillin-binding protein 1C K05367 pbpC; penicillin-binding protein 1C [EC:2.4.99.28]
D RF_0900 pbpA1; Penicillin-binding protein K05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4]
D RF_0902 pbpA2; Penicillin-binding protein K03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4]
D RF_0609 dacF; Penicillin-binding protein DacF precursor K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4]
C 00552 Teichoic acid biosynthesis [PATH:rfe00552]
D RF_0227 unknown K07271 licD; lipopolysaccharide cholinephosphotransferase [EC:2.7.8.-]
C 00571 Lipoarabinomannan (LAM) biosynthesis
C 00572 Arabinogalactan biosynthesis - Mycobacterium
C 00543 Exopolysaccharide biosynthesis
B
B 09108 Metabolism of cofactors and vitamins
C 00730 Thiamine metabolism [PATH:rfe00730]
D RF_0845 iscS; Cysteine desulfurase IscS K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D RF_0846 spl1; Nifs protein homolog K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D RF_0299 adk; Adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3]
C 00740 Riboflavin metabolism
D RF_0859 ubiX; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129]
C 00750 Vitamin B6 metabolism
C 00760 Nicotinate and nicotinamide metabolism [PATH:rfe00760]
D RF_0675 ppnK; Probable inorganic polyphosphate/ATP-NAD kinase K00858 ppnK; NAD+ kinase [EC:2.7.1.23]
D RF_1361 pntA2; NAD(P) transhydrogenase subunit alpha K00324 pntA; proton-translocating NAD(P)+ transhydrogenase subunit alpha [EC:7.1.1.1]
D RF_1362 pntA1; NAD(P) transhydrogenase subunit alpha K00324 pntA; proton-translocating NAD(P)+ transhydrogenase subunit alpha [EC:7.1.1.1]
D RF_0059 pntB; NAD(p) transhydrogenase subunit beta K00325 pntB; proton-translocating NAD(P)+ transhydrogenase subunit beta [EC:7.1.1.1]
D RF_0684 gabD; Succinate semialdehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
C 00770 Pantothenate and CoA biosynthesis [PATH:rfe00770]
D RF_0177 coaE; Dephospho-CoA kinase K00859 coaE; dephospho-CoA kinase [EC:2.7.1.24]
D RF_0943 acpS; Holo-[acyl carrier protein] synthase K00997 acpS; holo-[acyl-carrier protein] synthase [EC:2.7.8.7]
D RF_0659 ilvE; Branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
C 00780 Biotin metabolism [PATH:rfe00780]
D RF_1224 fabF; 3-oxoacyl-[acyl carrier protein] synthase II K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]
D RF_1222 fabG; 3-oxoacyl reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D RF_0007 fabZ; (3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase K02372 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59]
D RF_0575 fabI; Enoyl-[acyl carrier protein] reductase K00208 fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10]
D RF_0527 bioB; Biotin synthase K01012 bioB; biotin synthase [EC:2.8.1.6]
D RF_0744 birA; Biotin--acetyl-CoA-carboxylase ligase K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]
C 00785 Lipoic acid metabolism [PATH:rfe00785]
D RF_1383 lipB; Probable lipoate-protein ligase B K03801 lipB; lipoyl(octanoyl) transferase [EC:2.3.1.181]
D RF_1187 lipA; Lipoic acid synthetase K03644 lipA; lipoyl synthase [EC:2.8.1.8]
D RF_0807 lpdA2; Dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D RF_1270 lpdA1; Dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D RF_1020 pdhA; Pyruvate dehydrogenase e1 component, alpha subunit precursor K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
D RF_1019 pdhB; Pyruvate dehydrogenase E1 component, beta subunit precursor K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
D RF_0761 pdhC; Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
D RF_1092 sucA; 2-oxoglutarate dehydrogenase E1 component K00164 OGDH; 2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2]
D RF_1093 sucB; Dihydrolipoamide acetyltransferase component K00658 DLST; 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61]
C 00790 Folate biosynthesis [PATH:rfe00790]
D RF_0599 folE; GTP cyclohydrolase I K01495 GCH1; GTP cyclohydrolase IA [EC:3.5.4.16]
D RF_0039 folKP; Folate synthesis bifunctional protein K13941 folKP; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase / dihydropteroate synthase [EC:2.7.6.3 2.5.1.15]
D RF_0038 Dihydrofolate reductase FolA K00287 DHFR; dihydrofolate reductase [EC:1.5.1.3]
D RF_0740 folC; Folylpolyglutamate synthase K11754 folC; dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17]
D RF_1094 6-pyruvoyl tetrahydropterin synthase K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]
D RF_0997 Putative pterin-4-alpha-carbinolamine dehydratase (PHS) K01724 PCBD; 4a-hydroxytetrahydrobiopterin dehydratase [EC:4.2.1.96]
D RF_0351 nrdG; Organic radical activating enzymes K10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3]
D RF_0217 exsB; Trans-regulatory protein ExsB K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20]
D RF_0057 unknown K06879 queF; 7-cyano-7-deazaguanine reductase [EC:1.7.1.13]
C 00670 One carbon pool by folate [PATH:rfe00670]
D RF_0038 Dihydrofolate reductase FolA K00287 DHFR; dihydrofolate reductase [EC:1.5.1.3]
D RF_0699 folD; Methylenetetrahydrofolate dehydrogenase K01491 folD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9]
D RF_1188 glyA; Glycine/serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D RF_0325 fmt; Methionyl-tRNA formyltransferase K00604 MTFMT; methionyl-tRNA formyltransferase [EC:2.1.2.9]
D RF_0491 thyX; Thymidylate synthase ThyX K03465 thyX; thymidylate synthase (FAD) [EC:2.1.1.148]
D RF_0808 5-Formyltetrahydrofolate cyclo-ligase K01934 MTHFS; 5-formyltetrahydrofolate cyclo-ligase [EC:6.3.3.2]
C 00830 Retinol metabolism
C 00860 Porphyrin metabolism [PATH:rfe00860]
D RF_1334 hemA; 5-aminolevulinic acid synthase K00643 E2.3.1.37; 5-aminolevulinate synthase [EC:2.3.1.37]
D RF_0413 gltX2; Glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D RF_0529 gltX1; Glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D RF_0856 hemB; Delta-aminolevulinic acid dehydratase K01698 hemB; porphobilinogen synthase [EC:4.2.1.24]
D RF_0817 hemC; Porphobilinogen deaminase K01749 hemC; hydroxymethylbilane synthase [EC:2.5.1.61]
D RF_1400 hemE; Uroporphyrinogen decarboxylase K01599 hemE; uroporphyrinogen decarboxylase [EC:4.1.1.37]
D RF_1396 hemF; Coproporphyrinogen III oxidase precursor K00228 CPOX; coproporphyrinogen III oxidase [EC:1.3.3.3]
D RF_1398 Conserved hypothetical protein K08973 hemJ; protoporphyrinogen IX oxidase [EC:1.3.99.-]
D RF_1399 hemH; Probable ferrochelatase K01772 hemH; protoporphyrin/coproporphyrin ferrochelatase [EC:4.98.1.1 4.99.1.9]
D RF_0550 cyoB; Protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141]
D RF_1024 coxW; Cytochrome c oxidase assembly protein K02259 COX15; heme a synthase [EC:1.17.99.9]
C 00130 Ubiquinone and other terpenoid-quinone biosynthesis [PATH:rfe00130]
D RF_0231 ubiA; 4-hydroxybenzoate octaprenyltransferase K03179 ubiA; 4-hydroxybenzoate polyprenyltransferase [EC:2.5.1.39]
D RF_1299 ubiD; UbiD family decarboxylases K03182 ubiD; 4-hydroxy-3-polyprenylbenzoate decarboxylase [EC:4.1.1.98]
D RF_0859 ubiX; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129]
D RF_0414 ubiG; Ubiquinone biosynthesis O-methyltransferase K00568 ubiG; 2-polyprenyl-6-hydroxyphenyl methylase / 3-demethylubiquinone-9 3-methyltransferase [EC:2.1.1.222 2.1.1.64]
D RF_0893 ubiH; 2-polyprenyl-6-methoxyphenol 4-hydroxylase K03185 ubiH; 2-octaprenyl-6-methoxyphenol hydroxylase [EC:1.14.13.-]
D RF_0243 ubiE; Ubiquinone/menaquinone biosynthesis methlytransferase UbiE K03183 ubiE; demethylmenaquinone methyltransferase / 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase [EC:2.1.1.163 2.1.1.201]
D RF_1077 coq7; Ubiquinone biosynthesis protein Coq7 K06134 COQ7; 3-demethoxyubiquinol 3-hydroxylase [EC:1.14.99.60]
D RF_0372 Tryptophan repressor binding protein K03809 wrbA; NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2]
B
B 09109 Metabolism of terpenoids and polyketides
C 00900 Terpenoid backbone biosynthesis [PATH:rfe00900]
D RF_0163 paaJ; Acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D RF_0859 ubiX; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129]
D RF_0785 fni; Isopentenyl-diphosphate delta-isomerase K01823 idi; isopentenyl-diphosphate Delta-isomerase [EC:5.3.3.2]
D RF_0839 ispB; Octaprenyl-diphosphate synthase K02523 ispB; octaprenyl-diphosphate synthase [EC:2.5.1.90]
D RF_0656 uppS; Undecaprenyl pyrophosphate synthetase K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31]
C 00902 Monoterpenoid biosynthesis
C 00909 Sesquiterpenoid and triterpenoid biosynthesis
C 00904 Diterpenoid biosynthesis
C 00906 Carotenoid biosynthesis
C 00905 Brassinosteroid biosynthesis
C 00981 Insect hormone biosynthesis
C 00908 Zeatin biosynthesis
C 00903 Limonene degradation
C 00907 Pinene, camphor and geraniol degradation [PATH:rfe00907]
D RF_0890 fadB; 3-hydroxyacyl-CoA dehydrogenase FadB K01782 fadJ; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3]
C 01052 Type I polyketide structures
C 00522 Biosynthesis of 12-, 14- and 16-membered macrolides
C 01051 Biosynthesis of ansamycins
C 01059 Biosynthesis of enediyne antibiotics
C 01056 Biosynthesis of type II polyketide backbone
C 01057 Biosynthesis of type II polyketide products
C 00253 Tetracycline biosynthesis
C 00523 Polyketide sugar unit biosynthesis
D RF_0538 dTDP-4-dehydrorhamnose reductase K00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133]
C 01054 Nonribosomal peptide structures
C 01053 Biosynthesis of siderophore group nonribosomal peptides
C 01055 Biosynthesis of vancomycin group antibiotics
B
B 09110 Biosynthesis of other secondary metabolites
C 00940 Phenylpropanoid biosynthesis
C 00945 Stilbenoid, diarylheptanoid and gingerol biosynthesis
C 00941 Flavonoid biosynthesis
C 00944 Flavone and flavonol biosynthesis
C 00942 Anthocyanin biosynthesis
C 00943 Isoflavonoid biosynthesis
C 00946 Degradation of flavonoids [PATH:rfe00946]
D RF_0203 Beta-glucosidase K05349 bglX; beta-glucosidase [EC:3.2.1.21]
C 00901 Indole alkaloid biosynthesis
C 00403 Indole diterpene alkaloid biosynthesis
C 00950 Isoquinoline alkaloid biosynthesis
C 00960 Tropane, piperidine and pyridine alkaloid biosynthesis
C 00996 Biosynthesis of various alkaloids
C 00232 Caffeine metabolism
C 00965 Betalain biosynthesis
C 00966 Glucosinolate biosynthesis
C 00402 Benzoxazinoid biosynthesis
C 00311 Penicillin and cephalosporin biosynthesis
C 00332 Carbapenem biosynthesis
C 00261 Monobactam biosynthesis [PATH:rfe00261]
D RF_1200 lysC; Aspartokinase K00928 lysC; aspartate kinase [EC:2.7.2.4]
D RF_0512 asd; Aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D RF_0660 dapA; Dihydrodipicolinate synthase K01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7]
D RF_1133 dapB; Dihydrodipicolinate reductase K00215 dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8]
C 00331 Clavulanic acid biosynthesis
C 00521 Streptomycin biosynthesis [PATH:rfe00521]
D RF_1048 suhB; Extragenic suppressor protein SuhB K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25]
D RF_0538 dTDP-4-dehydrorhamnose reductase K00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133]
C 00524 Neomycin, kanamycin and gentamicin biosynthesis
C 00525 Acarbose and validamycin biosynthesis
C 00401 Novobiocin biosynthesis
D RF_0074 aatA; Aspartate aminotransferase A K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
C 00404 Staurosporine biosynthesis
C 00405 Phenazine biosynthesis
C 00333 Prodigiosin biosynthesis
D RF_0171 fabD; Malonyl CoA-acyl carrier protein transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]
D RF_1222 fabG; 3-oxoacyl reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D RF_0575 fabI; Enoyl-[acyl carrier protein] reductase K00208 fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10]
C 00254 Aflatoxin biosynthesis
C 00998 Biosynthesis of various antibiotics
D RF_1223 acpP; Acyl carrier protein K02078 acpP; acyl carrier protein
C 00999 Biosynthesis of various plant secondary metabolites
D RF_0203 Beta-glucosidase K05349 bglX; beta-glucosidase [EC:3.2.1.21]
C 00997 Biosynthesis of various other secondary metabolites
B
B 09111 Xenobiotics biodegradation and metabolism
C 00362 Benzoate degradation [PATH:rfe00362]
D RF_0617 Protocatechuate-3,4-dioxygenase, beta subunit K00449 pcaH; protocatechuate 3,4-dioxygenase, beta subunit [EC:1.13.11.3]
D RF_0890 fadB; 3-hydroxyacyl-CoA dehydrogenase FadB K01782 fadJ; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3]
D RF_0163 paaJ; Acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
C 00627 Aminobenzoate degradation
D RF_0859 ubiX; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129]
C 00364 Fluorobenzoate degradation
C 00625 Chloroalkane and chloroalkene degradation
C 00361 Chlorocyclohexane and chlorobenzene degradation
C 00623 Toluene degradation
C 00622 Xylene degradation
C 00633 Nitrotoluene degradation
C 00642 Ethylbenzene degradation
C 00643 Styrene degradation
C 00791 Atrazine degradation
C 00930 Caprolactam degradation [PATH:rfe00930]
D RF_0890 fadB; 3-hydroxyacyl-CoA dehydrogenase FadB K01782 fadJ; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3]
C 00363 Bisphenol degradation
C 00621 Dioxin degradation
C 00626 Naphthalene degradation
C 00624 Polycyclic aromatic hydrocarbon degradation
D RF_0617 Protocatechuate-3,4-dioxygenase, beta subunit K00449 pcaH; protocatechuate 3,4-dioxygenase, beta subunit [EC:1.13.11.3]
C 00365 Furfural degradation
C 00984 Steroid degradation
C 00980 Metabolism of xenobiotics by cytochrome P450
C 00982 Drug metabolism - cytochrome P450
C 00983 Drug metabolism - other enzymes
B
B 09112 Not included in regular maps
C 09113 Global maps only
#
A09120 Genetic Information Processing
B
B 09121 Transcription
C 03020 RNA polymerase [PATH:rfe03020]
D RF_1146 rpoB; DNA-directed RNA polymerase beta chain K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
D RF_1145 rpoC; DNA-directed RNA polymerase beta prime chain K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
D RF_0302 rpoA; DNA-directed RNA polymerase alpha chain K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
D RF_0944 rpoZ; DNA-directed RNA polymerase omega chain K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
C 03022 Basal transcription factors
C 03040 Spliceosome
B
B 09122 Translation
C 03010 Ribosome [PATH:rfe03010]
D RF_0771 rpsA; 30S ribosomal protein S1 K02945 RP-S1; small subunit ribosomal protein S1
D RF_0069 rpsB; 30S ribosomal protein S2 K02967 RP-S2; small subunit ribosomal protein S2
D RF_0284 rpsC; 30S ribosomal protein S3 K02982 RP-S3; small subunit ribosomal protein S3
D RF_0549 rpsD; 30S ribosomal protein S4 K02986 RP-S4; small subunit ribosomal protein S4
D RF_0295 rpsE; 30S ribosomal protein S5 K02988 RP-S5; small subunit ribosomal protein S5
D RF_0143 rpsF; 30S ribosomal protein S6 K02990 RP-S6; small subunit ribosomal protein S6
D RF_1154 rpsG; 30S ribosomal protein S7 K02992 RP-S7; small subunit ribosomal protein S7
D RF_0292 rpsH; 30S ribosomal protein S8 K02994 RP-S8; small subunit ribosomal protein S8
D RF_0995 rpsI; 30S ribosomal protein S9 K02996 RP-S9; small subunit ribosomal protein S9
D RF_0277 rpsJ; 30S ribosomal protein S10 K02946 RP-S10; small subunit ribosomal protein S10
D RF_0301 rpsK; 30S ribosomal protein S11 K02948 RP-S11; small subunit ribosomal protein S11
D RF_1155 rpsL; 30S ribosomal protein S12 K02950 RP-S12; small subunit ribosomal protein S12
D RF_0300 rpsM; 30S ribosomal protein S13 K02952 RP-S13; small subunit ribosomal protein S13
D RF_0291 rpsN; 30S ribosomal protein S14 K02954 RP-S14; small subunit ribosomal protein S14
D RF_0722 rpsO; 30S ribosomal protein S15 K02956 RP-S15; small subunit ribosomal protein S15
D RF_1385 rpsP; 30S ribosomal protein S16 K02959 RP-S16; small subunit ribosomal protein S16
D RF_0287 rpsQ; 30S ribosomal protein S17 K02961 RP-S17; small subunit ribosomal protein S17
D RF_0142 rpsR; 30S ribosomal protein S18 K02963 RP-S18; small subunit ribosomal protein S18
D RF_0282 rpsS; 30S ribosomal protein S19 K02965 RP-S19; small subunit ribosomal protein S19
D RF_0304 rpsT; 30S ribosomal protein S20 K02968 RP-S20; small subunit ribosomal protein S20
D RF_0426 rpsU; 30S ribosomal protein S21 K02970 RP-S21; small subunit ribosomal protein S21
D RF_1149 rplA; 50S ribosomal protein L1 K02863 RP-L1; large subunit ribosomal protein L1
D RF_0281 rplB; 50S ribosomal protein L2 K02886 RP-L2; large subunit ribosomal protein L2
D RF_0278 rplC; 50S ribosomal protein L3 K02906 RP-L3; large subunit ribosomal protein L3
D RF_0279 rplD; 50S ribosomal protein L4 K02926 RP-L4; large subunit ribosomal protein L4
D RF_0290 rplE; 50S ribosomal protein L5 K02931 RP-L5; large subunit ribosomal protein L5
D RF_0293 rplF; 50S ribosomal protein L6 K02933 RP-L6; large subunit ribosomal protein L6
D RF_1147 rplL; 50S ribosomal protein L7/L12 K02935 RP-L7; large subunit ribosomal protein L7/L12
D RF_0141 rplI; 50S ribosomal protein L9 K02939 RP-L9; large subunit ribosomal protein L9
D RF_1148 rplJ; 50S ribosomal protein L10 K02864 RP-L10; large subunit ribosomal protein L10
D RF_1150 rplK; 50S ribosomal protein L11 K02867 RP-L11; large subunit ribosomal protein L11
D RF_0994 rplM; 50S ribosomal protein L13 K02871 RP-L13; large subunit ribosomal protein L13
D RF_0288 rplN; 50S ribosomal protein L14 K02874 RP-L14; large subunit ribosomal protein L14
D RF_0297 rplO; 50S ribosomal protein L15 K02876 RP-L15; large subunit ribosomal protein L15
D RF_0285 rplP; 50S ribosomal protein L16 K02878 RP-L16; large subunit ribosomal protein L16
D RF_0303 rplQ; 50S ribosomal protein L17 K02879 RP-L17; large subunit ribosomal protein L17
