+E Messenger RNA Biogenesis KO
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Messenger RNA Biogenesis - Serinus canaria (common canary)
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AEukaryotic type
B mRNA processing factors
C 5' end processing
D Capping factors
E 103826451 mRNA cap guanine-N7 methyltransferase K00565 RNMT; mRNA (guanine-N7-)-methyltransferase [EC:2.1.1.56]
E 103819287 RNGTT; mRNA-capping enzyme isoform X1 K13917 RNGTT; mRNA-capping enzyme [EC:2.7.7.50 3.6.1.74]
E 103819502 CDK7; cyclin-dependent kinase 7 isoform X1 K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
E 103817971 CMTR1; cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 K14589 CMTR1; cap1 methyltransferase [EC:2.1.1.57]
E 103816673 CMTR2; cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2 K14590 CMTR2; cap2 methyltransferase [EC:2.1.1.296]
E 103816042 RAMAC; RNA guanine-N7 methyltransferase activating subunit isoform X2 K18708 FAM103A1; RNMT-activating mini protein
D Cap binding complex
E 103821859 NCBP1; nuclear cap-binding protein subunit 1 K12882 NCBP1; nuclear cap-binding protein subunit 1
E 103815404 NCBP2; nuclear cap-binding protein subunit 2 isoform X2 K12883 NCBP2; nuclear cap-binding protein subunit 2
E 103824214 nuclear cap-binding protein subunit 2 K12883 NCBP2; nuclear cap-binding protein subunit 2
C 3' end processing
D Pre-mRNA cleavage factor Im (CFIm)
E 103813677 CPSF6; cleavage and polyadenylation specificity factor subunit 6 isoform X1 K14398 CPSF6_7; cleavage and polyadenylation specificity factor subunit 6/7
E 103822270 CPSF7; cleavage and polyadenylation specificity factor subunit 7 K14398 CPSF6_7; cleavage and polyadenylation specificity factor subunit 6/7
D Pre-mRNA cleavage factor IIm (CFIIm)
E 103822156 polyribonucleotide 5'-hydroxyl-kinase Clp1 K14399 CLP1; polyribonucleotide 5'-hydroxyl-kinase [EC:2.7.1.78]
E 103812500 PCF11; pre-mRNA cleavage complex 2 protein Pcf11 K14400 PCF11; pre-mRNA cleavage complex 2 protein Pcf11
D Cleavage and polyadenylation specificity factor (CPSF) complex
E 103826468 CPSF2; cleavage and polyadenylation specificity factor subunit 2 K14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2
E 103820423 CPSF3; cleavage and polyadenylation specificity factor subunit 3 isoform X1 K14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]
E 103817613 CPSF4; cleavage and polyadenylation specificity factor subunit 4 K14404 CPSF4; cleavage and polyadenylation specificity factor subunit 4
E 103819959 CPSF4L; putative cleavage and polyadenylation specificity factor subunit 4-like protein isoform X1 K14404 CPSF4; cleavage and polyadenylation specificity factor subunit 4
E 103826187 FIP1L1; pre-mRNA 3'-end-processing factor FIP1 K14405 FIP1L1; pre-mRNA 3'-end-processing factor FIP1
E 103816502 pre-mRNA 3'-end-processing factor FIP1-like K14405 FIP1L1; pre-mRNA 3'-end-processing factor FIP1
E 103815523 WDR33; pre-mRNA 3' end processing protein WDR33 isoform X1 K15542 PFS2; polyadenylation factor subunit 2
E 103824293 WDR82; WD repeat-containing protein 82 K14962 WDR82; COMPASS component SWD2
E 103817249 PPP1CB; serine/threonine-protein phosphatase PP1-beta catalytic subunit K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E 103818147 PPP1CC; serine/threonine-protein phosphatase PP1-gamma catalytic subunit K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E 103822255 PPP1CA; serine/threonine-protein phosphatase PP1-alpha catalytic subunit K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E 103820799 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 K15544 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16]
D Cleavage stimulation factor (CSTF) complex
E 103818757 CSTF1; cleavage stimulation factor subunit 1 isoform X1 K14406 CSTF1; cleavage stimulation factor subunit 1
E 103816457 CSTF2; cleavage stimulation factor subunit 2 isoform X1 K14407 CSTF2; cleavage stimulation factor subunit 2
E 103822101 CSTF3; cleavage stimulation factor subunit 3 K14408 CSTF3; cleavage stimulation factor subunit 3
D U7-dependent histone pre-mRNA processing factors
E 103818813 SNRPB; small nuclear ribonucleoprotein-associated proteins B and B' K11086 SNRPB; small nuclear ribonucleoprotein B and B'
E 103818011 SNRPD3; small nuclear ribonucleoprotein Sm D3 K11088 SNRPD3; small nuclear ribonucleoprotein D3
E 103824503 SNRPE; small nuclear ribonucleoprotein E K11097 SNRPE; small nuclear ribonucleoprotein E
E 103813641 SNRPF; small nuclear ribonucleoprotein F K11098 SNRPF; small nuclear ribonucleoprotein F
E 103824655 SNRPG; small nuclear ribonucleoprotein G K11099 SNRPG; small nuclear ribonucleoprotein G
E 103822589 LSM10; U7 snRNA-associated Sm-like protein LSm10 K25591 LSM10; U7 snRNA-associated Sm-like protein LSm10
E 103817500 LSM11; U7 snRNA-associated Sm-like protein LSm11 K25592 LSM11; U7 snRNA-associated Sm-like protein LSm11
E 103826468 CPSF2; cleavage and polyadenylation specificity factor subunit 2 K14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2
E 103820423 CPSF3; cleavage and polyadenylation specificity factor subunit 3 isoform X1 K14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]
E 103816457 CSTF2; cleavage stimulation factor subunit 2 isoform X1 K14407 CSTF2; cleavage stimulation factor subunit 2
E 103823672 SLBP; histone RNA hairpin-binding protein K18710 SLBP; histone RNA hairpin-binding protein
E 103826116 uncharacterized protein LOC103826116 K18710 SLBP; histone RNA hairpin-binding protein
E 103819169 CASP8AP2; CASP8-associated protein 2 K25593 CASP8AP2; CASP8-associated protein 2
D DRB sensitivity inducing factor (DSIF) complex
E 103820039 SUPT4H1; transcription elongation factor SPT4 K15171 SUPT4H1; transcription elongation factor SPT4
D N6-methyltransferase complex
E 103821400 METTL14; N6-adenosine-methyltransferase non-catalytic subunit K23960 METTL14; mRNA m6A methyltransferase non-catalytic subunit
E 103826913 METTL4; methyltransferase-like protein 4 isoform X1 K24174 METTL4; N(6)-adenine-specific DNA methyltransferase [EC:2.1.1.72]
E 103827124 METTL16; RNA N6-adenosine-methyltransferase METTL16 K11393 METTL16; U6 snRNA m6A methyltransferase [EC:2.1.1.346]
E 103820563 WTAP; pre-mRNA-splicing regulator WTAP K22824 WTAP; pre-mRNA-splicing regulator WTAP
E 103813578 VIRMA; protein virilizer homolog K22910 VIRMA; protein virilizer
E 103816962 RBM15B; LOW QUALITY PROTEIN: putative RNA-binding protein 15B K13190 RBM15; RNA-binding protein 15
E 103822419 RBM15; RNA-binding protein 15 K13190 RBM15; RNA-binding protein 15
E 103827417 ZC3H13; zinc finger CCCH domain-containing protein 13 isoform X1 K22909 ZC3H13; zinc finger CCCH domain-containing protein 13
E 103813512 CBLL1; E3 ubiquitin-protein ligase Hakai isoform X3 K15685 CBLL1; E3 ubiquitin-protein ligase Hakai [EC:2.3.2.27]
D Poly(A) addition factors