D RF_0294 rplR; 50S ribosomal protein L18 K02881 RP-L18; large subunit ribosomal protein L18
D RF_0100 rplS; 50S ribosomal protein L19 K02884 RP-L19; large subunit ribosomal protein L19
D RF_0349 rplT; 50S ribosomal protein L20 K02887 RP-L20; large subunit ribosomal protein L20
D RF_1198 rplU; 50S ribosomal protein L21 K02888 RP-L21; large subunit ribosomal protein L21
D RF_0283 rplV; 50S ribosomal protein L22 K02890 RP-L22; large subunit ribosomal protein L22
D RF_0280 rplW; 50S ribosomal protein L23 K02892 RP-L23; large subunit ribosomal protein L23
D RF_0289 rplX; 50S ribosomal protein L24 K02895 RP-L24; large subunit ribosomal protein L24
D RF_0352 rplY; 50S ribosomal protein L25 K02897 RP-L25; large subunit ribosomal protein L25
D RF_1199 rpmA; 50S ribosomal protein L27 K02899 RP-L27; large subunit ribosomal protein L27
D RF_0083 rpmB; 50S ribosomal protein L28 K02902 RP-L28; large subunit ribosomal protein L28
D RF_0286 rpmC; 50S ribosomal protein L29 K02904 RP-L29; large subunit ribosomal protein L29
D RF_0296 rpmD; 50S ribosomal protein L30 K02907 RP-L30; large subunit ribosomal protein L30
D RF_0084 rpmE; 50S ribosomal protein L31 K02909 RP-L31; large subunit ribosomal protein L31
D RF_1236 rpmF; 50S ribosomal protein L32 K02911 RP-L32; large subunit ribosomal protein L32
D RF_1386 rpmG; 50S ribosomal protein L33 K02913 RP-L33; large subunit ribosomal protein L33
D RF_0348 rpmH; 50S ribosomal protein L34 K02914 RP-L34; large subunit ribosomal protein L34
D RF_0350 rpmI; 50S ribosomal protein L35 K02916 RP-L35; large subunit ribosomal protein L35
D RF_0800 rpmJ; 50S ribosomal protein L36 K02919 RP-L36; large subunit ribosomal protein L36
D RF_RNA14 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D RF_RNA12 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D RF_RNA13 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
C 00970 Aminoacyl-tRNA biosynthesis [PATH:rfe00970]
D RF_RNA21 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D RF_RNA27 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D RF_RNA36 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D RF_RNA24 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D RF_RNA26 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D RF_RNA31 tRNA-Asn K14220 tRNA-Asn; tRNA Asn
D RF_RNA18 tRNA-Asp K14221 tRNA-Asp; tRNA Asp
D RF_RNA15 tRNA-Cys K14222 tRNA-Cys; tRNA Cys
D RF_RNA25 tRNA-Gln K14223 tRNA-Gln; tRNA Gln
D RF_RNA02 tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D RF_RNA10 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D RF_RNA29 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D RF_RNA07 tRNA-His K14226 tRNA-His; tRNA His
D RF_RNA17 tRNA-Ile K14227 tRNA-Ile; tRNA Ile
D RF_RNA08 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D RF_RNA38 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D RF_RNA28 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D RF_RNA16 tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D RF_RNA30 tRNA-Met K14230 tRNA-Met; tRNA Met
D RF_RNA04 tRNA-Met K14230 tRNA-Met; tRNA Met
D RF_RNA34 tRNA-Met K14230 tRNA-Met; tRNA Met
D RF_RNA01 tRNA-Phe K14231 tRNA-Phe; tRNA Phe
D RF_RNA35 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D RF_RNA23 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D RF_RNA22 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D RF_RNA05 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D RF_RNA32 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D RF_RNA39 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D RF_RNA03 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D RF_RNA33 tRNA-Trp K14235 tRNA-Trp; tRNA Trp
D RF_RNA09 tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr
D RF_RNA20 tRNA-Val K14237 tRNA-Val; tRNA Val
D RF_RNA11 tRNA-Val K14237 tRNA-Val; tRNA Val
D RF_0413 gltX2; Glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D RF_0529 gltX1; Glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D RF_1129 gatA; Glutamyl-tRNA(Gln) amidotransferase subunit A K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7]
D RF_1130 gatB; Glutamyl-tRNA(Gln) amidotransferase subunit B K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7]
D RF_1128 gatC; Glutamyl-tRNA(Gln) amidotransferase subunit C K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7]
D RF_1353 alaS; Alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D RF_1138 aspS; Aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D RF_1347 glyQ; Glycyl-tRNA synthetase alpha chain K01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14]
D RF_1346 glyS; Glycyl-tRNA synthetase beta chain K01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14]
D RF_0979 thrS; Threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D RF_1249 serS; Seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D RF_0068 cysS; Cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D RF_0235 metG; Methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D RF_0325 fmt; Methionyl-tRNA formyltransferase K00604 MTFMT; methionyl-tRNA formyltransferase [EC:2.1.2.9]
D RF_0229 valS; Valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D RF_0651 leuS; Leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D RF_0423 ileS; Isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D RF_0582 lysS; Lysyl-tRNA synthetase K04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6]
D RF_0109 argS; Arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D RF_0600 proS; Prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D RF_0498 hisS; Histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D RF_0647 pheS; Phenylalanyl-tRNA synthetase alpha chain K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D RF_0648 pheT; Phenylalanyl-tRNA synthetase beta chain K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D RF_0877 tyrS; Tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D RF_0824 trpS; Tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
C 03013 Nucleocytoplasmic transport
C 03015 mRNA surveillance pathway
C 03008 Ribosome biogenesis in eukaryotes
B
B 09123 Folding, sorting and degradation
C 03060 Protein export [PATH:rfe03060]
D RF_0298 secY; Preprotein translocase SecY subunit K03076 secY; preprotein translocase subunit SecY
D RF_1152 secE; Preprotein translocase SecE subunit K03073 secE; preprotein translocase subunit SecE
D RF_0104 secG; Protein-export membrane protein SecG K03075 secG; preprotein translocase subunit SecG
D RF_0959 secD; Protein-export membrane protein SecD K03072 secD; preprotein translocase subunit SecD
D RF_1179 secF; Protein-export membrane protein secF K03074 secF; preprotein translocase subunit SecF
D RF_0958 yajC; Preprotein translocase YajC subunit K03210 yajC; preprotein translocase subunit YajC
D RF_0131 yidC; Preprotein translocase subunit YidC K03217 yidC; YidC/Oxa1 family membrane protein insertase
D RF_0941 secA; Preprotein translocase SecA subunit K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]
D RF_0055 secB; Protein-export protein SecB K03071 secB; preprotein translocase subunit SecB
D RF_1106 ffh; Signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
D RF_RNA37 signal recognition particle RNA (4.5S RNA) K01983 ffs; SRP RNA
D RF_1238 ftsY; Signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor
D RF_1196 tatA; Twin-arginine translocation protein K03116 tatA; sec-independent protein translocase protein TatA
D RF_1248 tatC; Sec-independent protein translocase protein TatC K03118 tatC; sec-independent protein translocase protein TatC
D RF_1177 lepB; Signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89]
D RF_0632 lspA; Lipoprotein signal peptidase K03101 lspA; signal peptidase II [EC:3.4.23.36]
C 04141 Protein processing in endoplasmic reticulum
C 04130 SNARE interactions in vesicular transport
C 04120 Ubiquitin mediated proteolysis
C 04122 Sulfur relay system [PATH:rfe04122]
D RF_0845 iscS; Cysteine desulfurase IscS K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D RF_0846 spl1; Nifs protein homolog K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D RF_0496 trmU; tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]
C 03050 Proteasome
C 03018 RNA degradation [PATH:rfe03018]
D RF_1051 nudH; (Di)nucleoside polyphosphate hydrolase K08311 nudH; putative (di)nucleoside polyphosphate hydrolase [EC:3.6.1.-]
D RF_1025 rne; Ribonuclease E K08300 rne; ribonuclease E [EC:3.1.26.12]
D RF_0721 pnp; Polyribonucleotide nucleotidyltransferase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
D RF_0264 ATP-dependent RNA helicase RhlE K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7]
D RF_0765 rho; Transcription termination factor K03628 rho; transcription termination factor Rho
D RF_0676 Conserved hypothetical protein K12574 rnj; ribonuclease J [EC:3.1.-.-]
D RF_1084 dnaK; DnaK protein K04043 dnaK; molecular chaperone DnaK
D RF_0409 groEL; 60 kDa chaperonin K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D RF_0019 pcnB; Poly(A) polymerase K00970 pcnB; poly(A) polymerase [EC:2.7.7.19]
B
B 09124 Replication and repair
C 03030 DNA replication [PATH:rfe03030]
D RF_0176 dnaQ; DNA polymerase III epsilon chain K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
D RF_p34 DNA polymerase III, epsilon subunit-like protein K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
D RF_p53 DNA polymerase III, epsilon subunit-like protein K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
D RF_pd53 DNA polymerase III, epsilon subunit-like protein K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
D RF_1244 dnaE; DNA polymerase III alpha chain K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
D RF_1364 dnaX; DNA polymerase III gamma and tau chains K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D RF_1107 holB; DNA polymerase III delta subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
D RF_1078 holA; DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
D RF_1375 unknown K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
D RF_0649 dnaN; DNA polymerase III beta chain K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
D RF_0860 dnaB; Replicative DNA helicase K02314 dnaB; replicative DNA helicase [EC:5.6.2.3]
D RF_1358 dnaG; DNA primase K02316 dnaG; DNA primase [EC:2.7.7.101]
D RF_1325 ssb; Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D RF_0180 rnhA; Ribonuclease H K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D RF_1061 rnhB; Ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4]
D RF_0192 ligA; DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
C 03410 Base excision repair [PATH:rfe03410]
D RF_1191 nth; Endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D RF_0560 mpg; DNA-3-methyladenine glycosidase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
D RF_0242 mutM; Formamidopyrimidine-DNA glycosidase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
D RF_1340 Uracil-DNA glycosylase, family 4 K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
D RF_0250 xth2; Exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D RF_1021 xth1; Exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D RF_0763 recJ; Single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D RF_0192 ligA; DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
C 03420 Nucleotide excision repair [PATH:rfe03420]
D RF_0367 mfd; Transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
D RF_1324 uvrA; Excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
D RF_1060 uvrB; Excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
D RF_0912 uvrC; Excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C
D RF_0687 uvrD; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D RF_0192 ligA; DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
C 03430 Mismatch repair [PATH:rfe03430]
D RF_0483 mutS; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
D RF_1387 mutL; DNA mismatch repair protein MutL K03572 mutL; DNA mismatch repair protein MutL
D RF_0687 uvrD; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D RF_0253 xseA; Exodeoxyribonuclease VII, large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
D RF_0557 xseB; Exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D RF_0763 recJ; Single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D RF_1325 ssb; Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D RF_1244 dnaE; DNA polymerase III alpha chain K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
D RF_0649 dnaN; DNA polymerase III beta chain K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
D RF_1364 dnaX; DNA polymerase III gamma and tau chains K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D RF_1078 holA; DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
D RF_1107 holB; DNA polymerase III delta subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
D RF_0176 dnaQ; DNA polymerase III epsilon chain K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
D RF_p34 DNA polymerase III, epsilon subunit-like protein K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
D RF_p53 DNA polymerase III, epsilon subunit-like protein K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
D RF_pd53 DNA polymerase III, epsilon subunit-like protein K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
D RF_1375 unknown K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
D RF_0192 ligA; DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D RF_0123 dam; Site-specific DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
C 03440 Homologous recombination [PATH:rfe03440]
D RF_0763 recJ; Single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D RF_1325 ssb; Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D RF_0035 recF; DNA replication and repair protein RecF K03629 recF; DNA replication and repair protein RecF
D RF_0868 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
D RF_0672 recR; Recombination protein RecR K06187 recR; recombination protein RecR
D RF_1221 recA; RecA protein K03553 recA; recombination protein RecA
D RF_0604 ruvA; Holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
D RF_0606 ruvB; Holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
D RF_1173 ruvC; Crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D RF_0378 recG; ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
D RF_1244 dnaE; DNA polymerase III alpha chain K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
D RF_0649 dnaN; DNA polymerase III beta chain K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
D RF_1364 dnaX; DNA polymerase III gamma and tau chains K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D RF_1078 holA; DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
D RF_1107 holB; DNA polymerase III delta subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
D RF_0176 dnaQ; DNA polymerase III epsilon chain K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
D RF_p34 DNA polymerase III, epsilon subunit-like protein K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
D RF_p53 DNA polymerase III, epsilon subunit-like protein K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
D RF_pd53 DNA polymerase III, epsilon subunit-like protein K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
D RF_1375 unknown K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
D RF_0858 priA; Primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
C 03450 Non-homologous end-joining
C 03460 Fanconi anemia pathway
B
B 09126 Chromosome
C 03082 ATP-dependent chromatin remodeling
C 03083 Polycomb repressive complex
B
B 09125 Information processing in viruses
C 03230 Viral genome structure
C 03240 Viral replication
C 03250 Viral life cycle - HIV-1
C 03260 Virion - Human immunodeficiency virus
C 03271 Virion - Rotavirus
C 03262 Virion - Coronavirus
C 03261 Virion - Influenza virus
C 03263 Virion - Enterovirus
C 03264 Virion - Flavivirus
C 03265 Virion - Ebolavirus and Lyssavirus
C 03266 Virion - Herpesvirus
C 03268 Virion - Orthopoxvirus
C 03267 Virion - Adenovirus
C 03259 Virion - Bacteriophages T4 and T7
C 03258 Virion - Bacteriophage lambda
#
A09130 Environmental Information Processing
B
B 09131 Membrane transport
C 02010 ABC transporters [PATH:rfe02010]
D RF_0077 unknown K07323 mlaC; phospholipid transport system substrate-binding protein
D RF_0182 ABC transporter substrate binding protein K02067 mlaD; phospholipid/cholesterol/gamma-HCH transport system substrate-binding protein
D RF_0080 ABC transporter permease protein K02066 mlaE; phospholipid/cholesterol/gamma-HCH transport system permease protein
D RF_0081 mkl; Ribonucleotide ABC transporter ATP-binding protein K02065 mlaF; phospholipid/cholesterol/gamma-HCH transport system ATP-binding protein
D RF_0018 znuA; Zinc/manganese ABC transporter substrate binding protein K09815 znuA; zinc transport system substrate-binding protein
D RF_0415 znuB; Zinc/manganese ABC transporter permease protein K09816 znuB; zinc transport system permease protein
D RF_1323 znuC; Zinc ABC transporter ATP-binding protein K09817 znuC; zinc transport system ATP-binding protein [EC:7.2.2.20]
D RF_0526 bioY1; BioY family protein K03523 bioY; biotin transport system substrate-specific component
D RF_0739 bioY2; BioY family protein K03523 bioY; biotin transport system substrate-specific component
D RF_0004 rfbA; O-antigen export system permease protein RfbA K09690 wzm; homopolymeric O-antigen transport system permease protein
D RF_0003 rfbE; O-antigen export system ATP-binding protein RfbE K09691 wzt; homopolymeric O-antigen transport system ATP-binding protein [EC:7.5.2.14]
D RF_0211 Lipoprotein releasing system, transmembrane protein K09808 lolC_E; lipoprotein-releasing system permease protein
D RF_0210 lolD; Lipoprotein releasing system ATP-binding protein LolD K09810 lolD; lipoprotein-releasing system ATP-binding protein [EC:7.6.2.-]
D RF_1318 ccmC; Heme exporter protein C K02195 ccmC; heme exporter protein C
D RF_1012 ccmB; Heme exporter protein B K02194 ccmB; heme exporter protein B
D RF_1259 ccmA; Heme exporter protein A K02193 ccmA; heme exporter protein A [EC:7.6.2.5]
D RF_1374 Predicted permeases K07091 lptF; lipopolysaccharide export system permease protein
D RF_1233 Predicted permeases K11720 lptG; lipopolysaccharide export system permease protein
D RF_0717 abcT2; ABC transporter ATP-binding protein K06861 lptB; lipopolysaccharide export system ATP-binding protein [EC:7.5.2.5]
D RF_0607 msbA1; Multidrug resistance protein K11085 msbA; ATP-binding cassette, subfamily B, bacterial MsbA [EC:7.5.2.6]
D RF_1057 atm1; Multidrug resistance protein Atm1 K24821 atm1; ATP-binding cassette, subfamily B, heavy metal transporter
D RF_0511 aprD; Alkaline protease secretion ATP-binding protein AprD K12536 hasD; ATP-binding cassette, subfamily C, type I secretion system permease/ATPase
C 02060 Phosphotransferase system (PTS)
C 03070 Bacterial secretion system [PATH:rfe03070]
D RF_0985 tolC; Type I secretion outer membrane protein, TolC family K12340 tolC; outer membrane protein
D RF_0959 secD; Protein-export membrane protein SecD K03072 secD; preprotein translocase subunit SecD
D RF_1179 secF; Protein-export membrane protein secF K03074 secF; preprotein translocase subunit SecF
D RF_1152 secE; Preprotein translocase SecE subunit K03073 secE; preprotein translocase subunit SecE
D RF_0104 secG; Protein-export membrane protein SecG K03075 secG; preprotein translocase subunit SecG
D RF_0298 secY; Preprotein translocase SecY subunit K03076 secY; preprotein translocase subunit SecY
D RF_0958 yajC; Preprotein translocase YajC subunit K03210 yajC; preprotein translocase subunit YajC
D RF_0131 yidC; Preprotein translocase subunit YidC K03217 yidC; YidC/Oxa1 family membrane protein insertase
D RF_0941 secA; Preprotein translocase SecA subunit K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]
D RF_1238 ftsY; Signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor
D RF_0055 secB; Protein-export protein SecB K03071 secB; preprotein translocase subunit SecB
D RF_1106 ffh; Signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
D RF_1196 tatA; Twin-arginine translocation protein K03116 tatA; sec-independent protein translocase protein TatA
D RF_1248 tatC; Sec-independent protein translocase protein TatC K03118 tatC; sec-independent protein translocase protein TatC
D RF_0087 virB3; Type IV secretory pathway, VirB3-like protein K03198 virB3; type IV secretion system protein VirB3
D RF_0462 virB9_1; VirB9 protein K03204 virB9; type IV secretion system protein VirB9
D RF_0466 virB9_2; VirB9 protein precursor K03204 virB9; type IV secretion system protein VirB9
D RF_0089 virB6_1; TrbL/VirB6 plasmid Conjugative transfer protein K03201 virB6; type IV secretion system protein VirB6
D RF_0090 virB6_2; TrbL/VirB6 plasmid Conjugative transfer protein K03201 virB6; type IV secretion system protein VirB6
D RF_0092 virB6_4; TrbL/VirB6 plasmid Conjugative transfer protein K03201 virB6; type IV secretion system protein VirB6
D RF_0093 virB6_5; TrbL/VirB6 plasmid Conjugative transfer protein K03201 virB6; type IV secretion system protein VirB6
D RF_0091 virB6_3; TrbL/VirB6 plasmid Conjugative transfer protein K03201 virB6; type IV secretion system protein VirB6
D RF_0463 virB8_1; VirB8 protein K03203 virB8; type IV secretion system protein VirB8
D RF_0465 virB8_2; VirB8 protein K03203 virB8; type IV secretion system protein VirB8
D RF_0467 virB10; VirB10 protein K03195 virB10; type IV secretion system protein VirB10
D RF_0088 virB4_1; Type IV secretion/conjugal transfer ATPase, VirB4 family K03199 virB4; type IV secretion system protein VirB4 [EC:7.4.2.8]
D RF_1250 virB4_2; Type IV secretion/conjugal transfer ATPase, VirB4 family K03199 virB4; type IV secretion system protein VirB4 [EC:7.4.2.8]
D RF_0468 virB11; VirB11 protein K03196 virB11; type IV secretion system protein VirB11 [EC:7.4.2.8]
D RF_0469 virD4; VirD4 protein K03205 virD4; type IV secretion system protein VirD4 [EC:7.4.2.8]
B
B 09132 Signal transduction
C 02020 Two-component system [PATH:rfe02020]
D RF_0657 envZ; Osmolarity sensor protein EnvZ K07638 envZ; two-component system, OmpR family, osmolarity sensor histidine kinase EnvZ [EC:2.7.13.3]
D RF_0658 ompR; PetR protein K07659 ompR; two-component system, OmpR family, phosphate regulon response regulator OmpR
D RF_1166 htrA; Periplasmic serine protease K04771 degP; serine protease Do [EC:3.4.21.107]
D RF_0642 mfp; Membrane-fusion protein component of the RND family transporter K07799 mdtA; membrane fusion protein, multidrug efflux system
D RF_1024 coxW; Cytochrome c oxidase assembly protein K02259 COX15; heme a synthase [EC:1.17.99.9]
D RF_0364 dnaA; Chromosomal replication initiator protein DnaA K02313 dnaA; chromosomal replication initiator protein
D RF_0996 D-alanyl-D-alanine dipeptidase K08641 vanX; zinc D-Ala-D-Ala dipeptidase [EC:3.4.13.22]
D RF_1367 ampC; Beta-lactamase AmpC (Class C) K01467 ampC; beta-lactamase class C [EC:3.5.2.6]
D RF_0707 unknown K27078 cupE; spore coat protein U domain-containing protein, fimbrial subunit CupE1/2/3/6
D RF_0703 unknown K27078 cupE; spore coat protein U domain-containing protein, fimbrial subunit CupE1/2/3/6
D RF_0704 unknown K07346 fimC; fimbrial chaperone protein
D RF_0705 P pilus assembly protein FimD K07347 fimD; outer membrane usher protein
D RF_0706 P pilus assembly protein FimD K07347 fimD; outer membrane usher protein
D RF_0728 glnA; Glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D RF_0427 ntrY; Nitrogen regulation protein NtrY K13598 ntrY; two-component system, NtrC family, nitrogen regulation sensor histidine kinase NtrY [EC:2.7.13.3]
D RF_0895 ntrX; Nitrogen assimilation regulatory protein NtrX K13599 ntrX; two-component system, NtrC family, nitrogen regulation response regulator NtrX
D RF_0163 paaJ; Acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D RF_0990 barA; Histidine kinase sensor protein K07716 pleC; two-component system, cell cycle sensor histidine kinase PleC [EC:2.7.13.3]
D RF_1050 Regulatory components of sensory transduction system K02488 pleD; two-component system, cell cycle response regulator [EC:2.7.7.65]
D RF_0056 czcR; Transcriptional activator protein CzcR K13584 ctrA; two-component system, cell cycle response regulator CtrA
D RF_1010 petA; Ubiquinol-cytochrome c reductase, iron-sulfur subunit K00411 UQCRFS1; ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:7.1.1.8]
D RF_1009 petB; Cytochrome b K00412 CYTB; ubiquinol-cytochrome c reductase cytochrome b subunit
D RF_1007 fbcH; Cytochrome c1, heme protein precursor K00413 CYC1; ubiquinol-cytochrome c reductase cytochrome c1 subunit
D RF_1030 cycM; Cytochrome c K08738 CYC; cytochrome c
D RF_0333 cydA; Cytochrome d ubiquinol oxidase subunit I K00425 cydA; cytochrome bd ubiquinol oxidase subunit I [EC:7.1.1.7]
D RF_0336 cydB; Cytochrome d ubiquinol oxidase subunit II K00426 cydB; cytochrome bd ubiquinol oxidase subunit II [EC:7.1.1.7]
D RF_0985 tolC; Type I secretion outer membrane protein, TolC family K12340 tolC; outer membrane protein
D RF_0540 rffE; UDP-N-acetylglucosamine 2-epimerase K01791 wecB; UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing) [EC:5.1.3.14]
C 04010 MAPK signaling pathway
C 04013 MAPK signaling pathway - fly
C 04016 MAPK signaling pathway - plant
C 04011 MAPK signaling pathway - yeast
C 04012 ErbB signaling pathway
C 04014 Ras signaling pathway
C 04015 Rap1 signaling pathway
C 04310 Wnt signaling pathway
C 04330 Notch signaling pathway
C 04340 Hedgehog signaling pathway
C 04341 Hedgehog signaling pathway - fly
C 04350 TGF-beta signaling pathway
C 04390 Hippo signaling pathway
C 04391 Hippo signaling pathway - fly
C 04392 Hippo signaling pathway - multiple species
C 04370 VEGF signaling pathway
C 04371 Apelin signaling pathway
C 04630 JAK-STAT signaling pathway
C 04064 NF-kappa B signaling pathway
C 04668 TNF signaling pathway
C 04066 HIF-1 signaling pathway
C 04068 FoxO signaling pathway
C 04020 Calcium signaling pathway
C 04070 Phosphatidylinositol signaling system
C 04072 Phospholipase D signaling pathway
C 04071 Sphingolipid signaling pathway
C 04024 cAMP signaling pathway
C 04022 cGMP-PKG signaling pathway
C 04151 PI3K-Akt signaling pathway
C 04152 AMPK signaling pathway
C 04150 mTOR signaling pathway
C 04075 Plant hormone signal transduction
B
B 09133 Signaling molecules and interaction
C 04080 Neuroactive ligand-receptor interaction
C 04060 Cytokine-cytokine receptor interaction
C 04061 Viral protein interaction with cytokine and cytokine receptor
C 04512 ECM-receptor interaction
C 04514 Cell adhesion molecules
#
A09140 Cellular Processes
B
B 09141 Transport and catabolism
C 04144 Endocytosis
C 04145 Phagosome
C 04142 Lysosome
C 04146 Peroxisome
C 04140 Autophagy - animal
C 04138 Autophagy - yeast
C 04136 Autophagy - other
C 04137 Mitophagy - animal
C 04139 Mitophagy - yeast
C 04148 Efferocytosis
D RF_1010 petA; Ubiquinol-cytochrome c reductase, iron-sulfur subunit K00411 UQCRFS1; ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:7.1.1.8]
B
B 09143 Cell growth and death
C 04110 Cell cycle
C 04111 Cell cycle - yeast
C 04112 Cell cycle - Caulobacter
C 04113 Meiosis - yeast
C 04114 Oocyte meiosis
C 04210 Apoptosis
C 04214 Apoptosis - fly
C 04215 Apoptosis - multiple species
C 04216 Ferroptosis
C 04217 Necroptosis
C 04115 p53 signaling pathway
C 04218 Cellular senescence
B
B 09144 Cellular community - eukaryotes
C 04510 Focal adhesion
C 04520 Adherens junction
C 04530 Tight junction
C 04540 Gap junction
C 04550 Signaling pathways regulating pluripotency of stem cells
B
B 09145 Cellular community - prokaryotes
C 02024 Quorum sensing [PATH:rfe02024]
D RF_0643 RND efflux system, outer membrane protein K18139 oprM; outer membrane protein, multidrug efflux system
D RF_0131 yidC; Preprotein translocase subunit YidC K03217 yidC; YidC/Oxa1 family membrane protein insertase
D RF_1152 secE; Preprotein translocase SecE subunit K03073 secE; preprotein translocase subunit SecE
D RF_0104 secG; Protein-export membrane protein SecG K03075 secG; preprotein translocase subunit SecG
D RF_0298 secY; Preprotein translocase SecY subunit K03076 secY; preprotein translocase subunit SecY
D RF_0958 yajC; Preprotein translocase YajC subunit K03210 yajC; preprotein translocase subunit YajC
D RF_0941 secA; Preprotein translocase SecA subunit K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]
D RF_1238 ftsY; Signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor
D RF_0055 secB; Protein-export protein SecB K03071 secB; preprotein translocase subunit SecB
D RF_1106 ffh; Signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
C 05111 Biofilm formation - Vibrio cholerae
C 02025 Biofilm formation - Pseudomonas aeruginosa
C 02026 Biofilm formation - Escherichia coli
B
B 09142 Cell motility
C 02030 Bacterial chemotaxis
C 02040 Flagellar assembly
D RF_1357 rpoD; RNA polymerase sigma factor K03086 rpoD; RNA polymerase primary sigma factor
C 04814 Motor proteins
C 04820 Cytoskeleton in muscle cells
C 04810 Regulation of actin cytoskeleton
#
A09150 Organismal Systems
B
B 09151 Immune system
C 04640 Hematopoietic cell lineage
C 04610 Complement and coagulation cascades
C 04611 Platelet activation
C 04613 Neutrophil extracellular trap formation
C 04620 Toll-like receptor signaling pathway
C 04624 Toll and Imd signaling pathway
C 04621 NOD-like receptor signaling pathway
C 04622 RIG-I-like receptor signaling pathway
C 04623 Cytosolic DNA-sensing pathway
C 04625 C-type lectin receptor signaling pathway
C 04650 Natural killer cell mediated cytotoxicity
C 04612 Antigen processing and presentation
C 04660 T cell receptor signaling pathway
C 04658 Th1 and Th2 cell differentiation
C 04659 Th17 cell differentiation
C 04657 IL-17 signaling pathway
C 04662 B cell receptor signaling pathway
C 04664 Fc epsilon RI signaling pathway
C 04666 Fc gamma R-mediated phagocytosis
C 04670 Leukocyte transendothelial migration
C 04672 Intestinal immune network for IgA production
C 04062 Chemokine signaling pathway
B
B 09152 Endocrine system
C 04911 Insulin secretion
C 04910 Insulin signaling pathway
C 04922 Glucagon signaling pathway
C 04923 Regulation of lipolysis in adipocytes
C 04920 Adipocytokine signaling pathway
C 03320 PPAR signaling pathway
C 04929 GnRH secretion
C 04912 GnRH signaling pathway
C 04913 Ovarian steroidogenesis
C 04915 Estrogen signaling pathway
C 04914 Progesterone-mediated oocyte maturation
C 04917 Prolactin signaling pathway
C 04921 Oxytocin signaling pathway
C 04926 Relaxin signaling pathway
C 04935 Growth hormone synthesis, secretion and action
C 04918 Thyroid hormone synthesis
C 04919 Thyroid hormone signaling pathway
C 04928 Parathyroid hormone synthesis, secretion and action
C 04916 Melanogenesis
C 04924 Renin secretion
C 04614 Renin-angiotensin system
C 04925 Aldosterone synthesis and secretion
C 04927 Cortisol synthesis and secretion
B
B 09153 Circulatory system
C 04260 Cardiac muscle contraction
C 04261 Adrenergic signaling in cardiomyocytes
C 04270 Vascular smooth muscle contraction
B
B 09154 Digestive system
C 04970 Salivary secretion
C 04971 Gastric acid secretion
C 04972 Pancreatic secretion
C 04976 Bile secretion
C 04973 Carbohydrate digestion and absorption
C 04974 Protein digestion and absorption
C 04975 Fat digestion and absorption
C 04979 Cholesterol metabolism
C 04977 Vitamin digestion and absorption
C 04980 Cobalamin transport and metabolism
C 04978 Mineral absorption
B
B 09155 Excretory system
C 04962 Vasopressin-regulated water reabsorption
C 04960 Aldosterone-regulated sodium reabsorption
C 04961 Endocrine and other factor-regulated calcium reabsorption
C 04964 Proximal tubule bicarbonate reclamation
C 04966 Collecting duct acid secretion
B
B 09156 Nervous system
C 04724 Glutamatergic synapse
C 04727 GABAergic synapse
C 04725 Cholinergic synapse
C 04728 Dopaminergic synapse
C 04726 Serotonergic synapse
C 04720 Long-term potentiation
C 04730 Long-term depression
C 04723 Retrograde endocannabinoid signaling
C 04721 Synaptic vesicle cycle
C 04722 Neurotrophin signaling pathway
B
B 09157 Sensory system
C 04744 Phototransduction
C 04745 Phototransduction - fly
C 04740 Olfactory transduction
C 04742 Taste transduction
C 04750 Inflammatory mediator regulation of TRP channels
B
B 09158 Development and regeneration
C 04320 Dorso-ventral axis formation
C 04360 Axon guidance
C 04361 Axon regeneration
C 04380 Osteoclast differentiation
B
B 09149 Aging
C 04211 Longevity regulating pathway
C 04212 Longevity regulating pathway - worm
C 04213 Longevity regulating pathway - multiple species
B
B 09159 Environmental adaptation
C 04710 Circadian rhythm
C 04713 Circadian entrainment
C 04711 Circadian rhythm - fly
C 04712 Circadian rhythm - plant
C 04714 Thermogenesis
C 04626 Plant-pathogen interaction
#
A09160 Human Diseases
B
B 09161 Cancer: overview
C 05200 Pathways in cancer
C 05202 Transcriptional misregulation in cancer
C 05206 MicroRNAs in cancer
C 05205 Proteoglycans in cancer
C 05204 Chemical carcinogenesis - DNA adducts
C 05207 Chemical carcinogenesis - receptor activation
C 05208 Chemical carcinogenesis - reactive oxygen species
C 05203 Viral carcinogenesis
C 05230 Central carbon metabolism in cancer
C 05231 Choline metabolism in cancer
C 05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
B
B 09162 Cancer: specific types
C 05210 Colorectal cancer
C 05212 Pancreatic cancer
C 05225 Hepatocellular carcinoma
C 05226 Gastric cancer
C 05214 Glioma
C 05216 Thyroid cancer
C 05221 Acute myeloid leukemia
C 05220 Chronic myeloid leukemia
C 05217 Basal cell carcinoma
C 05218 Melanoma
C 05211 Renal cell carcinoma
C 05219 Bladder cancer
C 05215 Prostate cancer
C 05213 Endometrial cancer
C 05224 Breast cancer
C 05222 Small cell lung cancer
C 05223 Non-small cell lung cancer
B
B 09172 Infectious disease: viral
C 05166 Human T-cell leukemia virus 1 infection
C 05170 Human immunodeficiency virus 1 infection
C 05161 Hepatitis B
C 05160 Hepatitis C
C 05171 Coronavirus disease - COVID-19
C 05164 Influenza A
C 05162 Measles
C 05168 Herpes simplex virus 1 infection
C 05163 Human cytomegalovirus infection
C 05167 Kaposi sarcoma-associated herpesvirus infection
C 05169 Epstein-Barr virus infection
C 05165 Human papillomavirus infection
B
B 09171 Infectious disease: bacterial
C 05110 Vibrio cholerae infection
C 05120 Epithelial cell signaling in Helicobacter pylori infection
C 05130 Pathogenic Escherichia coli infection
C 05132 Salmonella infection
C 05131 Shigellosis
C 05135 Yersinia infection
C 05133 Pertussis
C 05134 Legionellosis
C 05150 Staphylococcus aureus infection
C 05152 Tuberculosis
C 05100 Bacterial invasion of epithelial cells
B
B 09174 Infectious disease: parasitic
C 05146 Amoebiasis
C 05144 Malaria
C 05145 Toxoplasmosis
C 05140 Leishmaniasis
C 05142 Chagas disease
C 05143 African trypanosomiasis
B
B 09163 Immune disease
C 05310 Asthma
C 05322 Systemic lupus erythematosus
C 05323 Rheumatoid arthritis
C 05320 Autoimmune thyroid disease
C 05321 Inflammatory bowel disease
C 05330 Allograft rejection
C 05332 Graft-versus-host disease
C 05340 Primary immunodeficiency