E 103819322 PAPOLG; poly(A) polymerase gamma isoform X1 K14376 PAP; poly(A) polymerase [EC:2.7.7.19]
E 103826440 PAPOLA; poly(A) polymerase alpha isoform X1 K14376 PAP; poly(A) polymerase [EC:2.7.7.19]
E 103819508 TENT2; poly(A) RNA polymerase GLD2 K14079 PAPD4; poly(A) RNA polymerase GLD2 [EC:2.7.7.19]
D Negative regulators of mRNA 3' end processing
E 103814754 BARD1; BRCA1-associated RING domain protein 1 isoform X1 K10683 BARD1; BRCA1-associated RING domain protein 1
E 103812275 RBM26; RNA-binding protein 26 isoform X2 K13192 RBM26; RNA-binding protein 26
E 103816808 FTO; alpha-ketoglutarate-dependent dioxygenase FTO isoform X3 K19469 FTO; mRNA N6-methyladenine demethylase [EC:1.14.11.53]
E 103817835 ALKBH5; RNA demethylase ALKBH5 K10767 ALKBH5; mRNA N6-methyladenine demethylase [EC:1.14.11.53]
E 103820769 TARDBP; TAR DNA-binding protein 43 K23600 TARDBP; TAR DNA-binding protein 43
C Other processing factors
D 103820167 DHX40; LOW QUALITY PROTEIN: probable ATP-dependent RNA helicase DHX40 K18711 DHX40; ATP-dependent RNA helicase DHX40 [EC:5.6.2.6]
D 103813581 KIN; DNA/RNA-binding protein KIN17 isoform X1 K13102 KIN; DNA/RNA-binding protein KIN17
D 103814692 METTL8; methyltransferase-like protein 8 isoform X1 K24975 METTL8; mRNA N(3)-methylcytidine methyltransferase METTL8 [EC:2.1.1.-]
D 103817738 METTL22; methyltransferase-like protein 22 isoform X1 K23040 METTL22; methyltransferase-like protein 22 [EC:2.1.1.-]
D 103819606 TENT5A; terminal nucleotidyltransferase 5A K23033 TENT5A_B; terminal nucleotidyltransferase 5A/B [EC:2.7.7.-]
D 103823592 TENT5B; LOW QUALITY PROTEIN: terminal nucleotidyltransferase 5B K23033 TENT5A_B; terminal nucleotidyltransferase 5A/B [EC:2.7.7.-]
D 103827129 TENT5C; terminal nucleotidyltransferase 5C isoform X1 K23034 TENT5C; terminal nucleotidyltransferase 5C [EC:2.7.7.19]
D 103816440 TENT5D; terminal nucleotidyltransferase 5D K23035 TENT5D; terminal nucleotidyltransferase 5D [EC:2.7.7.19]
D 103826485 ZC3H14; zinc finger CCCH domain-containing protein 14 K23038 ZC3H14; zinc finger CCCH domain-containing protein 14
B mRNA surveillance and transport factors
C Transport factors
D EJC complex
E 103825232 RBM8A; RNA-binding protein 8A K12876 RBM8A; RNA-binding protein 8A
E 103815035 MAGOH; protein mago nashi homolog K12877 MAGOH; protein mago nashi
E 103819915 LOW QUALITY PROTEIN: THO complex subunit 4 K12881 THOC4; THO complex subunit 4
E 115484521 LOW QUALITY PROTEIN: THO complex subunit 4-like K12881 THOC4; THO complex subunit 4
E 103821332 EIF4A3; eukaryotic initiation factor 4A-III K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]
E 103817172 CCDC174; coiled-coil domain-containing protein 174 K25178 CCDC174; coiled-coil domain-containing protein 174
E 103821751 CASC3; protein CASC3 K14323 CASC3; protein CASC3
E 103827315 SAP18; histone deacetylase complex subunit SAP18 K14324 SAP18; histone deacetylase complex subunit SAP18
E 103826539 PNN; pinin K13114 PNN; pinin
E 103824362 RNPS1; RNA-binding protein with serine-rich domain 1 K14325 RNPS1; RNA-binding protein with serine-rich domain 1
E 103823569 SRRM1; LOW QUALITY PROTEIN: serine/arginine repetitive matrix protein 1 K13171 SRRM1; serine/arginine repetitive matrix protein 1
D TREX complex
E 103815984 THOC1; THO complex subunit 1 isoform X1 K12878 THOC1; THO complex subunit 1
E 103816527 THOC2; THO complex subunit 2 K12879 THOC2; THO complex subunit 2
E 103817351 THOC3; THO complex subunit 3 K12880 THOC3; THO complex subunit 3
E 103819915 LOW QUALITY PROTEIN: THO complex subunit 4 K12881 THOC4; THO complex subunit 4
E 115484521 LOW QUALITY PROTEIN: THO complex subunit 4-like K12881 THOC4; THO complex subunit 4
E 103817988 THOC5; THO complex subunit 5 homolog isoform X2 K13174 THOC5; THO complex subunit 5
E 103817074 THOC7; THO complex subunit 7 homolog isoform X1 K13176 THOC7; THO complex subunit 7
D TREX-2 complex
E 103812398 PCID2; PCI domain-containing protein 2 isoform X2 K23801 PCID2; nuclear mRNA export protein PCID2/THP1
E 103814125 ENY2; transcription and mRNA export factor ENY2 K11368 ENY2; enhancer of yellow 2 transcription factor
E 103816491 centrin-2 K10840 CETN2; centrin-2
E 103820994 CETN3; centrin-3 K16466 CETN3; centrin-3
E 103814769 MCM3AP; germinal-center associated nuclear protein K24317 MCM3AP; germinal-center associated nuclear protein [EC:2.3.1.48]
D Nuclear pore complex
E 103814805 TPR; nucleoprotein TPR isoform X3 K09291 TPR; nucleoprotein TPR
E 103818751 RAE1; mRNA export factor K14298 RAE1; mRNA export factor
E 103824153 SEC13; protein SEC13 homolog K14004 SEC13; protein transport protein SEC13
E 103819652 NUP37; nucleoporin Nup37 K14302 NUP37; nuclear pore complex protein Nup37
E 103819994 NUP85; nuclear pore complex protein Nup85 K14304 NUP85; nuclear pore complex protein Nup85
E 103820567 NUP43; nucleoporin Nup43 K14305 NUP43; nuclear pore complex protein Nup43
E 103820446 NUP50; nuclear pore complex protein Nup50 K14295 NUP50; nuclear pore complex protein Nup50
E 103823429 NUP54; nucleoporin p54 isoform X2 K14308 NUP54; nuclear pore complex protein Nup54
E 103824266 LOW QUALITY PROTEIN: nuclear pore glycoprotein p62-like K14306 NUP62; nuclear pore complex protein Nup62
E 103824264 NUP62CL; nucleoporin-62 C-terminal-like protein isoform X2 K14306 NUP62; nuclear pore complex protein Nup62
E 103820064 NUP88; nuclear pore complex protein Nup88 K14318 NUP88; nuclear pore complex protein Nup88
E 103816659 NUP93; nuclear pore complex protein Nup93 isoform X3 K14309 NUP93; nuclear pore complex protein Nup93
E 103824472 NUP98; nuclear pore complex protein Nup98-Nup96 K14297 NUP98; nuclear pore complex protein Nup98-Nup96
E 103813453 NUP107; nuclear pore complex protein Nup107 K14301 NUP107; nuclear pore complex protein Nup107
E 103818505 NUP133; nuclear pore complex protein Nup133 K14300 NUP133; nuclear pore complex protein Nup133
E 103819017 NUP188; nucleoporin NUP188 homolog K14311 NUP188; nuclear pore complex protein Nup188
E 103813350 NUP153; nuclear pore complex protein Nup153 isoform X1 K14296 NUP153; nuclear pore complex protein Nup153
E 103821069 NUP155; nuclear pore complex protein Nup155 K14312 NUP155; nuclear pore complex protein Nup155
E 103822297 NUP160; nuclear pore complex protein Nup160 K14303 NUP160; nuclear pore complex protein Nup160
E 103814564 NUP35; nucleoporin NUP35 isoform X1 K14313 NUP35; nuclear pore complex protein Nup53
E 103813374 NUP205; nuclear pore complex protein Nup205 K14310 NUP205; nuclear pore complex protein Nup205
E 103817108 NUP210; nuclear pore membrane glycoprotein 210 isoform X1 K14314 NUP210; nuclear pore complex protein Nup210
E 103818993 NUP214; nuclear pore complex protein Nup214 isoform X1 K14317 NUP214; nuclear pore complex protein Nup214
E 103820223 POM121; nuclear envelope pore membrane protein POM 121 K14316 POM121; nuclear pore complex protein Nup121