B
B 09164 Neurodegenerative disease
C 05010 Alzheimer disease
C 05012 Parkinson disease
C 05014 Amyotrophic lateral sclerosis
C 05016 Huntington disease
C 05017 Spinocerebellar ataxia
C 05020 Prion disease
C 05022 Pathways of neurodegeneration - multiple diseases
B
B 09165 Substance dependence
C 05030 Cocaine addiction
C 05031 Amphetamine addiction
C 05032 Morphine addiction
C 05033 Nicotine addiction
C 05034 Alcoholism
B
B 09166 Cardiovascular disease
C 05417 Lipid and atherosclerosis
C 05418 Fluid shear stress and atherosclerosis
C 05410 Hypertrophic cardiomyopathy
C 05412 Arrhythmogenic right ventricular cardiomyopathy
C 05414 Dilated cardiomyopathy
C 05415 Diabetic cardiomyopathy
C 05416 Viral myocarditis
B
B 09167 Endocrine and metabolic disease
C 04930 Type II diabetes mellitus
C 04940 Type I diabetes mellitus
C 04950 Maturity onset diabetes of the young
C 04936 Alcoholic liver disease
C 04932 Non-alcoholic fatty liver disease
C 04931 Insulin resistance
C 04933 AGE-RAGE signaling pathway in diabetic complications
C 04934 Cushing syndrome
B
B 09175 Drug resistance: antimicrobial
C 01501 beta-Lactam resistance [PATH:rfe01501]
D RF_0608 ampG4; AmpG protein K08218 ampG; MFS transporter, PAT family, beta-lactamase induction signal transducer AmpG
D RF_0834 ampG1; AmpG-related permease K08218 ampG; MFS transporter, PAT family, beta-lactamase induction signal transducer AmpG
D RF_1367 ampC; Beta-lactamase AmpC (Class C) K01467 ampC; beta-lactamase class C [EC:3.5.2.6]
D RF_0643 RND efflux system, outer membrane protein K18139 oprM; outer membrane protein, multidrug efflux system
D RF_0985 tolC; Type I secretion outer membrane protein, TolC family K12340 tolC; outer membrane protein
D RF_1276 mrcA; Penicillin-binding protein 1A family K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]
D RF_0900 pbpA1; Penicillin-binding protein K05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4]
D RF_0902 pbpA2; Penicillin-binding protein K03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4]
D RF_1275 blaD; Beta-lactamase Class D K17838 oxa; beta-lactamase class D [EC:3.5.2.6]
C 01502 Vancomycin resistance [PATH:rfe01502]
D RF_0996 D-alanyl-D-alanine dipeptidase K08641 vanX; zinc D-Ala-D-Ala dipeptidase [EC:3.4.13.22]
D RF_1035 ddlB; D-alanine--D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]
D RF_0079 alr; Alanine racemase K01775 alr; alanine racemase [EC:5.1.1.1]
D RF_0369 murF; UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]
D RF_0370 mraY1; Phospho-N-acetylmuramoyl-pentapeptide-transferase K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13]
D RF_0636 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]
C 01503 Cationic antimicrobial peptide (CAMP) resistance [PATH:rfe01503]
D RF_1166 htrA; Periplasmic serine protease K04771 degP; serine protease Do [EC:3.4.21.107]
D RF_0985 tolC; Type I secretion outer membrane protein, TolC family K12340 tolC; outer membrane protein
D RF_0006 lpxA; Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase K00677 lpxA; UDP-N-acetylglucosamine acyltransferase [EC:2.3.1.129]
B
B 09176 Drug resistance: antineoplastic
C 01521 EGFR tyrosine kinase inhibitor resistance
C 01524 Platinum drug resistance
C 01523 Antifolate resistance
C 01522 Endocrine resistance
#
A09180 Brite Hierarchies
B
B 09181 Protein families: metabolism
C 01000 Enzymes [BR:rfe01000]
C 01001 Protein kinases [BR:rfe01001]
D RF_0657 envZ; Osmolarity sensor protein EnvZ K07638 envZ; two-component system, OmpR family, osmolarity sensor histidine kinase EnvZ [EC:2.7.13.3]
D RF_0427 ntrY; Nitrogen regulation protein NtrY K13598 ntrY; two-component system, NtrC family, nitrogen regulation sensor histidine kinase NtrY [EC:2.7.13.3]
D RF_0990 barA; Histidine kinase sensor protein K07716 pleC; two-component system, cell cycle sensor histidine kinase PleC [EC:2.7.13.3]
C 01009 Protein phosphatases and associated proteins [BR:rfe01009]
D RF_1333 htpG; Heat shock protein HtpG K04079 HSP90A; molecular chaperone HtpG
C 01002 Peptidases and inhibitors [BR:rfe01002]
D RF_0632 lspA; Lipoprotein signal peptidase K03101 lspA; signal peptidase II [EC:3.4.23.36]
D RF_0626 Predicted glutamine amidotransferases K07010 K07010; putative glutamine amidotransferase
D RF_0507 unknown K07052 K07052; CAAX protease family protein
D RF_0996 D-alanyl-D-alanine dipeptidase K08641 vanX; zinc D-Ala-D-Ala dipeptidase [EC:3.4.13.22]
D RF_1143 pepA; Aminopeptidase A K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1]
D RF_1376 dapE; Succinyl-diaminopimelate desuccinylase K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18]
D RF_1309 map; Methionine aminopeptidase, type I K01265 map; methionyl aminopeptidase [EC:3.4.11.18]
D RF_0840 pepP; Aminopeptidase P K01262 pepP; Xaa-Pro aminopeptidase [EC:3.4.11.9]
D RF_1091 Thermostable carboxypeptidase K01299 E3.4.17.19; carboxypeptidase Taq [EC:3.4.17.19]
D RF_1090 Thermostable carboxypeptidase K01299 E3.4.17.19; carboxypeptidase Taq [EC:3.4.17.19]
D RF_0139 ftsH; ATP-dependent metalloprotease FtsH K03798 ftsH; cell division protease FtsH [EC:3.4.24.-]
D RF_1120 Membrane-associated zinc metalloprotease K11749 rseP; regulator of sigma E protease [EC:3.4.24.-]
D RF_1166 htrA; Periplasmic serine protease K04771 degP; serine protease Do [EC:3.4.21.107]
D RF_1104 Prolyl endopeptidase precursor K01322 PREP; prolyl oligopeptidase [EC:3.4.21.26]
D RF_0454 ptrB; Protease II K01354 ptrB; oligopeptidase B [EC:3.4.21.83]
D RF_0609 dacF; Penicillin-binding protein DacF precursor K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4]
D RF_0772 clpP; ATP-dependent Clp protease proteolytic subunit K01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92]
D RF_0692 lon; ATP-dependent protease La K01338 lon; ATP-dependent Lon protease [EC:3.4.21.53]
D RF_p26 lon; ATP-dependent protease La, bacterial type K01338 lon; ATP-dependent Lon protease [EC:3.4.21.53]
D RF_1177 lepB; Signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89]
D RF_0989 ctp; Carboxyl-terminal protease K03797 E3.4.21.102; carboxyl-terminal processing protease [EC:3.4.21.102]
D RF_0766 sppA2; Signal peptide peptidase SppA K04773 sppA; protease IV [EC:3.4.21.-]
D RF_0515 hslV; Heat shock protein HslV K01419 hslV; ATP-dependent HslUV protease, peptidase subunit HslV [EC:3.4.25.2]
D RF_0268 ecoT; Ecotin precursor K08276 eco; ecotin
D RF_0887 Large extracellular alpha-helical protein K06894 yfhM; alpha-2-macroglobulin
D RF_1167 hflC2; Membrane protease subunits K04087 hflC; modulator of FtsH protease HflC
D RF_1168 hflK; Protease activity modulator HflK K04088 hflK; modulator of FtsH protease HflK
C 01003 Glycosyltransferases [BR:rfe01003]
D RF_1069 pbpC; Bifunctional penicillin-binding protein 1C K05367 pbpC; penicillin-binding protein 1C [EC:2.4.99.28]
D RF_1276 mrcA; Penicillin-binding protein 1A family K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]
C 01005 Lipopolysaccharide biosynthesis proteins [BR:rfe01005]
D RF_0006 lpxA; Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase K00677 lpxA; UDP-N-acetylglucosamine acyltransferase [EC:2.3.1.129]
D RF_0519 lpxB; Lipid-A-disaccharide synthase K00748 lpxB; lipid-A-disaccharide synthase [EC:2.4.1.182]
D RF_1028 lpxC; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase K02535 lpxC; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [EC:3.5.1.108]
D RF_0008 lpxD; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase K02536 lpxD; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase [EC:2.3.1.191]
D RF_0178 unknown K09949 lpxI; UDP-2,3-diacylglucosamine hydrolase [EC:3.6.1.54]
D RF_0196 lpxK; Tetraacyldisaccharide 4'-kinase K00912 lpxK; tetraacyldisaccharide 4'-kinase [EC:2.7.1.130]
D RF_0197 htrB; Lipid A biosynthesis lauroyl acyltransferase K02517 lpxL; Kdo2-lipid IVA lauroyltransferase/acyltransferase [EC:2.3.1.241 2.3.1.-]
D RF_0072 kdtA; 3-deoxy-D-manno-octulosonic-acid transferase K02527 kdtA; 3-deoxy-D-manno-octulosonic-acid transferase [EC:2.4.99.12 2.4.99.13 2.4.99.14 2.4.99.15]
D RF_0113 kdsA; 3-deoxy-8-phosphooctulonate synthase K01627 kdsA; 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase) [EC:2.5.1.55]
D RF_0594 kdsB; 3-deoxy-manno-octulosonate cytidylyltransferase K00979 kdsB; 3-deoxy-manno-octulosonate cytidylyltransferase (CMP-KDO synthetase) [EC:2.7.7.38]
D RF_0720 kpsF; KpsF protein K06041 kdsD; arabinose-5-phosphate isomerase [EC:5.3.1.13]
C 01011 Peptidoglycan biosynthesis and degradation proteins [BR:rfe01011]
D RF_0945 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]
D RF_1036 murB; UDP-N-acetylenolpyruvoylglucosamine reductase K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98]
D RF_1037 murC; UDP-N-acetylmuramate--alanine ligase K01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8]
D RF_0634 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]
D RF_0368 murE; UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase K01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13]
D RF_1035 ddlB; D-alanine--D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]
D RF_0079 alr; Alanine racemase K01775 alr; alanine racemase [EC:5.1.1.1]
D RF_0370 mraY1; Phospho-N-acetylmuramoyl-pentapeptide-transferase K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13]
D RF_0636 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]
D RF_0963 mviN; Integral membrane protein MviN K03980 murJ; putative peptidoglycan lipid II flippase
D RF_1276 mrcA; Penicillin-binding protein 1A family K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]
D RF_1069 pbpC; Bifunctional penicillin-binding protein 1C K05367 pbpC; penicillin-binding protein 1C [EC:2.4.99.28]
D RF_0900 pbpA1; Penicillin-binding protein K05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4]
D RF_0902 pbpA2; Penicillin-binding protein K03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4]
D RF_0609 dacF; Penicillin-binding protein DacF precursor K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4]
D RF_0996 D-alanyl-D-alanine dipeptidase K08641 vanX; zinc D-Ala-D-Ala dipeptidase [EC:3.4.13.22]
D RF_0621 mltE1; Soluble lytic murein transglycosylase precursor K08309 slt; peptidoglycan lytic transglycosylase [EC:4.2.2.29]
D RF_0521 Conserved hypothetical protein K07082 mltG; peptidoglycan lytic transglycosylase G [EC:4.2.2.29]
D RF_0611 rlpA; Rare lipoprotein A precursor K03642 rlpA; peptidoglycan lytic transglycosylase [EC:4.2.2.29]
D RF_1384 ampD; AmpD protein homolog K11066 amiD; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]
C 01004 Lipid biosynthesis proteins [BR:rfe01004]
D RF_0171 fabD; Malonyl CoA-acyl carrier protein transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]
D RF_1235 fabH; 3-oxoacyl-[acyl carrier protein] synthase III K00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180]
D RF_1224 fabF; 3-oxoacyl-[acyl carrier protein] synthase II K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]
D RF_1222 fabG; 3-oxoacyl reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D RF_0007 fabZ; (3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase K02372 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59]
D RF_0575 fabI; Enoyl-[acyl carrier protein] reductase K00208 fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10]
D RF_0145 aco1; Acyl-CoA desaturase 1 K00507 SCD; stearoyl-CoA desaturase (Delta-9 desaturase) [EC:1.14.19.1]
D RF_0825 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]
C 01008 Polyketide biosynthesis proteins
C 01006 Prenyltransferases [BR:rfe01006]
D RF_0839 ispB; Octaprenyl-diphosphate synthase K02523 ispB; octaprenyl-diphosphate synthase [EC:2.5.1.90]
D RF_0656 uppS; Undecaprenyl pyrophosphate synthetase K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31]
D RF_0714 miaA; tRNA delta(2)-isopentenylpyrophosphate transferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
D RF_0231 ubiA; 4-hydroxybenzoate octaprenyltransferase K03179 ubiA; 4-hydroxybenzoate polyprenyltransferase [EC:2.5.1.39]
D RF_0550 cyoB; Protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141]
C 01007 Amino acid related enzymes [BR:rfe01007]
D RF_0582 lysS; Lysyl-tRNA synthetase K04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6]
D RF_0413 gltX2; Glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D RF_0529 gltX1; Glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D RF_0877 tyrS; Tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D RF_0824 trpS; Tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D RF_0068 cysS; Cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D RF_0109 argS; Arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D RF_0235 metG; Methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D RF_0423 ileS; Isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D RF_0229 valS; Valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D RF_0651 leuS; Leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D RF_1138 aspS; Aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D RF_0498 hisS; Histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D RF_1347 glyQ; Glycyl-tRNA synthetase alpha chain K01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14]
D RF_1346 glyS; Glycyl-tRNA synthetase beta chain K01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14]
D RF_1249 serS; Seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D RF_0600 proS; Prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D RF_0979 thrS; Threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D RF_1353 alaS; Alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D RF_0647 pheS; Phenylalanyl-tRNA synthetase alpha chain K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D RF_0648 pheT; Phenylalanyl-tRNA synthetase beta chain K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D RF_0074 aatA; Aspartate aminotransferase A K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D RF_1334 hemA; 5-aminolevulinic acid synthase K00643 E2.3.1.37; 5-aminolevulinate synthase [EC:2.3.1.37]
D RF_0659 ilvE; Branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
C 00199 Cytochrome P450
C 00194 Photosynthesis proteins [BR:rfe00194]
D RF_1265 atpC; ATP synthase epsilon chain K02114 ATPF1E; F-type H+-transporting ATPase subunit epsilon
D RF_1266 atpD; ATP synthase beta chain K02112 ATPF1B; F-type H+/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1]
D RF_1267 atpG; ATP synthase gamma chain K02115 ATPF1G; F-type H+-transporting ATPase subunit gamma
D RF_1268 atpA; ATP synthase alpha chain K02111 ATPF1A; F-type H+/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1]
D RF_1269 atpH; ATP synthase delta chain K02113 ATPF1D; F-type H+-transporting ATPase subunit delta
D RF_0027 atpF; ATP synthase B chain precursor K02109 ATPF0B; F-type H+-transporting ATPase subunit b
D RF_0028 atpX; ATP synthase B chain K02109 ATPF0B; F-type H+-transporting ATPase subunit b
D RF_0029 atpE; ATP synthase C chain K02110 ATPF0C; F-type H+-transporting ATPase subunit c
D RF_0030 atpB; ATP synthase A chain K02108 ATPF0A; F-type H+-transporting ATPase subunit a
D RF_0031 unknown K02116 atpI; ATP synthase protein I
B
B 09182 Protein families: genetic information processing
C 03000 Transcription factors [BR:rfe03000]
D RF_0138 Site-specific DNA methylase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D RF_0137 Site-specific DNA methylase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D RF_0915 Methylated-DNA--protein-cysteine methyltransferase K10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response / methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]
D RF_0847 iscR; Iron-sulfur cluster assembly transcription factor IscR K13643 iscR; Rrf2 family transcriptional regulator, iron-sulfur cluster assembly transcription factor
D RF_0875 Putative transcriptional regulator K13771 nsrR; Rrf2 family transcriptional regulator, nitric oxide-sensitive transcriptional repressor
D RF_0744 birA; Biotin--acetyl-CoA-carboxylase ligase K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]
D RF_0899 Probable antitoxin of toxin-antitoxin system K18918 relB; RHH-type transcriptional regulator, rel operon repressor / antitoxin RelB
D RF_0957 Probable antitoxin of toxin-antitoxin system K18918 relB; RHH-type transcriptional regulator, rel operon repressor / antitoxin RelB
D RF_1039 bolA1; BolA protein homolog K05527 bolA; BolA family transcriptional regulator, general stress-responsive regulator
D RF_0116 ParB-like partition proteins K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein
D RF_p35 parB; ParB-like nuclease domain K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein
D RF_0033 Transcriptional regulator K07736 carD; CarD family transcriptional regulator, regulator of rRNA transcription
D RF_0044 Putative transcriptional regulator K07735 algH; putative transcriptional regulator
D RF_1294 dksA; DnaK suppressor protein homolog K06204 dksA; RNA polymerase-binding transcription factor
D RF_0905 mraZ; MraZ protein K03925 mraZ; transcriptional regulator MraZ
C 03021 Transcription machinery [BR:rfe03021]
D RF_0302 rpoA; DNA-directed RNA polymerase alpha chain K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
D RF_1146 rpoB; DNA-directed RNA polymerase beta chain K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
D RF_1145 rpoC; DNA-directed RNA polymerase beta prime chain K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
D RF_0944 rpoZ; DNA-directed RNA polymerase omega chain K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
D RF_1357 rpoD; RNA polymerase sigma factor K03086 rpoD; RNA polymerase primary sigma factor
D RF_0493 rpoH; RNA polymerase sigma-32 factor K03089 rpoH; RNA polymerase sigma-32 factor
D RF_0872 nusA; N utilization substance protein A, transcription termination factor NusA K02600 nusA; transcription termination/antitermination protein NusA
D RF_1119 nusB; N utilization substance protein B K03625 nusB; transcription antitermination protein NusB
D RF_1151 nusG; Transcription antitermination protein NusG K02601 nusG; transcription termination/antitermination protein NusG
D RF_1294 dksA; DnaK suppressor protein homolog K06204 dksA; RNA polymerase-binding transcription factor
D RF_1360 greA; Transcription elongation factor GreA K03624 greA; transcription elongation factor GreA
D RF_0765 rho; Transcription termination factor K03628 rho; transcription termination factor Rho
C 03019 Messenger RNA biogenesis [BR:rfe03019]
D RF_1025 rne; Ribonuclease E K08300 rne; ribonuclease E [EC:3.1.26.12]
D RF_1176 rnc; Ribonuclease III K03685 rnc; ribonuclease III [EC:3.1.26.3]
D RF_0676 Conserved hypothetical protein K12574 rnj; ribonuclease J [EC:3.1.-.-]
D RF_0264 ATP-dependent RNA helicase RhlE K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7]
D RF_0721 pnp; Polyribonucleotide nucleotidyltransferase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
D RF_0765 rho; Transcription termination factor K03628 rho; transcription termination factor Rho
D RF_1084 dnaK; DnaK protein K04043 dnaK; molecular chaperone DnaK
D RF_0409 groEL; 60 kDa chaperonin K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D RF_0019 pcnB; Poly(A) polymerase K00970 pcnB; poly(A) polymerase [EC:2.7.7.19]
D RF_1051 nudH; (Di)nucleoside polyphosphate hydrolase K08311 nudH; putative (di)nucleoside polyphosphate hydrolase [EC:3.6.1.-]
C 03041 Spliceosome
C 03011 Ribosome [BR:rfe03011]
D RF_0771 rpsA; 30S ribosomal protein S1 K02945 RP-S1; small subunit ribosomal protein S1
D RF_0069 rpsB; 30S ribosomal protein S2 K02967 RP-S2; small subunit ribosomal protein S2
D RF_0284 rpsC; 30S ribosomal protein S3 K02982 RP-S3; small subunit ribosomal protein S3
D RF_0549 rpsD; 30S ribosomal protein S4 K02986 RP-S4; small subunit ribosomal protein S4
D RF_0295 rpsE; 30S ribosomal protein S5 K02988 RP-S5; small subunit ribosomal protein S5
D RF_0143 rpsF; 30S ribosomal protein S6 K02990 RP-S6; small subunit ribosomal protein S6
D RF_1154 rpsG; 30S ribosomal protein S7 K02992 RP-S7; small subunit ribosomal protein S7
D RF_0292 rpsH; 30S ribosomal protein S8 K02994 RP-S8; small subunit ribosomal protein S8
D RF_0995 rpsI; 30S ribosomal protein S9 K02996 RP-S9; small subunit ribosomal protein S9
D RF_0277 rpsJ; 30S ribosomal protein S10 K02946 RP-S10; small subunit ribosomal protein S10
D RF_0301 rpsK; 30S ribosomal protein S11 K02948 RP-S11; small subunit ribosomal protein S11
D RF_1155 rpsL; 30S ribosomal protein S12 K02950 RP-S12; small subunit ribosomal protein S12
D RF_0300 rpsM; 30S ribosomal protein S13 K02952 RP-S13; small subunit ribosomal protein S13
D RF_0291 rpsN; 30S ribosomal protein S14 K02954 RP-S14; small subunit ribosomal protein S14
D RF_0722 rpsO; 30S ribosomal protein S15 K02956 RP-S15; small subunit ribosomal protein S15
D RF_1385 rpsP; 30S ribosomal protein S16 K02959 RP-S16; small subunit ribosomal protein S16
D RF_0287 rpsQ; 30S ribosomal protein S17 K02961 RP-S17; small subunit ribosomal protein S17
D RF_0142 rpsR; 30S ribosomal protein S18 K02963 RP-S18; small subunit ribosomal protein S18
D RF_0282 rpsS; 30S ribosomal protein S19 K02965 RP-S19; small subunit ribosomal protein S19
D RF_0304 rpsT; 30S ribosomal protein S20 K02968 RP-S20; small subunit ribosomal protein S20
D RF_0426 rpsU; 30S ribosomal protein S21 K02970 RP-S21; small subunit ribosomal protein S21
D RF_1149 rplA; 50S ribosomal protein L1 K02863 RP-L1; large subunit ribosomal protein L1
D RF_0281 rplB; 50S ribosomal protein L2 K02886 RP-L2; large subunit ribosomal protein L2
D RF_0278 rplC; 50S ribosomal protein L3 K02906 RP-L3; large subunit ribosomal protein L3
D RF_0279 rplD; 50S ribosomal protein L4 K02926 RP-L4; large subunit ribosomal protein L4
D RF_0290 rplE; 50S ribosomal protein L5 K02931 RP-L5; large subunit ribosomal protein L5
D RF_0293 rplF; 50S ribosomal protein L6 K02933 RP-L6; large subunit ribosomal protein L6
D RF_0141 rplI; 50S ribosomal protein L9 K02939 RP-L9; large subunit ribosomal protein L9
D RF_1148 rplJ; 50S ribosomal protein L10 K02864 RP-L10; large subunit ribosomal protein L10
D RF_1150 rplK; 50S ribosomal protein L11 K02867 RP-L11; large subunit ribosomal protein L11
D RF_1147 rplL; 50S ribosomal protein L7/L12 K02935 RP-L7; large subunit ribosomal protein L7/L12
D RF_0994 rplM; 50S ribosomal protein L13 K02871 RP-L13; large subunit ribosomal protein L13
D RF_0288 rplN; 50S ribosomal protein L14 K02874 RP-L14; large subunit ribosomal protein L14
D RF_0297 rplO; 50S ribosomal protein L15 K02876 RP-L15; large subunit ribosomal protein L15
D RF_0285 rplP; 50S ribosomal protein L16 K02878 RP-L16; large subunit ribosomal protein L16
D RF_0303 rplQ; 50S ribosomal protein L17 K02879 RP-L17; large subunit ribosomal protein L17
D RF_0294 rplR; 50S ribosomal protein L18 K02881 RP-L18; large subunit ribosomal protein L18
D RF_0100 rplS; 50S ribosomal protein L19 K02884 RP-L19; large subunit ribosomal protein L19
D RF_0349 rplT; 50S ribosomal protein L20 K02887 RP-L20; large subunit ribosomal protein L20
D RF_1198 rplU; 50S ribosomal protein L21 K02888 RP-L21; large subunit ribosomal protein L21
D RF_0283 rplV; 50S ribosomal protein L22 K02890 RP-L22; large subunit ribosomal protein L22
D RF_0280 rplW; 50S ribosomal protein L23 K02892 RP-L23; large subunit ribosomal protein L23
D RF_0289 rplX; 50S ribosomal protein L24 K02895 RP-L24; large subunit ribosomal protein L24
D RF_1199 rpmA; 50S ribosomal protein L27 K02899 RP-L27; large subunit ribosomal protein L27
D RF_0083 rpmB; 50S ribosomal protein L28 K02902 RP-L28; large subunit ribosomal protein L28
D RF_0286 rpmC; 50S ribosomal protein L29 K02904 RP-L29; large subunit ribosomal protein L29
D RF_0296 rpmD; 50S ribosomal protein L30 K02907 RP-L30; large subunit ribosomal protein L30
D RF_0084 rpmE; 50S ribosomal protein L31 K02909 RP-L31; large subunit ribosomal protein L31
D RF_1236 rpmF; 50S ribosomal protein L32 K02911 RP-L32; large subunit ribosomal protein L32
D RF_1386 rpmG; 50S ribosomal protein L33 K02913 RP-L33; large subunit ribosomal protein L33
D RF_0348 rpmH; 50S ribosomal protein L34 K02914 RP-L34; large subunit ribosomal protein L34
D RF_0350 rpmI; 50S ribosomal protein L35 K02916 RP-L35; large subunit ribosomal protein L35
D RF_0800 rpmJ; 50S ribosomal protein L36 K02919 RP-L36; large subunit ribosomal protein L36
D RF_0352 rplY; 50S ribosomal protein L25 K02897 RP-L25; large subunit ribosomal protein L25
D RF_RNA13 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D RF_RNA14 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D RF_RNA12 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
C 03009 Ribosome biogenesis [BR:rfe03009]
D RF_1176 rnc; Ribonuclease III K03685 rnc; ribonuclease III [EC:3.1.26.3]
D RF_1174 era; GTP-binding protein Era K03595 era; GTPase
D RF_1337 obg; GTP-binding protein K03979 obgE; GTPase [EC:3.6.5.-]
D RF_1294 dksA; DnaK suppressor protein homolog K06204 dksA; RNA polymerase-binding transcription factor
D RF_0872 nusA; N utilization substance protein A, transcription termination factor NusA K02600 nusA; transcription termination/antitermination protein NusA
D RF_1119 nusB; N utilization substance protein B K03625 nusB; transcription antitermination protein NusB
D RF_1151 nusG; Transcription antitermination protein NusG K02601 nusG; transcription termination/antitermination protein NusG
D RF_0256 ksgA; Dimethyladenosine transferase K02528 ksgA; 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase [EC:2.1.1.182]
D RF_0865 N6-adenine-specific methylase K08316 rsmD; 16S rRNA (guanine966-N2)-methyltransferase [EC:2.1.1.171]
D RF_1111 Conserved hypothetical protein K09761 rsmE; 16S rRNA (uracil1498-N3)-methyltransferase [EC:2.1.1.193]
D RF_0118 gidB; Predicted S-adenosylmethionine-dependent methyltransferase GidB K03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170]
D RF_0904 mraW; S-adenosyl-methyltransferase MraW K03438 mraW; 16S rRNA (cytosine1402-N4)-methyltransferase [EC:2.1.1.199]
D RF_1194 Conserved hypothetical protein K07056 rsmI; 16S rRNA (cytidine1402-2'-O)-methyltransferase [EC:2.1.1.198]
D RF_0876 tlyA; Hemolysin A K06442 tlyA; 23S rRNA (cytidine1920-2'-O)/16S rRNA (cytidine1409-2'-O)-methyltransferase [EC:2.1.1.226 2.1.1.227]
D RF_0275 tRNA/rRNA methyltransferase K03218 rlmB; 23S rRNA (guanosine2251-2'-O)-methyltransferase [EC:2.1.1.185]
D RF_1118 rrmJ; Ribosomal RNA large subunit methyltransferase J K02427 rlmE; 23S rRNA (uridine2552-2'-O)-methyltransferase [EC:2.1.1.166]
D RF_0194 unknown K07115 rlmJ; 23S rRNA (adenine2030-N6)-methyltransferase [EC:2.1.1.266]
D RF_0863 rluA2; Ribosomal large subunit pseudouridine synthase K06178 rluB; 23S rRNA pseudouridine2605 synthase [EC:5.4.99.22]
D RF_1023 rluA1; Ribosomal large subunit pseudouridine synthase K06179 rluC; 23S rRNA pseudouridine955/2504/2580 synthase [EC:5.4.99.24]
D RF_1341 Ribosomal large subunit pseudouridine synthases, RluD subfamily K06180 rluD; 23S rRNA pseudouridine1911/1915/1917 synthase [EC:5.4.99.23]
D RF_0555 rimM; 16S rRNA processing protein RimM K02860 rimM; 16S rRNA processing protein RimM
D RF_1025 rne; Ribonuclease E K08300 rne; ribonuclease E [EC:3.1.26.12]
D RF_0535 Conserved hypothetical protein K07447 ruvX; putative pre-16S rRNA nuclease [EC:3.1.-.-]
D RF_0264 ATP-dependent RNA helicase RhlE K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7]
D RF_0248 Conserved GTP-binding protein K03977 engA; GTPase
D RF_1345 Putative translation factor protein K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D RF_0669 rbfA; Ribosome-binding factor A K02834 rbfA; ribosome-binding factor A
D RF_0873 Uncharacterized protein K09748 rimP; ribosome maturation factor RimP
D RF_1284 Iojap-related protein K09710 ybeB; ribosome-associated protein
D RF_1186 Conserved hypothetical protein K07042 ybeY; probable rRNA maturation factor
D RF_0355 ychF; GTP-binding protein YchF K06942 ychF; ribosome-binding ATPase
C 03016 Transfer RNA biogenesis [BR:rfe03016]
D RF_0413 gltX2; Glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D RF_0529 gltX1; Glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D RF_0600 proS; Prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D RF_0423 ileS; Isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D RF_0651 leuS; Leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D RF_0235 metG; Methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D RF_0109 argS; Arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D RF_1138 aspS; Aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D RF_1353 alaS; Alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D RF_0979 thrS; Threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D RF_1249 serS; Seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D RF_0068 cysS; Cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D RF_0229 valS; Valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D RF_0498 hisS; Histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D RF_0647 pheS; Phenylalanyl-tRNA synthetase alpha chain K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D RF_0648 pheT; Phenylalanyl-tRNA synthetase beta chain K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D RF_0877 tyrS; Tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D RF_0824 trpS; Tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D RF_0513 pkcI; Protein kinase C inhibitor 1 K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
D RF_1356 truA; tRNA pseudouridine synthase A K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D RF_0723 truB; tRNA pseudouridine synthase B K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
D RF_0845 iscS; Cysteine desulfurase IscS K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D RF_0846 spl1; Nifs protein homolog K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D RF_1345 Putative translation factor protein K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D RF_0714 miaA; tRNA delta(2)-isopentenylpyrophosphate transferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
D RF_1214 trmE; tRNA modification GTPase TrmE K03650 mnmE; tRNA modification GTPase [EC:3.6.-.-]
D RF_0119 gidA; Glucose-inhibited division protein A K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
D RF_0482 cysQ; 3'(2'),5'-bisphosphate nucleotidase K01082 cysQ; 3'(2'), 5'-bisphosphate nucleotidase [EC:3.1.3.7]
D RF_0347 rnpA; Ribonuclease P K03536 rnpA; ribonuclease P protein component [EC:3.1.26.5]
D RF_RNA19 RNA subunit (M1 RNA) of ribonuclease P K01978 rnpB; M1 RNA
D RF_0403 rph; Ribonuclease PH K00989 rph; ribonuclease PH [EC:2.7.7.56]
D RF_0653 rnd2; Ribonuclease D K03684 rnd; ribonuclease D [EC:3.1.13.5]
D RF_0809 rnd; Ribonuclease D K03684 rnd; ribonuclease D [EC:3.1.13.5]
D RF_0115 abcT1; ABC transporter ATP-binding protein K06020 ettA; energy-dependent translational throttle protein EttA
D RF_0582 lysS; Lysyl-tRNA synthetase K04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6]
D RF_1347 glyQ; Glycyl-tRNA synthetase alpha chain K01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14]
D RF_1346 glyS; Glycyl-tRNA synthetase beta chain K01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14]
D RF_1319 Cytosine deaminase K11991 tadA; tRNA(adenine34) deaminase [EC:3.5.4.33]
D RF_0012 nifR3; Putative TIM-barrel protein, nifR3 family K05540 dusB; tRNA-dihydrouridine synthase B [EC:1.-.-.-]
D RF_1278 miaB; tRNA-i(6)A37 thiotransferase enzyme MiaB K06168 miaB; tRNA-2-methylthio-N6-dimethylallyladenosine synthase [EC:2.8.4.3]
D RF_0646 MiaB-like tRNA modifying enzyme K18707 mtaB; threonylcarbamoyladenosine tRNA methylthiotransferase MtaB [EC:2.8.4.5]
D RF_1172 tRNA/rRNA methyltransferase K02533 lasT; tRNA/rRNA methyltransferase [EC:2.1.1.-]
D RF_0099 trmD; tRNA (guanine-n1)-methyltransferase K00554 trmD; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]
D RF_0496 trmU; tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]
D RF_0843 iscA2; Iron-sulfur cluster assembly accessory protein K13628 iscA; iron-sulfur cluster assembly protein
D RF_0811 gcvT; Glycine cleavage T-protein K06980 ygfZ; tRNA-modifying protein YgfZ
D RF_0330 queA; S-adenosylmethionine:tRNA ribosyltransferase-isomerase K07568 queA; S-adenosylmethionine:tRNA ribosyltransferase-isomerase [EC:2.4.99.17]
D RF_0217 exsB; Trans-regulatory protein ExsB K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20]
D RF_1094 6-pyruvoyl tetrahydropterin synthase K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]
D RF_0351 nrdG; Organic radical activating enzymes K10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3]
D RF_0057 unknown K06879 queF; 7-cyano-7-deazaguanine reductase [EC:1.7.1.13]
D RF_1348 Uncharacterized protein K09765 queH; epoxyqueuosine reductase [EC:1.17.99.6]
D RF_0191 tgt; Queuine tRNA-ribosyltransferase K00773 tgt; queuine tRNA-ribosyltransferase [EC:2.4.2.29]
D RF_0140 tilS; tRNA(Ile)-lysidine synthetase TilS K04075 tilS; tRNA(Ile)-lysidine synthase [EC:6.3.4.19]
D RF_0869 Putative glycoprotein endopeptidase K14742 tsaB; tRNA threonylcarbamoyladenosine biosynthesis protein TsaB
D RF_0146 gcp; Sialoglycoprotease K25706 tsaD; tRNA N6-adenosine threonylcarbamoyltransferase [EC:2.3.1.234]
D RF_0017 Conserved hypothetical protein K06925 tsaE; tRNA threonylcarbamoyladenosine biosynthesis protein TsaE
D RF_0721 pnp; Polyribonucleotide nucleotidyltransferase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
D RF_0095 vapC2; Toxin of toxin-antitoxin system K18828 mvpA; tRNA(fMet)-specific endonuclease VapC [EC:3.1.-.-]
C 03012 Translation factors [BR:rfe03012]
D RF_0871 infB; Translation initiation factor IF-2 K02519 infB; translation initiation factor IF-2
D RF_0760 infC; Translation initiation factor IF-3 K02520 infC; translation initiation factor IF-3
D RF_0070 tsf; Elongation factor EF-Ts K02357 tsf; elongation factor Ts
D RF_0276 tuf; Elongation factor EF-Tu K02358 tuf; elongation factor Tu
D RF_1153 fusA; Elongation factor EF-G K02355 fusA; elongation factor G
D RF_0762 prfA; Peptide chain release factor RF-1 K02835 prfA; peptide chain release factor 1
D RF_1127 rrf; Ribosome recycling factor K02838 frr; ribosome recycling factor
D RF_1344 hemK; Methylase of polypeptide chain release factors, tRNA (guanine-N(7)-)-methyltransferase K02493 hemK; release factor glutamine methyltransferase [EC:2.1.1.297]
D RF_0353 pth; Peptidyl-tRNA hydrolase K01056 PTH1; peptidyl-tRNA hydrolase, PTH1 family [EC:3.1.1.29]
D RF_1292 infA; Translation initiation factor IF-1 K02518 infA; translation initiation factor IF-1
D RF_1049 efp; Translation elongation factor EF-P K02356 efp; elongation factor P
D RF_1001 prfB; Peptide chain release factor RF-2 K02836 prfB; peptide chain release factor 2
C 03110 Chaperones and folding catalysts [BR:rfe03110]
D RF_0150 ClpB protein K03695 clpB; ATP-dependent Clp protease ATP-binding subunit ClpB
D RF_0219 clpX; ATP-dependent Clp protease ATP-binding subunit ClpX K03544 clpX; ATP-dependent Clp protease ATP-binding subunit ClpX
D RF_0516 hslU; Heat shock protein HslVU, ATPase subunit HslU K03667 hslU; ATP-dependent HslUV protease ATP-binding subunit HslU