E 103812546 NUP58; nucleoporin p58/p45 isoform X1 K14307 NUPL1; nucleoporin p58/p45
E 103812880 nucleoporin NUP42-like K14321 NUPL2; nucleoporin-like protein 2
E 115485584 nucleoporin NUP42-like K14321 NUPL2; nucleoporin-like protein 2
E 103815038 NDC1; nucleoporin NDC1 isoform X2 K14315 NDC1; nucleoporin NDC1
E 103815864 SEH1L; nucleoporin SEH1 isoform X1 K14299 SEH1; nucleoporin SEH1
E 103812650 RGPD4; ranBP2-like and GRIP domain-containing protein 4 isoform X1 K12172 RANBP2; E3 SUMO-protein ligase RanBP2 [EC:2.3.2.-]
E 103815493 SENP2; sentrin-specific protease 2 K03345 SENP2; sentrin-specific protease 2 (axin associating molecule) [EC:3.4.22.68]
E 103820994 CETN3; centrin-3 K16466 CETN3; centrin-3
E 103819029 GLE1; nucleoporin GLE1 K18723 GLE1; nucleoporin GLE1
E 103816374 NXT2; NTF2-related export protein 2 isoform X1 K14285 NXT1_2; NTF2-related export protein 1/2
D Ran-mediated transport factors
E 103818200 RAN; GTP-binding nuclear protein Ran K07936 RAN; GTP-binding nuclear protein Ran
E 103816257 ANP32A; acidic leucine-rich nuclear phosphoprotein 32 family member A K18646 ANP32A_C_D; acidic leucine-rich nuclear phosphoprotein 32 family member A/C/D
E 103821915 acidic leucine-rich nuclear phosphoprotein 32 family member B isoform X1 K18647 ANP32B; acidic leucine-rich nuclear phosphoprotein 32 family member B
E 103821886 ELAVL1; ELAV-like protein 1 isoform X2 K13088 ELAVL1; ELAV-like protein 1
E 103815004 ELAVL4; ELAV-like protein 4 isoform X2 K13208 ELAVL2_3_4; ELAV like protein 2/3/4
E 103821822 ELAVL2; ELAV-like protein 2 isoform X3 K13208 ELAVL2_3_4; ELAV like protein 2/3/4
E 103817356 FAF2; FAS-associated factor 2 K18726 FAF2; FAS-associated factor 2
E 103822935 VCP; LOW QUALITY PROTEIN: transitional endoplasmic reticulum ATPase K13525 VCP; transitional endoplasmic reticulum ATPase
E 103824680 transitional endoplasmic reticulum ATPase-like K13525 VCP; transitional endoplasmic reticulum ATPase
E 103826823 VCPKMT; protein-lysine methyltransferase METTL21D K21806 VCPKMT; protein N-lysine methyltransferase METTL21D [EC:2.1.1.-]
E 103819237 XPO1; exportin-1 K14290 XPO1; exportin-1
E 103824525 XPO7; exportin-7 K18460 XPO7; exportin-7
E 103813293 RANGAP1; ran GTPase-activating protein 1 K14319 RANGAP1; Ran GTPase-activating protein 1
E 103820264 TAF15; TATA-binding protein-associated factor 2N isoform X1 K14651 TAF15; transcription initiation factor TFIID subunit 15
D eIF4F and regulatory proteins
E 103817506 EIF4E1B; eukaryotic translation initiation factor 4E type 1B isoform X2 K03259 EIF4E; translation initiation factor 4E
E 103826035 EIF4E; eukaryotic translation initiation factor 4E isoform X2 K03259 EIF4E; translation initiation factor 4E
E 103815612 EIF4E2; eukaryotic translation initiation factor 4E type 2 isoform X1 K03259 EIF4E; translation initiation factor 4E
E 103815326 EIF4A2; eukaryotic initiation factor 4A-II K03257 EIF4A; translation initiation factor 4A
E 103827041 EIF4G2; eukaryotic translation initiation factor 4 gamma 2 isoform X1 K03260 EIF4G; translation initiation factor 4G
E 103815334 EIF4G1; eukaryotic translation initiation factor 4 gamma 1 isoform X1 K03260 EIF4G; translation initiation factor 4G
E 103820961 EIF4G3; LOW QUALITY PROTEIN: eukaryotic translation initiation factor 4 gamma 3 K03260 EIF4G; translation initiation factor 4G
E 103823897 EIF4B; eukaryotic translation initiation factor 4B K03258 EIF4B; translation initiation factor 4B
E 103820241 EIF4H; eukaryotic translation initiation factor 4H isoform X1 K24086 EIF4H; translation initiation factor 4H
E 103822697 EIF4EBP1; eukaryotic translation initiation factor 4E-binding protein 1 isoform X2 K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
E 103823741 EIF4EBP2; eukaryotic translation initiation factor 4E-binding protein 2 K18644 EIF4EBP2; eukaryotic translation initiation factor 4E binding protein 2
E 103818025 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter isoform X1 K18728 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter
E 103826905 ANGEL1; protein angel homolog 1 K18729 ANGEL; protein angel
E 103821513 ANGEL2; protein angel homolog 2 K18729 ANGEL; protein angel
E 103816358 FMR1; synaptic functional regulator FMR1 isoform X1 K15516 FMR; fragile X mental retardation protein
E 103815315 FXR1; fragile X mental retardation syndrome-related protein 1 isoform X2 K15516 FMR; fragile X mental retardation protein
E 103812334 CYFIP1; cytoplasmic FMR1-interacting protein 1 isoform X1 K05749 CYFIP; cytoplasmic FMR1 interacting protein
E 103817337 CYFIP2; cytoplasmic FMR1-interacting protein 2 isoform X1 K05749 CYFIP; cytoplasmic FMR1 interacting protein
E 103817328 GEMIN5; gem-associated protein 5 K13133 GEMIN5; gem associated protein 5
E 103823692 TACC3; transforming acidic coiled-coil-containing protein 3 K14283 TACC3; transforming acidic coiled-coil-containing protein 3
E 103815937 CPEB1; cytoplasmic polyadenylation element-binding protein 1 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 103813908 CPEB3; cytoplasmic polyadenylation element-binding protein 3 isoform X3 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 103826140 CPEB2; LOW QUALITY PROTEIN: cytoplasmic polyadenylation element-binding protein 2 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 103824097 CPEB4; cytoplasmic polyadenylation element-binding protein 4 isoform X2 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 103815775 DDX3X; ATP-dependent RNA helicase DDX3X K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]
E 103815465 GIGYF2; GRB10-interacting GYF protein 2 isoform X1 K18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein
E 103813885 PABPC1; polyadenylate-binding protein 1 K13126 PABPC; polyadenylate-binding protein
E 103818799 PABPC1L; polyadenylate-binding protein 1-like K13126 PABPC; polyadenylate-binding protein
E 103823496 PABPC4; polyadenylate-binding protein 4 K13126 PABPC; polyadenylate-binding protein
E 103824791 polyadenylate-binding protein-interacting protein 1-like isoform X1 K14322 PAIP1; polyadenylate-binding protein-interacting protein 1
E 103824184 PAIP1; polyadenylate-binding protein-interacting protein 1 isoform X1 K14322 PAIP1; polyadenylate-binding protein-interacting protein 1
E 103823786 PAIP2; polyadenylate-binding protein-interacting protein 2 K27470 PAIP2; polyadenylate-binding protein-interacting protein 2
E 103824646 PAIP2B; polyadenylate-binding protein-interacting protein 2B K27470 PAIP2; polyadenylate-binding protein-interacting protein 2
E 103822186 DEAF1; deformed epidermal autoregulatory factor 1 homolog K23041 DEAF1; deformed epidermal autoregulatory factor 1
E 103816391 MCTS1; malignant T-cell-amplified sequence 1 K07575 MCTS; malignant T-cell-amplified sequence
E 103818173 DENR; density-regulated protein K24272 DENR; density-regulated protein