D RF_1333 htpG; Heat shock protein HtpG K04079 HSP90A; molecular chaperone HtpG
D RF_1084 dnaK; DnaK protein K04043 dnaK; molecular chaperone DnaK
D RF_1063 hscA; Heat shock protein HscA K04044 hscA; molecular chaperone HscA
D RF_0409 groEL; 60 kDa chaperonin K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D RF_1085 dnaJ; DnaJ protein K03686 dnaJ; molecular chaperone DnaJ
D RF_1062 hscB; Co-chaperone Hsc20 K04082 hscB; molecular chaperone HscB
D RF_0402 grpE; GrpE protein K03687 GRPE; molecular chaperone GrpE
D RF_1004 hspC2; Small heat shock protein K13993 HSP20; HSP20 family protein
D RF_p51 hspP2; Small heat shock protein K13993 HSP20; HSP20 family protein
D RF_pd51 hspP2; Small heat shock protein K13993 HSP20; HSP20 family protein
D RF_p52 hspP1; Small heat shock protein K13993 HSP20; HSP20 family protein
D RF_pd52 hspP1; Small heat shock protein K13993 HSP20; HSP20 family protein
D RF_0408 groES; 10 kDa chaperonin K04078 groES; chaperonin GroES
D RF_1166 htrA; Periplasmic serine protease K04771 degP; serine protease Do [EC:3.4.21.107]
D RF_0139 ftsH; ATP-dependent metalloprotease FtsH K03798 ftsH; cell division protease FtsH [EC:3.4.24.-]
D RF_0030 atpB; ATP synthase A chain K02108 ATPF0A; F-type H+-transporting ATPase subunit a
D RF_0704 unknown K07346 fimC; fimbrial chaperone protein
D RF_0055 secB; Protein-export protein SecB K03071 secB; preprotein translocase subunit SecB
D RF_0913 unknown K09796 pccA; periplasmic copper chaperone A
D RF_0002 trxA; Thioredoxin K03671 TXN; thioredoxin
D RF_1059 grxC1; Glutaredoxin, GrxC family K03676 grxC; glutaredoxin 3
D RF_1190 grxC2; Glutaredoxin-like protein grla K07390 grxD; monothiol glutaredoxin
C 04131 Membrane trafficking [BR:rfe04131]
D RF_0120 ndk; Nucleoside diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
D RF_1333 htpG; Heat shock protein HtpG K04079 HSP90A; molecular chaperone HtpG
C 04121 Ubiquitin system [BR:rfe04121]
C 03051 Proteasome [BR:rfe03051]
D RF_1333 htpG; Heat shock protein HtpG K04079 HSP90A; molecular chaperone HtpG
C 03032 DNA replication proteins [BR:rfe03032]
D RF_0180 rnhA; Ribonuclease H K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D RF_0138 Site-specific DNA methylase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D RF_0137 Site-specific DNA methylase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D RF_1108 hupA; DNA-binding protein HU K03530 hupB; DNA-binding protein HU-beta
D RF_0201 himA; Integration host factor alpha-subunit K04764 ihfA; integration host factor subunit alpha
D RF_0767 himD; Integration host factor beta-subunit K05788 ihfB; integration host factor subunit beta
D RF_0364 dnaA; Chromosomal replication initiator protein DnaA K02313 dnaA; chromosomal replication initiator protein
D RF_0860 dnaB; Replicative DNA helicase K02314 dnaB; replicative DNA helicase [EC:5.6.2.3]
D RF_1358 dnaG; DNA primase K02316 dnaG; DNA primase [EC:2.7.7.101]
D RF_1325 ssb; Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D RF_1244 dnaE; DNA polymerase III alpha chain K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
D RF_0649 dnaN; DNA polymerase III beta chain K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
D RF_1375 unknown K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
D RF_1078 holA; DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
D RF_1107 holB; DNA polymerase III delta subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
D RF_0176 dnaQ; DNA polymerase III epsilon chain K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
D RF_p34 DNA polymerase III, epsilon subunit-like protein K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
D RF_p53 DNA polymerase III, epsilon subunit-like protein K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
D RF_pd53 DNA polymerase III, epsilon subunit-like protein K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
D RF_1364 dnaX; DNA polymerase III gamma and tau chains K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D RF_1061 rnhB; Ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4]
D RF_0192 ligA; DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D RF_0123 dam; Site-specific DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
D RF_1055 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
D RF_0947 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
D RF_0107 parC; Topoisomerase IV subunit A K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2]
D RF_0988 parE; DNA topoisomerase IV, B subunit K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2]
D RF_0530 topA; DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
C 03036 Chromosome and associated proteins [BR:rfe03036]
D RF_0138 Site-specific DNA methylase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D RF_0137 Site-specific DNA methylase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D RF_1176 rnc; Ribonuclease III K03685 rnc; ribonuclease III [EC:3.1.26.3]
D RF_1108 hupA; DNA-binding protein HU K03530 hupB; DNA-binding protein HU-beta
D RF_0201 himA; Integration host factor alpha-subunit K04764 ihfA; integration host factor subunit alpha
D RF_0767 himD; Integration host factor beta-subunit K05788 ihfB; integration host factor subunit beta
D RF_0364 dnaA; Chromosomal replication initiator protein DnaA K02313 dnaA; chromosomal replication initiator protein
D RF_1271 Strees induced DNA-binding protein K04047 dps; starvation-inducible DNA-binding protein
D RF_1033 ftsA; Cell division protein FtsA K03590 ftsA; cell division protein FtsA
D RF_0902 pbpA2; Penicillin-binding protein K03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4]
D RF_1307 ftsK; Cell division protein FtsK-like protein K03466 ftsK; DNA segregation ATPase FtsK/SpoIIIE, S-DNA-T family
D RF_0903 ftsL; Cell division protein FtsL K03586 ftsL; cell division protein FtsL
D RF_1034 ftsQ; Cell division protein FtsQ K03589 ftsQ; cell division protein FtsQ
D RF_0635 ftsW; Cell division protein FtsW K03588 ftsW; cell division protein FtsW
D RF_0270 ftsZ; Cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ
D RF_0328 n2B; Putative ATPase n2B K06916 zapE; cell division protein ZapE
D RF_1232 mreB; Rod shape-determining protein MreB K03569 mreB; rod shape-determining protein MreB and related proteins
D RF_1231 mreC; Rod shape-determining protein MreC K03570 mreC; rod shape-determining protein MreC
D RF_0453 rodA; Rod shape-determining protein RodA K05837 rodA; rod shape determining protein RodA
D RF_0117 soj; ATPases involved in chromosome partitioning K03496 parA; chromosome partitioning protein
D RF_p23 parA2; Plasmid stability protein ParA K03496 parA; chromosome partitioning protein
D RF_p03 parA1; Chromosome partitioning ParA family protein K03496 parA; chromosome partitioning protein
D RF_pd03 parA1; Chromosome partitioning ParA family protein K03496 parA; chromosome partitioning protein
D RF_1142 Chromosome partitioning protein K03496 parA; chromosome partitioning protein
D RF_0116 ParB-like partition proteins K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein
D RF_p35 parB; ParB-like nuclease domain K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein
D RF_0107 parC; Topoisomerase IV subunit A K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2]
D RF_0988 parE; DNA topoisomerase IV, B subunit K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2]
D RF_0119 gidA; Glucose-inhibited division protein A K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
D RF_0118 gidB; Predicted S-adenosylmethionine-dependent methyltransferase GidB K03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170]
D RF_1295 xerC; Tyrosine recombinase XerC K03733 xerC; integrase/recombinase XerC
D RF_0571 xerD; Tyrosine recombinase XerD K04763 xerD; integrase/recombinase XerD
D RF_1169 mrp; Mrp protein K03593 mrp; ATP-binding protein involved in chromosome partitioning
D RF_1308 fic; Fic K04095 fic; cell filamentation protein, protein adenylyltransferase [EC:2.7.7.108]
D RF_0085 Hypothetical GTP-binding protein K03978 engB; GTP-binding protein
C 03400 DNA repair and recombination proteins [BR:rfe03400]
D RF_0916 dat; Methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D RF_0560 mpg; DNA-3-methyladenine glycosidase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
D RF_1191 nth; Endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D RF_0595 mutT; ADP-ribose pyrophosphatase MutT K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D RF_0620 dut; Deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D RF_0915 Methylated-DNA--protein-cysteine methyltransferase K10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response / methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]
D RF_1340 Uracil-DNA glycosylase, family 4 K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
D RF_0242 mutM; Formamidopyrimidine-DNA glycosidase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
D RF_0250 xth2; Exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D RF_1021 xth1; Exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D RF_0763 recJ; Single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D RF_0192 ligA; DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D RF_1324 uvrA; Excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
D RF_1060 uvrB; Excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
D RF_0912 uvrC; Excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C
D RF_0687 uvrD; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D RF_1146 rpoB; DNA-directed RNA polymerase beta chain K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
D RF_1145 rpoC; DNA-directed RNA polymerase beta prime chain K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
D RF_0302 rpoA; DNA-directed RNA polymerase alpha chain K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
D RF_0944 rpoZ; DNA-directed RNA polymerase omega chain K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
D RF_0367 mfd; Transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
D RF_0483 mutS; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
D RF_1387 mutL; DNA mismatch repair protein MutL K03572 mutL; DNA mismatch repair protein MutL
D RF_0253 xseA; Exodeoxyribonuclease VII, large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
D RF_0557 xseB; Exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D RF_1244 dnaE; DNA polymerase III alpha chain K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
D RF_0649 dnaN; DNA polymerase III beta chain K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
D RF_1375 unknown K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
D RF_1078 holA; DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
D RF_1107 holB; DNA polymerase III delta subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
D RF_0176 dnaQ; DNA polymerase III epsilon chain K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
D RF_p34 DNA polymerase III, epsilon subunit-like protein K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
D RF_p53 DNA polymerase III, epsilon subunit-like protein K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
D RF_pd53 DNA polymerase III, epsilon subunit-like protein K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
D RF_1364 dnaX; DNA polymerase III gamma and tau chains K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D RF_1325 ssb; Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D RF_0123 dam; Site-specific DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
D RF_1221 recA; RecA protein K03553 recA; recombination protein RecA
D RF_0604 ruvA; Holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
D RF_0606 ruvB; Holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
D RF_1173 ruvC; Crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D RF_0858 priA; Primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
D RF_0866 radA; DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
D RF_0035 recF; DNA replication and repair protein RecF K03629 recF; DNA replication and repair protein RecF
D RF_0378 recG; ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
D RF_0868 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
D RF_0672 recR; Recombination protein RecR K06187 recR; recombination protein RecR
D RF_1089 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D RF_0174 ATP-dependent helicase K16898 addA; ATP-dependent helicase/nuclease subunit A [EC:5.6.2.4 3.1.-.-]
D RF_0624 unknown K16899 addB; ATP-dependent helicase/nuclease subunit B [EC:5.6.2.4 3.1.-.-]
D RF_1055 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
D RF_0947 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
D RF_0530 topA; DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
D RF_1108 hupA; DNA-binding protein HU K03530 hupB; DNA-binding protein HU-beta
D RF_0201 himA; Integration host factor alpha-subunit K04764 ihfA; integration host factor subunit alpha
D RF_0767 himD; Integration host factor beta-subunit K05788 ihfB; integration host factor subunit beta
D RF_1397 Prophage antirepressor K14623 dinD; DNA-damage-inducible protein D
D RF_0709 nrdA; Ribonucleoside-diphosphate reductase alpha chain K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D RF_0710 nrdB; Ribonucleoside-diphosphate reductase beta chain K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C 03029 Mitochondrial biogenesis [BR:rfe03029]
D RF_1009 petB; Cytochrome b K00412 CYTB; ubiquinol-cytochrome c reductase cytochrome b subunit
D RF_0871 infB; Translation initiation factor IF-2 K02519 infB; translation initiation factor IF-2
D RF_0760 infC; Translation initiation factor IF-3 K02520 infC; translation initiation factor IF-3
D RF_0070 tsf; Elongation factor EF-Ts K02357 tsf; elongation factor Ts
D RF_0276 tuf; Elongation factor EF-Tu K02358 tuf; elongation factor Tu
D RF_1153 fusA; Elongation factor EF-G K02355 fusA; elongation factor G
D RF_1174 era; GTP-binding protein Era K03595 era; GTPase
D RF_0877 tyrS; Tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D RF_0651 leuS; Leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D RF_1138 aspS; Aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D RF_0109 argS; Arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D RF_1129 gatA; Glutamyl-tRNA(Gln) amidotransferase subunit A K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7]
D RF_1130 gatB; Glutamyl-tRNA(Gln) amidotransferase subunit B K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7]
D RF_1128 gatC; Glutamyl-tRNA(Gln) amidotransferase subunit C K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7]
D RF_1325 ssb; Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D RF_1121 omp1; Outer membrane protein omp1 K07277 SAM50; outer membrane protein insertion porin family
D RF_1084 dnaK; DnaK protein K04043 dnaK; molecular chaperone DnaK
D RF_0402 grpE; GrpE protein K03687 GRPE; molecular chaperone GrpE
D RF_0409 groEL; 60 kDa chaperonin K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D RF_0408 groES; 10 kDa chaperonin K04078 groES; chaperonin GroES
D RF_1085 dnaJ; DnaJ protein K03686 dnaJ; molecular chaperone DnaJ
D RF_0845 iscS; Cysteine desulfurase IscS K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D RF_0846 spl1; Nifs protein homolog K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D RF_1062 hscB; Co-chaperone Hsc20 K04082 hscB; molecular chaperone HscB
D RF_1190 grxC2; Glutaredoxin-like protein grla K07390 grxD; monothiol glutaredoxin
D RF_0134 Uncharacterized conserved protein K18164 NDUFAF7; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 7
D RF_1169 mrp; Mrp protein K03593 mrp; ATP-binding protein involved in chromosome partitioning
D RF_0550 cyoB; Protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141]
D RF_0494 cox11; Cytochrome c oxidase assembly protein cox11 K02258 COX11; cytochrome c oxidase assembly protein subunit 11
D RF_1024 coxW; Cytochrome c oxidase assembly protein K02259 COX15; heme a synthase [EC:1.17.99.9]
D RF_0131 yidC; Preprotein translocase subunit YidC K03217 yidC; YidC/Oxa1 family membrane protein insertase
D RF_0175 surf1; Surfeit locus protein 1 K14998 SURF1; surfeit locus 1 family protein
D RF_0043 Sco2 protein precursor K07152 SCO1; protein SCO1
D RF_0960 Sco2 protein precursor K07152 SCO1; protein SCO1
D RF_1333 htpG; Heat shock protein HtpG K04079 HSP90A; molecular chaperone HtpG
B
B 09183 Protein families: signaling and cellular processes
C 02000 Transporters [BR:rfe02000]
D RF_0607 msbA1; Multidrug resistance protein K11085 msbA; ATP-binding cassette, subfamily B, bacterial MsbA [EC:7.5.2.6]
D RF_1057 atm1; Multidrug resistance protein Atm1 K24821 atm1; ATP-binding cassette, subfamily B, heavy metal transporter
D RF_0214 msbA2; Multidrug resistance protein K06147 ABCB-BAC; ATP-binding cassette, subfamily B, bacterial
D RF_0331 abcT3; Multidrug resistance ABC transporter ATP-binding protein K06147 ABCB-BAC; ATP-binding cassette, subfamily B, bacterial
D RF_0981 mdlB; ABC-type multidrug transport system, ATPase and permease components K06147 ABCB-BAC; ATP-binding cassette, subfamily B, bacterial
D RF_0511 aprD; Alkaline protease secretion ATP-binding protein AprD K12536 hasD; ATP-binding cassette, subfamily C, type I secretion system permease/ATPase
D RF_1225 uup; ABC transporter ATP-binding protein Uup K15738 uup; ABC transport system ATP-binding/permease protein
D RF_0182 ABC transporter substrate binding protein K02067 mlaD; phospholipid/cholesterol/gamma-HCH transport system substrate-binding protein
D RF_0080 ABC transporter permease protein K02066 mlaE; phospholipid/cholesterol/gamma-HCH transport system permease protein
D RF_0081 mkl; Ribonucleotide ABC transporter ATP-binding protein K02065 mlaF; phospholipid/cholesterol/gamma-HCH transport system ATP-binding protein
D RF_0077 unknown K07323 mlaC; phospholipid transport system substrate-binding protein
D RF_0578 unknown K01989 K01989; putative tryptophan/tyrosine transport system substrate-binding protein
D RF_0579 ABC transporter permease protein K05832 K05832; putative tryptophan/tyrosine transport system permease protein
D RF_1131 yqiX; Amino acid ABC transporter substrate binding protein K02030 ABC.PA.S; polar amino acid transport system substrate-binding protein
D RF_0251 Predicted membrane protein K02030 ABC.PA.S; polar amino acid transport system substrate-binding protein
D RF_0252 unknown K02030 ABC.PA.S; polar amino acid transport system substrate-binding protein
D RF_1156 yqiY; Amino acid ABC transporter permease protein K02029 ABC.PA.P; polar amino acid transport system permease protein
D RF_1370 glnQ; Glutamine ABC transporter ATP-binding protein K02028 ABC.PA.A; polar amino acid transport system ATP-binding protein [EC:7.4.2.1]
D RF_0018 znuA; Zinc/manganese ABC transporter substrate binding protein K09815 znuA; zinc transport system substrate-binding protein
D RF_0415 znuB; Zinc/manganese ABC transporter permease protein K09816 znuB; zinc transport system permease protein
D RF_1323 znuC; Zinc ABC transporter ATP-binding protein K09817 znuC; zinc transport system ATP-binding protein [EC:7.2.2.20]
D RF_0526 bioY1; BioY family protein K03523 bioY; biotin transport system substrate-specific component
D RF_0739 bioY2; BioY family protein K03523 bioY; biotin transport system substrate-specific component
D RF_0004 rfbA; O-antigen export system permease protein RfbA K09690 wzm; homopolymeric O-antigen transport system permease protein
D RF_0003 rfbE; O-antigen export system ATP-binding protein RfbE K09691 wzt; homopolymeric O-antigen transport system ATP-binding protein [EC:7.5.2.14]
D RF_1374 Predicted permeases K07091 lptF; lipopolysaccharide export system permease protein
D RF_1233 Predicted permeases K11720 lptG; lipopolysaccharide export system permease protein
D RF_0717 abcT2; ABC transporter ATP-binding protein K06861 lptB; lipopolysaccharide export system ATP-binding protein [EC:7.5.2.5]
D RF_0211 Lipoprotein releasing system, transmembrane protein K09808 lolC_E; lipoprotein-releasing system permease protein
D RF_0210 lolD; Lipoprotein releasing system ATP-binding protein LolD K09810 lolD; lipoprotein-releasing system ATP-binding protein [EC:7.6.2.-]
D RF_1318 ccmC; Heme exporter protein C K02195 ccmC; heme exporter protein C
D RF_1012 ccmB; Heme exporter protein B K02194 ccmB; heme exporter protein B
D RF_1259 ccmA; Heme exporter protein A K02193 ccmA; heme exporter protein A [EC:7.6.2.5]
D RF_1349 proP6; Proline/betaine transporter K03762 proP; MFS transporter, MHS family, proline/betaine transporter
D RF_1395 proP7; Proline/betaine transporter K03762 proP; MFS transporter, MHS family, proline/betaine transporter
D RF_0391 proP; Permeases of the major facilitator superfamily K03762 proP; MFS transporter, MHS family, proline/betaine transporter
D RF_0439 MFS type sugar transporter K03762 proP; MFS transporter, MHS family, proline/betaine transporter
D RF_0586 proP3; Proline/betaine transporter K03762 proP; MFS transporter, MHS family, proline/betaine transporter
D RF_0121 uhpC; Sugar phosphate permease K02445 glpT; MFS transporter, OPA family, glycerol-3-phosphate transporter
D RF_0608 ampG4; AmpG protein K08218 ampG; MFS transporter, PAT family, beta-lactamase induction signal transducer AmpG
D RF_0834 ampG1; AmpG-related permease K08218 ampG; MFS transporter, PAT family, beta-lactamase induction signal transducer AmpG
D RF_0212 bcr2; Bicyclomycin resistance protein K07552 bcr; MFS transporter, DHA1 family, multidrug resistance protein
D RF_0358 bcr1; Bicyclomycin resistance protein K07552 bcr; MFS transporter, DHA1 family, multidrug resistance protein
D RF_1124 emrB; Multidrug resistance protein B K03446 emrB; MFS transporter, DHA2 family, multidrug resistance protein
D RF_0736 Glutathione S-transferase K00799 GST; glutathione S-transferase [EC:2.5.1.18]
D RF_0132 Conserved hypothetical membrane protein K16053 ybdG; miniconductance mechanosensitive channel
D RF_0951 mgtE; Magnesium transporter K06213 mgtE; magnesium transporter
D RF_0504 tolQ; TolQ protein K03562 tolQ; biopolymer transport protein TolQ
D RF_0505 tolR; TolR protein K03560 tolR; biopolymer transport protein TolR
D RF_0433 corA; Magnesium and cobalt transport protein CorA K03284 corA; magnesium transporter
D RF_0208 Hemolysin homolog K03699 tlyC; magnesium and cobalt exporter, CNNM family
D RF_0705 P pilus assembly protein FimD K07347 fimD; outer membrane usher protein
D RF_0706 P pilus assembly protein FimD K07347 fimD; outer membrane usher protein
D RF_0985 tolC; Type I secretion outer membrane protein, TolC family K12340 tolC; outer membrane protein
D RF_0643 RND efflux system, outer membrane protein K18139 oprM; outer membrane protein, multidrug efflux system
D RF_1121 omp1; Outer membrane protein omp1 K07277 SAM50; outer membrane protein insertion porin family
D RF_1088 unknown K05807 bamD; outer membrane protein assembly factor BamD
D RF_0718 Uncharacterized protein K09774 lptA; lipopolysaccharide export system protein LptA
D RF_0719 unknown K11719 lptC; lipopolysaccharide export system protein LptC
D RF_0254 ostA; Organic solvent tolerance protein homolog K04744 lptD; LPS-assembly protein
D RF_1185 tlyC; Hemolysin C K06189 corC; hemolysin (HlyC) family protein
D RF_1320 Cation diffusion facilitator family transporter K13283 fieF; ferrous-iron efflux pump FieF
D RF_0061 sam; S-adenosylmethionine transporter K15270 sam; S-adenosylmethionine uptake transporter
D RF_1381 nhaA; Na+/H+ antiporter NhaA K03313 nhaA; Na+:H+ antiporter, NhaA family
D RF_1283 kefB; Glutathione-regulated potassium-efflux system protein KefB K03455 KEA1_2_3; K+:H+ antiporter
D RF_0862 Putative to amino acid permeases K03834 tyrP; tyrosine-specific transport protein
D RF_1013 mnhB; Multisubunit Na+/H+ antiporter, MnhB subunit K05566 mnhB; multicomponent Na+:H+ antiporter subunit B
D RF_0461 mnhC; Multisubunit Na+/H+ antiporter, MnhC subunit K05567 mnhC; multicomponent Na+:H+ antiporter subunit C
D RF_0455 nuoL3; NADH dehydrogenase I chain N K05568 mnhD; multicomponent Na+:H+ antiporter subunit D
D RF_0458 nuoL2; NADH dehydrogenase I chain L K05568 mnhD; multicomponent Na+:H+ antiporter subunit D
D RF_0460 nuoN2; NADH:ubiquinone oxidoreductase subunit 2 (chain N) K05568 mnhD; multicomponent Na+:H+ antiporter subunit D
D RF_1125 mnhE; Multisubunit Na+/H+ antiporter, MnhE subunit K05569 mnhE; multicomponent Na+:H+ antiporter subunit E
D RF_0894 Multisubunit Na+/H+ antiporter, MnhF subunit K05570 mnhF; multicomponent Na+:H+ antiporter subunit F
D RF_1014 Monovalent cation/proton antiporter, MnhG/PhaG subunit K05571 mnhG; multicomponent Na+:H+ antiporter subunit G
D RF_0963 mviN; Integral membrane protein MviN K03980 murJ; putative peptidoglycan lipid II flippase
D RF_0583 Predicted permease K13936 mdcF; malonate transporter and related proteins
D RF_0679 Predicted permease K24180 mleP; malate permease and related proteins
D RF_0832 lysE; Lysine efflux permease K06895 lysE; L-lysine exporter family protein LysE/ArgO
D RF_0833 unknown K06895 lysE; L-lysine exporter family protein LysE/ArgO
D RF_0401 perM; Permease PerM homolog K03548 perM; putative permease
D RF_0066 Conserved hypothetical integral membrane protein K09125 yhhQ; queuosine precursor transporter
D RF_0635 ftsW; Cell division protein FtsW K03588 ftsW; cell division protein FtsW
D RF_0614 FTR1 family protein K07243 FTR; high-affinity iron transporter
D RF_0249 unknown K15383 K15383; MtN3 and saliva related transmembrane protein
D RF_1234 pal; Peptidoglycan-associated lipoprotein precursor K03640 pal; peptidoglycan-associated lipoprotein
D RF_0492 tolB; TolB protein precursor K03641 tolB; TolB protein
D RF_1044 emrA; Multidrug resistance protein A K03543 emrA; membrane fusion protein, multidrug efflux system
D RF_0510 aprE; Alkaline protease secretion protein AprE K12537 hasE; membrane fusion protein, type I secretion system
D RF_0642 mfp; Membrane-fusion protein component of the RND family transporter K07799 mdtA; membrane fusion protein, multidrug efflux system
D RF_0207 ccmF; Cytochrome c-type biogenesis protein CcmF K02198 ccmF; cytochrome c-type biogenesis protein CcmF
C 02044 Secretion system [BR:rfe02044]
D RF_0985 tolC; Type I secretion outer membrane protein, TolC family K12340 tolC; outer membrane protein
D RF_0511 aprD; Alkaline protease secretion ATP-binding protein AprD K12536 hasD; ATP-binding cassette, subfamily C, type I secretion system permease/ATPase
D RF_0510 aprE; Alkaline protease secretion protein AprE K12537 hasE; membrane fusion protein, type I secretion system
D RF_0087 virB3; Type IV secretory pathway, VirB3-like protein K03198 virB3; type IV secretion system protein VirB3
D RF_0088 virB4_1; Type IV secretion/conjugal transfer ATPase, VirB4 family K03199 virB4; type IV secretion system protein VirB4 [EC:7.4.2.8]
D RF_1250 virB4_2; Type IV secretion/conjugal transfer ATPase, VirB4 family K03199 virB4; type IV secretion system protein VirB4 [EC:7.4.2.8]
D RF_0089 virB6_1; TrbL/VirB6 plasmid Conjugative transfer protein K03201 virB6; type IV secretion system protein VirB6
D RF_0090 virB6_2; TrbL/VirB6 plasmid Conjugative transfer protein K03201 virB6; type IV secretion system protein VirB6
D RF_0092 virB6_4; TrbL/VirB6 plasmid Conjugative transfer protein K03201 virB6; type IV secretion system protein VirB6
D RF_0093 virB6_5; TrbL/VirB6 plasmid Conjugative transfer protein K03201 virB6; type IV secretion system protein VirB6
D RF_0091 virB6_3; TrbL/VirB6 plasmid Conjugative transfer protein K03201 virB6; type IV secretion system protein VirB6
D RF_0463 virB8_1; VirB8 protein K03203 virB8; type IV secretion system protein VirB8
D RF_0465 virB8_2; VirB8 protein K03203 virB8; type IV secretion system protein VirB8
D RF_0462 virB9_1; VirB9 protein K03204 virB9; type IV secretion system protein VirB9
D RF_0466 virB9_2; VirB9 protein precursor K03204 virB9; type IV secretion system protein VirB9
D RF_0467 virB10; VirB10 protein K03195 virB10; type IV secretion system protein VirB10
D RF_0468 virB11; VirB11 protein K03196 virB11; type IV secretion system protein VirB11 [EC:7.4.2.8]
D RF_0469 virD4; VirD4 protein K03205 virD4; type IV secretion system protein VirD4 [EC:7.4.2.8]
D RF_0704 unknown K07346 fimC; fimbrial chaperone protein
D RF_0705 P pilus assembly protein FimD K07347 fimD; outer membrane usher protein
D RF_0706 P pilus assembly protein FimD K07347 fimD; outer membrane usher protein
D RF_0707 unknown K27078 cupE; spore coat protein U domain-containing protein, fimbrial subunit CupE1/2/3/6
D RF_0703 unknown K27078 cupE; spore coat protein U domain-containing protein, fimbrial subunit CupE1/2/3/6
D RF_0941 secA; Preprotein translocase SecA subunit K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]
D RF_0055 secB; Protein-export protein SecB K03071 secB; preprotein translocase subunit SecB
D RF_0959 secD; Protein-export membrane protein SecD K03072 secD; preprotein translocase subunit SecD
D RF_1152 secE; Preprotein translocase SecE subunit K03073 secE; preprotein translocase subunit SecE
D RF_1179 secF; Protein-export membrane protein secF K03074 secF; preprotein translocase subunit SecF
D RF_0104 secG; Protein-export membrane protein SecG K03075 secG; preprotein translocase subunit SecG
D RF_0298 secY; Preprotein translocase SecY subunit K03076 secY; preprotein translocase subunit SecY
D RF_1106 ffh; Signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
D RF_1238 ftsY; Signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor
D RF_0958 yajC; Preprotein translocase YajC subunit K03210 yajC; preprotein translocase subunit YajC
D RF_0131 yidC; Preprotein translocase subunit YidC K03217 yidC; YidC/Oxa1 family membrane protein insertase
D RF_1196 tatA; Twin-arginine translocation protein K03116 tatA; sec-independent protein translocase protein TatA
D RF_1248 tatC; Sec-independent protein translocase protein TatC K03118 tatC; sec-independent protein translocase protein TatC
C 02042 Bacterial toxins [BR:rfe02042]
D RF_0208 Hemolysin homolog K03699 tlyC; magnesium and cobalt exporter, CNNM family
D RF_p56 Hyaluronidase K01197 hya; hyaluronoglucosaminidase [EC:3.2.1.35]
D RF_pd56 Hyaluronidase K01197 hya; hyaluronoglucosaminidase [EC:3.2.1.35]
C 02022 Two-component system [BR:rfe02022]
D RF_0657 envZ; Osmolarity sensor protein EnvZ K07638 envZ; two-component system, OmpR family, osmolarity sensor histidine kinase EnvZ [EC:2.7.13.3]
D RF_0658 ompR; PetR protein K07659 ompR; two-component system, OmpR family, phosphate regulon response regulator OmpR
D RF_0427 ntrY; Nitrogen regulation protein NtrY K13598 ntrY; two-component system, NtrC family, nitrogen regulation sensor histidine kinase NtrY [EC:2.7.13.3]
D RF_0895 ntrX; Nitrogen assimilation regulatory protein NtrX K13599 ntrX; two-component system, NtrC family, nitrogen regulation response regulator NtrX
D RF_0990 barA; Histidine kinase sensor protein K07716 pleC; two-component system, cell cycle sensor histidine kinase PleC [EC:2.7.13.3]
D RF_1050 Regulatory components of sensory transduction system K02488 pleD; two-component system, cell cycle response regulator [EC:2.7.7.65]
D RF_0056 czcR; Transcriptional activator protein CzcR K13584 ctrA; two-component system, cell cycle response regulator CtrA
C 02035 Bacterial motility proteins [BR:rfe02035]
D RF_0704 unknown K07346 fimC; fimbrial chaperone protein
D RF_0705 P pilus assembly protein FimD K07347 fimD; outer membrane usher protein
D RF_0706 P pilus assembly protein FimD K07347 fimD; outer membrane usher protein
D RF_0707 unknown K27078 cupE; spore coat protein U domain-containing protein, fimbrial subunit CupE1/2/3/6
D RF_0703 unknown K27078 cupE; spore coat protein U domain-containing protein, fimbrial subunit CupE1/2/3/6
C 03037 Cilium and associated proteins
C 04812 Cytoskeleton proteins [BR:rfe04812]
D RF_1232 mreB; Rod shape-determining protein MreB K03569 mreB; rod shape-determining protein MreB and related proteins
D RF_0270 ftsZ; Cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ
D RF_1033 ftsA; Cell division protein FtsA K03590 ftsA; cell division protein FtsA
D RF_0117 soj; ATPases involved in chromosome partitioning K03496 parA; chromosome partitioning protein
D RF_p23 parA2; Plasmid stability protein ParA K03496 parA; chromosome partitioning protein
D RF_p03 parA1; Chromosome partitioning ParA family protein K03496 parA; chromosome partitioning protein
D RF_pd03 parA1; Chromosome partitioning ParA family protein K03496 parA; chromosome partitioning protein
D RF_1142 Chromosome partitioning protein K03496 parA; chromosome partitioning protein
D RF_0116 ParB-like partition proteins K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein
D RF_p35 parB; ParB-like nuclease domain K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein
C 04147 Exosome [BR:rfe04147]
D RF_1333 htpG; Heat shock protein HtpG K04079 HSP90A; molecular chaperone HtpG
D RF_0532 tdpX1; Thioredoxin peroxidase 1 K03386 PRDX2_4; peroxiredoxin 2/4 [EC:1.11.1.24]
D RF_0409 groEL; 60 kDa chaperonin K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D RF_1084 dnaK; DnaK protein K04043 dnaK; molecular chaperone DnaK
D RF_0276 tuf; Elongation factor EF-Tu K02358 tuf; elongation factor Tu
D RF_0513 pkcI; Protein kinase C inhibitor 1 K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
D RF_0163 paaJ; Acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D RF_0299 adk; Adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3]
D RF_0728 glnA; Glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D RF_0856 hemB; Delta-aminolevulinic acid dehydratase K01698 hemB; porphobilinogen synthase [EC:4.2.1.24]
D RF_0997 Putative pterin-4-alpha-carbinolamine dehydratase (PHS) K01724 PCBD; 4a-hydroxytetrahydrobiopterin dehydratase [EC:4.2.1.96]
D RF_0807 lpdA2; Dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D RF_1270 lpdA1; Dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
C 02048 Prokaryotic defense system [BR:rfe02048]
D RF_0918 Type I site-specific restriction-modification system, R (restriction) subunit K01153 hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3]
D RF_0919 Type I site-specific restriction-modification system, R (restriction) subunit K01153 hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3]
D RF_p07 Type I restriction-modification system methyltransferase subunit K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72]
D RF_pd07 Type I restriction-modification system methyltransferase subunit K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72]
D RF_0123 dam; Site-specific DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
D RF_0138 Site-specific DNA methylase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D RF_0137 Site-specific DNA methylase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D RF_1343 Growth inhibitor K07171 mazF; mRNA interferase MazF [EC:3.1.-.-]
D RF_1368 Cytotoxic translational repressor of toxin-antitoxin system RelE K06218 relE; mRNA interferase RelE/StbE
D RF_0956 Cytotoxic translational repressor of toxin-antitoxin system RelE K06218 relE; mRNA interferase RelE/StbE