D APOBEC1-ACF complex
E 103812486 C->U-editing enzyme APOBEC-1-like isoform X1 K16932 APOBEC1; C->U-editing enzyme APOBEC1 [EC:3.5.4.36]
E 103812485 C->U-editing enzyme APOBEC-1-like isoform X1 K16932 APOBEC1; C->U-editing enzyme APOBEC1 [EC:3.5.4.36]
E 103814069 A1CF; APOBEC1 complementation factor isoform X1 K24978 A1CF; APOBEC1 complementation factor
D Other transport factors
E 103814458 HNRNPA3; heterogeneous nuclear ribonucleoprotein A3 isoform X1 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 103818041 MSI1; RNA-binding protein Musashi homolog 1 K14411 MSI; RNA-binding protein Musashi
E 103820347 MSI2; RNA-binding protein Musashi homolog 2 isoform X1 K14411 MSI; RNA-binding protein Musashi
E 108963055 DAZ-associated protein 1 isoform X1 K14411 MSI; RNA-binding protein Musashi
E 103820553 HBS1L; HBS1-like protein isoform X1 K14416 HBS1; elongation factor 1 alpha-like protein
E 103821088 PELO; protein pelota homolog K06965 PELO; protein pelota
E 103816889 PABPN1L; embryonic polyadenylate-binding protein 2 K14396 PABPN1; polyadenylate-binding protein 2
E 115484225 PABPN1; polyadenylate-binding protein 2 K14396 PABPN1; polyadenylate-binding protein 2
E 103824337 ATP-dependent RNA helicase DDX19B K18655 DDX19; ATP-dependent RNA helicase DDX19/DBP5 [EC:5.6.2.7]
E 103822840 DDX25; ATP-dependent RNA helicase DDX25 K18656 DDX25; ATP-dependent RNA helicase DDX25 [EC:5.6.2.7]
E 103825292 SARNP; SAP domain-containing ribonucleoprotein K18732 SARNP; SAP domain-containing ribonucleoprotein
E 103823537 RCC1; regulator of chromosome condensation K11493 RCC1; regulator of chromosome condensation
E 103816168 LARP6; la-related protein 6 K18733 LARP6; la-related protein 6
E 103822008 la-related protein 6-like K18733 LARP6; la-related protein 6
E 103813315 POLDIP3; polymerase delta-interacting protein 3 isoform X1 K22414 POLDIP3; polymerase delta-interacting protein 3
E 103824504 ZC3H11A; zinc finger CCCH domain-containing protein 11A K22415 ZC3H11; zinc finger CCCH domain-containing protein 11
E 103815933 PATL2; protein PAT1 homolog 2 isoform X1 K24823 PATL2; protein PAT1 homolog 2
C Surveillance factors
D Surveillance complex
E 103823779 ETF1; LOW QUALITY PROTEIN: eukaryotic peptide chain release factor subunit 1 K03265 ETF1; peptide chain release factor subunit 1
E 103817712 GSPT1; eukaryotic peptide chain release factor GTP-binding subunit ERF3A isoform X1 K03267 ERF3; peptide chain release factor subunit 3
E 103824543 UPF1; regulator of nonsense transcripts 1 isoform X1 K14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3]
E 103813572 UPF2; regulator of nonsense transcripts 2 K14327 UPF2; regulator of nonsense transcripts 2
E 103816397 UPF3B; regulator of nonsense transcripts 3B K14328 UPF3; regulator of nonsense transcripts 3
E 103812387 UPF3A; regulator of nonsense transcripts 3A K14328 UPF3; regulator of nonsense transcripts 3
D Protein phosphatase 2A
E 103817471 PPP2CA; serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
E 103823422 PPP2CB; serine/threonine-protein phosphatase 2A catalytic subunit beta isoform K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
E 103817406 PPP2R2B; serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
E 103824110 PPP2R2C; protein phosphatase 2, regulatory subunit B, gamma isoform X2 K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
E 103822705 PPP2R2A; serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform isoform X1 K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
E 103814089 PPP2R2D; serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
E 103812324 PPP2R3B; serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta isoform X1 K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
E 103815474 PPP2R3A; serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
E 103826933 PPP2R3C; serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
E 103821519 PPP2R5A; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
E 103826366 PPP2R5E; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform isoform X2 K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
E 103826422 PPP2R5C; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform X1 K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
E 103821293 serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform isoform X1 K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
E 115484937 serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform-like K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
D Other surveillance factors
E 103817897 SMG1; serine/threonine-protein kinase SMG1 K08873 SMG1; serine/threonine-protein kinase SMG1 [EC:2.7.11.1]
E 103824055 SMG5; protein SMG5 K11125 SMG5; protein SMG5
E 103820119 SMG6; telomerase-binding protein EST1A isoform X1 K11124 SMG6; protein SMG6 [EC:3.1.-.-]
E 103814818 SMG7; protein SMG7 isoform X1 K14409 SMG7; protein SMG7
E 103820334 SMG8; protein SMG8 K18734 SMG8; protein SMG8
E 115484019 SMG9; LOW QUALITY PROTEIN: protein SMG9 K18735 SMG9; protein SMG9
E 103815465 GIGYF2; GRB10-interacting GYF protein 2 isoform X1 K18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein
E 103821287 SECISBP2; selenocysteine insertion sequence-binding protein 2 isoform X1 K19539 SECISBP2; selenocysteine insertion sequence-binding protein 2
E 103816022 SECISBP2L; selenocysteine insertion sequence-binding protein 2-like isoform X1 K19539 SECISBP2; selenocysteine insertion sequence-binding protein 2
E 103813266 GTPBP1; GTP-binding protein 1 isoform X1 K24887 GTPBP1; GTP-binding protein 1
C Factors involved in mRNA localization
D Cargo complex
E 103819460 PUM3; pumilio homolog 3 K14844 PUF6; pumilio homology domain family member 6
E 103816186 MYO5A; unconventional myosin-Va K10357 MYO5; myosin V
E 103816187 MYO5C; unconventional myosin-Vc K10357 MYO5; myosin V
E 103820668 MYO5B; unconventional myosin-Vb isoform X1 K10357 MYO5; myosin V
E 103816924 BICD2; protein bicaudal D homolog 2 isoform X1 K18739 BICD; protein bicaudal D
E 103819703 BICD1; protein bicaudal D homolog 1 isoform X1 K18739 BICD; protein bicaudal D
D Factors that have mRNA localization signals
E 103823197 actin, cytoplasmic type 5 K05692 ACTB_G1; actin beta/gamma 1
E 103817621 ACTB; actin, cytoplasmic 1 K05692 ACTB_G1; actin beta/gamma 1
E 103826265 MBP; myelin basic protein isoform X1 K17269 MBP; myelin basic protein
E 103812791 VIM; vimentin K07606 VIM; vimentin
E 115484025 metallothionein-1 K14739 MT1_2; metallothionein 1/2
E 103816707 MYC; myc proto-oncogene protein isoform X1 K04377 MYC; Myc proto-oncogene protein
E 103824542 LOW QUALITY PROTEIN: growth/differentiation factor 3 K05495 GDF1; growth differentiation factor 1
E 103818003 T-box-containing protein TBX6L K10180 TBX6; T-box protein 6
E 115485551 NANOS1; nanos homolog 1 K18741 NANOS1; protein nanos 1
D Trans-acting binding proteins
E 103814936 FUBP1; far upstream element-binding protein 1 isoform X3 K13210 FUBP; far upstream element-binding protein
E 103819000 FUBP3; far upstream element-binding protein 3 isoform X1 K13210 FUBP; far upstream element-binding protein
E 103818713 EEF1A2; elongation factor 1-alpha 2 K03231 EEF1A; elongation factor 1-alpha
E 103819723 EEF1A1; elongation factor 1-alpha 1 K03231 EEF1A; elongation factor 1-alpha
E 103825298 EEF1G; LOW QUALITY PROTEIN: elongation factor 1-gamma K03233 EEF1G; elongation factor 1-gamma
E 103812891 HNRNPA2B1; heterogeneous nuclear ribonucleoproteins A2/B1 isoform X1 K13158 HNRNPA2B1; heterogeneous nuclear ribonucleoprotein A2/B1
E 103823965 HAX1; HCLS1-associated protein X-1 isoform X1 K16220 HAX1; HCLS1-associated protein X-1
E 103815431 AGFG1; LOW QUALITY PROTEIN: arf-GAP domain and FG repeat-containing protein 1 K15044 AGFG1; Arf-GAP domain and FG repeats-containing protein 1
E 103812886 STAU2; double-stranded RNA-binding protein Staufen homolog 2 isoform X1 K17597 STAU; double-stranded RNA-binding protein Staufen
E 103818772 STAU1; double-stranded RNA-binding protein Staufen homolog 1 isoform X1 K17597 STAU; double-stranded RNA-binding protein Staufen
E 103813135 IGF2BP3; LOW QUALITY PROTEIN: insulin-like growth factor 2 mRNA-binding protein 3 K13197 IGF2BP3; insulin-like growth factor 2 mRNA-binding protein 3
E 103821944 PTBP1; polypyrimidine tract-binding protein 1 isoform X3 K13218 PTBP1; polypyrimidine tract-binding protein 1
E 103815937 CPEB1; cytoplasmic polyadenylation element-binding protein 1 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 103813908 CPEB3; cytoplasmic polyadenylation element-binding protein 3 isoform X3 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 103826140 CPEB2; LOW QUALITY PROTEIN: cytoplasmic polyadenylation element-binding protein 2 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 103824097 CPEB4; cytoplasmic polyadenylation element-binding protein 4 isoform X2 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
D Other mRNA localization factors
E 103816358 FMR1; synaptic functional regulator FMR1 isoform X1 K15516 FMR; fragile X mental retardation protein
E 103815315 FXR1; fragile X mental retardation syndrome-related protein 1 isoform X2 K15516 FMR; fragile X mental retardation protein
E 103812334 CYFIP1; cytoplasmic FMR1-interacting protein 1 isoform X1 K05749 CYFIP; cytoplasmic FMR1 interacting protein
E 103817337 CYFIP2; cytoplasmic FMR1-interacting protein 2 isoform X1 K05749 CYFIP; cytoplasmic FMR1 interacting protein
E 103825254 LOW QUALITY PROTEIN: poly(rC)-binding protein 2-like K13162 PCBP2; poly(rC)-binding protein 2
E 103814592 PCBP3; poly(rC)-binding protein 3 isoform X1 K21444 PCBP3_4; poly(rC)-binding protein 3/4
E 103825739 poly(rC)-binding protein 3-like isoform X1 K21444 PCBP3_4; poly(rC)-binding protein 3/4
E 103824303 PCBP4; poly(rC)-binding protein 4 isoform X2 K21444 PCBP3_4; poly(rC)-binding protein 3/4
E 103822120 CAPRIN1; caprin-1 isoform X3 K18743 CAPRIN1; caprin-1
E 103819638 CAPRIN2; caprin-2 isoform X1 K18744 CAPRIN2; caprin-2
E 103824169 YBX1; LOW QUALITY PROTEIN: nuclease-sensitive element-binding protein 1 K09276 YBX1; Y-box-binding protein 1
C mRNA cycle factors
D Common to processing body (P body) and stress granule
E 103815415 XRN1; 5'-3' exoribonuclease 1 isoform X1 K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]
E 103814724 AGO2; protein argonaute-2 K11593 ELF2C; eukaryotic translation initiation factor 2C
E 103822595 protein argonaute-3 K11593 ELF2C; eukaryotic translation initiation factor 2C
E 103822597 protein argonaute-1 isoform X2 K11593 ELF2C; eukaryotic translation initiation factor 2C
E 103822598 protein argonaute-4 K11593 ELF2C; eukaryotic translation initiation factor 2C
E 103817506 EIF4E1B; eukaryotic translation initiation factor 4E type 1B isoform X2 K03259 EIF4E; translation initiation factor 4E
E 103826035 EIF4E; eukaryotic translation initiation factor 4E isoform X2 K03259 EIF4E; translation initiation factor 4E
E 103815612 EIF4E2; eukaryotic translation initiation factor 4E type 2 isoform X1 K03259 EIF4E; translation initiation factor 4E
E 103824543 UPF1; regulator of nonsense transcripts 1 isoform X1 K14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3]
E 103815775 DDX3X; ATP-dependent RNA helicase DDX3X K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]
E 103822774 DDX6; probable ATP-dependent RNA helicase DDX6 K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7]
E 103816201 MEX3B; LOW QUALITY PROTEIN: RNA-binding protein MEX3B K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
E 103824060 MEX3A; RNA-binding protein MEX3A K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
E 103821990 MEX3D; RNA-binding protein MEX3D isoform X1 K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
E 103825027 MEX3C; RNA-binding E3 ubiquitin-protein ligase MEX3C K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
E 103824487 FASTK; LOW QUALITY PROTEIN: fas-activated serine/threonine kinase K08290 FASTK; Fas-activated serine/threonine kinase [EC:2.7.11.8]
E 103821189 LSM14A; protein LSM14 homolog A isoform X1 K18749 LSM14; protein LSM14
E 103818875 LSM14B; protein LSM14 homolog B isoform X1 K18749 LSM14; protein LSM14
E 103825254 LOW QUALITY PROTEIN: poly(rC)-binding protein 2-like K13162 PCBP2; poly(rC)-binding protein 2
E 103824169 YBX1; LOW QUALITY PROTEIN: nuclease-sensitive element-binding protein 1 K09276 YBX1; Y-box-binding protein 1
E 103813178 LIMD1; LIM domain-containing protein 1 K16682 AJUBA; LIM domain-containing protein
E 103821139 LOW QUALITY PROTEIN: Wilms tumor protein 1-interacting protein homolog K16682 AJUBA; LIM domain-containing protein
E 103812486 C->U-editing enzyme APOBEC-1-like isoform X1 K16932 APOBEC1; C->U-editing enzyme APOBEC1 [EC:3.5.4.36]
E 103812485 C->U-editing enzyme APOBEC-1-like isoform X1 K16932 APOBEC1; C->U-editing enzyme APOBEC1 [EC:3.5.4.36]
E 103823319 MOV10; helicase MOV-10 isoform X1 K18422 MOV10; helicase MOV-10 [EC:5.6.2.5]
E 103823509 PNRC2; proline-rich nuclear receptor coactivator 2 K18751 PNRC2; proline-rich nuclear receptor coactivator 2
E 103819532 TNPO1; transportin-1 isoform X1 K18752 TNPO1; transportin-1
E 103823257 transportin-1-like K18752 TNPO1; transportin-1
E 103817897 SMG1; serine/threonine-protein kinase SMG1 K08873 SMG1; serine/threonine-protein kinase SMG1 [EC:2.7.11.1]
E 103824055 SMG5; protein SMG5 K11125 SMG5; protein SMG5
E 103820119 SMG6; telomerase-binding protein EST1A isoform X1 K11124 SMG6; protein SMG6 [EC:3.1.-.-]
E 103814818 SMG7; protein SMG7 isoform X1 K14409 SMG7; protein SMG7
E 103826957 ZFP36L1; mRNA decay activator protein ZFP36L1 K18753 ZFP36L; butyrate response factor