D RF_0016 Probable toxin of toxin-antitoxin system K06218 relE; mRNA interferase RelE/StbE
D RF_1286 Cytotoxic translational repressor of toxin-antitoxin system RelE K06218 relE; mRNA interferase RelE/StbE
D RF_1272 Cytotoxic translational repressor of toxin-antitoxin system RelE K06218 relE; mRNA interferase RelE/StbE
D RF_0898 Cytotoxic translational repressor of toxin-antitoxin system RelE K06218 relE; mRNA interferase RelE/StbE
D RF_0899 Probable antitoxin of toxin-antitoxin system K18918 relB; RHH-type transcriptional regulator, rel operon repressor / antitoxin RelB
D RF_0957 Probable antitoxin of toxin-antitoxin system K18918 relB; RHH-type transcriptional regulator, rel operon repressor / antitoxin RelB
D RF_1369 Antitoxin of toxin-antitoxin system StbD K18923 stbD; antitoxin StbD
D RF_0334 Conserved hypothetical protein K19157 yafQ; mRNA interferase YafQ [EC:3.1.-.-]
D RF_0335 relB1; DNA-damage-inducible protein J K07473 dinJ; DNA-damage-inducible protein J
D RF_1373 dinJ; DNA-damage-inducible protein J K07473 dinJ; DNA-damage-inducible protein J
D RF_0827 relB2; DNA-damage-inducible protein J K07473 dinJ; DNA-damage-inducible protein J
D RF_0911 Probable toxin of toxin-antitoxin system K19158 yoeB; toxin YoeB [EC:3.1.-.-]
D RF_0490 Probable toxin of toxin-antitoxin system K19158 yoeB; toxin YoeB [EC:3.1.-.-]
D RF_0792 Probable toxin of toxin-antitoxin system K19158 yoeB; toxin YoeB [EC:3.1.-.-]
D RF_0910 Antitoxin of toxin-antitoxin system StbD K19159 yefM; antitoxin YefM
D RF_0489 Probable antitoxin of toxin-antitoxin stability system K19159 yefM; antitoxin YefM
D RF_0787 Toxin of toxin-antitoxin system ParE K19092 parE1_3_4; toxin ParE1/3/4
D RF_1160 unknown K07746 parD1_3_4; antitoxin ParD1/3/4
D RF_1339 Predicted transcriptional regulator K07746 parD1_3_4; antitoxin ParD1/3/4
D RF_0015 Antitoxin of toxin-antitoxin system StbD K19165 phd; antitoxin Phd
D RF_0536 Plasmid maintenance system antidote protein K21498 higA-1; antitoxin HigA-1
D RF_0095 vapC2; Toxin of toxin-antitoxin system K18828 mvpA; tRNA(fMet)-specific endonuclease VapC [EC:3.1.-.-]
D RF_0094 vapB2; Antitoxin of toxin-antitoxin system VapB K18829 mvpT; antitoxin VapB
D RF_0270 ftsZ; Cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ
D RF_1232 mreB; Rod shape-determining protein MreB K03569 mreB; rod shape-determining protein MreB and related proteins
D RF_0107 parC; Topoisomerase IV subunit A K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2]
D RF_0988 parE; DNA topoisomerase IV, B subunit K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2]
D RF_0413 gltX2; Glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D RF_0529 gltX1; Glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D RF_0366 unknown K09159 cptB; antitoxin CptB
D RF_0845 iscS; Cysteine desulfurase IscS K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D RF_0846 spl1; Nifs protein homolog K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
C 04030 G protein-coupled receptors
C 04050 Cytokine receptors
C 04054 Pattern recognition receptors
C 03310 Nuclear receptors
C 04040 Ion channels
C 04031 GTP-binding proteins
C 04052 Cytokines and neuropeptides
C 04515 Cell adhesion molecules
C 04090 CD molecules
C 01504 Antimicrobial resistance genes [BR:rfe01504]
D RF_0774 Streptomycin 6-kinase K04343 strB; streptomycin 6-kinase [EC:2.7.1.72]
D RF_0996 D-alanyl-D-alanine dipeptidase K08641 vanX; zinc D-Ala-D-Ala dipeptidase [EC:3.4.13.22]
D RF_0643 RND efflux system, outer membrane protein K18139 oprM; outer membrane protein, multidrug efflux system
D RF_0985 tolC; Type I secretion outer membrane protein, TolC family K12340 tolC; outer membrane protein
C 00535 Proteoglycans
C 00536 Glycosaminoglycan binding proteins [BR:rfe00536]
D RF_p56 Hyaluronidase K01197 hya; hyaluronoglucosaminidase [EC:3.2.1.35]
D RF_pd56 Hyaluronidase K01197 hya; hyaluronoglucosaminidase [EC:3.2.1.35]
C 00537 Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:rfe00537]
D RF_p56 Hyaluronidase K01197 hya; hyaluronoglucosaminidase [EC:3.2.1.35]
D RF_pd56 Hyaluronidase K01197 hya; hyaluronoglucosaminidase [EC:3.2.1.35]
C 04091 Lectins
C 04990 Domain-containing proteins not elsewhere classified
B
B 09185 Viral protein families
C 03200 Viral proteins
C 03210 Viral fusion proteins
B
B 09184 RNA family
C 03100 Non-coding RNAs [BR:rfe03100]
D RF_RNA21 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D RF_RNA27 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D RF_RNA36 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D RF_RNA24 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D RF_RNA26 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D RF_RNA31 tRNA-Asn K14220 tRNA-Asn; tRNA Asn
D RF_RNA18 tRNA-Asp K14221 tRNA-Asp; tRNA Asp
D RF_RNA15 tRNA-Cys K14222 tRNA-Cys; tRNA Cys
D RF_RNA25 tRNA-Gln K14223 tRNA-Gln; tRNA Gln
D RF_RNA02 tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D RF_RNA10 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D RF_RNA29 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D RF_RNA07 tRNA-His K14226 tRNA-His; tRNA His
D RF_RNA17 tRNA-Ile K14227 tRNA-Ile; tRNA Ile
D RF_RNA08 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D RF_RNA38 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D RF_RNA28 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D RF_RNA16 tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D RF_RNA30 tRNA-Met K14230 tRNA-Met; tRNA Met
D RF_RNA04 tRNA-Met K14230 tRNA-Met; tRNA Met
D RF_RNA34 tRNA-Met K14230 tRNA-Met; tRNA Met
D RF_RNA01 tRNA-Phe K14231 tRNA-Phe; tRNA Phe
D RF_RNA35 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D RF_RNA23 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D RF_RNA22 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D RF_RNA05 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D RF_RNA32 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D RF_RNA39 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D RF_RNA03 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D RF_RNA33 tRNA-Trp K14235 tRNA-Trp; tRNA Trp
D RF_RNA09 tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr
D RF_RNA20 tRNA-Val K14237 tRNA-Val; tRNA Val
D RF_RNA11 tRNA-Val K14237 tRNA-Val; tRNA Val
D RF_RNA14 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D RF_RNA12 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D RF_RNA13 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D RF_RNA37 signal recognition particle RNA (4.5S RNA) K01983 ffs; SRP RNA
D RF_RNA19 RNA subunit (M1 RNA) of ribonuclease P K01978 rnpB; M1 RNA
D RF_RNA06 tmRNA precursor K15035 ssrA; transfer-messenger RNA
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A09190 Not Included in Pathway or Brite
B
B 09191 Unclassified: metabolism
C 99980 Enzymes with EC numbers
D RF_0036 Pyrroloquinoline quinone (Coenzyme PQQ) biosynthesis protein C K06137 pqqC; pyrroloquinoline-quinone synthase [EC:1.3.3.11]
D RF_0198 bcp; Bacterioferritin comigratory protein K03564 BCP; thioredoxin-dependent peroxiredoxin [EC:1.11.1.24]
D RF_0874 unknown K05916 hmp; nitric oxide dioxygenase [EC:1.14.12.17]
D RF_0576 cutE; Apolipoprotein N-acyltransferase K03820 lnt; apolipoprotein N-acyltransferase [EC:2.3.1.269]
D RF_0133 lgt; Prolipoprotein diacylglyceryl transferase K13292 lgt; phosphatidylglycerol---prolipoprotein diacylglyceryl transferase [EC:2.5.1.145]
D RF_0001 Uncharacterized protein K09773 ppsR; [pyruvate, water dikinase]-phosphate phosphotransferase / [pyruvate, water dikinase] kinase [EC:2.7.4.28 2.7.11.33]
D RF_0236 tatD; Putative deoxyribonuclease, hydrolase K03424 tatD; TatD DNase family protein [EC:3.1.21.-]
D RF_0730 def2; Polypeptide deformylase K01462 PDF; peptide deformylase [EC:3.5.1.88]
D RF_0324 def1; Polypeptide deformylase K01462 PDF; peptide deformylase [EC:3.5.1.88]
D RF_0124 def3; Polypeptide deformylase K01462 PDF; peptide deformylase [EC:3.5.1.88]
C 99981 Carbohydrate metabolism
C 99982 Energy metabolism
D RF_1064 fdxB; Ferredoxin K04755 fdx; ferredoxin, 2Fe-2S
D RF_1315 fdxA; Ferredoxin K05524 fdxA; ferredoxin
D RF_0844 iscU; FeS cluster assembly scaffold IscU K04488 iscU; nitrogen fixation protein NifU and related proteins
C 99983 Lipid metabolism
C 99984 Nucleotide metabolism
C 99985 Amino acid metabolism
C 99986 Glycan metabolism
C 99987 Cofactor metabolism
D RF_0244 ubiB; 2-polyprenylphenol 6-hydroxylase K03688 ubiB; ubiquinone biosynthesis protein
D RF_0425 unknown K18587 COQ9; ubiquinone biosynthesis protein COQ9
D RF_1113 unknown K18588 COQ10; coenzyme Q-binding protein COQ10
C 99988 Secondary metabolism
C 99999 Others
D RF_1189 Serine esterase K06999 K06999; phospholipase/carboxylesterase
B
B 09192 Unclassified: genetic information processing
C 99973 Transcription
D RF_0262 cspA; Cold shock-like protein K03704 cspA; cold shock protein
C 99974 Translation
C 99975 Protein processing
D RF_1336 tig; Trigger factor K03545 tig; trigger factor
D RF_0661 smpB; tmRNA-binding protein K03664 smpB; SsrA-binding protein
D RF_0518 Mg chelatase-related protein K07391 comM; magnesium chelatase family protein
C 99976 Replication and repair
D RF_1310 radC; DNA repair protein RadC K03630 radC; DNA repair protein RadC
D RF_0225 Uncharacterized protein K09760 rmuC; DNA recombination protein RmuC
D RF_0424 Excinuclease ABC, C subunit, N-terminal K07461 K07461; putative endonuclease
D RF_1058 Excinuclease ABC, C subunit, N-terminal K07461 K07461; putative endonuclease
D RF_0946 Excinuclease ABC, C subunit, N-terminal K07461 K07461; putative endonuclease
D RF_1008 Endo/excinuclease amino terminal domain protein K07461 K07461; putative endonuclease
D RF_0531 dprA; Putatie DNA processing protein DprA K04096 smf; DNA processing protein
D RF_p57 Transposase K07486 K07486; transposase
D RF_pd57 Transposase K07486 K07486; transposase
D RF_0049 Transposase K07493 K07493; putative transposase
D RF_0320 Transposase K07493 K07493; putative transposase
D RF_0321 Transposase K07493 K07493; putative transposase
D RF_0101 Transposase K07493 K07493; putative transposase
D RF_0103 Transposase K07493 K07493; putative transposase
D RF_0105 Transposase K07493 K07493; putative transposase
D RF_0106 Transposase K07493 K07493; putative transposase
D RF_0065 Transposase K07493 K07493; putative transposase
D RF_0158 Transposase K07493 K07493; putative transposase
D RF_0159 Transposase K07493 K07493; putative transposase
D RF_0392 Transposase K07493 K07493; putative transposase
D RF_0393 Transposase K07493 K07493; putative transposase
D RF_0880 Transposase K07493 K07493; putative transposase
D RF_0881 Transposase K07493 K07493; putative transposase
D RF_1071 Transposase K07493 K07493; putative transposase
D RF_1072 Transposase K07493 K07493; putative transposase
D RF_0926 Transposase K07493 K07493; putative transposase
D RF_0927 Transposase K07493 K07493; putative transposase
D RF_0920 Transposase K07493 K07493; putative transposase
D RF_0921 Transposase K07493 K07493; putative transposase
D RF_1053 Transposase K07493 K07493; putative transposase
D RF_1054 Transposase K07493 K07493; putative transposase
D RF_0930 Transposase K07493 K07493; putative transposase
D RF_0931 Transposase K07493 K07493; putative transposase
D RF_0998 Transposase K07493 K07493; putative transposase
D RF_0999 Transposase K07493 K07493; putative transposase
D RF_1204 Transposase K07493 K07493; putative transposase
D RF_1205 Transposase K07493 K07493; putative transposase
D RF_1181 Transposase K07493 K07493; putative transposase
D RF_1182 Transposase K07493 K07493; putative transposase
D RF_0587 Transposase K07493 K07493; putative transposase
D RF_0588 Transposase K07493 K07493; putative transposase
D RF_1139 Transposase K07493 K07493; putative transposase
D RF_1140 Transposase K07493 K07493; putative transposase
D RF_1392 Transposase K07493 K07493; putative transposase
D RF_1393 Transposase K07493 K07493; putative transposase
D RF_p30 Transposase K07493 K07493; putative transposase
D RF_p54 Transposase K07493 K07493; putative transposase
D RF_p55 Transposase K07493 K07493; putative transposase
D RF_pd54 Transposase K07493 K07493; putative transposase
D RF_pd55 Transposase K07493 K07493; putative transposase
D RF_p31 Transposase K07493 K07493; putative transposase
D RF_0383 Transposase K07494 K07494; putative transposase
C 99979 Viral proteins
C 99998 Others
D RF_1365 Conserved hypothetical protein K09747 ebfC; nucleoid-associated protein EbfC
B
B 09193 Unclassified: signaling and cellular processes
C 99977 Transport
D RF_0497 atrC1; Cationic amino acid transporter-1 K03294 TC.APA; basic amino acid/polyamine antiporter, APA family
D RF_0841 potE; Putrescine-ornithine antiporter K03294 TC.APA; basic amino acid/polyamine antiporter, APA family
D RF_0640 RND family efflux transporter K03296 TC.HAE1; hydrophobic/amphiphilic exporter-1 (mainly G- bacteria), HAE1 family
D RF_0641 RND family efflux transporter K03296 TC.HAE1; hydrophobic/amphiphilic exporter-1 (mainly G- bacteria), HAE1 family
D RF_1109 acrF; Hydrophobe/amphiphile efflux-1 HAE1 family protein K03296 TC.HAE1; hydrophobic/amphiphilic exporter-1 (mainly G- bacteria), HAE1 family
D RF_0122 tlc1; ADP,ATP carrier protein K03301 TC.AAA; ATP:ADP antiporter, AAA family
D RF_0724 tlc4; ADP,ATP carrier protein K03301 TC.AAA; ATP:ADP antiporter, AAA family
D RF_0161 tlc5; ADP,ATP carrier protein K03301 TC.AAA; ATP:ADP antiporter, AAA family
C 99978 Cell growth
D RF_0613 ispZ; Intracellular septation protein A K06190 ispZ; intracellular septation protein
D RF_0359 Site-specific recombinases K06400 spoIVCA; site-specific DNA recombinase
C 99993 Cell motility
D RF_0416 unknown K07343 tfoX; DNA transformation protein and related proteins
C 99995 Signaling proteins
D RF_1018 typA; GTP-binding protein TypA K06207 typA; GTP-binding protein
C 99992 Structural proteins
D RF_0076 vacJ; VacJ lipoprotein precursor K04754 mlaA; phospholipid-binding lipoprotein MlaA
D RF_0060 ompW; OmpW family outer-membrane protein K07275 ompW; outer membrane protein
D RF_0961 ccmE; Cytochrome c-type biogenesis protein CcmE K02197 ccmE; cytochrome c-type biogenesis protein CcmE
C 99994 Others
D RF_1252 terC; Tellurium resistance protein TerC K05794 terC; tellurite resistance protein TerC
D RF_1095 cutA; Periplasmic divalent cation tolerance protein K03926 cutA; periplasmic divalent cation tolerance protein
D RF_0522 cyaY; CyaY protein K06202 cyaY; iron-sulfur cluster assembly protein CyaY
B
B 09194 Poorly characterized
C 99996 General function prediction only
D RF_1086 chaB; Cation transport regulator ChaB K06197 chaB; cation transport regulator
D RF_0009 Predicted esterase of the alpha-beta hydrolase superfamily K07001 K07001; NTE family protein
D RF_0743 Predicted esterase of the alpha-beta hydrolase superfamily K07001 K07001; NTE family protein
D RF_0111 iscA1; Iron-sulfur cluster assembly accessory protein K15724 erpA; iron-sulfur cluster insertion protein
D RF_0727 rbn; Ribonuclease BN, putative K07058 K07058; membrane protein
D RF_1164 Predicted sulfurtransferase K07146 K07146; UPF0176 protein
C 99997 Function unknown
D RF_0987 Ankyrin repeat K06867 K06867; uncharacterized protein
D RF_0314 Ankyrin repeat K06867 K06867; uncharacterized protein
D RF_1306 Ankyrin repeat K06867 K06867; uncharacterized protein
D RF_0950 Ankyrin repeat K06867 K06867; uncharacterized protein
D RF_1158 unknown K06867 K06867; uncharacterized protein
D RF_1087 Ankyrin repeat K06867 K06867; uncharacterized protein
D RF_1099 Ankyrin repeat K06867 K06867; uncharacterized protein
D RF_p42 Ankyrin repeat K06867 K06867; uncharacterized protein
D RF_pd42 Ankyrin repeat K06867 K06867; uncharacterized protein
D RF_1289 unknown K06884 K06884; uncharacterized protein
D RF_0546 Predicted hydrolases or acyltransferases K06889 K06889; uncharacterized protein
D RF_1134 Integral membrane protein K06890 K06890; uncharacterized protein
D RF_0828 unknown K07018 K07018; uncharacterized protein
D RF_0940 NT (nucleotidyltransferase) domain and HEPN (higher eukarytoes and prokaryotes nucleotide-binding) domain K07076 K07076; uncharacterized protein
D RF_1280 NT (nucleotidyltransferase) domain and HEPN (higher eukarytoes and prokaryotes nucleotide-binding) domain K07076 K07076; uncharacterized protein
D RF_1162 NT (nucleotidyltransferase) domain and HEPN (higher eukarytoes and prokaryotes nucleotide-binding) domain K07076 K07076; uncharacterized protein
D RF_1066 imp; TRAP-type uncharacterized transport system K07080 K07080; uncharacterized protein
D RF_0247 Predicted ATPase K07133 K07133; uncharacterized protein
D RF_1277 Predicted ATPase K07133 K07133; uncharacterized protein
D RF_1227 Predicted ATPase K07133 K07133; uncharacterized protein
D RF_0226 Predicted ATPase K07133 K07133; uncharacterized protein
D RF_0562 Conserved hypothetical protein K08998 K08998; uncharacterized protein
D RF_1332 Conserved hypothetical protein K09131 K09131; uncharacterized protein
D RF_1110 Uncharacterized protein K09779 K09779; uncharacterized protein
D RF_0168 unknown K09803 K09803; uncharacterized protein
D RF_0237 unknown K09805 K09805; uncharacterized protein
D RF_0769 unknown K09861 K09861; uncharacterized protein
D RF_0695 unknown K09973 K09973; uncharacterized protein
D RF_0179 unknown K09985 K09985; uncharacterized protein
D RF_0058 unknown K09987 K09987; uncharacterized protein
D RF_0986 unknown K09991 K09991; uncharacterized protein
D RF_1170 unknown K07276 K07276; uncharacterized protein
!
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#[ KO | BRITE | KEGG2 | KEGG ]
#Last updated: April 24, 2024