E 103821476 ZFP36L2; LOW QUALITY PROTEIN: mRNA decay activator protein ZFP36L2 K18753 ZFP36L; butyrate response factor
E 103823587 LIN28A; protein lin-28 homolog A K18754 LIN28; protein lin-28
E 115484974 LIN28B; protein lin-28 homolog B K18754 LIN28; protein lin-28
E 103823923 HTT; huntingtin isoform X1 K04533 HD; huntingtin
E 103819705 IPO8; importin-8 isoform X1 K18755 IPO8; importin-8
E 103814051 BICC1; protein bicaudal C homolog 1 isoform X1 K18756 BICC1; protein bicaudal C
E 103814458 HNRNPA3; heterogeneous nuclear ribonucleoprotein A3 isoform X1 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 103814927 PRKACB; cAMP-dependent protein kinase catalytic subunit beta isoform X1 K04345 PKA; protein kinase A [EC:2.7.11.11]
E 103821441 LARP1B; la-related protein 1B K18757 LARP1; la-related protein 1
E 103817495 la-related protein 1 K18757 LARP1; la-related protein 1
E 103818143 ATXN2; ataxin-2 isoform X1 K23625 ATXN2_2L; ataxin 2/2L
D P-body specific factors
E 103824109 DCP2; m7GpppN-mRNA hydrolase isoform X1 K12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]
E 103817149 DCP1A; mRNA-decapping enzyme 1A isoform X2 K12610 DCP1A; mRNA-decapping enzyme 1A [EC:3.-.-.-]
E 103820521 DCP1B; mRNA-decapping enzyme 1B isoform X1 K12611 DCP1B; mRNA-decapping enzyme 1B [EC:3.-.-.-]
E 103822746 LSM1; U6 snRNA-associated Sm-like protein LSm1 K12620 LSM1; U6 snRNA-associated Sm-like protein LSm1
E 103817170 LSM3; U6 snRNA-associated Sm-like protein LSm3 K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3
E 103824704 LSM4; U6 snRNA-associated Sm-like protein LSm4 K12623 LSM4; U6 snRNA-associated Sm-like protein LSm4
E 103821492 LSM5; U6 snRNA-associated Sm-like protein LSm5 K12624 LSM5; U6 snRNA-associated Sm-like protein LSm5
E 103826076 LSM6; U6 snRNA-associated Sm-like protein LSm6 K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6
E 103821970 LSM7; U6 snRNA-associated Sm-like protein LSm7 K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7
E 103813469 LSM8; LSM8 homolog, U6 small nuclear RNA associated isoform X1 K12627 LSM8; U6 snRNA-associated Sm-like protein LSm8
E 103821298 KLC4; kinesin light chain 4 isoform X1 K10407 KLC; kinesin light chain
E 103826402 KLC1; kinesin light chain 1 isoform X1 K10407 KLC; kinesin light chain
E 103816186 MYO5A; unconventional myosin-Va K10357 MYO5; myosin V
E 103816187 MYO5C; unconventional myosin-Vc K10357 MYO5; myosin V
E 103820668 MYO5B; unconventional myosin-Vb isoform X1 K10357 MYO5; myosin V
E 103815242 tubulin alpha-3 chain isoform X1 K07374 TUBA; tubulin alpha
E 103822471 TUBAL3; tubulin alpha chain-like 3 isoform X2 K07374 TUBA; tubulin alpha
E 103824613 tubulin alpha-1 chain-like K07374 TUBA; tubulin alpha
E 103822357 tubulin alpha-8 chain K07374 TUBA; tubulin alpha
E 103820471 TUBA8; tubulin alpha-8 chain K07374 TUBA; tubulin alpha
E 103814372 LOW QUALITY PROTEIN: tubulin alpha-5 chain K07374 TUBA; tubulin alpha
E 103824612 LOW QUALITY PROTEIN: tubulin alpha-1A chain K07374 TUBA; tubulin alpha
E 108963627 tubulin alpha-1C chain-like K07374 TUBA; tubulin alpha
E 103815937 CPEB1; cytoplasmic polyadenylation element-binding protein 1 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 103813908 CPEB3; cytoplasmic polyadenylation element-binding protein 3 isoform X3 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 103826140 CPEB2; LOW QUALITY PROTEIN: cytoplasmic polyadenylation element-binding protein 2 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 103824097 CPEB4; cytoplasmic polyadenylation element-binding protein 4 isoform X2 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 103817328 GEMIN5; gem-associated protein 5 K13133 GEMIN5; gem associated protein 5
E 103823692 TACC3; transforming acidic coiled-coil-containing protein 3 K14283 TACC3; transforming acidic coiled-coil-containing protein 3
E 103817563 TNRC6A; trinucleotide repeat-containing gene 6A protein isoform X8 K18412 TNRC6; trinucleotide repeat-containing gene 6 protein
E 103819883 TNRC6C; trinucleotide repeat-containing gene 6C protein isoform X1 K18412 TNRC6; trinucleotide repeat-containing gene 6 protein
E 103813279 TNRC6B; trinucleotide repeat-containing gene 6B protein isoform X2 K18412 TNRC6; trinucleotide repeat-containing gene 6 protein
E 103816677 CNOT1; CCR4-NOT transcription complex subunit 1 isoform X1 K12604 CNOT1; CCR4-NOT transcription complex subunit 1
E 103813445 CNOT2; CCR4-NOT transcription complex subunit 2 K12605 CNOT2; CCR4-NOT transcription complex subunit 2
E 103813373 CNOT4; CCR4-NOT transcription complex subunit 4 isoform X2 K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]
E 103817286 CNOT6; CCR4-NOT transcription complex subunit 6 isoform X1 K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E 103823436 CNOT6L; CCR4-NOT transcription complex subunit 6-like K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E 103817329 CNOT8; CCR4-NOT transcription complex subunit 8 K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E 103825342 CNOT7; CCR4-NOT transcription complex subunit 7 K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E 103821140 uncharacterized protein KIAA0355 homolog isoform X1 K26671 GARRE1; granule associated Rac and RHOG effector protein 1
E 103815355 DIS3L2; DIS3-like exonuclease 2 isoform X1 K18758 DIS3L2; DIS3-like exonuclease 2 [EC:3.1.13.-]
E 103825040 PAN2; PAN2-PAN3 deadenylation complex catalytic subunit PAN2 isoform X2 K12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4]
E 103827337 PAN3; PAN2-PAN3 deadenylation complex subunit PAN3 isoform X1 K12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3
E 103816947 protein BTG1-like K14443 TOB; protein Tob/BTG
E 103813296 TOB2; protein Tob2 K14443 TOB; protein Tob/BTG
E 103819814 TOB1; protein Tob1 K14443 TOB; protein Tob/BTG
E 103822990 BTG4; protein BTG4 K14443 TOB; protein Tob/BTG
E 103824512 protein BTG2 K14443 TOB; protein Tob/BTG
E 103813651 BTG1; LOW QUALITY PROTEIN: protein BTG1 K14443 TOB; protein Tob/BTG
E 103818025 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter isoform X1 K18728 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter
E 103822137 PATL1; LOW QUALITY PROTEIN: protein PAT1 homolog 1 K12617 PATL1; DNA topoisomerase 2-associated protein PAT1
E 103823195 EDC3; enhancer of mRNA-decapping protein 3 K12615 EDC3; enhancer of mRNA-decapping protein 3
E 103816845 EDC4; enhancer of mRNA-decapping protein 4 K12616 EDC4; enhancer of mRNA-decapping protein 4
E 103813572 UPF2; regulator of nonsense transcripts 2 K14327 UPF2; regulator of nonsense transcripts 2
E 103816397 UPF3B; regulator of nonsense transcripts 3B K14328 UPF3; regulator of nonsense transcripts 3
E 103812387 UPF3A; regulator of nonsense transcripts 3A K14328 UPF3; regulator of nonsense transcripts 3
E 103812951 TRIM71; E3 ubiquitin-protein ligase TRIM71 K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
E 103825418 POLR2G; LOW QUALITY PROTEIN: DNA-directed RNA polymerase II subunit RPB7 K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7
E 103817583 EIF2AK2; interferon-induced, double-stranded RNA-activated protein kinase isoform X1 K16195 EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]
E 103812553 ZAR1L; LOW QUALITY PROTEIN: ZAR1-like protein K18762 ZAR1; zygote arrest protein 1
E 103826181 ZAR1; zygote arrest protein 1 K18762 ZAR1; zygote arrest protein 1
E 103812701 YTHDF3; YTH domain-containing family protein 3 K20102 YTHDF; YTH domain-containing family protein
E 103818719 YTHDF1; YTH domain-containing family protein 1 isoform X2 K20102 YTHDF; YTH domain-containing family protein
E 103822548 YTHDF2; YTH domain-containing family protein 2 K20102 YTHDF; YTH domain-containing family protein
D Stress granule specific factors
E 103813791 TIAL1; nucleolysin TIAR isoform X1 K13201 TIA1; nucleolysin TIA-1/TIAR
E 103824659 TIA1; nucleolysin TIA-1 isoform X2 K13201 TIA1; nucleolysin TIA-1/TIAR
E 103813885 PABPC1; polyadenylate-binding protein 1 K13126 PABPC; polyadenylate-binding protein
E 103818799 PABPC1L; polyadenylate-binding protein 1-like K13126 PABPC; polyadenylate-binding protein
E 103823496 PABPC4; polyadenylate-binding protein 4 K13126 PABPC; polyadenylate-binding protein
E 103812886 STAU2; double-stranded RNA-binding protein Staufen homolog 2 isoform X1 K17597 STAU; double-stranded RNA-binding protein Staufen
E 103818772 STAU1; double-stranded RNA-binding protein Staufen homolog 1 isoform X1 K17597 STAU; double-stranded RNA-binding protein Staufen
E 103816358 FMR1; synaptic functional regulator FMR1 isoform X1 K15516 FMR; fragile X mental retardation protein
E 103815315 FXR1; fragile X mental retardation syndrome-related protein 1 isoform X2 K15516 FMR; fragile X mental retardation protein
E 103821886 ELAVL1; ELAV-like protein 1 isoform X2 K13088 ELAVL1; ELAV-like protein 1
E 103817321 G3BP1; ras GTPase-activating protein-binding protein 1 isoform X1 K17265 G3BP1; Ras GTPase-activating protein-binding protein 1 [EC:5.6.2.5 5.6.2.3]
E 103823440 G3BP2; ras GTPase-activating protein-binding protein 2 isoform X1 K24983 G3BP2; Ras GTPase-activating protein-binding protein 2
E 103815250 EIF2A; eukaryotic translation initiation factor 2A isoform X1 K15026 EIF2A; translation initiation factor 2A
E 103817864 EIF3B; eukaryotic translation initiation factor 3 subunit B K03253 EIF3B; translation initiation factor 3 subunit B
E 103815326 EIF4A2; eukaryotic initiation factor 4A-II K03257 EIF4A; translation initiation factor 4A
E 103821332 EIF4A3; eukaryotic initiation factor 4A-III K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]
E 103823897 EIF4B; eukaryotic translation initiation factor 4B K03258 EIF4B; translation initiation factor 4B
E 103827041 EIF4G2; eukaryotic translation initiation factor 4 gamma 2 isoform X1 K03260 EIF4G; translation initiation factor 4G
E 103815334 EIF4G1; eukaryotic translation initiation factor 4 gamma 1 isoform X1 K03260 EIF4G; translation initiation factor 4G
E 103820961 EIF4G3; LOW QUALITY PROTEIN: eukaryotic translation initiation factor 4 gamma 3 K03260 EIF4G; translation initiation factor 4G
E 103817340 RPS6KA2; ribosomal protein S6 kinase alpha-2 isoform X1 K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E 103823526 RPS6KA1; ribosomal protein S6 kinase alpha-1 isoform X1 K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E 103816446 RPS6KA6; LOW QUALITY PROTEIN: ribosomal protein S6 kinase alpha-6 K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E 103815847 RPS6KA3; ribosomal protein S6 kinase alpha-3 isoform X1 K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E 103819084 TRAF2; TNF receptor-associated factor 2 isoform X1 K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
E 103812254 TDRD3; tudor domain-containing protein 3 isoform X1 K18404 TDRD3; tudor domain-containing protein 3
E 103812730 LARP4B; la-related protein 4B isoform X1 K18763 LARP4; la-related protein 4
E 103823882 LARP4; LOW QUALITY PROTEIN: la-related protein 4 K18763 LARP4; la-related protein 4
B mRNA degradation factors
C 5'-3' decay
D Decapping complex
E 103817149 DCP1A; mRNA-decapping enzyme 1A isoform X2 K12610 DCP1A; mRNA-decapping enzyme 1A [EC:3.-.-.-]
E 103820521 DCP1B; mRNA-decapping enzyme 1B isoform X1 K12611 DCP1B; mRNA-decapping enzyme 1B [EC:3.-.-.-]
E 103824109 DCP2; m7GpppN-mRNA hydrolase isoform X1 K12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]
E 103822774 DDX6; probable ATP-dependent RNA helicase DDX6 K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7]
E 103823195 EDC3; enhancer of mRNA-decapping protein 3 K12615 EDC3; enhancer of mRNA-decapping protein 3
E 103816845 EDC4; enhancer of mRNA-decapping protein 4 K12616 EDC4; enhancer of mRNA-decapping protein 4
E 103822137 PATL1; LOW QUALITY PROTEIN: protein PAT1 homolog 1 K12617 PATL1; DNA topoisomerase 2-associated protein PAT1
D Lsm complex
E 103822746 LSM1; U6 snRNA-associated Sm-like protein LSm1 K12620 LSM1; U6 snRNA-associated Sm-like protein LSm1
E 103817170 LSM3; U6 snRNA-associated Sm-like protein LSm3 K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3
E 103824704 LSM4; U6 snRNA-associated Sm-like protein LSm4 K12623 LSM4; U6 snRNA-associated Sm-like protein LSm4
E 103821492 LSM5; U6 snRNA-associated Sm-like protein LSm5 K12624 LSM5; U6 snRNA-associated Sm-like protein LSm5
E 103826076 LSM6; U6 snRNA-associated Sm-like protein LSm6 K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6
E 103821970 LSM7; U6 snRNA-associated Sm-like protein LSm7 K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7
E 103813469 LSM8; LSM8 homolog, U6 small nuclear RNA associated isoform X1 K12627 LSM8; U6 snRNA-associated Sm-like protein LSm8
D 5' exonucleases
E 103815415 XRN1; 5'-3' exoribonuclease 1 isoform X1 K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]
E 103819264 XRN2; 5'-3' exoribonuclease 2 K12619 XRN2; 5'-3' exoribonuclease 2 [EC:3.1.13.-]
D Other 5'-3' decay factors
E 103822804 DCPS; m7GpppX diphosphatase K12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]
E 103819771 HELZ; probable helicase with zinc finger domain isoform X1 K25168 HELZ; helicase with zinc finger domain [EC:5.6.2.-]
C 3'-5' decay
D Core exosome factors
E 103813882 EXOSC1; exosome complex component CSL4 isoform X1 K07573 CSL4; exosome complex component CSL4
E 103818998 EXOSC2; exosome complex component RRP4 K03679 RRP4; exosome complex component RRP4
E 103814214 EXOSC3; exosome complex component RRP40 K03681 RRP40; exosome complex component RRP40
E 103825659 exosome complex component RRP46-like K12590 RRP46; exosome complex component RRP46
E 103816840 EXOSC6; exosome complex component MTR3 K12587 MTR3; exosome complex component MTR3
E 103813001 EXOSC7; exosome complex component RRP42 K12589 RRP42; exosome complex component RRP42
E 103812559 EXOSC8; exosome complex component RRP43 K12586 RRP43; exosome complex component RRP43
E 103821411 EXOSC9; exosome complex component RRP45 K03678 RRP45; exosome complex component RRP45
D Exosome cofactors
E 103812588 DIS3; exosome complex exonuclease RRP44 K12585 DIS3; exosome complex exonuclease DIS3/RRP44 [EC:3.1.13.-]
E 103816112 DIS3L; DIS3-like exonuclease 1 isoform X2 K18681 DIS3L; DIS3-like exonuclease 1 [EC:3.1.13.-]
E 103820857 EXOSC10; exosome component 10 isoform X2 K12591 RRP6; exosome complex exonuclease RRP6 [EC:3.1.13.-]
E 103821358 C1D; nuclear nucleic acid-binding protein C1D K12592 C1D; exosome complex protein LRP1
E 103816735 MPHOSPH6; M-phase phosphoprotein 6 K12593 MPHOSPH6; M-phase phosphoprotein 6, animal type
D TRAMP complex
E 103816619 TENT4B; terminal nucleotidyltransferase 4A K03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19]
E 103822574 TENT4A; terminal nucleotidyltransferase 4A isoform X1 K03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19]
E 103823085 ZCCHC7; zinc finger CCHC domain-containing protein 7 K12597 AIR1_2; protein AIR1/2
E 103821095 MTREX; exosome RNA helicase MTR4 isoform X1 K12598 MTR4; ATP-dependent RNA helicase DOB1 [EC:5.6.2.6]
D Ski complex
E 103821002 TTC37; tetratricopeptide repeat protein 37 K12600 SKI3; superkiller protein 3
E 103823163 WDR61; WD repeat-containing protein 61 K12602 WDR61; WD repeat-containing protein 61
D Ccr4-NOT complex
E 103817286 CNOT6; CCR4-NOT transcription complex subunit 6 isoform X1 K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E 103823436 CNOT6L; CCR4-NOT transcription complex subunit 6-like K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E 103816677 CNOT1; CCR4-NOT transcription complex subunit 1 isoform X1 K12604 CNOT1; CCR4-NOT transcription complex subunit 1
E 103813445 CNOT2; CCR4-NOT transcription complex subunit 2 K12605 CNOT2; CCR4-NOT transcription complex subunit 2
E 103813373 CNOT4; CCR4-NOT transcription complex subunit 4 isoform X2 K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]
E 103817329 CNOT8; CCR4-NOT transcription complex subunit 8 K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E 103825342 CNOT7; CCR4-NOT transcription complex subunit 7 K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E 103814351 CNOT9; CCR4-NOT transcription complex subunit 9 K12606 RCD1; CCR4-NOT transcription complex subunit 9
E 103812950 CNOT10; CCR4-NOT transcription complex subunit 10 K12607 CNOT10; CCR4-NOT transcription complex subunit 10
D Pan complex
E 103825040 PAN2; PAN2-PAN3 deadenylation complex catalytic subunit PAN2 isoform X2 K12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4]
E 103827337 PAN3; PAN2-PAN3 deadenylation complex subunit PAN3 isoform X1 K12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3
D Other 3'-5' decay factors
E 103820559 PNLDC1; poly(A)-specific ribonuclease PNLDC1 isoform X1 K01148 PARN; poly(A)-specific ribonuclease [EC:3.1.13.4]
E 103817721 PARN; poly(A)-specific ribonuclease PARN isoform X1 K01148 PARN; poly(A)-specific ribonuclease [EC:3.1.13.4]
E 103815256 DHX36; ATP-dependent DNA/RNA helicase DHX36 K14442 DHX36; ATP-dependent RNA helicase DHX36 [EC:5.6.2.6]
E 103816947 protein BTG1-like K14443 TOB; protein Tob/BTG
E 103813296 TOB2; protein Tob2 K14443 TOB; protein Tob/BTG
E 103819814 TOB1; protein Tob1 K14443 TOB; protein Tob/BTG
E 103822990 BTG4; protein BTG4 K14443 TOB; protein Tob/BTG
E 103824512 protein BTG2 K14443 TOB; protein Tob/BTG
E 103813651 BTG1; LOW QUALITY PROTEIN: protein BTG1 K14443 TOB; protein Tob/BTG
E 103822546 NOCT; nocturnin K18764 NOCT; nocturnin [EC:3.1.3.108]
E 103825980 ERI1; 3'-5' exoribonuclease 1 isoform X1 K18416 THEX1; 3'-5' exoribonuclease 1 [EC:3.1.-.-]
E 103817885 ERI2; ERI1 exoribonuclease 2 K18417 ERI2; ERI1 exoribonuclease 2 [EC:3.1.-.-]
E 103822804 DCPS; m7GpppX diphosphatase K12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]
E 103817155 PDE12; 2',5'-phosphodiesterase 12 K19612 PDE12; 2',5'-phosphodiesterase [EC:3.1.13.4 3.1.4.-]
E 103823165 IREB2; iron-responsive element-binding protein 2 isoform X1 K22416 IREB2; iron-responsive element-binding protein 2
E 103819771 HELZ; probable helicase with zinc finger domain isoform X1 K25168 HELZ; helicase with zinc finger domain [EC:5.6.2.-]
E 103818689 HELZ2; helicase with zinc finger domain 2 K25165 HELZ2; 3'-5' exoribonuclease HELZ2 [EC:3.1.13.1 5.6.2.6]
E 103826482 NRDE2; protein NRDE2 homolog K26109 NRDE2; nuclear exosome regulator NRDE2
E 103826328 SAMD4A; protein Smaug homolog 1 isoform X3 K27396 SMG; protein Smaug
E 103819443 FOCAD; focadhesin K27498 FOCAD; focadhesin
C Other degradation factors
D RNases
E 103816415 ZC3H12B; probable ribonuclease ZC3H12B K18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]
E 103827298 ZC3H12C; probable ribonuclease ZC3H12C isoform X1 K18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]
E 103822588 ZC3H12A; endoribonuclease ZC3H12A K18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]
E 103818579 ZC3H12D; probable ribonuclease ZC3H12D K18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]
#
AProkaryotic type
B Bacterial mRNA degradation factors
C RNA degradosome components
D Ribonucreases
E 103820026 DROSHA; ribonuclease 3 K03685 rnc; ribonuclease III [EC:3.1.26.3]
E 103822790 REXO2; oligoribonuclease, mitochondrial K13288 orn; oligoribonuclease [EC:3.1.-.-]
D Helicases
D Other RNA degradosome components
E 103820786 ENO1; alpha-enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
E 103827161 ENO2; gamma-enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
E 103819244 PNPT1; polyribonucleotide nucleotidyltransferase 1, mitochondrial K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
E 103812734 PFKP; ATP-dependent 6-phosphofructokinase, platelet type isoform X3 K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
E 103815490 PFKL; ATP-dependent 6-phosphofructokinase, liver type K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
C Other RNA degradation factors
D Chaperones
E 103823790 HSPA9; stress-70 protein, mitochondrial isoform X2 K04043 dnaK; molecular chaperone DnaK
E 103814525 HSPD1; 60 kDa heat shock protein, mitochondrial K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D Others
D Bacterial Small RNA Regulators
B Archeal mRNA degradation factors
C Exosome components
D Core exosome
E 103818998 EXOSC2; exosome complex component RRP4 K03679 RRP4; exosome complex component RRP4
E 103813882 EXOSC1; exosome complex component CSL4 isoform X1 K07573 CSL4; exosome complex component CSL4
D Cofactors
E 103813001 EXOSC7; exosome complex component RRP42 K12589 RRP42; exosome complex component RRP42
D Others
!
#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: April 25, 2024